[ { "uniprot_canonical_ac": "Q5XJS5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 323, "chemical_mass": 35368.0, "gene_names": "thoc6;thoc6;wdr58;zgc:101618", "protein_name": "THO complex subunit 6 homolog", "disease": [], "cellular_component": [ { "name": "THO complex", "id": "GO:0000347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000347", "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "pmid": "" }, { "name": "transcription export complex", "id": "GO:0000346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000346", "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q5XJS5", "url": "https://www.uniprot.org/uniprotkb/Q5XJS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q5XJX0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 183, "chemical_mass": 20578.0, "gene_names": "jagn1a;jagn1a;si:ch211-283e2.4;zgc:101070", "protein_name": "Protein jagunal homolog 1-A", "disease": [ { "disease_id": "DOID:0112134", "name": "severe congenital neutropenia 6", "description": "A severe congenital neutropenia that has_material_basis_in homozygous or compound heterozygous mutation in the JAGN1 gene on chromosome 3p25.3.", "url": "https://disease-ontology.org/term/DOID:0112134", "evidence": [ { "id": "0112134", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112134" } ], "weight": 0.0 } ], "biological_process": [ { "name": "neutrophil differentiation", "id": "GO:0030223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030223", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" }, { "name": "neutrophil mediated immunity", "id": "GO:0002446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002446", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" }, { "name": "defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" }, { "name": "granulocyte colony-stimulating factor signaling pathway", "id": "GO:0038158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038158", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" }, { "name": "neutrophil migration", "id": "GO:1990266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990266", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX0", "url": "https://www.uniprot.org/uniprotkb/Q5XJX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q5XJX1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 272, "chemical_mass": 31578.0, "gene_names": "scgn;scgn;zgc:100843", "protein_name": "Secretagogin", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "pmid": "" } ], "biological_process": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "pmid": "" }, { "name": "spinal cord motor neuron differentiation", "id": "GO:0021522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021522", "evidence": [ { "database": "UniProtKB", "id": "Q5XJX1", "url": "https://www.uniprot.org/uniprotkb/Q5XJX1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q642H2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 119, "chemical_mass": 13525.0, "gene_names": "crebl2;crebl2;zgc:92620;zgc:92797", "protein_name": "cAMP-responsive element-binding protein-like 2", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" }, { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" }, { "name": "positive regulation of lipid biosynthetic process", "id": "GO:0046889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046889", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" }, { "name": "positive regulation of D-glucose import", "id": "GO:0046326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046326", "evidence": [ { "database": "UniProtKB", "id": "Q642H2", "url": "https://www.uniprot.org/uniprotkb/Q642H2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q642H3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 420, "chemical_mass": 48999.0, "gene_names": "sept8a;fb22a03;sept8a;sept8;septin8a;wu:fb22a03", "protein_name": "Septin-8-A", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" } ], "cellular_component": [ { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "Q642H3", "url": "https://www.uniprot.org/uniprotkb/Q642H3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q642H9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 263, "chemical_mass": 29688.0, "gene_names": "rps4x;rps4x;rps4;wu:fa91h09;zgc:92076", "protein_name": "Small ribosomal subunit protein eS4", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" } ], "biological_process": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" } ], "cellular_component": [ { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "Q642H9", "url": "https://www.uniprot.org/uniprotkb/Q642H9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q642J4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 317, "chemical_mass": 35901.0, "gene_names": "impact;CH73-159L23.5;impact;zgc:103672", "protein_name": "Protein IMPACT", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" }, { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" }, { "name": "neuron projection extension", "id": "GO:1990138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990138", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" }, { "name": "GCN2-mediated signaling", "id": "GO:0140469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140469", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" }, { "name": "regulation of cytoplasmic translational initiation in response to stress", "id": "GO:1990611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990611", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "Q642J4", "url": "https://www.uniprot.org/uniprotkb/Q642J4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q642M9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q642M9", "url": "https://www.uniprot.org/uniprotkb/Q642M9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 334, "chemical_mass": 36566.0, "gene_names": "dhdh;ch211-203b17.3;zgc:101723", "protein_name": "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase", "disease": [], "molecular_function": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q642M9", "url": "https://www.uniprot.org/uniprotkb/Q642M9" } ], "pmid": "" }, { "name": "trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity", "id": "GO:0047115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047115", "evidence": [ { "database": "UniProtKB", "id": "Q642M9", "url": "https://www.uniprot.org/uniprotkb/Q642M9" } ], "pmid": "" }, { "name": "D-xylose 1-dehydrogenase (NADP+) activity", "id": "GO:0047837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047837", "evidence": [ { "database": "UniProtKB", "id": "Q642M9", "url": "https://www.uniprot.org/uniprotkb/Q642M9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66HV4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 953, "chemical_mass": 107032.0, "gene_names": "copb1;copb1;happy;hap;id:ibd5034;wu:fc66c05;zgc:92482", "protein_name": "Coatomer subunit beta", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "pmid": "" }, { "name": "notochord development", "id": "GO:0030903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030903", "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "pmid": "" }, { "name": "somite development", "id": "GO:0061053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061053", "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "Q66HV4", "url": "https://www.uniprot.org/uniprotkb/Q66HV4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66HV9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66HV9", "url": "https://www.uniprot.org/uniprotkb/Q66HV9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 622, "chemical_mass": 70446.0, "gene_names": "lingo1b;lingo1b;lingo1;si:ch211-116a8.1;zgc:92338", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B", "disease": [ { "disease_id": "DOID:0081225", "name": "autosomal recessive intellectual developmental disorder 64", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the LINGO1 gene on chromosome 15q24.", "url": "https://disease-ontology.org/term/DOID:0081225", "evidence": [ { "id": "0081225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081225" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q66HV9", "url": "https://www.uniprot.org/uniprotkb/Q66HV9" } ], "pmid": "" } ], "biological_process": [ { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "Q66HV9", "url": "https://www.uniprot.org/uniprotkb/Q66HV9" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "Q66HV9", "url": "https://www.uniprot.org/uniprotkb/Q66HV9" } ], "pmid": "" } ], "molecular_function": [ { "name": "epidermal growth factor receptor binding", "id": "GO:0005154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005154", "evidence": [ { "database": "UniProtKB", "id": "Q66HV9", "url": "https://www.uniprot.org/uniprotkb/Q66HV9" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "Q66HV9", "url": "https://www.uniprot.org/uniprotkb/Q66HV9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Asn146", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 146, "start_aa": "Asn", "end_pos": 146, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn146", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Asn204", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 204, "start_aa": "Asn", "end_pos": 204, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn204", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Asn266", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 266, "start_aa": "Asn", "end_pos": 266, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn266", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Asn276", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 276, "start_aa": "Asn", "end_pos": 276, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn276", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Asn295", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 295, "start_aa": "Asn", "end_pos": 295, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn295", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Asn343", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 343, "start_aa": "Asn", "end_pos": 343, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn343", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Asn494", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 494, "start_aa": "Asn", "end_pos": 494, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn494", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Asn507", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 507, "start_aa": "Asn", "end_pos": 507, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn507", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "528", "end_pos": "528", "site_lbl": "Asn528", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 528, "start_aa": "Asn", "end_pos": 528, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn528", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HV9-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Asn544", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 544, "start_aa": "Asn", "end_pos": 544, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn544", "evidence": [ { "id": "Q66HV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HV9#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66HW4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66HW4", "url": "https://www.uniprot.org/uniprotkb/Q66HW4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 407, "chemical_mass": 44641.0, "gene_names": "glmp;glmp;si:dkey-263h23.3;zgc:92308", "protein_name": "Glycosylated lysosomal membrane protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q66HW4", "url": "https://www.uniprot.org/uniprotkb/Q66HW4" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q66HW4", "url": "https://www.uniprot.org/uniprotkb/Q66HW4" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q66HW4", "url": "https://www.uniprot.org/uniprotkb/Q66HW4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "Q66HW4", "url": "https://www.uniprot.org/uniprotkb/Q66HW4" } ], "pmid": "" }, { "name": "protein localization to lysosome", "id": "GO:0061462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061462", "evidence": [ { "database": "UniProtKB", "id": "Q66HW4", "url": "https://www.uniprot.org/uniprotkb/Q66HW4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Asn132", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 132, "start_aa": "Asn", "end_pos": 132, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn132", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Asn160", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 160, "start_aa": "Asn", "end_pos": 160, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn160", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "164", "end_pos": "164", "site_lbl": "Asn164", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 164, "start_aa": "Asn", "end_pos": 164, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn164", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Asn183", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 183, "start_aa": "Asn", "end_pos": 183, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn183", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Asn210", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 210, "start_aa": "Asn", "end_pos": 210, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn210", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "226", "end_pos": "226", "site_lbl": "Asn226", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 226, "start_aa": "Asn", "end_pos": 226, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn226", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Asn272", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 272, "start_aa": "Asn", "end_pos": 272, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn272", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Asn331", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 331, "start_aa": "Asn", "end_pos": 331, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn331", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Asn63", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 63, "start_aa": "Asn", "end_pos": 63, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn63", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Asn84", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 84, "start_aa": "Asn", "end_pos": 84, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn84", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66HW4-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Asn99", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 99, "start_aa": "Asn", "end_pos": 99, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn99", "evidence": [ { "id": "Q66HW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HW4#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I06-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I06", "url": "https://www.uniprot.org/uniprotkb/Q66I06" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 191, "chemical_mass": 22015.0, "gene_names": "ggact.2;GGACT A;GGACT B;GGACT;ggact.2;zgc:92115", "protein_name": "Gamma-glutamylaminecyclotransferase B", "disease": [], "biological_process": [ { "name": "modified amino acid catabolic process", "id": "GO:0042219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042219", "evidence": [ { "database": "UniProtKB", "id": "Q66I06", "url": "https://www.uniprot.org/uniprotkb/Q66I06" } ], "pmid": "" } ], "molecular_function": [ { "name": "gamma-glutamylaminecyclotransferase activity", "id": "GO:0061929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061929", "evidence": [ { "database": "UniProtKB", "id": "Q66I06", "url": "https://www.uniprot.org/uniprotkb/Q66I06" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q66I06", "url": "https://www.uniprot.org/uniprotkb/Q66I06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I12-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 486, "chemical_mass": 56173.0, "gene_names": "ccdc47;ccdc47;zgc:92099", "protein_name": "PAT complex subunit CCDC47", "disease": [], "biological_process": [ { "name": "protein insertion into ER membrane", "id": "GO:0045048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045048", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" }, { "name": "multi-pass transmembrane protein insertion into ER membrane", "id": "GO:0160063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160063", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum membrane", "id": "GO:0030867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030867", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" }, { "name": "multi-pass translocon complex", "id": "GO:0160064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160064", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "Q66I12", "url": "https://www.uniprot.org/uniprotkb/Q66I12" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I21-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I21", "url": "https://www.uniprot.org/uniprotkb/Q66I21" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 487, "chemical_mass": 53354.0, "gene_names": "aldh8a1;aldh8a1;fi34g05;wu:fi34g05;zgc:92068", "protein_name": "2-aminomuconic semialdehyde dehydrogenase", "disease": [], "biological_process": [ { "name": "L-kynurenine catabolic process", "id": "GO:0097053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097053", "evidence": [ { "database": "UniProtKB", "id": "Q66I21", "url": "https://www.uniprot.org/uniprotkb/Q66I21" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "Q66I21", "url": "https://www.uniprot.org/uniprotkb/Q66I21" } ], "pmid": "" }, { "name": "retinoic acid metabolic process", "id": "GO:0042573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042573", "evidence": [ { "database": "UniProtKB", "id": "Q66I21", "url": "https://www.uniprot.org/uniprotkb/Q66I21" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66I21", "url": "https://www.uniprot.org/uniprotkb/Q66I21" } ], "pmid": "" } ], "molecular_function": [ { "name": "retinal dehydrogenase (NAD+) activity", "id": "GO:0001758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001758", "evidence": [ { "database": "UniProtKB", "id": "Q66I21", "url": "https://www.uniprot.org/uniprotkb/Q66I21" } ], "pmid": "" }, { "name": "aminomuconate-semialdehyde dehydrogenase activity", "id": "GO:0047102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047102", "evidence": [ { "database": "UniProtKB", "id": "Q66I21", "url": "https://www.uniprot.org/uniprotkb/Q66I21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I22-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 896, "chemical_mass": 103274.0, "gene_names": "srrt;CHUNP6881;ars2;ch211-283g2.4;srrt;zgc:92060", "protein_name": "Serrate RNA effector molecule homolog", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" }, { "name": "primary miRNA processing", "id": "GO:0031053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031053", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" }, { "name": "RNA metabolic process", "id": "GO:0016070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016070", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q66I22", "url": "https://www.uniprot.org/uniprotkb/Q66I22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q66I22-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Thr290", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I24-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I24", "url": "https://www.uniprot.org/uniprotkb/Q66I24" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 414, "chemical_mass": 47129.0, "gene_names": "ass1;ass1;ass;wu:fb95a04;wu:fc01e08;zgc:92051", "protein_name": "Argininosuccinate synthase", "disease": [ { "disease_id": "DOID:0070340", "name": "classic citrullinemia", "description": "A citrullinemia that has_material_basis_in homozygous or compound heterozygous mutation in the ASS1 gene, which encodes argininosuccinate synthetase, on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:0070340", "evidence": [ { "id": "0070340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070340" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9273", "name": "citrullinemia", "description": "An inherited urea cycle disorder that involves the accumulation of ammonia and other toxic substances in the blood.", "url": "https://disease-ontology.org/term/DOID:9273", "evidence": [ { "id": "9273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9273" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q66I24", "url": "https://www.uniprot.org/uniprotkb/Q66I24" } ], "pmid": "" }, { "name": "argininosuccinate synthase activity", "id": "GO:0004055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004055", "evidence": [ { "database": "UniProtKB", "id": "Q66I24", "url": "https://www.uniprot.org/uniprotkb/Q66I24" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66I24", "url": "https://www.uniprot.org/uniprotkb/Q66I24" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q66I24", "url": "https://www.uniprot.org/uniprotkb/Q66I24" } ], "pmid": "" } ], "biological_process": [ { "name": "urea cycle", "id": "GO:0000050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000050", "evidence": [ { "database": "UniProtKB", "id": "Q66I24", "url": "https://www.uniprot.org/uniprotkb/Q66I24" } ], "pmid": "" }, { "name": "argininosuccinate metabolic process", "id": "GO:0000053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000053", "evidence": [ { "database": "UniProtKB", "id": "Q66I24", "url": "https://www.uniprot.org/uniprotkb/Q66I24" } ], "pmid": "" }, { "name": "L-arginine biosynthetic process", "id": "GO:0006526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006526", "evidence": [ { "database": "UniProtKB", "id": "Q66I24", "url": "https://www.uniprot.org/uniprotkb/Q66I24" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I51-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I51", "url": "https://www.uniprot.org/uniprotkb/Q66I51" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 262, "chemical_mass": 28598.0, "gene_names": "tmem55bb;pip4p1b;si:ch211-243g6.4;tmem55bb", "protein_name": "Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-B", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity", "id": "GO:0034597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034597", "evidence": [ { "database": "UniProtKB", "id": "Q66I51", "url": "https://www.uniprot.org/uniprotkb/Q66I51" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q66I51", "url": "https://www.uniprot.org/uniprotkb/Q66I51" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q66I51", "url": "https://www.uniprot.org/uniprotkb/Q66I51" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q66I51", "url": "https://www.uniprot.org/uniprotkb/Q66I51" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "Q66I51", "url": "https://www.uniprot.org/uniprotkb/Q66I51" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "Q66I51", "url": "https://www.uniprot.org/uniprotkb/Q66I51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I61-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I61", "url": "https://www.uniprot.org/uniprotkb/Q66I61" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 224, "chemical_mass": 25789.0, "gene_names": "steep1;STEEP;steep1;zgc:103697", "protein_name": "STING ER exit protein", "disease": [ { "disease_id": "DOID:0112054", "name": "non-syndromic X-linked intellectual disability 107", "description": "A non-syndromic X-linked intellectual disability characterized by mild to moderate intellectual disability that has_material_basis_in heterozygous or hemizygous mutation in CXorf56 on chromosome Xq24.", "url": "https://disease-ontology.org/term/DOID:0112054", "evidence": [ { "id": "0112054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112054" } ], "weight": 0.0 } ], "biological_process": [ { "name": "endoplasmic reticulum membrane organization", "id": "GO:0090158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090158", "evidence": [ { "database": "UniProtKB", "id": "Q66I61", "url": "https://www.uniprot.org/uniprotkb/Q66I61" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q66I61", "url": "https://www.uniprot.org/uniprotkb/Q66I61" } ], "pmid": "" }, { "name": "protein exit from endoplasmic reticulum", "id": "GO:0032527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032527", "evidence": [ { "database": "UniProtKB", "id": "Q66I61", "url": "https://www.uniprot.org/uniprotkb/Q66I61" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q66I61", "url": "https://www.uniprot.org/uniprotkb/Q66I61" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66I61", "url": "https://www.uniprot.org/uniprotkb/Q66I61" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "Q66I61", "url": "https://www.uniprot.org/uniprotkb/Q66I61" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q66I61", "url": "https://www.uniprot.org/uniprotkb/Q66I61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I67-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 132, "chemical_mass": 15287.0, "gene_names": "ift20;ift20;zgc:103674", "protein_name": "Intraflagellar transport protein 20 homolog", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "intraciliary transport particle", "id": "GO:0030990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030990", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" }, { "name": "regulation of platelet-derived growth factor receptor-alpha signaling pathway", "id": "GO:2000583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000583", "evidence": [ { "database": "UniProtKB", "id": "Q66I67", "url": "https://www.uniprot.org/uniprotkb/Q66I67" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I71-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I71", "url": "https://www.uniprot.org/uniprotkb/Q66I71" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 277, "chemical_mass": 31457.0, "gene_names": "uck1;uck1;zgc:103645", "protein_name": "Uridine-cytidine kinase 1", "disease": [ { "disease_id": "DOID:573", "name": "nerve compression syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:573", "evidence": [ { "id": "573", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:573" } ], "weight": 0.0 } ], "biological_process": [ { "name": "UMP salvage", "id": "GO:0044206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044206", "evidence": [ { "database": "UniProtKB", "id": "Q66I71", "url": "https://www.uniprot.org/uniprotkb/Q66I71" } ], "pmid": "" }, { "name": "CTP salvage", "id": "GO:0044211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044211", "evidence": [ { "database": "UniProtKB", "id": "Q66I71", "url": "https://www.uniprot.org/uniprotkb/Q66I71" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q66I71", "url": "https://www.uniprot.org/uniprotkb/Q66I71" } ], "pmid": "" }, { "name": "uridine kinase activity", "id": "GO:0004849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004849", "evidence": [ { "database": "UniProtKB", "id": "Q66I71", "url": "https://www.uniprot.org/uniprotkb/Q66I71" } ], "pmid": "" }, { "name": "cytidine kinase activity", "id": "GO:0043771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043771", "evidence": [ { "database": "UniProtKB", "id": "Q66I71", "url": "https://www.uniprot.org/uniprotkb/Q66I71" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66I71", "url": "https://www.uniprot.org/uniprotkb/Q66I71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I75-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I75", "url": "https://www.uniprot.org/uniprotkb/Q66I75" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 241, "chemical_mass": 27231.0, "gene_names": "apip;APIP;apip;zgc:103619", "protein_name": "Methylthioribulose-1-phosphate dehydratase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66I75", "url": "https://www.uniprot.org/uniprotkb/Q66I75" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q66I75", "url": "https://www.uniprot.org/uniprotkb/Q66I75" } ], "pmid": "" }, { "name": "methylthioribulose 1-phosphate dehydratase activity", "id": "GO:0046570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046570", "evidence": [ { "database": "UniProtKB", "id": "Q66I75", "url": "https://www.uniprot.org/uniprotkb/Q66I75" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q66I75", "url": "https://www.uniprot.org/uniprotkb/Q66I75" } ], "pmid": "" }, { "name": "L-methionine salvage from methylthioadenosine", "id": "GO:0019509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019509", "evidence": [ { "database": "UniProtKB", "id": "Q66I75", "url": "https://www.uniprot.org/uniprotkb/Q66I75" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66I79-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I79", "url": "https://www.uniprot.org/uniprotkb/Q66I79" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 94, "chemical_mass": 10153.0, "gene_names": "selenok;selenok;selk;si:ch1073-219o6.1;zgc:103591", "protein_name": "Selenoprotein K", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q66I79", "url": "https://www.uniprot.org/uniprotkb/Q66I79" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q66I79", "url": "https://www.uniprot.org/uniprotkb/Q66I79" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q66I79", "url": "https://www.uniprot.org/uniprotkb/Q66I79" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q66I79", "url": "https://www.uniprot.org/uniprotkb/Q66I79" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "Q66I79", "url": "https://www.uniprot.org/uniprotkb/Q66I79" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "Q66I79", "url": "https://www.uniprot.org/uniprotkb/Q66I79" } ], "pmid": "" }, { "name": "protein palmitoylation", "id": "GO:0018345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018345", "evidence": [ { "database": "UniProtKB", "id": "Q66I79", "url": "https://www.uniprot.org/uniprotkb/Q66I79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q66I79-1", "start_pos": "83", "end_pos": "83", "site_lbl": "Thr83", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 83, "start_aa": "Thr", "end_pos": 83, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr83", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66JN8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 252, "chemical_mass": 28355.0, "gene_names": "cplane2;cplane2;im:7136213;rsg1;zgc:101035;zgc:113864", "protein_name": "Ciliogenesis and planar polarity effector 2", "disease": [ { "disease_id": "DOID:0050545", "name": "visceral heterotaxy", "description": "A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.", "url": "https://disease-ontology.org/term/DOID:0050545", "evidence": [ { "id": "0050545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050545" } ], "weight": 0.0 }, { "disease_id": "DOID:14679", "name": "VACTERL association", "description": "A syndrome that is characterized by the presence of at least three of the following: vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities.", "url": "https://disease-ontology.org/term/DOID:14679", "evidence": [ { "id": "14679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14679" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "regulation of vesicle fusion", "id": "GO:0031338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031338", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "regulation of exocytosis", "id": "GO:0017157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017157", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" } ], "cellular_component": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "Q66JN8", "url": "https://www.uniprot.org/uniprotkb/Q66JN8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q66L51-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66L51", "url": "https://www.uniprot.org/uniprotkb/Q66L51" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 327, "chemical_mass": 37351.0, "gene_names": "coq5;coq5;zgc:92445", "protein_name": "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "disease": [ { "disease_id": "DOID:0050730", "name": "coenzyme Q10 deficiency disease", "description": "A mitochondrial metabolism disease that is characterized by a deficiency of CoQ10 resulting from reduced biosynthesis.", "url": "https://disease-ontology.org/term/DOID:0050730", "evidence": [ { "id": "0050730", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050730" } ], "weight": 0.0 }, { "disease_id": "DOID:0112138", "name": "primary coenzyme Q10 deficiency 9", "description": "A coenzyme Q10 deficiency disease characterized by onset in the first decade of life of cerebellar ataxia associated with cerebellar atrophy that has_material_basis_in mutation homozygous or compound heterozygous in the COQ5 gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0112138", "evidence": [ { "id": "0112138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112138" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "Q66L51", "url": "https://www.uniprot.org/uniprotkb/Q66L51" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "Q66L51", "url": "https://www.uniprot.org/uniprotkb/Q66L51" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q66L51", "url": "https://www.uniprot.org/uniprotkb/Q66L51" } ], "pmid": "" } ], "molecular_function": [ { "name": "2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity", "id": "GO:0008425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008425", "evidence": [ { "database": "UniProtKB", "id": "Q66L51", "url": "https://www.uniprot.org/uniprotkb/Q66L51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q68EH7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 250, "chemical_mass": 28616.0, "gene_names": "hoxc8a;cb341;hoxc8a;hoxc8;si:dkey-81p22.5;z-179;zgc:91832", "protein_name": "Homeobox protein Hox-C8a", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "pmid": "" }, { "name": "exocrine pancreas development", "id": "GO:0031017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031017", "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "pmid": "" }, { "name": "embryonic pectoral fin morphogenesis", "id": "GO:0035118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035118", "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q68EH7", "url": "https://www.uniprot.org/uniprotkb/Q68EH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q68EK9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 88, "chemical_mass": 9942.0, "gene_names": "cdc26;apc12;cdc26;si:dkey-190c14.5;zgc:100965", "protein_name": "Anaphase-promoting complex subunit CDC26", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "pmid": "" }, { "name": "protein branched polyubiquitination", "id": "GO:0141198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141198", "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "pmid": "" } ], "cellular_component": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q68EK9", "url": "https://www.uniprot.org/uniprotkb/Q68EK9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q68EL3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68EL3", "url": "https://www.uniprot.org/uniprotkb/Q68EL3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 110, "chemical_mass": 12348.0, "gene_names": "bet1l;zgc:100789", "protein_name": "BET1-like protein", "disease": [ { "disease_id": "DOID:13223", "name": "uterine fibroid", "description": "An uterine benign neoplasm derived from the smooth muscle layer of the uterus.", "url": "https://disease-ontology.org/term/DOID:13223", "evidence": [ { "id": "13223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13223" } ], "weight": 0.0 }, { "disease_id": "DOID:2870", "name": "endometrial adenocarcinoma", "description": "An endometrial carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2870", "evidence": [ { "id": "2870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2870" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q68EL3", "url": "https://www.uniprot.org/uniprotkb/Q68EL3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q68EL3", "url": "https://www.uniprot.org/uniprotkb/Q68EL3" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "Q68EL3", "url": "https://www.uniprot.org/uniprotkb/Q68EL3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q68EL3", "url": "https://www.uniprot.org/uniprotkb/Q68EL3" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q68EL3", "url": "https://www.uniprot.org/uniprotkb/Q68EL3" } ], "pmid": "" }, { "name": "regulation of retrograde vesicle-mediated transport, Golgi to ER", "id": "GO:2000156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000156", "evidence": [ { "database": "UniProtKB", "id": "Q68EL3", "url": "https://www.uniprot.org/uniprotkb/Q68EL3" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "Q68EL3", "url": "https://www.uniprot.org/uniprotkb/Q68EL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q68EL6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 462, "chemical_mass": 51501.0, "gene_names": "nfil3;E4BP4-1;nfil3;zgc:100867", "protein_name": "Nuclear factor interleukin-3-regulated protein", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" }, { "name": "myeloid cell development", "id": "GO:0061515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061515", "evidence": [ { "database": "UniProtKB", "id": "Q68EL6", "url": "https://www.uniprot.org/uniprotkb/Q68EL6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6AXJ9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 350, "chemical_mass": 40810.0, "gene_names": "cdkl1;cdkl1;zgc:101002", "protein_name": "Cyclin-dependent kinase-like 1", "disease": [], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ9", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6AXL4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AXL4", "url": "https://www.uniprot.org/uniprotkb/Q6AXL4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 192, "chemical_mass": 21984.0, "gene_names": "ncaldb;ncaldb;ncald;si:dkey-21k18.3;zgc:100982", "protein_name": "Neurocalcin-delta B", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL4", "url": "https://www.uniprot.org/uniprotkb/Q6AXL4" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL4", "url": "https://www.uniprot.org/uniprotkb/Q6AXL4" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL4", "url": "https://www.uniprot.org/uniprotkb/Q6AXL4" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL4", "url": "https://www.uniprot.org/uniprotkb/Q6AXL4" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL4", "url": "https://www.uniprot.org/uniprotkb/Q6AXL4" } ], "pmid": "" }, { "name": "regulation of axon extension involved in axon guidance", "id": "GO:0048841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048841", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL4", "url": "https://www.uniprot.org/uniprotkb/Q6AXL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6AZA0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AZA0", "url": "https://www.uniprot.org/uniprotkb/Q6AZA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 420, "chemical_mass": 44342.0, "gene_names": "acat1;acat1;fd16h07;fd20g06;wu:fd16h07;wu:fd20g06;zgc:86832", "protein_name": "Acetyl-CoA acetyltransferase, mitochondrial", "disease": [ { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:14723", "name": "beta-ketothiolase deficiency", "description": "An amino acid metabolic disorder characterized by inability to process isoleucine and ketones, has_symptom recurrent ketoacidotic attacks in infancy marked by vomiting, lethargy, dehydration, and seizures, and has_material_basis_in mutation in the ACAT1 gene of chromosome 11q22.3 responsible for producing the ACAT1 enzyme in mitochondria, which processes isoleucine and ketones.", "url": "https://disease-ontology.org/term/DOID:14723", "evidence": [ { "id": "14723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14723" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2978", "name": "carbohydrate metabolic disorder", "description": "An inherited metabolic disorder that affect the catabolism and anabolism of carbohydrates.", "url": "https://disease-ontology.org/term/DOID:2978", "evidence": [ { "id": "2978", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2978" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6AZA0", "url": "https://www.uniprot.org/uniprotkb/Q6AZA0" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "Q6AZA0", "url": "https://www.uniprot.org/uniprotkb/Q6AZA0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6AZA0", "url": "https://www.uniprot.org/uniprotkb/Q6AZA0" } ], "pmid": "" }, { "name": "acetyl-CoA C-acetyltransferase activity", "id": "GO:0003985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003985", "evidence": [ { "database": "UniProtKB", "id": "Q6AZA0", "url": "https://www.uniprot.org/uniprotkb/Q6AZA0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6AZD3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AZD3", "url": "https://www.uniprot.org/uniprotkb/Q6AZD3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 192, "chemical_mass": 21838.0, "gene_names": "meaf6;fj63g06;meaf6;wu:fj63g06;zgc:100869", "protein_name": "Chromatin modification-related protein MEAF6", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD3", "url": "https://www.uniprot.org/uniprotkb/Q6AZD3" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD3", "url": "https://www.uniprot.org/uniprotkb/Q6AZD3" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD3", "url": "https://www.uniprot.org/uniprotkb/Q6AZD3" } ], "pmid": "" }, { "name": "MOZ/MORF histone acetyltransferase complex", "id": "GO:0070776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070776", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD3", "url": "https://www.uniprot.org/uniprotkb/Q6AZD3" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD3", "url": "https://www.uniprot.org/uniprotkb/Q6AZD3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD3", "url": "https://www.uniprot.org/uniprotkb/Q6AZD3" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD3", "url": "https://www.uniprot.org/uniprotkb/Q6AZD3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6AZD4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AZD4", "url": "https://www.uniprot.org/uniprotkb/Q6AZD4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 183, "chemical_mass": 20699.0, "gene_names": "immp2l;immp2l;zgc:100888", "protein_name": "Mitochondrial inner membrane protease subunit 2", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane peptidase complex", "id": "GO:0042720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042720", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD4", "url": "https://www.uniprot.org/uniprotkb/Q6AZD4" } ], "pmid": "" } ], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD4", "url": "https://www.uniprot.org/uniprotkb/Q6AZD4" } ], "pmid": "" }, { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD4", "url": "https://www.uniprot.org/uniprotkb/Q6AZD4" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD4", "url": "https://www.uniprot.org/uniprotkb/Q6AZD4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing involved in protein targeting to mitochondrion", "id": "GO:0006627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006627", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD4", "url": "https://www.uniprot.org/uniprotkb/Q6AZD4" } ], "pmid": "" }, { "name": "signal peptide processing", "id": "GO:0006465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006465", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD4", "url": "https://www.uniprot.org/uniprotkb/Q6AZD4" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q6AZD4", "url": "https://www.uniprot.org/uniprotkb/Q6AZD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DBR0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 358, "chemical_mass": 40133.0, "gene_names": "rpusd4;rpusd4;si:ch211-14i3.3;zgc:92006", "protein_name": "Pseudouridylate synthase RPUSD4, mitochondrial", "disease": [], "biological_process": [ { "name": "enzyme-directed rRNA pseudouridine synthesis", "id": "GO:0000455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000455", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" }, { "name": "tRNA pseudouridine synthase activity", "id": "GO:0106029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106029", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q6DBR0", "url": "https://www.uniprot.org/uniprotkb/Q6DBR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DBR0-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Thr182", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 182, "start_aa": "Thr", "end_pos": 182, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr182", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DBU8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DBU8", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 454, "chemical_mass": 51811.0, "gene_names": "liph;fb08f08;liph;lipia;wu:fb08f08;zgc:91985", "protein_name": "Lipase member H", "disease": [ { "disease_id": "DOID:0110704", "name": "hypotrichosis 7", "description": "A hypotrichosis that has_material_basis_in a autosomal recessive mutation of the LIPH gene on chromosome 3q27.2.", "url": "https://disease-ontology.org/term/DOID:0110704", "evidence": [ { "id": "0110704", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110704" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6DBU8", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DBU8", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "Q6DBU8", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q6DBU8", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "Q6DBU8", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "Q6DBU8", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8" } ], "pmid": "" }, { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "Q6DBU8", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DBU8-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Asn137", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 137, "start_aa": "Asn", "end_pos": 137, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn137", "evidence": [ { "id": "Q6DBU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DBU8-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Asn151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 151, "start_aa": "Asn", "end_pos": 151, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn151", "evidence": [ { "id": "Q6DBU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DBU8-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Asn267", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 267, "start_aa": "Asn", "end_pos": 267, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn267", "evidence": [ { "id": "Q6DBU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DBU8-1", "start_pos": "358", "end_pos": "358", "site_lbl": "Asn358", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 358, "start_aa": "Asn", "end_pos": 358, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn358", "evidence": [ { "id": "Q6DBU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DBU8-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Asn73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 73, "start_aa": "Asn", "end_pos": 73, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn73", "evidence": [ { "id": "Q6DBU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DBU8#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DBV4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 279, "chemical_mass": 31403.0, "gene_names": "phospho1;phospho1;sb:cb839;zgc:92423", "protein_name": "Probable phosphatase phospho1", "disease": [], "molecular_function": [ { "name": "phosphocholine phosphatase activity", "id": "GO:0052731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052731", "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "pmid": "" }, { "name": "phosphoethanolamine phosphatase activity", "id": "GO:0052732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052732", "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular membrane-bounded organelle", "id": "GO:0065010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065010", "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "pmid": "" }, { "name": "extracellular vesicle", "id": "GO:1903561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903561", "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "Q6DBV4", "url": "https://www.uniprot.org/uniprotkb/Q6DBV4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DBY0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DBY0", "url": "https://www.uniprot.org/uniprotkb/Q6DBY0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 649, "chemical_mass": 74148.0, "gene_names": "nup85;nup85;pcnt1;zgc:100943", "protein_name": "Nuclear pore complex protein Nup85", "disease": [ { "disease_id": "DOID:0080392", "name": "nephrotic syndrome type 17", "description": "A familial nephrotic syndrome that has_material_basis_in by homozygous or compound heterozygous mutation in the NUP85 gene on chromosome 17q25.", "url": "https://disease-ontology.org/term/DOID:0080392", "evidence": [ { "id": "0080392", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080392" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nephron development", "id": "GO:0072006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072006", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY0", "url": "https://www.uniprot.org/uniprotkb/Q6DBY0" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY0", "url": "https://www.uniprot.org/uniprotkb/Q6DBY0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY0", "url": "https://www.uniprot.org/uniprotkb/Q6DBY0" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY0", "url": "https://www.uniprot.org/uniprotkb/Q6DBY0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY0", "url": "https://www.uniprot.org/uniprotkb/Q6DBY0" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY0", "url": "https://www.uniprot.org/uniprotkb/Q6DBY0" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY0", "url": "https://www.uniprot.org/uniprotkb/Q6DBY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DBY5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DBY5", "url": "https://www.uniprot.org/uniprotkb/Q6DBY5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 471, "chemical_mass": 51264.0, "gene_names": "uevld;uev3;uevld;wu:fb14b11;zgc:100959", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 3", "disease": [], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY5", "url": "https://www.uniprot.org/uniprotkb/Q6DBY5" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY5", "url": "https://www.uniprot.org/uniprotkb/Q6DBY5" } ], "pmid": "" }, { "name": "carboxylic acid metabolic process", "id": "GO:0019752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019752", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY5", "url": "https://www.uniprot.org/uniprotkb/Q6DBY5" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY5", "url": "https://www.uniprot.org/uniprotkb/Q6DBY5" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY5", "url": "https://www.uniprot.org/uniprotkb/Q6DBY5" } ], "pmid": "" } ], "cellular_component": [ { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "Q6DBY5", "url": "https://www.uniprot.org/uniprotkb/Q6DBY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DEI8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DEI8", "url": "https://www.uniprot.org/uniprotkb/Q6DEI8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 146, "chemical_mass": 15755.0, "gene_names": "chchd4;chchd4a;chchd4;fc10g04;mia40;si:dkey-202e22.1;wu:fc10g04;zgc:100849", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "disease": [], "biological_process": [ { "name": "protein import into mitochondrial intermembrane space", "id": "GO:0045041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045041", "evidence": [ { "database": "UniProtKB", "id": "Q6DEI8", "url": "https://www.uniprot.org/uniprotkb/Q6DEI8" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex assembly", "id": "GO:0033108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033108", "evidence": [ { "database": "UniProtKB", "id": "Q6DEI8", "url": "https://www.uniprot.org/uniprotkb/Q6DEI8" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "Q6DEI8", "url": "https://www.uniprot.org/uniprotkb/Q6DEI8" } ], "pmid": "" }, { "name": "mitochondrial disulfide relay system", "id": "GO:0160203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160203", "evidence": [ { "database": "UniProtKB", "id": "Q6DEI8", "url": "https://www.uniprot.org/uniprotkb/Q6DEI8" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q6DEI8", "url": "https://www.uniprot.org/uniprotkb/Q6DEI8" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "Q6DEI8", "url": "https://www.uniprot.org/uniprotkb/Q6DEI8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DEL1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 465, "chemical_mass": 50678.0, "gene_names": "slc38a7;cb389;fb71c10;fi23b07;sb:cb389;slc38a7;wu:fb71c10;wu:fi23b07;zgc:100802", "protein_name": "Sodium-coupled neutral amino acid transporter 7", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" } ], "biological_process": [ { "name": "glutamine transport", "id": "GO:0006868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006868", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "asparagine transport", "id": "GO:0006867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006867", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-glutamine transmembrane transporter activity", "id": "GO:0015186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015186", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "L-asparagine transmembrane transporter activity", "id": "GO:0015182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015182", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "L-asparagine:sodium symporter activity", "id": "GO:0140901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140901", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" }, { "name": "L-glutamine:sodium symporter activity", "id": "GO:0140902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140902", "evidence": [ { "database": "UniProtKB", "id": "Q6DEL1", "url": "https://www.uniprot.org/uniprotkb/Q6DEL1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DG03-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DG03", "url": "https://www.uniprot.org/uniprotkb/Q6DG03" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 645, "chemical_mass": 71268.0, "gene_names": "dmtf1;dmtf1;si:dkey-153k10.8;zgc:92448", "protein_name": "Cyclin-D-binding Myb-like transcription factor 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DG03", "url": "https://www.uniprot.org/uniprotkb/Q6DG03" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6DG03", "url": "https://www.uniprot.org/uniprotkb/Q6DG03" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6DG03", "url": "https://www.uniprot.org/uniprotkb/Q6DG03" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6DG03", "url": "https://www.uniprot.org/uniprotkb/Q6DG03" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q6DG03", "url": "https://www.uniprot.org/uniprotkb/Q6DG03" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DG03-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Thr483", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 483, "start_aa": "Thr", "end_pos": 483, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr483", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGA6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGA6", "url": "https://www.uniprot.org/uniprotkb/Q6DGA6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 395, "chemical_mass": 44144.0, "gene_names": "allc;allc;si:ch211-284k10.3;zgc:91799", "protein_name": "Allantoicase", "disease": [], "biological_process": [ { "name": "allantoin catabolic process", "id": "GO:0000256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000256", "evidence": [ { "database": "UniProtKB", "id": "Q6DGA6", "url": "https://www.uniprot.org/uniprotkb/Q6DGA6" } ], "pmid": "" }, { "name": "purine nucleobase metabolic process", "id": "GO:0006144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006144", "evidence": [ { "database": "UniProtKB", "id": "Q6DGA6", "url": "https://www.uniprot.org/uniprotkb/Q6DGA6" } ], "pmid": "" } ], "molecular_function": [ { "name": "allantoicase activity", "id": "GO:0004037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004037", "evidence": [ { "database": "UniProtKB", "id": "Q6DGA6", "url": "https://www.uniprot.org/uniprotkb/Q6DGA6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGI0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 174, "chemical_mass": 20521.0, "gene_names": "rgs8;rgs8;zgc:92913", "protein_name": "Regulator of G protein signaling 8", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" }, { "name": "neuronal cell body membrane", "id": "GO:0032809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032809", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled acetylcholine receptor signaling pathway", "id": "GO:0007213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007213", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" }, { "name": "positive regulation of GTPase activity", "id": "GO:0043547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" }, { "name": "negative regulation of G protein-coupled receptor signaling pathway", "id": "GO:0045744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045744", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" }, { "name": "regulation of dopamine receptor signaling pathway", "id": "GO:0060159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060159", "evidence": [ { "database": "UniProtKB", "id": "Q6DGI0", "url": "https://www.uniprot.org/uniprotkb/Q6DGI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGJ1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGJ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGJ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 139, "chemical_mass": 16326.0, "gene_names": "grifin;grifin;zgc:92897", "protein_name": "Grifin", "disease": [], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q6DGJ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGJ1" } ], "pmid": "" }, { "name": "lactose binding", "id": "GO:0030395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030395", "evidence": [ { "database": "UniProtKB", "id": "Q6DGJ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "Q6DGJ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGK2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGK2", "url": "https://www.uniprot.org/uniprotkb/Q6DGK2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 334, "chemical_mass": 36710.0, "gene_names": "ldhbb;LDH-B-B;ldhbb;zgc:92882", "protein_name": "L-lactate dehydrogenase B-B chain", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6DGK2", "url": "https://www.uniprot.org/uniprotkb/Q6DGK2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DGK2", "url": "https://www.uniprot.org/uniprotkb/Q6DGK2" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-lactate dehydrogenase (NAD+) activity", "id": "GO:0004459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004459", "evidence": [ { "database": "UniProtKB", "id": "Q6DGK2", "url": "https://www.uniprot.org/uniprotkb/Q6DGK2" } ], "pmid": "" } ], "biological_process": [ { "name": "lactate metabolic process", "id": "GO:0006089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006089", "evidence": [ { "database": "UniProtKB", "id": "Q6DGK2", "url": "https://www.uniprot.org/uniprotkb/Q6DGK2" } ], "pmid": "" }, { "name": "pyruvate catabolic process", "id": "GO:0042867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042867", "evidence": [ { "database": "UniProtKB", "id": "Q6DGK2", "url": "https://www.uniprot.org/uniprotkb/Q6DGK2" } ], "pmid": "" }, { "name": "carboxylic acid metabolic process", "id": "GO:0019752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019752", "evidence": [ { "database": "UniProtKB", "id": "Q6DGK2", "url": "https://www.uniprot.org/uniprotkb/Q6DGK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGL7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGL7", "url": "https://www.uniprot.org/uniprotkb/Q6DGL7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 225, "chemical_mass": 25459.0, "gene_names": "tmem147;tmem147;zgc:92863", "protein_name": "BOS complex subunit TMEM147", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL7", "url": "https://www.uniprot.org/uniprotkb/Q6DGL7" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL7", "url": "https://www.uniprot.org/uniprotkb/Q6DGL7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL7", "url": "https://www.uniprot.org/uniprotkb/Q6DGL7" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL7", "url": "https://www.uniprot.org/uniprotkb/Q6DGL7" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to nuclear inner membrane", "id": "GO:0036228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036228", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL7", "url": "https://www.uniprot.org/uniprotkb/Q6DGL7" } ], "pmid": "" }, { "name": "multi-pass transmembrane protein insertion into ER membrane", "id": "GO:0160063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160063", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL7", "url": "https://www.uniprot.org/uniprotkb/Q6DGL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGM2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGM2", "url": "https://www.uniprot.org/uniprotkb/Q6DGM2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 154, "chemical_mass": 16729.0, "gene_names": "sdhda;cybS-A;sdhda;sdhdb;zgc:92857", "protein_name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit A, mitochondrial", "disease": [ { "disease_id": "DOID:0050773", "name": "paraganglioma", "description": "A pheochromocytoma that arises in extraadrenal sympathetic ganglia.", "url": "https://disease-ontology.org/term/DOID:0050773", "evidence": [ { "id": "0050773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050773" } ], "weight": 0.0 }, { "disease_id": "DOID:0060537", "name": "mitochondrial complex II deficiency", "description": "A mitochondrial metabolism disease characterized by a highly variable phenotype. Some patients have multisystem involvement of the brain, heart, muscle, liver, and kidneys resulting in death in infancy, whereas others have only isolated cardiac or muscle involvement with onset in adulthood and normal cognition. It has_material_basis_in homozygous or compound heterozygous mutation in the nuclear-encoded SDHA gene on chromosome 5p, the nuclear-encoded SDHAF1 gene on chromosome 19q, or the nuclear-encoded SDHD gene on chromosome 11q23.", "url": "https://disease-ontology.org/term/DOID:0060537", "evidence": [ { "id": "0060537", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060537" } ], "weight": 0.0 }, { "disease_id": "DOID:0061216", "name": "pheochromocytoma/paraganglioma syndrome 1", "description": "A paraganglioma characterized by the development of neuroendocrine tumors, usually in adulthood that has material_basis_in heterozygous mutation in the SDHD gene.", "url": "https://disease-ontology.org/term/DOID:0061216", "evidence": [ { "id": "0061216", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061216" } ], "weight": 0.0 }, { "disease_id": "DOID:0080533", "name": "Carney-Stratakis syndrome", "description": "A syndrome that is characterized by the presence of multicentric paragangliomas and multifocal gastrointestinal stromal sarcoma tumors.", "url": "https://disease-ontology.org/term/DOID:0080533", "evidence": [ { "id": "0080533", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080533" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q6DGM2", "url": "https://www.uniprot.org/uniprotkb/Q6DGM2" } ], "pmid": "" }, { "name": "respiratory chain complex II (succinate dehydrogenase)", "id": "GO:0045273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045273", "evidence": [ { "database": "UniProtKB", "id": "Q6DGM2", "url": "https://www.uniprot.org/uniprotkb/Q6DGM2" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "Q6DGM2", "url": "https://www.uniprot.org/uniprotkb/Q6DGM2" } ], "pmid": "" }, { "name": "mitochondrial electron transport, succinate to ubiquinone", "id": "GO:0006121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006121", "evidence": [ { "database": "UniProtKB", "id": "Q6DGM2", "url": "https://www.uniprot.org/uniprotkb/Q6DGM2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6DGM2", "url": "https://www.uniprot.org/uniprotkb/Q6DGM2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q6DGM2", "url": "https://www.uniprot.org/uniprotkb/Q6DGM2" } ], "pmid": "" }, { "name": "ubiquinone binding", "id": "GO:0048039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048039", "evidence": [ { "database": "UniProtKB", "id": "Q6DGM2", "url": "https://www.uniprot.org/uniprotkb/Q6DGM2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGQ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ0", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 117, "chemical_mass": 13232.0, "gene_names": "supt4h1;spt4;supt4h1;zgc:92824", "protein_name": "Transcription elongation factor SPT4", "disease": [], "cellular_component": [ { "name": "DSIF complex", "id": "GO:0032044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032044", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ0", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ0", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ0" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ0", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ0", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ0" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ0", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ0" } ], "pmid": "" }, { "name": "transcription elongation-coupled chromatin remodeling", "id": "GO:0140673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140673", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ0", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DGQ0-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Thr88", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 88, "start_aa": "Thr", "end_pos": 88, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr88", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGQ1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 192, "chemical_mass": 21546.0, "gene_names": "nkiras1;nkiras1;si:dkey-126a1.3;zgc:92823", "protein_name": "NF-kappa-B inhibitor-interacting Ras-like protein 1", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ1" } ], "pmid": "" }, { "name": "GTPase activating protein binding", "id": "GO:0032794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032794", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ1" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ1" } ], "pmid": "" }, { "name": "Ral protein signal transduction", "id": "GO:0032484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032484", "evidence": [ { "database": "UniProtKB", "id": "Q6DGQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGT7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 239, "chemical_mass": 27205.0, "gene_names": "nsmce1;nsmce1;zgc:92777", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" }, { "name": "Smc5-Smc6 complex", "id": "GO:0030915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030915", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "Q6DGT7", "url": "https://www.uniprot.org/uniprotkb/Q6DGT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGZ1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 175, "chemical_mass": 19823.0, "gene_names": "b9d2;b9d2;zgc:92713", "protein_name": "B9 domain-containing protein 2", "disease": [ { "disease_id": "DOID:0050777", "name": "Joubert syndrome", "description": "A ciliopathy that is characterized by congenital malformation of the brainstem and agenesis or hypoplasia of the cerebellar vermis leading to an abnormal respiratory pattern, nystagmus, hypotonia, ataxia, and delay in achieving motor milestones.", "url": "https://disease-ontology.org/term/DOID:0050777", "evidence": [ { "id": "0050777", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050777" } ], "weight": 0.0 }, { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" }, { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" }, { "name": "opsin transport", "id": "GO:0036372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036372", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" }, { "name": "establishment of planar polarity", "id": "GO:0001736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001736", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ1", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DGZ3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 202, "chemical_mass": 23643.0, "gene_names": "thoc7;im:7153996;thoc7;wu:fa20e08;wu:fj35e07;zgc:92711", "protein_name": "THO complex subunit 7 homolog", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "pmid": "" }, { "name": "THO complex part of transcription export complex", "id": "GO:0000445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000445", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q6DGZ3", "url": "https://www.uniprot.org/uniprotkb/Q6DGZ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DH02-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DH02", "url": "https://www.uniprot.org/uniprotkb/Q6DH02" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 216, "chemical_mass": 25045.0, "gene_names": "mrpl24;mrpl24;si:ch211-210h11.6;zgc:92702", "protein_name": "Large ribosomal subunit protein uL24m", "disease": [], "cellular_component": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "Q6DH02", "url": "https://www.uniprot.org/uniprotkb/Q6DH02" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6DH02", "url": "https://www.uniprot.org/uniprotkb/Q6DH02" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6DH02", "url": "https://www.uniprot.org/uniprotkb/Q6DH02" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q6DH02", "url": "https://www.uniprot.org/uniprotkb/Q6DH02" } ], "pmid": "" } ], "biological_process": [ { "name": "ATP biosynthetic process", "id": "GO:0006754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006754", "evidence": [ { "database": "UniProtKB", "id": "Q6DH02", "url": "https://www.uniprot.org/uniprotkb/Q6DH02" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q6DH02", "url": "https://www.uniprot.org/uniprotkb/Q6DH02" } ], "pmid": "" }, { "name": "cellular respiration", "id": "GO:0045333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045333", "evidence": [ { "database": "UniProtKB", "id": "Q6DH02", "url": "https://www.uniprot.org/uniprotkb/Q6DH02" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DH42-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 95, "chemical_mass": 10813.0, "gene_names": "eny2;eny2;zgc:92656", "protein_name": "Transcription and mRNA export factor ENY2", "disease": [], "biological_process": [ { "name": "poly(A)+ mRNA export from nucleus", "id": "GO:0016973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016973", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "DUBm complex", "id": "GO:0071819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071819", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "transcription export complex 2", "id": "GO:0070390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070390", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "Q6DH42", "url": "https://www.uniprot.org/uniprotkb/Q6DH42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DH65-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DH65", "url": "https://www.uniprot.org/uniprotkb/Q6DH65" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 208, "chemical_mass": 22804.0, "gene_names": "denr;denr;im:6891640;zgc:113309;zgc:92629", "protein_name": "Density-regulated protein", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "biological_process": [ { "name": "translation reinitiation", "id": "GO:0002188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002188", "evidence": [ { "database": "UniProtKB", "id": "Q6DH65", "url": "https://www.uniprot.org/uniprotkb/Q6DH65" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "Q6DH65", "url": "https://www.uniprot.org/uniprotkb/Q6DH65" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q6DH65", "url": "https://www.uniprot.org/uniprotkb/Q6DH65" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DH65-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Ser9", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6DH65", "url": "https://www.uniprot.org/uniprotkb/Q6DH65" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6DH65", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6DH65" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DH66-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DH66", "url": "https://www.uniprot.org/uniprotkb/Q6DH66" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 146, "chemical_mass": 16292.0, "gene_names": "tomm20b;tomm20b;tomm20;zgc:92628", "protein_name": "Mitochondrial import receptor subunit TOM20 homolog B", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q6DH66", "url": "https://www.uniprot.org/uniprotkb/Q6DH66" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "Q6DH66", "url": "https://www.uniprot.org/uniprotkb/Q6DH66" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "Q6DH66", "url": "https://www.uniprot.org/uniprotkb/Q6DH66" } ], "pmid": "" }, { "name": "tRNA import into mitochondrion", "id": "GO:0016031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016031", "evidence": [ { "database": "UniProtKB", "id": "Q6DH66", "url": "https://www.uniprot.org/uniprotkb/Q6DH66" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial outer membrane translocase complex", "id": "GO:0005742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005742", "evidence": [ { "database": "UniProtKB", "id": "Q6DH66", "url": "https://www.uniprot.org/uniprotkb/Q6DH66" } ], "pmid": "" } ], "molecular_function": [ { "name": "mitochondrion targeting sequence binding", "id": "GO:0030943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030943", "evidence": [ { "database": "UniProtKB", "id": "Q6DH66", "url": "https://www.uniprot.org/uniprotkb/Q6DH66" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DH66-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Ser141", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6DH66", "url": "https://www.uniprot.org/uniprotkb/Q6DH66" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6DH66", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6DH66" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DHB1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHB1", "url": "https://www.uniprot.org/uniprotkb/Q6DHB1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 192, "chemical_mass": 21495.0, "gene_names": "dnal1;dnal1;fc89a04;wu:fc89a04;zgc:92542", "protein_name": "Dynein axonemal light chain 1", "disease": [ { "disease_id": "DOID:0110613", "name": "primary ciliary dyskinesia 16", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with absence of ciliary outer dynein arms, early infantile onset of respiratory distress, and variable occurrence of situs inversus and has_material_basis_in homozygous mutation in the DNAL1 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0110613", "evidence": [ { "id": "0110613", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110613" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q6DHB1", "url": "https://www.uniprot.org/uniprotkb/Q6DHB1" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q6DHB1", "url": "https://www.uniprot.org/uniprotkb/Q6DHB1" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q6DHB1", "url": "https://www.uniprot.org/uniprotkb/Q6DHB1" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "Q6DHB1", "url": "https://www.uniprot.org/uniprotkb/Q6DHB1" } ], "pmid": "" }, { "name": "dynein heavy chain binding", "id": "GO:0045504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045504", "evidence": [ { "database": "UniProtKB", "id": "Q6DHB1", "url": "https://www.uniprot.org/uniprotkb/Q6DHB1" } ], "pmid": "" } ], "biological_process": [ { "name": "outer dynein arm assembly", "id": "GO:0036158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036158", "evidence": [ { "database": "UniProtKB", "id": "Q6DHB1", "url": "https://www.uniprot.org/uniprotkb/Q6DHB1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DHG8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 258, "chemical_mass": 29669.0, "gene_names": "ska1;fc20h04;ska1;wu:fc20h04;zgc:92321", "protein_name": "SKA complex subunit 1", "disease": [], "biological_process": [ { "name": "regulation of microtubule polymerization or depolymerization", "id": "GO:0031110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031110", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "meiotic spindle", "id": "GO:0072687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072687", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG8", "url": "https://www.uniprot.org/uniprotkb/Q6DHG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DHH7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHH7", "url": "https://www.uniprot.org/uniprotkb/Q6DHH7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 190, "chemical_mass": 21322.0, "gene_names": "lzic;lzic;zgc:92310", "protein_name": "Protein LZIC", "disease": [ { "disease_id": "DOID:3347", "name": "osteosarcoma", "description": "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).", "url": "https://disease-ontology.org/term/DOID:3347", "evidence": [ { "id": "3347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3347" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q6DHH7", "url": "https://www.uniprot.org/uniprotkb/Q6DHH7" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q6DHH7", "url": "https://www.uniprot.org/uniprotkb/Q6DHH7" } ], "pmid": "" } ], "molecular_function": [ { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "Q6DHH7", "url": "https://www.uniprot.org/uniprotkb/Q6DHH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DHI0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHI0", "url": "https://www.uniprot.org/uniprotkb/Q6DHI0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 328, "chemical_mass": 36794.0, "gene_names": "acy3.1;acy3.1;si:ch211-217k17.2;zgc:92306", "protein_name": "N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) A", "disease": [], "molecular_function": [ { "name": "aminoacylase activity", "id": "GO:0004046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004046", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI0", "url": "https://www.uniprot.org/uniprotkb/Q6DHI0" } ], "pmid": "" }, { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI0", "url": "https://www.uniprot.org/uniprotkb/Q6DHI0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI0", "url": "https://www.uniprot.org/uniprotkb/Q6DHI0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI0", "url": "https://www.uniprot.org/uniprotkb/Q6DHI0" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI0", "url": "https://www.uniprot.org/uniprotkb/Q6DHI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DHL4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHL4", "url": "https://www.uniprot.org/uniprotkb/Q6DHL4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 96, "chemical_mass": 11029.0, "gene_names": "sumo2;sumo2b;sumo2;zgc:92241", "protein_name": "Small ubiquitin-related modifier 2", "disease": [ { "disease_id": "DOID:0110744", "name": "type 1 diabetes mellitus 5", "description": "A type 1 diabetes mellitus that has_material_basis_in mutation of the SUMO4 gene on chromosome 6q25.1.", "url": "https://disease-ontology.org/term/DOID:0110744", "evidence": [ { "id": "0110744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110744" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DHL4", "url": "https://www.uniprot.org/uniprotkb/Q6DHL4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "Q6DHL4", "url": "https://www.uniprot.org/uniprotkb/Q6DHL4" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "Q6DHL4", "url": "https://www.uniprot.org/uniprotkb/Q6DHL4" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q6DHL4", "url": "https://www.uniprot.org/uniprotkb/Q6DHL4" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "Q6DHL4", "url": "https://www.uniprot.org/uniprotkb/Q6DHL4" } ], "pmid": "" }, { "name": "protein tag activity", "id": "GO:0031386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031386", "evidence": [ { "database": "UniProtKB", "id": "Q6DHL4", "url": "https://www.uniprot.org/uniprotkb/Q6DHL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DHP1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHP1", "url": "https://www.uniprot.org/uniprotkb/Q6DHP1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 212, "chemical_mass": 22366.0, "gene_names": "cldn7a;cldn7a;zgc:92192", "protein_name": "Claudin-7-A", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP1", "url": "https://www.uniprot.org/uniprotkb/Q6DHP1" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP1", "url": "https://www.uniprot.org/uniprotkb/Q6DHP1" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP1", "url": "https://www.uniprot.org/uniprotkb/Q6DHP1" } ], "pmid": "" } ], "biological_process": [ { "name": "head development", "id": "GO:0060322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060322", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP1", "url": "https://www.uniprot.org/uniprotkb/Q6DHP1" } ], "pmid": "" }, { "name": "cell-cell junction organization", "id": "GO:0045216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045216", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP1", "url": "https://www.uniprot.org/uniprotkb/Q6DHP1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DHQ3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 314, "chemical_mass": 35253.0, "gene_names": "acy3.2;acy3.2;id:ibd5047;si:ch211-217k17.4;zgc:92178", "protein_name": "N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) B", "disease": [], "molecular_function": [ { "name": "aminoacylase activity", "id": "GO:0004046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004046", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ3" } ], "pmid": "" }, { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ3" } ], "pmid": "" }, { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides", "id": "GO:0016811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016811", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ3" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DI05-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DI05", "url": "https://www.uniprot.org/uniprotkb/Q6DI05" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 94, "chemical_mass": 10725.0, "gene_names": "sumo3;fc66f10;fl11h12;sumo3b;sumo3;wu:fc66f10;wu:fl11h12;zgc:86902", "protein_name": "Small ubiquitin-related modifier 3", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DI05", "url": "https://www.uniprot.org/uniprotkb/Q6DI05" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DI05", "url": "https://www.uniprot.org/uniprotkb/Q6DI05" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q6DI05", "url": "https://www.uniprot.org/uniprotkb/Q6DI05" } ], "pmid": "" } ], "biological_process": [ { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "Q6DI05", "url": "https://www.uniprot.org/uniprotkb/Q6DI05" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "Q6DI05", "url": "https://www.uniprot.org/uniprotkb/Q6DI05" } ], "pmid": "" }, { "name": "protein tag activity", "id": "GO:0031386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031386", "evidence": [ { "database": "UniProtKB", "id": "Q6DI05", "url": "https://www.uniprot.org/uniprotkb/Q6DI05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DI35-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DI35", "url": "https://www.uniprot.org/uniprotkb/Q6DI35" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 832, "chemical_mass": 94577.0, "gene_names": "tfip11;fd15a02;stip;tfip11;wu:fd15a02;zgc:86644", "protein_name": "Tuftelin-interacting protein 11", "disease": [], "cellular_component": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q6DI35", "url": "https://www.uniprot.org/uniprotkb/Q6DI35" } ], "pmid": "" }, { "name": "U2-type post-mRNA release spliceosomal complex", "id": "GO:0071008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071008", "evidence": [ { "database": "UniProtKB", "id": "Q6DI35", "url": "https://www.uniprot.org/uniprotkb/Q6DI35" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q6DI35", "url": "https://www.uniprot.org/uniprotkb/Q6DI35" } ], "pmid": "" } ], "biological_process": [ { "name": "spliceosomal complex disassembly", "id": "GO:0000390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000390", "evidence": [ { "database": "UniProtKB", "id": "Q6DI35", "url": "https://www.uniprot.org/uniprotkb/Q6DI35" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DI35-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Ser209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6DI35", "url": "https://www.uniprot.org/uniprotkb/Q6DI35" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6DI35", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6DI35" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DI37-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DI37", "url": "https://www.uniprot.org/uniprotkb/Q6DI37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 318, "chemical_mass": 36822.0, "gene_names": "ublcp1;fb33g09;ublcp1;wu:fb33g09;zgc:86634", "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DI37", "url": "https://www.uniprot.org/uniprotkb/Q6DI37" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6DI37", "url": "https://www.uniprot.org/uniprotkb/Q6DI37" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q6DI37", "url": "https://www.uniprot.org/uniprotkb/Q6DI37" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of proteasome assembly", "id": "GO:0090364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090364", "evidence": [ { "database": "UniProtKB", "id": "Q6DI37", "url": "https://www.uniprot.org/uniprotkb/Q6DI37" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DKF0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 626, "chemical_mass": 70735.0, "gene_names": "mxc;mxc;zgc:91988", "protein_name": "Interferon-induced GTP-binding protein MxC", "disease": [ { "disease_id": "DOID:0110197", "name": "Charcot-Marie-Tooth disease dominant intermediate B", "description": "A Charcot-Marie-Tooth disease intermediate type that has_material_basis_in mutation in the gene encoding dynamin-2 (DNM2).", "url": "https://disease-ontology.org/term/DOID:0110197", "evidence": [ { "id": "0110197", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110197" } ], "weight": 0.0 }, { "disease_id": "DOID:0111223", "name": "centronuclear myopathy 1", "description": "An autosomal dominant centronuclear myopathy characterized by slowly progressive muscle wasting and weakness involving mainly the limb girdle, trunk, and neck muscles that has_material_basis_in heterozygous mutation in DNM2 on 19p13.2.", "url": "https://disease-ontology.org/term/DOID:0111223", "evidence": [ { "id": "0111223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111223" } ], "weight": 0.0 }, { "disease_id": "DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood.", "url": "https://disease-ontology.org/term/DOID:0112202", "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ], "weight": 0.0 }, { "disease_id": "DOID:11252", "name": "microcytic anemia", "description": "An anemia that is characterized by a low normal mean corpuscular volume (MCV) (less than 80 fL) and is defined by the presence of small, often hypochromic, red blood cells in a peripheral blood smear.", "url": "https://disease-ontology.org/term/DOID:11252", "evidence": [ { "id": "11252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11252" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "response to exogenous dsRNA", "id": "GO:0043330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043330", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" }, { "name": "synaptic vesicle budding from presynaptic endocytic zone membrane", "id": "GO:0016185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016185", "evidence": [ { "database": "UniProtKB", "id": "Q6DKF0", "url": "https://www.uniprot.org/uniprotkb/Q6DKF0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRC4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRC4", "url": "https://www.uniprot.org/uniprotkb/Q6DRC4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 293, "chemical_mass": 32844.0, "gene_names": "eif3g;eif3g;eif3s4;zgc:56553", "protein_name": "Eukaryotic translation initiation factor 3 subunit G", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6DRC4", "url": "https://www.uniprot.org/uniprotkb/Q6DRC4" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q6DRC4", "url": "https://www.uniprot.org/uniprotkb/Q6DRC4" } ], "pmid": "" } ], "biological_process": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q6DRC4", "url": "https://www.uniprot.org/uniprotkb/Q6DRC4" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q6DRC4", "url": "https://www.uniprot.org/uniprotkb/Q6DRC4" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q6DRC4", "url": "https://www.uniprot.org/uniprotkb/Q6DRC4" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q6DRC4", "url": "https://www.uniprot.org/uniprotkb/Q6DRC4" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q6DRC4", "url": "https://www.uniprot.org/uniprotkb/Q6DRC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRF3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRF3", "url": "https://www.uniprot.org/uniprotkb/Q6DRF3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 237, "chemical_mass": 26101.0, "gene_names": "psmb1;psmb1;wu:fc51f06;zgc:103665", "protein_name": "Proteasome subunit beta type-1", "disease": [ { "disease_id": "DOID:0050696", "name": "fetal alcohol spectrum disorder", "description": "A specific developmental disorder and physical disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of alcohol during pregnancy.", "url": "https://disease-ontology.org/term/DOID:0050696", "evidence": [ { "id": "0050696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050696" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF3", "url": "https://www.uniprot.org/uniprotkb/Q6DRF3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF3", "url": "https://www.uniprot.org/uniprotkb/Q6DRF3" } ], "pmid": "" }, { "name": "proteasome core complex", "id": "GO:0005839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005839", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF3", "url": "https://www.uniprot.org/uniprotkb/Q6DRF3" } ], "pmid": "" } ], "biological_process": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF3", "url": "https://www.uniprot.org/uniprotkb/Q6DRF3" } ], "pmid": "" }, { "name": "cellular response to ethanol", "id": "GO:0071361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071361", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF3", "url": "https://www.uniprot.org/uniprotkb/Q6DRF3" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF3", "url": "https://www.uniprot.org/uniprotkb/Q6DRF3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRF9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRF9", "url": "https://www.uniprot.org/uniprotkb/Q6DRF9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 387, "chemical_mass": 43172.0, "gene_names": "wdr55", "protein_name": "WD repeat-containing protein 55", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF9", "url": "https://www.uniprot.org/uniprotkb/Q6DRF9" } ], "pmid": "" } ], "biological_process": [ { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF9", "url": "https://www.uniprot.org/uniprotkb/Q6DRF9" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF9", "url": "https://www.uniprot.org/uniprotkb/Q6DRF9" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF9", "url": "https://www.uniprot.org/uniprotkb/Q6DRF9" } ], "pmid": "" }, { "name": "chordate pharynx development", "id": "GO:0160093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160093", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF9", "url": "https://www.uniprot.org/uniprotkb/Q6DRF9" } ], "pmid": "" }, { "name": "swim bladder development", "id": "GO:0048794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048794", "evidence": [ { "database": "UniProtKB", "id": "Q6DRF9", "url": "https://www.uniprot.org/uniprotkb/Q6DRF9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRH5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 64, "chemical_mass": 7446.0, "gene_names": "nop10;nola3;nop10;zgc:109956", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "disease": [ { "disease_id": "DOID:0070015", "name": "autosomal recessive dyskeratosis congenita 1", "description": "A dyskeratosis congenita that has_material_basis_in an autosomal recessive mutation of the NOLA3 gene on chromosome 15q14.", "url": "https://disease-ontology.org/term/DOID:0070015", "evidence": [ { "id": "0070015", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070015" } ], "weight": 0.0 }, { "disease_id": "DOID:2729", "name": "dyskeratosis congenita", "description": "A skin disease characterized by cutaneous pigmentation, premature graying, dystrophy of the nails, leukoplakia of the oral mucosa, continuous lacrimation due to atresia of the lacrimal ducts, often thrombocytopenia, anemia, testicular atrophy in the male carriers and predisposition to cancer.", "url": "https://disease-ontology.org/term/DOID:2729", "evidence": [ { "id": "2729", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2729" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" }, { "name": "primitive hemopoiesis", "id": "GO:0060215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060215", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" }, { "name": "rRNA pseudouridine synthesis", "id": "GO:0031118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031118", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" }, { "name": "snRNA pseudouridine synthesis", "id": "GO:0031120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031120", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" }, { "name": "telomere maintenance via telomerase", "id": "GO:0007004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007004", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" } ], "cellular_component": [ { "name": "telomerase holoenzyme complex", "id": "GO:0005697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005697", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" }, { "name": "box H/ACA snoRNP complex", "id": "GO:0031429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031429", "evidence": [ { "database": "UniProtKB", "id": "Q6DRH5", "url": "https://www.uniprot.org/uniprotkb/Q6DRH5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRI4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 112, "chemical_mass": 12755.0, "gene_names": "polr1d;im:7162148;polr1d;zgc:136449", "protein_name": "DNA-directed RNA polymerases I and III subunit RPAC2", "disease": [ { "disease_id": "DOID:0080790", "name": "Treacher Collins syndrome 2", "description": "A Treacher Collins syndrome that has_material_basis_in heterozygous mutation in the POLR1D gene on chromosome 13q12.", "url": "https://disease-ontology.org/term/DOID:0080790", "evidence": [ { "id": "0080790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080790" } ], "weight": 0.0 }, { "disease_id": "DOID:10579", "name": "leukodystrophy", "description": "A cerebral degeneration characterized by dysfunction of the white matter of the brain.", "url": "https://disease-ontology.org/term/DOID:10579", "evidence": [ { "id": "10579", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10579" } ], "weight": 0.0 }, { "disease_id": "DOID:2908", "name": "Treacher Collins syndrome", "description": "A syndrome that is characterized by bilateral and symmetric downslanting palpebral fissures, malar hypoplasia, micrognathia, and external ear abnormalities.", "url": "https://disease-ontology.org/term/DOID:2908", "evidence": [ { "id": "2908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2908" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase I", "id": "GO:0006362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006362", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" }, { "name": "embryonic viscerocranium morphogenesis", "id": "GO:0048703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048703", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA polymerase I complex", "id": "GO:0005736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005736", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI4", "url": "https://www.uniprot.org/uniprotkb/Q6DRI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRI7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 652, "chemical_mass": 72460.0, "gene_names": "ddx51;ddx51;zgc:111800", "protein_name": "ATP-dependent RNA helicase DDX51", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI7", "url": "https://www.uniprot.org/uniprotkb/Q6DRI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DRI7-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Thr128", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 128, "start_aa": "Thr", "end_pos": 128, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr128", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6DRI7-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Thr386", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 386, "start_aa": "Thr", "end_pos": 386, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr386", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRJ7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 632, "chemical_mass": 73217.0, "gene_names": "ndc80;kntc2l;kntc2;ndc80;wu:fb52e02;zgc:111801", "protein_name": "Kinetochore protein NDC80 homolog", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "metaphase chromosome alignment", "id": "GO:0051310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051310", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle spindle assembly checkpoint", "id": "GO:0090267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090267", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "mitotic sister chromatid biorientation", "id": "GO:1990758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990758", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "Ndc80 complex", "id": "GO:0031262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031262", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" }, { "name": "kinetochore adaptor activity", "id": "GO:0140483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140483", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ7", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRJ9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 536, "chemical_mass": 59522.0, "gene_names": "ric8b;fj97c10;ric8b;synbl;wu:fj97c10", "protein_name": "Chaperone Ric-8B", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" }, { "name": "pigment cell development", "id": "GO:0070285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070285", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "Q6DRJ9", "url": "https://www.uniprot.org/uniprotkb/Q6DRJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6DRN3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRN3", "url": "https://www.uniprot.org/uniprotkb/Q6DRN3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 800, "chemical_mass": 92097.0, "gene_names": "noc3l;AD24;c10orf117;cb522;noc3l;sb:cb522", "protein_name": "Nucleolar complex protein 3 homolog", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q6DRN3", "url": "https://www.uniprot.org/uniprotkb/Q6DRN3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DRN3", "url": "https://www.uniprot.org/uniprotkb/Q6DRN3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6DRN3", "url": "https://www.uniprot.org/uniprotkb/Q6DRN3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of lipid metabolic process", "id": "GO:0019216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019216", "evidence": [ { "database": "UniProtKB", "id": "Q6DRN3", "url": "https://www.uniprot.org/uniprotkb/Q6DRN3" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "Q6DRN3", "url": "https://www.uniprot.org/uniprotkb/Q6DRN3" } ], "pmid": "" }, { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "Q6DRN3", "url": "https://www.uniprot.org/uniprotkb/Q6DRN3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DRN3-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Thr253", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 253, "start_aa": "Thr", "end_pos": 253, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr253", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6GMF8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 857, "chemical_mass": 97841.0, "gene_names": "rhbdf1a;rhbdf1;rhbdf1a;rhbdf1;zgc:91984", "protein_name": "Inactive rhomboid protein 1", "disease": [], "biological_process": [ { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" }, { "name": "regulation of protein secretion", "id": "GO:0050708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050708", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" }, { "name": "regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042058", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" }, { "name": "regulation of proteasomal protein catabolic process", "id": "GO:0061136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061136", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" } ], "molecular_function": [ { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "Q6GMF8", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6GMF8-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Thr185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 185, "start_aa": "Thr", "end_pos": 185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr185", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6GMF8-1", "start_pos": "585", "end_pos": "585", "site_lbl": "Asn585", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 585, "start_aa": "Asn", "end_pos": 585, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn585", "evidence": [ { "id": "Q6GMF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6GMF8#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6GMG8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 163, "chemical_mass": 17450.0, "gene_names": "litaf;fb12g04;id:ibd5018;litaf;wu:fb12g04;zgc:91882", "protein_name": "Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog", "disease": [ { "disease_id": "DOID:0110151", "name": "Charcot-Marie-Tooth disease type 1C", "description": "A Charcot-Marie-Tooth disease type 1 that has_material_basis_in heterozygous mutation in the LITAF gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0110151", "evidence": [ { "id": "0110151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110151" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "cytoplasmic side of lysosomal membrane", "id": "GO:0098574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098574", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "cytoplasmic side of late endosome membrane", "id": "GO:0098560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098560", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "cytoplasmic side of early endosome membrane", "id": "GO:0098559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098559", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG8", "url": "https://www.uniprot.org/uniprotkb/Q6GMG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6GMG8-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6GMG8-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Thr7", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6GMH3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 347, "chemical_mass": 39859.0, "gene_names": "twf2;ptk9l;twf1l;twf2;zgc:91817", "protein_name": "Twinfilin-2", "disease": [], "molecular_function": [ { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" }, { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" }, { "name": "regulation of lamellipodium assembly", "id": "GO:0010591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010591", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" }, { "name": "actin filament depolymerization", "id": "GO:0030042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030042", "evidence": [ { "database": "UniProtKB", "id": "Q6GMH3", "url": "https://www.uniprot.org/uniprotkb/Q6GMH3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6GML1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GML1", "url": "https://www.uniprot.org/uniprotkb/Q6GML1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 591, "chemical_mass": 68297.0, "gene_names": "cmah;cmah;zgc:92407", "protein_name": "Cytidine monophosphate-N-acetylneuraminic acid hydroxylase", "disease": [], "biological_process": [ { "name": "N-acetylneuraminate metabolic process", "id": "GO:0006054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006054", "evidence": [ { "database": "UniProtKB", "id": "Q6GML1", "url": "https://www.uniprot.org/uniprotkb/Q6GML1" } ], "pmid": "" }, { "name": "CMP-N-acetylneuraminate metabolic process", "id": "GO:0046381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046381", "evidence": [ { "database": "UniProtKB", "id": "Q6GML1", "url": "https://www.uniprot.org/uniprotkb/Q6GML1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6GML1", "url": "https://www.uniprot.org/uniprotkb/Q6GML1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6GML1", "url": "https://www.uniprot.org/uniprotkb/Q6GML1" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q6GML1", "url": "https://www.uniprot.org/uniprotkb/Q6GML1" } ], "pmid": "" }, { "name": "CMP-N-acetylneuraminate monooxygenase activity", "id": "GO:0030338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030338", "evidence": [ { "database": "UniProtKB", "id": "Q6GML1", "url": "https://www.uniprot.org/uniprotkb/Q6GML1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6GQM0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 234, "chemical_mass": 27149.0, "gene_names": "mreg;mreg;si:ch211-51m24.2;wu:fk68c04;zgc:91968", "protein_name": "Melanoregulin", "disease": [], "biological_process": [ { "name": "phagosome maturation", "id": "GO:0090382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090382", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" }, { "name": "melanosome transport", "id": "GO:0032402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032402", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" }, { "name": "melanosome localization", "id": "GO:0032400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032400", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" }, { "name": "melanosome membrane", "id": "GO:0033162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033162", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "Q6GQM0", "url": "https://www.uniprot.org/uniprotkb/Q6GQM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6GQN8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GQN8", "url": "https://www.uniprot.org/uniprotkb/Q6GQN8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 377, "chemical_mass": 41079.0, "gene_names": "mecr;zgc:110153", "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "disease": [ { "disease_id": "DOID:0081419", "name": "childhood-onset dystonia with optic atrophy and basal ganglia abnormalities", "description": "A dystonia that is characterized by characterized by onset of involuntary movements in the first decade of life and that has_material_basis_in homozygous or compound heterozygous mutation in the MECR gene on chromosome 1p35. Optic atrophy develops around the same time or slightly later.", "url": "https://disease-ontology.org/term/DOID:0081419", "evidence": [ { "id": "0081419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081419" } ], "weight": 0.0 }, { "disease_id": "DOID:0111756", "name": "Leber hereditary optic neuropathy with demyelinating disease of CNS", "description": "A Leber plus disease characterized by Leber hereditary optic neuropathy and demyelination in the central nervous system.", "url": "https://disease-ontology.org/term/DOID:0111756", "evidence": [ { "id": "0111756", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111756" } ], "weight": 0.0 }, { "disease_id": "DOID:5723", "name": "optic atrophy", "description": "An optic nerve disease that is characterized the death of the retinal ganglion cell axons that comprise the optic nerve.", "url": "https://disease-ontology.org/term/DOID:5723", "evidence": [ { "id": "5723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5723" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6GQN8", "url": "https://www.uniprot.org/uniprotkb/Q6GQN8" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "Q6GQN8", "url": "https://www.uniprot.org/uniprotkb/Q6GQN8" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q6GQN8", "url": "https://www.uniprot.org/uniprotkb/Q6GQN8" } ], "pmid": "" } ], "molecular_function": [ { "name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0141148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141148", "evidence": [ { "database": "UniProtKB", "id": "Q6GQN8", "url": "https://www.uniprot.org/uniprotkb/Q6GQN8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6IQ97-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQ97", "url": "https://www.uniprot.org/uniprotkb/Q6IQ97" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 419, "chemical_mass": 46135.0, "gene_names": "rbm4.1;rbm4.1;rbm4;rna-bp4;wu:fc31f07;wu:fc57h11;zgc:56302", "protein_name": "RNA-binding protein 4.1", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ97", "url": "https://www.uniprot.org/uniprotkb/Q6IQ97" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ97", "url": "https://www.uniprot.org/uniprotkb/Q6IQ97" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ97", "url": "https://www.uniprot.org/uniprotkb/Q6IQ97" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ97", "url": "https://www.uniprot.org/uniprotkb/Q6IQ97" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ97", "url": "https://www.uniprot.org/uniprotkb/Q6IQ97" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6IQ97-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Thr364", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 364, "start_aa": "Thr", "end_pos": 364, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr364", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6IQ97-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Ser393", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ97", "url": "https://www.uniprot.org/uniprotkb/Q6IQ97" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6IQ97", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6IQ97" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6IQC7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQC7", "url": "https://www.uniprot.org/uniprotkb/Q6IQC7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 307, "chemical_mass": 35723.0, "gene_names": "tmx2b;fb73h06;si:dkey-28b4.1;tmx2b;tmx2;txndc14;wu:fb73h06;zgc:86830", "protein_name": "Thioredoxin-related transmembrane protein 2-B", "disease": [], "molecular_function": [ { "name": "disulfide oxidoreductase activity", "id": "GO:0015036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015036", "evidence": [ { "database": "UniProtKB", "id": "Q6IQC7", "url": "https://www.uniprot.org/uniprotkb/Q6IQC7" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6IQC7", "url": "https://www.uniprot.org/uniprotkb/Q6IQC7" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "Q6IQC7", "url": "https://www.uniprot.org/uniprotkb/Q6IQC7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6IQC7", "url": "https://www.uniprot.org/uniprotkb/Q6IQC7" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "Q6IQC7", "url": "https://www.uniprot.org/uniprotkb/Q6IQC7" } ], "pmid": "" } ], "biological_process": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q6IQC7", "url": "https://www.uniprot.org/uniprotkb/Q6IQC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6IQE1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQE1", "url": "https://www.uniprot.org/uniprotkb/Q6IQE1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 416, "chemical_mass": 47379.0, "gene_names": "pip4k2c;pip5k2c;pip5k2", "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "1-phosphatidylinositol-5-phosphate 4-kinase activity", "id": "GO:0016309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016309", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE1", "url": "https://www.uniprot.org/uniprotkb/Q6IQE1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE1", "url": "https://www.uniprot.org/uniprotkb/Q6IQE1" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 5-kinase activity", "id": "GO:0016308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016308", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE1", "url": "https://www.uniprot.org/uniprotkb/Q6IQE1" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE1", "url": "https://www.uniprot.org/uniprotkb/Q6IQE1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE1", "url": "https://www.uniprot.org/uniprotkb/Q6IQE1" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE1", "url": "https://www.uniprot.org/uniprotkb/Q6IQE1" } ], "pmid": "" }, { "name": "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process", "id": "GO:1902635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902635", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE1", "url": "https://www.uniprot.org/uniprotkb/Q6IQE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6IQH6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQH6", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 333, "chemical_mass": 36492.0, "gene_names": "plppr1;lppr1;plppr1;sb:cb978;zgc:86759", "protein_name": "Phospholipid phosphatase-related protein type 1", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6IQH6", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q6IQH6", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q6IQH6", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q6IQH6", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "Q6IQH6", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "Q6IQH6", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "Q6IQH6", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6IQH6-1", "start_pos": "162", "end_pos": "162", "site_lbl": "Asn162", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 162, "start_aa": "Asn", "end_pos": 162, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn162", "evidence": [ { "id": "Q6IQH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6IQH6#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6IQM2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQM2", "url": "https://www.uniprot.org/uniprotkb/Q6IQM2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 104, "chemical_mass": 11456.0, "gene_names": "cyc;cycsb;cyc;fk52b01;wu:fk52b01;zgc:86706", "protein_name": "Cytochrome c", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood.", "url": "https://disease-ontology.org/term/DOID:1588", "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q6IQM2", "url": "https://www.uniprot.org/uniprotkb/Q6IQM2" } ], "pmid": "" } ], "molecular_function": [ { "name": "electron transfer activity", "id": "GO:0009055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009055", "evidence": [ { "database": "UniProtKB", "id": "Q6IQM2", "url": "https://www.uniprot.org/uniprotkb/Q6IQM2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6IQM2", "url": "https://www.uniprot.org/uniprotkb/Q6IQM2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q6IQM2", "url": "https://www.uniprot.org/uniprotkb/Q6IQM2" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial electron transport, cytochrome c to oxygen", "id": "GO:0006123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006123", "evidence": [ { "database": "UniProtKB", "id": "Q6IQM2", "url": "https://www.uniprot.org/uniprotkb/Q6IQM2" } ], "pmid": "" }, { "name": "mitochondrial electron transport, ubiquinol to cytochrome c", "id": "GO:0006122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006122", "evidence": [ { "database": "UniProtKB", "id": "Q6IQM2", "url": "https://www.uniprot.org/uniprotkb/Q6IQM2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6IQP3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQP3", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 315, "chemical_mass": 37141.0, "gene_names": "calua;calu;si:ch211-266a5.5;wu:fd50c05;zgc:86677", "protein_name": "Calumenin-A", "disease": [ { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:13207", "name": "proliferative diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:13207", "evidence": [ { "id": "13207", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13207" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q6IQP3", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6IQP3", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q6IQP3", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6IQP3", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "Q6IQP3", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum lumen", "id": "GO:0033018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033018", "evidence": [ { "database": "UniProtKB", "id": "Q6IQP3", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6IQP3", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6IQP3-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Asn131", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 131, "start_aa": "Asn", "end_pos": 131, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn131", "evidence": [ { "id": "Q6IQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6IQP3#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6IQQ7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQQ7", "url": "https://www.uniprot.org/uniprotkb/Q6IQQ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 344, "chemical_mass": 38174.0, "gene_names": "lum;lum;zgc:86661", "protein_name": "Lumican", "disease": [ { "disease_id": "DOID:11830", "name": "myopia", "description": "A refractive error characterized by the inability to see farther objects clearly.", "url": "https://disease-ontology.org/term/DOID:11830", "evidence": [ { "id": "11830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11830" } ], "weight": 0.0 }, { "disease_id": "DOID:14720", "name": "Ehlers-Danlos syndrome classic type 1", "description": "An Ehlers-Danlos syndrome that is characterized by loose-jointedness and fragile, bruisable skin that heals with peculiar 'cigarette-paper' scars and that has_material_basis_in heterozygous mutation in the collagen alpha-1(V) gene (COL5A1) on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:14720", "evidence": [ { "id": "14720", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14720" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 }, { "disease_id": "DOID:5199", "name": "ureteral obstruction", "description": "An urinary tract obstruction that is characterized by a blockage in one or both of the tubes (ureters) that carry urine from the kidneys to the bladder.", "url": "https://disease-ontology.org/term/DOID:5199", "evidence": [ { "id": "5199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5199" } ], "weight": 0.0 }, { "disease_id": "DOID:799", "name": "varicose veins", "description": "A vein disease that is characterized by swollen, twisted veins visible just under the surface of the skin.", "url": "https://disease-ontology.org/term/DOID:799", "evidence": [ { "id": "799", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:799" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6IQQ7", "url": "https://www.uniprot.org/uniprotkb/Q6IQQ7" } ], "pmid": "" } ], "biological_process": [ { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "Q6IQQ7", "url": "https://www.uniprot.org/uniprotkb/Q6IQQ7" } ], "pmid": "" }, { "name": "camera-type eye morphogenesis", "id": "GO:0048593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048593", "evidence": [ { "database": "UniProtKB", "id": "Q6IQQ7", "url": "https://www.uniprot.org/uniprotkb/Q6IQQ7" } ], "pmid": "" }, { "name": "embryonic camera-type eye morphogenesis", "id": "GO:0048596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048596", "evidence": [ { "database": "UniProtKB", "id": "Q6IQQ7", "url": "https://www.uniprot.org/uniprotkb/Q6IQQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6JIY4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6JIY4", "url": "https://www.uniprot.org/uniprotkb/Q6JIY4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 273, "chemical_mass": 30931.0, "gene_names": "hoxc13b", "protein_name": "Homeobox protein Hox-C13b", "disease": [ { "disease_id": "DOID:0111656", "name": "ectodermal dysplasia 9", "description": "A pure hair and nail ectodermal dysplasia that has_material_basis_in homozygous or compound heterozygous mutation in the HOXC13 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0111656", "evidence": [ { "id": "0111656", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111656" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6JIY4", "url": "https://www.uniprot.org/uniprotkb/Q6JIY4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6JIY4", "url": "https://www.uniprot.org/uniprotkb/Q6JIY4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6JIY4", "url": "https://www.uniprot.org/uniprotkb/Q6JIY4" } ], "pmid": "" }, { "name": "fin regeneration", "id": "GO:0031101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031101", "evidence": [ { "database": "UniProtKB", "id": "Q6JIY4", "url": "https://www.uniprot.org/uniprotkb/Q6JIY4" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6JIY4", "url": "https://www.uniprot.org/uniprotkb/Q6JIY4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q6JIY4", "url": "https://www.uniprot.org/uniprotkb/Q6JIY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NUX0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NUX0", "url": "https://www.uniprot.org/uniprotkb/Q6NUX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 558, "chemical_mass": 61154.0, "gene_names": "wfikkn;Gasp2;wfikkn1;wfikkn;zgc:85816", "protein_name": "WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX0", "url": "https://www.uniprot.org/uniprotkb/Q6NUX0" } ], "pmid": "" }, { "name": "receptor antagonist activity", "id": "GO:0048019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048019", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX0", "url": "https://www.uniprot.org/uniprotkb/Q6NUX0" } ], "pmid": "" }, { "name": "transforming growth factor beta binding", "id": "GO:0050431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050431", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX0", "url": "https://www.uniprot.org/uniprotkb/Q6NUX0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX0", "url": "https://www.uniprot.org/uniprotkb/Q6NUX0" } ], "pmid": "" } ], "biological_process": [ { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX0", "url": "https://www.uniprot.org/uniprotkb/Q6NUX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NUX0-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Thr178", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 178, "start_aa": "Thr", "end_pos": 178, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr178", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6NUX0-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Thr184", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 184, "start_aa": "Thr", "end_pos": 184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr184", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6NUX0-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Asn503", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 503, "start_aa": "Asn", "end_pos": 503, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn503", "evidence": [ { "id": "Q6NUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUX0#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NUX8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 193, "chemical_mass": 21893.0, "gene_names": "rhoaa;Rhoa;rhoaa;wu:fa66g04;wu:fb26g07;zgc:66058;zgc:85805", "protein_name": "Rho-related GTP-binding protein RhoA-A", "disease": [ { "disease_id": "DOID:0050665", "name": "fetal alcohol syndrome", "description": "A fetal alcohol spectrum disorder that results in severe mental and physical defects which can develop in a child when the mother drinks alcohol during pregnancy. The presenting features include craniofacial dysmorphology (microcephaly, smooth philtrum, thin upper lip, small eye openings), pre- and postnatal growth deficiency, and central nervous system dysfunction.", "url": "https://disease-ontology.org/term/DOID:0050665", "evidence": [ { "id": "0050665", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050665" } ], "weight": 0.0 }, { "disease_id": "DOID:0080377", "name": "peroxisomal biogenesis disorder", "description": "A peroxisomal biogenesis disorder that has_material_basis_in defects in PEX genes.", "url": "https://disease-ontology.org/term/DOID:0080377", "evidence": [ { "id": "0080377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080377" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:4001", "name": "ovarian carcinoma", "description": "An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:4001", "evidence": [ { "id": "4001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4001" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9408", "name": "acute myocardial infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:9408", "evidence": [ { "id": "9408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9408" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "pmid": "" }, { "name": "skeletal muscle satellite cell migration", "id": "GO:1902766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902766", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "pmid": "" }, { "name": "wound healing, spreading of cells", "id": "GO:0044319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044319", "evidence": [ { "database": "UniProtKB", "id": "Q6NUX8", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NUX8-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Tyr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "Y", "relation": "attached", "comment": "O-linked (GlcNAc) tyrosine;O-GlcNAcylation", "icn3d_view": {}, "start_pos": 34, "start_aa": "Tyr", "end_pos": 34, "end_aa": "Tyr", "residue": "Tyr", "site_lbl": "Tyr34", "evidence": [ { "id": "Q6NUX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUX8#ptm_processing" }, { "id": "26190758", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26190758" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NV18-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NV18", "url": "https://www.uniprot.org/uniprotkb/Q6NV18" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 309, "chemical_mass": 34182.0, "gene_names": "nhej1;nhej1;xlf;zgc:85657", "protein_name": "Non-homologous end-joining factor 1", "disease": [ { "disease_id": "DOID:0061090", "name": "severe combined immunodeficiency 124", "description": "A severe combined immunodeficiency that is characterized by the onset of recurrent infections in infancy or early childhood and that has_material_basis_in homozygous or compound heterozygous mutation in the NHEJ1 gene on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:0061090", "evidence": [ { "id": "0061090", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061090" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nonhomologous end joining complex", "id": "GO:0070419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070419", "evidence": [ { "database": "UniProtKB", "id": "Q6NV18", "url": "https://www.uniprot.org/uniprotkb/Q6NV18" } ], "pmid": "" }, { "name": "DNA ligase IV complex", "id": "GO:0032807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032807", "evidence": [ { "database": "UniProtKB", "id": "Q6NV18", "url": "https://www.uniprot.org/uniprotkb/Q6NV18" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "Q6NV18", "url": "https://www.uniprot.org/uniprotkb/Q6NV18" } ], "pmid": "" } ], "biological_process": [ { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q6NV18", "url": "https://www.uniprot.org/uniprotkb/Q6NV18" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "Q6NV18", "url": "https://www.uniprot.org/uniprotkb/Q6NV18" } ], "pmid": "" }, { "name": "immunoglobulin V(D)J recombination", "id": "GO:0033152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033152", "evidence": [ { "database": "UniProtKB", "id": "Q6NV18", "url": "https://www.uniprot.org/uniprotkb/Q6NV18" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA end binding", "id": "GO:0045027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045027", "evidence": [ { "database": "UniProtKB", "id": "Q6NV18", "url": "https://www.uniprot.org/uniprotkb/Q6NV18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NV24-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NV24", "url": "https://www.uniprot.org/uniprotkb/Q6NV24" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 201, "chemical_mass": 21829.0, "gene_names": "prxl2b;fam213b;prxl2b;sb:cb782;selu3;wu:fc33a02;zgc:85644", "protein_name": "Prostamide/prostaglandin F synthase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NV24", "url": "https://www.uniprot.org/uniprotkb/Q6NV24" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NV24", "url": "https://www.uniprot.org/uniprotkb/Q6NV24" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "Q6NV24", "url": "https://www.uniprot.org/uniprotkb/Q6NV24" } ], "pmid": "" }, { "name": "prostaglandin F synthase activity", "id": "GO:0047017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047017", "evidence": [ { "database": "UniProtKB", "id": "Q6NV24", "url": "https://www.uniprot.org/uniprotkb/Q6NV24" } ], "pmid": "" } ], "biological_process": [ { "name": "prostaglandin biosynthetic process", "id": "GO:0001516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001516", "evidence": [ { "database": "UniProtKB", "id": "Q6NV24", "url": "https://www.uniprot.org/uniprotkb/Q6NV24" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NV31-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 313, "chemical_mass": 35001.0, "gene_names": "wdr82;PTK9L;wdr82;wom;wu:fb22h06;zgc:55453;zgc:85635;zgc:91817", "protein_name": "WD repeat-containing protein 82", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of DNA-templated transcription, elongation", "id": "GO:0032785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032785", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" }, { "name": "DNA-templated transcription termination", "id": "GO:0006353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006353", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" }, { "name": "RNA polymerase II promoter clearance", "id": "GO:0001111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001111", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" }, { "name": "nuclear RNA surveillance", "id": "GO:0071027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071027", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" }, { "name": "lncRNA catabolic process", "id": "GO:0110064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110064", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" }, { "name": "negative regulation of lncRNA transcription", "id": "GO:0140744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140744", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" }, { "name": "PTW/PP1 phosphatase complex", "id": "GO:0072357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072357", "evidence": [ { "database": "UniProtKB", "id": "Q6NV31", "url": "https://www.uniprot.org/uniprotkb/Q6NV31" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NVC5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 619, "chemical_mass": 71198.0, "gene_names": "rhot1a;miro1;rhot1a;rhot1;wu:fd14e11;wu:fi14a05;zgc:55581;zgc:77063", "protein_name": "Mitochondrial Rho GTPase 1-A", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:231", "name": "motor neuron disease", "description": "A neurodegenerative disease that is located_in the motor neurons.", "url": "https://disease-ontology.org/term/DOID:231", "evidence": [ { "id": "231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:231" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitochondrion transport along microtubule", "id": "GO:0047497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047497", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "cellular homeostasis", "id": "GO:0019725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019725", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "mitochondrial outer membrane permeabilization", "id": "GO:0097345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097345", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC5", "url": "https://www.uniprot.org/uniprotkb/Q6NVC5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NW95-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 296, "chemical_mass": 33496.0, "gene_names": "fbxl15;fbxl15;zgc:85882", "protein_name": "F-box/LRR-repeat protein 15", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "pmid": "" } ], "biological_process": [ { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "pmid": "" }, { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q6NW95", "url": "https://www.uniprot.org/uniprotkb/Q6NW95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NWB6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWB6", "url": "https://www.uniprot.org/uniprotkb/Q6NWB6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 135, "chemical_mass": 16061.0, "gene_names": "ucma;GRP1;ucmab;ucma;zgc:85838", "protein_name": "Unique cartilage matrix-associated protein", "disease": [], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q6NWB6", "url": "https://www.uniprot.org/uniprotkb/Q6NWB6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of osteoblast differentiation", "id": "GO:0045667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045667", "evidence": [ { "database": "UniProtKB", "id": "Q6NWB6", "url": "https://www.uniprot.org/uniprotkb/Q6NWB6" } ], "pmid": "" }, { "name": "embryonic skeletal system development", "id": "GO:0048706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048706", "evidence": [ { "database": "UniProtKB", "id": "Q6NWB6", "url": "https://www.uniprot.org/uniprotkb/Q6NWB6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NWE1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWE1", "url": "https://www.uniprot.org/uniprotkb/Q6NWE1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 490, "chemical_mass": 55184.0, "gene_names": "phf10;XAP135;si:dkey-66m17.1;zgc:66233;zgc:85788", "protein_name": "PHD finger protein 10", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1925", "name": "Coffin-Siris syndrome", "description": "An autosomal dominant intellectual developmental disorder that is characterized by mental retardation associated with coarse facial features, hypertrichosis, sparse scalp hair, and hypoplastic or absent fifth fingernails or toenails.", "url": "https://disease-ontology.org/term/DOID:1925", "evidence": [ { "id": "1925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1925" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NWE1", "url": "https://www.uniprot.org/uniprotkb/Q6NWE1" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q6NWE1", "url": "https://www.uniprot.org/uniprotkb/Q6NWE1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q6NWE1", "url": "https://www.uniprot.org/uniprotkb/Q6NWE1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NWE1", "url": "https://www.uniprot.org/uniprotkb/Q6NWE1" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q6NWE1", "url": "https://www.uniprot.org/uniprotkb/Q6NWE1" } ], "pmid": "" } ], "cellular_component": [ { "name": "npBAF complex", "id": "GO:0071564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071564", "evidence": [ { "database": "UniProtKB", "id": "Q6NWE1", "url": "https://www.uniprot.org/uniprotkb/Q6NWE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NWE1-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Thr16", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NWG1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWG1", "url": "https://www.uniprot.org/uniprotkb/Q6NWG1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 314, "chemical_mass": 35904.0, "gene_names": "lrrc59;lrrc59;zgc:85752", "protein_name": "Leucine-rich repeat-containing protein 59", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG1", "url": "https://www.uniprot.org/uniprotkb/Q6NWG1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG1", "url": "https://www.uniprot.org/uniprotkb/Q6NWG1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG1", "url": "https://www.uniprot.org/uniprotkb/Q6NWG1" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG1", "url": "https://www.uniprot.org/uniprotkb/Q6NWG1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NWI4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWI4", "url": "https://www.uniprot.org/uniprotkb/Q6NWI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 119, "chemical_mass": 13615.0, "gene_names": "ypel3;Ypel1;cb475;wu:fi27c07;ypel1;ypel3", "protein_name": "Protein yippee-like 3", "disease": [ { "disease_id": "DOID:0070515", "name": "chromosome 16p11.2 deletion syndrome, 593-kb", "description": "A chromosomal deletion syndrome characterized by language delay and mild intellectual disability that has_material_basis_in partial deletion of a contiguous 593-kb region of chromosome 16p11.2 (chr16:29.5-30.1 Mb).", "url": "https://disease-ontology.org/term/DOID:0070515", "evidence": [ { "id": "0070515", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070515" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6NWI4", "url": "https://www.uniprot.org/uniprotkb/Q6NWI4" } ], "pmid": "" } ], "biological_process": [ { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "Q6NWI4", "url": "https://www.uniprot.org/uniprotkb/Q6NWI4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q6NWI4", "url": "https://www.uniprot.org/uniprotkb/Q6NWI4" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q6NWI4", "url": "https://www.uniprot.org/uniprotkb/Q6NWI4" } ], "pmid": "" }, { "name": "Schwann cell development", "id": "GO:0014044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014044", "evidence": [ { "database": "UniProtKB", "id": "Q6NWI4", "url": "https://www.uniprot.org/uniprotkb/Q6NWI4" } ], "pmid": "" }, { "name": "spinal cord oligodendrocyte cell differentiation", "id": "GO:0021529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021529", "evidence": [ { "database": "UniProtKB", "id": "Q6NWI4", "url": "https://www.uniprot.org/uniprotkb/Q6NWI4" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6NWI4", "url": "https://www.uniprot.org/uniprotkb/Q6NWI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NWJ4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 618, "chemical_mass": 71598.0, "gene_names": "dnajc2;dnajc2;zgc:85671;zrf1", "protein_name": "DnaJ homolog subfamily C member 2", "disease": [], "biological_process": [ { "name": "'de novo' cotranslational protein folding", "id": "GO:0051083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051083", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-modified histone reader activity", "id": "GO:0061649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061649", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NWJ4", "url": "https://www.uniprot.org/uniprotkb/Q6NWJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NWL4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 298, "chemical_mass": 33356.0, "gene_names": "cnot9;cnot9;rcd-1;rcd1;rqcd1;si:dkeyp-84a8.6;wu:fb52b11;wu:fb74e08;zgc:85618", "protein_name": "CCR4-NOT transcription complex subunit 9", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" }, { "name": "CCR4-NOT core complex", "id": "GO:0030015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030015", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" }, { "name": "negative regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033147", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL4", "url": "https://www.uniprot.org/uniprotkb/Q6NWL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NWZ9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NWZ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 201, "chemical_mass": 23474.0, "gene_names": "cdo1;CDO-I;cdo-1;cdo1;cdo;zgc:73181;zgc:77945", "protein_name": "Cysteine dioxygenase type 1", "disease": [ { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NWZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NWZ9" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "Q6NWZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NWZ9" } ], "pmid": "" }, { "name": "nickel cation binding", "id": "GO:0016151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016151", "evidence": [ { "database": "UniProtKB", "id": "Q6NWZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NWZ9" } ], "pmid": "" }, { "name": "cysteine dioxygenase activity", "id": "GO:0017172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017172", "evidence": [ { "database": "UniProtKB", "id": "Q6NWZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NWZ9" } ], "pmid": "" } ], "biological_process": [ { "name": "taurine biosynthetic process", "id": "GO:0042412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042412", "evidence": [ { "database": "UniProtKB", "id": "Q6NWZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NWZ9" } ], "pmid": "" }, { "name": "L-cysteine catabolic process", "id": "GO:0019448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019448", "evidence": [ { "database": "UniProtKB", "id": "Q6NWZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NWZ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NX08-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 422, "chemical_mass": 47281.0, "gene_names": "wdr12;YTM1;fb24f09;wdr12;wu:fb24f09;zgc:55609", "protein_name": "Ribosome biogenesis protein wdr12", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "pmid": "" }, { "name": "PeBoW complex", "id": "GO:0070545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070545", "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000466", "evidence": [ { "database": "UniProtKB", "id": "Q6NX08", "url": "https://www.uniprot.org/uniprotkb/Q6NX08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NX89-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NX89", "url": "https://www.uniprot.org/uniprotkb/Q6NX89" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 155, "chemical_mass": 16879.0, "gene_names": "eif5a;eIF-5A-1;eIF-5A1;eif5a;wu:fb17e01;wu:fb63h04;wu:fk81e04;zgc:77099", "protein_name": "Eukaryotic translation initiation factor 5A-1", "disease": [ { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6NX89", "url": "https://www.uniprot.org/uniprotkb/Q6NX89" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "Q6NX89", "url": "https://www.uniprot.org/uniprotkb/Q6NX89" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q6NX89", "url": "https://www.uniprot.org/uniprotkb/Q6NX89" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q6NX89", "url": "https://www.uniprot.org/uniprotkb/Q6NX89" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NX89", "url": "https://www.uniprot.org/uniprotkb/Q6NX89" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6NX89", "url": "https://www.uniprot.org/uniprotkb/Q6NX89" } ], "pmid": "" } ], "biological_process": [ { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "Q6NX89", "url": "https://www.uniprot.org/uniprotkb/Q6NX89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NXA9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NXA9", "url": "https://www.uniprot.org/uniprotkb/Q6NXA9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 294, "chemical_mass": 33436.0, "gene_names": "ubxn1;fb49a05;saks1;ubxn1;wu:fb49a05;zgc:77531", "protein_name": "UBX domain-containing protein 1", "disease": [], "molecular_function": [ { "name": "K48-linked polyubiquitin modification-dependent protein binding", "id": "GO:0036435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036435", "evidence": [ { "database": "UniProtKB", "id": "Q6NXA9", "url": "https://www.uniprot.org/uniprotkb/Q6NXA9" } ], "pmid": "" }, { "name": "K6-linked polyubiquitin modification-dependent protein binding", "id": "GO:0071796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071796", "evidence": [ { "database": "UniProtKB", "id": "Q6NXA9", "url": "https://www.uniprot.org/uniprotkb/Q6NXA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NXA9", "url": "https://www.uniprot.org/uniprotkb/Q6NXA9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NXA9", "url": "https://www.uniprot.org/uniprotkb/Q6NXA9" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "Q6NXA9", "url": "https://www.uniprot.org/uniprotkb/Q6NXA9" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "Q6NXA9", "url": "https://www.uniprot.org/uniprotkb/Q6NXA9" } ], "pmid": "" }, { "name": "negative regulation of protein K48-linked deubiquitination", "id": "GO:1903094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903094", "evidence": [ { "database": "UniProtKB", "id": "Q6NXA9", "url": "https://www.uniprot.org/uniprotkb/Q6NXA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NXD2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NXD2", "url": "https://www.uniprot.org/uniprotkb/Q6NXD2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 214, "chemical_mass": 24017.0, "gene_names": "chmp2b;chmp2bb;chmp2bl;chmp2b;si:ch211-106g5.3;zgc:77025", "protein_name": "Charged multivesicular body protein 2b", "disease": [ { "disease_id": "DOID:0111227", "name": "frontotemporal dementia and/or amyotrophic lateral sclerosis 7", "description": "A frontotemporal dementia and/or amyotrophic lateral sclerosis that has_material_basis_in heterozygous mutation in CHMP2B on 3p11.2.", "url": "https://disease-ontology.org/term/DOID:0111227", "evidence": [ { "id": "0111227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111227" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:9255", "name": "frontotemporal dementia", "description": "A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language.", "url": "https://disease-ontology.org/term/DOID:9255", "evidence": [ { "id": "9255", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9255" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "Q6NXD2", "url": "https://www.uniprot.org/uniprotkb/Q6NXD2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NXD2", "url": "https://www.uniprot.org/uniprotkb/Q6NXD2" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q6NXD2", "url": "https://www.uniprot.org/uniprotkb/Q6NXD2" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "Q6NXD2", "url": "https://www.uniprot.org/uniprotkb/Q6NXD2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6NXD2", "url": "https://www.uniprot.org/uniprotkb/Q6NXD2" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "Q6NXD2", "url": "https://www.uniprot.org/uniprotkb/Q6NXD2" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "Q6NXD2", "url": "https://www.uniprot.org/uniprotkb/Q6NXD2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NY52-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 684, "chemical_mass": 77833.0, "gene_names": "thoc5;fc54b09;thoc5;wu:fc54b09;zgc:56190;zgc:76912", "protein_name": "THO complex subunit 5 homolog", "disease": [ { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "pmid": "" }, { "name": "THO complex part of transcription export complex", "id": "GO:0000445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000445", "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q6NY52", "url": "https://www.uniprot.org/uniprotkb/Q6NY52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NY64-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 447, "chemical_mass": 51716.0, "gene_names": "ppp2r2d;PP2A-Bdelta;ppp2r2d;si:ch211-136d9.1;zgc:76887", "protein_name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform", "disease": [ { "disease_id": "DOID:1441", "name": "autosomal dominant cerebellar ataxia", "description": "A cerebellar ataxia that has_material_basis_in autosomal dominant inheritance.", "url": "https://disease-ontology.org/term/DOID:1441", "evidence": [ { "id": "1441", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1441" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" }, { "name": "myoblast fusion", "id": "GO:0007520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007520", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" }, { "name": "regulation of chromosome segregation", "id": "GO:0051983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051983", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "Q6NY64", "url": "https://www.uniprot.org/uniprotkb/Q6NY64" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NY77-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NY77", "url": "https://www.uniprot.org/uniprotkb/Q6NY77" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 324, "chemical_mass": 35307.0, "gene_names": "hoga1;zgc:77082", "protein_name": "4-hydroxy-2-oxoglutarate aldolase, mitochondrial", "disease": [ { "disease_id": "DOID:0111672", "name": "primary hyperoxaluria type 3", "description": "A primary hyperoxaluria characterized by recurring calcium oxalate stones that has_material_basis_in homozygous or compound heterozygous mutation in the HOGA1 gene on chromosome 10q24.2.", "url": "https://disease-ontology.org/term/DOID:0111672", "evidence": [ { "id": "0111672", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111672" } ], "weight": 0.0 }, { "disease_id": "DOID:2977", "name": "primary hyperoxaluria", "description": "A carbohydrate metabolic disorder characterized by impaired glyoxylate metabolism resulting in accumulation of oxalate throughout the body typically manifesting as kidney and bladder stones.", "url": "https://disease-ontology.org/term/DOID:2977", "evidence": [ { "id": "2977", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2977" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "(R,S)-4-hydroxy-2-oxoglutarate aldolase activity", "id": "GO:0008700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008700", "evidence": [ { "database": "UniProtKB", "id": "Q6NY77", "url": "https://www.uniprot.org/uniprotkb/Q6NY77" } ], "pmid": "" }, { "name": "(4S)-4-hydroxy-2-oxoglutarate aldolase activity", "id": "GO:0106009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106009", "evidence": [ { "database": "UniProtKB", "id": "Q6NY77", "url": "https://www.uniprot.org/uniprotkb/Q6NY77" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6NY77", "url": "https://www.uniprot.org/uniprotkb/Q6NY77" } ], "pmid": "" } ], "biological_process": [ { "name": "glyoxylate catabolic process", "id": "GO:0009436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009436", "evidence": [ { "database": "UniProtKB", "id": "Q6NY77", "url": "https://www.uniprot.org/uniprotkb/Q6NY77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NY77-1", "start_pos": "277", "end_pos": "277", "site_lbl": "Thr277", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NY82-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NY82", "url": "https://www.uniprot.org/uniprotkb/Q6NY82" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 185, "chemical_mass": 21019.0, "gene_names": "ube2f;ch211-93g23.1;ube2f;zgc:77005", "protein_name": "NEDD8-conjugating enzyme UBE2F", "disease": [], "molecular_function": [ { "name": "NEDD8 conjugating enzyme activity", "id": "GO:0061654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061654", "evidence": [ { "database": "UniProtKB", "id": "Q6NY82", "url": "https://www.uniprot.org/uniprotkb/Q6NY82" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6NY82", "url": "https://www.uniprot.org/uniprotkb/Q6NY82" } ], "pmid": "" }, { "name": "NEDD8 transferase activity", "id": "GO:0019788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019788", "evidence": [ { "database": "UniProtKB", "id": "Q6NY82", "url": "https://www.uniprot.org/uniprotkb/Q6NY82" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NY82", "url": "https://www.uniprot.org/uniprotkb/Q6NY82" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NY82", "url": "https://www.uniprot.org/uniprotkb/Q6NY82" } ], "pmid": "" } ], "biological_process": [ { "name": "protein neddylation", "id": "GO:0045116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045116", "evidence": [ { "database": "UniProtKB", "id": "Q6NY82", "url": "https://www.uniprot.org/uniprotkb/Q6NY82" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NY88-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NY88", "url": "https://www.uniprot.org/uniprotkb/Q6NY88" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 221, "chemical_mass": 24807.0, "gene_names": "chmp3;chmp3;fb47g01;vps24;wu:fb47g01;zgc:76972", "protein_name": "Charged multivesicular body protein 3", "disease": [], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "Q6NY88", "url": "https://www.uniprot.org/uniprotkb/Q6NY88" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NY88", "url": "https://www.uniprot.org/uniprotkb/Q6NY88" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q6NY88", "url": "https://www.uniprot.org/uniprotkb/Q6NY88" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "Q6NY88", "url": "https://www.uniprot.org/uniprotkb/Q6NY88" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6NY88", "url": "https://www.uniprot.org/uniprotkb/Q6NY88" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "Q6NY88", "url": "https://www.uniprot.org/uniprotkb/Q6NY88" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "Q6NY88", "url": "https://www.uniprot.org/uniprotkb/Q6NY88" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NY89-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 640, "chemical_mass": 72897.0, "gene_names": "lsg1;fb99b06;lsg1;wu:fb99b06;zgc:76988", "protein_name": "Large subunit GTPase 1 homolog", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "pmid": "" }, { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "pmid": "" }, { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "Q6NY89", "url": "https://www.uniprot.org/uniprotkb/Q6NY89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NY89-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Thr399", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYA0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYA0", "url": "https://www.uniprot.org/uniprotkb/Q6NYA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 245, "chemical_mass": 27475.0, "gene_names": "srsf1b;sfrs1b;sfrs1;srsf1b;wu:fb80g05;zgc:111894;zgc:65898;zgc:76897", "protein_name": "Serine/arginine-rich splicing factor 1B", "disease": [ { "disease_id": "DOID:0070513", "name": "neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the SRSF1 gene on chromosome 17q22.", "url": "https://disease-ontology.org/term/DOID:0070513", "evidence": [ { "id": "0070513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070513" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4467", "name": "clear cell renal cell carcinoma", "description": "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.", "url": "https://disease-ontology.org/term/DOID:4467", "evidence": [ { "id": "4467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4467" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:633", "name": "myositis", "description": "A myopathy characterized by muscle inflammation.", "url": "https://disease-ontology.org/term/DOID:633", "evidence": [ { "id": "633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:633" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:8692", "name": "myeloid leukemia", "description": "A leukemia that is located_in myeloid tissue.", "url": "https://disease-ontology.org/term/DOID:8692", "evidence": [ { "id": "8692", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8692" } ], "weight": 0.0 }, { "disease_id": "DOID:8991", "name": "cervix uteri carcinoma in situ", "description": "An uterus carcinoma in situ that is located_in the uterine cervix.", "url": "https://disease-ontology.org/term/DOID:8991", "evidence": [ { "id": "8991", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8991" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q6NYA0", "url": "https://www.uniprot.org/uniprotkb/Q6NYA0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NYA0", "url": "https://www.uniprot.org/uniprotkb/Q6NYA0" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q6NYA0", "url": "https://www.uniprot.org/uniprotkb/Q6NYA0" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6NYA0", "url": "https://www.uniprot.org/uniprotkb/Q6NYA0" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q6NYA0", "url": "https://www.uniprot.org/uniprotkb/Q6NYA0" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q6NYA0", "url": "https://www.uniprot.org/uniprotkb/Q6NYA0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYB4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYB4", "url": "https://www.uniprot.org/uniprotkb/Q6NYB4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 359, "chemical_mass": 41035.0, "gene_names": "mab21l1;mab21l1", "protein_name": "Putative nucleotidyltransferase MAB21L1", "disease": [ { "disease_id": "DOID:10629", "name": "microphthalmia", "description": "An eye disease where one or both eyeballs are abnormally small.", "url": "https://disease-ontology.org/term/DOID:10629", "evidence": [ { "id": "10629", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10629" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NYB4", "url": "https://www.uniprot.org/uniprotkb/Q6NYB4" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6NYB4", "url": "https://www.uniprot.org/uniprotkb/Q6NYB4" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q6NYB4", "url": "https://www.uniprot.org/uniprotkb/Q6NYB4" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "Q6NYB4", "url": "https://www.uniprot.org/uniprotkb/Q6NYB4" } ], "pmid": "" } ], "biological_process": [ { "name": "cornea development in camera-type eye", "id": "GO:0061303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061303", "evidence": [ { "database": "UniProtKB", "id": "Q6NYB4", "url": "https://www.uniprot.org/uniprotkb/Q6NYB4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYD1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 80, "chemical_mass": 8381.0, "gene_names": "romo1;romo1;zgc:73345;zgc:77111", "protein_name": "Reactive oxygen species modulator 1", "disease": [ { "disease_id": "DOID:5199", "name": "ureteral obstruction", "description": "An urinary tract obstruction that is characterized by a blockage in one or both of the tubes (ureters) that carry urine from the kidneys to the bladder.", "url": "https://disease-ontology.org/term/DOID:5199", "evidence": [ { "id": "5199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5199" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "pmid": "" }, { "name": "TIM23 mitochondrial import inner membrane translocase complex", "id": "GO:0005744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005744", "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "pmid": "" }, { "name": "positive regulation of reactive oxygen species metabolic process", "id": "GO:2000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000379", "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "pmid": "" }, { "name": "cellular response to reactive oxygen species", "id": "GO:0034614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034614", "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "pmid": "" }, { "name": "replicative senescence", "id": "GO:0090399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090399", "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "Q6NYD1", "url": "https://www.uniprot.org/uniprotkb/Q6NYD1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYK3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYK3", "url": "https://www.uniprot.org/uniprotkb/Q6NYK3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 413, "chemical_mass": 46830.0, "gene_names": "spred2;fb93f08;spred2b;spred2;wu:fb93f08;zgc:77284", "protein_name": "Sprouty-related, EVH1 domain-containing protein 2", "disease": [ { "disease_id": "DOID:3490", "name": "Noonan syndrome", "description": "A RASopathy that is characterized by mildly unusual facial features, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms.", "url": "https://disease-ontology.org/term/DOID:3490", "evidence": [ { "id": "3490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3490" } ], "weight": 0.0 }, { "disease_id": "DOID:4480", "name": "achondroplasia", "description": "An osteochondrodysplasia that is characterized by short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and midface hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, genu varum, and trident hand and that has_material_basis_in heterozygous mutation in the fibroblast growth factor receptor-3 gene (FGFR3) on chromosome 4p16.3. Achondroplasia results in dwarfism due to the abnormal ossification of cartilage in the long bone.", "url": "https://disease-ontology.org/term/DOID:4480", "evidence": [ { "id": "4480", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4480" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK3", "url": "https://www.uniprot.org/uniprotkb/Q6NYK3" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK3", "url": "https://www.uniprot.org/uniprotkb/Q6NYK3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK3", "url": "https://www.uniprot.org/uniprotkb/Q6NYK3" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK3", "url": "https://www.uniprot.org/uniprotkb/Q6NYK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYP8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYP8", "url": "https://www.uniprot.org/uniprotkb/Q6NYP8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 166, "chemical_mass": 18915.0, "gene_names": "eef1akmt1;EEF1AKMT1;N6AMT2;eef1akmt1;n6amt2;zgc:77010", "protein_name": "EEF1A lysine methyltransferase 1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NYP8", "url": "https://www.uniprot.org/uniprotkb/Q6NYP8" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q6NYP8", "url": "https://www.uniprot.org/uniprotkb/Q6NYP8" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "Q6NYP8", "url": "https://www.uniprot.org/uniprotkb/Q6NYP8" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "Q6NYP8", "url": "https://www.uniprot.org/uniprotkb/Q6NYP8" } ], "pmid": "" } ], "biological_process": [ { "name": "peptidyl-lysine methylation", "id": "GO:0018022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018022", "evidence": [ { "database": "UniProtKB", "id": "Q6NYP8", "url": "https://www.uniprot.org/uniprotkb/Q6NYP8" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q6NYP8", "url": "https://www.uniprot.org/uniprotkb/Q6NYP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYR8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYR8", "url": "https://www.uniprot.org/uniprotkb/Q6NYR8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 307, "chemical_mass": 33221.0, "gene_names": "npl;wu:fb53b06;zgc:76930", "protein_name": "N-acetylneuraminate lyase", "disease": [ { "disease_id": "DOID:423", "name": "myopathy", "description": "A muscular disease in which the muscle fibers do not function resulting in muscular weakness.", "url": "https://disease-ontology.org/term/DOID:423", "evidence": [ { "id": "423", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:423" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NYR8", "url": "https://www.uniprot.org/uniprotkb/Q6NYR8" } ], "pmid": "" } ], "biological_process": [ { "name": "N-acetylneuraminate catabolic process", "id": "GO:0019262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019262", "evidence": [ { "database": "UniProtKB", "id": "Q6NYR8", "url": "https://www.uniprot.org/uniprotkb/Q6NYR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "N-acetylneuraminate lyase activity", "id": "GO:0008747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008747", "evidence": [ { "database": "UniProtKB", "id": "Q6NYR8", "url": "https://www.uniprot.org/uniprotkb/Q6NYR8" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "Q6NYR8", "url": "https://www.uniprot.org/uniprotkb/Q6NYR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYT1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYT1", "url": "https://www.uniprot.org/uniprotkb/Q6NYT1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 267, "chemical_mass": 29402.0, "gene_names": "med8;med8;zgc:76877", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NYT1", "url": "https://www.uniprot.org/uniprotkb/Q6NYT1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6NYT1", "url": "https://www.uniprot.org/uniprotkb/Q6NYT1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6NYT1", "url": "https://www.uniprot.org/uniprotkb/Q6NYT1" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6NYT1", "url": "https://www.uniprot.org/uniprotkb/Q6NYT1" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q6NYT1", "url": "https://www.uniprot.org/uniprotkb/Q6NYT1" } ], "pmid": "" } ], "cellular_component": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "Q6NYT1", "url": "https://www.uniprot.org/uniprotkb/Q6NYT1" } ], "pmid": "" }, { "name": "core mediator complex", "id": "GO:0070847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070847", "evidence": [ { "database": "UniProtKB", "id": "Q6NYT1", "url": "https://www.uniprot.org/uniprotkb/Q6NYT1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYZ4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ4", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 456, "chemical_mass": 50476.0, "gene_names": "pla1a;pla1a;wu:fi26h09;zgc:77160", "protein_name": "Phospholipase A1 member A", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ4", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ4", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ4", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipase A1 activity", "id": "GO:0008970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008970", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ4", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4" } ], "pmid": "" }, { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ4", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NYZ4-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Asn276", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 276, "start_aa": "Asn", "end_pos": 276, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn276", "evidence": [ { "id": "Q6NYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NYZ4-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Asn305", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 305, "start_aa": "Asn", "end_pos": 305, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn305", "evidence": [ { "id": "Q6NYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NYZ4-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Asn350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 350, "start_aa": "Asn", "end_pos": 350, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn350", "evidence": [ { "id": "Q6NYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NYZ4-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Asn35", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 35, "start_aa": "Asn", "end_pos": 35, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn35", "evidence": [ { "id": "Q6NYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NYZ4-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Asn36", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 36, "start_aa": "Asn", "end_pos": 36, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn36", "evidence": [ { "id": "Q6NYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NYZ4-1", "start_pos": "72", "end_pos": "72", "site_lbl": "Asn72", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 72, "start_aa": "Asn", "end_pos": 72, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn72", "evidence": [ { "id": "Q6NYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NYZ4-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Asn82", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 82, "start_aa": "Asn", "end_pos": 82, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn82", "evidence": [ { "id": "Q6NYZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ4#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NYZ6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ6", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 469, "chemical_mass": 52458.0, "gene_names": "slc25a25a;scamc2a;slc25a25a;slc25a25;slc25a;wu:fb13d12;wu:fd14e03;zgc:77454", "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A25-A", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ6", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ6", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ6" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ6", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ6" } ], "pmid": "" }, { "name": "ATP transmembrane transporter activity", "id": "GO:0005347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005347", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ6", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ6", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ6" } ], "pmid": "" } ], "biological_process": [ { "name": "ADP transport", "id": "GO:0015866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015866", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ6", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ6" } ], "pmid": "" }, { "name": "ATP transport", "id": "GO:0015867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015867", "evidence": [ { "database": "UniProtKB", "id": "Q6NYZ6", "url": "https://www.uniprot.org/uniprotkb/Q6NYZ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NZ13-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NZ13", "url": "https://www.uniprot.org/uniprotkb/Q6NZ13" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 183, "chemical_mass": 20037.0, "gene_names": "nbl1;dan;nbl1;zgc:77251", "protein_name": "Neuroblastoma suppressor of tumorigenicity 1", "disease": [], "biological_process": [ { "name": "sequestering of BMP from receptor via BMP binding", "id": "GO:0038098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038098", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ13", "url": "https://www.uniprot.org/uniprotkb/Q6NZ13" } ], "pmid": "" }, { "name": "semicircular canal development", "id": "GO:0060872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060872", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ13", "url": "https://www.uniprot.org/uniprotkb/Q6NZ13" } ], "pmid": "" }, { "name": "semicircular canal formation", "id": "GO:0060876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060876", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ13", "url": "https://www.uniprot.org/uniprotkb/Q6NZ13" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ13", "url": "https://www.uniprot.org/uniprotkb/Q6NZ13" } ], "pmid": "" } ], "molecular_function": [ { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ13", "url": "https://www.uniprot.org/uniprotkb/Q6NZ13" } ], "pmid": "" }, { "name": "BMP binding", "id": "GO:0036122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036122", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ13", "url": "https://www.uniprot.org/uniprotkb/Q6NZ13" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NZ21-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NZ21", "url": "https://www.uniprot.org/uniprotkb/Q6NZ21" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 419, "chemical_mass": 47191.0, "gene_names": "rnft1;zgc:77306", "protein_name": "E3 ubiquitin-protein ligase RNFT1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ21", "url": "https://www.uniprot.org/uniprotkb/Q6NZ21" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ21", "url": "https://www.uniprot.org/uniprotkb/Q6NZ21" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ21", "url": "https://www.uniprot.org/uniprotkb/Q6NZ21" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ21", "url": "https://www.uniprot.org/uniprotkb/Q6NZ21" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ21", "url": "https://www.uniprot.org/uniprotkb/Q6NZ21" } ], "pmid": "" }, { "name": "positive regulation of ERAD pathway", "id": "GO:1904294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904294", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ21", "url": "https://www.uniprot.org/uniprotkb/Q6NZ21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NZ22-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 455, "chemical_mass": 52179.0, "gene_names": "mettl14;mettl14;zgc:77296", "protein_name": "N(6)-adenosine-methyltransferase non-catalytic subunit METTL14", "disease": [ { "disease_id": "DOID:0081292", "name": "traumatic brain injury", "description": "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.", "url": "https://disease-ontology.org/term/DOID:0081292", "evidence": [ { "id": "0081292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081292" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA m(6)A methyltransferase activity", "id": "GO:0001734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001734", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" } ], "biological_process": [ { "name": "forebrain radial glial cell differentiation", "id": "GO:0021861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021861", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "mRNA modification", "id": "GO:0016556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016556", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "gliogenesis", "id": "GO:0042063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042063", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "RNA methylation", "id": "GO:0001510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001510", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NZ22", "url": "https://www.uniprot.org/uniprotkb/Q6NZ22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NZS4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NZS4", "url": "https://www.uniprot.org/uniprotkb/Q6NZS4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 505, "chemical_mass": 55338.0, "gene_names": "rtcb;rtcb;zgc:76871", "protein_name": "RNA-splicing ligase RTCB", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6NZS4", "url": "https://www.uniprot.org/uniprotkb/Q6NZS4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6NZS4", "url": "https://www.uniprot.org/uniprotkb/Q6NZS4" } ], "pmid": "" }, { "name": "RNA ligase (GTP) activity", "id": "GO:0170057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170057", "evidence": [ { "database": "UniProtKB", "id": "Q6NZS4", "url": "https://www.uniprot.org/uniprotkb/Q6NZS4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NZS4", "url": "https://www.uniprot.org/uniprotkb/Q6NZS4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NZS4", "url": "https://www.uniprot.org/uniprotkb/Q6NZS4" } ], "pmid": "" }, { "name": "tRNA-splicing ligase complex", "id": "GO:0072669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072669", "evidence": [ { "database": "UniProtKB", "id": "Q6NZS4", "url": "https://www.uniprot.org/uniprotkb/Q6NZS4" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "Q6NZS4", "url": "https://www.uniprot.org/uniprotkb/Q6NZS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NZT6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NZT6", "url": "https://www.uniprot.org/uniprotkb/Q6NZT6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 491, "chemical_mass": 52888.0, "gene_names": "irf2bp2a;CH1073-404G22.1;IRF2BP2;fj35c12;irf2bp2a;irf2bp2b;si:ch1073-404g22.1;wu:fj35c12;zgc:56251", "protein_name": "Interferon regulatory factor 2-binding protein 2-A", "disease": [ { "disease_id": "DOID:0081156", "name": "common variable immunodeficiency 14", "description": "A common variable immunodeficiency that has_material_basis_in heterozygous mutation in the IRF2BP2 gene on chromosome 1q42.", "url": "https://disease-ontology.org/term/DOID:0081156", "evidence": [ { "id": "0081156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081156" } ], "weight": 0.0 }, { "disease_id": "DOID:0081327", "name": "neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures", "description": "A neurodegenerative disease that is characterized by neurodevelopmental regression that became apparent between 2 and 10 years of age after normal early development in most patients, although a few had mild early delays and that has_material_basis_in heterozygous mutation in the IRF2BPL gene on chromosome 14q24.", "url": "https://disease-ontology.org/term/DOID:0081327", "evidence": [ { "id": "0081327", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081327" } ], "weight": 0.0 }, { "disease_id": "DOID:331", "name": "central nervous system disease", "description": "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system.", "url": "https://disease-ontology.org/term/DOID:331", "evidence": [ { "id": "331", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:331" } ], "weight": 0.0 } ], "biological_process": [ { "name": "neutrophil differentiation", "id": "GO:0030223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030223", "evidence": [ { "database": "UniProtKB", "id": "Q6NZT6", "url": "https://www.uniprot.org/uniprotkb/Q6NZT6" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "Q6NZT6", "url": "https://www.uniprot.org/uniprotkb/Q6NZT6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NZT6", "url": "https://www.uniprot.org/uniprotkb/Q6NZT6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6NZT6", "url": "https://www.uniprot.org/uniprotkb/Q6NZT6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NZT6", "url": "https://www.uniprot.org/uniprotkb/Q6NZT6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NZT6", "url": "https://www.uniprot.org/uniprotkb/Q6NZT6" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "Q6NZT6", "url": "https://www.uniprot.org/uniprotkb/Q6NZT6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6NZW8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 186, "chemical_mass": 21494.0, "gene_names": "arl8ba;arl10c;arl8ba;arl8b;fj67a08;wu:fj67a08;zgc:77187", "protein_name": "ADP-ribosylation factor-like protein 8B-A", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "anterograde axonal transport", "id": "GO:0008089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008089", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "late endosome to lysosome transport", "id": "GO:1902774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902774", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "Q6NZW8", "url": "https://www.uniprot.org/uniprotkb/Q6NZW8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P011-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P011", "url": "https://www.uniprot.org/uniprotkb/Q6P011" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 189, "chemical_mass": 20692.0, "gene_names": "emc4;emc4;tmem85;zgc:77852", "protein_name": "ER membrane protein complex subunit 4", "disease": [], "cellular_component": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "Q6P011", "url": "https://www.uniprot.org/uniprotkb/Q6P011" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6P011", "url": "https://www.uniprot.org/uniprotkb/Q6P011" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6P011", "url": "https://www.uniprot.org/uniprotkb/Q6P011" } ], "pmid": "" } ], "biological_process": [ { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "Q6P011", "url": "https://www.uniprot.org/uniprotkb/Q6P011" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "Q6P011", "url": "https://www.uniprot.org/uniprotkb/Q6P011" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0C7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 230, "chemical_mass": 25568.0, "gene_names": "scamp5;scamp5a;scamp5;wu:fc30b07;zgc:77438", "protein_name": "Secretory carrier-associated membrane protein 5", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" }, { "name": "positive regulation of calcium ion-dependent exocytosis", "id": "GO:0045956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045956", "evidence": [ { "database": "UniProtKB", "id": "Q6P0C7", "url": "https://www.uniprot.org/uniprotkb/Q6P0C7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0D1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0D1", "url": "https://www.uniprot.org/uniprotkb/Q6P0D1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 486, "chemical_mass": 53172.0, "gene_names": "slc30a6;slc30a6;zgc:77434;znt6", "protein_name": "Zinc transporter 6", "disease": [], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D1", "url": "https://www.uniprot.org/uniprotkb/Q6P0D1" } ], "pmid": "" } ], "biological_process": [ { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D1", "url": "https://www.uniprot.org/uniprotkb/Q6P0D1" } ], "pmid": "" }, { "name": "zinc ion import into Golgi lumen", "id": "GO:1904257", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904257", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D1", "url": "https://www.uniprot.org/uniprotkb/Q6P0D1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D1", "url": "https://www.uniprot.org/uniprotkb/Q6P0D1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D1", "url": "https://www.uniprot.org/uniprotkb/Q6P0D1" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D1", "url": "https://www.uniprot.org/uniprotkb/Q6P0D1" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D1", "url": "https://www.uniprot.org/uniprotkb/Q6P0D1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P0D1-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Thr403", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 403, "start_aa": "Thr", "end_pos": 403, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr403", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6P0D1-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Thr408", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 408, "start_aa": "Thr", "end_pos": 408, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr408", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0D5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0D5", "url": "https://www.uniprot.org/uniprotkb/Q6P0D5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 640, "chemical_mass": 68823.0, "gene_names": "wbp11;wbp11;zgc:77390", "protein_name": "WW domain-binding protein 11", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D5", "url": "https://www.uniprot.org/uniprotkb/Q6P0D5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D5", "url": "https://www.uniprot.org/uniprotkb/Q6P0D5" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D5", "url": "https://www.uniprot.org/uniprotkb/Q6P0D5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D5", "url": "https://www.uniprot.org/uniprotkb/Q6P0D5" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D5", "url": "https://www.uniprot.org/uniprotkb/Q6P0D5" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D5", "url": "https://www.uniprot.org/uniprotkb/Q6P0D5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P0D5-1", "start_pos": "618", "end_pos": "618", "site_lbl": "Thr618", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 618, "start_aa": "Thr", "end_pos": 618, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr618", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6P0D5-1", "start_pos": "285", "end_pos": "285", "site_lbl": "Ser285", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6P0D5", "url": "https://www.uniprot.org/uniprotkb/Q6P0D5" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6P0D5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P0D5" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0E8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0E8", "url": "https://www.uniprot.org/uniprotkb/Q6P0E8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 287, "chemical_mass": 31668.0, "gene_names": "plpp7;ppapdc3;zgc:77336", "protein_name": "Inactive phospholipid phosphatase 7", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q6P0E8", "url": "https://www.uniprot.org/uniprotkb/Q6P0E8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6P0E8", "url": "https://www.uniprot.org/uniprotkb/Q6P0E8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6P0E8", "url": "https://www.uniprot.org/uniprotkb/Q6P0E8" } ], "pmid": "" } ], "molecular_function": [ { "name": "sphingosine-1-phosphate phosphatase activity", "id": "GO:0042392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042392", "evidence": [ { "database": "UniProtKB", "id": "Q6P0E8", "url": "https://www.uniprot.org/uniprotkb/Q6P0E8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0F0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0F0", "url": "https://www.uniprot.org/uniprotkb/Q6P0F0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 110, "chemical_mass": 12076.0, "gene_names": "emc6;emc6;tmem93;wu:fb02d05;zgc:56250;zgc:77320", "protein_name": "ER membrane protein complex subunit 6", "disease": [], "cellular_component": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F0", "url": "https://www.uniprot.org/uniprotkb/Q6P0F0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F0", "url": "https://www.uniprot.org/uniprotkb/Q6P0F0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F0", "url": "https://www.uniprot.org/uniprotkb/Q6P0F0" } ], "pmid": "" } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F0", "url": "https://www.uniprot.org/uniprotkb/Q6P0F0" } ], "pmid": "" }, { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F0", "url": "https://www.uniprot.org/uniprotkb/Q6P0F0" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F0", "url": "https://www.uniprot.org/uniprotkb/Q6P0F0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0G6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0G6", "url": "https://www.uniprot.org/uniprotkb/Q6P0G6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 190, "chemical_mass": 20932.0, "gene_names": "myl1;fj53a11;myl1;wu:fj53a11;zgc:65785;zgc:77231", "protein_name": "Myosin, light chain 1, alkali;skeletal, fast", "disease": [ { "disease_id": "DOID:0081346", "name": "congenital myopathy 14", "description": "A congenital myopathy that is characterized by onset of severe muscle weakness apparent at birth and sometimes in utero and that has_material_basis_in homozygous mutation in the MYL1 gene on chromosome 2q32. Affected infants have difficulty breathing independently and usually require mechanical ventilation for variable lengths of time.", "url": "https://disease-ontology.org/term/DOID:0081346", "evidence": [ { "id": "0081346", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081346" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6P0G6", "url": "https://www.uniprot.org/uniprotkb/Q6P0G6" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "Q6P0G6", "url": "https://www.uniprot.org/uniprotkb/Q6P0G6" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "Q6P0G6", "url": "https://www.uniprot.org/uniprotkb/Q6P0G6" } ], "pmid": "" } ], "biological_process": [ { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "Q6P0G6", "url": "https://www.uniprot.org/uniprotkb/Q6P0G6" } ], "pmid": "" } ], "cellular_component": [ { "name": "contractile muscle fiber", "id": "GO:0043292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043292", "evidence": [ { "database": "UniProtKB", "id": "Q6P0G6", "url": "https://www.uniprot.org/uniprotkb/Q6P0G6" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "Q6P0G6", "url": "https://www.uniprot.org/uniprotkb/Q6P0G6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0I6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 326, "chemical_mass": 36219.0, "gene_names": "zgc:77398;znf830;ccdc16;zgc:77398;znf830", "protein_name": "Zinc finger protein 830", "disease": [], "biological_process": [ { "name": "mitotic DNA damage checkpoint signaling", "id": "GO:0044773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044773", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" }, { "name": "nuclear DNA replication", "id": "GO:0033260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033260", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I6", "url": "https://www.uniprot.org/uniprotkb/Q6P0I6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0I8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 271, "chemical_mass": 29457.0, "gene_names": "exosc6;exosc6;id:ibd1130;mtr3;wu:fe17d05;zgc:110071;zgc:77314", "protein_name": "Exosome complex component MTR3", "disease": [], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" }, { "name": "exosome (RNase complex)", "id": "GO:0000178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000178", "evidence": [ { "database": "UniProtKB", "id": "Q6P0I8", "url": "https://www.uniprot.org/uniprotkb/Q6P0I8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0U9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0U9", "url": "https://www.uniprot.org/uniprotkb/Q6P0U9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 414, "chemical_mass": 42580.0, "gene_names": "nup42;nup42;nupl2;zgc:77724", "protein_name": "Nucleoporin NUP42", "disease": [], "cellular_component": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "Q6P0U9", "url": "https://www.uniprot.org/uniprotkb/Q6P0U9" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q6P0U9", "url": "https://www.uniprot.org/uniprotkb/Q6P0U9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6P0U9", "url": "https://www.uniprot.org/uniprotkb/Q6P0U9" } ], "pmid": "" }, { "name": "nuclear export signal receptor activity", "id": "GO:0005049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005049", "evidence": [ { "database": "UniProtKB", "id": "Q6P0U9", "url": "https://www.uniprot.org/uniprotkb/Q6P0U9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6P0U9", "url": "https://www.uniprot.org/uniprotkb/Q6P0U9" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "Q6P0U9", "url": "https://www.uniprot.org/uniprotkb/Q6P0U9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P0V6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0V6", "url": "https://www.uniprot.org/uniprotkb/Q6P0V6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 257, "chemical_mass": 28067.0, "gene_names": "rpl8;rpl8;zgc:73105;zgc:77641", "protein_name": "Large ribosomal subunit protein uL2", "disease": [ { "disease_id": "DOID:1339", "name": "Diamond-Blackfan anemia", "description": "A pure red-cell aplasia that is characterized by anemia (low red blood cell counts) with decreased erythroid progenitors in the bone marrow and has_material_basis_insufficient levels of red blood cells due to bone marrow dysfunction.", "url": "https://disease-ontology.org/term/DOID:1339", "evidence": [ { "id": "1339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1339" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6P0V6", "url": "https://www.uniprot.org/uniprotkb/Q6P0V6" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "Q6P0V6", "url": "https://www.uniprot.org/uniprotkb/Q6P0V6" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q6P0V6", "url": "https://www.uniprot.org/uniprotkb/Q6P0V6" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "Q6P0V6", "url": "https://www.uniprot.org/uniprotkb/Q6P0V6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "Q6P0V6", "url": "https://www.uniprot.org/uniprotkb/Q6P0V6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P135-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P135", "url": "https://www.uniprot.org/uniprotkb/Q6P135" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 292, "chemical_mass": 31079.0, "gene_names": "tmub1;tmub1;wu:fa98b10;zgc:77146", "protein_name": "Transmembrane and ubiquitin-like domain-containing protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P135", "url": "https://www.uniprot.org/uniprotkb/Q6P135" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P135", "url": "https://www.uniprot.org/uniprotkb/Q6P135" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6P135", "url": "https://www.uniprot.org/uniprotkb/Q6P135" } ], "pmid": "" } ], "biological_process": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q6P135", "url": "https://www.uniprot.org/uniprotkb/Q6P135" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P135-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Thr130", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P298-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P298", "url": "https://www.uniprot.org/uniprotkb/Q6P298" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 321, "chemical_mass": 34112.0, "gene_names": "nubp1;NUBP1;im:7144207;nubp1;zgc:92138", "protein_name": "Cytosolic Fe-S cluster assembly factor nubp1", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "Q6P298", "url": "https://www.uniprot.org/uniprotkb/Q6P298" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6P298", "url": "https://www.uniprot.org/uniprotkb/Q6P298" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6P298", "url": "https://www.uniprot.org/uniprotkb/Q6P298" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q6P298", "url": "https://www.uniprot.org/uniprotkb/Q6P298" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "Q6P298", "url": "https://www.uniprot.org/uniprotkb/Q6P298" } ], "pmid": "" }, { "name": "ATP-dependent FeS chaperone activity", "id": "GO:0140663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140663", "evidence": [ { "database": "UniProtKB", "id": "Q6P298", "url": "https://www.uniprot.org/uniprotkb/Q6P298" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6P298", "url": "https://www.uniprot.org/uniprotkb/Q6P298" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P2T0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 295, "chemical_mass": 32951.0, "gene_names": "tmem38a;tmem38a;zgc:77831", "protein_name": "Trimeric intracellular cation channel type A", "disease": [], "cellular_component": [ { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051279", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "id": "GO:0014808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014808", "evidence": [ { "database": "UniProtKB", "id": "Q6P2T0", "url": "https://www.uniprot.org/uniprotkb/Q6P2T0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P3H7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 424, "chemical_mass": 47651.0, "gene_names": "rbbp4;rbb4-2;rbb4;rbbp4;wu:fb33a09;wu:fb40e10;zgc:55349;zgc:77854", "protein_name": "Histone-binding protein RBBP4", "disease": [ { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "CAF-1 complex", "id": "GO:0033186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033186", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "NuRD complex", "id": "GO:0016581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016581", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "DNA replication-dependent chromatin assembly", "id": "GO:0006335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006335", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" }, { "name": "fin regeneration", "id": "GO:0031101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031101", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q6P3H7", "url": "https://www.uniprot.org/uniprotkb/Q6P3H7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P4P2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P4P2", "url": "https://www.uniprot.org/uniprotkb/Q6P4P2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 704, "chemical_mass": 82046.0, "gene_names": "lmbrd2b;fk97a10;lmbrd2b;lmbrd2;wu:fk97a10;zgc:73387", "protein_name": "G protein-coupled receptor-associated protein LMBRD2B", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6P4P2", "url": "https://www.uniprot.org/uniprotkb/Q6P4P2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6P4P2", "url": "https://www.uniprot.org/uniprotkb/Q6P4P2" } ], "pmid": "" } ], "biological_process": [ { "name": "adrenergic receptor signaling pathway", "id": "GO:0071875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071875", "evidence": [ { "database": "UniProtKB", "id": "Q6P4P2", "url": "https://www.uniprot.org/uniprotkb/Q6P4P2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P4P2-1", "start_pos": "88", "end_pos": "88", "site_lbl": "Asn88", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 88, "start_aa": "Asn", "end_pos": 88, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn88", "evidence": [ { "id": "Q6P4P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6P4P2#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P4U7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P4U7", "url": "https://www.uniprot.org/uniprotkb/Q6P4U7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 369, "chemical_mass": 41785.0, "gene_names": "tram1;cb289;tcamp;tram1;tram;wu:fb67f10;wu:fc67b03;wu:fi09h09", "protein_name": "Translocating chain-associated membrane protein", "disease": [], "biological_process": [ { "name": "protein insertion into ER membrane", "id": "GO:0045048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045048", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U7", "url": "https://www.uniprot.org/uniprotkb/Q6P4U7" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, translocation", "id": "GO:0006616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006616", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U7", "url": "https://www.uniprot.org/uniprotkb/Q6P4U7" } ], "pmid": "" }, { "name": "determination of heart left/right asymmetry", "id": "GO:0061371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061371", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U7", "url": "https://www.uniprot.org/uniprotkb/Q6P4U7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U7", "url": "https://www.uniprot.org/uniprotkb/Q6P4U7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P5L7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 251, "chemical_mass": 30422.0, "gene_names": "arglu1a;arglu1a;arglu1;si:ch211-149b20.2;wu:fa03a12;zgc:55375;zgc:77695", "protein_name": "Arginine and glutamate-rich protein 1-A", "disease": [], "molecular_function": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q6P5L7", "url": "https://www.uniprot.org/uniprotkb/Q6P5L7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P5M2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 305, "chemical_mass": 33336.0, "gene_names": "skic8;Ski8;skic8;wdr61;zgc:77675", "protein_name": "Superkiller complex protein 8", "disease": [], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "id": "GO:0070478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070478", "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "pmid": "" } ], "cellular_component": [ { "name": "Ski complex", "id": "GO:0055087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055087", "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "pmid": "" }, { "name": "Cdc73/Paf1 complex", "id": "GO:0016593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "evidence": [ { "database": "UniProtKB", "id": "Q6P5M2", "url": "https://www.uniprot.org/uniprotkb/Q6P5M2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P6E6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P6E6", "url": "https://www.uniprot.org/uniprotkb/Q6P6E6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 57, "chemical_mass": 6213.0, "gene_names": "cops9;cops9;myeov2;zgc:77808", "protein_name": "COP9 signalosome complex subunit 9", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P6E6", "url": "https://www.uniprot.org/uniprotkb/Q6P6E6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6P6E6", "url": "https://www.uniprot.org/uniprotkb/Q6P6E6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P6E6", "url": "https://www.uniprot.org/uniprotkb/Q6P6E6" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q6P6E6", "url": "https://www.uniprot.org/uniprotkb/Q6P6E6" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "Q6P6E6", "url": "https://www.uniprot.org/uniprotkb/Q6P6E6" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "Q6P6E6", "url": "https://www.uniprot.org/uniprotkb/Q6P6E6" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "Q6P6E6", "url": "https://www.uniprot.org/uniprotkb/Q6P6E6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6P9Z4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 617, "chemical_mass": 68011.0, "gene_names": "fem1a;fem1a;fi20c04;wu:fi20c04;zgc:63483", "protein_name": "Protein fem-1 homolog A", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" }, { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the C-end degron rule pathway", "id": "GO:0140627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140627", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "Q6P9Z4", "url": "https://www.uniprot.org/uniprotkb/Q6P9Z4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6PBK3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 69, "chemical_mass": 7824.0, "gene_names": "rps28;fb07a10;rps28;wu:fb07a10;wu:fb94f01;zgc:73367", "protein_name": "Small ribosomal subunit protein eS28", "disease": [ { "disease_id": "DOID:0111894", "name": "Diamond-Blackfan anemia 15 with mandibulofacial dysostosis", "description": "A Diamond-Blackfan anemia characterized by Diamond-Blackfan anemia and mandibulofacial dysostosis (micrognathia, downslanting palpebral fissures, submucosal cleft palate or bifid uvula, and malar hypoplasia) that has_material_basis_in heterozygous mutation in the RPS28 gene on chromosome 19p13.2.", "url": "https://disease-ontology.org/term/DOID:0111894", "evidence": [ { "id": "0111894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111894" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" }, { "name": "cytoplasmic side of rough endoplasmic reticulum membrane", "id": "GO:0098556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098556", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q6PBK3", "url": "https://www.uniprot.org/uniprotkb/Q6PBK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6PBP3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PBP3", "url": "https://www.uniprot.org/uniprotkb/Q6PBP3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 212, "chemical_mass": 23043.0, "gene_names": "prxl2a;selenou1a;fam213aa;fam213a;fc08d10;pamm;prxl2a;selenou1a;selenou;selu1;selu;sepu;wu:fb06a02;wu:fc08d10;zgc:73311", "protein_name": "Peroxiredoxin-like 2A", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PBP3", "url": "https://www.uniprot.org/uniprotkb/Q6PBP3" } ], "pmid": "" } ], "molecular_function": [ { "name": "antioxidant activity", "id": "GO:0016209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016209", "evidence": [ { "database": "UniProtKB", "id": "Q6PBP3", "url": "https://www.uniprot.org/uniprotkb/Q6PBP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6PBQ2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 457, "chemical_mass": 50980.0, "gene_names": "chmp7;chmp7;zgc:73300;zgc:77047", "protein_name": "Charged multivesicular body protein 7", "disease": [], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" }, { "name": "vesicle budding from membrane", "id": "GO:0006900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006900", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "Q6PBQ2", "url": "https://www.uniprot.org/uniprotkb/Q6PBQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6PBQ2-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Thr397", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 397, "start_aa": "Thr", "end_pos": 397, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr397", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "Q6PBS3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PBS3", "url": "https://www.uniprot.org/uniprotkb/Q6PBS3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 463, "chemical_mass": 52373.0, "gene_names": "wars;TrpRS;wars1;wars;zgc:73274", "protein_name": "Tryptophan--tRNA ligase, cytoplasmic", "disease": [ { "disease_id": "DOID:0111212", "name": "autosomal dominant distal hereditary motor neuronopathy 9", "description": "An autosomal domiant distal hereditary motor neuronopathy that is characterized by juvenile onset of slowly progressive distal muscle weakness and atrophy affecting both the lower and upper limbs that has_material_basis_in heterozygous mutation in the WARS gene on 14q32.2.", "url": "https://disease-ontology.org/term/DOID:0111212", "evidence": [ { "id": "0111212", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111212" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6PBS3", "url": "https://www.uniprot.org/uniprotkb/Q6PBS3" } ], "pmid": "" }, { "name": "tryptophan-tRNA ligase activity", "id": "GO:0004830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004830", "evidence": [ { "database": "UniProtKB", "id": "Q6PBS3", "url": "https://www.uniprot.org/uniprotkb/Q6PBS3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PBS3", "url": "https://www.uniprot.org/uniprotkb/Q6PBS3" } ], "pmid": "" } ], "biological_process": [ { "name": "embryonic neurocranium morphogenesis", "id": "GO:0048702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048702", "evidence": [ { "database": "UniProtKB", "id": "Q6PBS3", "url": "https://www.uniprot.org/uniprotkb/Q6PBS3" } ], "pmid": "" }, { "name": "tryptophanyl-tRNA aminoacylation", "id": "GO:0006436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006436", "evidence": [ { "database": "UniProtKB", "id": "Q6PBS3", "url": "https://www.uniprot.org/uniprotkb/Q6PBS3" } ], "pmid": "" }, { "name": "auditory receptor cell development", "id": "GO:0060117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060117", "evidence": [ { "database": "UniProtKB", "id": "Q6PBS3", "url": "https://www.uniprot.org/uniprotkb/Q6PBS3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.1" }, { "uniprot_canonical_ac": "E7F1U2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1673, "chemical_mass": 191172.0, "gene_names": "dnmbp;dnmbp;tuba", "protein_name": "Dynamin-binding protein", "disease": [ { "disease_id": "DOID:0070354", "name": "cataract 48", "description": "A cataract that has_material_basis_in homozygous mutation in the DNMBP gene on chromosome 10q24 and is characterized by infantile or early-childhood cataracts and visual impairment.", "url": "https://disease-ontology.org/term/DOID:0070354", "evidence": [ { "id": "0070354", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070354" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E7F1U2", "url": "https://www.uniprot.org/uniprotkb/E7F1U2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7F1U2-1", "start_pos": "716", "end_pos": "716", "site_lbl": "Thr716", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 716, "start_aa": "Thr", "end_pos": 716, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr716", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O73715-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O73715", "url": "https://www.uniprot.org/uniprotkb/O73715" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 374, "chemical_mass": 42715.0, "gene_names": "ldb1a;ldb1b;ldb1a;ldb1;ldb4b;ldb4", "protein_name": "LIM domain-binding protein 1-A", "disease": [ { "disease_id": "DOID:9467", "name": "nail-patella syndrome", "description": "A syndrome characterized by nail dysplasia and absent or hypoplastic patellae that has_material_basis_in heterozygous mutation in the LMX1B gene on chromosome 9q33.3.", "url": "https://disease-ontology.org/term/DOID:9467", "evidence": [ { "id": "9467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9467" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "O73715", "url": "https://www.uniprot.org/uniprotkb/O73715" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "O73715", "url": "https://www.uniprot.org/uniprotkb/O73715" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "O73715", "url": "https://www.uniprot.org/uniprotkb/O73715" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O73715", "url": "https://www.uniprot.org/uniprotkb/O73715" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "O73715", "url": "https://www.uniprot.org/uniprotkb/O73715" } ], "pmid": "" } ], "molecular_function": [ { "name": "LIM domain binding", "id": "GO:0030274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030274", "evidence": [ { "database": "UniProtKB", "id": "O73715", "url": "https://www.uniprot.org/uniprotkb/O73715" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "O73715", "url": "https://www.uniprot.org/uniprotkb/O73715" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O73715-1", "start_pos": "9", "end_pos": "9", "site_lbl": "Thr9", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 9, "start_aa": "Thr", "end_pos": 9, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr9", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8E7C5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1120, "chemical_mass": 126054.0, "gene_names": "inpp5f;hSAC2;im:7143897;inpp5f;sac2;si:dkey-192p21.1", "protein_name": "Phosphatidylinositide 4-phosphatase SAC2", "disease": [], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" }, { "name": "clathrin-coated endocytic vesicle", "id": "GO:0045334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045334", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" }, { "name": "inositol monophosphate 4-phosphatase activity", "id": "GO:0052833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052833", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate phosphatase activity", "id": "GO:0043812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043812", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" } ], "biological_process": [ { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" }, { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" }, { "name": "regulation of endocytic recycling", "id": "GO:2001135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001135", "evidence": [ { "database": "UniProtKB", "id": "A8E7C5", "url": "https://www.uniprot.org/uniprotkb/A8E7C5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LY46-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 757, "chemical_mass": 86847.0, "gene_names": "letm1;KHE;fc31h08;fc58h01;letm1;si:ch211-195n12.1;si:rp71-77d7.1;wu:fc31h08;wu:fc58h01;zgc:109969", "protein_name": "Mitochondrial proton/calcium exchanger protein", "disease": [ { "disease_id": "DOID:0050460", "name": "Wolf-Hirschhorn syndrome", "description": "A chromosomal deletion syndrome that is characterized by distinct craniofacial features, hypotonia and intellectual disability and has_material_basis_in a hemizygous deletion of chromosome 4p16.3.", "url": "https://disease-ontology.org/term/DOID:0050460", "evidence": [ { "id": "0050460", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050460" } ], "weight": 0.0 }, { "disease_id": "DOID:700", "name": "mitochondrial metabolism disease", "description": "An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.", "url": "https://disease-ontology.org/term/DOID:700", "evidence": [ { "id": "700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:700" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" } ], "biological_process": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "potassium ion transport", "id": "GO:0006813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006813", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "mitochondrial calcium ion transmembrane transport", "id": "GO:0006851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006851", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "protein hexamerization", "id": "GO:0034214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034214", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "calcium export from the mitochondrion", "id": "GO:0099093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099093", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "inner mitochondrial membrane organization", "id": "GO:0007007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007007", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" }, { "name": "calcium:proton antiporter activity", "id": "GO:0015369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015369", "evidence": [ { "database": "UniProtKB", "id": "Q1LY46", "url": "https://www.uniprot.org/uniprotkb/Q1LY46" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q7U1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 388, "chemical_mass": 43030.0, "gene_names": "ube3d;ube2cbp;ube3d", "protein_name": "E3 ubiquitin-protein ligase E3D", "disease": [], "biological_process": [ { "name": "regulation of neural retina development", "id": "GO:0061074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061074", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "regulation of melanosome transport", "id": "GO:1902908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902908", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "F1Q7U1", "url": "https://www.uniprot.org/uniprotkb/F1Q7U1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O13166-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 761, "chemical_mass": 82460.0, "gene_names": "tle3a;grg2;gro2;groucho2;sb:eu295;sb:eu753", "protein_name": "Transducin-like enhancer protein 3-A", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" } ], "biological_process": [ { "name": "white fat cell differentiation", "id": "GO:0050872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050872", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" }, { "name": "sclerotome development", "id": "GO:0061056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061056", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" }, { "name": "regulation of retinoic acid biosynthetic process", "id": "GO:1900052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900052", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "O13166", "url": "https://www.uniprot.org/uniprotkb/O13166" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O13166-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Thr302", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 302, "start_aa": "Thr", "end_pos": 302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr302", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "O13166-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Thr334", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 334, "start_aa": "Thr", "end_pos": 334, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr334", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1L8G6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1L8G6", "url": "https://www.uniprot.org/uniprotkb/Q1L8G6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1060, "chemical_mass": 119246.0, "gene_names": "ankib1a;ankib1;ankib1a;ankib1;si:dkey-231l1.6", "protein_name": "Ankyrin repeat and IBR domain-containing protein 1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1L8G6", "url": "https://www.uniprot.org/uniprotkb/Q1L8G6" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "Q1L8G6", "url": "https://www.uniprot.org/uniprotkb/Q1L8G6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q1L8G6", "url": "https://www.uniprot.org/uniprotkb/Q1L8G6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q1L8G6", "url": "https://www.uniprot.org/uniprotkb/Q1L8G6" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "Q1L8G6", "url": "https://www.uniprot.org/uniprotkb/Q1L8G6" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q1L8G6", "url": "https://www.uniprot.org/uniprotkb/Q1L8G6" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q1L8G6", "url": "https://www.uniprot.org/uniprotkb/Q1L8G6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B7ZC77-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 865, "chemical_mass": 95856.0, "gene_names": "Ctnna2;ctnna2;bZ1H10.1;catna2l;ctnna2;im:5410539;si:dkeyp-13b9.1;si:rp71-1h10.1", "protein_name": "Catenin alpha-2", "disease": [ { "disease_id": "DOID:0061138", "name": "complex cortical dysplasia with other brain malformations 9", "description": "A complex cortical dysplasia with other brain malformations characterized by profoundly impaired motor and cognitive development apparent from early infancy that has_material_basis_in homozygous mutation in the CTNNA2 gene on chromosome 2p12.", "url": "https://disease-ontology.org/term/DOID:0061138", "evidence": [ { "id": "0061138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061138" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" } ], "biological_process": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "brain morphogenesis", "id": "GO:0048854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048854", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "regulation of synapse structural plasticity", "id": "GO:0051823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051823", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "B7ZC77", "url": "https://www.uniprot.org/uniprotkb/B7ZC77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9LMC0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 391, "chemical_mass": 44635.0, "gene_names": "dpf3;dpf3;fj43h12;si:ch211-268e23.1;wu:fj43h12", "protein_name": "Zinc finger protein DPF3", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" }, { "name": "cardiac muscle tissue morphogenesis", "id": "GO:0055008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055008", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" }, { "name": "muscle organ morphogenesis", "id": "GO:0048644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048644", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" } ], "cellular_component": [ { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A9LMC0", "url": "https://www.uniprot.org/uniprotkb/A9LMC0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2T929-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 430, "chemical_mass": 47471.0, "gene_names": "rxraa;RXRalpha-B;nr2b1a", "protein_name": "Retinoic acid receptor RXR-alpha-A", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:12935", "name": "alcoholic cardiomyopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:12935", "evidence": [ { "id": "12935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12935" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:8634", "name": "prostate carcinoma in situ", "description": "An in situ carcinoma that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:8634", "evidence": [ { "id": "8634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8634" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "retinoic acid receptor signaling pathway", "id": "GO:0048384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048384", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "nuclear steroid receptor activity", "id": "GO:0003707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003707", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "retinoic acid-responsive element binding", "id": "GO:0044323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044323", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2T929", "url": "https://www.uniprot.org/uniprotkb/A2T929" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BGT0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 491, "chemical_mass": 55643.0, "gene_names": "usp30;si:dkey-72n1.2;usp30", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "protein K6-linked deubiquitination", "id": "GO:0044313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044313", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A2BGT0", "url": "https://www.uniprot.org/uniprotkb/A2BGT0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08CH6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 356, "chemical_mass": 40632.0, "gene_names": "catip;catip;zgc:153063", "protein_name": "Ciliogenesis-associated TTC17-interacting protein", "disease": [ { "disease_id": "DOID:0112335", "name": "spermatogenic failure 54", "description": "A spermatogenic failure characterized by male infertility due to oligoteratoasthenozoospermia, with markedly reduced sperm counts and severely reduced or absent sperm motility that has_material_basis_in homozygous or compound heterozygous mutation in the CATIP gene on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:0112335", "evidence": [ { "id": "0112335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112335" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" }, { "name": "determination of heart left/right asymmetry", "id": "GO:0061371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061371", "evidence": [ { "database": "UniProtKB", "id": "Q08CH6", "url": "https://www.uniprot.org/uniprotkb/Q08CH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FDW2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FDW2", "url": "https://www.uniprot.org/uniprotkb/E7FDW2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1053, "chemical_mass": 118456.0, "gene_names": "pdzrn3b;pdzrn3b;pdzrn3", "protein_name": "E3 ubiquitin-protein ligase PDZRN3-B", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FDW2", "url": "https://www.uniprot.org/uniprotkb/E7FDW2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E7FDW2", "url": "https://www.uniprot.org/uniprotkb/E7FDW2" } ], "pmid": "" } ], "biological_process": [ { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "E7FDW2", "url": "https://www.uniprot.org/uniprotkb/E7FDW2" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E7FDW2", "url": "https://www.uniprot.org/uniprotkb/E7FDW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7FDW2", "url": "https://www.uniprot.org/uniprotkb/E7FDW2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E7FDW2", "url": "https://www.uniprot.org/uniprotkb/E7FDW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7FDW2-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Thr347", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 347, "start_aa": "Thr", "end_pos": 347, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr347", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1RB89-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 500, "chemical_mass": 54894.0, "gene_names": "dync1li2;dync1li2;fc08b04;wu:fc08b04;zgc:112480", "protein_name": "Dynein light intermediate chain", "disease": [], "biological_process": [ { "name": "regulation of metaphase plate congression", "id": "GO:0090235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090235", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle, embryonic", "id": "GO:0009794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009794", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" }, { "name": "dynein heavy chain binding", "id": "GO:0045504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045504", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "F1RB89", "url": "https://www.uniprot.org/uniprotkb/F1RB89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1RB89-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Thr187", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 187, "start_aa": "Thr", "end_pos": 187, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr187", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1RB89-1", "start_pos": "444", "end_pos": "444", "site_lbl": "Thr444", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 444, "start_aa": "Thr", "end_pos": 444, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr444", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F8W2C9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 152, "chemical_mass": 17607.0, "gene_names": "alkal1;alkal1;aug-beta;aug-b;fam150a;si:ch73-98k10.1;si:dkey-30h22.10", "protein_name": "ALK and LTK ligand 1", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" }, { "name": "positive regulation of ERK5 cascade", "id": "GO:0070378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070378", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" }, { "name": "iridophore differentiation", "id": "GO:0050935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050935", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" }, { "name": "receptor signaling protein tyrosine kinase activator activity", "id": "GO:0030298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030298", "evidence": [ { "database": "UniProtKB", "id": "F8W2C9", "url": "https://www.uniprot.org/uniprotkb/F8W2C9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q8W0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 835, "chemical_mass": 97996.0, "gene_names": "cactin;cactin;si:ch211-281o21.6;si:dkey-158a20.4;zgc:158620", "protein_name": "Splicing factor Cactin", "disease": [], "biological_process": [ { "name": "neural retina development", "id": "GO:0003407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003407", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "positive regulation of embryonic development", "id": "GO:0040019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040019", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "anterior/posterior axis specification, embryo", "id": "GO:0008595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008595", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F1Q8W0", "url": "https://www.uniprot.org/uniprotkb/F1Q8W0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0S733-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 452, "chemical_mass": 54096.0, "gene_names": "upf3a;si:dkey-21o13.6;upf3a", "protein_name": "Regulator of nonsense transcripts 3A", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "B0S733", "url": "https://www.uniprot.org/uniprotkb/B0S733" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O13168-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 771, "chemical_mass": 83789.0, "gene_names": "tle3b;GROUCHO1;grg3;gro1;gro3;groucho1;tle3b;wu:fi28a02;wu:fj62f10", "protein_name": "Transducin-like enhancer protein 3-B", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" } ], "pmid": "" }, { "name": "myeloid cell differentiation", "id": "GO:0030099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030099", "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O13168-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Thr306", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "O13168-1", "start_pos": "338", "end_pos": "338", "site_lbl": "Thr338", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 338, "start_aa": "Thr", "end_pos": 338, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr338", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "O13168-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Ser296", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "O13168", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O13168" } ] } ] }, { "uniprot_canonical_ac": "O13168-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Ser299", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "O13168", "url": "https://www.uniprot.org/uniprotkb/O13168" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "O13168", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O13168" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1JPY4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1JPY4", "url": "https://www.uniprot.org/uniprotkb/Q1JPY4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 312, "chemical_mass": 34738.0, "gene_names": "tbpl2;tbp2;tbpl2;trf3", "protein_name": "TATA box-binding protein-like 2", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "biological_process": [ { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "Q1JPY4", "url": "https://www.uniprot.org/uniprotkb/Q1JPY4" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "Q1JPY4", "url": "https://www.uniprot.org/uniprotkb/Q1JPY4" } ], "pmid": "" }, { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "Q1JPY4", "url": "https://www.uniprot.org/uniprotkb/Q1JPY4" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "Q1JPY4", "url": "https://www.uniprot.org/uniprotkb/Q1JPY4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q1JPY4", "url": "https://www.uniprot.org/uniprotkb/Q1JPY4" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "Q1JPY4", "url": "https://www.uniprot.org/uniprotkb/Q1JPY4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1JPY4", "url": "https://www.uniprot.org/uniprotkb/Q1JPY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "C5J7W8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "C5J7W8", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 3640, "chemical_mass": 405061.0, "gene_names": "smg1;atx;smg1;zgc:152973", "protein_name": "Serine/threonine-protein kinase SMG1", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "C5J7W8", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "C5J7W8", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "C5J7W8", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "C5J7W8", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "C5J7W8", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "C5J7W8", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "C5J7W8-1", "start_pos": "1038", "end_pos": "1038", "site_lbl": "Thr1038", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1038, "start_aa": "Thr", "end_pos": 1038, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1038", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "C5J7W8-1", "start_pos": "1883", "end_pos": "1883", "site_lbl": "Thr1883", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1883, "start_aa": "Thr", "end_pos": 1883, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1883", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "C5J7W8-1", "start_pos": "3030", "end_pos": "3030", "site_lbl": "Thr3030", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3030, "start_aa": "Thr", "end_pos": 3030, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3030", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "C5J7W8-1", "start_pos": "384", "end_pos": "384", "site_lbl": "Thr384", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 384, "start_aa": "Thr", "end_pos": 384, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr384", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QWK4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1673, "chemical_mass": 187262.0, "gene_names": "mical3b;MICAL-3B;im:7143388;mical3b;si:dkey-153k10.11;si:dkeyp-27e10.1", "protein_name": "Protein-methionine sulfoxide oxidase mical3b", "disease": [], "molecular_function": [ { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen", "id": "GO:0016709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016709", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "F-actin monooxygenase activity", "id": "GO:0120501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120501", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" }, { "name": "actin filament depolymerization", "id": "GO:0030042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030042", "evidence": [ { "database": "UniProtKB", "id": "F1QWK4", "url": "https://www.uniprot.org/uniprotkb/F1QWK4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QWK4-1", "start_pos": "1185", "end_pos": "1185", "site_lbl": "Thr1185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1185, "start_aa": "Thr", "end_pos": 1185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1185", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QWK4-1", "start_pos": "1236", "end_pos": "1236", "site_lbl": "Thr1236", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1236, "start_aa": "Thr", "end_pos": 1236, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1236", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "L7VG99-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "L7VG99", "url": "https://www.uniprot.org/uniprotkb/L7VG99" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1073, "chemical_mass": 119140.0, "gene_names": "tmem132e;tmem132e", "protein_name": "Transmembrane protein 132E", "disease": [ { "disease_id": "DOID:0111634", "name": "autosomal recessive nonsyndromic deafness 99", "description": "An autosomal recessive nonsyndromic deafness characterized by prelingual, severe to profound sensorineural hearing loss without vestibular dysfunction that has_material_basis_in homozygous or compound heterozygous mutation in the TMEM132E gene on chromosome 17q12.", "url": "https://disease-ontology.org/term/DOID:0111634", "evidence": [ { "id": "0111634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111634" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "L7VG99", "url": "https://www.uniprot.org/uniprotkb/L7VG99" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of mechanical stimulus involved in sensory perception of sound", "id": "GO:0050910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050910", "evidence": [ { "database": "UniProtKB", "id": "L7VG99", "url": "https://www.uniprot.org/uniprotkb/L7VG99" } ], "pmid": "" }, { "name": "posterior lateral line neuromast hair cell development", "id": "GO:0035677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035677", "evidence": [ { "database": "UniProtKB", "id": "L7VG99", "url": "https://www.uniprot.org/uniprotkb/L7VG99" } ], "pmid": "" }, { "name": "auditory receptor cell development", "id": "GO:0060117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060117", "evidence": [ { "database": "UniProtKB", "id": "L7VG99", "url": "https://www.uniprot.org/uniprotkb/L7VG99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "L7VG99-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Asn102", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 102, "start_aa": "Asn", "end_pos": 102, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn102", "evidence": [ { "id": "L7VG99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/L7VG99#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "L7VG99-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Thr31", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr31", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "L7VG99-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Asn324", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 324, "start_aa": "Asn", "end_pos": 324, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn324", "evidence": [ { "id": "L7VG99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/L7VG99#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "L7VG99-1", "start_pos": "396", "end_pos": "396", "site_lbl": "Asn396", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 396, "start_aa": "Asn", "end_pos": 396, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn396", "evidence": [ { "id": "L7VG99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/L7VG99#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "L7VG99-1", "start_pos": "746", "end_pos": "746", "site_lbl": "Asn746", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 746, "start_aa": "Asn", "end_pos": 746, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn746", "evidence": [ { "id": "L7VG99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/L7VG99#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LUA6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LUA6", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 3028, "chemical_mass": 342362.0, "gene_names": "trioa;trio;si:ch211-13c6.1;si:dkey-158b13.2;trio", "protein_name": "Triple functional domain protein", "disease": [ { "disease_id": "DOID:0061036", "name": "autosomal dominant intellectual developmental disorder 63 with macrocephaly", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the TRIO gene on chromosome 5p15.", "url": "https://disease-ontology.org/term/DOID:0061036", "evidence": [ { "id": "0061036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061036" } ], "weight": 0.0 }, { "disease_id": "DOID:0070074", "name": "autosomal dominant intellectual developmental disorder 44", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the TRIO gene on chromosome 5p15.2.", "url": "https://disease-ontology.org/term/DOID:0070074", "evidence": [ { "id": "0070074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070074" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q1LUA6", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q1LUA6", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q1LUA6", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q1LUA6", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1LUA6", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ], "pmid": "" }, { "name": "extrinsic component of membrane", "id": "GO:0019898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019898", "evidence": [ { "database": "UniProtKB", "id": "Q1LUA6", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ], "pmid": "" } ], "biological_process": [ { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q1LUA6", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1LUA6-1", "start_pos": "2388", "end_pos": "2388", "site_lbl": "Thr2388", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2388, "start_aa": "Thr", "end_pos": 2388, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2388", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P61799-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 324, "chemical_mass": 36522.0, "gene_names": "aptx;FHA-HIT;aptx", "protein_name": "Aprataxin", "disease": [ { "disease_id": "DOID:0050754", "name": "early-onset ataxia with oculomotor apraxia and hypoalbuminemia", "description": "An autosomal recessive cerebellar ataxia that is characterized by progressive cerebellar ataxia including oculomotor apraxia, severe neuropathy and hypoalbuminemia, has_material_basis_in autosomal recessive inheritance of mutation in the APTX gene.", "url": "https://disease-ontology.org/term/DOID:0050754", "evidence": [ { "id": "0050754", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050754" } ], "weight": 0.0 }, { "disease_id": "DOID:14784", "name": "olivopontocerebellar atrophy", "description": "A neurodegenerative disease that is characterized by progressive cerebellar ataxia, leading to clumsiness in body movements, veering from midline when walking, wide-based stance, and falls without signs of paralysis or weakness and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in degeneration of neuron in the cerebellum, pons and inferior olives.", "url": "https://disease-ontology.org/term/DOID:14784", "evidence": [ { "id": "14784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14784" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "DNA 5'-adenosine monophosphate hydrolase activity", "id": "GO:0033699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033699", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "mismatched DNA binding", "id": "GO:0030983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030983", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "single-strand break-containing DNA binding", "id": "GO:1990165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990165", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "DNA-3'-diphospho-5'-guanosine diphosphatase activity", "id": "GO:0120108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120108", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" } ], "biological_process": [ { "name": "single strand break repair", "id": "GO:0000012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000012", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P61799", "url": "https://www.uniprot.org/uniprotkb/P61799" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F4Z4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 578, "chemical_mass": 63372.0, "gene_names": "zdhhc1;dhhc1;zdhhc1", "protein_name": "Palmitoyltransferase ZDHHC1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" }, { "name": "positive regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900227", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "E7F4Z4", "url": "https://www.uniprot.org/uniprotkb/E7F4Z4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QQN9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 369, "chemical_mass": 42256.0, "gene_names": "septin2;nedd5;sept2;septin2;wu:fb52g01;wu:fb99a01", "protein_name": "Septin", "disease": [], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "F1QQN9", "url": "https://www.uniprot.org/uniprotkb/F1QQN9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IFW2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1909, "chemical_mass": 213454.0, "gene_names": "ptprfb;ptprf;fj23e12;lar;ptprfb;ptprf;si:dkey-21k10.1;wu:fj23e12", "protein_name": "Receptor-type tyrosine-protein phosphatase F", "disease": [ { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 }, { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "pmid": "" }, { "name": "synaptic membrane adhesion", "id": "GO:0099560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099560", "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "pmid": "" }, { "name": "sensory neuron axon guidance", "id": "GO:0097374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097374", "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A4IFW2", "url": "https://www.uniprot.org/uniprotkb/A4IFW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A4IFW2-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Asn119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 119, "start_aa": "Asn", "end_pos": 119, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn119", "evidence": [ { "id": "A4IFW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFW2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4IFW2-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Asn251", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 251, "start_aa": "Asn", "end_pos": 251, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn251", "evidence": [ { "id": "A4IFW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFW2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4IFW2-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Asn296", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 296, "start_aa": "Asn", "end_pos": 296, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn296", "evidence": [ { "id": "A4IFW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFW2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4IFW2-1", "start_pos": "721", "end_pos": "721", "site_lbl": "Asn721", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 721, "start_aa": "Asn", "end_pos": 721, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn721", "evidence": [ { "id": "A4IFW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFW2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4IFW2-1", "start_pos": "963", "end_pos": "963", "site_lbl": "Asn963", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 963, "start_aa": "Asn", "end_pos": 963, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn963", "evidence": [ { "id": "A4IFW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFW2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4IFW2-1", "start_pos": "966", "end_pos": "966", "site_lbl": "Asn966", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 966, "start_aa": "Asn", "end_pos": 966, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn966", "evidence": [ { "id": "A4IFW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFW2#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QE38-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 831, "chemical_mass": 92911.0, "gene_names": "ptpra;RPTP[a];ptpra", "protein_name": "Receptor-type tyrosine-protein phosphatase alpha", "disease": [ { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "pmid": "" } ], "biological_process": [ { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "pmid": "" }, { "name": "regulation of protein kinase activity", "id": "GO:0045859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045859", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "pmid": "" }, { "name": "convergent extension involved in gastrulation", "id": "GO:0060027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060027", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "pmid": "" }, { "name": "fin regeneration", "id": "GO:0031101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031101", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QE38-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QE38-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Thr114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 114, "start_aa": "Thr", "end_pos": 114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr114", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QE38-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Thr140", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 140, "start_aa": "Thr", "end_pos": 140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr140", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QE38-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Thr66", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QE38-1", "start_pos": "827", "end_pos": "827", "site_lbl": "Tyr827", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "F1QE38", "url": "https://www.uniprot.org/uniprotkb/F1QE38" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q29RA5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 256, "chemical_mass": 28180.0, "gene_names": "tigara;c12orf5a;tigara;zgc:136900", "protein_name": "Probable fructose-2,6-bisphosphatase TIGAR A", "disease": [], "biological_process": [ { "name": "regulation of pentose-phosphate shunt", "id": "GO:0043456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043456", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" }, { "name": "negative regulation of glycolytic process", "id": "GO:0045820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045820", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" } ], "molecular_function": [ { "name": "fructose-2,6-bisphosphate 2-phosphatase activity", "id": "GO:0004331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004331", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q29RA5", "url": "https://www.uniprot.org/uniprotkb/Q29RA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QH17-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1994, "chemical_mass": 222811.0, "gene_names": "mical3a;mical3a;si:dkeyp-122e2.1", "protein_name": "Protein-methionine sulfoxide oxidase mical3a", "disease": [], "molecular_function": [ { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen", "id": "GO:0016709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016709", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "F-actin monooxygenase activity", "id": "GO:0120501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120501", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" }, { "name": "actin filament depolymerization", "id": "GO:0030042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030042", "evidence": [ { "database": "UniProtKB", "id": "F1QH17", "url": "https://www.uniprot.org/uniprotkb/F1QH17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QH17-1", "start_pos": "1454", "end_pos": "1454", "site_lbl": "Thr1454", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1454, "start_aa": "Thr", "end_pos": 1454, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1454", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QH17-1", "start_pos": "1721", "end_pos": "1721", "site_lbl": "Thr1721", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1721, "start_aa": "Thr", "end_pos": 1721, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1721", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7EXX2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 544, "chemical_mass": 58779.0, "gene_names": "slc41a1;fd54c09;slc41a1;wu:fd54c09", "protein_name": "Solute carrier family 41 member 1", "disease": [ { "disease_id": "DOID:12712", "name": "nephronophthisis", "description": "A kidney disease that is characterized by a chronic tubulointerstitial nephritis that progress to terminal renal failure during the second decade (juvenile form) or before the age of 5 years (infantile form) resulting from dysfunction of ciliary proteins (ciliopathy).", "url": "https://disease-ontology.org/term/DOID:12712", "evidence": [ { "id": "12712", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12712" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium:sodium antiporter activity", "id": "GO:0061768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061768", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transporter activity", "id": "GO:0008324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008324", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" } ], "biological_process": [ { "name": "magnesium ion homeostasis", "id": "GO:0010960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010960", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" }, { "name": "pronephros development", "id": "GO:0048793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048793", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" }, { "name": "metal ion transport", "id": "GO:0030001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030001", "evidence": [ { "database": "UniProtKB", "id": "E7EXX2", "url": "https://www.uniprot.org/uniprotkb/E7EXX2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08CJ7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08CJ7", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 523, "chemical_mass": 59499.0, "gene_names": "arsk;arsk;zgc:153019", "protein_name": "Arylsulfatase K", "disease": [ { "disease_id": "DOID:0061128", "name": "mucopolysaccharidosis X", "description": "A mucopolysaccharidos characterized by childhood-onset disorder associated with disproportionate short-trunk short stature and skeletal, cardiac, and ophthalmologic abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the ARSK gene, which encodes arylsulfatase K, on chromosome 5q15.", "url": "https://disease-ontology.org/term/DOID:0061128", "evidence": [ { "id": "0061128", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061128" } ], "weight": 0.0 }, { "disease_id": "DOID:12798", "name": "mucopolysaccharidosis", "description": "A lysosomal storage disease that involves the accumulation of glycosaminoglycans in the tissues and their excretion in the urine.", "url": "https://disease-ontology.org/term/DOID:12798", "evidence": [ { "id": "12798", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12798" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q08CJ7", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q08CJ7", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q08CJ7", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7" } ], "pmid": "" }, { "name": "arylsulfatase activity", "id": "GO:0004065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004065", "evidence": [ { "database": "UniProtKB", "id": "Q08CJ7", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7" } ], "pmid": "" }, { "name": "glucuronate-2-sulfatase activity", "id": "GO:0015024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015024", "evidence": [ { "database": "UniProtKB", "id": "Q08CJ7", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08CJ7-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Asn103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 103, "start_aa": "Asn", "end_pos": 103, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn103", "evidence": [ { "id": "Q08CJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CJ7-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Thr213", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q08CJ7-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Asn257", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 257, "start_aa": "Asn", "end_pos": 257, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn257", "evidence": [ { "id": "Q08CJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CJ7-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Asn405", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 405, "start_aa": "Asn", "end_pos": 405, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn405", "evidence": [ { "id": "Q08CJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CJ7#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B6ZK76-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 701, "chemical_mass": 79647.0, "gene_names": "il1rapl1a;fi18g04;il1rapl1a;wu:fi18g04;zgc:152866", "protein_name": "Interleukin-1 receptor accessory protein-like 1-A", "disease": [ { "disease_id": "DOID:0112022", "name": "non-syndromic X-linked intellectual disability 21", "description": "A non-syndromic X-linked intellectual disability characterized by a spectrum of cognitive neurologic impairments ranging from moderate mental retardation to high-functioning autism that has_material_basis_in hemizygous mutation in the IL1RAPL1 gene on chromosome Xp21.3-p21.2.", "url": "https://disease-ontology.org/term/DOID:0112022", "evidence": [ { "id": "0112022", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112022" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" }, { "name": "negative regulation of exocytosis", "id": "GO:0045920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045920", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" } ], "molecular_function": [ { "name": "interleukin-1 receptor activity", "id": "GO:0004908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004908", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" }, { "name": "NAD+ nucleosidase activity, cyclic ADP-ribose generating", "id": "GO:0061809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061809", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "B6ZK76", "url": "https://www.uniprot.org/uniprotkb/B6ZK76" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B6ZK76-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Asn125", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 125, "start_aa": "Asn", "end_pos": 125, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn125", "evidence": [ { "id": "B6ZK76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZK76#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "B6ZK76-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Asn141", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 141, "start_aa": "Asn", "end_pos": 141, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn141", "evidence": [ { "id": "B6ZK76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZK76#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "B6ZK76-1", "start_pos": "216", "end_pos": "216", "site_lbl": "Asn216", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 216, "start_aa": "Asn", "end_pos": 216, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn216", "evidence": [ { "id": "B6ZK76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZK76#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "B6ZK76-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Asn267", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 267, "start_aa": "Asn", "end_pos": 267, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn267", "evidence": [ { "id": "B6ZK76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZK76#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "B6ZK76-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Asn334", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 334, "start_aa": "Asn", "end_pos": 334, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn334", "evidence": [ { "id": "B6ZK76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZK76#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "B6ZK76-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Asn64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 64, "start_aa": "Asn", "end_pos": 64, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn64", "evidence": [ { "id": "B6ZK76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZK76#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QJX5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QJX5", "url": "https://www.uniprot.org/uniprotkb/F1QJX5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1863, "chemical_mass": 210579.0, "gene_names": "ubr3;fb72f06;ubr3;wu:fb72f06", "protein_name": "E3 ubiquitin-protein ligase ubr3", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QJX5", "url": "https://www.uniprot.org/uniprotkb/F1QJX5" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "F1QJX5", "url": "https://www.uniprot.org/uniprotkb/F1QJX5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1QJX5", "url": "https://www.uniprot.org/uniprotkb/F1QJX5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1QJX5", "url": "https://www.uniprot.org/uniprotkb/F1QJX5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1QJX5", "url": "https://www.uniprot.org/uniprotkb/F1QJX5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the N-end rule pathway", "id": "GO:0071596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071596", "evidence": [ { "database": "UniProtKB", "id": "F1QJX5", "url": "https://www.uniprot.org/uniprotkb/F1QJX5" } ], "pmid": "" }, { "name": "eye morphogenesis", "id": "GO:0048592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048592", "evidence": [ { "database": "UniProtKB", "id": "F1QJX5", "url": "https://www.uniprot.org/uniprotkb/F1QJX5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WW08-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 637, "chemical_mass": 71730.0, "gene_names": "chfr;chfr;fc43f10;si:dkey-69h6.7;wu:fc43f10", "protein_name": "E3 ubiquitin-protein ligase CHFR", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" }, { "name": "mitotic G2/M transition checkpoint", "id": "GO:0044818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044818", "evidence": [ { "database": "UniProtKB", "id": "A5WW08", "url": "https://www.uniprot.org/uniprotkb/A5WW08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QDA1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1547, "chemical_mass": 164913.0, "gene_names": "acana;acana", "protein_name": "Aggrecan core protein", "disease": [ { "disease_id": "DOID:0112282", "name": "spondyloepiphyseal dysplasia Kimberley type", "description": "A spondyloepiphyseal dysplasia that has_material_basis_in heterozygous mutation in the ACAN gene on chromosome 15q26.1.", "url": "https://disease-ontology.org/term/DOID:0112282", "evidence": [ { "id": "0112282", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112282" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:4480", "name": "achondroplasia", "description": "An osteochondrodysplasia that is characterized by short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and midface hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, genu varum, and trident hand and that has_material_basis_in heterozygous mutation in the fibroblast growth factor receptor-3 gene (FGFR3) on chromosome 4p16.3. Achondroplasia results in dwarfism due to the abnormal ossification of cartilage in the long bone.", "url": "https://disease-ontology.org/term/DOID:4480", "evidence": [ { "id": "4480", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4480" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" }, { "name": "outflow tract morphogenesis", "id": "GO:0003151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003151", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" }, { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" }, { "name": "perineuronal net", "id": "GO:0072534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072534", "evidence": [ { "database": "UniProtKB", "id": "F1QDA1", "url": "https://www.uniprot.org/uniprotkb/F1QDA1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QDA1-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Thr114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 114, "start_aa": "Thr", "end_pos": 114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr114", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QDA1-1", "start_pos": "702", "end_pos": "702", "site_lbl": "Thr702", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 702, "start_aa": "Thr", "end_pos": 702, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr702", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q05159-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 412, "chemical_mass": 45153.0, "gene_names": "egr2b;KRX-20;cb427;egr2;id:ibd5073;krox20;krx-20;krx20;wu:fb71h10;zgc:92210", "protein_name": "Early growth response protein 2b", "disease": [ { "disease_id": "DOID:0050540", "name": "Charcot-Marie-Tooth disease type 3", "description": "A Charcot-Marie-Tooth disease that is characterized by motor and sensory peripheral neuropathies caused by demyelination.", "url": "https://disease-ontology.org/term/DOID:0050540", "evidence": [ { "id": "0050540", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050540" } ], "weight": 0.0 }, { "disease_id": "DOID:0110150", "name": "Charcot-Marie-Tooth disease type 1D", "description": "A Charcot-Marie-Tooth disease type 1 that has_material_basis_in mutation in the early growth response gene-2 (EGR2).", "url": "https://disease-ontology.org/term/DOID:0110150", "evidence": [ { "id": "0110150", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110150" } ], "weight": 0.0 }, { "disease_id": "DOID:0110195", "name": "congenital hypomyelinating neuropathy 1", "description": "A congenital hypomyelinating neuropathy that has_material_basis_in homozygous or heterozygous mutation in the EGR2 gene on chromosome 10q21.", "url": "https://disease-ontology.org/term/DOID:0110195", "evidence": [ { "id": "0110195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110195" } ], "weight": 0.0 }, { "disease_id": "DOID:2477", "name": "motor peripheral neuropathy", "description": "A neuropathy that is characterized by inflammation or degeneration of the peripheral motor nerves.", "url": "https://disease-ontology.org/term/DOID:2477", "evidence": [ { "id": "2477", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2477" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" }, { "name": "hindbrain morphogenesis", "id": "GO:0021575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021575", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" }, { "name": "myelination of posterior lateral line nerve axons", "id": "GO:0048932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048932", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" }, { "name": "rhombomere boundary formation", "id": "GO:0021654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021654", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q05159", "url": "https://www.uniprot.org/uniprotkb/Q05159" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A6H8I0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A6H8I0", "url": "https://www.uniprot.org/uniprotkb/A6H8I0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 506, "chemical_mass": 58120.0, "gene_names": "usp22;usp22;zgc:136342", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 22", "disease": [ { "disease_id": "DOID:0112036", "name": "non-syndromic X-linked intellectual disability 105", "description": "A non-syndromic X-linked intellectual disability characterized by borderline to moderate intellectual disability, variable poor or absent speech, and behavioral problems that has_material_basis_in hemizygous mutation in the USP27X gene on chromosome Xp11.23.", "url": "https://disease-ontology.org/term/DOID:0112036", "evidence": [ { "id": "0112036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112036" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A6H8I0", "url": "https://www.uniprot.org/uniprotkb/A6H8I0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A6H8I0", "url": "https://www.uniprot.org/uniprotkb/A6H8I0" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A6H8I0", "url": "https://www.uniprot.org/uniprotkb/A6H8I0" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A6H8I0", "url": "https://www.uniprot.org/uniprotkb/A6H8I0" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A6H8I0", "url": "https://www.uniprot.org/uniprotkb/A6H8I0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A6H8I0", "url": "https://www.uniprot.org/uniprotkb/A6H8I0" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A6H8I0", "url": "https://www.uniprot.org/uniprotkb/A6H8I0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08BM8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 286, "chemical_mass": 32876.0, "gene_names": "cnot7;CAF1;caf1;cnot7;fd59c07;fj07d05;wu:fd59c07;wu:fj07d05;zgc:153168", "protein_name": "CCR4-NOT transcription complex subunit 7", "disease": [ { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 }, { "disease_id": "DOID:12336", "name": "male infertility", "description": "", "url": "https://disease-ontology.org/term/DOID:12336", "evidence": [ { "id": "12336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12336" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "RNA exonuclease activity", "id": "GO:0004532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004532", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "CCR4-NOT core complex", "id": "GO:0030015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030015", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "miRNA-mediated gene silencing by mRNA destabilization", "id": "GO:0035279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035279", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060213", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900153", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:0000288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000288", "evidence": [ { "database": "UniProtKB", "id": "Q08BM8", "url": "https://www.uniprot.org/uniprotkb/Q08BM8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WG57-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 335, "chemical_mass": 35891.0, "gene_names": "hmgcll1;hmgcll1;zgc:172206", "protein_name": "3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic", "disease": [ { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" }, { "name": "hydroxymethylglutaryl-CoA lyase activity", "id": "GO:0004419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004419", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" } ], "biological_process": [ { "name": "ketone body biosynthetic process", "id": "GO:0046951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046951", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" }, { "name": "L-leucine catabolic process", "id": "GO:0006552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006552", "evidence": [ { "database": "UniProtKB", "id": "A8WG57", "url": "https://www.uniprot.org/uniprotkb/A8WG57" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BG85-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 517, "chemical_mass": 59368.0, "gene_names": "chrne;chrne;im:7154697;zgc:101010", "protein_name": "", "disease": [ { "disease_id": "DOID:0110677", "name": "congenital myasthenic syndrome 4B", "description": "A congenital myasthenic syndrome characterized by autosomal recessive inheritance of postsynaptic neuromuscular junction defects, early-onset progressive muscle weakness, and kinetic abnormalities of the AChR channel that has_material_basis_in homozygous or compound heterozygous mutation in the CHRNE gene on chromosome 17p13.", "url": "https://disease-ontology.org/term/DOID:0110677", "evidence": [ { "id": "0110677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110677" } ], "weight": 0.0 }, { "disease_id": "DOID:0110678", "name": "congenital myasthenic syndrome 4A", "description": "A congenital myasthenic syndrome characterized by postsynaptic neuromuscular junction defects, early-onset progressive muscle weakness, and prolonged opening and activity of the acetylcholine receptor channel that has_material_basis_in heterozygous or rarely biallelic mutation in the CHRNE gene on chromosome 17p13.", "url": "https://disease-ontology.org/term/DOID:0110678", "evidence": [ { "id": "0110678", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110678" } ], "weight": 0.0 }, { "disease_id": "DOID:0110679", "name": "congenital myasthenic syndrome 4C", "description": "A congenital myasthenic syndrome characterized by autosomal recessive inheritance of postsynaptic neuromuscular junction defects, early-onset muscle weakness, and low amplitude of the miniature endplate potential and current that has_material_basis_in homozygous or compound heterozygous mutation in the CHRNE gene on chromosome 17p13.", "url": "https://disease-ontology.org/term/DOID:0110679", "evidence": [ { "id": "0110679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110679" } ], "weight": 0.0 } ], "biological_process": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "synaptic transmission, cholinergic", "id": "GO:0007271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007271", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "acetylcholine receptor signaling pathway", "id": "GO:0095500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0095500", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "membrane depolarization", "id": "GO:0051899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051899", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "cellular response to acetylcholine", "id": "GO:1905145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905145", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "acetylcholine-gated monoatomic cation-selective channel activity", "id": "GO:0022848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022848", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "acetylcholine-gated channel complex", "id": "GO:0005892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005892", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A2BG85", "url": "https://www.uniprot.org/uniprotkb/A2BG85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BGG1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGG1", "url": "https://www.uniprot.org/uniprotkb/A2BGG1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 736, "chemical_mass": 84796.0, "gene_names": "mtmr12;im:7160376;pip3ap;si:dkey-207e22.3", "protein_name": "Myotubularin-related protein 12", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BGG1", "url": "https://www.uniprot.org/uniprotkb/A2BGG1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A2BGG1", "url": "https://www.uniprot.org/uniprotkb/A2BGG1" } ], "pmid": "" }, { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "A2BGG1", "url": "https://www.uniprot.org/uniprotkb/A2BGG1" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "A2BGG1", "url": "https://www.uniprot.org/uniprotkb/A2BGG1" } ], "pmid": "" } ], "biological_process": [ { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A2BGG1", "url": "https://www.uniprot.org/uniprotkb/A2BGG1" } ], "pmid": "" }, { "name": "skeletal muscle fiber development", "id": "GO:0048741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048741", "evidence": [ { "database": "UniProtKB", "id": "A2BGG1", "url": "https://www.uniprot.org/uniprotkb/A2BGG1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BGR3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1451, "chemical_mass": 163227.0, "gene_names": "ercc6l;si:ch211-278b8.3", "protein_name": "DNA excision repair protein ERCC-6-like", "disease": [ { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" }, { "name": "DNA translocase activity", "id": "GO:0015616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015616", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" }, { "name": "intein-mediated protein splicing", "id": "GO:0016539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016539", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" } ], "cellular_component": [ { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2BGR3-1", "start_pos": "961", "end_pos": "961", "site_lbl": "Ser961", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A2BGR3", "url": "https://www.uniprot.org/uniprotkb/A2BGR3" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A2BGR3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BGR3" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BIC6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIC6", "url": "https://www.uniprot.org/uniprotkb/A2BIC6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 517, "chemical_mass": 55368.0, "gene_names": "lap3;im:7150907;lap3", "protein_name": "Cytosol aminopeptidase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BIC6", "url": "https://www.uniprot.org/uniprotkb/A2BIC6" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A2BIC6", "url": "https://www.uniprot.org/uniprotkb/A2BIC6" } ], "pmid": "" } ], "molecular_function": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A2BIC6", "url": "https://www.uniprot.org/uniprotkb/A2BIC6" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "A2BIC6", "url": "https://www.uniprot.org/uniprotkb/A2BIC6" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A2BIC6", "url": "https://www.uniprot.org/uniprotkb/A2BIC6" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "A2BIC6", "url": "https://www.uniprot.org/uniprotkb/A2BIC6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2BIC6-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Thr209", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 209, "start_aa": "Thr", "end_pos": 209, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr209", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CEX1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEX1", "url": "https://www.uniprot.org/uniprotkb/A2CEX1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 751, "chemical_mass": 82852.0, "gene_names": "zdhhc8b;dhhc8;zdhhc5;zisp", "protein_name": "Palmitoyltransferase ZDHHC8B", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A2CEX1", "url": "https://www.uniprot.org/uniprotkb/A2CEX1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A2CEX1", "url": "https://www.uniprot.org/uniprotkb/A2CEX1" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A2CEX1", "url": "https://www.uniprot.org/uniprotkb/A2CEX1" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cholesterol efflux", "id": "GO:0010875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010875", "evidence": [ { "database": "UniProtKB", "id": "A2CEX1", "url": "https://www.uniprot.org/uniprotkb/A2CEX1" } ], "pmid": "" }, { "name": "peptidyl-L-cysteine S-palmitoylation", "id": "GO:0018230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018230", "evidence": [ { "database": "UniProtKB", "id": "A2CEX1", "url": "https://www.uniprot.org/uniprotkb/A2CEX1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A2CEX1", "url": "https://www.uniprot.org/uniprotkb/A2CEX1" } ], "pmid": "" }, { "name": "palmitoyltransferase activity", "id": "GO:0016409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016409", "evidence": [ { "database": "UniProtKB", "id": "A2CEX1", "url": "https://www.uniprot.org/uniprotkb/A2CEX1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2CEX1-1", "start_pos": "265", "end_pos": "265", "site_lbl": "Thr265", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 265, "start_aa": "Thr", "end_pos": 265, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr265", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A2CEX1-1", "start_pos": "345", "end_pos": "345", "site_lbl": "Thr345", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A2CEX1-1", "start_pos": "612", "end_pos": "612", "site_lbl": "Thr612", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 612, "start_aa": "Thr", "end_pos": 612, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr612", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A2CEX1-1", "start_pos": "725", "end_pos": "725", "site_lbl": "Thr725", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 725, "start_aa": "Thr", "end_pos": 725, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr725", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A2CEX1-1", "start_pos": "729", "end_pos": "729", "site_lbl": "Thr729", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 729, "start_aa": "Thr", "end_pos": 729, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr729", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2VD23-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2VD23", "url": "https://www.uniprot.org/uniprotkb/A2VD23" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 613, "chemical_mass": 66175.0, "gene_names": "stm;cb885;id:ibd5112;sb:cb148;sb:cb568;sb:cb584;si:ch211-80h18.3;stm", "protein_name": "Protein starmaker", "disease": [], "biological_process": [ { "name": "detection of gravity", "id": "GO:0009590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009590", "evidence": [ { "database": "UniProtKB", "id": "A2VD23", "url": "https://www.uniprot.org/uniprotkb/A2VD23" } ], "pmid": "" }, { "name": "otolith morphogenesis", "id": "GO:0032474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032474", "evidence": [ { "database": "UniProtKB", "id": "A2VD23", "url": "https://www.uniprot.org/uniprotkb/A2VD23" } ], "pmid": "" }, { "name": "egg coat formation", "id": "GO:0035803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035803", "evidence": [ { "database": "UniProtKB", "id": "A2VD23", "url": "https://www.uniprot.org/uniprotkb/A2VD23" } ], "pmid": "" }, { "name": "otolith mineralization", "id": "GO:0045299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045299", "evidence": [ { "database": "UniProtKB", "id": "A2VD23", "url": "https://www.uniprot.org/uniprotkb/A2VD23" } ], "pmid": "" }, { "name": "otic placode formation", "id": "GO:0043049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043049", "evidence": [ { "database": "UniProtKB", "id": "A2VD23", "url": "https://www.uniprot.org/uniprotkb/A2VD23" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A2VD23", "url": "https://www.uniprot.org/uniprotkb/A2VD23" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A2VD23", "url": "https://www.uniprot.org/uniprotkb/A2VD23" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2VD23-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Thr544", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 544, "start_aa": "Thr", "end_pos": 544, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr544", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KNJ3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 353, "chemical_mass": 38759.0, "gene_names": "foxi3a;foxi3a;foxi3", "protein_name": "Forkhead box protein I3-A", "disease": [ { "disease_id": "DOID:0060744", "name": "Pendred Syndrome", "description": "A syndrome characterized by bilateral prelingual sensorineural hearing loss and euthyroid goiter and that has_material_basis_in homozygous or compound heterozygous mutation in the SLC26A4 gene on chromosome 7q.", "url": "https://disease-ontology.org/term/DOID:0060744", "evidence": [ { "id": "0060744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060744" } ], "weight": 0.0 }, { "disease_id": "DOID:0110498", "name": "autosomal recessive nonsyndromic deafness 4", "description": "An autosomal recessive nonsyndromic deafness that has_material_basis_in mutation in the SLC26A4 gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0110498", "evidence": [ { "id": "0110498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110498" } ], "weight": 0.0 }, { "disease_id": "DOID:2907", "name": "Goldenhar syndrome", "description": "A syndrome that is characterized by incomplete development of the ear, nose, soft palate, lip, and mandible. It is associated with anomalous development of the first branchial arch and second branchial arch.", "url": "https://disease-ontology.org/term/DOID:2907", "evidence": [ { "id": "2907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2907" } ], "weight": 0.0 } ], "biological_process": [ { "name": "epidermal cell differentiation", "id": "GO:0009913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009913", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" }, { "name": "multicellular organismal-level water homeostasis", "id": "GO:0050891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050891", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" }, { "name": "epidermal cell fate specification", "id": "GO:0009957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009957", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" }, { "name": "ionocyte differentiation", "id": "GO:0062236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062236", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ3", "url": "https://www.uniprot.org/uniprotkb/A3KNJ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KNS9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 230, "chemical_mass": 25580.0, "gene_names": "atraid;APR-3;apr3;atraid;si:ch211-101l18.3", "protein_name": "All-trans retinoic acid-induced differentiation factor", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" } ], "biological_process": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" }, { "name": "positive regulation of bone mineralization", "id": "GO:0030501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030501", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" }, { "name": "positive regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" }, { "name": "negative regulation of protein catabolic process", "id": "GO:0042177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042177", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" }, { "name": "negative regulation of osteoblast proliferation", "id": "GO:0033689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033689", "evidence": [ { "database": "UniProtKB", "id": "A3KNS9", "url": "https://www.uniprot.org/uniprotkb/A3KNS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KNW0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 227, "chemical_mass": 25866.0, "gene_names": "pld6;fc55d08;pld6;wu:fc55d08;zgc:162591", "protein_name": "Mitochondrial cardiolipin hydrolase", "disease": [], "biological_process": [ { "name": "P granule organization", "id": "GO:0030719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030719", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "cardiolipin hydrolase activity", "id": "GO:0035755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035755", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism", "id": "GO:0016891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016891", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A3KNW0", "url": "https://www.uniprot.org/uniprotkb/A3KNW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KP59-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 544, "chemical_mass": 61517.0, "gene_names": "riox1;im:7141580;no66a;no66;riox1;zgc:162967", "protein_name": "Ribosomal oxygenase 1", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "histone H3K36 demethylase activity", "id": "GO:0051864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051864", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "histone H3K4me/H3K4me2/H3K4me3 demethylase activity", "id": "GO:0034647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034647", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "histone H3K4 demethylase activity", "id": "GO:0032453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032453", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "peptidyl-histidine dioxygenase activity", "id": "GO:0036139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036139", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "histone H3K36me/H3K36me2 demethylase activity", "id": "GO:0140680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140680", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "protein demethylase activity", "id": "GO:0140457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140457", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" }, { "name": "negative regulation of osteoblast differentiation", "id": "GO:0045668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", "evidence": [ { "database": "UniProtKB", "id": "A3KP59", "url": "https://www.uniprot.org/uniprotkb/A3KP59" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KPK0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 860, "chemical_mass": 97332.0, "gene_names": "ago3b;ago3;Argonaute3;ago3b;ago3;eif2c3b;eif2c3;sb:eu332;si:dkey-3n22.3", "protein_name": "Protein argonaute-3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "miRNA binding", "id": "GO:0035198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035198", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "endoribonuclease activity, cleaving miRNA-paired mRNA", "id": "GO:0090624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090624", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031054", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated post-transcriptional gene silencing", "id": "GO:0035194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035194", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "miRNA-mediated gene silencing by inhibition of translation", "id": "GO:0035278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035278", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" }, { "name": "regulation of stem cell proliferation", "id": "GO:0072091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072091", "evidence": [ { "database": "UniProtKB", "id": "A3KPK0", "url": "https://www.uniprot.org/uniprotkb/A3KPK0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KPR5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KPR5", "url": "https://www.uniprot.org/uniprotkb/A3KPR5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 247, "chemical_mass": 27426.0, "gene_names": "cyb561a3a;cyb561a3a;cyb561a3;cybasc3a;cybasc3;si:dkeyp-38h2.4", "protein_name": "Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A3KPR5", "url": "https://www.uniprot.org/uniprotkb/A3KPR5" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A3KPR5", "url": "https://www.uniprot.org/uniprotkb/A3KPR5" } ], "pmid": "" }, { "name": "transmembrane ascorbate ferrireductase activity", "id": "GO:0140571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140571", "evidence": [ { "database": "UniProtKB", "id": "A3KPR5", "url": "https://www.uniprot.org/uniprotkb/A3KPR5" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A3KPR5", "url": "https://www.uniprot.org/uniprotkb/A3KPR5" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A3KPR5", "url": "https://www.uniprot.org/uniprotkb/A3KPR5" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A3KPR5", "url": "https://www.uniprot.org/uniprotkb/A3KPR5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A3KPR5-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Asn189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 189, "start_aa": "Asn", "end_pos": 189, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn189", "evidence": [ { "id": "A3KPR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPR5#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KQX1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQX1", "url": "https://www.uniprot.org/uniprotkb/A3KQX1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 474, "chemical_mass": 53230.0, "gene_names": "cndp2;CN2;cndp2;wu:fd20d11;wu:fe17f09;zgc:92569", "protein_name": "Cytosolic non-specific dipeptidase", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A3KQX1", "url": "https://www.uniprot.org/uniprotkb/A3KQX1" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A3KQX1", "url": "https://www.uniprot.org/uniprotkb/A3KQX1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A3KQX1", "url": "https://www.uniprot.org/uniprotkb/A3KQX1" } ], "pmid": "" }, { "name": "carboxypeptidase activity", "id": "GO:0004180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004180", "evidence": [ { "database": "UniProtKB", "id": "A3KQX1", "url": "https://www.uniprot.org/uniprotkb/A3KQX1" } ], "pmid": "" }, { "name": "metallodipeptidase activity", "id": "GO:0070573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070573", "evidence": [ { "database": "UniProtKB", "id": "A3KQX1", "url": "https://www.uniprot.org/uniprotkb/A3KQX1" } ], "pmid": "" }, { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "A3KQX1", "url": "https://www.uniprot.org/uniprotkb/A3KQX1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3RK74-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 652, "chemical_mass": 69348.0, "gene_names": "foxo1a;FoxO1a.1;foxO1a.1;foxo1a;foxo1;zgc:153388", "protein_name": "Forkhead box protein O1-A", "disease": [ { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:4051", "name": "alveolar rhabdomyosarcoma", "description": "", "url": "https://disease-ontology.org/term/DOID:4051", "evidence": [ { "id": "4051", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4051" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" }, { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" }, { "name": "smooth muscle cell differentiation", "id": "GO:0051145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051145", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" }, { "name": "smooth muscle cell proliferation", "id": "GO:0048659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048659", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" }, { "name": "lymph vessel development", "id": "GO:0001945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001945", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" }, { "name": "smooth muscle tissue development", "id": "GO:0048745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048745", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A3RK74", "url": "https://www.uniprot.org/uniprotkb/A3RK74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4FUN7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 371, "chemical_mass": 43027.0, "gene_names": "usp12a;sb:eu882;usp12a;usp12;wu:fi09d12", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12A", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A4FUN7", "url": "https://www.uniprot.org/uniprotkb/A4FUN7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IG32-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 489, "chemical_mass": 55925.0, "gene_names": "micu1;cbara1;micu1;si:ch211-199i24.4;zgc:162148", "protein_name": "Calcium uptake protein 1, mitochondrial", "disease": [ { "disease_id": "DOID:0111335", "name": "myopathy with extrapyramidal signs", "description": "A myopathy characterized by early childhood onset of proximal muscle weakness, with development of progressive extrapyramidal motor signs in most patients, and learning disabilities that has_material_basis_in compound heterozygous or homozygous mutation in the MICU1 gene on chromosome 10q22.1.", "url": "https://disease-ontology.org/term/DOID:0111335", "evidence": [ { "id": "0111335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111335" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "uniplex complex", "id": "GO:1990246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990246", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "calcium channel complex", "id": "GO:0034704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034704", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial calcium ion transmembrane transport", "id": "GO:0006851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006851", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "calcium import into the mitochondrion", "id": "GO:0036444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036444", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "positive regulation of cristae formation", "id": "GO:1903852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903852", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial calcium ion concentration", "id": "GO:0051561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051561", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" }, { "name": "calcium ion import", "id": "GO:0070509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070509", "evidence": [ { "database": "UniProtKB", "id": "A4IG32", "url": "https://www.uniprot.org/uniprotkb/A4IG32" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IG59-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 481, "chemical_mass": 52112.0, "gene_names": "washc1;Wash1;si:ch211-11f8.1;wash1;washc1;wash", "protein_name": "WASH complex subunit 1", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" } ], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "WASH complex", "id": "GO:0071203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071203", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A4IG59", "url": "https://www.uniprot.org/uniprotkb/A4IG59" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4ZNR4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 409, "chemical_mass": 47062.0, "gene_names": "nkd2;nkd2a;nkd2", "protein_name": "Protein naked cuticle homolog 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "pmid": "" }, { "name": "Kupffer's vesicle development", "id": "GO:0070121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070121", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "pmid": "" }, { "name": "Spemann organizer formation", "id": "GO:0060061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060061", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR4", "url": "https://www.uniprot.org/uniprotkb/A4ZNR4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PLE7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 368, "chemical_mass": 41705.0, "gene_names": "gpr183a;ebi2;gpr183a;gpr183;zgc:165579", "protein_name": "G protein-coupled receptor 183-A", "disease": [], "biological_process": [ { "name": "osteoclast differentiation", "id": "GO:0030316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030316", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "dendritic cell homeostasis", "id": "GO:0036145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036145", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "regulation of astrocyte chemotaxis", "id": "GO:2000458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000458", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "dendritic cell chemotaxis", "id": "GO:0002407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002407", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "T cell chemotaxis", "id": "GO:0010818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010818", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "leukocyte chemotaxis", "id": "GO:0030595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030595", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "T follicular helper cell differentiation", "id": "GO:0061470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061470", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "endothelial to hematopoietic transition", "id": "GO:0098508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098508", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxysterol binding", "id": "GO:0008142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008142", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" }, { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A5PLE7", "url": "https://www.uniprot.org/uniprotkb/A5PLE7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5PLE7-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Asn11", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 11, "start_aa": "Asn", "end_pos": 11, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn11", "evidence": [ { "id": "A5PLE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PLE7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5PLE7-1", "start_pos": "7", "end_pos": "7", "site_lbl": "Asn7", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 7, "start_aa": "Asn", "end_pos": 7, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn7", "evidence": [ { "id": "A5PLE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PLE7#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMR2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 897, "chemical_mass": 100655.0, "gene_names": "usp33;ch211-284g18.1;usp33;zgc:77308", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "centrosome duplication", "id": "GO:0051298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051298", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A5PMR2", "url": "https://www.uniprot.org/uniprotkb/A5PMR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMX1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 387, "chemical_mass": 42568.0, "gene_names": "slc30a7;ZnT-7;ZnT7;si:ch211-190n7.2;si:dkey-6p9.3;slc30a7;wu:fi11a08;zgc:55366;znt7", "protein_name": "Zinc transporter 7", "disease": [ { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" } ], "biological_process": [ { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" }, { "name": "zinc ion import into Golgi lumen", "id": "GO:1904257", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904257", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi cis cisterna membrane", "id": "GO:1990674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990674", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "A5PMX1", "url": "https://www.uniprot.org/uniprotkb/A5PMX1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMY6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 720, "chemical_mass": 78035.0, "gene_names": "colec12;cb377;colec12;hm:zeh0853;id:ibd2826;sb:cb377;si:ch211-212m21.5;zeh0853", "protein_name": "Collectin-12", "disease": [], "biological_process": [ { "name": "vasculogenesis", "id": "GO:0001570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001570", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" }, { "name": "phagocytosis, recognition", "id": "GO:0006910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006910", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" }, { "name": "low-density lipoprotein particle binding", "id": "GO:0030169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030169", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "A5PMY6", "url": "https://www.uniprot.org/uniprotkb/A5PMY6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5PMY6-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Thr536", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 536, "start_aa": "Thr", "end_pos": 536, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr536", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A5PMY6-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Thr601", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 601, "start_aa": "Thr", "end_pos": 601, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr601", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PN43-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 520, "chemical_mass": 59013.0, "gene_names": "tmem175;si:ch211-168m18.2", "protein_name": "Endosomal/lysosomal proton channel TMEM175", "disease": [], "molecular_function": [ { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "arachidonate binding", "id": "GO:0050544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050544", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "proton channel activity", "id": "GO:0015252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015252", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "lysosomal lumen pH elevation", "id": "GO:0035752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035752", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "phagosome-lysosome fusion", "id": "GO:0090385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090385", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" }, { "name": "regulation of lysosomal lumen pH", "id": "GO:0035751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035751", "evidence": [ { "database": "UniProtKB", "id": "A5PN43", "url": "https://www.uniprot.org/uniprotkb/A5PN43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5PN43-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Thr336", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 336, "start_aa": "Thr", "end_pos": 336, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr336", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WVX0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 203, "chemical_mass": 22869.0, "gene_names": "itpa;itpa;si:ch73-18j6.1;si:dkey-19f21.1", "protein_name": "Inosine triphosphate pyrophosphatase", "disease": [ { "disease_id": "DOID:0080458", "name": "developmental and epileptic encephalopathy 35", "description": "A developmental and epileptic encephalopathy characterized by seizure onset in the first months of life, absence of normal development and absence of myelination of early neurological structures that has_material_basis_in homozygous or compound heterozygous mutation in the ITPA gene on chromosome 20p13.", "url": "https://disease-ontology.org/term/DOID:0080458", "evidence": [ { "id": "0080458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080458" } ], "weight": 0.0 }, { "disease_id": "DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood.", "url": "https://disease-ontology.org/term/DOID:1588", "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ], "weight": 0.0 }, { "disease_id": "DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:1883", "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:583", "name": "hemolytic anemia", "description": "A normocytic anemia that is characterized by the rate of descruction of red blood cells exceeding the rate than they can be made.", "url": "https://disease-ontology.org/term/DOID:583", "evidence": [ { "id": "583", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:583" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" }, { "name": "nucleoside triphosphate catabolic process", "id": "GO:0009143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009143", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" }, { "name": "deoxyribonucleoside triphosphate catabolic process", "id": "GO:0009204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009204", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" }, { "name": "nucleoside triphosphate diphosphatase activity", "id": "GO:0047429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047429", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" }, { "name": "dITP diphosphatase activity", "id": "GO:0035870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035870", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" }, { "name": "ITP diphosphatase activity", "id": "GO:0036220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036220", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" }, { "name": "XTP diphosphatase activity", "id": "GO:0036222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036222", "evidence": [ { "database": "UniProtKB", "id": "A5WVX0", "url": "https://www.uniprot.org/uniprotkb/A5WVX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WVX8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WVX8", "url": "https://www.uniprot.org/uniprotkb/A5WVX8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 468, "chemical_mass": 52382.0, "gene_names": "metap2a;METAP2;metap2a;metap2l", "protein_name": "Methionine aminopeptidase 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5WVX8", "url": "https://www.uniprot.org/uniprotkb/A5WVX8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A5WVX8", "url": "https://www.uniprot.org/uniprotkb/A5WVX8" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A5WVX8", "url": "https://www.uniprot.org/uniprotkb/A5WVX8" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "A5WVX8", "url": "https://www.uniprot.org/uniprotkb/A5WVX8" } ], "pmid": "" }, { "name": "metalloexopeptidase activity", "id": "GO:0008235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008235", "evidence": [ { "database": "UniProtKB", "id": "A5WVX8", "url": "https://www.uniprot.org/uniprotkb/A5WVX8" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "A5WVX8", "url": "https://www.uniprot.org/uniprotkb/A5WVX8" } ], "pmid": "" }, { "name": "initiator methionyl aminopeptidase activity", "id": "GO:0004239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004239", "evidence": [ { "database": "UniProtKB", "id": "A5WVX8", "url": "https://www.uniprot.org/uniprotkb/A5WVX8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WWA0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 868, "chemical_mass": 94667.0, "gene_names": "znrf3;si:ct737139.3;si:dkeyp-7c9.3", "protein_name": "E3 ubiquitin-protein ligase znrf3", "disease": [], "molecular_function": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "stem cell proliferation", "id": "GO:0072089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072089", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "Wnt receptor catabolic process", "id": "GO:0038018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038018", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" }, { "name": "negative regulation of non-canonical Wnt signaling pathway", "id": "GO:2000051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000051", "evidence": [ { "database": "UniProtKB", "id": "A5WWA0", "url": "https://www.uniprot.org/uniprotkb/A5WWA0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A6NAF9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1079, "chemical_mass": 121331.0, "gene_names": "tdrd7a;si:ch211-288h2.2;tdrd7;wu:fi12c12;zgc:56669", "protein_name": "Tudor domain-containing protein 7A", "disease": [ { "disease_id": "DOID:0110247", "name": "cataract 36", "description": "A cataract that has_material_basis_in homozygous mutation in the TDRD7 gene on chromosome 9q22.33.", "url": "https://disease-ontology.org/term/DOID:0110247", "evidence": [ { "id": "0110247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110247" } ], "weight": 0.0 } ], "biological_process": [ { "name": "P granule organization", "id": "GO:0030719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030719", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" }, { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" }, { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" }, { "name": "lens morphogenesis in camera-type eye", "id": "GO:0002089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002089", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" }, { "name": "lens fiber cell differentiation", "id": "GO:0070306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070306", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" } ], "cellular_component": [ { "name": "ribonucleoprotein granule", "id": "GO:0035770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035770", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "A6NAF9", "url": "https://www.uniprot.org/uniprotkb/A6NAF9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A6NAF9-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Thr355", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 355, "start_aa": "Thr", "end_pos": 355, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr355", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A7MBP4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 384, "chemical_mass": 43342.0, "gene_names": "ift46", "protein_name": "Intraflagellar transport protein 46 homolog", "disease": [], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" } ], "biological_process": [ { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" }, { "name": "determination of ventral identity", "id": "GO:0048264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048264", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" }, { "name": "pronephros development", "id": "GO:0048793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048793", "evidence": [ { "database": "UniProtKB", "id": "A7MBP4", "url": "https://www.uniprot.org/uniprotkb/A7MBP4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8KBY2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 423, "chemical_mass": 48439.0, "gene_names": "brf2;brf2;si:ch211-271b8.2;wu:fj22c04;zgc:100856", "protein_name": "Transcription factor IIIB 50 kDa subunit", "disease": [], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "startle response", "id": "GO:0001964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001964", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase III", "id": "GO:0006359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006359", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "transcription preinitiation complex assembly", "id": "GO:0070897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070897", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "swimming", "id": "GO:0036268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036268", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" } ], "cellular_component": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "transcription factor TFIIIB complex", "id": "GO:0000126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000126", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" }, { "name": "RNA polymerase III type 3 promoter sequence-specific DNA binding", "id": "GO:0001006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001006", "evidence": [ { "database": "UniProtKB", "id": "A8KBY2", "url": "https://www.uniprot.org/uniprotkb/A8KBY2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WE67-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 631, "chemical_mass": 72816.0, "gene_names": "kifbp;fc59b03;kbp;kiaa1279;kif1bp;unst23;wu:fc59b03;zgc:112085", "protein_name": "KIF-binding protein", "disease": [ { "disease_id": "DOID:0060481", "name": "Goldberg-Shprintzen syndrome", "description": "A syndrome characterized by intellectual disability, specific facial gestalt and Hirschsprung's disease and that has_material_basis_in homozygous mutation in the KIAA1279 gene on chromosome 10q21.1.", "url": "https://disease-ontology.org/term/DOID:0060481", "evidence": [ { "id": "0060481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060481" } ], "weight": 0.0 } ], "biological_process": [ { "name": "enteric nervous system development", "id": "GO:0048484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048484", "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "pmid": "" }, { "name": "mitochondrion transport along microtubule", "id": "GO:0047497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047497", "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "pmid": "" }, { "name": "neuron projection maintenance", "id": "GO:1990535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990535", "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "pmid": "" }, { "name": "central nervous system projection neuron axonogenesis", "id": "GO:0021952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952", "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "pmid": "" }, { "name": "efferent axon development in posterior lateral line nerve", "id": "GO:0048929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048929", "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A8WE67", "url": "https://www.uniprot.org/uniprotkb/A8WE67" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WFR0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 275, "chemical_mass": 30686.0, "gene_names": "lamp5;zgc:165600;LAMP-5;lamp5;zgc:165600", "protein_name": "Lysosome-associated membrane glycoprotein 5", "disease": [], "cellular_component": [ { "name": "growth cone membrane", "id": "GO:0032584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032584", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" } ], "biological_process": [ { "name": "establishment of protein localization to organelle", "id": "GO:0072594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072594", "evidence": [ { "database": "UniProtKB", "id": "A8WFR0", "url": "https://www.uniprot.org/uniprotkb/A8WFR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8WFR0-1", "start_pos": "24", "end_pos": "24", "site_lbl": "Asn24", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 24, "start_aa": "Asn", "end_pos": 24, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn24", "evidence": [ { "id": "A8WFR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WFR0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A8WFR0-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Asn42", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 42, "start_aa": "Asn", "end_pos": 42, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn42", "evidence": [ { "id": "A8WFR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WFR0#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WHR3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WHR3", "url": "https://www.uniprot.org/uniprotkb/A8WHR3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 345, "chemical_mass": 38858.0, "gene_names": "yju2;ccdc94;sb:eu776;yju2;zgc:55914", "protein_name": "Splicing factor YJU2", "disease": [], "biological_process": [ { "name": "generation of catalytic spliceosome for first transesterification step", "id": "GO:0000349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000349", "evidence": [ { "database": "UniProtKB", "id": "A8WHR3", "url": "https://www.uniprot.org/uniprotkb/A8WHR3" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A8WHR3", "url": "https://www.uniprot.org/uniprotkb/A8WHR3" } ], "pmid": "" }, { "name": "negative regulation of DNA damage response, signal transduction by p53 class mediator", "id": "GO:0043518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043518", "evidence": [ { "database": "UniProtKB", "id": "A8WHR3", "url": "https://www.uniprot.org/uniprotkb/A8WHR3" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "A8WHR3", "url": "https://www.uniprot.org/uniprotkb/A8WHR3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A8WHR3", "url": "https://www.uniprot.org/uniprotkb/A8WHR3" } ], "pmid": "" } ], "cellular_component": [ { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "A8WHR3", "url": "https://www.uniprot.org/uniprotkb/A8WHR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WIN7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 730, "chemical_mass": 84282.0, "gene_names": "plod1a;fc95g08;fi18a05;ik:tdsubs_rzpd609-29b19;plod1a;plod1;plod;wu:fc29c10;wu:fc95g08;wu:fi18a05;zgc:152876", "protein_name": "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "disease": [ { "disease_id": "DOID:0080734", "name": "Ehlers-Danlos syndrome kyphoscoliotic type 1", "description": "An Ehlers-Danlos syndrome that is characterized by severe muscle hypotonia at birth, generalized joint laxity, scoliosis at birth, and scleral fragility and rupture of the ocular globe and that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding lysyl hydroxylase (PLOD1) on chromosome 1p36.", "url": "https://disease-ontology.org/term/DOID:0080734", "evidence": [ { "id": "0080734", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080734" } ], "weight": 0.0 }, { "disease_id": "DOID:13359", "name": "Ehlers-Danlos syndrome", "description": "A collagen disease that is characterized by extremely flexible joints, elastic skin, and excessive bruising caused by a heritable defect in collagen synthesis, which leads to marked healing difficulties. EDS has five cardinal signs, which may be present to some degree in all of the subtypes. These five cardinal signs are skin fragility, blood vessel fragility, skin hyperelasticity, joint hypermobility, and characteristic subcutaneous nodules.", "url": "https://disease-ontology.org/term/DOID:13359", "evidence": [ { "id": "13359", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13359" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" }, { "name": "procollagen-lysine 5-dioxygenase activity", "id": "GO:0008475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008475", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum membrane", "id": "GO:0030867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030867", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" } ], "biological_process": [ { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" }, { "name": "fin development", "id": "GO:0033333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033333", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" }, { "name": "fin morphogenesis", "id": "GO:0033334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033334", "evidence": [ { "database": "UniProtKB", "id": "A8WIN7", "url": "https://www.uniprot.org/uniprotkb/A8WIN7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9JR78-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JR78", "url": "https://www.uniprot.org/uniprotkb/A9JR78" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1427, "chemical_mass": 158305.0, "gene_names": "tonsl;im:7145273;nfkbil2;tonsl;zgc:171416", "protein_name": "Tonsoku-like protein", "disease": [ { "disease_id": "DOID:5684", "name": "spondyloepimetaphyseal dysplasia, Sponastrime type", "description": "A spondyloepimetaphyseal dysplasia that is characterized by spondylar and nasal changes, with striations of the metaphyses that has_material_basis_in autosomal recessive inheritance.", "url": "https://disease-ontology.org/term/DOID:5684", "evidence": [ { "id": "5684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "A9JR78", "url": "https://www.uniprot.org/uniprotkb/A9JR78" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A9JR78", "url": "https://www.uniprot.org/uniprotkb/A9JR78" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A9JR78", "url": "https://www.uniprot.org/uniprotkb/A9JR78" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A9JR78", "url": "https://www.uniprot.org/uniprotkb/A9JR78" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "A9JR78", "url": "https://www.uniprot.org/uniprotkb/A9JR78" } ], "pmid": "" } ], "biological_process": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A9JR78", "url": "https://www.uniprot.org/uniprotkb/A9JR78" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "A9JR78", "url": "https://www.uniprot.org/uniprotkb/A9JR78" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9JRB3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 476, "chemical_mass": 51122.0, "gene_names": "htra1b;htra1b;zgc:172061", "protein_name": "Serine protease HTRA1B", "disease": [ { "disease_id": "DOID:0050661", "name": "vitelliform macular dystrophy", "description": "A macular degeneration that it is characterized by the disruption of cells in a small area near the center of the retina, the macula and may cause progressive vision loss.", "url": "https://disease-ontology.org/term/DOID:0050661", "evidence": [ { "id": "0050661", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050661" } ], "weight": 0.0 }, { "disease_id": "DOID:0060863", "name": "patterned macular dystrophy", "description": "A macular degeneration characterized by abnormal accumulation of lipofuscin in the retinal pigment epithelium in a distinct pattern, patterns include; reticular ('fishnet-like'), macroreticular ('spider-shaped'), and butterfly-shaped.", "url": "https://disease-ontology.org/term/DOID:0060863", "evidence": [ { "id": "0060863", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060863" } ], "weight": 0.0 }, { "disease_id": "DOID:0061228", "name": "autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 2", "description": "A CADASIL characterized by alopecia, spondylosis, and progressive motor dysfunction and dementia. Onset is usually in the second or third decade that has_material_basis_in homozygous or compound heterozygous mutation in the HTRA1 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0061228", "evidence": [ { "id": "0061228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061228" } ], "weight": 0.0 }, { "disease_id": "DOID:0110019", "name": "age related macular degeneration 7", "description": "An age related macular degeneration conferred by variation in the HTRA1 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0110019", "evidence": [ { "id": "0110019", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110019" } ], "weight": 0.0 }, { "disease_id": "DOID:0111036", "name": "autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 2", "description": "A CADASIL characterized by stroke, transient ischemic attacks, cognitive impairment, dementia, balance impairment, gait disturbance, headaches, and/or seizures associated with early confluent or confluent diffuse white matter hyperintensities that has_material_basis_in heterozygous mutation in the HTRA1 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0111036", "evidence": [ { "id": "0111036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111036" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10871", "name": "age related macular degeneration", "description": "A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.", "url": "https://disease-ontology.org/term/DOID:10871", "evidence": [ { "id": "10871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10871" } ], "weight": 0.0 }, { "disease_id": "DOID:10873", "name": "Kuhnt-Junius degeneration", "description": "", "url": "https://disease-ontology.org/term/DOID:10873", "evidence": [ { "id": "10873", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10873" } ], "weight": 0.0 }, { "disease_id": "DOID:1107", "name": "esophageal carcinoma", "description": "A esophageal cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1107", "evidence": [ { "id": "1107", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1107" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1790", "name": "malignant mesothelioma", "description": "A cell type cancer that has_material_basis_in mesothelial tissue that develops from the thin layer of tissue that covers many of the internal organs. Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.", "url": "https://disease-ontology.org/term/DOID:1790", "evidence": [ { "id": "1790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1790" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "pmid": "" }, { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "pmid": "" }, { "name": "programmed cell death", "id": "GO:0012501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012501", "evidence": [ { "database": "UniProtKB", "id": "A9JRB3", "url": "https://www.uniprot.org/uniprotkb/A9JRB3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9JRC7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 307, "chemical_mass": 35097.0, "gene_names": "ppp4cb;PP4C-B;ppp4cb;zgc:172126", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit B", "disease": [ { "disease_id": "DOID:0070311", "name": "oligoasthenoteratozoospermia", "description": "A form of male infertility that is characterized by a combination of low number or oligozoospermia, poor motility or asthenozoospermia, and abnormal shape or teratozoospermia of sperms. OAT is the most common cause of male subfertility.", "url": "https://disease-ontology.org/term/DOID:0070311", "evidence": [ { "id": "0070311", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070311" } ], "weight": 0.0 }, { "disease_id": "DOID:0070515", "name": "chromosome 16p11.2 deletion syndrome, 593-kb", "description": "A chromosomal deletion syndrome characterized by language delay and mild intellectual disability that has_material_basis_in partial deletion of a contiguous 593-kb region of chromosome 16p11.2 (chr16:29.5-30.1 Mb).", "url": "https://disease-ontology.org/term/DOID:0070515", "evidence": [ { "id": "0070515", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070515" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" }, { "name": "determination of ventral identity", "id": "GO:0048264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048264", "evidence": [ { "database": "UniProtKB", "id": "A9JRC7", "url": "https://www.uniprot.org/uniprotkb/A9JRC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9JRZ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 765, "chemical_mass": 87464.0, "gene_names": "smurf2;smurf2;wu:fb82a11;wu:fc41c02", "protein_name": "E3 ubiquitin-protein ligase SMURF2", "disease": [ { "disease_id": "DOID:0050745", "name": "diffuse large B-cell lymphoma", "description": "A large B-cell lymphoma that is consisting of medium-sized to large B cells with a diffuse growth pattern.", "url": "https://disease-ontology.org/term/DOID:0050745", "evidence": [ { "id": "0050745", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050745" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "A9JRZ0", "url": "https://www.uniprot.org/uniprotkb/A9JRZ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9JTG5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 714, "chemical_mass": 78912.0, "gene_names": "rbck1;HOIL-1;rbck1;shrprbck1r;zgc:175152;zgc:91964", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "disease": [ { "disease_id": "DOID:2747", "name": "glycogen storage disease", "description": "A glycogen metabolism disorder that has_material_basis_in enzymes deficiencies necessary in the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types.", "url": "https://disease-ontology.org/term/DOID:2747", "evidence": [ { "id": "2747", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2747" } ], "weight": 0.0 }, { "disease_id": "DOID:3310", "name": "atopic dermatitis", "description": "An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.", "url": "https://disease-ontology.org/term/DOID:3310", "evidence": [ { "id": "3310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3310" } ], "weight": 0.0 } ], "biological_process": [ { "name": "protein linear polyubiquitination", "id": "GO:0097039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097039", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "embryonic cranial skeleton morphogenesis", "id": "GO:0048701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048701", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "otic vesicle morphogenesis", "id": "GO:0071600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071600", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "positive regulation of metabolic process", "id": "GO:0009893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009893", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" } ], "cellular_component": [ { "name": "LUBAC complex", "id": "GO:0071797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071797", "evidence": [ { "database": "UniProtKB", "id": "A9JTG5", "url": "https://www.uniprot.org/uniprotkb/A9JTG5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0JYH6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 541, "chemical_mass": 60113.0, "gene_names": "nectin1b;nectin1b;pvrl1b", "protein_name": "Nectin 1b", "disease": [ { "disease_id": "DOID:0060773", "name": "cleft lip-palate-ectodermal dysplasia syndrome", "description": "A syndrome characterized by cleft lip, cleft palate, hypodontia, anodontia, microdontia, syndactyly, palmoplantar hyperkeratosis, onychodysplasia, and sparse hair that has_material_basis_in homozygous mutation in the NECTIN1 gene on chromosome 11q23.", "url": "https://disease-ontology.org/term/DOID:0060773", "evidence": [ { "id": "0060773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060773" } ], "weight": 0.0 }, { "disease_id": "DOID:2121", "name": "ectodermal dysplasia", "description": "A syndrome characterized by abnormal development in 2 or more ectodermal structures (hair, nails, teeth, and sweat glands) without other systemic findings.", "url": "https://disease-ontology.org/term/DOID:2121", "evidence": [ { "id": "2121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2121" } ], "weight": 0.0 }, { "disease_id": "DOID:674", "name": "cleft palate", "description": "An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.", "url": "https://disease-ontology.org/term/DOID:674", "evidence": [ { "id": "674", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:674" } ], "weight": 0.0 }, { "disease_id": "DOID:9296", "name": "cleft lip", "description": "An orofacial cleft that is characterized by a congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences.", "url": "https://disease-ontology.org/term/DOID:9296", "evidence": [ { "id": "9296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9296" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "pmid": "" } ], "molecular_function": [ { "name": "virus receptor activity", "id": "GO:0001618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001618", "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "pmid": "" }, { "name": "cell adhesion mediator activity", "id": "GO:0098631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098631", "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "pmid": "" } ], "biological_process": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "pmid": "" }, { "name": "protein localization to cell junction", "id": "GO:1902414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902414", "evidence": [ { "database": "UniProtKB", "id": "B0JYH6", "url": "https://www.uniprot.org/uniprotkb/B0JYH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0JYH6-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Asn105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 105, "start_aa": "Asn", "end_pos": 105, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn105", "evidence": [ { "id": "B0JYH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JYH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "B0JYH6-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Asn180", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 180, "start_aa": "Asn", "end_pos": 180, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn180", "evidence": [ { "id": "B0JYH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JYH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "B0JYH6-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Asn242", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 242, "start_aa": "Asn", "end_pos": 242, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn242", "evidence": [ { "id": "B0JYH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JYH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "B0JYH6-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Asn326", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 326, "start_aa": "Asn", "end_pos": 326, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn326", "evidence": [ { "id": "B0JYH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JYH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "B0JYH6-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Asn337", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 337, "start_aa": "Asn", "end_pos": 337, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn337", "evidence": [ { "id": "B0JYH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JYH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "B0JYH6-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Asn372", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 372, "start_aa": "Asn", "end_pos": 372, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn372", "evidence": [ { "id": "B0JYH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JYH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "B0JYH6-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Asn51", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 51, "start_aa": "Asn", "end_pos": 51, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn51", "evidence": [ { "id": "B0JYH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JYH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R0B1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 366, "chemical_mass": 41019.0, "gene_names": "cbwd;zng1;cbwd;fb76b04;fc73a04;wu:fb76b04;wu:fc73a04;zgc:77617;zng1", "protein_name": "Zinc-regulated GTPase metalloprotein activator 1", "disease": [ { "disease_id": "DOID:0080205", "name": "congenital anomalies of the kidney and urinary tract", "description": "A urinary system disease characterized by structural malformations in the kidney and/or urinary tract containing vesicoureteral reflux.", "url": "https://disease-ontology.org/term/DOID:0080205", "evidence": [ { "id": "0080205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080205" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" }, { "name": "zinc chaperone activity", "id": "GO:0140827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140827", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "B0R0B1", "url": "https://www.uniprot.org/uniprotkb/B0R0B1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0R0B1-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Thr21", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R0D7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 474, "chemical_mass": 53368.0, "gene_names": "coro1ca;cb655;coro1ca;coro1c;wu:fa99e02;wu:fb30g03;wu:fc60a02;wu:fi35a01;zC108C6.3;zC191D15.1", "protein_name": "Coronin-1C-A", "disease": [ { "disease_id": "DOID:0070515", "name": "chromosome 16p11.2 deletion syndrome, 593-kb", "description": "A chromosomal deletion syndrome characterized by language delay and mild intellectual disability that has_material_basis_in partial deletion of a contiguous 593-kb region of chromosome 16p11.2 (chr16:29.5-30.1 Mb).", "url": "https://disease-ontology.org/term/DOID:0070515", "evidence": [ { "id": "0070515", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070515" } ], "weight": 0.0 }, { "disease_id": "DOID:13207", "name": "proliferative diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:13207", "evidence": [ { "id": "13207", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13207" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "endosome membrane tubulation", "id": "GO:0097750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097750", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" }, { "name": "endosome fission", "id": "GO:0140285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140285", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "B0R0D7", "url": "https://www.uniprot.org/uniprotkb/B0R0D7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0R0D7-1", "start_pos": "432", "end_pos": "432", "site_lbl": "Thr432", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 432, "start_aa": "Thr", "end_pos": 432, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr432", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R182-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 480, "chemical_mass": 54650.0, "gene_names": "p2rx5;p2rx5;p2x5", "protein_name": "P2X purinoceptor", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "pmid": "" }, { "name": "purinergic nucleotide receptor activity", "id": "GO:0001614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001614", "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "pmid": "" }, { "name": "extracellularly ATP-gated monoatomic cation channel activity", "id": "GO:0004931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004931", "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "pmid": "" } ], "biological_process": [ { "name": "monoatomic cation transport", "id": "GO:0006812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006812", "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "pmid": "" }, { "name": "response to ATP", "id": "GO:0033198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033198", "evidence": [ { "database": "UniProtKB", "id": "B0R182", "url": "https://www.uniprot.org/uniprotkb/B0R182" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0R182-1", "start_pos": "182", "end_pos": "182", "site_lbl": "Asn182", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 182, "start_aa": "Asn", "end_pos": 182, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn182", "evidence": [ { "id": "B0R182", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R182#ptm_processing" }, { "id": "PIRSR005713-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR005713-3" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0S576-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 640, "chemical_mass": 71239.0, "gene_names": "tp73;TAp73;sb:eu652;tp73;zp73theta", "protein_name": "Cellular tumor antigen p53", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0060081", "name": "triple-receptor negative breast cancer", "description": "A breast cancer that is characterized by the absence of estrogen, progresterone and Her2 receptors.", "url": "https://disease-ontology.org/term/DOID:0060081", "evidence": [ { "id": "0060081", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060081" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10286", "name": "prostate carcinoma", "description": "A prostate cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:10286", "evidence": [ { "id": "10286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10286" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10754", "name": "otitis media", "description": "A otitis which involves inflammation of the middle ear.", "url": "https://disease-ontology.org/term/DOID:10754", "evidence": [ { "id": "10754", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10754" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11132", "name": "prostatic hypertrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:11132", "evidence": [ { "id": "11132", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11132" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:2938", "name": "Epstein-Barr virus infectious disease", "description": "A viral infectious disease that has_material_basis_in Human gammaherpesvirus 4 (Lymphocryptovirus humangamma4).", "url": "https://disease-ontology.org/term/DOID:2938", "evidence": [ { "id": "2938", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2938" } ], "weight": 0.0 }, { "disease_id": "DOID:2998", "name": "testicular cancer", "description": "A male reproductive system cancer that is located_in the testicles.", "url": "https://disease-ontology.org/term/DOID:2998", "evidence": [ { "id": "2998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2998" } ], "weight": 0.0 }, { "disease_id": "DOID:3007", "name": "breast ductal carcinoma", "description": "A breast carcinoma that derives_from the lining of milk ducts.", "url": "https://disease-ontology.org/term/DOID:3007", "evidence": [ { "id": "3007", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3007" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:657", "name": "adenoma", "description": "A cell type benign neoplasm that is composed_of epithelial tissue in which tumor cells form glands or glandlike structures.", "url": "https://disease-ontology.org/term/DOID:657", "evidence": [ { "id": "657", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:657" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8991", "name": "cervix uteri carcinoma in situ", "description": "An uterus carcinoma in situ that is located_in the uterine cervix.", "url": "https://disease-ontology.org/term/DOID:8991", "evidence": [ { "id": "8991", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8991" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "biological_process": [ { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "protein tetramerization", "id": "GO:0051262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051262", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:0042771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042771", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "embryonic cranial skeleton morphogenesis", "id": "GO:0048701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048701", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "B0S576", "url": "https://www.uniprot.org/uniprotkb/B0S576" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0S576-1", "start_pos": "102", "end_pos": "102", "site_lbl": "Thr102", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 102, "start_aa": "Thr", "end_pos": 102, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr102", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0S789-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 725, "chemical_mass": 83742.0, "gene_names": "stat1b;STAT1;STAT;si:by134g18.3;si:by51f19.2;si:dz199m19.1;si:dz199m19.2;si:dz73o4.3;si:dz87i4.1;si:xx-51f19.2;stat1b;wu:fi49f02;zgc:55503", "protein_name": "Signal transducer and activator of transcription", "disease": [ { "disease_id": "DOID:0111944", "name": "immunodeficiency 31B", "description": "A primary immunodeficiency disease characterized by impaired cellular responses to interferons A, B, and G resulting increased susceptibility to mycobacteria, Salmonella, and viruses that has_material_basis_in homozygous or compound heterozygous mutation in the STAT1 gene on chromosome 2q32.2.", "url": "https://disease-ontology.org/term/DOID:0111944", "evidence": [ { "id": "0111944", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111944" } ], "weight": 0.0 }, { "disease_id": "DOID:0111945", "name": "immunodeficiency 31A", "description": "A primary immunodeficiency disease characterized by impaired response to IFNG but not to INFA or IFNB resulting in increased susceptibility to mycobacterial infection that has_material_basis_in heterozygous mutation in the STAT1 gene on chromosome 2q32.2.", "url": "https://disease-ontology.org/term/DOID:0111945", "evidence": [ { "id": "0111945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111945" } ], "weight": 0.0 }, { "disease_id": "DOID:0111946", "name": "immunodeficiency 31C", "description": "A primary immunodeficiency disease characterized by onset in infancy or childhood of chronic mucocutaneous candidiasis and increased IFNG activation that has_material_basis_in heterozygous gain of function mutation in the STAT1 gene on chromosome 2q32.2.", "url": "https://disease-ontology.org/term/DOID:0111946", "evidence": [ { "id": "0111946", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111946" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:1883", "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:2526", "name": "prostate adenocarcinoma", "description": "A prostate carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2526", "evidence": [ { "id": "2526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2526" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:3314", "name": "angiomyolipoma", "description": "A cell type benign neoplasm that is primarily located in the kidneys but may be found in the lungs, liver or other organs and is derived from perivascular epithelioid cells.", "url": "https://disease-ontology.org/term/DOID:3314", "evidence": [ { "id": "3314", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3314" } ], "weight": 0.0 }, { "disease_id": "DOID:3319", "name": "lymphangioleiomyomatosis", "description": "A lung disease that is characterized by progressive cystic destruction of the lung and lymphatic abnormalities, frequently associated with renal angiomyolipomas.", "url": "https://disease-ontology.org/term/DOID:3319", "evidence": [ { "id": "3319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3319" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 } ], "biological_process": [ { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "defense response", "id": "GO:0006952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006952", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "type II interferon-mediated signaling pathway", "id": "GO:0060333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060333", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "type I interferon-mediated signaling pathway", "id": "GO:0060337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060337", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "response to peptide hormone", "id": "GO:0043434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043434", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "negative regulation of developmental process", "id": "GO:0051093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051093", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "ISGF3 complex", "id": "GO:0070721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070721", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "B0S789", "url": "https://www.uniprot.org/uniprotkb/B0S789" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0S7H1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S7H1", "url": "https://www.uniprot.org/uniprotkb/B0S7H1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 305, "chemical_mass": 33910.0, "gene_names": "pdxka;cb1056;fb10c12;pdxka;pdxkl;si:dkey-281i8.2;wu:fa55a03;wu:fb10c12;zgc:101900", "protein_name": "Pyridoxal kinase", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B0S7H1", "url": "https://www.uniprot.org/uniprotkb/B0S7H1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B0S7H1", "url": "https://www.uniprot.org/uniprotkb/B0S7H1" } ], "pmid": "" }, { "name": "pyridoxal kinase activity", "id": "GO:0008478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008478", "evidence": [ { "database": "UniProtKB", "id": "B0S7H1", "url": "https://www.uniprot.org/uniprotkb/B0S7H1" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "B0S7H1", "url": "https://www.uniprot.org/uniprotkb/B0S7H1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B0S7H1", "url": "https://www.uniprot.org/uniprotkb/B0S7H1" } ], "pmid": "" } ], "biological_process": [ { "name": "pyridoxal 5'-phosphate salvage", "id": "GO:0009443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009443", "evidence": [ { "database": "UniProtKB", "id": "B0S7H1", "url": "https://www.uniprot.org/uniprotkb/B0S7H1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0UXL7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 350, "chemical_mass": 39587.0, "gene_names": "im:7147072;si:dkeyp-13a3.3;zgc:110269", "protein_name": "Probable flap endonuclease 1 homolog", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "5'-3' exonuclease activity", "id": "GO:0008409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008409", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "5'-flap endonuclease activity", "id": "GO:0017108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017108", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "B0UXL7", "url": "https://www.uniprot.org/uniprotkb/B0UXL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0UXS0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 272, "chemical_mass": 30377.0, "gene_names": "hmox1a;fc27c04;hmox1a;hmox1;wu:fc27c04;zgc:65984", "protein_name": "Heme oxygenase", "disease": [ { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0050852", "name": "limb ischemia", "description": "An ischemia that is characterized by low blood supply to tissues in the limb due to interruption in the arterial blood supply.", "url": "https://disease-ontology.org/term/DOID:0050852", "evidence": [ { "id": "0050852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050852" } ], "weight": 0.0 }, { "disease_id": "DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:0051061", "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ], "weight": 0.0 }, { "disease_id": "DOID:0060180", "name": "colitis", "description": "An inflammatory bowel disease that involves inflammation located_in colon.", "url": "https://disease-ontology.org/term/DOID:0060180", "evidence": [ { "id": "0060180", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060180" } ], "weight": 0.0 }, { "disease_id": "DOID:0080177", "name": "hepatic veno-occlusive disease", "description": "A hepatic vascular disease that is characterized by obstruction of some of the small veins of the liver.", "url": "https://disease-ontology.org/term/DOID:0080177", "evidence": [ { "id": "0080177", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080177" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:10322", "name": "berylliosis", "description": "A pneumoconiosis that involves allergic response located_in lungs caused by inhalation of beryllium compounds.", "url": "https://disease-ontology.org/term/DOID:10322", "evidence": [ { "id": "10322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10322" } ], "weight": 0.0 }, { "disease_id": "DOID:10325", "name": "silicosis", "description": "A pneumoconiosis that is an inflammation and scarring of the upper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles.", "url": "https://disease-ontology.org/term/DOID:10325", "evidence": [ { "id": "10325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10325" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1073", "name": "renal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1073", "evidence": [ { "id": "1073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1073" } ], "weight": 0.0 }, { "disease_id": "DOID:10762", "name": "portal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:10762", "evidence": [ { "id": "10762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10762" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain.", "url": "https://disease-ontology.org/term/DOID:10923", "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ], "weight": 0.0 }, { "disease_id": "DOID:11123", "name": "IgA vasculitis", "description": "A hypersensitivity vasculitis that is characterized by purpura (purplish plaques), arthralgia, gastrointestinal upset, and/or glomerulonephritis, and may be related to increased immune response following an infection.", "url": "https://disease-ontology.org/term/DOID:11123", "evidence": [ { "id": "11123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11123" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12134", "name": "factor VIII deficiency", "description": "A hemophilia that has_material_basis_in Factor VIII deficiency, which results in the formation of fibrin deficient clots which makes coagulation much more prolonged.", "url": "https://disease-ontology.org/term/DOID:12134", "evidence": [ { "id": "12134", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12134" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12337", "name": "varicocele", "description": "", "url": "https://disease-ontology.org/term/DOID:12337", "evidence": [ { "id": "12337", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12337" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:12510", "name": "retinal ischemia", "description": "An ischemia that is characterized by restriction in blood supply to the retina.", "url": "https://disease-ontology.org/term/DOID:12510", "evidence": [ { "id": "12510", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12510" } ], "weight": 0.0 }, { "disease_id": "DOID:12716", "name": "newborn respiratory distress syndrome", "description": "A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.", "url": "https://disease-ontology.org/term/DOID:12716", "evidence": [ { "id": "12716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12716" } ], "weight": 0.0 }, { "disease_id": "DOID:12894", "name": "Sjogren's syndrome", "description": "An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.", "url": "https://disease-ontology.org/term/DOID:12894", "evidence": [ { "id": "12894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12894" } ], "weight": 0.0 }, { "disease_id": "DOID:13100", "name": "intracranial vasospasm", "description": "", "url": "https://disease-ontology.org/term/DOID:13100", "evidence": [ { "id": "13100", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13100" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:13413", "name": "hepatic encephalopathy", "description": "A brain disease that is characterized by loss of brain function, the occurrence of confusion, altered level of consciousness, and coma that results when the liver is unable to remove toxins from the blood.", "url": "https://disease-ontology.org/term/DOID:13413", "evidence": [ { "id": "13413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13413" } ], "weight": 0.0 }, { "disease_id": "DOID:14115", "name": "toxic shock syndrome", "description": "A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.", "url": "https://disease-ontology.org/term/DOID:14115", "evidence": [ { "id": "14115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14115" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1584", "name": "acute chest syndrome", "description": "A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph.", "url": "https://disease-ontology.org/term/DOID:1584", "evidence": [ { "id": "1584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1584" } ], "weight": 0.0 }, { "disease_id": "DOID:1673", "name": "pneumothorax", "description": "A pleural disease that is characterized as an abnormal collection of air in the pleural space between the lung and the chest wall.", "url": "https://disease-ontology.org/term/DOID:1673", "evidence": [ { "id": "1673", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1673" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2352", "name": "hemochromatosis", "description": "A metal metabolism disorder characterized by the accumulation of iron in various organs of the body.", "url": "https://disease-ontology.org/term/DOID:2352", "evidence": [ { "id": "2352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2352" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:299", "name": "adenocarcinoma", "description": "A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue.", "url": "https://disease-ontology.org/term/DOID:299", "evidence": [ { "id": "299", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:299" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:4247", "name": "coronary restenosis", "description": "", "url": "https://disease-ontology.org/term/DOID:4247", "evidence": [ { "id": "4247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4247" } ], "weight": 0.0 }, { "disease_id": "DOID:4724", "name": "brain edema", "description": "A brain disease that is characterized by excess accumulation of fluid in the intracellular and/or extracellular spaces of the brain, has_symptom nausea, has_symptom vomiting, has_symptom blurred vision, has_symptom seizure, has_symptom coma.", "url": "https://disease-ontology.org/term/DOID:4724", "evidence": [ { "id": "4724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4724" } ], "weight": 0.0 }, { "disease_id": "DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:5041", "evidence": [ { "id": "5041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5041" } ], "weight": 0.0 }, { "disease_id": "DOID:5453", "name": "pulmonary venoocclusive disease", "description": "A pulmonary hypertension that is characterized by pulmonary venous constriction or occlusion, resulting in pulmonary hypertension.", "url": "https://disease-ontology.org/term/DOID:5453", "evidence": [ { "id": "5453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5453" } ], "weight": 0.0 }, { "disease_id": "DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.", "url": "https://disease-ontology.org/term/DOID:552", "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:750", "name": "peptic ulcer disease", "description": "", "url": "https://disease-ontology.org/term/DOID:750", "evidence": [ { "id": "750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:750" } ], "weight": 0.0 }, { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 }, { "disease_id": "DOID:8440", "name": "ileus", "description": "", "url": "https://disease-ontology.org/term/DOID:8440", "evidence": [ { "id": "8440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8440" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 }, { "disease_id": "DOID:900", "name": "hepatopulmonary syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:900", "evidence": [ { "id": "900", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:900" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9146", "name": "visceral leishmaniasis", "description": "A leishmaniasis that is the most severe form of the disease caused by protozoan parasites of the Leishmania genus, resulting in the infection of the internal organs such as liver, spleen and bone marrow. The symptoms include fever, weight loss, and an enlarged spleen and liver.", "url": "https://disease-ontology.org/term/DOID:9146", "evidence": [ { "id": "9146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9146" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "regulation of respiratory gaseous exchange", "id": "GO:0043576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043576", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "heme catabolic process", "id": "GO:0042167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042167", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "regulation of reactive oxygen species biosynthetic process", "id": "GO:1903426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903426", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "heme oxidation", "id": "GO:0006788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006788", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "regulation of macrophage migration", "id": "GO:1905521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905521", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "regulation of granuloma formation", "id": "GO:0002631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002631", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" }, { "name": "heme oxygenase (decyclizing) activity", "id": "GO:0004392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004392", "evidence": [ { "database": "UniProtKB", "id": "B0UXS0", "url": "https://www.uniprot.org/uniprotkb/B0UXS0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QDV5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QDV5", "url": "https://www.uniprot.org/uniprotkb/E9QDV5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 556, "chemical_mass": 60544.0, "gene_names": "ggt5a;ggt5a;ggt5", "protein_name": "Glutathione hydrolase", "disease": [], "biological_process": [ { "name": "glutathione catabolic process", "id": "GO:0006751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006751", "evidence": [ { "database": "UniProtKB", "id": "E9QDV5", "url": "https://www.uniprot.org/uniprotkb/E9QDV5" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "E9QDV5", "url": "https://www.uniprot.org/uniprotkb/E9QDV5" } ], "pmid": "" }, { "name": "leukotriene D4 biosynthetic process", "id": "GO:1901750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901750", "evidence": [ { "database": "UniProtKB", "id": "E9QDV5", "url": "https://www.uniprot.org/uniprotkb/E9QDV5" } ], "pmid": "" } ], "molecular_function": [ { "name": "glutathione hydrolase activity", "id": "GO:0036374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036374", "evidence": [ { "database": "UniProtKB", "id": "E9QDV5", "url": "https://www.uniprot.org/uniprotkb/E9QDV5" } ], "pmid": "" }, { "name": "leukotriene C4 gamma-glutamyl transferase activity", "id": "GO:0103068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0103068", "evidence": [ { "database": "UniProtKB", "id": "E9QDV5", "url": "https://www.uniprot.org/uniprotkb/E9QDV5" } ], "pmid": "" }, { "name": "leukotriene-C(4) hydrolase", "id": "GO:0002951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002951", "evidence": [ { "database": "UniProtKB", "id": "E9QDV5", "url": "https://www.uniprot.org/uniprotkb/E9QDV5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9QDV5", "url": "https://www.uniprot.org/uniprotkb/E9QDV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P43446-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 442, "chemical_mass": 50047.0, "gene_names": "wnt10a;WNT-10A;wnt-10a", "protein_name": "Protein Wnt-10a", "disease": [ { "disease_id": "DOID:0050591", "name": "tooth agenesis", "description": "A tooth disease characterized by failure to develop one or more missing teeth.", "url": "https://disease-ontology.org/term/DOID:0050591", "evidence": [ { "id": "0050591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050591" } ], "weight": 0.0 }, { "disease_id": "DOID:0111647", "name": "Schopf-Schulz-Passarge syndrome", "description": "An ectodermal dysplasia characterized by multiple eyelid apocrine hidrocystomas, palmoplantar keratoderma, hypotrichosis, hypodontia and nail dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the WNT10A gene on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:0111647", "evidence": [ { "id": "0111647", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111647" } ], "weight": 0.0 }, { "disease_id": "DOID:2121", "name": "ectodermal dysplasia", "description": "A syndrome characterized by abnormal development in 2 or more ectodermal structures (hair, nails, teeth, and sweat glands) without other systemic findings.", "url": "https://disease-ontology.org/term/DOID:2121", "evidence": [ { "id": "2121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2121" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" }, { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" }, { "name": "odontogenesis", "id": "GO:0042476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042476", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" }, { "name": "cell fate commitment", "id": "GO:0045165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P43446-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Asn143", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 143, "start_aa": "Asn", "end_pos": 143, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn143", "evidence": [ { "id": "P43446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43446#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43446-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Asn388", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 388, "start_aa": "Asn", "end_pos": 388, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn388", "evidence": [ { "id": "P43446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43446#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P43446-1", "start_pos": "248", "end_pos": "248", "site_lbl": "Gly248", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "S", "comment": "Strongly decreases the ability to induce the expression of genes involved in tooth development.", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" }, { "database": "PubMed", "id": "29178643", "url": "https://glygen.org/publication/PubMed/29178643" } ] } ] }, { "uniprot_canonical_ac": "P43446-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Thr382", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "I", "comment": "No significant effect on the ability to induce the expression of genes involved in tooth development.", "evidence": [ { "database": "UniProtKB", "id": "P43446", "url": "https://www.uniprot.org/uniprotkb/P43446" }, { "database": "PubMed", "id": "29178643", "url": "https://glygen.org/publication/PubMed/29178643" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0V237-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1103, "chemical_mass": 126079.0, "gene_names": "jak3;jak3", "protein_name": "Tyrosine-protein kinase", "disease": [ { "disease_id": "DOID:0050458", "name": "juvenile myelomonocytic leukemia", "description": "A myelodysplastic/myeloproliferative neoplasm that is characterized by the uncontrolled growth of monocytes.", "url": "https://disease-ontology.org/term/DOID:0050458", "evidence": [ { "id": "0050458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050458" } ], "weight": 0.0 }, { "disease_id": "DOID:0050523", "name": "adult T-cell leukemia/lymphoma", "description": "A T-cell acute leukemia that results_in abnormal increase of lymphocytes, derives_from T-cells, has_material_basis_in human T-cell leukemia virus type 1 (Deltaretrovirus priTlym1), which is transmitted_by sexual contact, transmitted_by contaminated needles used by intravenous-drug users, and transmitted_by breast feeding. The infection results_in_formation_of skin lesions.", "url": "https://disease-ontology.org/term/DOID:0050523", "evidence": [ { "id": "0050523", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050523" } ], "weight": 0.0 }, { "disease_id": "DOID:0081042", "name": "T-cell prolymphocytic leukemia", "description": "A prolymphocytic leukemia that is characterized by the proliferation of small to medium sized prolymphocytes with a mature T-cell phenotype, involving the blood, bone marrow, lymph nodes, liver, spleen, and skin.", "url": "https://disease-ontology.org/term/DOID:0081042", "evidence": [ { "id": "0081042", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081042" } ], "weight": 0.0 }, { "disease_id": "DOID:0081312", "name": "T-cell non-Hodgkin lymphoma", "description": "A non-Hodgkin lymphoma of T-cell lineage.", "url": "https://disease-ontology.org/term/DOID:0081312", "evidence": [ { "id": "0081312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081312" } ], "weight": 0.0 }, { "disease_id": "DOID:0090014", "name": "severe combined immunodeficiency 104", "description": "A severe combined immunodeficiency that is characterized by the onset of recurrent infections in early infancy and that has_material_basis_in homozygous or compound heterozygous mutation in the interleukin-7 receptor gene (IL7R) on chromosome 5p13.", "url": "https://disease-ontology.org/term/DOID:0090014", "evidence": [ { "id": "0090014", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090014" } ], "weight": 0.0 }, { "disease_id": "DOID:5603", "name": "T-cell acute lymphoblastic leukemia", "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood.", "url": "https://disease-ontology.org/term/DOID:5603", "evidence": [ { "id": "5603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5603" } ], "weight": 0.0 }, { "disease_id": "DOID:627", "name": "severe combined immunodeficiency", "description": "A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems.", "url": "https://disease-ontology.org/term/DOID:627", "evidence": [ { "id": "627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:627" } ], "weight": 0.0 }, { "disease_id": "DOID:8761", "name": "acute megakaryocytic leukemia", "description": "An acute myeloid leukemia that derives from blood-forming tissue in which megakaryocytes proliferate in the bone marrow and circulate in the blood in large numbers.", "url": "https://disease-ontology.org/term/DOID:8761", "evidence": [ { "id": "8761", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8761" } ], "weight": 0.0 } ], "biological_process": [ { "name": "natural killer cell differentiation", "id": "GO:0001779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001779", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "regulation of cell-cell adhesion", "id": "GO:0022407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022407", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "T cell differentiation in thymus", "id": "GO:0033077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033077", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "growth hormone receptor signaling pathway via JAK-STAT", "id": "GO:0060397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060397", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "lymphocyte differentiation", "id": "GO:0030098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030098", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "regulation of cell activation", "id": "GO:0050865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050865", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" } ], "molecular_function": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "growth hormone receptor binding", "id": "GO:0005131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005131", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B0V237", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0V2S2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 571, "chemical_mass": 64185.0, "gene_names": "dclre1b;dclre1b;im:6894074;si:dkey-73i4.1;snm1b;zgc:154089", "protein_name": "5' exonuclease Apollo", "disease": [ { "disease_id": "DOID:2729", "name": "dyskeratosis congenita", "description": "A skin disease characterized by cutaneous pigmentation, premature graying, dystrophy of the nails, leukoplakia of the oral mucosa, continuous lacrimation due to atresia of the lacrimal ducts, often thrombocytopenia, anemia, testicular atrophy in the male carriers and predisposition to cancer.", "url": "https://disease-ontology.org/term/DOID:2729", "evidence": [ { "id": "2729", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2729" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" } ], "molecular_function": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "5'-3' DNA exonuclease activity", "id": "GO:0035312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035312", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "5'-3' exonuclease activity", "id": "GO:0008409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008409", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "beta-lactamase activity", "id": "GO:0008800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008800", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" } ], "biological_process": [ { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "protection from non-homologous end joining at telomere", "id": "GO:0031848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031848", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "telomeric loop formation", "id": "GO:0031627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031627", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" }, { "name": "telomeric 3' overhang formation", "id": "GO:0031860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031860", "evidence": [ { "database": "UniProtKB", "id": "B0V2S2", "url": "https://www.uniprot.org/uniprotkb/B0V2S2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0V2X9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 645, "chemical_mass": 73155.0, "gene_names": "man1a2;fj20e02;man1a2;si:dkey-174k18.8;wu:fj20e02", "protein_name": "alpha-1,2-Mannosidase", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" }, { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" }, { "name": "intrahepatic bile duct development", "id": "GO:0035622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035622", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" }, { "name": "determination of pancreatic left/right asymmetry", "id": "GO:0035469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035469", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" }, { "name": "determination of heart left/right asymmetry", "id": "GO:0061371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061371", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" }, { "name": "determination of liver left/right asymmetry", "id": "GO:0071910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071910", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" }, { "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "id": "GO:0004571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004571", "evidence": [ { "database": "UniProtKB", "id": "B0V2X9", "url": "https://www.uniprot.org/uniprotkb/B0V2X9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0V3R4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 625, "chemical_mass": 69872.0, "gene_names": "slc6a6a;si:ch73-250d21.2;slc6a6a", "protein_name": "Transporter", "disease": [ { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:4752", "name": "multiple system atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:4752", "evidence": [ { "id": "4752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4752" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "gamma-aminobutyric acid:sodium:chloride symporter activity", "id": "GO:0005332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005332", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" }, { "name": "taurine:sodium symporter activity", "id": "GO:0005369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005369", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" }, { "name": "taurine transmembrane transport", "id": "GO:0015734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015734", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" }, { "name": "neurotransmitter transport", "id": "GO:0006836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006836", "evidence": [ { "database": "UniProtKB", "id": "B0V3R4", "url": "https://www.uniprot.org/uniprotkb/B0V3R4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B1H1H3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B1H1H3", "url": "https://www.uniprot.org/uniprotkb/B1H1H3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 263, "chemical_mass": 30916.0, "gene_names": "zdhhc21;dhcc21;zdhhc21;zgc:158420", "protein_name": "Palmitoyltransferase ZDHHC21", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "B1H1H3", "url": "https://www.uniprot.org/uniprotkb/B1H1H3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "B1H1H3", "url": "https://www.uniprot.org/uniprotkb/B1H1H3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "B1H1H3", "url": "https://www.uniprot.org/uniprotkb/B1H1H3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B1H1H3", "url": "https://www.uniprot.org/uniprotkb/B1H1H3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "B1H1H3", "url": "https://www.uniprot.org/uniprotkb/B1H1H3" } ], "pmid": "" }, { "name": "peptidyl-L-cysteine S-palmitoylation", "id": "GO:0018230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018230", "evidence": [ { "database": "UniProtKB", "id": "B1H1H3", "url": "https://www.uniprot.org/uniprotkb/B1H1H3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "B1H1H3", "url": "https://www.uniprot.org/uniprotkb/B1H1H3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B3DH96-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 325, "chemical_mass": 36713.0, "gene_names": "or131-2", "protein_name": "Odorant receptor 131-2", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" }, { "name": "intracellular membrane-bounded organelle", "id": "GO:0043231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" } ], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "B3DH96", "url": "https://www.uniprot.org/uniprotkb/B3DH96" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B3DH96-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Asn2", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2, "start_aa": "Asn", "end_pos": 2, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2", "evidence": [ { "id": "B3DH96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B3DH96#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "B3DH96-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Asn6", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 6, "start_aa": "Asn", "end_pos": 6, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn6", "evidence": [ { "id": "B3DH96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B3DH96#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B3DHS1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 206, "chemical_mass": 22904.0, "gene_names": "macir;zgc:194273;zgc:194281", "protein_name": "Macrophage immunometabolism regulator", "disease": [], "biological_process": [ { "name": "negative regulation of fibroblast migration", "id": "GO:0010764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010764", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "regulation of wound healing", "id": "GO:0061041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061041", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "Kupffer's vesicle development", "id": "GO:0070121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070121", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "negative regulation of macrophage chemotaxis", "id": "GO:0010760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010760", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "regulation of macrophage migration", "id": "GO:1905521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905521", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "B3DHS1", "url": "https://www.uniprot.org/uniprotkb/B3DHS1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B3DHU2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 212, "chemical_mass": 23070.0, "gene_names": "tmem65;tmem65;zgc:194294", "protein_name": "Transmembrane protein 65", "disease": [], "biological_process": [ { "name": "cardiac ventricle development", "id": "GO:0003231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003231", "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "pmid": "" }, { "name": "regulation of cardiac conduction", "id": "GO:1903779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903779", "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "pmid": "" }, { "name": "cardiac conduction", "id": "GO:0061337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061337", "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "pmid": "" }, { "name": "calcium export from the mitochondrion", "id": "GO:0099093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099093", "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B3DHU2", "url": "https://www.uniprot.org/uniprotkb/B3DHU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A4F4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1342, "chemical_mass": 150811.0, "gene_names": "tdrd9;si:dkey-15f17.9;tdrd9l;tdrd9", "protein_name": "ATP-dependent RNA helicase TDRD9", "disease": [ { "disease_id": "DOID:0111913", "name": "spermatogenic failure 30", "description": "A spermatogenic failure characterized by nonobstructive azoospermia or cryptozoospermia that has_material_basis_in homozygous or compound heterozygous mutation in the TDRD9 gene on chromosome 14q32.33.", "url": "https://disease-ontology.org/term/DOID:0111913", "evidence": [ { "id": "0111913", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111913" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "piP-body", "id": "GO:0071547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071547", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "transposable element silencing by piRNA-mediated heterochromatin formation", "id": "GO:0141006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141006", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "transposable element silencing by piRNA-mediated DNA methylation", "id": "GO:0141196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141196", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "B8A4F4", "url": "https://www.uniprot.org/uniprotkb/B8A4F4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A565-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 673, "chemical_mass": 72713.0, "gene_names": "c9;c9;wu:fb60b05;wu:fd50e04;zgc:112272", "protein_name": "Complement component C9", "disease": [ { "disease_id": "DOID:0060303", "name": "complement component 9 deficiency", "description": "A complement deficiency that is characterized by recurrent bacterial infections, has_material_basis_in mutation in the C9 gene.", "url": "https://disease-ontology.org/term/DOID:0060303", "evidence": [ { "id": "0060303", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060303" } ], "weight": 0.0 }, { "disease_id": "DOID:0110027", "name": "age related macular degeneration 15", "description": "An age related macular degeneration conferred by variation in the C9 gene on chromosome 5p13.", "url": "https://disease-ontology.org/term/DOID:0110027", "evidence": [ { "id": "0110027", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110027" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:898", "name": "autosomal dominant polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion.", "url": "https://disease-ontology.org/term/DOID:898", "evidence": [ { "id": "898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:898" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" }, { "name": "membrane attack complex", "id": "GO:0005579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005579", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" }, { "name": "other organism cell membrane", "id": "GO:0044218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044218", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" }, { "name": "killing of cells of another organism", "id": "GO:0031640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031640", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" }, { "name": "complement activation", "id": "GO:0006956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006956", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" }, { "name": "complement activation, alternative pathway", "id": "GO:0006957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006957", "evidence": [ { "database": "UniProtKB", "id": "B8A565", "url": "https://www.uniprot.org/uniprotkb/B8A565" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B8A565-1", "start_pos": "132", "end_pos": "132", "site_lbl": "Thr132", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 132, "start_aa": "Thr", "end_pos": 132, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr132", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A5G9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5G9", "url": "https://www.uniprot.org/uniprotkb/B8A5G9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 480, "chemical_mass": 54047.0, "gene_names": "trmt5;si:ch211-202m24.6;trm5;trmt5;wu:fi28b08", "protein_name": "tRNA (guanine(37)-N(1))-methyltransferase", "disease": [ { "disease_id": "DOID:0060536", "name": "mitochondrial complex I deficiency", "description": "A mitochondrial metabolism disease characterized by a wide range of manifestations including marked and often fatal lactic acidosis, cardiomyopathy, leukoencephalopathy, pure myopathy and hepatopathy with tubulopathy. Among the numerous clinical phenotypes observed are Leigh syndrome, Leber hereditary optic neuropathy and MELAS syndrome. It can have material basis in mutations in multiple different genes, both nuclear-encoded and mitochondrial-encoded.", "url": "https://disease-ontology.org/term/DOID:0060536", "evidence": [ { "id": "0060536", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060536" } ], "weight": 0.0 }, { "disease_id": "DOID:0111139", "name": "mitochondrial complex III deficiency", "description": "A mitochondrial metabolism disease characterized by impaired function of one or more of the proteins making up the mitochondrial respiratory chain complex III.", "url": "https://disease-ontology.org/term/DOID:0111139", "evidence": [ { "id": "0111139", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111139" } ], "weight": 0.0 }, { "disease_id": "DOID:0111490", "name": "combined oxidative phosphorylation deficiency 26", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the TRMT5 gene on chromosome 14q23.1.", "url": "https://disease-ontology.org/term/DOID:0111490", "evidence": [ { "id": "0111490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111490" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12678", "name": "hypercalcemia", "description": "", "url": "https://disease-ontology.org/term/DOID:12678", "evidence": [ { "id": "12678", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12678" } ], "weight": 0.0 }, { "disease_id": "DOID:3650", "name": "lactic acidosis", "description": "A metabolic acidosis characterized by buildup of lactate.", "url": "https://disease-ontology.org/term/DOID:3650", "evidence": [ { "id": "3650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3650" } ], "weight": 0.0 }, { "disease_id": "DOID:3762", "name": "cytochrome-c oxidase deficiency disease", "description": "A mitochondrial metabolism disease that is characterized by deficiency of cytochrome c oxidase, myopathy, hepatomegaly, hypertrophic cardiomyopathy, lactic acidosis, and Leigh syndrome, and is caused by mutations related to oxidative phosphorylation.", "url": "https://disease-ontology.org/term/DOID:3762", "evidence": [ { "id": "3762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3762" } ], "weight": 0.0 }, { "disease_id": "DOID:699", "name": "mitochondrial myopathy", "description": "A myopathy that is characterized by mitochondrial dysfunction.", "url": "https://disease-ontology.org/term/DOID:699", "evidence": [ { "id": "699", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:699" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "tRNA methyltransferase activity", "id": "GO:0008175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008175", "evidence": [ { "database": "UniProtKB", "id": "B8A5G9", "url": "https://www.uniprot.org/uniprotkb/B8A5G9" } ], "pmid": "" }, { "name": "tRNA (guanine(37)-N1)-methyltransferase activity", "id": "GO:0052906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052906", "evidence": [ { "database": "UniProtKB", "id": "B8A5G9", "url": "https://www.uniprot.org/uniprotkb/B8A5G9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8A5G9", "url": "https://www.uniprot.org/uniprotkb/B8A5G9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8A5G9", "url": "https://www.uniprot.org/uniprotkb/B8A5G9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "B8A5G9", "url": "https://www.uniprot.org/uniprotkb/B8A5G9" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA N1-guanine methylation", "id": "GO:0002939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002939", "evidence": [ { "database": "UniProtKB", "id": "B8A5G9", "url": "https://www.uniprot.org/uniprotkb/B8A5G9" } ], "pmid": "" }, { "name": "mitochondrial tRNA methylation", "id": "GO:0070901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070901", "evidence": [ { "database": "UniProtKB", "id": "B8A5G9", "url": "https://www.uniprot.org/uniprotkb/B8A5G9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A5K6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 957, "chemical_mass": 107797.0, "gene_names": "kitb;kitb", "protein_name": "Mast/stem cell growth factor receptor", "disease": [ { "disease_id": "DOID:10487", "name": "Hirschsprung's disease", "description": "A megacolon that is characterized by a blockage of the large intestine due to improper muscle movement in the bowel.", "url": "https://disease-ontology.org/term/DOID:10487", "evidence": [ { "id": "10487", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10487" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:1967", "name": "leiomyosarcoma", "description": "A smooth muscle cancer that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.", "url": "https://disease-ontology.org/term/DOID:1967", "evidence": [ { "id": "1967", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1967" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:2361", "name": "macrocytic anemia", "description": "An anemia that is characterized by the production of abnormally large red blood cells and mean corpuscular volume (MCV) (more than 100 fL).", "url": "https://disease-ontology.org/term/DOID:2361", "evidence": [ { "id": "2361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2361" } ], "weight": 0.0 }, { "disease_id": "DOID:2999", "name": "granulosa cell tumor", "description": "A sex cord-gonadal stromal tumor that has_material_basis_in granulosa cells and arises from the sex cord stroma.", "url": "https://disease-ontology.org/term/DOID:2999", "evidence": [ { "id": "2999", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2999" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3263", "name": "piebaldism", "description": "An integumentary system disease characterized by congenital absence of melanocytes in areas of the skin and hair that has_material_basis_in heterozygous mutation in the KIT gene on chromosome 4q12.", "url": "https://disease-ontology.org/term/DOID:3263", "evidence": [ { "id": "3263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3263" } ], "weight": 0.0 }, { "disease_id": "DOID:350", "name": "mastocytosis", "description": "", "url": "https://disease-ontology.org/term/DOID:350", "evidence": [ { "id": "350", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:350" } ], "weight": 0.0 }, { "disease_id": "DOID:4226", "name": "endometrial stromal sarcoma", "description": "An endometrial stromal tumor that has_material_basis_in connective tissue.", "url": "https://disease-ontology.org/term/DOID:4226", "evidence": [ { "id": "4226", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4226" } ], "weight": 0.0 }, { "disease_id": "DOID:4440", "name": "seminoma", "description": "A germinoma that has_material_basis_in cells that make sperm and eggs.", "url": "https://disease-ontology.org/term/DOID:4440", "evidence": [ { "id": "4440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4440" } ], "weight": 0.0 }, { "disease_id": "DOID:4441", "name": "dysgerminoma", "description": "A germ cell cancer that derives_from cells that give rise to egg cells.", "url": "https://disease-ontology.org/term/DOID:4441", "evidence": [ { "id": "4441", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4441" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5389", "name": "oxyphilic adenoma", "description": "", "url": "https://disease-ontology.org/term/DOID:5389", "evidence": [ { "id": "5389", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5389" } ], "weight": 0.0 }, { "disease_id": "DOID:6171", "name": "uterine carcinosarcoma", "description": "A uterine body mixed cancer that has_material_basis_in both endometrial carcinoma and sarcoma.", "url": "https://disease-ontology.org/term/DOID:6171", "evidence": [ { "id": "6171", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6171" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9253", "name": "gastrointestinal stromal tumor", "description": "", "url": "https://disease-ontology.org/term/DOID:9253", "evidence": [ { "id": "9253", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9253" } ], "weight": 0.0 }, { "disease_id": "DOID:962", "name": "neurofibroma", "description": "", "url": "https://disease-ontology.org/term/DOID:962", "evidence": [ { "id": "962", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:962" } ], "weight": 0.0 } ], "biological_process": [ { "name": "embryonic hemopoiesis", "id": "GO:0035162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035162", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "Fc receptor signaling pathway", "id": "GO:0038093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038093", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "positive regulation of receptor signaling pathway via JAK-STAT", "id": "GO:0046427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046427", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "hematopoietic progenitor cell differentiation", "id": "GO:0002244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "Kit signaling pathway", "id": "GO:0038109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038109", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "ameboidal-type cell migration", "id": "GO:0001667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001667", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "B8A5K6", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A5L6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 684, "chemical_mass": 75291.0, "gene_names": "fga;fga;sb:cb892;wu:fa55c12;wu:fb20e08;wu:fb59b03;wu:fi39d04;zgc:92117", "protein_name": "", "disease": [ { "disease_id": "DOID:0050636", "name": "hereditary systemic amyloidosis 2", "description": "An amyloidosis that is characterized by the abnormal deposition of amyloid proteins that is located_in the visceral organs, primarily the kidneys.", "url": "https://disease-ontology.org/term/DOID:0050636", "evidence": [ { "id": "0050636", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050636" } ], "weight": 0.0 }, { "disease_id": "DOID:0112313", "name": "brain small vessel disease", "description": "A brain disease characterized by abnormalities in the small blood vessels in the brain.", "url": "https://disease-ontology.org/term/DOID:0112313", "evidence": [ { "id": "0112313", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112313" } ], "weight": 0.0 }, { "disease_id": "DOID:10126", "name": "keratoconus", "description": "A corneal disease characterized by structural changes within the cornea causing it to thin and change, leading to a protruding conical shape.", "url": "https://disease-ontology.org/term/DOID:10126", "evidence": [ { "id": "10126", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10126" } ], "weight": 0.0 }, { "disease_id": "DOID:2236", "name": "congenital afibrinogenemia", "description": "A blood coagulation disease that is characterized by an impaired blood clotting resulting from a lack deficiency of a the fibrinogen protein (coagulation factor I).", "url": "https://disease-ontology.org/term/DOID:2236", "evidence": [ { "id": "2236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2236" } ], "weight": 0.0 }, { "disease_id": "DOID:2452", "name": "thrombophilia", "description": "A blood coagulation disease that is characterized by an increased tendency to form clots.", "url": "https://disease-ontology.org/term/DOID:2452", "evidence": [ { "id": "2452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2452" } ], "weight": 0.0 }, { "disease_id": "DOID:484", "name": "vascular hemostatic disease", "description": "", "url": "https://disease-ontology.org/term/DOID:484", "evidence": [ { "id": "484", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:484" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" } ], "biological_process": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" }, { "name": "fibrinolysis", "id": "GO:0042730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042730", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" }, { "name": "platelet aggregation", "id": "GO:0070527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070527", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" }, { "name": "positive regulation of blood coagulation", "id": "GO:0030194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030194", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" }, { "name": "protein polymerization", "id": "GO:0051258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051258", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" }, { "name": "blood coagulation, common pathway", "id": "GO:0072377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072377", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" }, { "name": "positive regulation of heterotypic cell-cell adhesion", "id": "GO:0034116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034116", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" }, { "name": "blood coagulation, fibrin clot formation", "id": "GO:0072378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072378", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" } ], "cellular_component": [ { "name": "fibrinogen complex", "id": "GO:0005577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005577", "evidence": [ { "database": "UniProtKB", "id": "B8A5L6", "url": "https://www.uniprot.org/uniprotkb/B8A5L6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A5N7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 563, "chemical_mass": 63638.0, "gene_names": "cdc25b;cdc25A;cdc25b;cdc25;sb:cb317", "protein_name": "M-phase inducer phosphatase", "disease": [ { "disease_id": "DOID:0080365", "name": "endometrial hyperplasia", "description": "An uterine benign neoplasm that is characterized by excessive proliferation of the cells of the endometrium.", "url": "https://disease-ontology.org/term/DOID:0080365", "evidence": [ { "id": "0080365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080365" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:2101", "name": "vulva squamous cell carcinoma", "description": "A vulva carcinoma and has_material_basis_in squamous cells and is located_in the epidermis of the vulvar tissue.", "url": "https://disease-ontology.org/term/DOID:2101", "evidence": [ { "id": "2101", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2101" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle", "id": "GO:0045931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045931", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" }, { "name": "regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010389", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle, embryonic", "id": "GO:0009794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009794", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" }, { "name": "positive regulation of G2/MI transition of meiotic cell cycle", "id": "GO:0110032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110032", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "B8A5N7", "url": "https://www.uniprot.org/uniprotkb/B8A5N7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A5W4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5W4", "url": "https://www.uniprot.org/uniprotkb/B8A5W4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 324, "chemical_mass": 35831.0, "gene_names": "dhrsx;dhrsx;pye", "protein_name": "Polyprenol dehydrogenase", "disease": [ { "disease_id": "DOID:14791", "name": "Leber congenital amaurosis", "description": "A retinal disease that is characterized by nystagmus, sluggish or no pupillary responses, and severe vision loss or blindness.", "url": "https://disease-ontology.org/term/DOID:14791", "evidence": [ { "id": "14791", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14791" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "B8A5W4", "url": "https://www.uniprot.org/uniprotkb/B8A5W4" } ], "pmid": "" } ], "biological_process": [ { "name": "dolichyl monophosphate biosynthetic process", "id": "GO:0043048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043048", "evidence": [ { "database": "UniProtKB", "id": "B8A5W4", "url": "https://www.uniprot.org/uniprotkb/B8A5W4" } ], "pmid": "" } ], "molecular_function": [ { "name": "polyprenol dehydrogenase (NAD+) activity", "id": "GO:0160196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160196", "evidence": [ { "database": "UniProtKB", "id": "B8A5W4", "url": "https://www.uniprot.org/uniprotkb/B8A5W4" } ], "pmid": "" }, { "name": "dolichal reductase (NADPH) activity", "id": "GO:0160197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160197", "evidence": [ { "database": "UniProtKB", "id": "B8A5W4", "url": "https://www.uniprot.org/uniprotkb/B8A5W4" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "B8A5W4", "url": "https://www.uniprot.org/uniprotkb/B8A5W4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A5Y1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 502, "chemical_mass": 56921.0, "gene_names": "znf488;prdm8;wu:fd12b11;zgc:63680;znf488", "protein_name": "Zinc finger protein 488", "disease": [], "biological_process": [ { "name": "spinal cord motor neuron cell fate specification", "id": "GO:0021520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021520", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" }, { "name": "oligodendrocyte development", "id": "GO:0014003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014003", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8A5Y1", "url": "https://www.uniprot.org/uniprotkb/B8A5Y1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8A697-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 674, "chemical_mass": 78361.0, "gene_names": "alox5a;alox5a;alox5;si:dkey-194n13.2", "protein_name": "", "disease": [ { "disease_id": "DOID:0080821", "name": "exercise-induced bronchoconstriction", "description": "An intrinsic asthma that is characterized by narrowing of the airways during or shortly after exercise.", "url": "https://disease-ontology.org/term/DOID:0080821", "evidence": [ { "id": "0080821", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080821" } ], "weight": 0.0 }, { "disease_id": "DOID:0080822", "name": "aspirin-induced respiratory disease", "description": "An intrinsic asthma that is characterized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs.", "url": "https://disease-ontology.org/term/DOID:0080822", "evidence": [ { "id": "0080822", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080822" } ], "weight": 0.0 }, { "disease_id": "DOID:10459", "name": "common cold", "description": "An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus.", "url": "https://disease-ontology.org/term/DOID:10459", "evidence": [ { "id": "10459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10459" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:8719", "name": "in situ carcinoma", "description": "A carcinoma that is an early development defined by the absence of invasion of surrounding tissues.", "url": "https://disease-ontology.org/term/DOID:8719", "evidence": [ { "id": "8719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8719" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "leukotriene-C4 synthase activity", "id": "GO:0004464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004464", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" }, { "name": "arachidonate 5-lipoxygenase activity", "id": "GO:0004051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004051", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" }, { "name": "arachidonate monooxygenase activity", "id": "GO:0008391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008391", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid oxidation", "id": "GO:0034440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034440", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" }, { "name": "lipoxygenase pathway", "id": "GO:0019372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019372", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" }, { "name": "arachidonate metabolic process", "id": "GO:0019369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019369", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" }, { "name": "inflammatory response to wounding", "id": "GO:0090594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090594", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8A697", "url": "https://www.uniprot.org/uniprotkb/B8A697" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JHS2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 382, "chemical_mass": 43002.0, "gene_names": "oprm1;ZFOR2;oprm1;or2", "protein_name": "Mu-type opioid receptor", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:11206", "name": "opioid abuse", "description": "A substance abuse that involves the recurring use of opioid drugs despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:11206", "evidence": [ { "id": "11206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11206" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1742", "name": "drug psychosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1742", "evidence": [ { "id": "1742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1742" } ], "weight": 0.0 }, { "disease_id": "DOID:2055", "name": "post-traumatic stress disorder", "description": "An anxiety disorder which results from a traumatic experience that results in psychological trauma.", "url": "https://disease-ontology.org/term/DOID:2055", "evidence": [ { "id": "2055", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2055" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:9828", "name": "neonatal abstinence syndrome", "description": "A withdrawal disorder that is characterized by a group of problems that occur in a newborn who was exposed to addictive illegal or prescription drugs while in the mother's womb or postnatally following the discontinuance of drug treatment.", "url": "https://disease-ontology.org/term/DOID:9828", "evidence": [ { "id": "9828", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9828" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9974", "name": "drug dependence", "description": "A substance dependence that involves the continued use of drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9974", "evidence": [ { "id": "9974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9974" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "G protein-coupled enkephalin receptor activity", "id": "GO:0038046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038046", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "morphine receptor activity", "id": "GO:0038047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038047", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "beta-endorphin receptor activity", "id": "GO:0004979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004979", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "neuropeptide binding", "id": "GO:0042923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042923", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" } ], "biological_process": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "sensory perception of pain", "id": "GO:0019233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019233", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" }, { "name": "G protein-coupled opioid receptor signaling pathway", "id": "GO:0038003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038003", "evidence": [ { "database": "UniProtKB", "id": "B8JHS2", "url": "https://www.uniprot.org/uniprotkb/B8JHS2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JIB4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JIB4", "url": "https://www.uniprot.org/uniprotkb/B8JIB4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 951, "chemical_mass": 109019.0, "gene_names": "enpep;enpep;im:7152184;si:ch211-146m5.2", "protein_name": "Aminopeptidase", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B8JIB4", "url": "https://www.uniprot.org/uniprotkb/B8JIB4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B8JIB4", "url": "https://www.uniprot.org/uniprotkb/B8JIB4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B8JIB4", "url": "https://www.uniprot.org/uniprotkb/B8JIB4" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "B8JIB4", "url": "https://www.uniprot.org/uniprotkb/B8JIB4" } ], "pmid": "" }, { "name": "glutamyl aminopeptidase activity", "id": "GO:0004230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004230", "evidence": [ { "database": "UniProtKB", "id": "B8JIB4", "url": "https://www.uniprot.org/uniprotkb/B8JIB4" } ], "pmid": "" } ], "biological_process": [ { "name": "angiotensin maturation", "id": "GO:0002003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002003", "evidence": [ { "database": "UniProtKB", "id": "B8JIB4", "url": "https://www.uniprot.org/uniprotkb/B8JIB4" } ], "pmid": "" }, { "name": "peptide catabolic process", "id": "GO:0043171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043171", "evidence": [ { "database": "UniProtKB", "id": "B8JIB4", "url": "https://www.uniprot.org/uniprotkb/B8JIB4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JIQ1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 419, "chemical_mass": 46802.0, "gene_names": "gsk3bb;gsk3bb;si:dkeyp-80c12.7", "protein_name": "Glycogen synthase kinase-3 beta", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:90", "name": "degenerative disc disease", "description": "A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc.", "url": "https://disease-ontology.org/term/DOID:90", "evidence": [ { "id": "90", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:90" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "beta-catenin destruction complex", "id": "GO:0030877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030877", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "B8JIQ1", "url": "https://www.uniprot.org/uniprotkb/B8JIQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B8JIQ1-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 43, "start_aa": "Thr", "end_pos": 43, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr43", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JKD7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1132, "chemical_mass": 127612.0, "gene_names": "polr1b", "protein_name": "DNA-directed RNA polymerase I subunit RPA2", "disease": [], "biological_process": [ { "name": "neural crest formation", "id": "GO:0014029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014029", "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase I", "id": "GO:0006362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006362", "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "pmid": "" }, { "name": "ribonucleoside binding", "id": "GO:0032549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032549", "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "pmid": "" } ], "cellular_component": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "pmid": "" }, { "name": "RNA polymerase I complex", "id": "GO:0005736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005736", "evidence": [ { "database": "UniProtKB", "id": "B8JKD7", "url": "https://www.uniprot.org/uniprotkb/B8JKD7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JKF4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 368, "chemical_mass": 42230.0, "gene_names": "stn1;dkey-100g3.3;obfc1;stn1;zgc:64174", "protein_name": "CST complex subunit STN1", "disease": [ { "disease_id": "DOID:1272", "name": "telangiectasis", "description": "", "url": "https://disease-ontology.org/term/DOID:1272", "evidence": [ { "id": "1272", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1272" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 } ], "biological_process": [ { "name": "telomere maintenance via telomere lengthening", "id": "GO:0010833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010833", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" }, { "name": "telomere capping", "id": "GO:0016233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016233", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" }, { "name": "CST complex", "id": "GO:1990879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990879", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" } ], "molecular_function": [ { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" }, { "name": "single-stranded telomeric DNA binding", "id": "GO:0043047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043047", "evidence": [ { "database": "UniProtKB", "id": "B8JKF4", "url": "https://www.uniprot.org/uniprotkb/B8JKF4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JL43-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 673, "chemical_mass": 73282.0, "gene_names": "tfa;cb285;gavi;id:ibd3238;id:ibd3525;sb:cb285;tfa;trf;wu:fb57g06;wu:fb62h02;wu:fb63h10;wu:fb64h10;zgc:112154", "protein_name": "Serotransferrin", "disease": [ { "disease_id": "DOID:0050425", "name": "restless legs syndrome", "description": "A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in the legs and the irresistible urge to move them.", "url": "https://disease-ontology.org/term/DOID:0050425", "evidence": [ { "id": "0050425", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050425" } ], "weight": 0.0 }, { "disease_id": "DOID:0050649", "name": "atransferrinemia", "description": "A metal metabolism disorder that is characterized by transferrin deficiency, microcytic anemia, and iron loading, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the structural gene for transferrin (TF) on chromosome 3q22.", "url": "https://disease-ontology.org/term/DOID:0050649", "evidence": [ { "id": "0050649", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050649" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:11758", "name": "iron deficiency anemia", "description": "A microcytic anemia that is characterized by pallor, fatigue, lightheadedness, and weakness and has_material_basis_in low total body iron causing impaired synthesis of red blood cells.", "url": "https://disease-ontology.org/term/DOID:11758", "evidence": [ { "id": "11758", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11758" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:77", "name": "gastrointestinal system disease", "description": "A disease of anatomical entity that is located_in the gastrointestinal tract.", "url": "https://disease-ontology.org/term/DOID:77", "evidence": [ { "id": "77", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:77" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" } ], "biological_process": [ { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" }, { "name": "hemoglobin biosynthetic process", "id": "GO:0042541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042541", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B8JL43", "url": "https://www.uniprot.org/uniprotkb/B8JL43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R6L6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 705, "chemical_mass": 75061.0, "gene_names": "ncl;fa12d03;ncl;nucleolin;wu:fa12d03;zgc:152810", "protein_name": "Nucleolin", "disease": [], "biological_process": [ { "name": "regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0040036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040036", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "rRNA transcription", "id": "GO:0009303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009303", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "regulation of cartilage development", "id": "GO:0061035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061035", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F1R6L6", "url": "https://www.uniprot.org/uniprotkb/F1R6L6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1R6L6-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Thr140", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 140, "start_aa": "Thr", "end_pos": 140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr140", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1R6L6-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Thr145", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 145, "start_aa": "Thr", "end_pos": 145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr145", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1R6L6-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Thr260", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JM40-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 403, "chemical_mass": 47164.0, "gene_names": "trmt10c;rg9mtd1;trmt10c;wu:fb53e06;zgc:103570", "protein_name": "tRNA methyltransferase 10 homolog C", "disease": [ { "disease_id": "DOID:0111471", "name": "combined oxidative phosphorylation deficiency 30", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the TRMT10C gene on chromosome 3q12.3.", "url": "https://disease-ontology.org/term/DOID:0111471", "evidence": [ { "id": "0111471", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111471" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" }, { "name": "tRNA (guanosine(9)-N1)-methyltransferase activity", "id": "GO:0052905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052905", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" }, { "name": "tRNA (adenine(9)-N1)-methyltransferase activity", "id": "GO:0160106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160106", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" } ], "biological_process": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial translation", "id": "GO:0070131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070131", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" }, { "name": "mitochondrial tRNA 5'-end processing", "id": "GO:0097745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097745", "evidence": [ { "database": "UniProtKB", "id": "B8JM40", "url": "https://www.uniprot.org/uniprotkb/B8JM40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JMI2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 676, "chemical_mass": 73823.0, "gene_names": "dvl3a;dvl3a;dvl3;wu:fb75f04;wu:fi22h02;wu:fp61b09", "protein_name": "", "disease": [ { "disease_id": "DOID:0060767", "name": "autosomal dominant Robinow syndrome 3", "description": "A Robinow syndrome characterized by autosomal dominant inheritance of mesomelia, genital hypoplasia, and distinctive facial features comprising frontal bossing, prominent eyes, and a depressed nasal bridge that has_material_basis_in heterozygous mutation in the DVL3 gene on chromosome 3q27.", "url": "https://disease-ontology.org/term/DOID:0060767", "evidence": [ { "id": "0060767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060767" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway, planar cell polarity pathway", "id": "GO:2000096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000096", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" }, { "name": "convergent extension involved in axis elongation", "id": "GO:0060028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060028", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" }, { "name": "post-anal tail morphogenesis", "id": "GO:0036342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036342", "evidence": [ { "database": "UniProtKB", "id": "B8JMI2", "url": "https://www.uniprot.org/uniprotkb/B8JMI2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "C0HJJ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "C0HJJ0", "url": "https://www.uniprot.org/uniprotkb/C0HJJ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 69, "chemical_mass": 7604.0, "gene_names": "fxyd11;fxyd11;hm:zeh0312;si:dkey-33i11.4;zeh0312", "protein_name": "FXYD domain-containing ion transport regulator 11", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "C0HJJ0", "url": "https://www.uniprot.org/uniprotkb/C0HJJ0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "C0HJJ0", "url": "https://www.uniprot.org/uniprotkb/C0HJJ0" } ], "pmid": "" } ], "biological_process": [ { "name": "monoatomic ion transport", "id": "GO:0006811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006811", "evidence": [ { "database": "UniProtKB", "id": "C0HJJ0", "url": "https://www.uniprot.org/uniprotkb/C0HJJ0" } ], "pmid": "" }, { "name": "positive regulation of sodium ion export across plasma membrane", "id": "GO:1903278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903278", "evidence": [ { "database": "UniProtKB", "id": "C0HJJ0", "url": "https://www.uniprot.org/uniprotkb/C0HJJ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "C0HJJ0", "url": "https://www.uniprot.org/uniprotkb/C0HJJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "C0HM54-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "C0HM54", "url": "https://www.uniprot.org/uniprotkb/C0HM54" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 539, "chemical_mass": 62482.0, "gene_names": "Scg2a;SgIIa", "protein_name": "Secretogranin-2a", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "C0HM54", "url": "https://www.uniprot.org/uniprotkb/C0HM54" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "C0HM54", "url": "https://www.uniprot.org/uniprotkb/C0HM54" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "C5H5C4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 500, "chemical_mass": 56715.0, "gene_names": "notum1a;notum1a;notum3", "protein_name": "Palmitoleoyl-protein carboxylesterase notum1a", "disease": [], "biological_process": [ { "name": "protein depalmitoleylation", "id": "GO:1990697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990697", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" }, { "name": "neural tube patterning", "id": "GO:0021532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021532", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" } ], "molecular_function": [ { "name": "palmitoleyl hydrolase activity", "id": "GO:1990699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990699", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" }, { "name": "glycosylphosphatidylinositol phospholipase D activity", "id": "GO:0004621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004621", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" }, { "name": "protein-containing complex destabilizing activity", "id": "GO:0140776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140776", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "C5H5C4", "url": "https://www.uniprot.org/uniprotkb/C5H5C4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "C5H5C4-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Asn101", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 101, "start_aa": "Asn", "end_pos": 101, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn101", "evidence": [ { "id": "C5H5C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C5H5C4#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "C7DZK3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "C7DZK3", "url": "https://www.uniprot.org/uniprotkb/C7DZK3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1783, "chemical_mass": 179841.0, "gene_names": "col27a1a;cb221;col27a1a;sb:cb221", "protein_name": "Collagen alpha-1(XXVII) chain A", "disease": [], "biological_process": [ { "name": "notochord morphogenesis", "id": "GO:0048570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048570", "evidence": [ { "database": "UniProtKB", "id": "C7DZK3", "url": "https://www.uniprot.org/uniprotkb/C7DZK3" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "C7DZK3", "url": "https://www.uniprot.org/uniprotkb/C7DZK3" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "C7DZK3", "url": "https://www.uniprot.org/uniprotkb/C7DZK3" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "C7DZK3", "url": "https://www.uniprot.org/uniprotkb/C7DZK3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "C7DZK3", "url": "https://www.uniprot.org/uniprotkb/C7DZK3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "C7DZK3", "url": "https://www.uniprot.org/uniprotkb/C7DZK3" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "C7DZK3", "url": "https://www.uniprot.org/uniprotkb/C7DZK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "C7DZK3-1", "start_pos": "1271", "end_pos": "1271", "site_lbl": "Thr1271", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1271, "start_aa": "Thr", "end_pos": 1271, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1271", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "C7DZK3-1", "start_pos": "1384", "end_pos": "1384", "site_lbl": "Thr1384", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1384, "start_aa": "Thr", "end_pos": 1384, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1384", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "C7DZK3-1", "start_pos": "1698", "end_pos": "1698", "site_lbl": "Asn1698", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1698, "start_aa": "Asn", "end_pos": 1698, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1698", "evidence": [ { "id": "C7DZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C7DZK3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "C7DZK3-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Thr356", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 356, "start_aa": "Thr", "end_pos": 356, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr356", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7EXP6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 799, "chemical_mass": 86703.0, "gene_names": "pan3;PAN3;pan3;zgc:171628", "protein_name": "PAN2-PAN3 deadenylation complex subunit PAN3", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" }, { "name": "PAN complex", "id": "GO:0031251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031251", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" }, { "name": "positive regulation of cytoplasmic mRNA processing body assembly", "id": "GO:0010606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010606", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0000289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000289", "evidence": [ { "database": "UniProtKB", "id": "E7EXP6", "url": "https://www.uniprot.org/uniprotkb/E7EXP6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7EXZ6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXZ6", "url": "https://www.uniprot.org/uniprotkb/E7EXZ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 65, "chemical_mass": 7427.0, "gene_names": "uqcc6;brawnin;br;bsi:ch211-68a17.7;gb:cn833218;si:ch211-68a17.7;uqcc6", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 6", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E7EXZ6", "url": "https://www.uniprot.org/uniprotkb/E7EXZ6" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "E7EXZ6", "url": "https://www.uniprot.org/uniprotkb/E7EXZ6" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "E7EXZ6", "url": "https://www.uniprot.org/uniprotkb/E7EXZ6" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "E7EXZ6", "url": "https://www.uniprot.org/uniprotkb/E7EXZ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7EY42-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EY42", "url": "https://www.uniprot.org/uniprotkb/E7EY42" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 452, "chemical_mass": 53229.0, "gene_names": "ptdss2;PSS-2;ptdss2;si:ch1073-158c2;si:ch1073-279O1", "protein_name": "Phosphatidylserine synthase 2", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E7EY42", "url": "https://www.uniprot.org/uniprotkb/E7EY42" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylserine biosynthetic process", "id": "GO:0006659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006659", "evidence": [ { "database": "UniProtKB", "id": "E7EY42", "url": "https://www.uniprot.org/uniprotkb/E7EY42" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-serine-phosphatidylethanolamine phosphatidyltransferase activity", "id": "GO:0106245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106245", "evidence": [ { "database": "UniProtKB", "id": "E7EY42", "url": "https://www.uniprot.org/uniprotkb/E7EY42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7EZI4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 430, "chemical_mass": 47723.0, "gene_names": "zdhhc11;dhhc11", "protein_name": "Palmitoyltransferase ZDHHC11", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "pmid": "" }, { "name": "peptidyl-L-cysteine S-palmitoylation", "id": "GO:0018230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018230", "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "E7EZI4", "url": "https://www.uniprot.org/uniprotkb/E7EZI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F022-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1351, "chemical_mass": 148174.0, "gene_names": "xdh;xdh", "protein_name": "Xanthine dehydrogenase/oxidase", "disease": [ { "disease_id": "DOID:0070452", "name": "xanthinuria type I", "description": "A xanthinuria characterized by isolated deficiency of xanthine dehydrogenase that has_material_basis_in homozygous or compound heterozygous mutation in the XDH gene on chromosome 2p23.", "url": "https://disease-ontology.org/term/DOID:0070452", "evidence": [ { "id": "0070452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070452" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1287", "name": "cardiovascular system disease", "description": "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.", "url": "https://disease-ontology.org/term/DOID:1287", "evidence": [ { "id": "1287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1287" } ], "weight": 0.0 }, { "disease_id": "DOID:1919", "name": "Lesch-Nyhan syndrome", "description": "A purine-pyrimidine metabolic disorder characterized by mental retardation, spastic cerebral palsy, choreoathetosis, uric acid urinary stones, and self-destructive biting of fingers and lips that has_material_basis_in mutation in the HPRT1 gene on chromosome Xq26.", "url": "https://disease-ontology.org/term/DOID:1919", "evidence": [ { "id": "1919", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1919" } ], "weight": 0.0 }, { "disease_id": "DOID:1920", "name": "hyperuricemia", "description": "An acquired metabolic disease that has_material_basis_in an abnormally high level of uric acid in the blood.", "url": "https://disease-ontology.org/term/DOID:1920", "evidence": [ { "id": "1920", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1920" } ], "weight": 0.0 }, { "disease_id": "DOID:2876", "name": "laryngeal squamous cell carcinoma", "description": "A laryngeal carcinoma that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:2876", "evidence": [ { "id": "2876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2876" } ], "weight": 0.0 }, { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 }, { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "molybdenum ion binding", "id": "GO:0030151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030151", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" }, { "name": "molybdopterin cofactor binding", "id": "GO:0043546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043546", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" }, { "name": "xanthine dehydrogenase activity", "id": "GO:0004854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004854", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" }, { "name": "xanthine oxidase activity", "id": "GO:0004855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004855", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" } ], "biological_process": [ { "name": "xanthine catabolic process", "id": "GO:0009115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009115", "evidence": [ { "database": "UniProtKB", "id": "E7F022", "url": "https://www.uniprot.org/uniprotkb/E7F022" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F0Z8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 495, "chemical_mass": 54411.0, "gene_names": "notum2;notum2;si:dkey-3d18.6", "protein_name": "Carboxylesterase notum2", "disease": [], "biological_process": [ { "name": "protein depalmitoleylation", "id": "GO:1990697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990697", "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "pmid": "" } ], "molecular_function": [ { "name": "palmitoleyl hydrolase activity", "id": "GO:1990699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990699", "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "pmid": "" }, { "name": "protein-containing complex destabilizing activity", "id": "GO:0140776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140776", "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E7F0Z8", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7F0Z8-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Asn397", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 397, "start_aa": "Asn", "end_pos": 397, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn397", "evidence": [ { "id": "E7F0Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Z8#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F211-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1198, "chemical_mass": 134999.0, "gene_names": "ttc17;ttc17", "protein_name": "Tetratricopeptide repeat protein 17", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "pmid": "" }, { "name": "determination of heart left/right asymmetry", "id": "GO:0061371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061371", "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "E7F211", "url": "https://www.uniprot.org/uniprotkb/E7F211" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F240-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F240", "url": "https://www.uniprot.org/uniprotkb/E7F240" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 595, "chemical_mass": 66359.0, "gene_names": "trappc14;c7h7orf43;gb:dn856615;map11;si:dkey-3k24.5;trappc14", "protein_name": "Trafficking protein particle complex subunit 14", "disease": [ { "disease_id": "DOID:0051036", "name": "primary autosomal recessive microcephaly 25", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous mutation in the MAP11 gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0051036", "evidence": [ { "id": "0051036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051036" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "E7F240", "url": "https://www.uniprot.org/uniprotkb/E7F240" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E7F240", "url": "https://www.uniprot.org/uniprotkb/E7F240" } ], "pmid": "" } ], "cellular_component": [ { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "E7F240", "url": "https://www.uniprot.org/uniprotkb/E7F240" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "E7F240", "url": "https://www.uniprot.org/uniprotkb/E7F240" } ], "pmid": "" }, { "name": "TRAPPII protein complex", "id": "GO:1990071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990071", "evidence": [ { "database": "UniProtKB", "id": "E7F240", "url": "https://www.uniprot.org/uniprotkb/E7F240" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "E7F240", "url": "https://www.uniprot.org/uniprotkb/E7F240" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7F240-1", "start_pos": "556", "end_pos": "556", "site_lbl": "Thr556", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 556, "start_aa": "Thr", "end_pos": 556, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr556", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F2J6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 667, "chemical_mass": 71895.0, "gene_names": "pcsk9;pcsk9", "protein_name": "Proprotein convertase subtilisin/kexin type 9", "disease": [ { "disease_id": "DOID:13810", "name": "familial hypercholesterolemia", "description": "A familial hyperlipidemia characterized by very high levels of low-density lipoprotein (LDL) and early cardiovascular disease.", "url": "https://disease-ontology.org/term/DOID:13810", "evidence": [ { "id": "13810", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13810" } ], "weight": 0.0 }, { "disease_id": "DOID:1390", "name": "hypobetalipoproteinemia", "description": "A hypolipoproteinemia characterized by permanently low levels of apolipoprotein B and LDL cholesterol resulting from an impaired ability to absorb and transport fats.", "url": "https://disease-ontology.org/term/DOID:1390", "evidence": [ { "id": "1390", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1390" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "regulation of neuron apoptotic process", "id": "GO:0043523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043523", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "E7F2J6", "url": "https://www.uniprot.org/uniprotkb/E7F2J6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F4J7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 4119, "chemical_mass": 467016.0, "gene_names": "prkdc;prkdc", "protein_name": "DNA-dependent protein kinase catalytic subunit", "disease": [ { "disease_id": "DOID:0090013", "name": "severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive", "description": "A severe combined immunodeficiency characterized by being T cell-negative, B cell-negative and natural killer cell-positive and that has_material_basis_in mutation in the RAG1 and RAG2 genes on chromosome 11p12.", "url": "https://disease-ontology.org/term/DOID:0090013", "evidence": [ { "id": "0090013", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090013" } ], "weight": 0.0 }, { "disease_id": "DOID:0111961", "name": "immunodeficiency 26", "description": "A severe combined immunodeficiency characterized by virtually absent peripheral B and T cells but normal numbers of NK cells, complete block in B-cell differentiation, and a defect in slow repair of DNA double-strand breaks in fibroblasts, that has_material_basis_in homozygous or compound heterozygous mutation in the PRKDC gene on chromosome 8q11.21.", "url": "https://disease-ontology.org/term/DOID:0111961", "evidence": [ { "id": "0111961", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111961" } ], "weight": 0.0 }, { "disease_id": "DOID:627", "name": "severe combined immunodeficiency", "description": "A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems.", "url": "https://disease-ontology.org/term/DOID:627", "evidence": [ { "id": "627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:627" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "DNA-dependent protein kinase activity", "id": "GO:0004677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004677", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" } ], "biological_process": [ { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "B cell differentiation", "id": "GO:0030183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030183", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "T cell receptor V(D)J recombination", "id": "GO:0033153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033153", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "immunoglobulin V(D)J recombination", "id": "GO:0033152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033152", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" }, { "name": "immunoglobulin heavy chain V-D-J recombination", "id": "GO:0071707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071707", "evidence": [ { "database": "UniProtKB", "id": "E7F4J7", "url": "https://www.uniprot.org/uniprotkb/E7F4J7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7F4J7-1", "start_pos": "1649", "end_pos": "1649", "site_lbl": "Thr1649", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1649, "start_aa": "Thr", "end_pos": 1649, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1649", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F4V8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 312, "chemical_mass": 35131.0, "gene_names": "pex2;pex2;pxmp3", "protein_name": "Peroxisome biogenesis factor 2", "disease": [ { "disease_id": "DOID:0080480", "name": "peroxisome biogenesis disorder 5A", "description": "A Zellweger syndrome that has_material_basis_in homozygous mutation in the PEX2 gene on chromosome 8q21.", "url": "https://disease-ontology.org/term/DOID:0080480", "evidence": [ { "id": "0080480", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080480" } ], "weight": 0.0 }, { "disease_id": "DOID:0081434", "name": "Peroxisome biogenesis disorder 5B", "description": "A peroxisomal biogenesis disorder that is characterized by the overlapping phenotypes of neonatal adrenoleukodystrophy and infantile Refsum disease and that has_material_basis_in homozygous or compound heterozygous mutation in the PEX2 gene on chromosome 8q21.", "url": "https://disease-ontology.org/term/DOID:0081434", "evidence": [ { "id": "0081434", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081434" } ], "weight": 0.0 }, { "disease_id": "DOID:905", "name": "Zellweger syndrome", "description": "A peroxisomal biogenesis disorder that is characterized by severe neurologic dysfunction, craniofacial abnormalities, and liver dysfunction, and biochemically by the absence of peroxisome and that has_material_basis_in autosomal recessive inheritance of a mutation in the peroxisome biogenesis factor (PEX) genes.", "url": "https://disease-ontology.org/term/DOID:905", "evidence": [ { "id": "905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:905" } ], "weight": 0.0 }, { "disease_id": "DOID:906", "name": "peroxisomal disease", "description": "An inherited metabolic disorder that involves peroxisome malfunction.", "url": "https://disease-ontology.org/term/DOID:906", "evidence": [ { "id": "906", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:906" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" } ], "biological_process": [ { "name": "peroxisome organization", "id": "GO:0007031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007031", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" }, { "name": "response to amino acid starvation", "id": "GO:1990928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990928", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix, receptor recycling", "id": "GO:0016562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016562", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix", "id": "GO:0016558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016558", "evidence": [ { "database": "UniProtKB", "id": "E7F4V8", "url": "https://www.uniprot.org/uniprotkb/E7F4V8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F587-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 323, "chemical_mass": 37305.0, "gene_names": "zdhhc20b;si:dkey-11p10.6;zdhhc20", "protein_name": "Palmitoyltransferase ZDHHC20-B", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "protein-cysteine S-myristoyltransferase activity", "id": "GO:0019705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019705", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "protein-cysteine S-stearoyltransferase activity", "id": "GO:0140439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140439", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "protein palmitoylation", "id": "GO:0018345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018345", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" }, { "name": "synaptic vesicle maturation", "id": "GO:0016188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016188", "evidence": [ { "database": "UniProtKB", "id": "E7F587", "url": "https://www.uniprot.org/uniprotkb/E7F587" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F5E1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F5E1", "url": "https://www.uniprot.org/uniprotkb/E7F5E1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1367, "chemical_mass": 155016.0, "gene_names": "cep162;cep162;si:ch211-198c19.2", "protein_name": "Centrosomal protein of 162 kDa", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E7F5E1", "url": "https://www.uniprot.org/uniprotkb/E7F5E1" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E7F5E1", "url": "https://www.uniprot.org/uniprotkb/E7F5E1" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "E7F5E1", "url": "https://www.uniprot.org/uniprotkb/E7F5E1" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "E7F5E1", "url": "https://www.uniprot.org/uniprotkb/E7F5E1" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E7F5E1", "url": "https://www.uniprot.org/uniprotkb/E7F5E1" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E7F5E1", "url": "https://www.uniprot.org/uniprotkb/E7F5E1" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "E7F5E1", "url": "https://www.uniprot.org/uniprotkb/E7F5E1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F5F0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F5F0", "url": "https://www.uniprot.org/uniprotkb/E7F5F0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 169, "chemical_mass": 19152.0, "gene_names": "alkal2a", "protein_name": "ALK and LTK ligand 2a", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7F5F0", "url": "https://www.uniprot.org/uniprotkb/E7F5F0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F5F0", "url": "https://www.uniprot.org/uniprotkb/E7F5F0" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "E7F5F0", "url": "https://www.uniprot.org/uniprotkb/E7F5F0" } ], "pmid": "" }, { "name": "positive regulation of ERK5 cascade", "id": "GO:0070378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070378", "evidence": [ { "database": "UniProtKB", "id": "E7F5F0", "url": "https://www.uniprot.org/uniprotkb/E7F5F0" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "E7F5F0", "url": "https://www.uniprot.org/uniprotkb/E7F5F0" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "E7F5F0", "url": "https://www.uniprot.org/uniprotkb/E7F5F0" } ], "pmid": "" }, { "name": "receptor signaling protein tyrosine kinase activator activity", "id": "GO:0030298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030298", "evidence": [ { "database": "UniProtKB", "id": "E7F5F0", "url": "https://www.uniprot.org/uniprotkb/E7F5F0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F6D7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F6D7", "url": "https://www.uniprot.org/uniprotkb/E7F6D7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 412, "chemical_mass": 47805.0, "gene_names": "zdhhc6;dhhc6;fa04d12;fc30b09;wu:fa04d12;wu:fc30b09;zdhhc6", "protein_name": "Palmitoyltransferase ZDHHC6", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E7F6D7", "url": "https://www.uniprot.org/uniprotkb/E7F6D7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E7F6D7", "url": "https://www.uniprot.org/uniprotkb/E7F6D7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E7F6D7", "url": "https://www.uniprot.org/uniprotkb/E7F6D7" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "E7F6D7", "url": "https://www.uniprot.org/uniprotkb/E7F6D7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "E7F6D7", "url": "https://www.uniprot.org/uniprotkb/E7F6D7" } ], "pmid": "" }, { "name": "protein-cysteine S-stearoyltransferase activity", "id": "GO:0140439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140439", "evidence": [ { "database": "UniProtKB", "id": "E7F6D7", "url": "https://www.uniprot.org/uniprotkb/E7F6D7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F6M7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F6M7", "url": "https://www.uniprot.org/uniprotkb/E7F6M7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 826, "chemical_mass": 93379.0, "gene_names": "gpam;gpam", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "disease": [], "biological_process": [ { "name": "glycerophospholipid metabolic process", "id": "GO:0006650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006650", "evidence": [ { "database": "UniProtKB", "id": "E7F6M7", "url": "https://www.uniprot.org/uniprotkb/E7F6M7" } ], "pmid": "" }, { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "E7F6M7", "url": "https://www.uniprot.org/uniprotkb/E7F6M7" } ], "pmid": "" }, { "name": "CDP-diacylglycerol biosynthetic process", "id": "GO:0016024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016024", "evidence": [ { "database": "UniProtKB", "id": "E7F6M7", "url": "https://www.uniprot.org/uniprotkb/E7F6M7" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E7F6M7", "url": "https://www.uniprot.org/uniprotkb/E7F6M7" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E7F6M7", "url": "https://www.uniprot.org/uniprotkb/E7F6M7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F6M7", "url": "https://www.uniprot.org/uniprotkb/E7F6M7" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycerol-3-phosphate O-acyltransferase activity", "id": "GO:0004366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004366", "evidence": [ { "database": "UniProtKB", "id": "E7F6M7", "url": "https://www.uniprot.org/uniprotkb/E7F6M7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F6T0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 392, "chemical_mass": 43190.0, "gene_names": "cd44a;cd44a", "protein_name": "CD44 antigen", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:3007", "name": "breast ductal carcinoma", "description": "A breast carcinoma that derives_from the lining of milk ducts.", "url": "https://disease-ontology.org/term/DOID:3007", "evidence": [ { "id": "3007", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3007" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3457", "name": "invasive lobular carcinoma", "description": "A breast lobular carcinoma that is characterized by infiltration into the tissue of the breast outside of the lobule where it originated.", "url": "https://disease-ontology.org/term/DOID:3457", "evidence": [ { "id": "3457", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3457" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:5138", "name": "leiomyomatosis", "description": "A leiomyoma that is multiple and diffuse.", "url": "https://disease-ontology.org/term/DOID:5138", "evidence": [ { "id": "5138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5138" } ], "weight": 0.0 }, { "disease_id": "DOID:9597", "name": "Krukenberg carcinoma", "description": "An ovary epithelial cancer that is a metastatic signet-ring cell carcinoma, which spreads to the ovary from gastric tissue.", "url": "https://disease-ontology.org/term/DOID:9597", "evidence": [ { "id": "9597", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9597" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "macrophage migration inhibitory factor receptor complex", "id": "GO:0035692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035692", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" } ], "biological_process": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "E7F6T0", "url": "https://www.uniprot.org/uniprotkb/E7F6T0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F6T8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 937, "chemical_mass": 105264.0, "gene_names": "usp37;fi15b04;usp37;wu:fi15b04;wu:fi38d03;zgc:152882;zgc:153999", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37", "disease": [], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "central nervous system morphogenesis", "id": "GO:0021551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021551", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E7F6T8", "url": "https://www.uniprot.org/uniprotkb/E7F6T8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F8F4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1534, "chemical_mass": 175219.0, "gene_names": "ascc3", "protein_name": "Activating signal cointegrator 1 complex subunit 3", "disease": [ { "disease_id": "DOID:0060308", "name": "autosomal recessive intellectual developmental disorder", "description": "A intellectual disability characterized by an autosomal recessive inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060308", "evidence": [ { "id": "0060308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060308" } ], "weight": 0.0 } ], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "DNA alkylation repair", "id": "GO:0006307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006307", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" } ], "molecular_function": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E7F8F4", "url": "https://www.uniprot.org/uniprotkb/E7F8F4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F9C4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 553, "chemical_mass": 62420.0, "gene_names": "prkaa2;prkaa2", "protein_name": "5'-AMP-activated protein kinase catalytic subunit alpha-2", "disease": [ { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "AMP-activated protein kinase activity", "id": "GO:0004679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004679", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity", "id": "GO:0047322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047322", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "nucleotide-activated protein kinase complex", "id": "GO:0031588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031588", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" }, { "name": "protein localization to lipid droplet", "id": "GO:1990044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990044", "evidence": [ { "database": "UniProtKB", "id": "E7F9C4", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F9T0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1214, "chemical_mass": 138021.0, "gene_names": "mical1;MICAL-1;mical1;zgc:171928", "protein_name": "[F-actin]-monooxygenase mical1", "disease": [], "molecular_function": [ { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen", "id": "GO:0016709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016709", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "NAD(P)H oxidase H2O2-forming activity", "id": "GO:0016174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016174", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "F-actin monooxygenase activity", "id": "GO:0120501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120501", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "sulfur oxidation", "id": "GO:0019417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019417", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" }, { "name": "actin filament depolymerization", "id": "GO:0030042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030042", "evidence": [ { "database": "UniProtKB", "id": "E7F9T0", "url": "https://www.uniprot.org/uniprotkb/E7F9T0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7F9V1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 540, "chemical_mass": 62145.0, "gene_names": "chrng;chrngl;chrng;wu:fc54e06", "protein_name": "", "disease": [ { "disease_id": "DOID:0080110", "name": "contractures, pterygia, and spondylocarpotarsal fusion syndrome", "description": "A syndrome that is characterized by permanently bent fingers, short stature, rocker-bottom or club feet, joints that are bent in a fixed position, union or webbing of the skin between the fingers, and/or webbing of the neck, inside bend of the elbows, back of the knees and armpits.", "url": "https://disease-ontology.org/term/DOID:0080110", "evidence": [ { "id": "0080110", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080110" } ], "weight": 0.0 } ], "biological_process": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "synaptic transmission, cholinergic", "id": "GO:0007271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007271", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "acetylcholine receptor signaling pathway", "id": "GO:0095500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0095500", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "membrane depolarization", "id": "GO:0051899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051899", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "cellular response to acetylcholine", "id": "GO:1905145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905145", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "acetylcholine-gated monoatomic cation-selective channel activity", "id": "GO:0022848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022848", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "acetylcholine-gated channel complex", "id": "GO:0005892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005892", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "E7F9V1", "url": "https://www.uniprot.org/uniprotkb/E7F9V1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FAI5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 632, "chemical_mass": 70568.0, "gene_names": "ryk;ryk;wu:fb37b12;wu:fi05b06;zgc:158381", "protein_name": "Tyrosine-protein kinase RYK", "disease": [], "molecular_function": [ { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "cell migration involved in gastrulation", "id": "GO:0042074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042074", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "Wnt signaling pathway, planar cell polarity pathway", "id": "GO:0060071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060071", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "Wnt signaling pathway, calcium modulating pathway", "id": "GO:0007223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007223", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "convergent extension involved in axis elongation", "id": "GO:0060028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060028", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "convergent extension", "id": "GO:0060026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060026", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" }, { "name": "dorsal convergence", "id": "GO:0060030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060030", "evidence": [ { "database": "UniProtKB", "id": "E7FAI5", "url": "https://www.uniprot.org/uniprotkb/E7FAI5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FAP1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 630, "chemical_mass": 71358.0, "gene_names": "rnf169;fc92e10;rnf169;wu:fc92e10", "protein_name": "E3 ubiquitin-protein ligase RNF169", "disease": [], "biological_process": [ { "name": "negative regulation of double-strand break repair", "id": "GO:2000780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000780", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "E7FAP1", "url": "https://www.uniprot.org/uniprotkb/E7FAP1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FAP8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 195, "chemical_mass": 22508.0, "gene_names": "alkal2b;aug-a2;aug-alpha2;fam150bb", "protein_name": "ALK and LTK ligand 2b", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "pmid": "" }, { "name": "positive regulation of ERK5 cascade", "id": "GO:0070378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070378", "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "pmid": "" }, { "name": "iridophore differentiation", "id": "GO:0050935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050935", "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "pmid": "" }, { "name": "receptor signaling protein tyrosine kinase activator activity", "id": "GO:0030298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030298", "evidence": [ { "database": "UniProtKB", "id": "E7FAP8", "url": "https://www.uniprot.org/uniprotkb/E7FAP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FBW8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 353, "chemical_mass": 40226.0, "gene_names": "hapln1b;hapln1b", "protein_name": "Hyaluronan and proteoglycan link protein 1", "disease": [ { "disease_id": "DOID:14789", "name": "spondyloepiphyseal dysplasia congenita", "description": "A spondyloepiphyseal dysplasia characterized by disproportionate short stature (short trunk), abnormal epiphyses, and flattened vertebral bodies that has_material_basis_in heterozygous mutation in the COL2A1 gene on chromosome 12q13.11.", "url": "https://disease-ontology.org/term/DOID:14789", "evidence": [ { "id": "14789", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14789" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cardiac muscle tissue regeneration", "id": "GO:0061026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061026", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" }, { "name": "perineuronal net", "id": "GO:0072534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072534", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" } ], "molecular_function": [ { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "E7FBW8", "url": "https://www.uniprot.org/uniprotkb/E7FBW8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FCU0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 279, "chemical_mass": 31159.0, "gene_names": "npm1a;npm1a;npm1;sb:cb487", "protein_name": "Nucleophosmin", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of centrosome duplication", "id": "GO:0010824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010824", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "E7FCU0", "url": "https://www.uniprot.org/uniprotkb/E7FCU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FD27-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 425, "chemical_mass": 47238.0, "gene_names": "kcnj10a;kcnj10a", "protein_name": "", "disease": [ { "disease_id": "DOID:0060484", "name": "EAST syndrome", "description": "A syndrome characterized by seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance and has_material_basis_in homozygous or compound heterozygous mutation in the KCNJ10 gene on chromosome 1q23.", "url": "https://disease-ontology.org/term/DOID:0060484", "evidence": [ { "id": "0060484", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060484" } ], "weight": 0.0 }, { "disease_id": "DOID:0110498", "name": "autosomal recessive nonsyndromic deafness 4", "description": "An autosomal recessive nonsyndromic deafness that has_material_basis_in mutation in the SLC26A4 gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0110498", "evidence": [ { "id": "0110498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110498" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" }, { "name": "regulation of monoatomic ion transmembrane transport", "id": "GO:0034765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034765", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" }, { "name": "locomotion", "id": "GO:0040011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040011", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" }, { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" }, { "name": "swimming", "id": "GO:0036268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036268", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" }, { "name": "larval locomotory behavior", "id": "GO:0008345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008345", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" } ], "molecular_function": [ { "name": "inward rectifier potassium channel activity", "id": "GO:0005242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005242", "evidence": [ { "database": "UniProtKB", "id": "E7FD27", "url": "https://www.uniprot.org/uniprotkb/E7FD27" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7FD27-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Thr319", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 319, "start_aa": "Thr", "end_pos": 319, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr319", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FDV5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FDV5", "url": "https://www.uniprot.org/uniprotkb/E7FDV5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 295, "chemical_mass": 33685.0, "gene_names": "iyd;iyd;si:ch211-286f9.2;si:dkey-3p8.3", "protein_name": "Iodotyrosine deiodinase", "disease": [ { "disease_id": "DOID:0112188", "name": "thyroid dyshormonogenesis 4", "description": "A familial thyroid dyshormonogenesis that has_material_basis_in homozygous or compound heterozygous mutation in IYD on chromosome 6q25.1.", "url": "https://disease-ontology.org/term/DOID:0112188", "evidence": [ { "id": "0112188", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112188" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7FDV5", "url": "https://www.uniprot.org/uniprotkb/E7FDV5" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "E7FDV5", "url": "https://www.uniprot.org/uniprotkb/E7FDV5" } ], "pmid": "" }, { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "E7FDV5", "url": "https://www.uniprot.org/uniprotkb/E7FDV5" } ], "pmid": "" }, { "name": "iodotyrosine deiodinase activity", "id": "GO:0140616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140616", "evidence": [ { "database": "UniProtKB", "id": "E7FDV5", "url": "https://www.uniprot.org/uniprotkb/E7FDV5" } ], "pmid": "" } ], "biological_process": [ { "name": "tyrosine metabolic process", "id": "GO:0006570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006570", "evidence": [ { "database": "UniProtKB", "id": "E7FDV5", "url": "https://www.uniprot.org/uniprotkb/E7FDV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FE40-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FE40", "url": "https://www.uniprot.org/uniprotkb/E7FE40" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 446, "chemical_mass": 51780.0, "gene_names": "nemp1;nemp1;si:dkey-126g1.8;tmem194a", "protein_name": "Nuclear envelope integral membrane protein 1", "disease": [], "biological_process": [ { "name": "erythrocyte maturation", "id": "GO:0043249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043249", "evidence": [ { "database": "UniProtKB", "id": "E7FE40", "url": "https://www.uniprot.org/uniprotkb/E7FE40" } ], "pmid": "" }, { "name": "oocyte maturation", "id": "GO:0001556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001556", "evidence": [ { "database": "UniProtKB", "id": "E7FE40", "url": "https://www.uniprot.org/uniprotkb/E7FE40" } ], "pmid": "" }, { "name": "erythrocyte enucleation", "id": "GO:0043131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043131", "evidence": [ { "database": "UniProtKB", "id": "E7FE40", "url": "https://www.uniprot.org/uniprotkb/E7FE40" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "E7FE40", "url": "https://www.uniprot.org/uniprotkb/E7FE40" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "E7FE40", "url": "https://www.uniprot.org/uniprotkb/E7FE40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7FE40-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Asn118", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 118, "start_aa": "Asn", "end_pos": 118, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "E7FE40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE40#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E7FE40-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Asn129", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 129, "start_aa": "Asn", "end_pos": 129, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn129", "evidence": [ { "id": "E7FE40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE40#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E7FE40-1", "start_pos": "441", "end_pos": "441", "site_lbl": "Asn441", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 441, "start_aa": "Asn", "end_pos": 441, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn441", "evidence": [ { "id": "E7FE40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE40#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E7FE40-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Asn62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 62, "start_aa": "Asn", "end_pos": 62, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "E7FE40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE40#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FEV0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2065, "chemical_mass": 228484.0, "gene_names": "wdr81;fc37g06;wdr81;wu:fc37g06", "protein_name": "WD repeat-containing protein 81", "disease": [ { "disease_id": "DOID:0070557", "name": "cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 2", "description": "A cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome that has_material_basis_in homozygous mutation in the WDR81 gene on chromosome 17p13.3.", "url": "https://disease-ontology.org/term/DOID:0070557", "evidence": [ { "id": "0070557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070557" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" } ], "biological_process": [ { "name": "early endosome to late endosome transport", "id": "GO:0045022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "aggrephagy", "id": "GO:0035973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035973", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol 3-kinase regulator activity", "id": "GO:0035014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035014", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase inhibitor activity", "id": "GO:0141039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141039", "evidence": [ { "database": "UniProtKB", "id": "E7FEV0", "url": "https://www.uniprot.org/uniprotkb/E7FEV0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7FEV0-1", "start_pos": "1717", "end_pos": "1717", "site_lbl": "Thr1717", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1717, "start_aa": "Thr", "end_pos": 1717, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1717", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FFX1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 844, "chemical_mass": 93724.0, "gene_names": "npas4b;si:dkey-17e16.11", "protein_name": "Neuronal PAS domain-containing protein 4B", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "learning", "id": "GO:0007612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007612", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "excitatory postsynaptic potential", "id": "GO:0060079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060079", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "short-term memory", "id": "GO:0007614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007614", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "inhibitory postsynaptic potential", "id": "GO:0060080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060080", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, GABAergic", "id": "GO:0032228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032228", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "inhibitory synapse assembly", "id": "GO:1904862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904862", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E7FFX1", "url": "https://www.uniprot.org/uniprotkb/E7FFX1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E7FFX1-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Thr275", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 275, "start_aa": "Thr", "end_pos": 275, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr275", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FGQ8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 251, "chemical_mass": 28180.0, "gene_names": "gch1;gch1a;gch1;wu:fc16b10;zgc:195269", "protein_name": "GTP cyclohydrolase 1", "disease": [ { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:0090043", "name": "dopa-responsive dystonia", "description": "A dystonia characterized by generalized dystonia, diurnal fluctuation of symptoms, and a dramatic therapeutic response to L-dopa that has_material_basis_in heterozygous mutation in the GCH1 gene on chromosome 14q13.", "url": "https://disease-ontology.org/term/DOID:0090043", "evidence": [ { "id": "0090043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090043" } ], "weight": 0.0 }, { "disease_id": "DOID:0112225", "name": "BH4-deficient hyperphenylalaninemia B", "description": "A tetrahydrobiopterin (BH4)-deficient hyperphenylalaninemia that is characterized by hyperphenylalaninemia, depletion of the neurotransmitters dopamine and serotonin, and progressive cognitive and motor deficits that has_material_basis_in homozygous or compound heterozygous mutation in the GCH1 gene on chromosome 14q22.2.", "url": "https://disease-ontology.org/term/DOID:0112225", "evidence": [ { "id": "0112225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112225" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain.", "url": "https://disease-ontology.org/term/DOID:10923", "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ], "weight": 0.0 }, { "disease_id": "DOID:11713", "name": "diabetic angiopathy", "description": "A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.", "url": "https://disease-ontology.org/term/DOID:11713", "evidence": [ { "id": "11713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11713" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:543", "name": "dystonia", "description": "A movement disease that is characterized by involuntary muscle contractions causing repetitive or twisting movements.", "url": "https://disease-ontology.org/term/DOID:543", "evidence": [ { "id": "543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:543" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "tetrahydrofolate biosynthetic process", "id": "GO:0046654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046654", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" }, { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" }, { "name": "tetrahydrobiopterin biosynthetic process", "id": "GO:0006729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006729", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" }, { "name": "regulation of innate immune response", "id": "GO:0045088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045088", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" }, { "name": "GTP cyclohydrolase I activity", "id": "GO:0003934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003934", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ8", "url": "https://www.uniprot.org/uniprotkb/E7FGQ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E7FGY2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 229, "chemical_mass": 26873.0, "gene_names": "gid8b;Twa1;c20orf11;cb482;gid8b;twa1", "protein_name": "Glucose-induced degradation protein 8-B homolog", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "pmid": "" }, { "name": "determination of dorsal identity", "id": "GO:0048263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048263", "evidence": [ { "database": "UniProtKB", "id": "E7FGY2", "url": "https://www.uniprot.org/uniprotkb/E7FGY2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QB71-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 701, "chemical_mass": 80155.0, "gene_names": "kif3a;fc55h04;kif3a;wu:fc55h04;zgc:110284", "protein_name": "Kinesin-like protein", "disease": [ { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:10325", "name": "silicosis", "description": "A pneumoconiosis that is an inflammation and scarring of the upper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles.", "url": "https://disease-ontology.org/term/DOID:10325", "evidence": [ { "id": "10325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10325" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:1934", "name": "dysostosis", "description": "A bone development disease that results in defective ossification of bone.", "url": "https://disease-ontology.org/term/DOID:1934", "evidence": [ { "id": "1934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1934" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "kinesin II complex", "id": "GO:0016939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016939", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" } ], "biological_process": [ { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "anterograde axonal transport", "id": "GO:0008089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008089", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "photoreceptor cell outer segment organization", "id": "GO:0035845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035845", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "E9QB71", "url": "https://www.uniprot.org/uniprotkb/E9QB71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QCG4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 245, "chemical_mass": 26559.0, "gene_names": "rbm24b;rbm24b;zgc:136803", "protein_name": "", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of myotube differentiation", "id": "GO:0010831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010831", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "circulatory system development", "id": "GO:0072359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072359", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "somitogenesis", "id": "GO:0001756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001756", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "embryonic neurocranium morphogenesis", "id": "GO:0048702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048702", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "ventricular cardiac muscle tissue development", "id": "GO:0003229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003229", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "atrial cardiac muscle tissue development", "id": "GO:0003228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003228", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "E9QCG4", "url": "https://www.uniprot.org/uniprotkb/E9QCG4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QCX4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 179, "chemical_mass": 20158.0, "gene_names": "tcap;tcap", "protein_name": "", "disease": [ { "disease_id": "DOID:0110281", "name": "autosomal recessive limb-girdle muscular dystrophy type 2G", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in mutation in the gene encoding telethonin (TCAP).", "url": "https://disease-ontology.org/term/DOID:0110281", "evidence": [ { "id": "0110281", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110281" } ], "weight": 0.0 }, { "disease_id": "DOID:0110328", "name": "hypertrophic cardiomyopathy 25", "description": "A familial hypertrophic cardiomyopathy that has_material_basis_in heterozygous mutation in the TCAP gene on chromosome 17q12.", "url": "https://disease-ontology.org/term/DOID:0110328", "evidence": [ { "id": "0110328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110328" } ], "weight": 0.0 } ], "biological_process": [ { "name": "detection of muscle stretch", "id": "GO:0035995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035995", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "skeletal muscle thin filament assembly", "id": "GO:0030240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030240", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "skeletal muscle fiber development", "id": "GO:0048741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048741", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "cardiac myofibril assembly", "id": "GO:0055003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055003", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "cardiac muscle tissue morphogenesis", "id": "GO:0055008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055008", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "cardiac muscle contraction", "id": "GO:0060048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060048", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "regulation of reactive oxygen species metabolic process", "id": "GO:2000377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000377", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "T-tubule organization", "id": "GO:0033292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033292", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "muscle cell development", "id": "GO:0055001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055001", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "skeletal muscle myosin thick filament assembly", "id": "GO:0030241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030241", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "sarcomerogenesis", "id": "GO:0048769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048769", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "cellular respiration", "id": "GO:0045333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045333", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" }, { "name": "titin binding", "id": "GO:0031432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031432", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" } ], "cellular_component": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "E9QCX4", "url": "https://www.uniprot.org/uniprotkb/E9QCX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QDP8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 372, "chemical_mass": 42615.0, "gene_names": "il7r;il-7ra;il7r", "protein_name": "", "disease": [ { "disease_id": "DOID:0090014", "name": "severe combined immunodeficiency 104", "description": "A severe combined immunodeficiency that is characterized by the onset of recurrent infections in early infancy and that has_material_basis_in homozygous or compound heterozygous mutation in the interleukin-7 receptor gene (IL7R) on chromosome 5p13.", "url": "https://disease-ontology.org/term/DOID:0090014", "evidence": [ { "id": "0090014", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090014" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:627", "name": "severe combined immunodeficiency", "description": "A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems.", "url": "https://disease-ontology.org/term/DOID:627", "evidence": [ { "id": "627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:627" } ], "weight": 0.0 }, { "disease_id": "DOID:7474", "name": "malignant pleural mesothelioma", "description": "A pleural cancer that has_material_basis_in mesothelium cells.", "url": "https://disease-ontology.org/term/DOID:7474", "evidence": [ { "id": "7474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7474" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "interleukin-7 receptor activity", "id": "GO:0004917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004917", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" } ], "biological_process": [ { "name": "neural retina development", "id": "GO:0003407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003407", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "central nervous system myelination", "id": "GO:0022010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022010", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "myelination in peripheral nervous system", "id": "GO:0022011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022011", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "positive regulation of receptor signaling pathway via JAK-STAT", "id": "GO:0046427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046427", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "interleukin-7-mediated signaling pathway", "id": "GO:0038111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038111", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "T cell differentiation in thymus", "id": "GO:0033077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033077", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "visual behavior", "id": "GO:0007632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007632", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E9QDP8", "url": "https://www.uniprot.org/uniprotkb/E9QDP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QEQ1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 100, "chemical_mass": 11163.0, "gene_names": "apoc2;apoc2;fb71a04;fb98g08;wu:fb52e03;wu:fb71a04;wu:fb98g08", "protein_name": "Apolipoprotein C-II", "disease": [ { "disease_id": "DOID:0111418", "name": "familial apolipoprotein C-II deficiency", "description": "A familial chylomicronemia syndrome characterized by onset in adolescence or adulthood of hypertriglyceridemia and fasting chylomicronemia that has_material_basis_in homozygous or compound heterozygous mutation in the APOC2 gene on chromosome 19q13.32.", "url": "https://disease-ontology.org/term/DOID:0111418", "evidence": [ { "id": "0111418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111418" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:1172", "name": "hyperlipoproteinemia type IV", "description": "", "url": "https://disease-ontology.org/term/DOID:1172", "evidence": [ { "id": "1172", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1172" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:1390", "name": "hypobetalipoproteinemia", "description": "A hypolipoproteinemia characterized by permanently low levels of apolipoprotein B and LDL cholesterol resulting from an impaired ability to absorb and transport fats.", "url": "https://disease-ontology.org/term/DOID:1390", "evidence": [ { "id": "1390", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1390" } ], "weight": 0.0 }, { "disease_id": "DOID:14118", "name": "familial lipoprotein lipase deficiency", "description": "A familial hyperlipemia characterized by a deficiency of the enzyme lipoprotein lipase and the subsequent build up of chylomicrons and increased plasma concentration of triglycerides.", "url": "https://disease-ontology.org/term/DOID:14118", "evidence": [ { "id": "14118", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14118" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "lipoprotein transport", "id": "GO:0042953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042953", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "high-density lipoprotein particle clearance", "id": "GO:0034384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034384", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "chylomicron remnant clearance", "id": "GO:0034382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034382", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "lipoprotein catabolic process", "id": "GO:0042159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042159", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "intermediate-density lipoprotein particle", "id": "GO:0034363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034363", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "very-low-density lipoprotein particle", "id": "GO:0034361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034361", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "spherical high-density lipoprotein particle", "id": "GO:0034366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034366", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "chylomicron", "id": "GO:0042627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042627", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "low-density lipoprotein particle", "id": "GO:0034362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034362", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipase activator activity", "id": "GO:0016004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016004", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" }, { "name": "phospholipase binding", "id": "GO:0043274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043274", "evidence": [ { "database": "UniProtKB", "id": "E9QEQ1", "url": "https://www.uniprot.org/uniprotkb/E9QEQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QG29-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 336, "chemical_mass": 38256.0, "gene_names": "tor1;im:7165310;si:ch73-178d14.1;tor1", "protein_name": "Torsin", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "pmid": "" } ], "biological_process": [ { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "pmid": "" }, { "name": "nuclear membrane organization", "id": "GO:0071763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071763", "evidence": [ { "database": "UniProtKB", "id": "E9QG29", "url": "https://www.uniprot.org/uniprotkb/E9QG29" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QH31-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 490, "chemical_mass": 55060.0, "gene_names": "aldh3a2b;aldh3a2b;zgc:103715", "protein_name": "Aldehyde dehydrogenase", "disease": [ { "disease_id": "DOID:14501", "name": "Sjogren-Larsson syndrome", "description": "A syndrome that is characterized by ichthyosis, mental retardation, spastic paraparesis, macular dystrophy, and leukoencephalopathy, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the aldehyde dehydrogenase 3 family member A2 (ALDH3A2) gene, which encodes fatty aldehyde dehydrogenase, on chromosome 17p11.", "url": "https://disease-ontology.org/term/DOID:14501", "evidence": [ { "id": "14501", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14501" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "pmid": "" }, { "name": "aldehyde metabolic process", "id": "GO:0006081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006081", "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-chloroallyl aldehyde dehydrogenase activity", "id": "GO:0004028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004028", "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "pmid": "" }, { "name": "aldehyde dehydrogenase (NAD+) activity", "id": "GO:0004029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004029", "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "pmid": "" }, { "name": "farnesal dehydrogenase (NAD+) activity", "id": "GO:0120553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120553", "evidence": [ { "database": "UniProtKB", "id": "E9QH31", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9QH31-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Thr121", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 121, "start_aa": "Thr", "end_pos": 121, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr121", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QHE3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 634, "chemical_mass": 72647.0, "gene_names": "rnf207b;rnf207b;rnf207", "protein_name": "RING finger protein 207", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" } ], "cellular_component": [ { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cardiac muscle contraction", "id": "GO:0055117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055117", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" }, { "name": "regulation of heart looping", "id": "GO:1901207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901207", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" }, { "name": "positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential", "id": "GO:1905026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905026", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" }, { "name": "positive regulation of membrane repolarization during cardiac muscle cell action potential", "id": "GO:1905033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905033", "evidence": [ { "database": "UniProtKB", "id": "E9QHE3", "url": "https://www.uniprot.org/uniprotkb/E9QHE3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QYE2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1811, "chemical_mass": 197465.0, "gene_names": "tncb;tenc;tncb;tnc;wu:fk04d02", "protein_name": "", "disease": [ { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0110581", "name": "autosomal dominant nonsyndromic deafness 56", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in mutation in the TNC gene on chromosome 9q33.", "url": "https://disease-ontology.org/term/DOID:0110581", "evidence": [ { "id": "0110581", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110581" } ], "weight": 0.0 }, { "disease_id": "DOID:10320", "name": "asbestosis", "description": "A pneumoconiosis caused by inhalation and retention of asbestos fibers.", "url": "https://disease-ontology.org/term/DOID:10320", "evidence": [ { "id": "10320", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10320" } ], "weight": 0.0 }, { "disease_id": "DOID:106", "name": "pleural tuberculosis", "description": "An extrapulmonary tuberculosis that results_in lymphocyte-predominant exudative pleural effusion, located_in pleura. This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac.", "url": "https://disease-ontology.org/term/DOID:106", "evidence": [ { "id": "106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:106" } ], "weight": 0.0 }, { "disease_id": "DOID:11204", "name": "allergic conjunctivitis", "description": "A chronic conjunctivitis that is an inflammation of the conjunctiva involing red, itchy, and watery eyes a resulting from an exposure to an allergen or an irritant.", "url": "https://disease-ontology.org/term/DOID:11204", "evidence": [ { "id": "11204", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11204" } ], "weight": 0.0 }, { "disease_id": "DOID:13100", "name": "intracranial vasospasm", "description": "", "url": "https://disease-ontology.org/term/DOID:13100", "evidence": [ { "id": "13100", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13100" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3798", "name": "pleural empyema", "description": "A soft tissue infectious disease that involves accumulation of pus in the pleural cavity as a result of infection within the lung (pneumonia) or a lung abscess spreading into the space. The symptoms include cough, fever, chest pain, sweating and shortness of breath.", "url": "https://disease-ontology.org/term/DOID:3798", "evidence": [ { "id": "3798", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3798" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.", "url": "https://disease-ontology.org/term/DOID:552", "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:841", "name": "extrinsic allergic alveolitis", "description": "An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. Symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.", "url": "https://disease-ontology.org/term/DOID:841", "evidence": [ { "id": "841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:841" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of axon regeneration", "id": "GO:0048680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048680", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "axonal fasciculation", "id": "GO:0007413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007413", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "positive regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045887", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "optic nerve development", "id": "GO:0021554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021554", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "negative regulation of axon extension", "id": "GO:0030517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030517", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "axon regeneration at neuromuscular junction", "id": "GO:0014814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014814", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1QYE2", "url": "https://www.uniprot.org/uniprotkb/F1QYE2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QIN8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 599, "chemical_mass": 67942.0, "gene_names": "klhl41a;kbtbd10a;klhl41a;si:dkey-211m23.4", "protein_name": "Kelch-like protein 41a", "disease": [ { "disease_id": "DOID:0110929", "name": "nemaline myopathy 9", "description": "A nemaline myopathy characterized by onset in early infancy of muscle weakness with variable severity that has_material_basis_in homozygous or compound heterozygous mutation in the KLHL41 gene on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0110929", "evidence": [ { "id": "0110929", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110929" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:3191", "name": "nemaline myopathy", "description": "A congenital myopathy characterized by generally non-progressive muscle weakness of varying severity and problems with the tone and contraction of skeletal muscles. The muscle cells contain abnormal clumps of threadlike material called nemaline bodies.", "url": "https://disease-ontology.org/term/DOID:3191", "evidence": [ { "id": "3191", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3191" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" }, { "name": "skeletal muscle fiber development", "id": "GO:0048741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048741", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" }, { "name": "regulation of sarcomere organization", "id": "GO:0060297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060297", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "E9QIN8", "url": "https://www.uniprot.org/uniprotkb/E9QIN8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "E9QJQ6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1119, "chemical_mass": 120038.0, "gene_names": "megf10", "protein_name": "Multiple epidermal growth factor-like domains protein 10", "disease": [], "cellular_component": [ { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" }, { "name": "engulfment of apoptotic cell", "id": "GO:0043652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043652", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" }, { "name": "cell development", "id": "GO:0048468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048468", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" }, { "name": "myoblast migration", "id": "GO:0051451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051451", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" }, { "name": "positive regulation of muscle tissue development", "id": "GO:1901863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901863", "evidence": [ { "database": "UniProtKB", "id": "E9QJQ6", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Asn197", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 197, "start_aa": "Asn", "end_pos": 197, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn197", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Asn272", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 272, "start_aa": "Asn", "end_pos": 272, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn272", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Asn369", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 369, "start_aa": "Asn", "end_pos": 369, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn369", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "393", "end_pos": "393", "site_lbl": "Asn393", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 393, "start_aa": "Asn", "end_pos": 393, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn393", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "447", "end_pos": "447", "site_lbl": "Asn447", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 447, "start_aa": "Asn", "end_pos": 447, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn447", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Asn492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 492, "start_aa": "Asn", "end_pos": 492, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn492", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "576", "end_pos": "576", "site_lbl": "Asn576", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 576, "start_aa": "Asn", "end_pos": 576, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn576", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "674", "end_pos": "674", "site_lbl": "Asn674", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 674, "start_aa": "Asn", "end_pos": 674, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn674", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "E9QJQ6-1", "start_pos": "803", "end_pos": "803", "site_lbl": "Asn803", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 803, "start_aa": "Asn", "end_pos": 803, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn803", "evidence": [ { "id": "E9QJQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJQ6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q5B5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q5B5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 561, "chemical_mass": 62469.0, "gene_names": "alpl;Akp2;alpl;alp;zgc:56672", "protein_name": "Alkaline phosphatase", "disease": [ { "disease_id": "DOID:0110913", "name": "adult hypophosphatasia", "description": "A hypophosphatasia that has_material_basis_in a heterozygous or compound heterozygous mutation of the ALPL gene on chromosome 1p36.12.", "url": "https://disease-ontology.org/term/DOID:0110913", "evidence": [ { "id": "0110913", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110913" } ], "weight": 0.0 }, { "disease_id": "DOID:0110914", "name": "infantile hypophosphatasia", "description": "A hypophosphatasia that has_material_basis_in homozygous or compound heterozygosity mutation in the gene encoding tissue-nonspecific alkaline phosphatase (ALPL) on chromosome 1p36.", "url": "https://disease-ontology.org/term/DOID:0110914", "evidence": [ { "id": "0110914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110914" } ], "weight": 0.0 }, { "disease_id": "DOID:0110915", "name": "childhood hypophosphatasia", "description": "A hypophosphatasia that has_material_basis_in an autosomal recessive mutation of the ALPL gene on chromosome 1p36.12.", "url": "https://disease-ontology.org/term/DOID:0110915", "evidence": [ { "id": "0110915", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110915" } ], "weight": 0.0 }, { "disease_id": "DOID:13809", "name": "familial combined hyperlipidemia", "description": "", "url": "https://disease-ontology.org/term/DOID:13809", "evidence": [ { "id": "13809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13809" } ], "weight": 0.0 }, { "disease_id": "DOID:14213", "name": "hypophosphatasia", "description": "A syndrome characterized by disruption of mineralization of bones and teeth that has_material_basis_in mutation in the ALPL gene on chromosome 1p36.12.", "url": "https://disease-ontology.org/term/DOID:14213", "evidence": [ { "id": "14213", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14213" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:8719", "name": "in situ carcinoma", "description": "A carcinoma that is an early development defined by the absence of invasion of surrounding tissues.", "url": "https://disease-ontology.org/term/DOID:8719", "evidence": [ { "id": "8719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8719" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "alkaline phosphatase activity", "id": "GO:0004035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004035", "evidence": [ { "database": "UniProtKB", "id": "F1Q5B5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1Q5B5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1Q5B5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B5" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "F1Q5B5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B5" } ], "pmid": "" } ], "biological_process": [ { "name": "response to mechanical stimulus", "id": "GO:0009612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009612", "evidence": [ { "database": "UniProtKB", "id": "F1Q5B5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B5" } ], "pmid": "" }, { "name": "biomineral tissue development", "id": "GO:0031214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031214", "evidence": [ { "database": "UniProtKB", "id": "F1Q5B5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B5" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "F1Q5B5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q797-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q797", "url": "https://www.uniprot.org/uniprotkb/F1Q797" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 369, "chemical_mass": 42960.0, "gene_names": "fut9b.3;fut9b.3;zgc:103510", "protein_name": "Fucosyltransferase", "disease": [ { "disease_id": "DOID:1508", "name": "candidiasis", "description": "An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.", "url": "https://disease-ontology.org/term/DOID:1508", "evidence": [ { "id": "1508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1508" } ], "weight": 0.0 } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F1Q797", "url": "https://www.uniprot.org/uniprotkb/F1Q797" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "F1Q797", "url": "https://www.uniprot.org/uniprotkb/F1Q797" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "F1Q797", "url": "https://www.uniprot.org/uniprotkb/F1Q797" } ], "pmid": "" } ], "molecular_function": [ { "name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity", "id": "GO:0017083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017083", "evidence": [ { "database": "UniProtKB", "id": "F1Q797", "url": "https://www.uniprot.org/uniprotkb/F1Q797" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q7N0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 572, "chemical_mass": 63369.0, "gene_names": "fpgs;fk51d09;fpgs;wu:fk49h03;wu:fk51d09;zgc:63807", "protein_name": "Folylpolyglutamate synthase", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" }, { "name": "tetrahydrofolylpolyglutamate synthase activity", "id": "GO:0004326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004326", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" } ], "biological_process": [ { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" }, { "name": "tetrahydrofolylpolyglutamate biosynthetic process", "id": "GO:0046901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046901", "evidence": [ { "database": "UniProtKB", "id": "F1Q7N0", "url": "https://www.uniprot.org/uniprotkb/F1Q7N0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q890-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 818, "chemical_mass": 91634.0, "gene_names": "plg;plg;wu:fb70e09", "protein_name": "Plasminogen", "disease": [ { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:0111592", "name": "plasminogen deficiency type I", "description": "A syndrome characterized by decreased serum plasminogen activity, decreased plasminogen antigen levels, and chronic mucosal pseudomembranous lesions typically manifesting as ligneous conjunctivitis that has_material_basis_in homozygous or compound heterozygous mutation in PLG on chromosome 6q26.", "url": "https://disease-ontology.org/term/DOID:0111592", "evidence": [ { "id": "0111592", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111592" } ], "weight": 0.0 }, { "disease_id": "DOID:10159", "name": "osteonecrosis", "description": "An ischemic bone disease that results_in necrosis located_in bone.", "url": "https://disease-ontology.org/term/DOID:10159", "evidence": [ { "id": "10159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10159" } ], "weight": 0.0 }, { "disease_id": "DOID:14735", "name": "hereditary angioedema", "description": "An angioedema that is characterized by recurrent episodes of severe swelling of the skin and mucous membranes.", "url": "https://disease-ontology.org/term/DOID:14735", "evidence": [ { "id": "14735", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14735" } ], "weight": 0.0 }, { "disease_id": "DOID:2452", "name": "thrombophilia", "description": "A blood coagulation disease that is characterized by an increased tendency to form clots.", "url": "https://disease-ontology.org/term/DOID:2452", "evidence": [ { "id": "2452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2452" } ], "weight": 0.0 }, { "disease_id": "DOID:3490", "name": "Noonan syndrome", "description": "A RASopathy that is characterized by mildly unusual facial features, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms.", "url": "https://disease-ontology.org/term/DOID:3490", "evidence": [ { "id": "3490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3490" } ], "weight": 0.0 }, { "disease_id": "DOID:6195", "name": "conjunctivitis", "description": "A conjunctival disease characterized by an inflammation of the conjunctiva, the outermost layer of the eye and the inner surface of the eyelids.", "url": "https://disease-ontology.org/term/DOID:6195", "evidence": [ { "id": "6195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6195" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "pmid": "" }, { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "pmid": "" }, { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "pmid": "" }, { "name": "fibrinolysis", "id": "GO:0042730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042730", "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "pmid": "" }, { "name": "tissue remodeling", "id": "GO:0048771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048771", "evidence": [ { "database": "UniProtKB", "id": "F1Q890", "url": "https://www.uniprot.org/uniprotkb/F1Q890" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1Q890-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Thr475", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 475, "start_aa": "Thr", "end_pos": 475, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr475", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q8C3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 505, "chemical_mass": 57380.0, "gene_names": "cyp2k6;cyp2k6;zgc:66225", "protein_name": "Cytochrome P450 2K6", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "pmid": "" } ], "biological_process": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "pmid": "" }, { "name": "aflatoxin metabolic process", "id": "GO:0046222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046222", "evidence": [ { "database": "UniProtKB", "id": "F1Q8C3", "url": "https://www.uniprot.org/uniprotkb/F1Q8C3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q8J0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 505, "chemical_mass": 56943.0, "gene_names": "rnpc3;rnpc3;zgc:136847", "protein_name": "RNA-binding region-containing protein 3", "disease": [ { "disease_id": "DOID:0061016", "name": "combined or isolated pituitary growth hormone deficiency 7", "description": "A combined pituitary hormone deficiency that has_material_basis_in compound heterozygous mutation in the RNPC3 gene on chromosome 1p21.", "url": "https://disease-ontology.org/term/DOID:0061016", "evidence": [ { "id": "0061016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061016" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "pre-mRNA intronic binding", "id": "GO:0097157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097157", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" }, { "name": "U12 snRNA binding", "id": "GO:0030626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030626", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" } ], "biological_process": [ { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" }, { "name": "pancreas development", "id": "GO:0031016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031016", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" }, { "name": "digestive tract development", "id": "GO:0048565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048565", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" } ], "cellular_component": [ { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1Q8J0", "url": "https://www.uniprot.org/uniprotkb/F1Q8J0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q8R9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q8R9", "url": "https://www.uniprot.org/uniprotkb/F1Q8R9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 756, "chemical_mass": 85711.0, "gene_names": "pomt2;im:7153045;pomt2;zPOMT2;zgc:158749", "protein_name": "Protein O-mannosyl-transferase 2", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0050560", "name": "Walker-Warburg syndrome", "description": "A congenital muscular dystrophy that is characterized by hypotonia, seizures, severe intellectual and developmental disability, eye abnormalities and early death and has_material_basis_in mutations in multiple genes including POMT1, POMT2, ISPD, FKTN, FKRP, and LARGE1.", "url": "https://disease-ontology.org/term/DOID:0050560", "evidence": [ { "id": "0050560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050560" } ], "weight": 0.0 }, { "disease_id": "DOID:0110274", "name": "autosomal recessive limb-girdle muscular dystrophy", "description": "A limb-girdle muscular dystrophy has_material_basis_in autosomal recessive inheritance.", "url": "https://disease-ontology.org/term/DOID:0110274", "evidence": [ { "id": "0110274", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110274" } ], "weight": 0.0 }, { "disease_id": "DOID:0110298", "name": "autosomal recessive limb-girdle muscular dystrophy type 2N", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the POMT2 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0110298", "evidence": [ { "id": "0110298", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110298" } ], "weight": 0.0 }, { "disease_id": "DOID:0111240", "name": "congenital muscular dystrophy-dystroglycanopathy type A2", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in POMT2 on 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0111240", "evidence": [ { "id": "0111240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111240" } ], "weight": 0.0 }, { "disease_id": "DOID:0112374", "name": "muscular dystrophy-dystroglycanopathy", "description": "A congenital muscular dystrophy characterized by muscular dystrophy resulting from defective glycosylation of dystroglycan.", "url": "https://disease-ontology.org/term/DOID:0112374", "evidence": [ { "id": "0112374", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112374" } ], "weight": 0.0 }, { "disease_id": "DOID:0112380", "name": "muscular dystrophy-dystroglycanopathy type B2", "description": "A muscular dystrophy-dystroglycanopathy type B that has_material_basis_in homozygous or compound heterozygous mutation in the POMT2 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0112380", "evidence": [ { "id": "0112380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112380" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "F1Q8R9", "url": "https://www.uniprot.org/uniprotkb/F1Q8R9" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1Q8R9", "url": "https://www.uniprot.org/uniprotkb/F1Q8R9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1Q8R9", "url": "https://www.uniprot.org/uniprotkb/F1Q8R9" } ], "pmid": "" } ], "biological_process": [ { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "F1Q8R9", "url": "https://www.uniprot.org/uniprotkb/F1Q8R9" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "F1Q8R9", "url": "https://www.uniprot.org/uniprotkb/F1Q8R9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1Q8T9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 340, "chemical_mass": 38689.0, "gene_names": "cxcr2;cxcr2", "protein_name": "C-X-C chemokine receptor type 2", "disease": [ { "disease_id": "DOID:0060973", "name": "WHIM syndrome 2", "description": "An immunodeficiency disease that is characterized by chronic neutropenia and myelokathexis, which is impaired neutrophil mobilization from the bone marrow and that has_material_basis_in homozygous mutation in the CXCR2 gene on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:0060973", "evidence": [ { "id": "0060973", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060973" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:559", "name": "acute pyelonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:559", "evidence": [ { "id": "559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:559" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "neutrophil activation", "id": "GO:0042119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042119", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "neutrophil chemotaxis", "id": "GO:0030593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030593", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "neutrophil migration", "id": "GO:1990266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990266", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" } ], "molecular_function": [ { "name": "C-C chemokine receptor activity", "id": "GO:0016493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016493", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "C-X-C chemokine receptor activity", "id": "GO:0016494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016494", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "C-C chemokine binding", "id": "GO:0019957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019957", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" }, { "name": "granulocyte colony-stimulating factor binding", "id": "GO:0051916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051916", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "F1Q8T9", "url": "https://www.uniprot.org/uniprotkb/F1Q8T9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QAM1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QAM1", "url": "https://www.uniprot.org/uniprotkb/F1QAM1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 345, "chemical_mass": 39888.0, "gene_names": "zdhhc4;dhhc4;zgc:64155", "protein_name": "Palmitoyltransferase ZDHHC4", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1QAM1", "url": "https://www.uniprot.org/uniprotkb/F1QAM1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1QAM1", "url": "https://www.uniprot.org/uniprotkb/F1QAM1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1QAM1", "url": "https://www.uniprot.org/uniprotkb/F1QAM1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QAM1", "url": "https://www.uniprot.org/uniprotkb/F1QAM1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1QAM1", "url": "https://www.uniprot.org/uniprotkb/F1QAM1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "F1QAM1", "url": "https://www.uniprot.org/uniprotkb/F1QAM1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "F1QAM1", "url": "https://www.uniprot.org/uniprotkb/F1QAM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QB54-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 634, "chemical_mass": 70734.0, "gene_names": "pabpc1a;PABP-1A;pabpc1a;pabpc1;wu:fb16a02;wu:fi19b08;wu:fj12d09;wu:fj61f06;zgc:109879", "protein_name": "Polyadenylate-binding protein 1A", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" }, { "name": "poly(U) RNA binding", "id": "GO:0008266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266", "evidence": [ { "database": "UniProtKB", "id": "F1QB54", "url": "https://www.uniprot.org/uniprotkb/F1QB54" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QBP9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 430, "chemical_mass": 48226.0, "gene_names": "nthl1;NTHL1;nthl1", "protein_name": "Endonuclease III-like protein 1", "disease": [ { "disease_id": "DOID:0080411", "name": "familial adenomatous polyposis 3", "description": "A familial adenomatous polyposis that has_material_basis_in homozygous or compound heterozygous mutation in the NTHL1 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0080411", "evidence": [ { "id": "0080411", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080411" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" }, { "name": "class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0140078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140078", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" }, { "name": "oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity", "id": "GO:0000703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000703", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" }, { "name": "base-excision repair, AP site formation", "id": "GO:0006285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006285", "evidence": [ { "database": "UniProtKB", "id": "F1QBP9", "url": "https://www.uniprot.org/uniprotkb/F1QBP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QCC6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 554, "chemical_mass": 61296.0, "gene_names": "gpc1;zgc:122977", "protein_name": "Glypican-1", "disease": [ { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "negative regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0040037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040037", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "intrahepatic bile duct development", "id": "GO:0035622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035622", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "common bile duct development", "id": "GO:0061009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061009", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" }, { "name": "regulation of protein localization to membrane", "id": "GO:1905475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905475", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" } ], "molecular_function": [ { "name": "fibroblast growth factor binding", "id": "GO:0017134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017134", "evidence": [ { "database": "UniProtKB", "id": "F1QCC6", "url": "https://www.uniprot.org/uniprotkb/F1QCC6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QCC6-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QCC6-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Xyl...) (heparan sulfate) serine", "icn3d_view": {}, "start_pos": 490, "start_aa": "Ser", "end_pos": 490, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser490", "evidence": [ { "id": "F1QCC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QCC6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "F1QCC6-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Ser492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Xyl...) (heparan sulfate) serine", "icn3d_view": {}, "start_pos": 492, "start_aa": "Ser", "end_pos": 492, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser492", "evidence": [ { "id": "F1QCC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QCC6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "F1QCC6-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Ser494", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (Xyl...) (heparan sulfate) serine", "icn3d_view": {}, "start_pos": 494, "start_aa": "Ser", "end_pos": 494, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser494", "evidence": [ { "id": "F1QCC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QCC6#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QEG2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 605, "chemical_mass": 68713.0, "gene_names": "klhl41b;cb52;kbtbd10b;kbtbd10;klhl41b;sarcosin;sb:cb52;wu:fb24f05;wu:fc15e07", "protein_name": "Kelch-like protein 41b", "disease": [ { "disease_id": "DOID:0110929", "name": "nemaline myopathy 9", "description": "A nemaline myopathy characterized by onset in early infancy of muscle weakness with variable severity that has_material_basis_in homozygous or compound heterozygous mutation in the KLHL41 gene on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0110929", "evidence": [ { "id": "0110929", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110929" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:3191", "name": "nemaline myopathy", "description": "A congenital myopathy characterized by generally non-progressive muscle weakness of varying severity and problems with the tone and contraction of skeletal muscles. The muscle cells contain abnormal clumps of threadlike material called nemaline bodies.", "url": "https://disease-ontology.org/term/DOID:3191", "evidence": [ { "id": "3191", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3191" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" }, { "name": "skeletal muscle fiber development", "id": "GO:0048741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048741", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" }, { "name": "regulation of sarcomere organization", "id": "GO:0060297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060297", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "F1QEG2", "url": "https://www.uniprot.org/uniprotkb/F1QEG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QF89-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QF89", "url": "https://www.uniprot.org/uniprotkb/F1QF89" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 720, "chemical_mass": 82084.0, "gene_names": "pomt1;pomt1;zPOMT1;zgc:153731", "protein_name": "Protein O-mannosyl-transferase 1", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0050560", "name": "Walker-Warburg syndrome", "description": "A congenital muscular dystrophy that is characterized by hypotonia, seizures, severe intellectual and developmental disability, eye abnormalities and early death and has_material_basis_in mutations in multiple genes including POMT1, POMT2, ISPD, FKTN, FKRP, and LARGE1.", "url": "https://disease-ontology.org/term/DOID:0050560", "evidence": [ { "id": "0050560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050560" } ], "weight": 0.0 }, { "disease_id": "DOID:0050588", "name": "muscular dystrophy-dystroglycanopathy type B1", "description": "A congenital muscular dystrophy characterized by muscle weakness, cognitive impairment and brain abnormalities and has_material_basis_in mutation to the POMT1 gene that encodes O-mannosyltransferase.", "url": "https://disease-ontology.org/term/DOID:0050588", "evidence": [ { "id": "0050588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050588" } ], "weight": 0.0 }, { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:0110297", "name": "autosomal recessive limb-girdle muscular dystrophy type 2K", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding protein O-mannosyltransferase (POMT1).", "url": "https://disease-ontology.org/term/DOID:0110297", "evidence": [ { "id": "0110297", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110297" } ], "weight": 0.0 }, { "disease_id": "DOID:0111237", "name": "congenital muscular dystrophy-dystroglycanopathy type A1", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in POMT1 on 9q34.13.", "url": "https://disease-ontology.org/term/DOID:0111237", "evidence": [ { "id": "0111237", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111237" } ], "weight": 0.0 }, { "disease_id": "DOID:0112374", "name": "muscular dystrophy-dystroglycanopathy", "description": "A congenital muscular dystrophy characterized by muscular dystrophy resulting from defective glycosylation of dystroglycan.", "url": "https://disease-ontology.org/term/DOID:0112374", "evidence": [ { "id": "0112374", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112374" } ], "weight": 0.0 }, { "disease_id": "DOID:9296", "name": "cleft lip", "description": "An orofacial cleft that is characterized by a congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences.", "url": "https://disease-ontology.org/term/DOID:9296", "evidence": [ { "id": "9296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9296" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "F1QF89", "url": "https://www.uniprot.org/uniprotkb/F1QF89" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of skeletal muscle fiber development", "id": "GO:0048742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048742", "evidence": [ { "database": "UniProtKB", "id": "F1QF89", "url": "https://www.uniprot.org/uniprotkb/F1QF89" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "F1QF89", "url": "https://www.uniprot.org/uniprotkb/F1QF89" } ], "pmid": "" }, { "name": "regulation of eye photoreceptor cell development", "id": "GO:0042478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042478", "evidence": [ { "database": "UniProtKB", "id": "F1QF89", "url": "https://www.uniprot.org/uniprotkb/F1QF89" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1QF89", "url": "https://www.uniprot.org/uniprotkb/F1QF89" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1QF89", "url": "https://www.uniprot.org/uniprotkb/F1QF89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QFU9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 414, "chemical_mass": 47089.0, "gene_names": "dpep1;dpep1;zgc:153024", "protein_name": "Dipeptidase", "disease": [ { "disease_id": "DOID:687", "name": "hepatoblastoma", "description": "", "url": "https://disease-ontology.org/term/DOID:687", "evidence": [ { "id": "687", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:687" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" }, { "name": "metallodipeptidase activity", "id": "GO:0070573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070573", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" }, { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" }, { "name": "beta-lactamase activity", "id": "GO:0008800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008800", "evidence": [ { "database": "UniProtKB", "id": "F1QFU9", "url": "https://www.uniprot.org/uniprotkb/F1QFU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QGC8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QGC8", "url": "https://www.uniprot.org/uniprotkb/F1QGC8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 207, "chemical_mass": 23037.0, "gene_names": "dtd1;dtd1;dtd;hars2;zgc:92657", "protein_name": "D-aminoacyl-tRNA deacylase 1", "disease": [], "biological_process": [ { "name": "tRNA metabolic process", "id": "GO:0006399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006399", "evidence": [ { "database": "UniProtKB", "id": "F1QGC8", "url": "https://www.uniprot.org/uniprotkb/F1QGC8" } ], "pmid": "" } ], "molecular_function": [ { "name": "D-tyrosyl-tRNA(Tyr) deacylase activity", "id": "GO:0051500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051500", "evidence": [ { "database": "UniProtKB", "id": "F1QGC8", "url": "https://www.uniprot.org/uniprotkb/F1QGC8" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "F1QGC8", "url": "https://www.uniprot.org/uniprotkb/F1QGC8" } ], "pmid": "" }, { "name": "Gly-tRNA(Ala) deacylase activity", "id": "GO:0106026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106026", "evidence": [ { "database": "UniProtKB", "id": "F1QGC8", "url": "https://www.uniprot.org/uniprotkb/F1QGC8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QGC8", "url": "https://www.uniprot.org/uniprotkb/F1QGC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QGC8-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 14, "start_aa": "Thr", "end_pos": 14, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr14", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QGC8-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Thr152", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 152, "start_aa": "Thr", "end_pos": 152, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr152", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QGU0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QGU0", "url": "https://www.uniprot.org/uniprotkb/F1QGU0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 306, "chemical_mass": 33285.0, "gene_names": "pgp;cb241;pgp;sb:cb241;wu:fb92c03;wu:fi40b02;zgc:56011", "protein_name": "Glycerol-3-phosphate phosphatase", "disease": [], "biological_process": [ { "name": "glycerophospholipid metabolic process", "id": "GO:0006650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006650", "evidence": [ { "database": "UniProtKB", "id": "F1QGU0", "url": "https://www.uniprot.org/uniprotkb/F1QGU0" } ], "pmid": "" }, { "name": "glycerol biosynthetic process", "id": "GO:0006114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006114", "evidence": [ { "database": "UniProtKB", "id": "F1QGU0", "url": "https://www.uniprot.org/uniprotkb/F1QGU0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QGU0", "url": "https://www.uniprot.org/uniprotkb/F1QGU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1QGU0", "url": "https://www.uniprot.org/uniprotkb/F1QGU0" } ], "pmid": "" }, { "name": "sn-glycerol 3-phosphatase activity", "id": "GO:0043136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043136", "evidence": [ { "database": "UniProtKB", "id": "F1QGU0", "url": "https://www.uniprot.org/uniprotkb/F1QGU0" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "F1QGU0", "url": "https://www.uniprot.org/uniprotkb/F1QGU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QGW6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 472, "chemical_mass": 51221.0, "gene_names": "eif2s3;Su(var)3-9;eif2s3;fi03g03;wu:fi03g03;wu:fi37d04;zgc:63805", "protein_name": "Eukaryotic translation initiation factor 2 subunit 3", "disease": [ { "disease_id": "DOID:0060801", "name": "MEHMO syndrome", "description": "A syndromic X-linked intellectual disability characterized by severe intellectual deficit, epilepsy, microcephaly, hypogenitalism and obesity with variable occurrence of growth delay and diabetes that has_material_basis_in hemizygous mutation in the EIF2S3 gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:0060801", "evidence": [ { "id": "0060801", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060801" } ], "weight": 0.0 }, { "disease_id": "DOID:10579", "name": "leukodystrophy", "description": "A cerebral degeneration characterized by dysfunction of the white matter of the brain.", "url": "https://disease-ontology.org/term/DOID:10579", "evidence": [ { "id": "10579", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10579" } ], "weight": 0.0 }, { "disease_id": "DOID:4194", "name": "glucose metabolism disease", "description": "A carbohydrate metabolic disorder that is characterized by blood glucose levels which cannot be maintained within the normal range.", "url": "https://disease-ontology.org/term/DOID:4194", "evidence": [ { "id": "4194", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4194" } ], "weight": 0.0 }, { "disease_id": "DOID:9406", "name": "hypopituitarism", "description": "A pituitary gland disease characterized by the decreased secretion of one or more of the eight hormones normally produced by the pituitary gland.", "url": "https://disease-ontology.org/term/DOID:9406", "evidence": [ { "id": "9406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9406" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cytoplasmic translational initiation", "id": "GO:0002183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002183", "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "pmid": "" }, { "name": "methionyl-initiator methionine tRNA binding", "id": "GO:1990856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990856", "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2 complex", "id": "GO:0005850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005850", "evidence": [ { "database": "UniProtKB", "id": "F1QGW6", "url": "https://www.uniprot.org/uniprotkb/F1QGW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QHZ6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 778, "chemical_mass": 86391.0, "gene_names": "dnai4;dnai4;wdr78;zgc:111979", "protein_name": "Dynein axonemal intermediate chain 4", "disease": [ { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "pmid": "" }, { "name": "axonemal dynein complex", "id": "GO:0005858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005858", "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "pmid": "" }, { "name": "dynein axonemal particle", "id": "GO:0120293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120293", "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "dynein light chain binding", "id": "GO:0045503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045503", "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "pmid": "" }, { "name": "dynein heavy chain binding", "id": "GO:0045504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045504", "evidence": [ { "database": "UniProtKB", "id": "F1QHZ6", "url": "https://www.uniprot.org/uniprotkb/F1QHZ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QJB6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 3091, "chemical_mass": 348812.0, "gene_names": "atm;atm", "protein_name": "non-specific serine/threonine protein kinase", "disease": [ { "disease_id": "DOID:0050671", "name": "female breast cancer", "description": "A breast cancer that develops from breast tissue in females.", "url": "https://disease-ontology.org/term/DOID:0050671", "evidence": [ { "id": "0050671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050671" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12704", "name": "ataxia telangiectasia", "description": "An autosomal recessive cerebellar ataxia that is characterized by cerebellar ataxia, telangiectases, immune defects, and a predisposition to malignancy and that has_material_basis_in homozygous or compound heterozygous mutation in the ATM gene on chromosome 11q22.", "url": "https://disease-ontology.org/term/DOID:12704", "evidence": [ { "id": "12704", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12704" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:8634", "name": "prostate carcinoma in situ", "description": "An in situ carcinoma that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:8634", "evidence": [ { "id": "8634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8634" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 }, { "disease_id": "DOID:9655", "name": "oral mucosa leukoplakia", "description": "A mouth disease that is characterized by a white patch or plaque that develops in the oral cavity and is strongly associated with smoking.", "url": "https://disease-ontology.org/term/DOID:9655", "evidence": [ { "id": "9655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9655" } ], "weight": 0.0 }, { "disease_id": "DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging.", "url": "https://disease-ontology.org/term/DOID:9669", "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of macromolecule biosynthetic process", "id": "GO:0010557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010557", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010389", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "regulation of telomere maintenance via telomerase", "id": "GO:0032210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032210", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "positive regulation of telomere maintenance via telomere lengthening", "id": "GO:1904358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904358", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "positive regulation of programmed cell death", "id": "GO:0043068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043068", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "meiosis I", "id": "GO:0007127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007127", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "cellular response to oxygen-containing compound", "id": "GO:1901701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901701", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1QJB6", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QJB6-1", "start_pos": "2935", "end_pos": "2935", "site_lbl": "Thr2935", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2935, "start_aa": "Thr", "end_pos": 2935, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2935", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QJB6-1", "start_pos": "3019", "end_pos": "3019", "site_lbl": "Thr3019", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3019, "start_aa": "Thr", "end_pos": 3019, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3019", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QJG0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 454, "chemical_mass": 51111.0, "gene_names": "nr5a1a;SF1-A;ff1b;nr5a1a;nr5a4", "protein_name": "", "disease": [ { "disease_id": "DOID:0070169", "name": "spermatogenic failure 8", "description": "A spermatogenic failure that is characterized by autosomal dominant inheritance of azoospermia or moderate to severe oligozoospermia that has_material_basis_in heterozygous mutation in the NR5A1 gene on chromosome 9q33.", "url": "https://disease-ontology.org/term/DOID:0070169", "evidence": [ { "id": "0070169", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070169" } ], "weight": 0.0 }, { "disease_id": "DOID:0080864", "name": "primary ovarian insufficiency 7", "description": "A primary ovarian insufficiency that has_material_basis_in heterozygous mutation in the NR5A1 gene on chromosome 9q33.", "url": "https://disease-ontology.org/term/DOID:0080864", "evidence": [ { "id": "0080864", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080864" } ], "weight": 0.0 }, { "disease_id": "DOID:0090070", "name": "hypogonadotropic hypogonadism", "description": "A hypogonadism characterized by a impaired signalling by gonadotrpin relasing hormone.", "url": "https://disease-ontology.org/term/DOID:0090070", "evidence": [ { "id": "0090070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090070" } ], "weight": 0.0 }, { "disease_id": "DOID:0111764", "name": "46,XX sex reversal 4", "description": "A 46,XX sex reversal that has_material_basis_in heterozygous mutation in the NR5A1 gene on chromosome 9q33.3.", "url": "https://disease-ontology.org/term/DOID:0111764", "evidence": [ { "id": "0111764", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111764" } ], "weight": 0.0 }, { "disease_id": "DOID:0111772", "name": "46,XY sex reversal 3", "description": "A 46 XY sex reversal characterized by an XY karyotype, phenotypically female genitalia and failure to develop secondary sexual characteristics at puberty including menstruation that has_material_basis_in heterozygous mutation in the NR5A1 gene on chromosome 9q33.3.", "url": "https://disease-ontology.org/term/DOID:0111772", "evidence": [ { "id": "0111772", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111772" } ], "weight": 0.0 }, { "disease_id": "DOID:14447", "name": "gonadal dysgenesis", "description": "A disorder of sexual development that is characterized by a progressive loss of germ cells on the developing gonads of an embryo.", "url": "https://disease-ontology.org/term/DOID:14447", "evidence": [ { "id": "14447", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14447" } ], "weight": 0.0 }, { "disease_id": "DOID:905", "name": "Zellweger syndrome", "description": "A peroxisomal biogenesis disorder that is characterized by severe neurologic dysfunction, craniofacial abnormalities, and liver dysfunction, and biochemically by the absence of peroxisome and that has_material_basis_in autosomal recessive inheritance of a mutation in the peroxisome biogenesis factor (PEX) genes.", "url": "https://disease-ontology.org/term/DOID:905", "evidence": [ { "id": "905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:905" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "adrenal gland development", "id": "GO:0030325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030325", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" }, { "name": "hypothalamus development", "id": "GO:0021854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021854", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "F1QJG0", "url": "https://www.uniprot.org/uniprotkb/F1QJG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QJL4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1011, "chemical_mass": 112745.0, "gene_names": "lig3;im:7139055;im:7145225;lig3;wu:fb12c02;wu:fd10b03;wu:fm79b09;zgc:112973", "protein_name": "DNA ligase", "disease": [ { "disease_id": "DOID:0070451", "name": "mitochondrial DNA depletion syndrome 20", "description": "A mitochondrial DNA depletion syndrome characterized by variable neurogastrointestinal encephalopathy including severe gastrointestinal dysmotility, neurogenic bladder, muscle weakness and atrophy, headaches, stroke-like episodes, seizures, pyramidal signs, and learning difficulties or cognitive decline that has_material_basis_in compound heterozygous mutation in the LIG3 gene on chromosome 17q12.", "url": "https://disease-ontology.org/term/DOID:0070451", "evidence": [ { "id": "0070451", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070451" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA biosynthetic process", "id": "GO:0071897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071897", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "lagging strand elongation", "id": "GO:0006273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006273", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "double-strand break repair via alternative nonhomologous end joining", "id": "GO:0097681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097681", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "negative regulation of DNA metabolic process", "id": "GO:0051053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051053", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "mitochondrial DNA repair", "id": "GO:0043504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043504", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" }, { "name": "DNA ligase (ATP) activity", "id": "GO:0003910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003910", "evidence": [ { "database": "UniProtKB", "id": "F1QJL4", "url": "https://www.uniprot.org/uniprotkb/F1QJL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QK82-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1062, "chemical_mass": 119482.0, "gene_names": "kif11;cb1;chunp6874;fa09c03;fb23c07;kif11;knsl1;sb:cb1;wu:fa09c03;wu:fb23c07", "protein_name": "", "disease": [ { "disease_id": "DOID:0060349", "name": "microcephaly with or without chorioretinopathy, lymphedema, or mental retardation", "description": "A syndrome characterized by variable expression of microcephaly, ocular disorders including chorioretinopathy, congenital lymphedema of the lower limbs, and mild to moderate intellectual disability.", "url": "https://disease-ontology.org/term/DOID:0060349", "evidence": [ { "id": "0060349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060349" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "spindle elongation", "id": "GO:0051231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051231", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "F1QK82", "url": "https://www.uniprot.org/uniprotkb/F1QK82" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QKH1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 188, "chemical_mass": 20853.0, "gene_names": "slc31a1;ctr-1;ctr1;slc31a1;zgc:76839", "protein_name": "Copper transport protein", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 } ], "biological_process": [ { "name": "copper ion transmembrane transport", "id": "GO:0035434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035434", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "response to copper ion", "id": "GO:0046688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046688", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "copper ion transport", "id": "GO:0006825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006825", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "copper ion import", "id": "GO:0015677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015677", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "hypotonic salinity response", "id": "GO:0042539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042539", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" } ], "molecular_function": [ { "name": "copper ion transmembrane transporter activity", "id": "GO:0005375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005375", "evidence": [ { "database": "UniProtKB", "id": "F1QKH1", "url": "https://www.uniprot.org/uniprotkb/F1QKH1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QKJ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 818, "chemical_mass": 92694.0, "gene_names": "ntrk3a;ntrk3a;trkC1", "protein_name": "Tyrosine-protein kinase receptor", "disease": [ { "disease_id": "DOID:0080202", "name": "adenoid cystic carcinoma", "description": "An adenocarcinoma that is characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells.", "url": "https://disease-ontology.org/term/DOID:0080202", "evidence": [ { "id": "0080202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080202" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "neurotrophin binding", "id": "GO:0043121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043121", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "neurotrophin receptor activity", "id": "GO:0005030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005030", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "cellular response to nerve growth factor stimulus", "id": "GO:1990090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990090", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "F1QKJ0", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QKJ0-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Thr407", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 407, "start_aa": "Thr", "end_pos": 407, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr407", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QL52-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 4219, "chemical_mass": 456723.0, "gene_names": "kmt2a;im:7148357;kmt2a;mll", "protein_name": "Histone-lysine N-methyltransferase", "disease": [ { "disease_id": "DOID:0060060", "name": "non-Hodgkin lymphoma", "description": "A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma.", "url": "https://disease-ontology.org/term/DOID:0060060", "evidence": [ { "id": "0060060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060060" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4971", "name": "myelofibrosis", "description": "A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.", "url": "https://disease-ontology.org/term/DOID:4971", "evidence": [ { "id": "4971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4971" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glial cell development", "id": "GO:0021782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021782", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "paraxial mesoderm development", "id": "GO:0048339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048339", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "nucleate erythrocyte development", "id": "GO:0048823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048823", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" }, { "name": "histone H3K4 monomethyltransferase activity", "id": "GO:0140945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140945", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" } ], "cellular_component": [ { "name": "histone methyltransferase complex", "id": "GO:0035097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "evidence": [ { "database": "UniProtKB", "id": "F1QL52", "url": "https://www.uniprot.org/uniprotkb/F1QL52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "1294", "end_pos": "1294", "site_lbl": "Thr1294", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1294, "start_aa": "Thr", "end_pos": 1294, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1294", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "1576", "end_pos": "1576", "site_lbl": "Thr1576", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1576, "start_aa": "Thr", "end_pos": 1576, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1576", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "2036", "end_pos": "2036", "site_lbl": "Thr2036", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2036, "start_aa": "Thr", "end_pos": 2036, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2036", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "2784", "end_pos": "2784", "site_lbl": "Thr2784", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2784, "start_aa": "Thr", "end_pos": 2784, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2784", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Thr487", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 487, "start_aa": "Thr", "end_pos": 487, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr487", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Thr490", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 490, "start_aa": "Thr", "end_pos": 490, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr490", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Thr506", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 506, "start_aa": "Thr", "end_pos": 506, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr506", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "625", "end_pos": "625", "site_lbl": "Thr625", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 625, "start_aa": "Thr", "end_pos": 625, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr625", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QL52-1", "start_pos": "895", "end_pos": "895", "site_lbl": "Thr895", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 895, "start_aa": "Thr", "end_pos": 895, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr895", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QNB2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QNB2", "url": "https://www.uniprot.org/uniprotkb/F1QNB2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 653, "chemical_mass": 75010.0, "gene_names": "pomgnt1;im:7151461;pomgnt1;zPOMGnT1;zgc:158130", "protein_name": "Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0050560", "name": "Walker-Warburg syndrome", "description": "A congenital muscular dystrophy that is characterized by hypotonia, seizures, severe intellectual and developmental disability, eye abnormalities and early death and has_material_basis_in mutations in multiple genes including POMT1, POMT2, ISPD, FKTN, FKRP, and LARGE1.", "url": "https://disease-ontology.org/term/DOID:0050560", "evidence": [ { "id": "0050560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050560" } ], "weight": 0.0 }, { "disease_id": "DOID:0050588", "name": "muscular dystrophy-dystroglycanopathy type B1", "description": "A congenital muscular dystrophy characterized by muscle weakness, cognitive impairment and brain abnormalities and has_material_basis_in mutation to the POMT1 gene that encodes O-mannosyltransferase.", "url": "https://disease-ontology.org/term/DOID:0050588", "evidence": [ { "id": "0050588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050588" } ], "weight": 0.0 }, { "disease_id": "DOID:0061103", "name": "retinitis pigmentosa 76", "description": "A retinitis pigmentosa that has_material_basis_in homozygous or compound heterozygous mutation in the POMGNT1 gene on chromosome 1p34.", "url": "https://disease-ontology.org/term/DOID:0061103", "evidence": [ { "id": "0061103", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061103" } ], "weight": 0.0 }, { "disease_id": "DOID:0110292", "name": "autosomal recessive limb-girdle muscular dystrophy type 2O", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous mutation in the gene encoding protein O-mannose beta-1,2-N-acetylglucosaminyltransferase (POMGNT1) on chromosome 1p34.", "url": "https://disease-ontology.org/term/DOID:0110292", "evidence": [ { "id": "0110292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110292" } ], "weight": 0.0 }, { "disease_id": "DOID:0111236", "name": "congenital muscular dystrophy-dystroglycanopathy type A3", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in POMGNT1 on 1p34.1.", "url": "https://disease-ontology.org/term/DOID:0111236", "evidence": [ { "id": "0111236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111236" } ], "weight": 0.0 }, { "disease_id": "DOID:0112378", "name": "muscular dystrophy-dystroglycanopathy type B3", "description": "A muscular dystrophy-dystroglycanopathy type B that has_material_basis_in homozygous or compound heterozygous mutation in the POMGNT1 gene on chromosome 1p34.1.", "url": "https://disease-ontology.org/term/DOID:0112378", "evidence": [ { "id": "0112378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112378" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "secretory vesicle", "id": "GO:0099503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099503", "evidence": [ { "database": "UniProtKB", "id": "F1QNB2", "url": "https://www.uniprot.org/uniprotkb/F1QNB2" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1QNB2", "url": "https://www.uniprot.org/uniprotkb/F1QNB2" } ], "pmid": "" } ], "molecular_function": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "F1QNB2", "url": "https://www.uniprot.org/uniprotkb/F1QNB2" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "F1QNB2", "url": "https://www.uniprot.org/uniprotkb/F1QNB2" } ], "pmid": "" }, { "name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity", "id": "GO:0047223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047223", "evidence": [ { "database": "UniProtKB", "id": "F1QNB2", "url": "https://www.uniprot.org/uniprotkb/F1QNB2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "F1QNB2", "url": "https://www.uniprot.org/uniprotkb/F1QNB2" } ], "pmid": "" }, { "name": "eye morphogenesis", "id": "GO:0048592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048592", "evidence": [ { "database": "UniProtKB", "id": "F1QNB2", "url": "https://www.uniprot.org/uniprotkb/F1QNB2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QNB2-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Thr463", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 463, "start_aa": "Thr", "end_pos": 463, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr463", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P0C928-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1177, "chemical_mass": 132804.0, "gene_names": "rtel1;RTEL1;zgc:113114", "protein_name": "Regulator of telomere elongation helicase 1", "disease": [ { "disease_id": "DOID:0050671", "name": "female breast cancer", "description": "A breast cancer that develops from breast tissue in females.", "url": "https://disease-ontology.org/term/DOID:0050671", "evidence": [ { "id": "0050671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050671" } ], "weight": 0.0 }, { "disease_id": "DOID:0070022", "name": "autosomal recessive dyskeratosis congenita 5", "description": "A dyskeratosis congenita that has_material_basis_in an autosomal recessive mutation of the RTEL1 gene on chromosome 20q13.33.", "url": "https://disease-ontology.org/term/DOID:0070022", "evidence": [ { "id": "0070022", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070022" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10325", "name": "silicosis", "description": "A pneumoconiosis that is an inflammation and scarring of the upper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles.", "url": "https://disease-ontology.org/term/DOID:10325", "evidence": [ { "id": "10325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10325" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3079", "name": "childhood astrocytic tumor", "description": "", "url": "https://disease-ontology.org/term/DOID:3079", "evidence": [ { "id": "3079", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3079" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:5076", "name": "mixed glioma", "description": "", "url": "https://disease-ontology.org/term/DOID:5076", "evidence": [ { "id": "5076", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5076" } ], "weight": 0.0 } ], "biological_process": [ { "name": "telomeric loop disassembly", "id": "GO:0090657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090657", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "negative regulation of t-circle formation", "id": "GO:1904430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904430", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "negative regulation of DNA recombination", "id": "GO:0045910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045910", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "regulation of double-strand break repair via homologous recombination", "id": "GO:0010569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010569", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "DNA polymerase binding", "id": "GO:0070182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070182", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides", "id": "GO:0016818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016818", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P0C928", "url": "https://www.uniprot.org/uniprotkb/P0C928" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QP24-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 641, "chemical_mass": 72433.0, "gene_names": "myb;c-myb;cmyb;myb", "protein_name": "Transcriptional activator Myb", "disease": [ { "disease_id": "DOID:0050523", "name": "adult T-cell leukemia/lymphoma", "description": "A T-cell acute leukemia that results_in abnormal increase of lymphocytes, derives_from T-cells, has_material_basis_in human T-cell leukemia virus type 1 (Deltaretrovirus priTlym1), which is transmitted_by sexual contact, transmitted_by contaminated needles used by intravenous-drug users, and transmitted_by breast feeding. The infection results_in_formation_of skin lesions.", "url": "https://disease-ontology.org/term/DOID:0050523", "evidence": [ { "id": "0050523", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050523" } ], "weight": 0.0 }, { "disease_id": "DOID:0080630", "name": "B-lymphoblastic leukemia/lymphoma", "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow.", "url": "https://disease-ontology.org/term/DOID:0080630", "evidence": [ { "id": "0080630", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080630" } ], "weight": 0.0 }, { "disease_id": "DOID:2224", "name": "essential thrombocythemia", "description": "A myeloproliferative neoplasm that is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage and that results_in the overproduction of platelets.", "url": "https://disease-ontology.org/term/DOID:2224", "evidence": [ { "id": "2224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2224" } ], "weight": 0.0 }, { "disease_id": "DOID:4971", "name": "myelofibrosis", "description": "A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.", "url": "https://disease-ontology.org/term/DOID:4971", "evidence": [ { "id": "4971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4971" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "neutrophil homeostasis", "id": "GO:0001780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001780", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "myeloid cell development", "id": "GO:0061515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061515", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "hematopoietic stem cell migration", "id": "GO:0035701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035701", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "regulation of neutrophil differentiation", "id": "GO:0045658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045658", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1QP24", "url": "https://www.uniprot.org/uniprotkb/F1QP24" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QP24-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Thr208", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1QP24-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Thr439", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 439, "start_aa": "Thr", "end_pos": 439, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr439", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QPF7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QPF7", "url": "https://www.uniprot.org/uniprotkb/F1QPF7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 404, "chemical_mass": 44283.0, "gene_names": "cth;cth;fb58d08;wu:fb48e03;wu:fb58d08;zgc:66001;zgc:85785", "protein_name": "Cystathionine gamma-lyase", "disease": [ { "disease_id": "DOID:0090142", "name": "cystathioninuria", "description": "An amino acid metabolic disorder that is characterized by elevated plasma and urinary cystathionine levels that has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the gene encoding cystathionine gamma-lyase (CTH) on chromosome 1p31.", "url": "https://disease-ontology.org/term/DOID:0090142", "evidence": [ { "id": "0090142", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090142" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QPF7", "url": "https://www.uniprot.org/uniprotkb/F1QPF7" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "F1QPF7", "url": "https://www.uniprot.org/uniprotkb/F1QPF7" } ], "pmid": "" }, { "name": "cystathionine gamma-lyase activity", "id": "GO:0004123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004123", "evidence": [ { "database": "UniProtKB", "id": "F1QPF7", "url": "https://www.uniprot.org/uniprotkb/F1QPF7" } ], "pmid": "" }, { "name": "homocysteine desulfhydrase activity", "id": "GO:0047982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047982", "evidence": [ { "database": "UniProtKB", "id": "F1QPF7", "url": "https://www.uniprot.org/uniprotkb/F1QPF7" } ], "pmid": "" } ], "biological_process": [ { "name": "transsulfuration", "id": "GO:0019346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019346", "evidence": [ { "database": "UniProtKB", "id": "F1QPF7", "url": "https://www.uniprot.org/uniprotkb/F1QPF7" } ], "pmid": "" }, { "name": "cysteine biosynthetic process via cystathionine", "id": "GO:0019343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019343", "evidence": [ { "database": "UniProtKB", "id": "F1QPF7", "url": "https://www.uniprot.org/uniprotkb/F1QPF7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QR98-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QR98", "url": "https://www.uniprot.org/uniprotkb/F1QR98" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 308, "chemical_mass": 34700.0, "gene_names": "fam212aa;fam212aa;inka1a;sb:cb528;wu:fk96h10;zgc:136369;zgc:158531", "protein_name": "PAK4-inhibitor inka1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QR98", "url": "https://www.uniprot.org/uniprotkb/F1QR98" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QR98", "url": "https://www.uniprot.org/uniprotkb/F1QR98" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1QR98", "url": "https://www.uniprot.org/uniprotkb/F1QR98" } ], "pmid": "" }, { "name": "protein serine/threonine kinase inhibitor activity", "id": "GO:0030291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030291", "evidence": [ { "database": "UniProtKB", "id": "F1QR98", "url": "https://www.uniprot.org/uniprotkb/F1QR98" } ], "pmid": "" } ], "biological_process": [ { "name": "cartilage condensation", "id": "GO:0001502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001502", "evidence": [ { "database": "UniProtKB", "id": "F1QR98", "url": "https://www.uniprot.org/uniprotkb/F1QR98" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "F1QR98", "url": "https://www.uniprot.org/uniprotkb/F1QR98" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QSP4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 154, "chemical_mass": 15694.0, "gene_names": "atp6v0ca;CHUNP6904;atp6l;atp6v0ca;atp6v0c;cb993;fb57d09;wu:fb57d09", "protein_name": "V-type proton ATPase proteolipid subunit", "disease": [ { "disease_id": "DOID:0070472", "name": "early-onset epilepsy 3", "description": "An epilepsy characterized by infantile or childhood onset of various types of seizures with variable global developmental delay and intellectual disability that has_material_basis_in heterozygous mutation in the ATP6V0C gene on chromosome 16p13.3.", "url": "https://disease-ontology.org/term/DOID:0070472", "evidence": [ { "id": "0070472", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070472" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:3963", "name": "thyroid gland carcinoma", "description": "A thyroid gland cancer that has_material_basis_in epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3963", "evidence": [ { "id": "3963", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3963" } ], "weight": 0.0 } ], "biological_process": [ { "name": "embryonic retina morphogenesis in camera-type eye", "id": "GO:0060059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060059", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" }, { "name": "response to yeast", "id": "GO:0001878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001878", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" }, { "name": "apical protein localization", "id": "GO:0045176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045176", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" }, { "name": "notochord cell vacuolation", "id": "GO:0060036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060036", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" }, { "name": "proton-transporting V-type ATPase, V0 domain", "id": "GO:0033179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033179", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "F1QSP4", "url": "https://www.uniprot.org/uniprotkb/F1QSP4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QSR7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 422, "chemical_mass": 47789.0, "gene_names": "panx1b;PANX;panx1b;si:ch211-69i14.7", "protein_name": "Pannexin", "disease": [ { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "gap junction", "id": "GO:0005921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "monoatomic cation transport", "id": "GO:0006812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006812", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "positive regulation of interleukin-1 production", "id": "GO:0032732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032732", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" } ], "molecular_function": [ { "name": "channel activity", "id": "GO:0015267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015267", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "wide pore channel activity", "id": "GO:0022829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022829", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" }, { "name": "voltage-gated channel activity", "id": "GO:0022832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022832", "evidence": [ { "database": "UniProtKB", "id": "F1QSR7", "url": "https://www.uniprot.org/uniprotkb/F1QSR7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QSR7-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Asn246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 246, "start_aa": "Asn", "end_pos": 246, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn246", "evidence": [ { "id": "F1QSR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QSR7#ptm_processing" }, { "id": "PIRSR600990-51", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR600990-51" } ] } ] }, { "uniprot_canonical_ac": "F1QSR7-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Asn71", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 71, "start_aa": "Asn", "end_pos": 71, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn71", "evidence": [ { "id": "F1QSR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QSR7#ptm_processing" }, { "id": "PIRSR600990-52", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR600990-52" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QU45-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 572, "chemical_mass": 65277.0, "gene_names": "bco2a;bco2a", "protein_name": "Carotenoid-cleaving dioxygenase, mitochondrial", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "pmid": "" }, { "name": "beta-carotene 15,15'-dioxygenase activity", "id": "GO:0003834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003834", "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "pmid": "" }, { "name": "carotenoid dioxygenase activity", "id": "GO:0010436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010436", "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "pmid": "" }, { "name": "beta,beta-carotene-9',10'-cleaving oxygenase activity", "id": "GO:0102076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102076", "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "pmid": "" }, { "name": "dioxygenase activity", "id": "GO:0051213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "pmid": "" } ], "biological_process": [ { "name": "retinal metabolic process", "id": "GO:0042574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042574", "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "pmid": "" }, { "name": "carotene catabolic process", "id": "GO:0016121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016121", "evidence": [ { "database": "UniProtKB", "id": "F1QU45", "url": "https://www.uniprot.org/uniprotkb/F1QU45" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QUK5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 602, "chemical_mass": 67448.0, "gene_names": "ntn1b;net1;ntn1b;ntn1", "protein_name": "Netrin-1", "disease": [ { "disease_id": "DOID:0070638", "name": "mirror movements 4", "description": "A congenital mirror movement disorder that has_material_basis_in heterozygous mutation in the NTN1 gene on chromosome 17p13.", "url": "https://disease-ontology.org/term/DOID:0070638", "evidence": [ { "id": "0070638", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070638" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" } ], "biological_process": [ { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" }, { "name": "regulation of axon extension", "id": "GO:0030516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030516", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" }, { "name": "central nervous system projection neuron axonogenesis", "id": "GO:0021952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" }, { "name": "olfactory bulb axon guidance", "id": "GO:0071678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071678", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" }, { "name": "anterior commissure morphogenesis", "id": "GO:0021960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021960", "evidence": [ { "database": "UniProtKB", "id": "F1QUK5", "url": "https://www.uniprot.org/uniprotkb/F1QUK5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QUK5-1", "start_pos": "469", "end_pos": "469", "site_lbl": "Thr469", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 469, "start_aa": "Thr", "end_pos": 469, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr469", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QV34-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 823, "chemical_mass": 92229.0, "gene_names": "kif17;kif17", "protein_name": "Kinesin-like protein", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "dendrite cytoplasm", "id": "GO:0032839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032839", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" } ], "biological_process": [ { "name": "photoreceptor cell outer segment organization", "id": "GO:0035845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035845", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "eye photoreceptor cell development", "id": "GO:0042462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042462", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "anterograde dendritic transport of neurotransmitter receptor complex", "id": "GO:0098971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098971", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "F1QV34", "url": "https://www.uniprot.org/uniprotkb/F1QV34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QVR8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 207, "chemical_mass": 23146.0, "gene_names": "mettl5;im:7137598;mettl5;zgc:103655", "protein_name": "rRNA N(6)-adenosine-methyltransferase METTL5", "disease": [ { "disease_id": "DOID:0080765", "name": "autosomal recessive intellectual developmental disorder 72", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the METTL5 gene on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0080765", "evidence": [ { "id": "0080765", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080765" } ], "weight": 0.0 } ], "biological_process": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" }, { "name": "stem cell differentiation", "id": "GO:0048863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048863", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" }, { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" }, { "name": "S-adenosyl-L-methionine binding", "id": "GO:1904047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904047", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" }, { "name": "rRNA (adenine-N6-)-methyltransferase activity", "id": "GO:0008988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008988", "evidence": [ { "database": "UniProtKB", "id": "F1QVR8", "url": "https://www.uniprot.org/uniprotkb/F1QVR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QW76-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 124, "chemical_mass": 13843.0, "gene_names": "batf;B-ATF;batf;si:ch211-153j24.4", "protein_name": "Basic leucine zipper transcriptional factor ATF-like", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "hematopoietic stem cell differentiation", "id": "GO:0060218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "isotype switching", "id": "GO:0045190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045190", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "lymphoid progenitor cell differentiation", "id": "GO:0002320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002320", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "defense response to protozoan", "id": "GO:0042832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042832", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "myeloid dendritic cell differentiation", "id": "GO:0043011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043011", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "T-helper 2 cell differentiation", "id": "GO:0045064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045064", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "T-helper 17 cell differentiation", "id": "GO:0072539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072539", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "T-helper 17 cell lineage commitment", "id": "GO:0072540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072540", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1QW76", "url": "https://www.uniprot.org/uniprotkb/F1QW76" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QWZ4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QWZ4", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 389, "chemical_mass": 45080.0, "gene_names": "gdf2;BMP-9;GDF-2;bmp9;gdf2", "protein_name": "Growth/differentiation factor 2", "disease": [ { "disease_id": "DOID:1270", "name": "hereditary hemorrhagic telangiectasia", "description": "A vascular disease characterized by the presence of multiple arteriovenous malformations that lack intervening capillaries and result in direct connections between arteries and veins.", "url": "https://disease-ontology.org/term/DOID:1270", "evidence": [ { "id": "1270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1270" } ], "weight": 0.0 } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "F1QWZ4", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell proliferation", "id": "GO:0001938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001938", "evidence": [ { "database": "UniProtKB", "id": "F1QWZ4", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "F1QWZ4", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1QWZ4", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "F1QWZ4", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "F1QWZ4", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1QWZ4-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Asn118", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 118, "start_aa": "Asn", "end_pos": 118, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "F1QWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "F1QWZ4-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Asn127", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 127, "start_aa": "Asn", "end_pos": 127, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn127", "evidence": [ { "id": "F1QWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "F1QWZ4-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Asn232", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 232, "start_aa": "Asn", "end_pos": 232, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn232", "evidence": [ { "id": "F1QWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "F1QWZ4-1", "start_pos": "342", "end_pos": "342", "site_lbl": "Asn342", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 342, "start_aa": "Asn", "end_pos": 342, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn342", "evidence": [ { "id": "F1QWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "F1QWZ4-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Asn65", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 65, "start_aa": "Asn", "end_pos": 65, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn65", "evidence": [ { "id": "F1QWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QWZ4#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QXZ9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 466, "chemical_mass": 52361.0, "gene_names": "smad9;sma8;smad9;zgc:103407", "protein_name": "Mothers against decapentaplegic homolog", "disease": [ { "disease_id": "DOID:0050787", "name": "juvenile polyposis syndrome", "description": "A gastrointestinal system disease that is characterized by predisposition to hamartomatous benign polyps in the gastrointestinal tract, specifically in the stomach, small intestine, colon, and rectum.", "url": "https://disease-ontology.org/term/DOID:0050787", "evidence": [ { "id": "0050787", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050787" } ], "weight": 0.0 }, { "disease_id": "DOID:0060688", "name": "arteriovenous malformations of the brain", "description": "A central nervous system benign neoplasm that derives_from endothelial cells and that is located_in the brain.", "url": "https://disease-ontology.org/term/DOID:0060688", "evidence": [ { "id": "0060688", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060688" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:14557", "name": "primary pulmonary hypertension", "description": "A chronic pulmonary heart disease characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein, or pulmonary capillaries, among others, has symptoms shortness of breath, dizziness, fainting, leg swelling.", "url": "https://disease-ontology.org/term/DOID:14557", "evidence": [ { "id": "14557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14557" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "heteromeric SMAD protein complex", "id": "GO:0071144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071144", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "SMAD protein signal transduction", "id": "GO:0060395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060395", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "regulation of BMP signaling pathway", "id": "GO:0030510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030510", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "myeloid cell development", "id": "GO:0061515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061515", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" }, { "name": "I-SMAD binding", "id": "GO:0070411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070411", "evidence": [ { "database": "UniProtKB", "id": "F1QXZ9", "url": "https://www.uniprot.org/uniprotkb/F1QXZ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1QYJ6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QYJ6", "url": "https://www.uniprot.org/uniprotkb/F1QYJ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 296, "chemical_mass": 33995.0, "gene_names": "sult6b1", "protein_name": "Sulfotransferase 6B1", "disease": [], "molecular_function": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "F1QYJ6", "url": "https://www.uniprot.org/uniprotkb/F1QYJ6" } ], "pmid": "" } ], "biological_process": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "F1QYJ6", "url": "https://www.uniprot.org/uniprotkb/F1QYJ6" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "F1QYJ6", "url": "https://www.uniprot.org/uniprotkb/F1QYJ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1QYJ6", "url": "https://www.uniprot.org/uniprotkb/F1QYJ6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1QYJ6", "url": "https://www.uniprot.org/uniprotkb/F1QYJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R013-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 386, "chemical_mass": 42793.0, "gene_names": "zdhhc9;DHHC-9;dhcc9;zdhhc9;zgc:136936", "protein_name": "Palmitoyltransferase ZDHHC9", "disease": [ { "disease_id": "DOID:0060824", "name": "syndromic X-linked intellectual disability Raymond type", "description": "A syndromic X-linked intellectual disability characterized by intellectual disability and marfanoid habitus that has_material_basis_in mutation in the ZDHHC9 gene on chromosome Xq26.1.", "url": "https://disease-ontology.org/term/DOID:0060824", "evidence": [ { "id": "0060824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060824" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "pmid": "" }, { "name": "peptidyl-L-cysteine S-palmitoylation", "id": "GO:0018230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018230", "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "pmid": "" }, { "name": "positive regulation of pyroptotic inflammatory response", "id": "GO:0140639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140639", "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "F1R013", "url": "https://www.uniprot.org/uniprotkb/F1R013" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R0H0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R0H0", "url": "https://www.uniprot.org/uniprotkb/F1R0H0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 513, "chemical_mass": 55944.0, "gene_names": "slc2a10;GLUT-10;glut10;slc2a10;zgc:171488", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 10", "disease": [ { "disease_id": "DOID:0050645", "name": "arterial tortuosity syndrome", "description": "A connective tissue disease that is characterized by elongation and generalized tortuosity of the major arteries including the aorta.", "url": "https://disease-ontology.org/term/DOID:0050645", "evidence": [ { "id": "0050645", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050645" } ], "weight": 0.0 } ], "biological_process": [ { "name": "circulatory system development", "id": "GO:0072359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072359", "evidence": [ { "database": "UniProtKB", "id": "F1R0H0", "url": "https://www.uniprot.org/uniprotkb/F1R0H0" } ], "pmid": "" }, { "name": "D-glucose transmembrane transport", "id": "GO:1904659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904659", "evidence": [ { "database": "UniProtKB", "id": "F1R0H0", "url": "https://www.uniprot.org/uniprotkb/F1R0H0" } ], "pmid": "" }, { "name": "notochord development", "id": "GO:0030903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030903", "evidence": [ { "database": "UniProtKB", "id": "F1R0H0", "url": "https://www.uniprot.org/uniprotkb/F1R0H0" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1R0H0", "url": "https://www.uniprot.org/uniprotkb/F1R0H0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1R0H0", "url": "https://www.uniprot.org/uniprotkb/F1R0H0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1R0H0", "url": "https://www.uniprot.org/uniprotkb/F1R0H0" } ], "pmid": "" } ], "molecular_function": [ { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "F1R0H0", "url": "https://www.uniprot.org/uniprotkb/F1R0H0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1R0H0-1", "start_pos": "270", "end_pos": "270", "site_lbl": "Asn270", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 270, "start_aa": "Asn", "end_pos": 270, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn270", "evidence": [ { "id": "F1R0H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R0H0#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "F1R0H0-1", "start_pos": "341", "end_pos": "341", "site_lbl": "Asn341", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 341, "start_aa": "Asn", "end_pos": 341, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn341", "evidence": [ { "id": "F1R0H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R0H0#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R293-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 482, "chemical_mass": 54579.0, "gene_names": "adsl;adsl;fi60b04;wu:fi60b04;zgc:56061", "protein_name": "Adenylosuccinate lyase", "disease": [ { "disease_id": "DOID:0050762", "name": "adenylosuccinase lyase deficiency", "description": "An amino acid metabolic disorder that is characterized by microcephaly, aggressive behavior, cerebellar hypoplasia and seizures, has_material_basis_in autosomal recessive inheritance of mutation in the ADSL gene resulting in adenylosuccinate lyase deficiency.", "url": "https://disease-ontology.org/term/DOID:0050762", "evidence": [ { "id": "0050762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050762" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "pmid": "" }, { "name": "'de novo' IMP biosynthetic process", "id": "GO:0006189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006189", "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "pmid": "" }, { "name": "'de novo' AMP biosynthetic process", "id": "GO:0044208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044208", "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "pmid": "" } ], "molecular_function": [ { "name": "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity", "id": "GO:0004018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004018", "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "pmid": "" }, { "name": "(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity", "id": "GO:0070626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070626", "evidence": [ { "database": "UniProtKB", "id": "F1R293", "url": "https://www.uniprot.org/uniprotkb/F1R293" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P79732-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 794, "chemical_mass": 89816.0, "gene_names": "rrm1;CHUNP6866;cb396;cb838;r1;sb:cb548;wu:fb39b07;wu:fi14b02;wu:fk95f07", "protein_name": "Ribonucleoside-diphosphate reductase large subunit", "disease": [ { "disease_id": "DOID:12558", "name": "chronic progressive external ophthalmoplegia", "description": "A mitochondrial myopathy characterized by weakness of extraocular muscles, usually evident from bilateral ptosis and/or ophthalmoplegia, that has_material_basis_in mitochondrial DNA deletions.", "url": "https://disease-ontology.org/term/DOID:12558", "evidence": [ { "id": "12558", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12558" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" }, { "name": "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor", "id": "GO:0004748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004748", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" }, { "name": "ribonucleoside-diphosphate reductase complex", "id": "GO:0005971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005971", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" } ], "biological_process": [ { "name": "deoxyribonucleotide biosynthetic process", "id": "GO:0009263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009263", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" }, { "name": "positive regulation of G0 to G1 transition", "id": "GO:0070318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070318", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" }, { "name": "mitochondrial DNA replication", "id": "GO:0006264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006264", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" }, { "name": "ribonucleoside diphosphate metabolic process", "id": "GO:0009185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009185", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" }, { "name": "2'-deoxyribonucleotide biosynthetic process", "id": "GO:0009265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009265", "evidence": [ { "database": "UniProtKB", "id": "P79732", "url": "https://www.uniprot.org/uniprotkb/P79732" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P79732-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Thr604", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 604, "start_aa": "Thr", "end_pos": 604, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr604", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R3J9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 348, "chemical_mass": 40116.0, "gene_names": "prmt1;fb39h07;hrmt1l2;prmt1;wu:fb39h07;zf1;zgc:66201", "protein_name": "type I protein arginine methyltransferase", "disease": [ { "disease_id": "DOID:674", "name": "cleft palate", "description": "An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.", "url": "https://disease-ontology.org/term/DOID:674", "evidence": [ { "id": "674", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:674" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "convergent extension involved in gastrulation", "id": "GO:0060027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060027", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "histone H4R3 methyltransferase activity", "id": "GO:0044020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044020", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "protein-arginine omega-N monomethyltransferase activity", "id": "GO:0035241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035241", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" }, { "name": "arginine N-methyltransferase activity", "id": "GO:0016273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016273", "evidence": [ { "database": "UniProtKB", "id": "F1R3J9", "url": "https://www.uniprot.org/uniprotkb/F1R3J9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R7R1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R7R1", "url": "https://www.uniprot.org/uniprotkb/F1R7R1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1099, "chemical_mass": 123812.0, "gene_names": "smg5;est1b;smg5;zgc:113841", "protein_name": "Nonsense-mediated mRNA decay factor SMG5", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1R7R1", "url": "https://www.uniprot.org/uniprotkb/F1R7R1" } ], "pmid": "" }, { "name": "telomerase holoenzyme complex", "id": "GO:0005697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005697", "evidence": [ { "database": "UniProtKB", "id": "F1R7R1", "url": "https://www.uniprot.org/uniprotkb/F1R7R1" } ], "pmid": "" } ], "molecular_function": [ { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "F1R7R1", "url": "https://www.uniprot.org/uniprotkb/F1R7R1" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "F1R7R1", "url": "https://www.uniprot.org/uniprotkb/F1R7R1" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "F1R7R1", "url": "https://www.uniprot.org/uniprotkb/F1R7R1" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "F1R7R1", "url": "https://www.uniprot.org/uniprotkb/F1R7R1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1R7R1-1", "start_pos": "682", "end_pos": "682", "site_lbl": "Thr682", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 682, "start_aa": "Thr", "end_pos": 682, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr682", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R8E2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1475, "chemical_mass": 163916.0, "gene_names": "ptch1;lep;ptc1;ptc2;ptch1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050860", "name": "colorectal adenoma", "description": "An intestinal benign neoplasm that has_material_basis_in epithelial tissue of glandular origin and is located_in colon and located_in rectum.", "url": "https://disease-ontology.org/term/DOID:0050860", "evidence": [ { "id": "0050860", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050860" } ], "weight": 0.0 }, { "disease_id": "DOID:0050902", "name": "medulloblastoma", "description": "An infratentorial cancer that is located_in the lower part of the brain and is a type of primitive neuroectodermal tumor.", "url": "https://disease-ontology.org/term/DOID:0050902", "evidence": [ { "id": "0050902", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050902" } ], "weight": 0.0 }, { "disease_id": "DOID:0070365", "name": "nevoid basal cell carcinoma syndrome 1", "description": "A nevoid basal cell carcinoma syndrome that has_material_basis_in heterozygous mutation in the PTCH1 gene on chromosome 9q22.", "url": "https://disease-ontology.org/term/DOID:0070365", "evidence": [ { "id": "0070365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070365" } ], "weight": 0.0 }, { "disease_id": "DOID:0080016", "name": "spina bifida", "description": "A neural tube defect that is characterized by incomplete closing of the spine and membranes around the spinal cord during early development.", "url": "https://disease-ontology.org/term/DOID:0080016", "evidence": [ { "id": "0080016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080016" } ], "weight": 0.0 }, { "disease_id": "DOID:0110876", "name": "holoprosencephaly 7", "description": "A holoprosencephaly that has_material_basis_in heterozygous mutation in the PTCH1 gene on chromosome 9q22.", "url": "https://disease-ontology.org/term/DOID:0110876", "evidence": [ { "id": "0110876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110876" } ], "weight": 0.0 }, { "disease_id": "DOID:10460", "name": "nasopharyngitis", "description": "A nasopharyngeal disease which involves inflammation of the nasal passages and upper part of the pharynx.", "url": "https://disease-ontology.org/term/DOID:10460", "evidence": [ { "id": "10460", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10460" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2512", "name": "nevoid basal cell carcinoma syndrome", "description": "A syndrome characterized by multiple early-onset basal cell carcinoma, multiple jaw keratocysts and skeletal abnormalities.", "url": "https://disease-ontology.org/term/DOID:2512", "evidence": [ { "id": "2512", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2512" } ], "weight": 0.0 }, { "disease_id": "DOID:2513", "name": "basal cell carcinoma", "description": "A skin carcinoma affecting basal cells.", "url": "https://disease-ontology.org/term/DOID:2513", "evidence": [ { "id": "2513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2513" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.", "url": "https://disease-ontology.org/term/DOID:4621", "evidence": [ { "id": "4621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ], "weight": 0.0 }, { "disease_id": "DOID:4948", "name": "gallbladder carcinoma", "description": "A gallbladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4948", "evidence": [ { "id": "4948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4948" } ], "weight": 0.0 }, { "disease_id": "DOID:5522", "name": "basaloid squamous cell carcinoma", "description": "A squamous cell carcinoma that has a solid, closely packed growth of cells with hyperchromatic nuclei, scant cytoplasm, small cystic spaces, and foci of necrosis. It has overlying squamous dysplasia, rare foci of overt keratinization, and/or coexistent keratinizing squamous cell carcinoma.", "url": "https://disease-ontology.org/term/DOID:5522", "evidence": [ { "id": "5522", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5522" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of muscle organ development", "id": "GO:0048635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048635", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" }, { "name": "retina morphogenesis in camera-type eye", "id": "GO:0060042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060042", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" }, { "name": "intramembranous ossification", "id": "GO:0001957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001957", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" }, { "name": "cardioblast differentiation", "id": "GO:0010002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010002", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" } ], "molecular_function": [ { "name": "hedgehog receptor activity", "id": "GO:0008158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008158", "evidence": [ { "database": "UniProtKB", "id": "F1R8E2", "url": "https://www.uniprot.org/uniprotkb/F1R8E2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1R8E2-1", "start_pos": "1209", "end_pos": "1209", "site_lbl": "Thr1209", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1209, "start_aa": "Thr", "end_pos": 1209, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1209", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R8P4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 449, "chemical_mass": 51569.0, "gene_names": "glra2", "protein_name": "Glycine receptor subunit alpha-2", "disease": [], "molecular_function": [ { "name": "transmitter-gated monoatomic ion channel activity", "id": "GO:0022824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022824", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" }, { "name": "glycine binding", "id": "GO:0016594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016594", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" }, { "name": "excitatory extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005231", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" } ], "cellular_component": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" } ], "biological_process": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "F1R8P4", "url": "https://www.uniprot.org/uniprotkb/F1R8P4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1R8P4-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Asn70", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 70, "start_aa": "Asn", "end_pos": 70, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "F1R8P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R8P4#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1R8Z9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 442, "chemical_mass": 50006.0, "gene_names": "foxj1b;fj67h07;foxj1.2;foxj1b;wu:fj67h07;zgc:101713", "protein_name": "Forkhead box protein J1-B", "disease": [ { "disease_id": "DOID:0050144", "name": "Kartagener syndrome", "description": "A primary ciliary dyskinesia that is characterized by sinusitis, bronchiectasis and situs inversus with dextrocardia resulting from dysfunction of the cilia during embryologic development.", "url": "https://disease-ontology.org/term/DOID:0050144", "evidence": [ { "id": "0050144", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050144" } ], "weight": 0.0 }, { "disease_id": "DOID:0111856", "name": "primary ciliary dyskinesia 43", "description": "A primary ciliary dyskinesia characterized by reduced generation of multiple motile cilia, onset of respiratory insufficiency soon after birth, recurrent upper and lower respiratory infections,variable infertility, and laterality defects in about half of patients that has_material_basis_in heterozygous mutation in FOXJ1 on chromosome 17q25.1.", "url": "https://disease-ontology.org/term/DOID:0111856", "evidence": [ { "id": "0111856", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111856" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" }, { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" }, { "name": "auditory receptor cell stereocilium organization", "id": "GO:0060088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060088", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" }, { "name": "heart jogging", "id": "GO:0003146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003146", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1R8Z9", "url": "https://www.uniprot.org/uniprotkb/F1R8Z9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1RAK0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 681, "chemical_mass": 75331.0, "gene_names": "acsl5;acsl5;zgc:92083", "protein_name": "Long-chain-fatty-acid--CoA ligase", "disease": [ { "disease_id": "DOID:0060774", "name": "congenital diarrhea", "description": "A diarrhea that is characterized by frequent loose or liquid bowel movements where the disease is present from birth.", "url": "https://disease-ontology.org/term/DOID:0060774", "evidence": [ { "id": "0060774", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060774" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "pmid": "" }, { "name": "arachidonate-CoA ligase activity", "id": "GO:0047676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047676", "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "pmid": "" } ], "biological_process": [ { "name": "long-chain fatty-acyl-CoA biosynthetic process", "id": "GO:0035338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035338", "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "pmid": "" }, { "name": "positive regulation of long-chain fatty acid import across plasma membrane", "id": "GO:0010747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010747", "evidence": [ { "database": "UniProtKB", "id": "F1RAK0", "url": "https://www.uniprot.org/uniprotkb/F1RAK0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1RB95-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 459, "chemical_mass": 51971.0, "gene_names": "rnf14;rnf14;wu:fb80d11;wu:fi42d09;zgc:86928", "protein_name": "E3 ubiquitin-protein ligase RNF14", "disease": [], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "protein-RNA covalent cross-linking repair", "id": "GO:0160127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160127", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "F1RB95", "url": "https://www.uniprot.org/uniprotkb/F1RB95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1RCP3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 374, "chemical_mass": 40698.0, "gene_names": "zfp36l1a;cb198;cb480;fk89d11;id:ibd1247;sb:cb198;sb:cb480;wu:fb80h11;wu:fb92f07;wu:fk89d11;zfp36l1a;zfp36l1;zfp36l2;zgc:153979", "protein_name": "mRNA decay activator protein ZFP36", "disease": [], "molecular_function": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": "GO:0000900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" }, { "name": "mRNA 3'-UTR AU-rich region binding", "id": "GO:0035925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035925", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" }, { "name": "protein-RNA sequence-specific adaptor activity", "id": "GO:0160134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160134", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900153", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0000289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000289", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "F1RCP3", "url": "https://www.uniprot.org/uniprotkb/F1RCP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1RCP3-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Thr218", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 218, "start_aa": "Thr", "end_pos": 218, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr218", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F1RCP3-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Thr309", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 309, "start_aa": "Thr", "end_pos": 309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr309", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1RDC0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 275, "chemical_mass": 32130.0, "gene_names": "atg5;apg5l;atg5;zgc:100934", "protein_name": "Autophagy protein 5", "disease": [ { "disease_id": "DOID:0050951", "name": "hereditary ataxia", "description": "A neurodegenerative disease that is characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements.", "url": "https://disease-ontology.org/term/DOID:0050951", "evidence": [ { "id": "0050951", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050951" } ], "weight": 0.0 }, { "disease_id": "DOID:0080259", "name": "autosomal recessive spinocerebellar ataxia 25", "description": "An autosomal recessive cerebellar ataxia that has_material_basis_in homozygous mutation in the ATG5 gene on chromosome 6q21.", "url": "https://disease-ontology.org/term/DOID:0080259", "evidence": [ { "id": "0080259", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080259" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "negative regulation of programmed cell death", "id": "GO:0043069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043069", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "cellular response to nitrogen starvation", "id": "GO:0006995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006995", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "aggrephagy", "id": "GO:0035973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035973", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "regulation of skeletal muscle tissue regeneration", "id": "GO:0043416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043416", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" } ], "cellular_component": [ { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "Atg12-Atg5-Atg16 complex", "id": "GO:0034274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034274", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" }, { "name": "phagophore", "id": "GO:0061908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061908", "evidence": [ { "database": "UniProtKB", "id": "F1RDC0", "url": "https://www.uniprot.org/uniprotkb/F1RDC0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F1REK1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 712, "chemical_mass": 80573.0, "gene_names": "hgfa;hgf1;hgfa;si:dkey-146j3.2", "protein_name": "Hepatocyte growth factor", "disease": [ { "disease_id": "DOID:0050625", "name": "biliary tract benign neoplasm", "description": "A hepatobiliary benign neoplasm located_in the biliary tract.", "url": "https://disease-ontology.org/term/DOID:0050625", "evidence": [ { "id": "0050625", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050625" } ], "weight": 0.0 }, { "disease_id": "DOID:0050852", "name": "limb ischemia", "description": "An ischemia that is characterized by low blood supply to tissues in the limb due to interruption in the arterial blood supply.", "url": "https://disease-ontology.org/term/DOID:0050852", "evidence": [ { "id": "0050852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050852" } ], "weight": 0.0 }, { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:0080745", "name": "polymyositis", "description": "A myositis that is characterized by muscle weakness affecting both sides of your body.", "url": "https://disease-ontology.org/term/DOID:0080745", "evidence": [ { "id": "0080745", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080745" } ], "weight": 0.0 }, { "disease_id": "DOID:0081267", "name": "graft-versus-host disease", "description": "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081267", "evidence": [ { "id": "0081267", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081267" } ], "weight": 0.0 }, { "disease_id": "DOID:0110497", "name": "autosomal recessive nonsyndromic deafness 39", "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with severe to profound, downsloping hearing loss and has_material_basis_in mutation in the HGF gene on chromosome 7q21.", "url": "https://disease-ontology.org/term/DOID:0110497", "evidence": [ { "id": "0110497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110497" } ], "weight": 0.0 }, { "disease_id": "DOID:10126", "name": "keratoconus", "description": "A corneal disease characterized by structural changes within the cornea causing it to thin and change, leading to a protruding conical shape.", "url": "https://disease-ontology.org/term/DOID:10126", "evidence": [ { "id": "10126", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10126" } ], "weight": 0.0 }, { "disease_id": "DOID:10223", "name": "dermatomyositis", "description": "A myositis that results_in inflammation located_in muscle or located_in skin where a skin rash is often seen prior to the onset of muscle weakness. The disease may result from either a viral infection or an autoimmune reaction.", "url": "https://disease-ontology.org/term/DOID:10223", "evidence": [ { "id": "10223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10223" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11830", "name": "myopia", "description": "A refractive error characterized by the inability to see farther objects clearly.", "url": "https://disease-ontology.org/term/DOID:11830", "evidence": [ { "id": "11830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11830" } ], "weight": 0.0 }, { "disease_id": "DOID:12306", "name": "vitiligo", "description": "An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.", "url": "https://disease-ontology.org/term/DOID:12306", "evidence": [ { "id": "12306", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12306" } ], "weight": 0.0 }, { "disease_id": "DOID:13025", "name": "retinopathy of prematurity", "description": "", "url": "https://disease-ontology.org/term/DOID:13025", "evidence": [ { "id": "13025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13025" } ], "weight": 0.0 }, { "disease_id": "DOID:13550", "name": "angle-closure glaucoma", "description": "A glaucoma characterized by closure of the anterior chamber angle such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Angle closure glaucoma can be caused by anatomically narrow angle, injury to the trabecular meshwork, and injuries to the anterior chamber, such as neovascularization and uveitis.", "url": "https://disease-ontology.org/term/DOID:13550", "evidence": [ { "id": "13550", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13550" } ], "weight": 0.0 }, { "disease_id": "DOID:14256", "name": "adult-onset Still's disease", "description": "A rheumatoid arthritis that is characterized by high fevers, rash, sore throat and joint pain.", "url": "https://disease-ontology.org/term/DOID:14256", "evidence": [ { "id": "14256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14256" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2741", "name": "bilirubin metabolic disorder", "description": "An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism.", "url": "https://disease-ontology.org/term/DOID:2741", "evidence": [ { "id": "2741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2741" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3179", "name": "inverted papilloma", "description": "", "url": "https://disease-ontology.org/term/DOID:3179", "evidence": [ { "id": "3179", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3179" } ], "weight": 0.0 }, { "disease_id": "DOID:331", "name": "central nervous system disease", "description": "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system.", "url": "https://disease-ontology.org/term/DOID:331", "evidence": [ { "id": "331", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:331" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 }, { "disease_id": "DOID:3565", "name": "meningioma", "description": "A central nervous system cancer that are manifested in the central nervous system and arise from the arachnoid cap cells of the arachnoid villi in the meninges.", "url": "https://disease-ontology.org/term/DOID:3565", "evidence": [ { "id": "3565", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3565" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:633", "name": "myositis", "description": "A myopathy characterized by muscle inflammation.", "url": "https://disease-ontology.org/term/DOID:633", "evidence": [ { "id": "633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:633" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 }, { "disease_id": "DOID:8472", "name": "localized scleroderma", "description": "", "url": "https://disease-ontology.org/term/DOID:8472", "evidence": [ { "id": "8472", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8472" } ], "weight": 0.0 }, { "disease_id": "DOID:869", "name": "cholesteatoma", "description": "A keratosis that is characterized by keratinizing squamous epithelium located in middle ear and/or mastoid, subepithelial connective tissue and by the progressive accumulation of keratin debris with or without surrounding inflammatory reaction.", "url": "https://disease-ontology.org/term/DOID:869", "evidence": [ { "id": "869", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:869" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9719", "name": "neovascular inflammatory vitreoretinopathy", "description": "A retinal and vitreous disease characterized by ocular inflammation, vascular dropout, large spots of hyperpigmentation, neovascularization of the peripheral and posterior retina, vitreous hemorrhage, and retinal detachment that has_material_basis_in heterozygous mutation in the CAPN5 gene on chromosome 11q13.5.", "url": "https://disease-ontology.org/term/DOID:9719", "evidence": [ { "id": "9719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9719" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "cerebellum morphogenesis", "id": "GO:0021587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021587", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "cerebellum development", "id": "GO:0021549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021549", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "central nervous system neuron differentiation", "id": "GO:0021953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021953", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "hepatocyte growth factor receptor signaling pathway", "id": "GO:0048012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048012", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "cerebellar granule cell differentiation", "id": "GO:0021707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021707", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" }, { "name": "cranial nerve formation", "id": "GO:0021603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021603", "evidence": [ { "database": "UniProtKB", "id": "F1REK1", "url": "https://www.uniprot.org/uniprotkb/F1REK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F1REK1-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Thr302", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 302, "start_aa": "Thr", "end_pos": 302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr302", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F4ZGF2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F4ZGF2", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 256, "chemical_mass": 28719.0, "gene_names": "comta;comta;comt;zgc:114157", "protein_name": "Catechol O-methyltransferase A", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10933", "name": "obsessive-compulsive disorder", "description": "An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions).", "url": "https://disease-ontology.org/term/DOID:10933", "evidence": [ { "id": "10933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10933" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11612", "name": "polycystic ovary syndrome", "description": "An ovarian dysfunction that is characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight.", "url": "https://disease-ontology.org/term/DOID:11612", "evidence": [ { "id": "11612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11612" } ], "weight": 0.0 }, { "disease_id": "DOID:12129", "name": "bulimia nervosa", "description": "An eating disorder characterized by the restraining of food intake for a period of time followed by an over intake or binging period that results in feelings of guilt and low self-esteem.", "url": "https://disease-ontology.org/term/DOID:12129", "evidence": [ { "id": "12129", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12129" } ], "weight": 0.0 }, { "disease_id": "DOID:12306", "name": "vitiligo", "description": "An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.", "url": "https://disease-ontology.org/term/DOID:12306", "evidence": [ { "id": "12306", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12306" } ], "weight": 0.0 }, { "disease_id": "DOID:12399", "name": "pathological gambling", "description": "An impulse control disorder that involves the uncontrollable impulse to gamble, irrespective of the interference the behaviour has on the individual's life.", "url": "https://disease-ontology.org/term/DOID:12399", "evidence": [ { "id": "12399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12399" } ], "weight": 0.0 }, { "disease_id": "DOID:12401", "name": "intermittent explosive disorder", "description": "An impulse control disorder that involves the episodic inability to control violent impulses with a disproportionate degree of aggressiveness.", "url": "https://disease-ontology.org/term/DOID:12401", "evidence": [ { "id": "12401", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12401" } ], "weight": 0.0 }, { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:13078", "name": "eumycotic mycetoma", "description": "A dermatomycosis that effects skin and subcutaneous tissue located in foot, located in trunk, located in buttocks, located in eyelids, located in lacrimal glands, located in paranasal sinuses, located in mandible, located in scalp, located in neck, located in perineum, or located in testes and has symptom sinus discharge and results in formation of nodules.", "url": "https://disease-ontology.org/term/DOID:13078", "evidence": [ { "id": "13078", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13078" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1561", "name": "cognitive disorder", "description": "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.", "url": "https://disease-ontology.org/term/DOID:1561", "evidence": [ { "id": "1561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1561" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1849", "name": "cannabis dependence", "description": "A drug dependence that involves the continued use of cannabis despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:1849", "evidence": [ { "id": "1849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1849" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:2560", "name": "morphine dependence", "description": "An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2560", "evidence": [ { "id": "2560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2560" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4676", "name": "uremia", "description": "", "url": "https://disease-ontology.org/term/DOID:4676", "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:631", "name": "fibromyalgia", "description": "A syndrome that is is characterized by chronic widespread musculoskeletal pain, fatigue, sleep disturbances, cognitive dysfunction and depression.", "url": "https://disease-ontology.org/term/DOID:631", "evidence": [ { "id": "631", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:631" } ], "weight": 0.0 }, { "disease_id": "DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:670", "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:9505", "name": "cannabis abuse", "description": "A substance abuse that involves the recurring use of cannabis despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:9505", "evidence": [ { "id": "9505", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9505" } ], "weight": 0.0 }, { "disease_id": "DOID:9828", "name": "neonatal abstinence syndrome", "description": "A withdrawal disorder that is characterized by a group of problems that occur in a newborn who was exposed to addictive illegal or prescription drugs while in the mother's womb or postnatally following the discontinuance of drug treatment.", "url": "https://disease-ontology.org/term/DOID:9828", "evidence": [ { "id": "9828", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9828" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9974", "name": "drug dependence", "description": "A substance dependence that involves the continued use of drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9974", "evidence": [ { "id": "9974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9974" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "F4ZGF2", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2" } ], "pmid": "" }, { "name": "catechol O-methyltransferase activity", "id": "GO:0016206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016206", "evidence": [ { "database": "UniProtKB", "id": "F4ZGF2", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F4ZGF2", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2" } ], "pmid": "" } ], "biological_process": [ { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "F4ZGF2", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2" } ], "pmid": "" }, { "name": "dopamine metabolic process", "id": "GO:0042417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042417", "evidence": [ { "database": "UniProtKB", "id": "F4ZGF2", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F4ZGF2", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2" } ], "pmid": "" }, { "name": "catecholamine catabolic process", "id": "GO:0042424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042424", "evidence": [ { "database": "UniProtKB", "id": "F4ZGF2", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F4ZGF2-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Asn58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 58, "start_aa": "Asn", "end_pos": 58, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn58", "evidence": [ { "id": "F4ZGF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F4ZGF2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F6P2X6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F6P2X6", "url": "https://www.uniprot.org/uniprotkb/F6P2X6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 362, "chemical_mass": 41046.0, "gene_names": "gjd6;cx35.8;cx36.7;ecx;ftk;gjd6;zfcx41.04", "protein_name": "Gap junction protein", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6P2X6", "url": "https://www.uniprot.org/uniprotkb/F6P2X6" } ], "pmid": "" }, { "name": "connexin complex", "id": "GO:0005922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", "evidence": [ { "database": "UniProtKB", "id": "F6P2X6", "url": "https://www.uniprot.org/uniprotkb/F6P2X6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "F6P2X6", "url": "https://www.uniprot.org/uniprotkb/F6P2X6" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "F6P2X6", "url": "https://www.uniprot.org/uniprotkb/F6P2X6" } ], "pmid": "" }, { "name": "cardiac myofibril assembly", "id": "GO:0055003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055003", "evidence": [ { "database": "UniProtKB", "id": "F6P2X6", "url": "https://www.uniprot.org/uniprotkb/F6P2X6" } ], "pmid": "" } ], "molecular_function": [ { "name": "gap junction hemi-channel activity", "id": "GO:0055077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055077", "evidence": [ { "database": "UniProtKB", "id": "F6P2X6", "url": "https://www.uniprot.org/uniprotkb/F6P2X6" } ], "pmid": "" }, { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "F6P2X6", "url": "https://www.uniprot.org/uniprotkb/F6P2X6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F6P7Z9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 770, "chemical_mass": 88450.0, "gene_names": "cpt1b;cpt1al;cpt1b;zgc:103709", "protein_name": "Carnitine O-palmitoyltransferase 1, muscle isoform", "disease": [], "molecular_function": [ { "name": "carnitine O-palmitoyltransferase activity", "id": "GO:0004095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004095", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" }, { "name": "long-chain fatty acid transport", "id": "GO:0015909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015909", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" }, { "name": "carnitine metabolic process", "id": "GO:0009437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009437", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" }, { "name": "response to (R)-carnitine", "id": "GO:0061959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061959", "evidence": [ { "database": "UniProtKB", "id": "F6P7Z9", "url": "https://www.uniprot.org/uniprotkb/F6P7Z9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F6P8Y7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2543, "chemical_mass": 275454.0, "gene_names": "stab2;si:dkey-207j16.6;stab2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "blood vessel development", "id": "GO:0001568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001568", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "low-density lipoprotein particle clearance", "id": "GO:0034383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034383", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis involved in cholesterol transport", "id": "GO:0090118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090118", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "blood vessel endothelial cell differentiation", "id": "GO:0060837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060837", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "positive regulation of lymphangiogenesis", "id": "GO:1901492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901492", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" }, { "name": "oxidised low-density lipoprotein particle clearance", "id": "GO:0150024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150024", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6P8Y7", "url": "https://www.uniprot.org/uniprotkb/F6P8Y7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "F6P8Y7-1", "start_pos": "2445", "end_pos": "2445", "site_lbl": "Thr2445", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2445, "start_aa": "Thr", "end_pos": 2445, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2445", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "F6P8Y7-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Thr74", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 74, "start_aa": "Thr", "end_pos": 74, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr74", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "F8W3D2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 496, "chemical_mass": 55758.0, "gene_names": "pparda;pparda", "protein_name": "", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:4607", "name": "biliary tract cancer", "description": "A hepatobiliary system cancer that results_in malignant growth located_in the gallbladder or located_in the bile duct.", "url": "https://disease-ontology.org/term/DOID:4607", "evidence": [ { "id": "4607", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4607" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "negative regulation of cholesterol storage", "id": "GO:0010887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010887", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "neural crest cell development", "id": "GO:0014032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014032", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "response to activity", "id": "GO:0014823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014823", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "intracellular receptor signaling pathway", "id": "GO:0030522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030522", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "positive regulation of fatty acid metabolic process", "id": "GO:0045923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045923", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "regulation of skeletal muscle satellite cell proliferation", "id": "GO:0014842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014842", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "F8W3D2", "url": "https://www.uniprot.org/uniprotkb/F8W3D2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "H6D7E6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "H6D7E6", "url": "https://www.uniprot.org/uniprotkb/H6D7E6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1554, "chemical_mass": 167601.0, "gene_names": "talpid3", "protein_name": "Protein TALPID3", "disease": [], "cellular_component": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "H6D7E6", "url": "https://www.uniprot.org/uniprotkb/H6D7E6" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "H6D7E6", "url": "https://www.uniprot.org/uniprotkb/H6D7E6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "H6D7E6", "url": "https://www.uniprot.org/uniprotkb/H6D7E6" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "H6D7E6", "url": "https://www.uniprot.org/uniprotkb/H6D7E6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "H6D7E6-1", "start_pos": "1099", "end_pos": "1099", "site_lbl": "Thr1099", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1099, "start_aa": "Thr", "end_pos": 1099, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1099", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "H6D7E6-1", "start_pos": "1103", "end_pos": "1103", "site_lbl": "Thr1103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1103, "start_aa": "Thr", "end_pos": 1103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1103", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "H6D7E6-1", "start_pos": "1168", "end_pos": "1168", "site_lbl": "Thr1168", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1168, "start_aa": "Thr", "end_pos": 1168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1168", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "H6D7E6-1", "start_pos": "892", "end_pos": "892", "site_lbl": "Thr892", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 892, "start_aa": "Thr", "end_pos": 892, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr892", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "H6D7E6-1", "start_pos": "970", "end_pos": "970", "site_lbl": "Thr970", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 970, "start_aa": "Thr", "end_pos": 970, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr970", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "H9BFW7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "H9BFW7", "url": "https://www.uniprot.org/uniprotkb/H9BFW7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 423, "chemical_mass": 47665.0, "gene_names": "cmasb;cmas2;cmasb", "protein_name": "N-acylneuraminate cytidylyltransferase B", "disease": [ { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 } ], "biological_process": [ { "name": "N-acetylneuraminate metabolic process", "id": "GO:0006054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006054", "evidence": [ { "database": "UniProtKB", "id": "H9BFW7", "url": "https://www.uniprot.org/uniprotkb/H9BFW7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "H9BFW7", "url": "https://www.uniprot.org/uniprotkb/H9BFW7" } ], "pmid": "" } ], "molecular_function": [ { "name": "N-acylneuraminate cytidylyltransferase activity", "id": "GO:0008781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008781", "evidence": [ { "database": "UniProtKB", "id": "H9BFW7", "url": "https://www.uniprot.org/uniprotkb/H9BFW7" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "H9BFW7", "url": "https://www.uniprot.org/uniprotkb/H9BFW7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O42115-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 453, "chemical_mass": 49396.0, "gene_names": "arxa;arxa;arx;phox2a", "protein_name": "Aristaless-related homeobox protein A", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0050709", "name": "early infantile epileptic encephalopathy", "description": "A neonatal period electroclinical syndrome that is characterized by tonic spasms and partial seizures.", "url": "https://disease-ontology.org/term/DOID:0050709", "evidence": [ { "id": "0050709", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050709" } ], "weight": 0.0 }, { "disease_id": "DOID:0050776", "name": "non-syndromic X-linked intellectual disability", "description": "A non-syndromic intellectual disability characterized by a X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0050776", "evidence": [ { "id": "0050776", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050776" } ], "weight": 0.0 }, { "disease_id": "DOID:0060309", "name": "syndromic X-linked intellectual disability", "description": "A syndromic intellectual disability characterized by an X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060309", "evidence": [ { "id": "0060309", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060309" } ], "weight": 0.0 }, { "disease_id": "DOID:0060806", "name": "syndromic X-linked intellectual disability Hedera type", "description": "A syndromic X-linked intellectual disability characterized by mild to moderate mental retardation and epilepsy that has_material_basis_in mutation in the ATP6AP2 gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060806", "evidence": [ { "id": "0060806", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060806" } ], "weight": 0.0 }, { "disease_id": "DOID:0080468", "name": "developmental and epileptic encephalopathy 1", "description": "A developmental and epileptic encephalopathy characterized by X-linked recessive inheritance of frequent tonic seizures or spasms beginning in infancy that has_material_basis_in mutation in the ARX gene on chromosome Xp21.", "url": "https://disease-ontology.org/term/DOID:0080468", "evidence": [ { "id": "0080468", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080468" } ], "weight": 0.0 }, { "disease_id": "DOID:0112021", "name": "non-syndromic X-linked intellectual disability ARX-related", "description": "A non-syndromic X-linked intellectual disability characterized by moderate to profound intellectual disability with variable additional features that has_material_basis_in hemizygous mutation in ARX on chromosome Xp21.3.", "url": "https://disease-ontology.org/term/DOID:0112021", "evidence": [ { "id": "0112021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112021" } ], "weight": 0.0 }, { "disease_id": "DOID:0112038", "name": "non-syndromic X-linked intellectual disability 1", "description": "A non-syndromic X-linked intellectual disability characterized by moderate to severe intellectual disability in males and varying levels of intellectual disability in females that has_material_basis_in hemizygous or heterozygous mutation in the IQSEC2 gene on chromosome Xp11.22.", "url": "https://disease-ontology.org/term/DOID:0112038", "evidence": [ { "id": "0112038", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112038" } ], "weight": 0.0 }, { "disease_id": "DOID:0112151", "name": "corpus callosum agenesis-abnormal genitalia syndrome", "description": "A syndrome characterized by agenesis of the corpus callosum, severe intellectual disability, seizures, and spasticity with males showing a severe phenotype and females showing a mild or non-affected phenotype that has_material_basis_in mutation in ARX on chromosome Xp21.3.", "url": "https://disease-ontology.org/term/DOID:0112151", "evidence": [ { "id": "0112151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112151" } ], "weight": 0.0 }, { "disease_id": "DOID:0112238", "name": "X-linked lissencephaly 2", "description": "A lissencephaly characterized by structural brain anomalies, early-onset intractable seizures, severe psychomotor retardation, and ambiguous genitalia that has_material_basis_in mutation in ARX on chromosome Xp21.3.", "url": "https://disease-ontology.org/term/DOID:0112238", "evidence": [ { "id": "0112238", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112238" } ], "weight": 0.0 }, { "disease_id": "DOID:14744", "name": "Partington syndrome", "description": "A syndrome characterized by intellectual disability, focal dystonia of the hands and dysarthria.", "url": "https://disease-ontology.org/term/DOID:14744", "evidence": [ { "id": "14744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14744" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "pancreatic A cell development", "id": "GO:0003322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003322", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" }, { "name": "subthalamus development", "id": "GO:0021539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021539", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" }, { "name": "telencephalon development", "id": "GO:0021537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021537", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" }, { "name": "thalamus development", "id": "GO:0021794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021794", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" }, { "name": "pancreatic A cell differentiation", "id": "GO:0003310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003310", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "O42115", "url": "https://www.uniprot.org/uniprotkb/O42115" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O42366-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 311, "chemical_mass": 34199.0, "gene_names": "hoxb1a;hoxb1", "protein_name": "Homeobox protein Hox-B1a", "disease": [], "biological_process": [ { "name": "rhombomere 4 development", "id": "GO:0021570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021570", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "facial nucleus development", "id": "GO:0021754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021754", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "cell migration in hindbrain", "id": "GO:0021535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021535", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "facial nerve development", "id": "GO:0021561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021561", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "rhombomere 4 morphogenesis", "id": "GO:0021661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021661", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "hindbrain maturation", "id": "GO:0021578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021578", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "O42366", "url": "https://www.uniprot.org/uniprotkb/O42366" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O42376-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 363, "chemical_mass": 41971.0, "gene_names": "mapk12a;mapk12;erk6;etID309866.18;fa05c12;mapk12;sapk3;wu:fa05c12;zgc:101695", "protein_name": "Mitogen-activated protein kinase 12", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" }, { "name": "MAP kinase activity", "id": "GO:0004707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004707", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O42376-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Thr181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ] } ] }, { "uniprot_canonical_ac": "O42376-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Tyr183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "O42376", "url": "https://www.uniprot.org/uniprotkb/O42376" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O57374-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 236, "chemical_mass": 27132.0, "gene_names": "hoxd4a;hoxd4", "protein_name": "Homeobox protein Hox-D4a", "disease": [ { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 } ], "biological_process": [ { "name": "hemangioblast cell differentiation", "id": "GO:0060217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060217", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "vasculogenesis", "id": "GO:0001570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001570", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "embryonic skeletal system morphogenesis", "id": "GO:0048704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "primitive hemopoiesis", "id": "GO:0060215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060215", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "O57374", "url": "https://www.uniprot.org/uniprotkb/O57374" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O57409-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 615, "chemical_mass": 67593.0, "gene_names": "dlb;dlb;etID309872.5;sc:d0400", "protein_name": "Delta-like protein B", "disease": [ { "disease_id": "DOID:0050568", "name": "spondylocostal dysostosis", "description": "A dysostosis that results_in abnormal development located_in vertebrae or located_in ribs. The bones of the spine do not develop properly, which causes them to be misshapen and abnormally joined together.", "url": "https://disease-ontology.org/term/DOID:0050568", "evidence": [ { "id": "0050568", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050568" } ], "weight": 0.0 }, { "disease_id": "DOID:0112365", "name": "spondylocostal dysostosis 1", "description": "A spondylocostal dysostosis that has_material_basis_in homozygous or compound heterozygous mutation in the DLL3 gene on chromosome 19q13.2.", "url": "https://disease-ontology.org/term/DOID:0112365", "evidence": [ { "id": "0112365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112365" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1934", "name": "dysostosis", "description": "A bone development disease that results in defective ossification of bone.", "url": "https://disease-ontology.org/term/DOID:1934", "evidence": [ { "id": "1934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1934" } ], "weight": 0.0 } ], "biological_process": [ { "name": "diencephalon development", "id": "GO:0021536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021536", "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "pmid": "" }, { "name": "midbrain development", "id": "GO:0030901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030901", "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "O57409", "url": "https://www.uniprot.org/uniprotkb/O57409" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O57409-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Asn459", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 459, "start_aa": "Asn", "end_pos": 459, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn459", "evidence": [ { "id": "O57409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O57409#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O73727-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 108, "chemical_mass": 11904.0, "gene_names": "ins;ins;zgc:109842", "protein_name": "Insulin", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 }, { "disease_id": "DOID:0050524", "name": "maturity-onset diabetes of the young", "description": "A diabetes mellitus that has_material_basis_in autosomal dominant inheritance of mutations in the MODY genes impacting beta-cell function, typically occurring before 25 years of age and caused by primary insulin secretion defects.", "url": "https://disease-ontology.org/term/DOID:0050524", "evidence": [ { "id": "0050524", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050524" } ], "weight": 0.0 }, { "disease_id": "DOID:0060639", "name": "permanent neonatal diabetes mellitus", "description": "A neonatal diabetes that has_material_basis_in homozygous mutation in the glucokinase gene (GCK), heterozygous mutation in the KCNJ11 and INS genes, or by heterozygous or homozygous mutation in the ABCC8 gene.", "url": "https://disease-ontology.org/term/DOID:0060639", "evidence": [ { "id": "0060639", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060639" } ], "weight": 0.0 }, { "disease_id": "DOID:0110741", "name": "type 1 diabetes mellitus 2", "description": "A type 1 diabetes mellitus that has_material_basis_in autosomal dominant inheritance of mutation of the INS gene on chromosome 11p15.5.", "url": "https://disease-ontology.org/term/DOID:0110741", "evidence": [ { "id": "0110741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110741" } ], "weight": 0.0 }, { "disease_id": "DOID:0111108", "name": "maturity-onset diabetes of the young type 10", "description": "A maturity-onset diabetes of the young that has_material_basis_in heterozygous mutation in the INS gene on chromosome 11p15.5.", "url": "https://disease-ontology.org/term/DOID:0111108", "evidence": [ { "id": "0111108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111108" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy.", "url": "https://disease-ontology.org/term/DOID:11714", "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ], "weight": 0.0 }, { "disease_id": "DOID:11717", "name": "neonatal diabetes mellitus", "description": "A diabetes mellitus that is characterized by hyperglycemia occurring within the first 6 months of life.", "url": "https://disease-ontology.org/term/DOID:11717", "evidence": [ { "id": "11717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11717" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1920", "name": "hyperuricemia", "description": "An acquired metabolic disease that has_material_basis_in an abnormally high level of uric acid in the blood.", "url": "https://disease-ontology.org/term/DOID:1920", "evidence": [ { "id": "1920", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1920" } ], "weight": 0.0 }, { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:3892", "name": "insulinoma", "description": "A pancreatic cystadenoma that is characterized by the overproduction of insulin.", "url": "https://disease-ontology.org/term/DOID:3892", "evidence": [ { "id": "3892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3892" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:535", "name": "sleep disorder", "description": "A disease of mental health that involves disruption of sleep patterns.", "url": "https://disease-ontology.org/term/DOID:535", "evidence": [ { "id": "535", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:535" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of feeding behavior", "id": "GO:2000252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000252", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" }, { "name": "response to nutrient levels", "id": "GO:0031667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031667", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" }, { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" }, { "name": "response to glucose", "id": "GO:0009749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009749", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" }, { "name": "type B pancreatic cell differentiation", "id": "GO:0003309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003309", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" }, { "name": "positive regulation of pancreatic A cell differentiation", "id": "GO:2000228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000228", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" } ], "molecular_function": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "O73727", "url": "https://www.uniprot.org/uniprotkb/O73727" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "O73797-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 233, "chemical_mass": 26423.0, "gene_names": "ntf7;NT-7;ngfa;nt7;ntf6/7;ntf7;zNT-7;znt7", "protein_name": "Neurotrophin-7", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:0051061", "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ], "weight": 0.0 }, { "disease_id": "DOID:0051065", "name": "chronic pancreatitis", "description": "A pancreatitis that is characterized by long-term inflamation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:0051065", "evidence": [ { "id": "0051065", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051065" } ], "weight": 0.0 }, { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:0070145", "name": "hereditary sensory and autonomic neuropathy type 5", "description": "A hereditary sensory and autonomic neuropathy characterized by impaired pain and thermal perception in the extremities and selective reduction in small myelinated fibers that has_material_basis_in homozygous mutation in the NGF gene on chromosome 1p13.", "url": "https://disease-ontology.org/term/DOID:0070145", "evidence": [ { "id": "0070145", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070145" } ], "weight": 0.0 }, { "disease_id": "DOID:0070355", "name": "overactive bladder syndrome", "description": "A bladder disease characterized by urinary urgency without urinary tract infection or obvious pathology, usually accompanied by urinary frequency and nocturia.", "url": "https://disease-ontology.org/term/DOID:0070355", "evidence": [ { "id": "0070355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070355" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080809", "name": "chronic asthma", "description": "An asthma that is characterized by the development of persistent airway inflammation and recurrent attacks of breathlessness and wheezing, which vary in severity and frequency.", "url": "https://disease-ontology.org/term/DOID:0080809", "evidence": [ { "id": "0080809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080809" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:0081292", "name": "traumatic brain injury", "description": "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.", "url": "https://disease-ontology.org/term/DOID:0081292", "evidence": [ { "id": "0081292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081292" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10685", "name": "separation anxiety disorder", "description": "An anxiety disorder that involves the feeling of excessive and inappropriate levels of anxiety over being separated from a person to whom the individual has a strong emotional attachment or place.", "url": "https://disease-ontology.org/term/DOID:10685", "evidence": [ { "id": "10685", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10685" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11383", "name": "cryptorchidism", "description": "", "url": "https://disease-ontology.org/term/DOID:11383", "evidence": [ { "id": "11383", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11383" } ], "weight": 0.0 }, { "disease_id": "DOID:12143", "name": "neurogenic bladder", "description": "", "url": "https://disease-ontology.org/term/DOID:12143", "evidence": [ { "id": "12143", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12143" } ], "weight": 0.0 }, { "disease_id": "DOID:1273", "name": "respiratory syncytial virus infectious disease", "description": "A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus (Orthopneumovirus hominis), which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress.", "url": "https://disease-ontology.org/term/DOID:1273", "evidence": [ { "id": "1273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1273" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:13948", "name": "bladder neck obstruction", "description": "", "url": "https://disease-ontology.org/term/DOID:13948", "evidence": [ { "id": "13948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13948" } ], "weight": 0.0 }, { "disease_id": "DOID:13949", "name": "interstitial cystitis", "description": "", "url": "https://disease-ontology.org/term/DOID:13949", "evidence": [ { "id": "13949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13949" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1679", "name": "cystitis", "description": "A bladder disease that is characterized by inflammation of the bladder.", "url": "https://disease-ontology.org/term/DOID:1679", "evidence": [ { "id": "1679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1679" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:2560", "name": "morphine dependence", "description": "An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2560", "evidence": [ { "id": "2560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2560" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3310", "name": "atopic dermatitis", "description": "An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.", "url": "https://disease-ontology.org/term/DOID:3310", "evidence": [ { "id": "3310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3310" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:431", "name": "myofascial pain syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:431", "evidence": [ { "id": "431", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:431" } ], "weight": 0.0 }, { "disease_id": "DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.", "url": "https://disease-ontology.org/term/DOID:4483", "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ], "weight": 0.0 }, { "disease_id": "DOID:5154", "name": "borna disease", "description": "A viral infectious disease that results_in infection, which affects dopaminergic neurotransmission located_in central nervous system, has_material_basis_in Borna disease virus (Orthobornavirus bornaense), which is transmitted_by contact with infected oronasal secretions. The infection has_symptom mood disturbances, has_symptom behaviour disturbances, has_symptom cognitive disturbances, has_symptom neurologic disturbances, and has_symptom movement impairment.", "url": "https://disease-ontology.org/term/DOID:5154", "evidence": [ { "id": "5154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5154" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:90", "name": "degenerative disc disease", "description": "A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc.", "url": "https://disease-ontology.org/term/DOID:90", "evidence": [ { "id": "90", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:90" } ], "weight": 0.0 }, { "disease_id": "DOID:9279", "name": "hyperhomocysteinemia", "description": "An amino acid metabolic disorder that involves an abnormally large level of homocysteine in the blood.", "url": "https://disease-ontology.org/term/DOID:9279", "evidence": [ { "id": "9279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9279" } ], "weight": 0.0 }, { "disease_id": "DOID:9470", "name": "bacterial meningitis", "description": "A meningitis that has_material_basis_in a bacterial infection.", "url": "https://disease-ontology.org/term/DOID:9470", "evidence": [ { "id": "9470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9470" } ], "weight": 0.0 }, { "disease_id": "DOID:9505", "name": "cannabis abuse", "description": "A substance abuse that involves the recurring use of cannabis despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:9505", "evidence": [ { "id": "9505", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9505" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" }, { "name": "nerve development", "id": "GO:0021675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021675", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" }, { "name": "nerve growth factor signaling pathway", "id": "GO:0038180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038180", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" } ], "molecular_function": [ { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" }, { "name": "nerve growth factor receptor binding", "id": "GO:0005163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005163", "evidence": [ { "database": "UniProtKB", "id": "O73797", "url": "https://www.uniprot.org/uniprotkb/O73797" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P09013-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 276, "chemical_mass": 30912.0, "gene_names": "hoxb5b;ZF-54;ZF54;hoxa5;hoxb5-like;hoxb5b;hoxzf54;id:ibd2566;z-2;zf54;zgc:101134", "protein_name": "Homeobox protein Hox-B5b", "disease": [], "biological_process": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" }, { "name": "cardioblast differentiation", "id": "GO:0010002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010002", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P09013", "url": "https://www.uniprot.org/uniprotkb/P09013" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P09014-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 275, "chemical_mass": 30558.0, "gene_names": "hoxb5a;ZF-21;ZF21;hox-2.1;hox-B5;hox-b5;hoxb5a;hoxb5;wu:fc38c09;z-18;zf21", "protein_name": "Homeobox protein Hox-B5a", "disease": [], "biological_process": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P09014", "url": "https://www.uniprot.org/uniprotkb/P09014" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P0C218-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 761, "chemical_mass": 85002.0, "gene_names": "ddx20;fb59a11;gemin3;si:dkey-193l3.3;si:dkey-193l3.4;wu:fb16g08;wu:fb59a11", "protein_name": "Probable ATP-dependent RNA helicase DDX20", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" }, { "name": "SMN complex", "id": "GO:0032797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032797", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" }, { "name": "SMN-Sm protein complex", "id": "GO:0034719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034719", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" } ], "biological_process": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "P0C218", "url": "https://www.uniprot.org/uniprotkb/P0C218" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P0C7U5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 346, "chemical_mass": 39115.0, "gene_names": "c5ar1;C5a-R;C5aR;c5ar1", "protein_name": "C5a anaphylatoxin chemotactic receptor 1", "disease": [ { "disease_id": "DOID:0060903", "name": "thrombosis", "description": "A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.", "url": "https://disease-ontology.org/term/DOID:0060903", "evidence": [ { "id": "0060903", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060903" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:1227", "name": "neutropenia", "description": "", "url": "https://disease-ontology.org/term/DOID:1227", "evidence": [ { "id": "1227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1227" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.", "url": "https://disease-ontology.org/term/DOID:4483", "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "complement receptor mediated signaling pathway", "id": "GO:0002430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002430", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell proliferation", "id": "GO:0050679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050679", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "mRNA transcription by RNA polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" } ], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "complement component C5a receptor activity", "id": "GO:0004878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004878", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P0C7U5", "url": "https://www.uniprot.org/uniprotkb/P0C7U5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P0C7U5-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Asn15", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 15, "start_aa": "Asn", "end_pos": 15, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn15", "evidence": [ { "id": "P0C7U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C7U5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P0C7U5-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Asn4", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 4, "start_aa": "Asn", "end_pos": 4, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn4", "evidence": [ { "id": "P0C7U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C7U5#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P0CAT2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P0CAT2", "url": "https://www.uniprot.org/uniprotkb/P0CAT2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 287, "chemical_mass": 30986.0, "gene_names": "slc25a38b;SLC25A38;slc25a38b", "protein_name": "Mitochondrial glycine transporter B", "disease": [ { "disease_id": "DOID:0060065", "name": "autosomal recessive pyridoxine-refractory sideroblastic anemia 2", "description": "A sideroblastic anemia that is characterized by microcytic hypochromic anemia and iron overload, and has_material_basis_in autosomal recessive inheritance of mutation in the SLC25A38 gene.", "url": "https://disease-ontology.org/term/DOID:0060065", "evidence": [ { "id": "0060065", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060065" } ], "weight": 0.0 }, { "disease_id": "DOID:8955", "name": "sideroblastic anemia", "description": "A microcytic anemia where the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes).", "url": "https://disease-ontology.org/term/DOID:8955", "evidence": [ { "id": "8955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8955" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "glycine transmembrane transporter activity", "id": "GO:0015187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015187", "evidence": [ { "database": "UniProtKB", "id": "P0CAT2", "url": "https://www.uniprot.org/uniprotkb/P0CAT2" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P0CAT2", "url": "https://www.uniprot.org/uniprotkb/P0CAT2" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "P0CAT2", "url": "https://www.uniprot.org/uniprotkb/P0CAT2" } ], "pmid": "" } ], "biological_process": [ { "name": "hemoglobin metabolic process", "id": "GO:0020027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020027", "evidence": [ { "database": "UniProtKB", "id": "P0CAT2", "url": "https://www.uniprot.org/uniprotkb/P0CAT2" } ], "pmid": "" }, { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "P0CAT2", "url": "https://www.uniprot.org/uniprotkb/P0CAT2" } ], "pmid": "" }, { "name": "hemoglobin biosynthetic process", "id": "GO:0042541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042541", "evidence": [ { "database": "UniProtKB", "id": "P0CAT2", "url": "https://www.uniprot.org/uniprotkb/P0CAT2" } ], "pmid": "" }, { "name": "glycine import into mitochondrion", "id": "GO:1904983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904983", "evidence": [ { "database": "UniProtKB", "id": "P0CAT2", "url": "https://www.uniprot.org/uniprotkb/P0CAT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P0CB65-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 574, "chemical_mass": 65522.0, "gene_names": "srrm4;ZnSR100;im:7136231;nSR100;si:dkey-1k23.1", "protein_name": "Serine/arginine repetitive matrix protein 4", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" }, { "name": "neuron maturation", "id": "GO:0042551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042551", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "P0CB65", "url": "https://www.uniprot.org/uniprotkb/P0CB65" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P0CF95-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 569, "chemical_mass": 65461.0, "gene_names": "bicdl1;bicdr1;ccdc64", "protein_name": "BICD family-like cargo adapter 1", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" }, { "name": "embryonic camera-type eye development", "id": "GO:0031076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031076", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" }, { "name": "vesicle transport along microtubule", "id": "GO:0047496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047496", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" }, { "name": "Golgi to secretory granule transport", "id": "GO:0055107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055107", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" }, { "name": "dynactin binding", "id": "GO:0034452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034452", "evidence": [ { "database": "UniProtKB", "id": "P0CF95", "url": "https://www.uniprot.org/uniprotkb/P0CF95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P0DX17-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P0DX17", "url": "https://www.uniprot.org/uniprotkb/P0DX17" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 555, "chemical_mass": 60009.0, "gene_names": "slc39a5;zip5", "protein_name": "Zinc transporter ZIP5", "disease": [], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "P0DX17", "url": "https://www.uniprot.org/uniprotkb/P0DX17" } ], "pmid": "" }, { "name": "monoatomic cation:bicarbonate symporter activity", "id": "GO:0140410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140410", "evidence": [ { "database": "UniProtKB", "id": "P0DX17", "url": "https://www.uniprot.org/uniprotkb/P0DX17" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P0DX17", "url": "https://www.uniprot.org/uniprotkb/P0DX17" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "P0DX17", "url": "https://www.uniprot.org/uniprotkb/P0DX17" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular monoatomic cation homeostasis", "id": "GO:0030003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030003", "evidence": [ { "database": "UniProtKB", "id": "P0DX17", "url": "https://www.uniprot.org/uniprotkb/P0DX17" } ], "pmid": "" }, { "name": "zinc ion import across plasma membrane", "id": "GO:0071578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071578", "evidence": [ { "database": "UniProtKB", "id": "P0DX17", "url": "https://www.uniprot.org/uniprotkb/P0DX17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P22574-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P22574", "url": "https://www.uniprot.org/uniprotkb/P22574" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 246, "chemical_mass": 27704.0, "gene_names": "hoxb4a;HOX-B4;Z-17;ZF-13;hox-b4;hoxb4a;hoxb4;sb:eu512;zf13", "protein_name": "Homeobox protein Hox-B4a", "disease": [ { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P22574", "url": "https://www.uniprot.org/uniprotkb/P22574" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P22574", "url": "https://www.uniprot.org/uniprotkb/P22574" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P22574", "url": "https://www.uniprot.org/uniprotkb/P22574" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "P22574", "url": "https://www.uniprot.org/uniprotkb/P22574" } ], "pmid": "" }, { "name": "embryonic skeletal system morphogenesis", "id": "GO:0048704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048704", "evidence": [ { "database": "UniProtKB", "id": "P22574", "url": "https://www.uniprot.org/uniprotkb/P22574" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P22574", "url": "https://www.uniprot.org/uniprotkb/P22574" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P22574", "url": "https://www.uniprot.org/uniprotkb/P22574" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P22574-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P31533-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 261, "chemical_mass": 29485.0, "gene_names": "eng2b;ENG-3;ZF-EN-1;en2b;en3;eng-3;eng2b;eng3;zf-en-1", "protein_name": "Homeobox protein engrailed-2b", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" }, { "name": "midbrain-hindbrain boundary development", "id": "GO:0030917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030917", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" }, { "name": "midbrain development", "id": "GO:0030901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030901", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P31533", "url": "https://www.uniprot.org/uniprotkb/P31533" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P47792-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 297, "chemical_mass": 32785.0, "gene_names": "sox19a;cb799;fc66c01;si:ch211-137i24.8;sox19a;sox19;wu:fc66c01", "protein_name": "Transcription factor Sox-19a", "disease": [ { "disease_id": "DOID:10155", "name": "intestinal cancer", "description": "A gastrointestinal system cancer that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:10155", "evidence": [ { "id": "10155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10155" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47792-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Ser160", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47792", "url": "https://www.uniprot.org/uniprotkb/P47792" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "P47792", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P47792" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P47794-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 410, "chemical_mass": 46631.0, "gene_names": "ccne1;ccne1;ccne;cyce;fa18e07;wu:fa18e07", "protein_name": "G1/S-specific cyclin-E1", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3458", "name": "breast adenocarcinoma", "description": "A breast carcinoma that originates in the milk ducts and/or lobules (glandular tissue) of the breast.", "url": "https://disease-ontology.org/term/DOID:3458", "evidence": [ { "id": "3458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3458" } ], "weight": 0.0 }, { "disease_id": "DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver.", "url": "https://disease-ontology.org/term/DOID:3571", "evidence": [ { "id": "3571", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3571" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4001", "name": "ovarian carcinoma", "description": "An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:4001", "evidence": [ { "id": "4001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4001" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8991", "name": "cervix uteri carcinoma in situ", "description": "An uterus carcinoma in situ that is located_in the uterine cervix.", "url": "https://disease-ontology.org/term/DOID:8991", "evidence": [ { "id": "8991", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8991" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" }, { "name": "cyclin E1-CDK2 complex", "id": "GO:0097134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097134", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" }, { "name": "positive regulation of G1/S transition of mitotic cell cycle", "id": "GO:1900087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900087", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" } ], "molecular_function": [ { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P47794-1", "start_pos": "397", "end_pos": "397", "site_lbl": "Thr397", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P47794", "url": "https://www.uniprot.org/uniprotkb/P47794" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P52722-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P52722", "url": "https://www.uniprot.org/uniprotkb/P52722" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 60, "chemical_mass": 5960.0, "gene_names": "mt;mt1;mt", "protein_name": "Metallothionein-1", "disease": [], "biological_process": [ { "name": "response to zinc ion", "id": "GO:0010043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010043", "evidence": [ { "database": "UniProtKB", "id": "P52722", "url": "https://www.uniprot.org/uniprotkb/P52722" } ], "pmid": "" }, { "name": "positive regulation of vascular endothelial growth factor production", "id": "GO:0010575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010575", "evidence": [ { "database": "UniProtKB", "id": "P52722", "url": "https://www.uniprot.org/uniprotkb/P52722" } ], "pmid": "" }, { "name": "response to cadmium ion", "id": "GO:0046686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046686", "evidence": [ { "database": "UniProtKB", "id": "P52722", "url": "https://www.uniprot.org/uniprotkb/P52722" } ], "pmid": "" }, { "name": "positive regulation of cell migration involved in sprouting angiogenesis", "id": "GO:0090050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090050", "evidence": [ { "database": "UniProtKB", "id": "P52722", "url": "https://www.uniprot.org/uniprotkb/P52722" } ], "pmid": "" }, { "name": "response to copper ion", "id": "GO:0046688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046688", "evidence": [ { "database": "UniProtKB", "id": "P52722", "url": "https://www.uniprot.org/uniprotkb/P52722" } ], "pmid": "" }, { "name": "response to methylmercury", "id": "GO:0051597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051597", "evidence": [ { "database": "UniProtKB", "id": "P52722", "url": "https://www.uniprot.org/uniprotkb/P52722" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P52722", "url": "https://www.uniprot.org/uniprotkb/P52722" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P53407-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 358, "chemical_mass": 39848.0, "gene_names": "isl2b;ISL-3;isl-3;isl2b;isl3;islet 3;zfIsl-3;zgc:109840", "protein_name": "Insulin gene enhancer protein isl-2b", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" } ], "biological_process": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" }, { "name": "neuron fate specification", "id": "GO:0048665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048665", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" }, { "name": "secondary heart field specification", "id": "GO:0003139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003139", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" }, { "name": "exocrine pancreas development", "id": "GO:0031017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031017", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "P53407", "url": "https://www.uniprot.org/uniprotkb/P53407" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P53544-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 240, "chemical_mass": 26981.0, "gene_names": "gsc;ZGSC;gsc;ik:tdsubc_1c10;ik:tdsubc_2g4;ik:tdsubc_2h11;xx:tdsubc_1c10;xx:tdsubc_2g4;xx:tdsubc_2h11;zgc:101595", "protein_name": "Homeobox protein goosecoid", "disease": [], "biological_process": [ { "name": "regulation of epithelial to mesenchymal transition", "id": "GO:0010717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010717", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "otic vesicle development", "id": "GO:0071599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071599", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "anterior/posterior axis specification", "id": "GO:0009948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009948", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "dorsal/ventral axis specification", "id": "GO:0009950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009950", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "neural plate anterior/posterior regionalization", "id": "GO:0021999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021999", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "neuroblast delamination", "id": "GO:0060234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060234", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P53544", "url": "https://www.uniprot.org/uniprotkb/P53544" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P58781-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P58781", "url": "https://www.uniprot.org/uniprotkb/P58781" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 503, "chemical_mass": 57506.0, "gene_names": "ada2a;ada2a;cecr1a;cecr1;fj65e02;wu:fj65e02", "protein_name": "Adenosine deaminase 2-A", "disease": [ { "disease_id": "DOID:106", "name": "pleural tuberculosis", "description": "An extrapulmonary tuberculosis that results_in lymphocyte-predominant exudative pleural effusion, located_in pleura. This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac.", "url": "https://disease-ontology.org/term/DOID:106", "evidence": [ { "id": "106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:106" } ], "weight": 0.0 }, { "disease_id": "DOID:13096", "name": "Sneddon syndrome", "description": "An artery disease that is characterized by onset of livedo reticularis in the second decade and onset of cerebrovascular disease in early adulthood and that has_material_basis_in compound heterozygous mutation in the CECR1 gene (ADA2) on chromosome 22q11.", "url": "https://disease-ontology.org/term/DOID:13096", "evidence": [ { "id": "13096", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13096" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenosine deaminase activity", "id": "GO:0004000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004000", "evidence": [ { "database": "UniProtKB", "id": "P58781", "url": "https://www.uniprot.org/uniprotkb/P58781" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P58781", "url": "https://www.uniprot.org/uniprotkb/P58781" } ], "pmid": "" }, { "name": "adenosine receptor binding", "id": "GO:0031685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031685", "evidence": [ { "database": "UniProtKB", "id": "P58781", "url": "https://www.uniprot.org/uniprotkb/P58781" } ], "pmid": "" }, { "name": "proteoglycan binding", "id": "GO:0043394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043394", "evidence": [ { "database": "UniProtKB", "id": "P58781", "url": "https://www.uniprot.org/uniprotkb/P58781" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P58781", "url": "https://www.uniprot.org/uniprotkb/P58781" } ], "pmid": "" } ], "biological_process": [ { "name": "adenosine catabolic process", "id": "GO:0006154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006154", "evidence": [ { "database": "UniProtKB", "id": "P58781", "url": "https://www.uniprot.org/uniprotkb/P58781" } ], "pmid": "" }, { "name": "inosine biosynthetic process", "id": "GO:0046103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046103", "evidence": [ { "database": "UniProtKB", "id": "P58781", "url": "https://www.uniprot.org/uniprotkb/P58781" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P58781-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Asn120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 120, "start_aa": "Asn", "end_pos": 120, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn120", "evidence": [ { "id": "P58781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P58781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P58781-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Asn167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 167, "start_aa": "Asn", "end_pos": 167, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn167", "evidence": [ { "id": "P58781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P58781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P58781-1", "start_pos": "178", "end_pos": "178", "site_lbl": "Asn178", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 178, "start_aa": "Asn", "end_pos": 178, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn178", "evidence": [ { "id": "P58781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P58781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P58781-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Asn290", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 290, "start_aa": "Asn", "end_pos": 290, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn290", "evidence": [ { "id": "P58781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P58781#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "P58781-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Asn371", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 371, "start_aa": "Asn", "end_pos": 371, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn371", "evidence": [ { "id": "P58781", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P58781#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P59889-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P59889", "url": "https://www.uniprot.org/uniprotkb/P59889" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 302, "chemical_mass": 32822.0, "gene_names": "slc39a1;DrZIP1;cb629;sb:cb629;slc39a1;zgc:111852;zip1", "protein_name": "Zinc transporter ZIP1", "disease": [], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "P59889", "url": "https://www.uniprot.org/uniprotkb/P59889" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P59889", "url": "https://www.uniprot.org/uniprotkb/P59889" } ], "pmid": "" } ], "biological_process": [ { "name": "zinc ion transmembrane transport", "id": "GO:0071577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071577", "evidence": [ { "database": "UniProtKB", "id": "P59889", "url": "https://www.uniprot.org/uniprotkb/P59889" } ], "pmid": "" }, { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "P59889", "url": "https://www.uniprot.org/uniprotkb/P59889" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P59889", "url": "https://www.uniprot.org/uniprotkb/P59889" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P59889", "url": "https://www.uniprot.org/uniprotkb/P59889" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P60622-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 224, "chemical_mass": 23956.0, "gene_names": "zfpm1;fog1", "protein_name": "Zinc finger protein ZFPM1", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "P60622", "url": "https://www.uniprot.org/uniprotkb/P60622" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P62247-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 208, "chemical_mass": 24093.0, "gene_names": "rps8;mg:ab03d05;rps8a;rps8;wu:fa92d06;zgc:92679", "protein_name": "Small ribosomal subunit protein eS8", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "P62247", "url": "https://www.uniprot.org/uniprotkb/P62247" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P79733-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P79733", "url": "https://www.uniprot.org/uniprotkb/P79733" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 386, "chemical_mass": 44594.0, "gene_names": "rrm2l;rrm2;cb111;chunp6884;r2;rrm2l;rrm2;si:ch73-187m15.5", "protein_name": "Ribonucleoside-diphosphate reductase subunit M2", "disease": [ { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2870", "name": "endometrial adenocarcinoma", "description": "An endometrial carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2870", "evidence": [ { "id": "2870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2870" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P79733", "url": "https://www.uniprot.org/uniprotkb/P79733" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "P79733", "url": "https://www.uniprot.org/uniprotkb/P79733" } ], "pmid": "" }, { "name": "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor", "id": "GO:0004748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004748", "evidence": [ { "database": "UniProtKB", "id": "P79733", "url": "https://www.uniprot.org/uniprotkb/P79733" } ], "pmid": "" } ], "biological_process": [ { "name": "deoxyribonucleotide biosynthetic process", "id": "GO:0009263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009263", "evidence": [ { "database": "UniProtKB", "id": "P79733", "url": "https://www.uniprot.org/uniprotkb/P79733" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P79733-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Thr31", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P79733", "url": "https://www.uniprot.org/uniprotkb/P79733" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "P79733", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P79733" } ] } ] }, { "uniprot_canonical_ac": "P79733-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Ser6", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P79733", "url": "https://www.uniprot.org/uniprotkb/P79733" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "P79733", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P79733" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P79737-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P79737", "url": "https://www.uniprot.org/uniprotkb/P79737" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 188, "chemical_mass": 21339.0, "gene_names": "nras", "protein_name": "GTPase NRas", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0060581", "name": "Noonan syndrome 3", "description": "A Noonan syndrome that has_material_basis_in heterozygous mutation in the KRAS gene.", "url": "https://disease-ontology.org/term/DOID:0060581", "evidence": [ { "id": "0060581", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060581" } ], "weight": 0.0 }, { "disease_id": "DOID:0060584", "name": "Noonan syndrome 6", "description": "A Noonan syndrome that has_material_basis_in heterozygous mutation in the NRAS gene on chromosome 1p13.", "url": "https://disease-ontology.org/term/DOID:0060584", "evidence": [ { "id": "0060584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060584" } ], "weight": 0.0 }, { "disease_id": "DOID:0080690", "name": "RASopathy", "description": "A syndrome that has_material_basis_in mutations in genes that alter the Ras subfamily and mitogen-activated protein kinases that control signal transduction.", "url": "https://disease-ontology.org/term/DOID:0080690", "evidence": [ { "id": "0080690", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080690" } ], "weight": 0.0 }, { "disease_id": "DOID:0110117", "name": "autoimmune lymphoproliferative syndrome type 4", "description": "An autoimmune lymphoproliferative syndrome that has_material_basis_in somatic mutation in the NRAS gene or the KRAS gene on chromosome 12p12.", "url": "https://disease-ontology.org/term/DOID:0110117", "evidence": [ { "id": "0110117", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110117" } ], "weight": 0.0 }, { "disease_id": "DOID:0111162", "name": "epidermal nevus", "description": "A skin disease characterized by localized epidermal thickening with hyperpigmentation that develops at or shortly after birth.", "url": "https://disease-ontology.org/term/DOID:0111162", "evidence": [ { "id": "0111162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111162" } ], "weight": 0.0 }, { "disease_id": "DOID:0111359", "name": "large congenital melanocytic nevus", "description": "A skin disease characterized by the presence at birth of a pigmented skin lesion composed of melanocytes of more than 20 cm in projected adult diameter that has_material_basis_in somatic mutation in the NRAS gene on chromosome 11p15.5.", "url": "https://disease-ontology.org/term/DOID:0111359", "evidence": [ { "id": "0111359", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111359" } ], "weight": 0.0 }, { "disease_id": "DOID:0111530", "name": "linear nevus sebaceous syndrome", "description": "A syndrome characterized by sebaceous nevi typically on the face and associated with variable ipsilateral abnormalities of the central nervous system, ocular anomalies, and skeletal defects that has_material_basis_in somatic mosaic mutations in the NRAS, HRAS, or KRAS genes on chromosomes 1p13.2, 11p15.5, or 12p12.1, respectively.", "url": "https://disease-ontology.org/term/DOID:0111530", "evidence": [ { "id": "0111530", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111530" } ], "weight": 0.0 }, { "disease_id": "DOID:10155", "name": "intestinal cancer", "description": "A gastrointestinal system cancer that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:10155", "evidence": [ { "id": "10155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10155" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:263", "name": "kidney cancer", "description": "A urinary system cancer that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:263", "evidence": [ { "id": "263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:263" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:686", "name": "liver carcinoma", "description": "A liver cancer that has_material_basis_in epithelial cells.", "url": "https://disease-ontology.org/term/DOID:686", "evidence": [ { "id": "686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:686" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9446", "name": "cholangitis", "description": "A bile duct disease that is an inflammation of the bile duct.", "url": "https://disease-ontology.org/term/DOID:9446", "evidence": [ { "id": "9446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9446" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "P79737", "url": "https://www.uniprot.org/uniprotkb/P79737" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P79737", "url": "https://www.uniprot.org/uniprotkb/P79737" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "P79737", "url": "https://www.uniprot.org/uniprotkb/P79737" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "P79737", "url": "https://www.uniprot.org/uniprotkb/P79737" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "P79737", "url": "https://www.uniprot.org/uniprotkb/P79737" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "P79737", "url": "https://www.uniprot.org/uniprotkb/P79737" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "P79737", "url": "https://www.uniprot.org/uniprotkb/P79737" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P79741-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 583, "chemical_mass": 67898.0, "gene_names": "pes;pes;si:dkeyp-86g2.3", "protein_name": "Pescadillo", "disease": [ { "disease_id": "DOID:0060479", "name": "Shwachman-Diamond syndrome", "description": "A syndrome characterized by exocrine pancreatic insufficiency, bone marrow failure and skeletal abnormalities.", "url": "https://disease-ontology.org/term/DOID:0060479", "evidence": [ { "id": "0060479", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060479" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" }, { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" }, { "name": "PeBoW complex", "id": "GO:0070545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070545", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" }, { "name": "oligodendrocyte differentiation", "id": "GO:0048709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048709", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" }, { "name": "exocrine pancreas development", "id": "GO:0031017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031017", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000466", "evidence": [ { "database": "UniProtKB", "id": "P79741", "url": "https://www.uniprot.org/uniprotkb/P79741" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P79741-1", "start_pos": "508", "end_pos": "508", "site_lbl": "Thr508", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 508, "start_aa": "Thr", "end_pos": 508, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr508", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P79746-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 378, "chemical_mass": 41816.0, "gene_names": "pou3f2;pou3f2b;pou3f2;pou47;si:ch211-201n18.1;zp47pou;zp47", "protein_name": "POU domain, class 3, transcription factor 2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" } ], "pmid": "" }, { "name": "endothelial cell development", "id": "GO:0001885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001885", "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "P79746-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Ser279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "P79746", "url": "https://www.uniprot.org/uniprotkb/P79746" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "P79746", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P79746" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P83238-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 45, "chemical_mass": 4838.0, "gene_names": "bglap", "protein_name": "Osteocalcin", "disease": [], "molecular_function": [ { "name": "structural constituent of bone", "id": "GO:0008147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008147", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "hydroxyapatite binding", "id": "GO:0046848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046848", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cellular response to insulin stimulus", "id": "GO:1900076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900076", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "negative regulation of bone development", "id": "GO:1903011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903011", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "osteoblast differentiation", "id": "GO:0001649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001649", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "response to vitamin K", "id": "GO:0032571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032571", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "type B pancreatic cell proliferation", "id": "GO:0044342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044342", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "P83238", "url": "https://www.uniprot.org/uniprotkb/P83238" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "P86839-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1265, "chemical_mass": 143400.0, "gene_names": "nes;nes", "protein_name": "Nestin", "disease": [ { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2527", "name": "nephrosis", "description": "A proteinuria that is characterized by the leaking of blood protein into the urine, swelling or edema, and degenerative lesions without inflammation.", "url": "https://disease-ontology.org/term/DOID:2527", "evidence": [ { "id": "2527", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2527" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cranial nerve development", "id": "GO:0021545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021545", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" }, { "name": "embryonic camera-type eye development", "id": "GO:0031076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031076", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" }, { "name": "positive regulation of neural precursor cell proliferation", "id": "GO:2000179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000179", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" }, { "name": "positive regulation of intermediate filament depolymerization", "id": "GO:0030844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030844", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" } ], "cellular_component": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" } ], "molecular_function": [ { "name": "intermediate filament binding", "id": "GO:0019215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019215", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" }, { "name": "CCR5 chemokine receptor binding", "id": "GO:0031730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031730", "evidence": [ { "database": "UniProtKB", "id": "P86839", "url": "https://www.uniprot.org/uniprotkb/P86839" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q03356-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 257, "chemical_mass": 28756.0, "gene_names": "msxb;etID309829.1;msh-B;msh-b;mshB;msx1b;msxb;wu:fk04h02;zgc:110559", "protein_name": "Homeobox protein MSH-B", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" }, { "name": "embryonic morphogenesis", "id": "GO:0048598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048598", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" }, { "name": "regulation of neuron apoptotic process", "id": "GO:0043523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043523", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" }, { "name": "embryonic viscerocranium morphogenesis", "id": "GO:0048703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048703", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" }, { "name": "otic placode formation", "id": "GO:0043049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043049", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" }, { "name": "fin regeneration", "id": "GO:0031101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031101", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q03356", "url": "https://www.uniprot.org/uniprotkb/Q03356" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q03356-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Thr129", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 129, "start_aa": "Thr", "end_pos": 129, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr129", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q06726-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 403, "chemical_mass": 45081.0, "gene_names": "nr2f5;COUP;couptf;nr2f5;svp46", "protein_name": "Nuclear receptor subfamily 2 group F member 5", "disease": [ { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" }, { "name": "response to retinoic acid", "id": "GO:0032526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032526", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "Q06726", "url": "https://www.uniprot.org/uniprotkb/Q06726" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q06726-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Thr30", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q06726-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q06726-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Thr38", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q071E0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 344, "chemical_mass": 39155.0, "gene_names": "kmt5aa;kmt5aa;set8a;setd8a;setd8;wu:fj33f02;zgc:153719", "protein_name": "N-lysine methyltransferase KMT5A-A", "disease": [], "biological_process": [ { "name": "regulation of DNA damage response, signal transduction by p53 class mediator", "id": "GO:0043516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043516", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "histone H4K20 methyltransferase activity", "id": "GO:0042799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042799", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" }, { "name": "histone H4K20 monomethyltransferase activity", "id": "GO:0140944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140944", "evidence": [ { "database": "UniProtKB", "id": "Q071E0", "url": "https://www.uniprot.org/uniprotkb/Q071E0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08BH7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 194, "chemical_mass": 21891.0, "gene_names": "ube2t;fanct;ube2t;wu:fj86h11;zgc:153687", "protein_name": "Ubiquitin-conjugating enzyme E2 T", "disease": [ { "disease_id": "DOID:0111081", "name": "Fanconi anemia complementation group T", "description": "A Fanconi anemia that has_material_basis_in compound heterozygous mutation in the UBE2T gene on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0111081", "evidence": [ { "id": "0111081", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111081" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "Q08BH7", "url": "https://www.uniprot.org/uniprotkb/Q08BH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08BL3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08BL3", "url": "https://www.uniprot.org/uniprotkb/Q08BL3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 408, "chemical_mass": 46596.0, "gene_names": "c1galt1la;c1galt1a;c1galt1la;fi11c09;wu:fi11c09;zgc:153355", "protein_name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-A", "disease": [ { "disease_id": "DOID:0060050", "name": "autoimmune disease of blood", "description": "An autoimmune disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the blood.", "url": "https://disease-ontology.org/term/DOID:0060050", "evidence": [ { "id": "0060050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060050" } ], "weight": 0.0 } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q08BL3", "url": "https://www.uniprot.org/uniprotkb/Q08BL3" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "Q08BL3", "url": "https://www.uniprot.org/uniprotkb/Q08BL3" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q08BL3", "url": "https://www.uniprot.org/uniprotkb/Q08BL3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q08BL3", "url": "https://www.uniprot.org/uniprotkb/Q08BL3" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q08BL3", "url": "https://www.uniprot.org/uniprotkb/Q08BL3" } ], "pmid": "" }, { "name": "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity", "id": "GO:0016263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016263", "evidence": [ { "database": "UniProtKB", "id": "Q08BL3", "url": "https://www.uniprot.org/uniprotkb/Q08BL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08BL3-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Asn401", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 401, "start_aa": "Asn", "end_pos": 401, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn401", "evidence": [ { "id": "Q08BL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08BL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08BL3-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Asn56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 56, "start_aa": "Asn", "end_pos": 56, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn56", "evidence": [ { "id": "Q08BL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08BL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08BL3-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Asn59", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 59, "start_aa": "Asn", "end_pos": 59, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn59", "evidence": [ { "id": "Q08BL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08BL3#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08BL9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 599, "chemical_mass": 67865.0, "gene_names": "klhl24a;klhl24a;klhl24;zgc:153342", "protein_name": "Kelch-like protein 24a", "disease": [ { "disease_id": "DOID:0080326", "name": "familial hypertrophic cardiomyopathy", "description": "A hypertrophic cardiomyopathy that is characterized by thickening of the heart muscle and has_material_basis_in autosomal dominant inheritance of one or more gene mutations.", "url": "https://disease-ontology.org/term/DOID:0080326", "evidence": [ { "id": "0080326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080326" } ], "weight": 0.0 }, { "disease_id": "DOID:4644", "name": "epidermolysis bullosa simplex", "description": "An epidermolysis bullosa that is characterized by recurrent blistering at the level of the epidermis secondary to minor trauma, which can cause limited wounds, dehydration, electrolyte abnormalities, severe infection, among other issues, and has_material_basis_in mutation in the KRT5, KRT14, or PLEC genes, which encode keratin and plectin proteins that provide resilience in skin.", "url": "https://disease-ontology.org/term/DOID:4644", "evidence": [ { "id": "4644", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4644" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "Q08BL9", "url": "https://www.uniprot.org/uniprotkb/Q08BL9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08BW0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 560, "chemical_mass": 60038.0, "gene_names": "otud5a;DUBA;otud5a;otud5;si:bz30i22.1;si:dkey-83k24.3;si:rp71-30i22.1;zgc:154072", "protein_name": "OTU domain-containing protein 5-A", "disease": [], "biological_process": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "positive regulation of TORC2 signaling", "id": "GO:1904515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904515", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "negative regulation of multicellular organismal process", "id": "GO:0051241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051241", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "Q08BW0", "url": "https://www.uniprot.org/uniprotkb/Q08BW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08BY0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08BY0", "url": "https://www.uniprot.org/uniprotkb/Q08BY0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 422, "chemical_mass": 46928.0, "gene_names": "ndufaf7;CH1073-412H12.2;ndufaf7;zgc:153989", "protein_name": "Protein arginine methyltransferase NDUFAF7, mitochondrial", "disease": [], "biological_process": [ { "name": "peptidyl-arginine methylation, to symmetrical-dimethyl arginine", "id": "GO:0019918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019918", "evidence": [ { "database": "UniProtKB", "id": "Q08BY0", "url": "https://www.uniprot.org/uniprotkb/Q08BY0" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "Q08BY0", "url": "https://www.uniprot.org/uniprotkb/Q08BY0" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q08BY0", "url": "https://www.uniprot.org/uniprotkb/Q08BY0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q08BY0", "url": "https://www.uniprot.org/uniprotkb/Q08BY0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-arginine omega-N symmetric methyltransferase activity", "id": "GO:0035243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035243", "evidence": [ { "database": "UniProtKB", "id": "Q08BY0", "url": "https://www.uniprot.org/uniprotkb/Q08BY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08CD5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08CD5", "url": "https://www.uniprot.org/uniprotkb/Q08CD5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 434, "chemical_mass": 50383.0, "gene_names": "rxylt1;rxylt1;tmem5;zgc:153239", "protein_name": "Ribitol-5-phosphate xylosyltransferase 1", "disease": [ { "disease_id": "DOID:0050560", "name": "Walker-Warburg syndrome", "description": "A congenital muscular dystrophy that is characterized by hypotonia, seizures, severe intellectual and developmental disability, eye abnormalities and early death and has_material_basis_in mutations in multiple genes including POMT1, POMT2, ISPD, FKTN, FKRP, and LARGE1.", "url": "https://disease-ontology.org/term/DOID:0050560", "evidence": [ { "id": "0050560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050560" } ], "weight": 0.0 }, { "disease_id": "DOID:0111239", "name": "congenital muscular dystrophy-dystroglycanopathy type A10", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in RXYLT1 on 12q14.2.", "url": "https://disease-ontology.org/term/DOID:0111239", "evidence": [ { "id": "0111239", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111239" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q08CD5", "url": "https://www.uniprot.org/uniprotkb/Q08CD5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q08CD5", "url": "https://www.uniprot.org/uniprotkb/Q08CD5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "Q08CD5", "url": "https://www.uniprot.org/uniprotkb/Q08CD5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribitol beta-1,4-xylosyltransferase activity", "id": "GO:0120053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120053", "evidence": [ { "database": "UniProtKB", "id": "Q08CD5", "url": "https://www.uniprot.org/uniprotkb/Q08CD5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08CF3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 511, "chemical_mass": 57554.0, "gene_names": "ccdc61;ccdc61;zgc:153153", "protein_name": "Centrosomal protein CCDC61", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" }, { "name": "centriolar subdistal appendage", "id": "GO:0120103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120103", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" }, { "name": "centriole assembly", "id": "GO:0098534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098534", "evidence": [ { "database": "UniProtKB", "id": "Q08CF3", "url": "https://www.uniprot.org/uniprotkb/Q08CF3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08CI8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08CI8", "url": "https://www.uniprot.org/uniprotkb/Q08CI8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 287, "chemical_mass": 31161.0, "gene_names": "slc25a38a;slc25a38a;zgc:153036", "protein_name": "Mitochondrial glycine transporter A", "disease": [ { "disease_id": "DOID:0060065", "name": "autosomal recessive pyridoxine-refractory sideroblastic anemia 2", "description": "A sideroblastic anemia that is characterized by microcytic hypochromic anemia and iron overload, and has_material_basis_in autosomal recessive inheritance of mutation in the SLC25A38 gene.", "url": "https://disease-ontology.org/term/DOID:0060065", "evidence": [ { "id": "0060065", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060065" } ], "weight": 0.0 }, { "disease_id": "DOID:8955", "name": "sideroblastic anemia", "description": "A microcytic anemia where the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes).", "url": "https://disease-ontology.org/term/DOID:8955", "evidence": [ { "id": "8955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8955" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "glycine transmembrane transporter activity", "id": "GO:0015187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015187", "evidence": [ { "database": "UniProtKB", "id": "Q08CI8", "url": "https://www.uniprot.org/uniprotkb/Q08CI8" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q08CI8", "url": "https://www.uniprot.org/uniprotkb/Q08CI8" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q08CI8", "url": "https://www.uniprot.org/uniprotkb/Q08CI8" } ], "pmid": "" } ], "biological_process": [ { "name": "hemoglobin metabolic process", "id": "GO:0020027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020027", "evidence": [ { "database": "UniProtKB", "id": "Q08CI8", "url": "https://www.uniprot.org/uniprotkb/Q08CI8" } ], "pmid": "" }, { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "Q08CI8", "url": "https://www.uniprot.org/uniprotkb/Q08CI8" } ], "pmid": "" }, { "name": "hemoglobin biosynthetic process", "id": "GO:0042541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042541", "evidence": [ { "database": "UniProtKB", "id": "Q08CI8", "url": "https://www.uniprot.org/uniprotkb/Q08CI8" } ], "pmid": "" }, { "name": "glycine import into mitochondrion", "id": "GO:1904983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904983", "evidence": [ { "database": "UniProtKB", "id": "Q08CI8", "url": "https://www.uniprot.org/uniprotkb/Q08CI8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08CN9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 217, "chemical_mass": 22638.0, "gene_names": "znrf2;zgc:152865;znrf2b;znrf2", "protein_name": "E3 ubiquitin-protein ligase znrf2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "Q08CN9", "url": "https://www.uniprot.org/uniprotkb/Q08CN9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q08CS6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 572, "chemical_mass": 64050.0, "gene_names": "moxd1l;moxd2;moxd1l;moxd1;moxd2;si:ch211-203k16.5;si:dkeyp-70e6.2;si:dkeyp-95d10.2", "protein_name": "DBH-like monooxygenase protein 2 homolog", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "pmid": "" }, { "name": "secretory granule membrane", "id": "GO:0030667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030667", "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "pmid": "" } ], "molecular_function": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "pmid": "" }, { "name": "dopamine beta-monooxygenase activity", "id": "GO:0004500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004500", "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "pmid": "" } ], "biological_process": [ { "name": "dopamine catabolic process", "id": "GO:0042420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042420", "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "pmid": "" }, { "name": "octopamine biosynthetic process", "id": "GO:0006589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006589", "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "pmid": "" }, { "name": "norepinephrine biosynthetic process", "id": "GO:0042421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042421", "evidence": [ { "database": "UniProtKB", "id": "Q08CS6", "url": "https://www.uniprot.org/uniprotkb/Q08CS6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Asn187", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 187, "start_aa": "Asn", "end_pos": 187, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn187", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Asn203", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 203, "start_aa": "Asn", "end_pos": 203, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn203", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Asn306", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 306, "start_aa": "Asn", "end_pos": 306, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn306", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Asn468", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 468, "start_aa": "Asn", "end_pos": 468, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn468", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Asn503", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 503, "start_aa": "Asn", "end_pos": 503, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn503", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "518", "end_pos": "518", "site_lbl": "Asn518", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 518, "start_aa": "Asn", "end_pos": 518, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn518", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "534", "end_pos": "534", "site_lbl": "Asn534", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 534, "start_aa": "Asn", "end_pos": 534, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn534", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Asn64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 64, "start_aa": "Asn", "end_pos": 64, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn64", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q08CS6-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Asn8", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 8, "start_aa": "Asn", "end_pos": 8, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn8", "evidence": [ { "id": "Q08CS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08CS6#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q0IIP8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q0IIP8", "url": "https://www.uniprot.org/uniprotkb/Q0IIP8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 225, "chemical_mass": 25435.0, "gene_names": "crp", "protein_name": "C-reactive protein", "disease": [ { "disease_id": "DOID:0050452", "name": "mevalonic aciduria", "description": "A peroxisomal disease that is characterized by cortical atrophy, microcephaly, dysmorphic facies, muscular hypotonia and intellectual disability and has_material_basis_in mutation in the MVK gene that results in deficiency of mevalonate kinase and impaired cholesterol. biosynthesis.", "url": "https://disease-ontology.org/term/DOID:0050452", "evidence": [ { "id": "0050452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050452" } ], "weight": 0.0 }, { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0050855", "name": "renal fibrosis", "description": "A kidney disease that is characterized by progressive detrimental connective tissue deposition of the kidney parenchyma leading to deterioration of renal function.", "url": "https://disease-ontology.org/term/DOID:0050855", "evidence": [ { "id": "0050855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050855" } ], "weight": 0.0 }, { "disease_id": "DOID:0050864", "name": "non-arteritic anterior ischemic optic neuropathy", "description": "An anterior ischemic optic neuropathy that is characterized by near-complete vision loss caused by acute ischemic damage to the optic nerve due to non-inflammatory small vessel disease.", "url": "https://disease-ontology.org/term/DOID:0050864", "evidence": [ { "id": "0050864", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050864" } ], "weight": 0.0 }, { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0060322", "name": "mastoiditis", "description": "A middle ear disease characterized by an inflammation of the mucosal lining of the mastoid antrum and the mastoid air cell system inside the mastoid process.", "url": "https://disease-ontology.org/term/DOID:0060322", "evidence": [ { "id": "0060322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060322" } ], "weight": 0.0 }, { "disease_id": "DOID:0070355", "name": "overactive bladder syndrome", "description": "A bladder disease characterized by urinary urgency without urinary tract infection or obvious pathology, usually accompanied by urinary frequency and nocturia.", "url": "https://disease-ontology.org/term/DOID:0070355", "evidence": [ { "id": "0070355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070355" } ], "weight": 0.0 }, { "disease_id": "DOID:0080162", "name": "lupus nephritis", "description": "A glomerulonephritis that is characterized by inflammation of the kidneys resulting from systemic lupus erythematosus.", "url": "https://disease-ontology.org/term/DOID:0080162", "evidence": [ { "id": "0080162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080162" } ], "weight": 0.0 }, { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:1003", "name": "pelvic inflammatory disease", "description": "A female reproductive system disease that is characterized by an infection of the female reproductive organs.", "url": "https://disease-ontology.org/term/DOID:1003", "evidence": [ { "id": "1003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1003" } ], "weight": 0.0 }, { "disease_id": "DOID:104", "name": "bacterial infectious disease", "description": "A disease by infectious agent that results_in infection, has_material_basis_in Bacteria.", "url": "https://disease-ontology.org/term/DOID:104", "evidence": [ { "id": "104", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:104" } ], "weight": 0.0 }, { "disease_id": "DOID:1063", "name": "interstitial nephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:1063", "evidence": [ { "id": "1063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1063" } ], "weight": 0.0 }, { "disease_id": "DOID:1074", "name": "kidney failure", "description": "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood.", "url": "https://disease-ontology.org/term/DOID:1074", "evidence": [ { "id": "1074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1074" } ], "weight": 0.0 }, { "disease_id": "DOID:10754", "name": "otitis media", "description": "A otitis which involves inflammation of the middle ear.", "url": "https://disease-ontology.org/term/DOID:10754", "evidence": [ { "id": "10754", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10754" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10873", "name": "Kuhnt-Junius degeneration", "description": "", "url": "https://disease-ontology.org/term/DOID:10873", "evidence": [ { "id": "10873", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10873" } ], "weight": 0.0 }, { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 }, { "disease_id": "DOID:11561", "name": "hypertensive retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11561", "evidence": [ { "id": "11561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11561" } ], "weight": 0.0 }, { "disease_id": "DOID:12683", "name": "vestibular neuronitis", "description": "A inner ear infectious disease caused by a viral infection which involves inflammation of the vestibular nerve. It usually results as a complication of an upper respiratory infection. This causes sudden and severe vertigo, nausea and vomiting. Auditory symptoms are usually absent.", "url": "https://disease-ontology.org/term/DOID:12683", "evidence": [ { "id": "12683", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12683" } ], "weight": 0.0 }, { "disease_id": "DOID:1287", "name": "cardiovascular system disease", "description": "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.", "url": "https://disease-ontology.org/term/DOID:1287", "evidence": [ { "id": "1287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1287" } ], "weight": 0.0 }, { "disease_id": "DOID:12894", "name": "Sjogren's syndrome", "description": "An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.", "url": "https://disease-ontology.org/term/DOID:12894", "evidence": [ { "id": "12894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12894" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:13276", "name": "Mycoplasma pneumoniae pneumonia", "description": "A bacterial pneumonia that is caused by the bacterial species Mycoplasma pneumoniae. The symptoms include chest pain, chills, dry cough which is not bloody, excessive sweating, fever, headache and sore throat.", "url": "https://disease-ontology.org/term/DOID:13276", "evidence": [ { "id": "13276", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13276" } ], "weight": 0.0 }, { "disease_id": "DOID:13375", "name": "temporal arteritis", "description": "A central nervous system vasculitis that is characterized by inflammation of the lining of arteries, often arteries in the head.", "url": "https://disease-ontology.org/term/DOID:13375", "evidence": [ { "id": "13375", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13375" } ], "weight": 0.0 }, { "disease_id": "DOID:13378", "name": "Kawasaki disease", "description": "A lymphadenitis characterized by swelling of cervical lymph nodes in infants and young children and inflammation of medium-sized blood vessels and that symptoms of fever, congestion of ocular conjunctivae, reddening of lips, reddening of oral cavity, protuberance of tongue papillae and edema of extremities.", "url": "https://disease-ontology.org/term/DOID:13378", "evidence": [ { "id": "13378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13378" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:13544", "name": "low tension glaucoma", "description": "An open-angle glaucoma characterized by increased intrinsic resistance to aqueous outflow without known secondary causes, an anatomically narrow anterior chamber angle, or elevated intraocular pressure compared to the average population. Normal tension glaucoma has_symptom progressive decreased vision and progressive loss of peripheral vision.", "url": "https://disease-ontology.org/term/DOID:13544", "evidence": [ { "id": "13544", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13544" } ], "weight": 0.0 }, { "disease_id": "DOID:13564", "name": "aspergillosis", "description": "An opportunistic mycosis that involves a spectrum of diseases of humans and animals caused by members of the genus Aspergillus infecting lungs, brain, kidney, heart, bone, eyes, sinuses, skin and gastrointestinal tract. It is a serious illnesses in people with a weakened immune system.", "url": "https://disease-ontology.org/term/DOID:13564", "evidence": [ { "id": "13564", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13564" } ], "weight": 0.0 }, { "disease_id": "DOID:13801", "name": "pharyngoconjunctival fever", "description": "A viral infectious disease that results in infection located in pharynx or located in conjunctiva, has_material_basis_in Human adenovirus 3 or 7, serotypes of Mastadenovirus blackbeardi, which are transmitted by droplet spread of respiratory secretions or transmitted by fomites. The infection has symptom fever, has symptom lymphadenopathy of the neck, and has symptom headache.", "url": "https://disease-ontology.org/term/DOID:13801", "evidence": [ { "id": "13801", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13801" } ], "weight": 0.0 }, { "disease_id": "DOID:13949", "name": "interstitial cystitis", "description": "", "url": "https://disease-ontology.org/term/DOID:13949", "evidence": [ { "id": "13949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13949" } ], "weight": 0.0 }, { "disease_id": "DOID:14018", "name": "alcoholic liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14018", "evidence": [ { "id": "14018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14018" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1474", "name": "aggressive periodontitis", "description": "A periodontitis that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as dental plaque and dental calculus resulting in inflammation and a loss of periodontium.", "url": "https://disease-ontology.org/term/DOID:1474", "evidence": [ { "id": "1474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1474" } ], "weight": 0.0 }, { "disease_id": "DOID:1555", "name": "urticaria", "description": "A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis.", "url": "https://disease-ontology.org/term/DOID:1555", "evidence": [ { "id": "1555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1555" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1727", "name": "retinal vein occlusion", "description": "", "url": "https://disease-ontology.org/term/DOID:1727", "evidence": [ { "id": "1727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1727" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2942", "name": "bronchiolitis", "description": "A lung disease that is an inflammation of the bronchioles, the smallest air passages of the lungs. It is caused by viruses and bacteria. The disease has_symptom cough, has_symptom wheezing, has_symptom shortness of breath, has_symptom fever, has_symptom nasal flaring in infants and has_symptom bluish skin due to lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:2942", "evidence": [ { "id": "2942", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2942" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:2988", "name": "antiphospholipid syndrome", "description": "An autoimmune disease that is characterized by recurrent venous or arterial thrombosis and/or fetal losses associated with characteristic elevated levels of antibodies directed against membrane anionic phospholipids (anticardiolipin).", "url": "https://disease-ontology.org/term/DOID:2988", "evidence": [ { "id": "2988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2988" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.", "url": "https://disease-ontology.org/term/DOID:552", "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6039", "name": "uveal melanoma", "description": "A uveal cancer that has_material_basis_in uvea pigment cells.", "url": "https://disease-ontology.org/term/DOID:6039", "evidence": [ { "id": "6039", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6039" } ], "weight": 0.0 }, { "disease_id": "DOID:6088", "name": "acute stress disorder", "description": "An anxiety disorder that has_symptom flashbacks, has_symptom bad dreams, has_symptom frightening thoughts, has_symptom avoidance or has_symptom hyperarousal of PTSD occurring within one month of a traumatic experience as Acute Stress Disorder or ASD.", "url": "https://disease-ontology.org/term/DOID:6088", "evidence": [ { "id": "6088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6088" } ], "weight": 0.0 }, { "disease_id": "DOID:614", "name": "lymphopenia", "description": "A leukopenia that is the condition of having an abnormally low level of lymphocytes in the blood.", "url": "https://disease-ontology.org/term/DOID:614", "evidence": [ { "id": "614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:614" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:676", "name": "systemic juvenile rheumatoid arthritis", "description": "A rheumatoid arthritis that involves an autoimmune disease onset in children under 16 which attacks the healthy cells and tissue of located_in joint.", "url": "https://disease-ontology.org/term/DOID:676", "evidence": [ { "id": "676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:676" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:848", "name": "arthritis", "description": "A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint.", "url": "https://disease-ontology.org/term/DOID:848", "evidence": [ { "id": "848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:848" } ], "weight": 0.0 }, { "disease_id": "DOID:853", "name": "polymyalgia rheumatica", "description": "A collagen disease that is characterized by pain, stiffness, and tenderness of the proximal muscle groups including the shoulder, pelvic girdle and the neck.", "url": "https://disease-ontology.org/term/DOID:853", "evidence": [ { "id": "853", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:853" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:8805", "name": "intermediate coronary syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:8805", "evidence": [ { "id": "8805", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8805" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9463", "name": "otitis externa", "description": "An external ear disease that involves inflammation of the outer ear and ear canal. It can be caused by active bacterial or fungal infections.", "url": "https://disease-ontology.org/term/DOID:9463", "evidence": [ { "id": "9463", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9463" } ], "weight": 0.0 }, { "disease_id": "DOID:9470", "name": "bacterial meningitis", "description": "A meningitis that has_material_basis_in a bacterial infection.", "url": "https://disease-ontology.org/term/DOID:9470", "evidence": [ { "id": "9470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9470" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q0IIP8", "url": "https://www.uniprot.org/uniprotkb/Q0IIP8" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q0IIP8", "url": "https://www.uniprot.org/uniprotkb/Q0IIP8" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "Q0IIP8", "url": "https://www.uniprot.org/uniprotkb/Q0IIP8" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "Q0IIP8", "url": "https://www.uniprot.org/uniprotkb/Q0IIP8" } ], "pmid": "" }, { "name": "acute-phase response", "id": "GO:0006953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "Q0IIP8", "url": "https://www.uniprot.org/uniprotkb/Q0IIP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q0P496-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q0P496", "url": "https://www.uniprot.org/uniprotkb/Q0P496" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 421, "chemical_mass": 46352.0, "gene_names": "marchf4a;marchf4;March4;march4l;march4;marchf4a;marchf4l;marchf4;zgc:153256", "protein_name": "E3 ubiquitin-protein ligase MARCHF4", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q0P496", "url": "https://www.uniprot.org/uniprotkb/Q0P496" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q0P496", "url": "https://www.uniprot.org/uniprotkb/Q0P496" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "Q0P496", "url": "https://www.uniprot.org/uniprotkb/Q0P496" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q0P496", "url": "https://www.uniprot.org/uniprotkb/Q0P496" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q0P496", "url": "https://www.uniprot.org/uniprotkb/Q0P496" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q0P496", "url": "https://www.uniprot.org/uniprotkb/Q0P496" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q0P496", "url": "https://www.uniprot.org/uniprotkb/Q0P496" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q0P499-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 503, "chemical_mass": 57023.0, "gene_names": "ears2;mtGluRS;zgc:153247", "protein_name": "Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial", "disease": [ { "disease_id": "DOID:0111493", "name": "combined oxidative phosphorylation deficiency 12", "description": "A combined oxidative phosphorylation deficiency characterized by infantile onset of hypotonia and delayed psychomotor development or developmental regression that has_material_basis_in homozygous or compound heterozygous mutation in the EARS2 gene on chromosome 16p12.2.", "url": "https://disease-ontology.org/term/DOID:0111493", "evidence": [ { "id": "0111493", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111493" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" }, { "name": "glutamate-tRNA ligase activity", "id": "GO:0004818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004818", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" }, { "name": "glutamate-tRNA(Gln) ligase activity", "id": "GO:0050561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050561", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" }, { "name": "aminoacyl-tRNA ligase activity", "id": "GO:0004812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004812", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" } ], "biological_process": [ { "name": "glutamyl-tRNA aminoacylation", "id": "GO:0006424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006424", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" }, { "name": "tRNA aminoacylation", "id": "GO:0043039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043039", "evidence": [ { "database": "UniProtKB", "id": "Q0P499", "url": "https://www.uniprot.org/uniprotkb/Q0P499" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q0VIA1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 134, "chemical_mass": 15438.0, "gene_names": "med10;med10;png;si:dkey-262j19.1;ten;zgc:112222", "protein_name": "Mediator of RNA polymerase II transcription subunit 10", "disease": [], "biological_process": [ { "name": "atrioventricular canal development", "id": "GO:0036302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036302", "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "pmid": "" }, { "name": "cardiac jelly development", "id": "GO:1905072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905072", "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "pmid": "" } ], "cellular_component": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "Q0VIA1", "url": "https://www.uniprot.org/uniprotkb/Q0VIA1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1ECZ4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 754, "chemical_mass": 82743.0, "gene_names": "casc3;casc3;mln51", "protein_name": "Protein CASC3", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1ECZ4-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Ser477", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q1ECZ4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q1ECZ4" } ] } ] }, { "uniprot_canonical_ac": "Q1ECZ4-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Ser481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q1ECZ4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q1ECZ4" } ] } ] }, { "uniprot_canonical_ac": "Q1ECZ4-1", "start_pos": "483", "end_pos": "483", "site_lbl": "Ser483", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q1ECZ4", "url": "https://www.uniprot.org/uniprotkb/Q1ECZ4" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q1ECZ4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q1ECZ4" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1JPS6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 500, "chemical_mass": 54490.0, "gene_names": "opn4l;opn4.1;opn4c;opn4l;opn4m2;opn4", "protein_name": "Melanopsin-like", "disease": [ { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of locomotor rhythm", "id": "GO:1904059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904059", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" }, { "name": "cellular response to light stimulus", "id": "GO:0071482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071482", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" }, { "name": "phospholipase C-activating opsin-mediated signaling pathway", "id": "GO:0030265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030265", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" } ], "molecular_function": [ { "name": "G protein-coupled photoreceptor activity", "id": "GO:0008020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008020", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" }, { "name": "photoreceptor activity", "id": "GO:0009881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009881", "evidence": [ { "database": "UniProtKB", "id": "Q1JPS6", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1JPS6-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Asn18", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 18, "start_aa": "Asn", "end_pos": 18, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn18", "evidence": [ { "id": "Q1JPS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPS6#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1JPX4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 151, "chemical_mass": 17307.0, "gene_names": "ube2wb;flj11011l;ube2wb;ube2w;zgc:136503", "protein_name": "Probable ubiquitin-conjugating enzyme E2 W-B", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" }, { "name": "protein quality control for misfolded or incompletely synthesized proteins", "id": "GO:0006515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006515", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" }, { "name": "cellular response to misfolded protein", "id": "GO:0071218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071218", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "Q1JPX4", "url": "https://www.uniprot.org/uniprotkb/Q1JPX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1L867-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1L867", "url": "https://www.uniprot.org/uniprotkb/Q1L867" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 207, "chemical_mass": 22756.0, "gene_names": "fndc5b;fndc5b;fndc5;si:dkey-264p5.1;zgc:158684", "protein_name": "Fibronectin type III domain-containing protein 5b", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q1L867", "url": "https://www.uniprot.org/uniprotkb/Q1L867" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "Q1L867", "url": "https://www.uniprot.org/uniprotkb/Q1L867" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q1L867", "url": "https://www.uniprot.org/uniprotkb/Q1L867" } ], "pmid": "" } ], "molecular_function": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "Q1L867", "url": "https://www.uniprot.org/uniprotkb/Q1L867" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1L867-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Asn34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 34, "start_aa": "Asn", "end_pos": 34, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn34", "evidence": [ { "id": "Q1L867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1L867#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q1L867-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Asn79", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 79, "start_aa": "Asn", "end_pos": 79, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn79", "evidence": [ { "id": "Q1L867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1L867#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1L8L6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 701, "chemical_mass": 74943.0, "gene_names": "rnf19b;rnf19b;si:rp71-45k5.9", "protein_name": "E3 ubiquitin-protein ligase RNF19B", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q1L8L6", "url": "https://www.uniprot.org/uniprotkb/Q1L8L6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1L8U8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1436, "chemical_mass": 160025.0, "gene_names": "setdb1a;SETDB1;fc07d03;setdb1a;si:ch211-81a5.6;wu:fc07d03", "protein_name": "Histone-lysine N-methyltransferase SETDB1-A", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "histone H3K9 monomethyltransferase activity", "id": "GO:0140948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140948", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "histone H3K9 dimethyltransferase activity", "id": "GO:0140942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140942", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "histone H3K9me2 methyltransferase activity", "id": "GO:0140947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140947", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "histone H3K14ac reader activity", "id": "GO:0140015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140015", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" }, { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "Q1L8U8", "url": "https://www.uniprot.org/uniprotkb/Q1L8U8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1L8U8-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Thr282", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1L8U8-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Thr404", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1L963-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 998, "chemical_mass": 111825.0, "gene_names": "slc12a10.2;ncc2b;si:dkey-114c3.2;slc12a10.2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" } ], "biological_process": [ { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "chloride transport", "id": "GO:0006821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006821", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "potassium ion homeostasis", "id": "GO:0055075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055075", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "sodium ion homeostasis", "id": "GO:0055078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055078", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "chloride ion homeostasis", "id": "GO:0055064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055064", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium:chloride symporter activity", "id": "GO:0015378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015378", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" }, { "name": "sodium:potassium:chloride symporter activity", "id": "GO:0008511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008511", "evidence": [ { "database": "UniProtKB", "id": "Q1L963", "url": "https://www.uniprot.org/uniprotkb/Q1L963" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1L963-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LU86-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 295, "chemical_mass": 34378.0, "gene_names": "cibar1;cibar1;fam92a1;fam92a;si:dkey-98l21.1;zgc:100998", "protein_name": "CBY1-interacting BAR domain-containing protein 1", "disease": [ { "disease_id": "DOID:1148", "name": "polydactyly", "description": "A physical disorder that is characterized by the presence of more than five fingers per hand or five toes per foot.", "url": "https://disease-ontology.org/term/DOID:1148", "evidence": [ { "id": "1148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1148" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "inner mitochondrial membrane organization", "id": "GO:0007007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007007", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" } ], "cellular_component": [ { "name": "sperm annulus", "id": "GO:0097227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097227", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "Q1LU86", "url": "https://www.uniprot.org/uniprotkb/Q1LU86" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LUU7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LUU7", "url": "https://www.uniprot.org/uniprotkb/Q1LUU7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 618, "chemical_mass": 69303.0, "gene_names": "kifc1;fc27e02;fd14g02;kifc1;knsl2;wu:fc27e02;wu:fd14g02", "protein_name": "Kinesin-like protein", "disease": [], "biological_process": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "Q1LUU7", "url": "https://www.uniprot.org/uniprotkb/Q1LUU7" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "Q1LUU7", "url": "https://www.uniprot.org/uniprotkb/Q1LUU7" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q1LUU7", "url": "https://www.uniprot.org/uniprotkb/Q1LUU7" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q1LUU7", "url": "https://www.uniprot.org/uniprotkb/Q1LUU7" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "Q1LUU7", "url": "https://www.uniprot.org/uniprotkb/Q1LUU7" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q1LUU7", "url": "https://www.uniprot.org/uniprotkb/Q1LUU7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LVF3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LVF3", "url": "https://www.uniprot.org/uniprotkb/Q1LVF3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1180, "chemical_mass": 132344.0, "gene_names": "smg7;fa99h10;smg7;wu:fa99h10", "protein_name": "Nonsense-mediated mRNA decay factor SMG7", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1LVF3", "url": "https://www.uniprot.org/uniprotkb/Q1LVF3" } ], "pmid": "" }, { "name": "telomerase holoenzyme complex", "id": "GO:0005697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005697", "evidence": [ { "database": "UniProtKB", "id": "Q1LVF3", "url": "https://www.uniprot.org/uniprotkb/Q1LVF3" } ], "pmid": "" } ], "molecular_function": [ { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "Q1LVF3", "url": "https://www.uniprot.org/uniprotkb/Q1LVF3" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": "GO:0070034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070034", "evidence": [ { "database": "UniProtKB", "id": "Q1LVF3", "url": "https://www.uniprot.org/uniprotkb/Q1LVF3" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "Q1LVF3", "url": "https://www.uniprot.org/uniprotkb/Q1LVF3" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q1LVF3", "url": "https://www.uniprot.org/uniprotkb/Q1LVF3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LVK9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 858, "chemical_mass": 97085.0, "gene_names": "n4bp1;n4bp1;si:ch211-215n5.3;wu:fi03b05;zgc:66437", "protein_name": "NEDD4-binding protein 1", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "RNA nuclease activity", "id": "GO:0004540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004540", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "negative regulation of cytokine production", "id": "GO:0001818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001818", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" }, { "name": "regulation of innate immune response", "id": "GO:0045088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045088", "evidence": [ { "database": "UniProtKB", "id": "Q1LVK9", "url": "https://www.uniprot.org/uniprotkb/Q1LVK9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LVP6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 391, "chemical_mass": 44635.0, "gene_names": "abraxas1;abra1;abraxas1;abraxas2a;ccdc98;fam175a;si:ch211-85e10.4;zgc:103522", "protein_name": "BRCA1-A complex subunit Abraxas 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" }, { "name": "BRCA1-A complex", "id": "GO:0070531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070531", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" } ], "biological_process": [ { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1LVP6-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q1LVP6", "url": "https://www.uniprot.org/uniprotkb/Q1LVP6" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LWZ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LWZ0", "url": "https://www.uniprot.org/uniprotkb/Q1LWZ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 210, "chemical_mass": 24535.0, "gene_names": "clxn;clxn;efcab1;im:6911536;si:ch211-173p18.9", "protein_name": "Calaxin", "disease": [ { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q1LWZ0", "url": "https://www.uniprot.org/uniprotkb/Q1LWZ0" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q1LWZ0", "url": "https://www.uniprot.org/uniprotkb/Q1LWZ0" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q1LWZ0", "url": "https://www.uniprot.org/uniprotkb/Q1LWZ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q1LWZ0", "url": "https://www.uniprot.org/uniprotkb/Q1LWZ0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "Q1LWZ0", "url": "https://www.uniprot.org/uniprotkb/Q1LWZ0" } ], "pmid": "" }, { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "Q1LWZ0", "url": "https://www.uniprot.org/uniprotkb/Q1LWZ0" } ], "pmid": "" }, { "name": "outer dynein arm assembly", "id": "GO:0036158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036158", "evidence": [ { "database": "UniProtKB", "id": "Q1LWZ0", "url": "https://www.uniprot.org/uniprotkb/Q1LWZ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LX51-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 532, "chemical_mass": 59774.0, "gene_names": "wee2;im:5913035;si:ch211-238n5.5;wee1b;wee2;wu:fi13b10;zgc:123074", "protein_name": "Wee1-like protein kinase 2", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" }, { "name": "regulation of meiosis I", "id": "GO:0060631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060631", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1LX51", "url": "https://www.uniprot.org/uniprotkb/Q1LX51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LXI7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 380, "chemical_mass": 42882.0, "gene_names": "klf2a;etID35223.22;fb08e06;klf2a;wu:fb08e06", "protein_name": "", "disease": [], "biological_process": [ { "name": "atrioventricular valve development", "id": "GO:0003171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003171", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "atrioventricular valve morphogenesis", "id": "GO:0003181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003181", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "nitric oxide biosynthetic process", "id": "GO:0006809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006809", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "negative regulation of mesodermal cell fate specification", "id": "GO:0042662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042662", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "ventricular compact myocardium morphogenesis", "id": "GO:0003223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003223", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "endocardial cushion cell development", "id": "GO:0061444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061444", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "regulation of ectodermal cell fate specification", "id": "GO:0042665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042665", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q1LXI7", "url": "https://www.uniprot.org/uniprotkb/Q1LXI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LXU5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 446, "chemical_mass": 48373.0, "gene_names": "irx5a;iro5;irx5a;ziro5", "protein_name": "Iroquois homeobox protein 5a", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" }, { "name": "regulation of chondrocyte differentiation", "id": "GO:0032330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032330", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" }, { "name": "cell development", "id": "GO:0048468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048468", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" }, { "name": "embryonic skeletal joint development", "id": "GO:0072498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072498", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q1LXU5", "url": "https://www.uniprot.org/uniprotkb/Q1LXU5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LY10-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 495, "chemical_mass": 55876.0, "gene_names": "fsd1;fsd1;si:ch211-232d19.3", "protein_name": "Fibronectin type III and SPRY domain-containing protein 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" }, { "name": "regulation of cell division", "id": "GO:0051302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051302", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1LY10-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Thr167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 167, "start_aa": "Thr", "end_pos": 167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr167", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1LY10-1", "start_pos": "490", "end_pos": "490", "site_lbl": "Ser490", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q1LY10", "url": "https://www.uniprot.org/uniprotkb/Q1LY10" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LY77-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1844, "chemical_mass": 204141.0, "gene_names": "setd1ba;im:7156157;setd1ba;setd1b;si:dkey-237o15.4", "protein_name": "Histone-lysine N-methyltransferase SETD1B-A", "disease": [ { "disease_id": "DOID:0070417", "name": "neurodevelopmental disorder with speech impairment and dysmorphic facies", "description": "A autosomal dominant intellectual developmental disorder characterized by developmental delay associated with mild to moderately impaired intellectual development or learning difficulties, behavioral or psychiatric abnormalities, and delayed speech and language acquisition that has_material_basis_in heterozygous mutation in the SETD1A gene on chromosome 16p11.", "url": "https://disease-ontology.org/term/DOID:0070417", "evidence": [ { "id": "0070417", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070417" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" }, { "name": "histone H3K4 trimethyltransferase activity", "id": "GO:0140999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140999", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" }, { "name": "hematopoietic progenitor cell differentiation", "id": "GO:0002244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1LY77-1", "start_pos": "1219", "end_pos": "1219", "site_lbl": "Thr1219", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1219, "start_aa": "Thr", "end_pos": 1219, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1219", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1LY77-1", "start_pos": "1286", "end_pos": "1286", "site_lbl": "Thr1286", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1286, "start_aa": "Thr", "end_pos": 1286, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1286", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1LY77-1", "start_pos": "1391", "end_pos": "1391", "site_lbl": "Thr1391", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1391, "start_aa": "Thr", "end_pos": 1391, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1391", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1LY77-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Thr399", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1LY77-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Thr477", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1LY77-1", "start_pos": "485", "end_pos": "485", "site_lbl": "Thr485", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 485, "start_aa": "Thr", "end_pos": 485, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr485", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1LY77-1", "start_pos": "551", "end_pos": "551", "site_lbl": "Thr551", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 551, "start_aa": "Thr", "end_pos": 551, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr551", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q1LY77-1", "start_pos": "1138", "end_pos": "1138", "site_lbl": "Ser1138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q1LY77", "url": "https://www.uniprot.org/uniprotkb/Q1LY77" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q1LY77", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q1LY77" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LYB6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 107, "chemical_mass": 12191.0, "gene_names": "atp5if1b;IF(1) B;IF1 B;atp5if1b;atpib;atpif1b;im:6908140;si:ch211-154e15.5;si:ch211-15d5.5;zgc:153321", "protein_name": "ATPase inhibitor B, mitochondrial", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" }, { "name": "ATPase inhibitor activity", "id": "GO:0042030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042030", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" } ], "biological_process": [ { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" }, { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" }, { "name": "heme biosynthetic process", "id": "GO:0006783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006783", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial ATP synthesis coupled proton transport", "id": "GO:1905707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905707", "evidence": [ { "database": "UniProtKB", "id": "Q1LYB6", "url": "https://www.uniprot.org/uniprotkb/Q1LYB6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1LYE1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 612, "chemical_mass": 68518.0, "gene_names": "wee1;fa20h03;wee1;wu:fa20h03;zgc:136514", "protein_name": "Wee1-like protein kinase", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" }, { "name": "response to light stimulus", "id": "GO:0009416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009416", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" }, { "name": "negative regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010972", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/Q1LYE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1MT86-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 853, "chemical_mass": 94797.0, "gene_names": "usp5;usp5;wu:fa06b05;wu:fb36d11;wu:fc21h02;wu:fc61g08;wu:fi41g10;zgc:76990", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "disease": [], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q1MT86", "url": "https://www.uniprot.org/uniprotkb/Q1MT86" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1MTE5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 182, "chemical_mass": 20426.0, "gene_names": "arl3;arl3b;arl3;sfxn2;si:ch211-208d15.4;wu:fj22g05", "protein_name": "ADP-ribosylation factor-like protein 3", "disease": [ { "disease_id": "DOID:0050777", "name": "Joubert syndrome", "description": "A ciliopathy that is characterized by congenital malformation of the brainstem and agenesis or hypoplasia of the cerebellar vermis leading to an abnormal respiratory pattern, nystagmus, hypotonia, ataxia, and delay in achieving motor milestones.", "url": "https://disease-ontology.org/term/DOID:0050777", "evidence": [ { "id": "0050777", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050777" } ], "weight": 0.0 }, { "disease_id": "DOID:0110415", "name": "retinitis pigmentosa 2", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the RP2 gene on chromosome Xp11.3.", "url": "https://disease-ontology.org/term/DOID:0110415", "evidence": [ { "id": "0110415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110415" } ], "weight": 0.0 }, { "disease_id": "DOID:0110861", "name": "autosomal recessive polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion.", "url": "https://disease-ontology.org/term/DOID:0110861", "evidence": [ { "id": "0110861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110861" } ], "weight": 0.0 }, { "disease_id": "DOID:0112140", "name": "retinitis pigmentosa 83", "description": "A retinitis pigmentosa characterized by onset of night blindness in the first decade of life, decreased central vision in the second decade of life, and retinal degeneration that has_material_basis_in heterozygous mutation in ARL3 on chromosome 10q24.32.", "url": "https://disease-ontology.org/term/DOID:0112140", "evidence": [ { "id": "0112140", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112140" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/Q1MTE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q1MTE5-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Thr48", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q1MTI4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 248, "chemical_mass": 26853.0, "gene_names": "tpi1a;DrTPI-A;si:dkey-89b17.2;tpi1a", "protein_name": "Triosephosphate isomerase A", "disease": [ { "disease_id": "DOID:0050884", "name": "triosephosphate isomerase deficiency", "description": "A glucose metabolism disorder that is characterized by chronic haemolytic anaemia, cardiomyopathy, susceptibility to infections and severe neurological dysfunction, and has_material_basis_in the triosephosphate isomerase enzyme (TPI1) gene inherited as an autosomal recessive trait.", "url": "https://disease-ontology.org/term/DOID:0050884", "evidence": [ { "id": "0050884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050884" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:2978", "name": "carbohydrate metabolic disorder", "description": "An inherited metabolic disorder that affect the catabolism and anabolism of carbohydrates.", "url": "https://disease-ontology.org/term/DOID:2978", "evidence": [ { "id": "2978", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2978" } ], "weight": 0.0 }, { "disease_id": "DOID:9282", "name": "ocular hypertension", "description": "An eye disease that is characterized by elevated intraocular pressure in the absence of optic nerve damage or visual field loss.", "url": "https://disease-ontology.org/term/DOID:9282", "evidence": [ { "id": "9282", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9282" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "triose-phosphate isomerase activity", "id": "GO:0004807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004807", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" }, { "name": "methylglyoxal synthase activity", "id": "GO:0008929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008929", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" } ], "biological_process": [ { "name": "glycerol catabolic process", "id": "GO:0019563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019563", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" }, { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" }, { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" }, { "name": "methylglyoxal biosynthetic process", "id": "GO:0019242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019242", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" }, { "name": "glyceraldehyde-3-phosphate biosynthetic process", "id": "GO:0046166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046166", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q1MTI4", "url": "https://www.uniprot.org/uniprotkb/Q1MTI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q20JQ7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1784, "chemical_mass": 201663.0, "gene_names": "scn4ab;Nav1.4b;nav1.4b", "protein_name": "Sodium channel protein type 4 subunit alpha B", "disease": [ { "disease_id": "DOID:0060170", "name": "generalized epilepsy with febrile seizures plus", "description": "An idiopathic generalized epilepsy that is characterized by febrile seizures often with accessory afebrile generalized tonic-clonic seizures with childhood onset.", "url": "https://disease-ontology.org/term/DOID:0060170", "evidence": [ { "id": "0060170", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060170" } ], "weight": 0.0 }, { "disease_id": "DOID:0080422", "name": "Dravet syndrome", "description": "A developmental and epileptic encephalopathy characterized by onset of seizures that are usually refractory to treatment in the first year of life after normal early development and impaired psychomoter development starting around the second year of life that has_material_basis_in heterozygous mutation in the SCN1A gene on chromosome 2q24.", "url": "https://disease-ontology.org/term/DOID:0080422", "evidence": [ { "id": "0080422", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080422" } ], "weight": 0.0 }, { "disease_id": "DOID:0081354", "name": "congenital myopathy 22A", "description": "A congenital myopathy that is characterized by onset of muscle weakness in utero or soon after birth and that has_material_basis_in homozygous or compound heterozygous mutation in the SCN4A gene on chromosome 17q23. Biallelic mutation in the SCN4A gene also causes severe fetal congenital myopathy 22B.", "url": "https://disease-ontology.org/term/DOID:0081354", "evidence": [ { "id": "0081354", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081354" } ], "weight": 0.0 }, { "disease_id": "DOID:0081355", "name": "congenital myopathy 22B", "description": "A congenital myopathy that is characterized by in utero onset of severe muscle weakness manifest as fetal akinesia and that has_material_basis_in homozygous or compound heterozygous mutation in the SCN4A gene on chromosome 17q23.", "url": "https://disease-ontology.org/term/DOID:0081355", "evidence": [ { "id": "0081355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081355" } ], "weight": 0.0 }, { "disease_id": "DOID:0110682", "name": "congenital myasthenic syndrome 16", "description": "A congenital myasthenic syndrome that has_material_basis_in heterozygous or homozygous mutation in the SCN4A gene on chromosome 17q23.", "url": "https://disease-ontology.org/term/DOID:0110682", "evidence": [ { "id": "0110682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110682" } ], "weight": 0.0 }, { "disease_id": "DOID:0111294", "name": "generalized epilepsy with febrile seizures plus 2", "description": "A generalized epilepsy with febrile seizures plus that has_material_basis_in heterozygous mutation in SCN1A on chromosome 2q24.3.", "url": "https://disease-ontology.org/term/DOID:0111294", "evidence": [ { "id": "0111294", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111294" } ], "weight": 0.0 }, { "disease_id": "DOID:0111538", "name": "paramyotonia congenita of Von Eulenburg", "description": "A neuromuscular disease characterized by onset in infancy or early childhood of bouts of myotonia and muscle weakness that are increased by cold exposure that has_material_basis_in heterozygous mutation in the SCN4A gene on chromosome 17q23.3.", "url": "https://disease-ontology.org/term/DOID:0111538", "evidence": [ { "id": "0111538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111538" } ], "weight": 0.0 }, { "disease_id": "DOID:14451", "name": "hyperkalemic periodic paralysis", "description": "", "url": "https://disease-ontology.org/term/DOID:14451", "evidence": [ { "id": "14451", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14451" } ], "weight": 0.0 }, { "disease_id": "DOID:14452", "name": "hypokalemic periodic paralysis", "description": "", "url": "https://disease-ontology.org/term/DOID:14452", "evidence": [ { "id": "14452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14452" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "biological_process": [ { "name": "neuronal action potential", "id": "GO:0019228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019228", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" }, { "name": "sensory perception of pain", "id": "GO:0019233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019233", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" }, { "name": "membrane depolarization during action potential", "id": "GO:0086010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086010", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" }, { "name": "regulation of voltage-gated sodium channel activity", "id": "GO:1905150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905150", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" }, { "name": "voltage-gated sodium channel complex", "id": "GO:0001518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001518", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "voltage-gated sodium channel activity", "id": "GO:0005248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005248", "evidence": [ { "database": "UniProtKB", "id": "Q20JQ7", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q20JQ7-1", "start_pos": "1133", "end_pos": "1133", "site_lbl": "Asn1133", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1133, "start_aa": "Asn", "end_pos": 1133, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1133", "evidence": [ { "id": "Q20JQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q20JQ7-1", "start_pos": "1147", "end_pos": "1147", "site_lbl": "Asn1147", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1147, "start_aa": "Asn", "end_pos": 1147, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1147", "evidence": [ { "id": "Q20JQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q20JQ7-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Asn213", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 213, "start_aa": "Asn", "end_pos": 213, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn213", "evidence": [ { "id": "Q20JQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q20JQ7-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Asn291", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 291, "start_aa": "Asn", "end_pos": 291, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn291", "evidence": [ { "id": "Q20JQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q20JQ7-1", "start_pos": "304", "end_pos": "304", "site_lbl": "Asn304", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 304, "start_aa": "Asn", "end_pos": 304, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn304", "evidence": [ { "id": "Q20JQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q20JQ7-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Asn337", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 337, "start_aa": "Asn", "end_pos": 337, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn337", "evidence": [ { "id": "Q20JQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q20JQ7#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q29R99-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q29R99", "url": "https://www.uniprot.org/uniprotkb/Q29R99" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 224, "chemical_mass": 24664.0, "gene_names": "lipt2;lipt2;zgc:136925", "protein_name": "Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial", "disease": [ { "disease_id": "DOID:543", "name": "dystonia", "description": "A movement disease that is characterized by involuntary muscle contractions causing repetitive or twisting movements.", "url": "https://disease-ontology.org/term/DOID:543", "evidence": [ { "id": "543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:543" } ], "weight": 0.0 }, { "disease_id": "DOID:9268", "name": "glycine encephalopathy", "description": "An amino acid metabolic disorder that involves abnormally high levels of the amino acid glycine in bodily fluids and tissues.", "url": "https://disease-ontology.org/term/DOID:9268", "evidence": [ { "id": "9268", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9268" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q29R99", "url": "https://www.uniprot.org/uniprotkb/Q29R99" } ], "pmid": "" } ], "biological_process": [ { "name": "protein lipoylation", "id": "GO:0009249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009249", "evidence": [ { "database": "UniProtKB", "id": "Q29R99", "url": "https://www.uniprot.org/uniprotkb/Q29R99" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "Q29R99", "url": "https://www.uniprot.org/uniprotkb/Q29R99" } ], "pmid": "" }, { "name": "lipoyl(octanoyl) transferase activity", "id": "GO:0033819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033819", "evidence": [ { "database": "UniProtKB", "id": "Q29R99", "url": "https://www.uniprot.org/uniprotkb/Q29R99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q29RA3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 189, "chemical_mass": 22004.0, "gene_names": "dusp29;dupd1;dusp29;zgc:136906", "protein_name": "Dual specificity phosphatase 29", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "pmid": "" }, { "name": "MAP kinase phosphatase activity", "id": "GO:0033549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033549", "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein dephosphorylation", "id": "GO:0006470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006470", "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "pmid": "" }, { "name": "negative regulation of MAPK cascade", "id": "GO:0043409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043409", "evidence": [ { "database": "UniProtKB", "id": "Q29RA3", "url": "https://www.uniprot.org/uniprotkb/Q29RA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q29RB1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 781, "chemical_mass": 87587.0, "gene_names": "cog4;cog4;zgc:136860", "protein_name": "Conserved oligomeric Golgi complex subunit 4", "disease": [ { "disease_id": "DOID:0070262", "name": "congenital disorder of glycosylation type IIj", "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the COG4 gene on chromosome 16q22.1.", "url": "https://disease-ontology.org/term/DOID:0070262", "evidence": [ { "id": "0070262", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070262" } ], "weight": 0.0 }, { "disease_id": "DOID:0111673", "name": "Saul-Wilson syndrome", "description": "A bone development disease characterized by early developmental delay primarily involving speech, distinct facial features, short stature, brachydactyly, clubfoot deformities, cataracts, and microcephaly that has_material_basis_in heterozygous mutation in the COG4 gene on chromosome 16q22.1.", "url": "https://disease-ontology.org/term/DOID:0111673", "evidence": [ { "id": "0111673", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111673" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "pmid": "" }, { "name": "proteoglycan metabolic process", "id": "GO:0006029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006029", "evidence": [ { "database": "UniProtKB", "id": "Q29RB1", "url": "https://www.uniprot.org/uniprotkb/Q29RB1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q2EY14-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q2EY14", "url": "https://www.uniprot.org/uniprotkb/Q2EY14" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1149, "chemical_mass": 126296.0, "gene_names": "prtga;prtga", "protein_name": "Protogenin A", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q2EY14", "url": "https://www.uniprot.org/uniprotkb/Q2EY14" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q2EY14", "url": "https://www.uniprot.org/uniprotkb/Q2EY14" } ], "pmid": "" }, { "name": "negative regulation of neurogenesis", "id": "GO:0050768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050768", "evidence": [ { "database": "UniProtKB", "id": "Q2EY14", "url": "https://www.uniprot.org/uniprotkb/Q2EY14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Asn230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 230, "start_aa": "Asn", "end_pos": 230, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn230", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Asn300", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 300, "start_aa": "Asn", "end_pos": 300, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn300", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "307", "end_pos": "307", "site_lbl": "Asn307", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 307, "start_aa": "Asn", "end_pos": 307, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn307", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "460", "end_pos": "460", "site_lbl": "Asn460", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 460, "start_aa": "Asn", "end_pos": 460, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn460", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Asn475", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 475, "start_aa": "Asn", "end_pos": 475, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn475", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "617", "end_pos": "617", "site_lbl": "Asn617", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 617, "start_aa": "Asn", "end_pos": 617, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn617", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "720", "end_pos": "720", "site_lbl": "Asn720", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 720, "start_aa": "Asn", "end_pos": 720, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn720", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "741", "end_pos": "741", "site_lbl": "Asn741", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 741, "start_aa": "Asn", "end_pos": 741, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn741", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "753", "end_pos": "753", "site_lbl": "Asn753", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 753, "start_aa": "Asn", "end_pos": 753, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn753", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q2EY14-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Asn78", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 78, "start_aa": "Asn", "end_pos": 78, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn78", "evidence": [ { "id": "Q2EY14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2EY14#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q2KN93-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q2KN93", "url": "https://www.uniprot.org/uniprotkb/Q2KN93" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1132, "chemical_mass": 123627.0, "gene_names": "specc1la;cytsaa;cytsa;im:7159316;si:dkey-118g10.1;specc1la;specc1l", "protein_name": "Cytospin-A", "disease": [ { "disease_id": "DOID:0080698", "name": "Teebi hypertelorism syndrome 1", "description": "A Teebi hypertelorism syndrome that has_material_basis_in mutation in heterozygous mutation in the SPECC1L gene on chromosome 22q11.2 or heterozygous deletion at chromosome 22q11.2.", "url": "https://disease-ontology.org/term/DOID:0080698", "evidence": [ { "id": "0080698", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080698" } ], "weight": 0.0 }, { "disease_id": "DOID:0111706", "name": "oblique facial clefting 1", "description": "An orofacial cleft characterized by a congenital unilateral or bilateral oculo-facial defect beginning at the upper lip lateral to the Cupid's bow, then running lateral to the nasal wing, ending at the the lower eyelid lateral to the inferior punctum that has_material_basis_in heterozygous mutation in the SPECC1L gene on chromosome 22q11.23.", "url": "https://disease-ontology.org/term/DOID:0111706", "evidence": [ { "id": "0111706", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111706" } ], "weight": 0.0 }, { "disease_id": "DOID:674", "name": "cleft palate", "description": "An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.", "url": "https://disease-ontology.org/term/DOID:674", "evidence": [ { "id": "674", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:674" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q2KN93", "url": "https://www.uniprot.org/uniprotkb/Q2KN93" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "Q2KN93", "url": "https://www.uniprot.org/uniprotkb/Q2KN93" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "Q2KN93", "url": "https://www.uniprot.org/uniprotkb/Q2KN93" } ], "pmid": "" }, { "name": "gap junction", "id": "GO:0005921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", "evidence": [ { "database": "UniProtKB", "id": "Q2KN93", "url": "https://www.uniprot.org/uniprotkb/Q2KN93" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q2KN93", "url": "https://www.uniprot.org/uniprotkb/Q2KN93" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "Q2KN93", "url": "https://www.uniprot.org/uniprotkb/Q2KN93" } ], "pmid": "" }, { "name": "face morphogenesis", "id": "GO:0060325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060325", "evidence": [ { "database": "UniProtKB", "id": "Q2KN93", "url": "https://www.uniprot.org/uniprotkb/Q2KN93" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q2KNE5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 593, "chemical_mass": 65529.0, "gene_names": "opn4a;opn4a;opn4d;opn4m1;opn4", "protein_name": "Melanopsin-A", "disease": [ { "disease_id": "DOID:0110372", "name": "retinitis pigmentosa 4", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the RHO gene on chromosome 3q22.", "url": "https://disease-ontology.org/term/DOID:0110372", "evidence": [ { "id": "0110372", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110372" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:5679", "name": "retinal disease", "description": "An eye disease that is located_in the retina.", "url": "https://disease-ontology.org/term/DOID:5679", "evidence": [ { "id": "5679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5679" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "pmid": "" }, { "name": "cellular response to light stimulus", "id": "GO:0071482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071482", "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "pmid": "" } ], "molecular_function": [ { "name": "G protein-coupled photoreceptor activity", "id": "GO:0008020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008020", "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "pmid": "" }, { "name": "photoreceptor activity", "id": "GO:0009881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009881", "evidence": [ { "database": "UniProtKB", "id": "Q2KNE5", "url": "https://www.uniprot.org/uniprotkb/Q2KNE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q2KNE5-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 67, "start_aa": "Thr", "end_pos": 67, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q2PW47-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 989, "chemical_mass": 110862.0, "gene_names": "med24;fc05c04;lsn;med24;thrap4;trap100;wu:fc05c04", "protein_name": "Mediator of RNA polymerase II transcription subunit 24", "disease": [ { "disease_id": "DOID:10487", "name": "Hirschsprung's disease", "description": "A megacolon that is characterized by a blockage of the large intestine due to improper muscle movement in the bowel.", "url": "https://disease-ontology.org/term/DOID:10487", "evidence": [ { "id": "10487", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10487" } ], "weight": 0.0 }, { "disease_id": "DOID:5295", "name": "intestinal disease", "description": "A gastrointestinal system disease that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:5295", "evidence": [ { "id": "5295", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5295" } ], "weight": 0.0 }, { "disease_id": "DOID:870", "name": "neuropathy", "description": "A nervous system disease that is located_in nerves or nerve cells.", "url": "https://disease-ontology.org/term/DOID:870", "evidence": [ { "id": "870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:870" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of transcription initiation by RNA polymerase II", "id": "GO:0060261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060261", "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "pmid": "" }, { "name": "enteric nervous system development", "id": "GO:0048484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048484", "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "pmid": "" }, { "name": "thymus development", "id": "GO:0048538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048538", "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "pmid": "" }, { "name": "retinal cone cell development", "id": "GO:0046549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046549", "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "pmid": "" }, { "name": "interstitial cell of Cajal differentiation", "id": "GO:0061453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061453", "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "pmid": "" } ], "cellular_component": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "Q2PW47", "url": "https://www.uniprot.org/uniprotkb/Q2PW47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6GMG5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 544, "chemical_mass": 58693.0, "gene_names": "impdh1a;IMPD 1a;IMPDH 1a;IMPDH;impdh1a;si:dkey-95h12.3;zgc:91911", "protein_name": "Inosine-5'-monophosphate dehydrogenase 1a", "disease": [ { "disease_id": "DOID:0110216", "name": "Leber congenital amaurosis 11", "description": "A Leber congenital amaurosis that has_material_basis_in mutation n the IMPDH1 gene on chromosome 7q31.3-q32.", "url": "https://disease-ontology.org/term/DOID:0110216", "evidence": [ { "id": "0110216", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110216" } ], "weight": 0.0 }, { "disease_id": "DOID:0110388", "name": "retinitis pigmentosa 10", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the IMPDH1 gene on chromosome 7q32.", "url": "https://disease-ontology.org/term/DOID:0110388", "evidence": [ { "id": "0110388", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110388" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" }, { "name": "IMP dehydrogenase activity", "id": "GO:0003938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003938", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" } ], "biological_process": [ { "name": "developmental pigmentation", "id": "GO:0048066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048066", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" }, { "name": "GTP biosynthetic process", "id": "GO:0006183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006183", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" }, { "name": "'de novo' GMP biosynthetic process", "id": "GO:0106387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106387", "evidence": [ { "database": "UniProtKB", "id": "Q6GMG5", "url": "https://www.uniprot.org/uniprotkb/Q6GMG5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5TZ37-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1716, "chemical_mass": 194674.0, "gene_names": "cdc42bpab;cdc42bpab;fb82d10;si:ch211-89p3.3;wu:fb82d10;zgc:174985", "protein_name": "Serine/threonine-protein kinase MRCK alpha", "disease": [ { "disease_id": "DOID:0060669", "name": "cerebral cavernous malformation", "description": "A cerebrovascular disease that is characterized by dilated blood-filled capillaries lacking structural support.", "url": "https://disease-ontology.org/term/DOID:0060669", "evidence": [ { "id": "0060669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060669" } ], "weight": 0.0 }, { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" }, { "name": "actomyosin", "id": "GO:0042641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042641", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" }, { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ37", "url": "https://www.uniprot.org/uniprotkb/Q5TZ37" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6ZM67-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 937, "chemical_mass": 105658.0, "gene_names": "grin1b;NMDAR1.2;grin1b;si:rp71-1o1.1", "protein_name": "Glutamate receptor", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0070038", "name": "autosomal dominant neurodevelopmental disorder with or without hyperkinetic movements and seizures", "description": "An autosomal dominant intellectual developmental disorder characterized by profound developmental delay, severe intellectual disability with absent speech, muscular hypotonia, and a hyperkinetic movement disorder that has_material_basis_in an autosomal dominant mutation of the GRIN1 gene on chromosome 9q34.3.", "url": "https://disease-ontology.org/term/DOID:0070038", "evidence": [ { "id": "0070038", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070038" } ], "weight": 0.0 }, { "disease_id": "DOID:0070387", "name": "developmental and epileptic encephalopathy 101", "description": "A developmental and epileptic encephalopathy characterized by early infantile epileptic encephalopathy and severe global developmental delay that has_material_basis_in homozygous mutation in the GRIN1 gene on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:0070387", "evidence": [ { "id": "0070387", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070387" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:11206", "name": "opioid abuse", "description": "A substance abuse that involves the recurring use of opioid drugs despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:11206", "evidence": [ { "id": "11206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11206" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:8725", "name": "vascular dementia", "description": "A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.", "url": "https://disease-ontology.org/term/DOID:8725", "evidence": [ { "id": "8725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8725" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "NMDA selective glutamate receptor complex", "id": "GO:0017146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017146", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "NMDA glutamate receptor activity", "id": "GO:0004972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004972", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "ligand-gated channel activity", "id": "GO:0022834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022834", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "ionotropic glutamate receptor signaling pathway", "id": "GO:0035235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035235", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "Q6ZM67", "url": "https://www.uniprot.org/uniprotkb/Q6ZM67" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6AZB3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 311, "chemical_mass": 32902.0, "gene_names": "ciapin1;CIAPIN1;ciapin1;fc46b12;si:ch211-51l3.3-001;wu:fc46b12;zgc:92009", "protein_name": "Anamorsin", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" } ], "molecular_function": [ { "name": "electron transfer activity", "id": "GO:0009055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009055", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q6AZB3", "url": "https://www.uniprot.org/uniprotkb/Q6AZB3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QC34-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QC34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QC34" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1119, "chemical_mass": 126678.0, "gene_names": "adcy7;ADCY4a;adcy7", "protein_name": "adenylate cyclase", "disease": [], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QC34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QC34" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QC34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QC34" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QC34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QC34" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QC34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QC34" } ], "pmid": "" } ], "biological_process": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QC34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QC34" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QC34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QC34" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QC34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QC34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QB25-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QB25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB25" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1113, "chemical_mass": 127128.0, "gene_names": "arhgef9b;arhgef9b;arhgef9;wu:fj33b10", "protein_name": "Rho guanine nucleotide exchange factor 9", "disease": [ { "disease_id": "DOID:0080215", "name": "developmental and epileptic encephalopathy 8", "description": "A developmental and epileptic encephalopathy characterized by seizures with onset before 2 years of age, severe developmental delay, and in some patients hyperekplexia that has_material_basis_in X-linked recessive inheritance of a mutation in the ARHGEF9 gene on chromosome Xq22.1.", "url": "https://disease-ontology.org/term/DOID:0080215", "evidence": [ { "id": "0080215", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080215" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QB25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB25" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QB25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB25" } ], "pmid": "" } ], "biological_process": [ { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QB25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB25" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QB25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB25" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QB25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB25" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q686-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 950, "chemical_mass": 105394.0, "gene_names": "ctnnd1;ctnnd1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080346", "name": "blepharocheilodontic syndrome 2", "description": "A blepharocheilodontic syndrome that has_material_basis_in heterozygous mutation in the CTNND1 gene on chromosome 11q12.", "url": "https://disease-ontology.org/term/DOID:0080346", "evidence": [ { "id": "0080346", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080346" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" }, { "name": "cell migration involved in gastrulation", "id": "GO:0042074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042074", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" }, { "name": "mesodermal cell migration", "id": "GO:0008078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008078", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" }, { "name": "axis elongation", "id": "GO:0003401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003401", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" }, { "name": "posterior lateral line neuromast primordium migration", "id": "GO:0048920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048920", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" } ], "molecular_function": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q686", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q686" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9Q686-1", "start_pos": "349", "end_pos": "349", "site_lbl": "Thr349", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 349, "start_aa": "Thr", "end_pos": 349, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr349", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5PYH5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 827, "chemical_mass": 91496.0, "gene_names": "dlg1b;dlg1l;dlg1b;dlg1l", "protein_name": "Discs large homolog 1-like protein", "disease": [ { "disease_id": "DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.", "url": "https://disease-ontology.org/term/DOID:0060037", "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ], "weight": 0.0 }, { "disease_id": "DOID:0060072", "name": "benign neoplasm", "description": "A disease of cellular proliferation that results in abnormal growths in the body which lack the ability to metastasize.", "url": "https://disease-ontology.org/term/DOID:0060072", "evidence": [ { "id": "0060072", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060072" } ], "weight": 0.0 }, { "disease_id": "DOID:0060419", "name": "chromosome 3q29 microdeletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in deletion of the chromosome 3q29 region.", "url": "https://disease-ontology.org/term/DOID:0060419", "evidence": [ { "id": "0060419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060419" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 }, { "disease_id": "DOID:8991", "name": "cervix uteri carcinoma in situ", "description": "An uterus carcinoma in situ that is located_in the uterine cervix.", "url": "https://disease-ontology.org/term/DOID:8991", "evidence": [ { "id": "8991", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8991" } ], "weight": 0.0 } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "endothelial cell proliferation", "id": "GO:0001935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001935", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "receptor clustering", "id": "GO:0043113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043113", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "protein localization to synapse", "id": "GO:0035418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035418", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "receptor localization to synapse", "id": "GO:0097120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097120", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" } ], "cellular_component": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "ionotropic glutamate receptor binding", "id": "GO:0035255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035255", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH5", "url": "https://www.uniprot.org/uniprotkb/Q5PYH5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5PRD4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 421, "chemical_mass": 48282.0, "gene_names": "csnk1g1;csnk1g1;si:ch211-59b1.2;zgc:101563", "protein_name": "Casein kinase I isoform gamma-1", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "Q5PRD4", "url": "https://www.uniprot.org/uniprotkb/Q5PRD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P698-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 624, "chemical_mass": 69900.0, "gene_names": "lcp1;cb245;fj24b12;pls2;wu:fj24b12", "protein_name": "Plastin-2", "disease": [ { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" }, { "name": "actin filament bundle", "id": "GO:0032432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032432", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "Q6P698", "url": "https://www.uniprot.org/uniprotkb/Q6P698" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SY09-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SY09", "url": "https://www.uniprot.org/uniprotkb/Q7SY09" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 727, "chemical_mass": 81948.0, "gene_names": "adgrl4;eltd1;fd10a02;wu:fd10a02;zgc:63629", "protein_name": "Adhesion G protein-coupled receptor L4", "disease": [ { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q7SY09", "url": "https://www.uniprot.org/uniprotkb/Q7SY09" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q7SY09", "url": "https://www.uniprot.org/uniprotkb/Q7SY09" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7SY09", "url": "https://www.uniprot.org/uniprotkb/Q7SY09" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "Q7SY09", "url": "https://www.uniprot.org/uniprotkb/Q7SY09" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q7SY09", "url": "https://www.uniprot.org/uniprotkb/Q7SY09" } ], "pmid": "" }, { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "Q7SY09", "url": "https://www.uniprot.org/uniprotkb/Q7SY09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7T005-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1183, "chemical_mass": 131440.0, "gene_names": "rab11fip3;si:ch211-153c20.4;zC153C20.4", "protein_name": "Rab11 family-interacting protein 3", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "endocytic vesicle membrane", "id": "GO:0030666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030666", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "regulation of endocytic recycling", "id": "GO:2001135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001135", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" }, { "name": "regulation of protein localization to centrosome", "id": "GO:1904779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904779", "evidence": [ { "database": "UniProtKB", "id": "Q7T005", "url": "https://www.uniprot.org/uniprotkb/Q7T005" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NWC6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 545, "chemical_mass": 58775.0, "gene_names": "cpsf6;cpsf6;wu:fa22f12;zgc:85819", "protein_name": "Cleavage and polyadenylation specificity factor subunit 6", "disease": [], "cellular_component": [ { "name": "perichromatin fibrils", "id": "GO:0005726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005726", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "mRNA cleavage factor complex", "id": "GO:0005849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005849", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "paraspeckles", "id": "GO:0042382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042382", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "interchromatin granule", "id": "GO:0035061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035061", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of RNA export from nucleus", "id": "GO:0046833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046833", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "protein heterotetramerization", "id": "GO:0051290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051290", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "mRNA alternative polyadenylation", "id": "GO:0110104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110104", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "id": "GO:0180010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180010", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6NWC6", "url": "https://www.uniprot.org/uniprotkb/Q6NWC6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6IQE0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 516, "chemical_mass": 55420.0, "gene_names": "puf60b;SIAHBP1;fe37c05;puf60;repressor;si:ch211-12p8.2;si:zc12p8.2;wu:fb33e11;wu:fe37c05;zgc:86806", "protein_name": "Poly(U)-binding-splicing factor PUF60-B", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" }, { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE0", "url": "https://www.uniprot.org/uniprotkb/Q6IQE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6IQE0-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Thr261", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 261, "start_aa": "Thr", "end_pos": 261, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr261", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DEH3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 491, "chemical_mass": 55829.0, "gene_names": "camk2d1;camk2d1;camk2db;wu:fc54g06;zgc:101001;zgc:173815", "protein_name": "Calcium/calmodulin-dependent protein kinase type II delta 1 chain", "disease": [ { "disease_id": "DOID:10273", "name": "heart conduction disease", "description": "A cardiovascular system disease that involves the heart's electrical conduction system.", "url": "https://disease-ontology.org/term/DOID:10273", "evidence": [ { "id": "10273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10273" } ], "weight": 0.0 }, { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" }, { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of protein localization to plasma membrane", "id": "GO:1903076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903076", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" }, { "name": "regulation of neuronal synaptic plasticity", "id": "GO:0048168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048168", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DEH3-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Thr176", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 176, "start_aa": "Thr", "end_pos": 176, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr176", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6DEH3-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Thr286", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ] } ] }, { "uniprot_canonical_ac": "Q6DEH3-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ] } ] }, { "uniprot_canonical_ac": "Q6DEH3-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6DEH3", "url": "https://www.uniprot.org/uniprotkb/Q6DEH3" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q566T0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 443, "chemical_mass": 50616.0, "gene_names": "eed;zgc:112509", "protein_name": "Polycomb protein eed", "disease": [ { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" }, { "name": "digestive tract development", "id": "GO:0048565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048565", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" }, { "name": "exocrine pancreas development", "id": "GO:0031017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031017", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" }, { "name": "regulation of glial cell differentiation", "id": "GO:0045685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045685", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" } ], "cellular_component": [ { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q566T0", "url": "https://www.uniprot.org/uniprotkb/Q566T0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYL5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYL5", "url": "https://www.uniprot.org/uniprotkb/Q6NYL5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 549, "chemical_mass": 61092.0, "gene_names": "gpt2l;gpt;gpt2l;gpt2;gpt;im:6791811;si:ch211-261f3.4;wu:fd46f01", "protein_name": "Alanine aminotransferase 2-like", "disease": [ { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:13603", "name": "obstructive jaundice", "description": "A cholestasis characterized by yellowish pigmentation of the skin and sclera due to high bilirubin levels resulting from biliary tract obstruction.", "url": "https://disease-ontology.org/term/DOID:13603", "evidence": [ { "id": "13603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13603" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver.", "url": "https://disease-ontology.org/term/DOID:3571", "evidence": [ { "id": "3571", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3571" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:9252", "name": "amino acid metabolic disorder", "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.", "url": "https://disease-ontology.org/term/DOID:9252", "evidence": [ { "id": "9252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9252" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NYL5", "url": "https://www.uniprot.org/uniprotkb/Q6NYL5" } ], "pmid": "" } ], "biological_process": [ { "name": "2-oxoglutarate metabolic process", "id": "GO:0006103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006103", "evidence": [ { "database": "UniProtKB", "id": "Q6NYL5", "url": "https://www.uniprot.org/uniprotkb/Q6NYL5" } ], "pmid": "" }, { "name": "L-alanine metabolic process", "id": "GO:0042851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042851", "evidence": [ { "database": "UniProtKB", "id": "Q6NYL5", "url": "https://www.uniprot.org/uniprotkb/Q6NYL5" } ], "pmid": "" }, { "name": "L-alanine catabolic process", "id": "GO:0042853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042853", "evidence": [ { "database": "UniProtKB", "id": "Q6NYL5", "url": "https://www.uniprot.org/uniprotkb/Q6NYL5" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "Q6NYL5", "url": "https://www.uniprot.org/uniprotkb/Q6NYL5" } ], "pmid": "" }, { "name": "L-alanine:2-oxoglutarate aminotransferase activity", "id": "GO:0004021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004021", "evidence": [ { "database": "UniProtKB", "id": "Q6NYL5", "url": "https://www.uniprot.org/uniprotkb/Q6NYL5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYJ3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 616, "chemical_mass": 68075.0, "gene_names": "terf2ip;RAP1;rap1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "disease": [], "biological_process": [ { "name": "telomere maintenance via telomere lengthening", "id": "GO:0010833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010833", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "protection from non-homologous end joining at telomere", "id": "GO:0031848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031848", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "regulation of double-strand break repair via homologous recombination", "id": "GO:0010569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010569", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "negative regulation of DNA recombination at telomere", "id": "GO:0048239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048239", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "shelterin complex", "id": "GO:0070187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070187", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "Q6NYJ3", "url": "https://www.uniprot.org/uniprotkb/Q6NYJ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NYJ3-1", "start_pos": "462", "end_pos": "462", "site_lbl": "Thr462", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 462, "start_aa": "Thr", "end_pos": 462, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr462", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q58EL7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 495, "chemical_mass": 55834.0, "gene_names": "ska3;fc23d11;rama1;si:rp71-68n21.13;wu:fc23d11", "protein_name": "SKA complex subunit 3", "disease": [], "biological_process": [ { "name": "regulation of microtubule polymerization or depolymerization", "id": "GO:0031110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031110", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" } ], "cellular_component": [ { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "meiotic spindle", "id": "GO:0072687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072687", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q58EL7-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Ser295", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q58EL7", "url": "https://www.uniprot.org/uniprotkb/Q58EL7" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q58EL7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q58EL7" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6YBR5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 194, "chemical_mass": 21903.0, "gene_names": "ngfb;ngf;ngfb;ngf;ns:zft386;xx:zft386;zgc:109730", "protein_name": "Nerve growth factor", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:0051061", "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ], "weight": 0.0 }, { "disease_id": "DOID:0051065", "name": "chronic pancreatitis", "description": "A pancreatitis that is characterized by long-term inflamation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:0051065", "evidence": [ { "id": "0051065", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051065" } ], "weight": 0.0 }, { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:0070145", "name": "hereditary sensory and autonomic neuropathy type 5", "description": "A hereditary sensory and autonomic neuropathy characterized by impaired pain and thermal perception in the extremities and selective reduction in small myelinated fibers that has_material_basis_in homozygous mutation in the NGF gene on chromosome 1p13.", "url": "https://disease-ontology.org/term/DOID:0070145", "evidence": [ { "id": "0070145", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070145" } ], "weight": 0.0 }, { "disease_id": "DOID:0070355", "name": "overactive bladder syndrome", "description": "A bladder disease characterized by urinary urgency without urinary tract infection or obvious pathology, usually accompanied by urinary frequency and nocturia.", "url": "https://disease-ontology.org/term/DOID:0070355", "evidence": [ { "id": "0070355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070355" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080809", "name": "chronic asthma", "description": "An asthma that is characterized by the development of persistent airway inflammation and recurrent attacks of breathlessness and wheezing, which vary in severity and frequency.", "url": "https://disease-ontology.org/term/DOID:0080809", "evidence": [ { "id": "0080809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080809" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:0081292", "name": "traumatic brain injury", "description": "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.", "url": "https://disease-ontology.org/term/DOID:0081292", "evidence": [ { "id": "0081292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081292" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10685", "name": "separation anxiety disorder", "description": "An anxiety disorder that involves the feeling of excessive and inappropriate levels of anxiety over being separated from a person to whom the individual has a strong emotional attachment or place.", "url": "https://disease-ontology.org/term/DOID:10685", "evidence": [ { "id": "10685", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10685" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11383", "name": "cryptorchidism", "description": "", "url": "https://disease-ontology.org/term/DOID:11383", "evidence": [ { "id": "11383", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11383" } ], "weight": 0.0 }, { "disease_id": "DOID:12143", "name": "neurogenic bladder", "description": "", "url": "https://disease-ontology.org/term/DOID:12143", "evidence": [ { "id": "12143", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12143" } ], "weight": 0.0 }, { "disease_id": "DOID:1273", "name": "respiratory syncytial virus infectious disease", "description": "A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus (Orthopneumovirus hominis), which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress.", "url": "https://disease-ontology.org/term/DOID:1273", "evidence": [ { "id": "1273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1273" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:13948", "name": "bladder neck obstruction", "description": "", "url": "https://disease-ontology.org/term/DOID:13948", "evidence": [ { "id": "13948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13948" } ], "weight": 0.0 }, { "disease_id": "DOID:13949", "name": "interstitial cystitis", "description": "", "url": "https://disease-ontology.org/term/DOID:13949", "evidence": [ { "id": "13949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13949" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1679", "name": "cystitis", "description": "A bladder disease that is characterized by inflammation of the bladder.", "url": "https://disease-ontology.org/term/DOID:1679", "evidence": [ { "id": "1679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1679" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:2560", "name": "morphine dependence", "description": "An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2560", "evidence": [ { "id": "2560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2560" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3310", "name": "atopic dermatitis", "description": "An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.", "url": "https://disease-ontology.org/term/DOID:3310", "evidence": [ { "id": "3310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3310" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:431", "name": "myofascial pain syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:431", "evidence": [ { "id": "431", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:431" } ], "weight": 0.0 }, { "disease_id": "DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.", "url": "https://disease-ontology.org/term/DOID:4483", "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ], "weight": 0.0 }, { "disease_id": "DOID:5154", "name": "borna disease", "description": "A viral infectious disease that results_in infection, which affects dopaminergic neurotransmission located_in central nervous system, has_material_basis_in Borna disease virus (Orthobornavirus bornaense), which is transmitted_by contact with infected oronasal secretions. The infection has_symptom mood disturbances, has_symptom behaviour disturbances, has_symptom cognitive disturbances, has_symptom neurologic disturbances, and has_symptom movement impairment.", "url": "https://disease-ontology.org/term/DOID:5154", "evidence": [ { "id": "5154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5154" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:90", "name": "degenerative disc disease", "description": "A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc.", "url": "https://disease-ontology.org/term/DOID:90", "evidence": [ { "id": "90", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:90" } ], "weight": 0.0 }, { "disease_id": "DOID:9279", "name": "hyperhomocysteinemia", "description": "An amino acid metabolic disorder that involves an abnormally large level of homocysteine in the blood.", "url": "https://disease-ontology.org/term/DOID:9279", "evidence": [ { "id": "9279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9279" } ], "weight": 0.0 }, { "disease_id": "DOID:9470", "name": "bacterial meningitis", "description": "A meningitis that has_material_basis_in a bacterial infection.", "url": "https://disease-ontology.org/term/DOID:9470", "evidence": [ { "id": "9470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9470" } ], "weight": 0.0 }, { "disease_id": "DOID:9505", "name": "cannabis abuse", "description": "A substance abuse that involves the recurring use of cannabis despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:9505", "evidence": [ { "id": "9505", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9505" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" }, { "name": "nerve development", "id": "GO:0021675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021675", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" }, { "name": "nerve growth factor signaling pathway", "id": "GO:0038180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038180", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" } ], "molecular_function": [ { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" }, { "name": "nerve growth factor receptor binding", "id": "GO:0005163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005163", "evidence": [ { "database": "UniProtKB", "id": "Q6YBR5", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6YBR5-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Asn120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 120, "start_aa": "Asn", "end_pos": 120, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn120", "evidence": [ { "id": "Q6YBR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6YBR5-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Asn99", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 99, "start_aa": "Asn", "end_pos": 99, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn99", "evidence": [ { "id": "Q6YBR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6YBR5#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6QZN6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6QZN6", "url": "https://www.uniprot.org/uniprotkb/Q6QZN6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 821, "chemical_mass": 90721.0, "gene_names": "dact1;dapper1;dpr1;frd1;frodo1", "protein_name": "Dapper homolog 1", "disease": [ { "disease_id": "DOID:0050887", "name": "Townes-Brocks syndrome", "description": "A syndrome that is characterized by imperforate anus, dysplastic ears often associated with sensorineural and/or conductive hearing impairment, and thumb malformations.", "url": "https://disease-ontology.org/term/DOID:0050887", "evidence": [ { "id": "0050887", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050887" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of Wnt signaling pathway, planar cell polarity pathway", "id": "GO:2000095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000095", "evidence": [ { "database": "UniProtKB", "id": "Q6QZN6", "url": "https://www.uniprot.org/uniprotkb/Q6QZN6" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "Q6QZN6", "url": "https://www.uniprot.org/uniprotkb/Q6QZN6" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q6QZN6", "url": "https://www.uniprot.org/uniprotkb/Q6QZN6" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "Q6QZN6", "url": "https://www.uniprot.org/uniprotkb/Q6QZN6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6QZN6", "url": "https://www.uniprot.org/uniprotkb/Q6QZN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q502I3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 435, "chemical_mass": 50949.0, "gene_names": "cep55l;cep55;cep55l;zgc:112184", "protein_name": "Centrosomal protein of 55 kDa", "disease": [ { "disease_id": "DOID:0050778", "name": "Meckel syndrome", "description": "A ciliopathy that is characterized by renal cystic dysplasia, occipital encephalocele, polydactyly (post axial), hepatic developmental defects, and pulmonary hypoplasia.", "url": "https://disease-ontology.org/term/DOID:0050778", "evidence": [ { "id": "0050778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050778" } ], "weight": 0.0 }, { "disease_id": "DOID:0080327", "name": "multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly", "description": "A syndrome that is characterized by severe hydranencephaly with almost complete absence of the cerebral hemispheres, which are replaced by fluid, relative preservation of the posterior fossa structures, and renal dysplasia or agenesis and has_material_basis_in autosomal recessive homozygous mutation in the CEP55 gene on chromosome 10q23.", "url": "https://disease-ontology.org/term/DOID:0080327", "evidence": [ { "id": "0080327", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080327" } ], "weight": 0.0 }, { "disease_id": "DOID:4626", "name": "hydranencephaly", "description": "", "url": "https://disease-ontology.org/term/DOID:4626", "evidence": [ { "id": "4626", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4626" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "establishment of protein localization", "id": "GO:0045184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045184", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "cerebellum development", "id": "GO:0021549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021549", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "Q502I3", "url": "https://www.uniprot.org/uniprotkb/Q502I3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PCR7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1267, "chemical_mass": 151292.0, "gene_names": "eif3a;eif3s10;EIF3A;EIF3S10;eif3s10;wu:fi15c03;zgc:66194;zgc:77263", "protein_name": "Eukaryotic translation initiation factor 3 subunit A", "disease": [], "biological_process": [ { "name": "translation reinitiation", "id": "GO:0002188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002188", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" }, { "name": "multi-eIF complex", "id": "GO:0043614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043614", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex, eIF3e", "id": "GO:0071540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071540", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex, eIF3m", "id": "GO:0071541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071541", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" }, { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "Q6PCR7", "url": "https://www.uniprot.org/uniprotkb/Q6PCR7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PEI3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 754, "chemical_mass": 84195.0, "gene_names": "phactr4b;phactr4b;phactr4;zgc:63484", "protein_name": "Phosphatase and actin regulator 4B", "disease": [], "biological_process": [ { "name": "enteric nervous system development", "id": "GO:0048484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048484", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "closure of optic fissure", "id": "GO:0061386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061386", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "positive regulation of catalytic activity", "id": "GO:0043085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043085", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "negative regulation of integrin-mediated signaling pathway", "id": "GO:2001045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001045", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6PEI3-1", "start_pos": "642", "end_pos": "642", "site_lbl": "Ser642", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI3", "url": "https://www.uniprot.org/uniprotkb/Q6PEI3" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6PEI3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PEI3" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q504H8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 297, "chemical_mass": 33088.0, "gene_names": "hmx3a;hmx3;Nkx5-1;hmx3;nkx-5.1;nkx5-1;nkx5.1;zgc:109845", "protein_name": "Homeobox protein HMX3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "spinal cord development", "id": "GO:0021510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021510", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "inner ear morphogenesis", "id": "GO:0042472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042472", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "otolith development", "id": "GO:0048840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048840", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "posterior lateral line development", "id": "GO:0048916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048916", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "posterior lateral line neuromast primordium migration", "id": "GO:0048920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048920", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q504H8", "url": "https://www.uniprot.org/uniprotkb/Q504H8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q2YDS1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 496, "chemical_mass": 55863.0, "gene_names": "ddb2;si:dkey-45f10.3", "protein_name": "DNA damage-binding protein 2", "disease": [ { "disease_id": "DOID:0050427", "name": "xeroderma pigmentosum", "description": "A syndrome that is characterized by a deficiency in the ability to repair ultraviolet damage that has_material_basis_in autosomal recessive inheritance of DNA repair.", "url": "https://disease-ontology.org/term/DOID:0050427", "evidence": [ { "id": "0050427", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050427" } ], "weight": 0.0 }, { "disease_id": "DOID:0110846", "name": "xeroderma pigmentosum group E", "description": "A xeroderma pigmentosum characterized by a mild phenotype that has_material_basis_in homozygous mutation in the DDB2 gene on chromosome 11p11.", "url": "https://disease-ontology.org/term/DOID:0110846", "evidence": [ { "id": "0110846", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110846" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Cul4A-RING E3 ubiquitin ligase complex", "id": "GO:0031464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031464", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" } ], "molecular_function": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q2YDS1", "url": "https://www.uniprot.org/uniprotkb/Q2YDS1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q67FY3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1530, "chemical_mass": 159872.0, "gene_names": "bcl9l;bcl9-2;bcl9l", "protein_name": "B-cell CLL/lymphoma 9-like protein", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" }, { "name": "lateral mesoderm development", "id": "GO:0048368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048368", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" }, { "name": "post-anal tail morphogenesis", "id": "GO:0036342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036342", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" } ], "cellular_component": [ { "name": "beta-catenin-TCF complex", "id": "GO:1990907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990907", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q67FY3", "url": "https://www.uniprot.org/uniprotkb/Q67FY3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q67FY3-1", "start_pos": "281", "end_pos": "281", "site_lbl": "Thr281", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 281, "start_aa": "Thr", "end_pos": 281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr281", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5PNP1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 934, "chemical_mass": 108143.0, "gene_names": "snx14;si:ch211-241p10.3", "protein_name": "Sorting nexin-14", "disease": [ { "disease_id": "DOID:0080066", "name": "autosomal recessive spinocerebellar ataxia 20", "description": "An autosomal recessive cerebellar ataxia that is characterized by severely delayed psychomotor development with poor or absent speech, wide-based or absent gait, coarse facies, and cerebellar atrophy and that has_material_basis_in homozygous mutation in the SNX14 gene on chromosome 6q14.", "url": "https://disease-ontology.org/term/DOID:0080066", "evidence": [ { "id": "0080066", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080066" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" }, { "name": "hindbrain development", "id": "GO:0030902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030902", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" }, { "name": "cerebellar Purkinje cell layer development", "id": "GO:0021680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021680", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" } ], "cellular_component": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "Q5PNP1", "url": "https://www.uniprot.org/uniprotkb/Q5PNP1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7T163-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1680, "chemical_mass": 185949.0, "gene_names": "kidins220b;arms;dZ119J18.2;fj35h03;kidins220;si:dkeyp-7f8.3;si:dz119j18.2;wu:fj35h03;zgc:63531", "protein_name": "Kinase D-interacting substrate of 220 kDa B", "disease": [], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "pmid": "" }, { "name": "nerve growth factor signaling pathway", "id": "GO:0038180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038180", "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "pmid": "" } ], "cellular_component": [ { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "pmid": "" } ], "molecular_function": [ { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "pmid": "" }, { "name": "protein kinase regulator activity", "id": "GO:0019887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019887", "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q7T163", "url": "https://www.uniprot.org/uniprotkb/Q7T163" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHP9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 452, "chemical_mass": 50140.0, "gene_names": "rxrgb;nr3b3b;rxrgb;si:ch211-260g14.2;zgc:92183", "protein_name": "Retinoic acid receptor RXR-gamma-B", "disease": [ { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "retinoic acid receptor signaling pathway", "id": "GO:0048384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048384", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "nuclear steroid receptor activity", "id": "GO:0003707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003707", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "retinoic acid-responsive element binding", "id": "GO:0044323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044323", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DHP9", "url": "https://www.uniprot.org/uniprotkb/Q6DHP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DHP9-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Thr76", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 76, "start_aa": "Thr", "end_pos": 76, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr76", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXW0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 359, "chemical_mass": 40113.0, "gene_names": "slc25a39;slc25a39;zgc:63736", "protein_name": "Mitochondrial glutathione transporter SLC25A39", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" }, { "name": "metallochaperone activity", "id": "GO:0016530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016530", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" } ], "biological_process": [ { "name": "heme biosynthetic process", "id": "GO:0006783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006783", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" }, { "name": "manganese ion transport", "id": "GO:0006828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006828", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" }, { "name": "mitochondrial transmembrane transport", "id": "GO:1990542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990542", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" }, { "name": "glutathione import into mitochondrion", "id": "GO:0160007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160007", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW0", "url": "https://www.uniprot.org/uniprotkb/Q7SXW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RKN4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 462, "chemical_mass": 50601.0, "gene_names": "glyr1;NPAC;fb96g02;glyr1;np60;wu:fb96g02;zgc:103629", "protein_name": "Cytokine-like nuclear factor N-PAC", "disease": [ { "disease_id": "DOID:0050651", "name": "atrioventricular septal defect", "description": "A congenital heart septal defect characterized by an abnormal or inadequate fusion of the superior and inferior endocardial cushions with the mid portion of the atrial septum and the muscular portion of the ventricular septum, thus allowing extra blood to circulate the lungs.", "url": "https://disease-ontology.org/term/DOID:0050651", "evidence": [ { "id": "0050651", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050651" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" } ], "biological_process": [ { "name": "transcription elongation-coupled chromatin remodeling", "id": "GO:0140673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140673", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN4", "url": "https://www.uniprot.org/uniprotkb/Q5RKN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q708S5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q708S5", "url": "https://www.uniprot.org/uniprotkb/Q708S5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 533, "chemical_mass": 59737.0, "gene_names": "asic2;accn1;asic2;zASIC2", "protein_name": "Acid-sensing ion channel 2", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:14452", "name": "hypokalemic periodic paralysis", "description": "", "url": "https://disease-ontology.org/term/DOID:14452", "evidence": [ { "id": "14452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14452" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q708S5", "url": "https://www.uniprot.org/uniprotkb/Q708S5" } ], "pmid": "" } ], "biological_process": [ { "name": "response to steroid hormone", "id": "GO:0048545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048545", "evidence": [ { "database": "UniProtKB", "id": "Q708S5", "url": "https://www.uniprot.org/uniprotkb/Q708S5" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q708S5", "url": "https://www.uniprot.org/uniprotkb/Q708S5" } ], "pmid": "" } ], "molecular_function": [ { "name": "pH-gated sodium channel activity", "id": "GO:0160125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160125", "evidence": [ { "database": "UniProtKB", "id": "Q708S5", "url": "https://www.uniprot.org/uniprotkb/Q708S5" } ], "pmid": "" }, { "name": "ligand-gated sodium channel activity", "id": "GO:0015280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015280", "evidence": [ { "database": "UniProtKB", "id": "Q708S5", "url": "https://www.uniprot.org/uniprotkb/Q708S5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q708S5-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Asn163", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 163, "start_aa": "Asn", "end_pos": 163, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn163", "evidence": [ { "id": "Q708S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S5-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Asn386", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 386, "start_aa": "Asn", "end_pos": 386, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn386", "evidence": [ { "id": "Q708S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S5-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Asn413", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 413, "start_aa": "Asn", "end_pos": 413, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn413", "evidence": [ { "id": "Q708S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S5#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PFM4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 402, "chemical_mass": 45219.0, "gene_names": "lnpkb;lnpk;fj80c12;lnpb;lnpkb;wu:fj80c12", "protein_name": "Endoplasmic reticulum junction formation protein lunapark-B", "disease": [], "biological_process": [ { "name": "endoplasmic reticulum tubular network organization", "id": "GO:0071786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071786", "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "pmid": "" }, { "name": "positive regulation of endoplasmic reticulum tubular network organization", "id": "GO:1903373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903373", "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network maintenance", "id": "GO:0071788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071788", "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network", "id": "GO:0071782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071782", "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network membrane", "id": "GO:0098826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098826", "evidence": [ { "database": "UniProtKB", "id": "Q6PFM4", "url": "https://www.uniprot.org/uniprotkb/Q6PFM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6PFM4-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Thr208", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DG88-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 394, "chemical_mass": 44453.0, "gene_names": "atg4b;apg4b", "protein_name": "Cysteine protease ATG4B", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "aggrephagy", "id": "GO:0035973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035973", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "microautophagy", "id": "GO:0016237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016237", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "otolith mineralization completed early in development", "id": "GO:0031173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031173", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "protein-phosphatidylethanolamide deconjugating activity", "id": "GO:0019786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019786", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" }, { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "Q6DG88", "url": "https://www.uniprot.org/uniprotkb/Q6DG88" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DG88-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 67, "start_aa": "Thr", "end_pos": 67, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6TH22-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 411, "chemical_mass": 45596.0, "gene_names": "ddi2;ddi2;zgc:63515", "protein_name": "Protein DDI1 homolog 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "proteasomal protein catabolic process", "id": "GO:0010498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010498", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "regulation of DNA stability", "id": "GO:0097752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097752", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "cellular response to hydroxyurea", "id": "GO:0072711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072711", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "Q6TH22", "url": "https://www.uniprot.org/uniprotkb/Q6TH22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6TH22-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 87, "start_aa": "Thr", "end_pos": 87, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr87", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q568L5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 324, "chemical_mass": 36818.0, "gene_names": "akr1a1b;akr1a1b;akr1a1;zgc:110225", "protein_name": "Aldo-keto reductase family 1 member A1-B", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" } ], "molecular_function": [ { "name": "aldose reductase (NADPH) activity", "id": "GO:0004032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004032", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" }, { "name": "alcohol dehydrogenase (NADP+) activity", "id": "GO:0008106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008106", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" }, { "name": "S-nitrosoglutathione reductase (NADPH) activity", "id": "GO:0160163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160163", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" } ], "biological_process": [ { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" }, { "name": "aldehyde catabolic process", "id": "GO:0046185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046185", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" }, { "name": "regulation of gluconeogenesis", "id": "GO:0006111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006111", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" }, { "name": "cellular detoxification of aldehyde", "id": "GO:0110095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110095", "evidence": [ { "database": "UniProtKB", "id": "Q568L5", "url": "https://www.uniprot.org/uniprotkb/Q568L5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXM0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 378, "chemical_mass": 41583.0, "gene_names": "hdac8;phka1a;hdac8;phka1a;wu:fd19a02;zgc:66196", "protein_name": "Histone deacetylase 8", "disease": [ { "disease_id": "DOID:0060814", "name": "Wilson-Turner syndrome", "description": "A syndromic X-linked intellectual disability characterized by intellectual disability, truncal obesity, gynecomastia, hypogonadism, dysmorphic facial features, and short stature that has_material_basis_in hemizygous mutation in the LAS1L gene on chromosome Xq12.", "url": "https://disease-ontology.org/term/DOID:0060814", "evidence": [ { "id": "0060814", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060814" } ], "weight": 0.0 }, { "disease_id": "DOID:0080509", "name": "Cornelia de Lange syndrome 5", "description": "A Cornelia de Lange syndrome that has_material_basis_in by mutation in the HDAC8 gene on chromosome Xq13.", "url": "https://disease-ontology.org/term/DOID:0080509", "evidence": [ { "id": "0080509", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080509" } ], "weight": 0.0 }, { "disease_id": "DOID:0111040", "name": "glycogen storage disease IXd", "description": "A glycogen storage disease IX that is characterized by X-linked inheritance of variable exercise-induced muscle weakness or stiffness that has_material_basis_in mutation in the PHKA1 gene on chromosome Xq13.", "url": "https://disease-ontology.org/term/DOID:0111040", "evidence": [ { "id": "0111040", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111040" } ], "weight": 0.0 }, { "disease_id": "DOID:10487", "name": "Hirschsprung's disease", "description": "A megacolon that is characterized by a blockage of the large intestine due to improper muscle movement in the bowel.", "url": "https://disease-ontology.org/term/DOID:10487", "evidence": [ { "id": "10487", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10487" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11725", "name": "Cornelia de Lange syndrome", "description": "A syndrome that is characterized by slow growth before and after birth, intellectual disability that is usually severe to profound, skeletal abnormalities involving the arms and hands, and distinctive facial features.", "url": "https://disease-ontology.org/term/DOID:11725", "evidence": [ { "id": "11725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11725" } ], "weight": 0.0 }, { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 }, { "disease_id": "DOID:2747", "name": "glycogen storage disease", "description": "A glycogen metabolism disorder that has_material_basis_in enzymes deficiencies necessary in the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types.", "url": "https://disease-ontology.org/term/DOID:2747", "evidence": [ { "id": "2747", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2747" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:670", "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "glycogen metabolic process", "id": "GO:0005977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005977", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "histone deacetylase activity", "id": "GO:0004407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004407", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "histone decrotonylase activity", "id": "GO:0160009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160009", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "histone deacetylase activity, hydrolytic mechanism", "id": "GO:0141221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141221", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "Q7SXM0", "url": "https://www.uniprot.org/uniprotkb/Q7SXM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5EAP5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 734, "chemical_mass": 81854.0, "gene_names": "rfx2;cb133;cb7;rfx2;sb:cb133;sb:cb7;wu:fd20b11;zfx2;zgc:91808", "protein_name": "DNA-binding protein RFX2", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "Kupffer's vesicle development", "id": "GO:0070121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070121", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "Q5EAP5", "url": "https://www.uniprot.org/uniprotkb/Q5EAP5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q68Y21-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1009, "chemical_mass": 113625.0, "gene_names": "grid2;GluD2;glurd2;grid2;si:rp71-1l7.1", "protein_name": "Glutamate receptor ionotropic, delta-2", "disease": [ { "disease_id": "DOID:0080042", "name": "autosomal recessive spinocerebellar ataxia 18", "description": "An autosomal recessive cerebellar ataxia that is characterized by delayed psychomotor development, severely impaired gait due to cerebellar ataxia, ocular movement abnormalities, and intellectual disability and that has_material_basis_in homozygous mutation in the GRID2 gene on chromosome 4q22.", "url": "https://disease-ontology.org/term/DOID:0080042", "evidence": [ { "id": "0080042", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080042" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "AMPA glutamate receptor activity", "id": "GO:0004971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004971", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" } ], "biological_process": [ { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "Q68Y21", "url": "https://www.uniprot.org/uniprotkb/Q68Y21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q68Y21-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Asn293", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 293, "start_aa": "Asn", "end_pos": 293, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn293", "evidence": [ { "id": "Q68Y21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68Y21#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q68Y21-1", "start_pos": "306", "end_pos": "306", "site_lbl": "Asn306", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 306, "start_aa": "Asn", "end_pos": 306, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn306", "evidence": [ { "id": "Q68Y21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68Y21#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q68Y21-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Asn390", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 390, "start_aa": "Asn", "end_pos": 390, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn390", "evidence": [ { "id": "Q68Y21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68Y21#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q68Y21-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Asn426", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 426, "start_aa": "Asn", "end_pos": 426, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn426", "evidence": [ { "id": "Q68Y21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68Y21#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q68Y21-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Asn713", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 713, "start_aa": "Asn", "end_pos": 713, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn713", "evidence": [ { "id": "Q68Y21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68Y21#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q68Y21-1", "start_pos": "992", "end_pos": "992", "site_lbl": "Thr992", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 992, "start_aa": "Thr", "end_pos": 992, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr992", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q567J8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 238, "chemical_mass": 26570.0, "gene_names": "osr2;osr2;zgc:111995", "protein_name": "Protein odd-skipped-related 2", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "urogenital system development", "id": "GO:0001655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001655", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "pattern specification process", "id": "GO:0007389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007389", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "pronephros development", "id": "GO:0048793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048793", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "pectoral fin development", "id": "GO:0033339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033339", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q567J8", "url": "https://www.uniprot.org/uniprotkb/Q567J8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXN4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 635, "chemical_mass": 70733.0, "gene_names": "cpeb4a;cpeb4;Cpeb3;cpeb4a;cpeb4;zgc:66166", "protein_name": "Cytoplasmic polyadenylation element-binding protein 4", "disease": [ { "disease_id": "DOID:10762", "name": "portal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:10762", "evidence": [ { "id": "10762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10762" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": "GO:0000900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "translation factor activity, RNA binding", "id": "GO:0008135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008135", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "translation regulator activity", "id": "GO:0045182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045182", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to decreased oxygen levels", "id": "GO:0036294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036294", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "response to ischemia", "id": "GO:0002931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002931", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "ionotropic glutamate receptor signaling pathway", "id": "GO:0035235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035235", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic translation", "id": "GO:2000766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000766", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q7SXN4", "url": "https://www.uniprot.org/uniprotkb/Q7SXN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7SXN4-1", "start_pos": "224", "end_pos": "224", "site_lbl": "Thr224", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 224, "start_aa": "Thr", "end_pos": 224, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr224", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DEF6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 276, "chemical_mass": 31570.0, "gene_names": "usb1;USB1;usb1;zgc:91896", "protein_name": "U6 snRNA phosphodiesterase 1", "disease": [ { "disease_id": "DOID:0060550", "name": "ablepharon macrostomia syndrome", "description": "A syndrome characterized by ablepharon, macrostomia, abnormal external ears, syndactyly of the hands and feet, dry and coarse skin or redundant folds of skin, absent or sparse hair, genital malformations and developmental delay and that has_material_basis_in heterozygous mutation in the TWIST2 gene on chromosome 2q37.", "url": "https://disease-ontology.org/term/DOID:0060550", "evidence": [ { "id": "0060550", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060550" } ], "weight": 0.0 }, { "disease_id": "DOID:0060551", "name": "poikiloderma with neutropenia", "description": "A skin disease characterized by poikiloderma, hyperkeratotic nails, generalized hyperkeratosis on palms and soles, neutropenia, short stature, and recurrent pulmonary infections and has_material_basis_in mutation in the C16ORF57 gene on chromosome 16q13.", "url": "https://disease-ontology.org/term/DOID:0060551", "evidence": [ { "id": "0060551", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060551" } ], "weight": 0.0 } ], "biological_process": [ { "name": "neutrophil differentiation", "id": "GO:0030223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030223", "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "pmid": "" }, { "name": "U6 snRNA 3'-end processing", "id": "GO:0034477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034477", "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "pmid": "" } ], "molecular_function": [ { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "pmid": "" }, { "name": "poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends", "id": "GO:1990838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990838", "evidence": [ { "database": "UniProtKB", "id": "Q6DEF6", "url": "https://www.uniprot.org/uniprotkb/Q6DEF6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7T293-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 467, "chemical_mass": 51381.0, "gene_names": "sde2;sde2;wu:fb55e02;wu:fi34c02;zgc:112095", "protein_name": "Splicing regulator SDE2", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000479", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q7T293", "url": "https://www.uniprot.org/uniprotkb/Q7T293" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SYD5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1254, "chemical_mass": 135709.0, "gene_names": "sec31a;cb354;sec31l1;sec31p;zgc:63547", "protein_name": "Protein transport protein Sec31A", "disease": [ { "disease_id": "DOID:0070539", "name": "Halperin-Birk syndrome", "description": "A syndrome characterized by structural brain defects, spastic quadriplegia with multiple contractures, profound developmental delay, seizures, dysmorphism, cataract, and optic nerve atrophy that has_material_basis_in homozygous mutation in the SEC31A gene on chromosome 4q21.22.", "url": "https://disease-ontology.org/term/DOID:0070539", "evidence": [ { "id": "0070539", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070539" } ], "weight": 0.0 } ], "biological_process": [ { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "digestive system development", "id": "GO:0055123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055123", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" } ], "cellular_component": [ { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "Q7SYD5", "url": "https://www.uniprot.org/uniprotkb/Q7SYD5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7SYD5-1", "start_pos": "923", "end_pos": "923", "site_lbl": "Thr923", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 923, "start_aa": "Thr", "end_pos": 923, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr923", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5PYH7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 881, "chemical_mass": 98508.0, "gene_names": "dlg2;PSD-93;dlg2", "protein_name": "Disks large homolog 2", "disease": [ { "disease_id": "DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.", "url": "https://disease-ontology.org/term/DOID:0060037", "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ], "weight": 0.0 }, { "disease_id": "DOID:0060072", "name": "benign neoplasm", "description": "A disease of cellular proliferation that results in abnormal growths in the body which lack the ability to metastasize.", "url": "https://disease-ontology.org/term/DOID:0060072", "evidence": [ { "id": "0060072", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060072" } ], "weight": 0.0 }, { "disease_id": "DOID:0060419", "name": "chromosome 3q29 microdeletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in deletion of the chromosome 3q29 region.", "url": "https://disease-ontology.org/term/DOID:0060419", "evidence": [ { "id": "0060419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060419" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "receptor clustering", "id": "GO:0043113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043113", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "protein localization to synapse", "id": "GO:0035418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035418", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "receptor localization to synapse", "id": "GO:0097120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097120", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" } ], "cellular_component": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "ionotropic glutamate receptor binding", "id": "GO:0035255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035255", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "Q5PYH7", "url": "https://www.uniprot.org/uniprotkb/Q5PYH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SY48-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2159, "chemical_mass": 242050.0, "gene_names": "heatr1;BAP28-like;BAP28;fi69e12;flj10359;heatr1;wu:fi69e12;zC146F4.2;zgc:63510", "protein_name": "HEAT repeat-containing protein 1", "disease": [ { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 } ], "biological_process": [ { "name": "protein localization to nucleolus", "id": "GO:1902570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902570", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "regulation of RNA stability", "id": "GO:0043487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043487", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "neural precursor cell proliferation", "id": "GO:0061351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061351", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "rRNA metabolic process", "id": "GO:0016072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016072", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "t-UTP complex", "id": "GO:0034455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034455", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" } ], "molecular_function": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "Q7SY48", "url": "https://www.uniprot.org/uniprotkb/Q7SY48" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXI6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 344, "chemical_mass": 38629.0, "gene_names": "ndel1a;ndel1a", "protein_name": "Nuclear distribution protein nudE-like 1-A", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:1933", "name": "Rubinstein-Taybi syndrome", "description": "A syndrome characterized by short stature, moderate to sever intellectual disability, distinctive facial features and broad thumbs and first toes.", "url": "https://disease-ontology.org/term/DOID:1933", "evidence": [ { "id": "1933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1933" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "vesicle transport along microtubule", "id": "GO:0047496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047496", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "mitotic centrosome separation", "id": "GO:0007100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007100", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" }, { "name": "chromosome localization", "id": "GO:0050000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050000", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI6", "url": "https://www.uniprot.org/uniprotkb/Q7SXI6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7SXI6-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 200, "start_aa": "Thr", "end_pos": 200, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr200", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6IQX0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1503, "chemical_mass": 171098.0, "gene_names": "kdm5bb;cb264;jarid1bb;jarid1b;plu1;si:dkey-193l3.2;wu:fc44h11;zgc:85741", "protein_name": "Lysine-specific demethylase 5B-B", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060809", "name": "syndromic X-linked intellectual disability Claes-Jensen type", "description": "A syndromic X-linked intellectual disability characterized by severe intellectual deficit associated with variable clinical manifestations including spasticity, cryptorchidism, maxillary hypoplasia, alopecia areata, epilepsy, short stature, impaired speech and behavioral problems that has_material_basis_in mutation in the KDM5C gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060809", "evidence": [ { "id": "0060809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060809" } ], "weight": 0.0 }, { "disease_id": "DOID:0081226", "name": "autosomal recessive intellectual developmental disorder 65", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous or compound heterozygous mutation in the KDM5B gene on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081226", "evidence": [ { "id": "0081226", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081226" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:6039", "name": "uveal melanoma", "description": "A uveal cancer that has_material_basis_in uvea pigment cells.", "url": "https://disease-ontology.org/term/DOID:6039", "evidence": [ { "id": "6039", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6039" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "histone H3K4me/H3K4me2/H3K4me3 demethylase activity", "id": "GO:0034647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034647", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q6IQX0", "url": "https://www.uniprot.org/uniprotkb/Q6IQX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q642J5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 373, "chemical_mass": 40309.0, "gene_names": "rbfox1;a2bp1;fox1;rbfox1;zgc:103635", "protein_name": "RNA binding protein fox-1 homolog 1", "disease": [ { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "hypothalamus development", "id": "GO:0021854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021854", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" }, { "name": "left ventricular cardiac muscle tissue morphogenesis", "id": "GO:0003220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003220", "evidence": [ { "database": "UniProtKB", "id": "Q642J5", "url": "https://www.uniprot.org/uniprotkb/Q642J5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q642J5-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Thr51", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6IQ69-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 220, "chemical_mass": 24751.0, "gene_names": "mymk;fb30h02;mymk;si:dkey-191h14.1;tmem8c;wu:fb30h02;zgc:86927", "protein_name": "Protein myomaker", "disease": [ { "disease_id": "DOID:0061115", "name": "Carey-Fineman-Ziter syndrome 1", "description": "A Carey-Fineman-Ziter syndrome characterized by hypotonia, Moebius sequence (bilateral congenital facial palsy with impairment of ocular abduction), Pierre Robin complex (micrognathia, glossoptosis, and high-arched or cleft palate), delayed motor milestones, and failure to thrive that has_material_basis_in homozygous or compound heterozygous mutation in the MYMK gene on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:0061115", "evidence": [ { "id": "0061115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061115" } ], "weight": 0.0 }, { "disease_id": "DOID:0080194", "name": "Carey-Fineman-Ziter syndrome", "description": "A syndrome characterized by hypotonia, Moebius sequence (bilateral congenital facial palsy with impairment of ocular abduction), Pierre Robin complex (micrognathia, glossoptosis, and high-arched or cleft palate), delayed motor milestones, and failure to thrive.", "url": "https://disease-ontology.org/term/DOID:0080194", "evidence": [ { "id": "0080194", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080194" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of skeletal muscle fiber development", "id": "GO:0048742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048742", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "pmid": "" }, { "name": "myoblast fusion", "id": "GO:0007520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007520", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "pmid": "" }, { "name": "positive regulation of skeletal muscle hypertrophy", "id": "GO:1904206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904206", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "pmid": "" }, { "name": "plasma membrane fusion", "id": "GO:0045026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045026", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ69", "url": "https://www.uniprot.org/uniprotkb/Q6IQ69" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RFW2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 711, "chemical_mass": 76880.0, "gene_names": "tab2;map3k7ip2;tab2;zgc:77446", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" }, { "name": "convergent extension involved in gastrulation", "id": "GO:0060027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060027", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q5RFW2", "url": "https://www.uniprot.org/uniprotkb/Q5RFW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4KME6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1329, "chemical_mass": 152268.0, "gene_names": "gigyf2;fb57e02;gigfy2;im:6911549;perq2;tnrc15;wu:fb57e02;zgc:111944", "protein_name": "GRB10-interacting GYF protein 2", "disease": [ { "disease_id": "DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.", "url": "https://disease-ontology.org/term/DOID:0060037", "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": "GO:0000900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "pmid": "" }, { "name": "proximal dendrite", "id": "GO:1990635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990635", "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of translational initiation", "id": "GO:0045947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045947", "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor signaling pathway", "id": "GO:0048009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048009", "evidence": [ { "database": "UniProtKB", "id": "Q4KME6", "url": "https://www.uniprot.org/uniprotkb/Q4KME6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q4KME6-1", "start_pos": "620", "end_pos": "620", "site_lbl": "Thr620", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 620, "start_aa": "Thr", "end_pos": 620, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr620", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NV04-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 621, "chemical_mass": 67036.0, "gene_names": "hacl2;ilvbl;hacl2;ilvbl;zgc:66376;zgc:85697", "protein_name": "2-hydroxyacyl-CoA lyase 2", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "thiamine pyrophosphate binding", "id": "GO:0030976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030976", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "acetolactate synthase activity", "id": "GO:0003984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003984", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "acetolactate synthase complex", "id": "GO:0005948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005948", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" } ], "biological_process": [ { "name": "embryonic cranial skeleton morphogenesis", "id": "GO:0048701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048701", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "fatty acid alpha-oxidation", "id": "GO:0001561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001561", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "L-valine biosynthetic process", "id": "GO:0009099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009099", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "isoleucine biosynthetic process", "id": "GO:0009097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009097", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "Q6NV04", "url": "https://www.uniprot.org/uniprotkb/Q6NV04" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NV04-1", "start_pos": "110", "end_pos": "110", "site_lbl": "Thr110", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 110, "start_aa": "Thr", "end_pos": 110, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr110", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6NV04-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Thr189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6NV04-1", "start_pos": "288", "end_pos": "288", "site_lbl": "Thr288", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 288, "start_aa": "Thr", "end_pos": 288, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr288", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P0J3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 437, "chemical_mass": 45699.0, "gene_names": "sp8b;Sp8a;Sp8;fc48e06;sp8b;sp8l;wu:fc48e06;zgc:77258", "protein_name": "Transcription factor Sp8", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" }, { "name": "embryonic limb morphogenesis", "id": "GO:0030326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030326", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" }, { "name": "positive regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0045743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045743", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" }, { "name": "embryonic pectoral fin morphogenesis", "id": "GO:0035118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035118", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q6P0J3", "url": "https://www.uniprot.org/uniprotkb/Q6P0J3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P0J3-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Thr253", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 253, "start_aa": "Thr", "end_pos": 253, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr253", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q568D5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 386, "chemical_mass": 43829.0, "gene_names": "babam2;babam2;bre;im:7141046;zgc:110368", "protein_name": "BRISC and BRCA1-A complex member 2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "BRISC complex", "id": "GO:0070552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070552", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "BRCA1-A complex", "id": "GO:0070531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070531", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" } ], "molecular_function": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "Q568D5", "url": "https://www.uniprot.org/uniprotkb/Q568D5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYU2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1860, "chemical_mass": 208033.0, "gene_names": "helz;helz;wu:fd51f08;zgc:77407", "protein_name": "ATP-dependent RNA helicase with zinc finger domain", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated post-transcriptional gene silencing", "id": "GO:0035194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035194", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay", "id": "GO:1900153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900153", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU2", "url": "https://www.uniprot.org/uniprotkb/Q6NYU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NYU2-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Thr42", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DI51-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 175, "chemical_mass": 20612.0, "gene_names": "nme6;NDK6;NDPK-Z6;fj33c02;ndpkz6;nme6;wu:fj33c02;zgc:86565", "protein_name": "Nucleoside diphosphate kinase 6, mitochondrial", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "negative regulation of mitotic nuclear division", "id": "GO:0045839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045839", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "GTP biosynthetic process", "id": "GO:0006183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006183", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "UTP biosynthetic process", "id": "GO:0006228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006228", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "CTP biosynthetic process", "id": "GO:0006241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006241", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" }, { "name": "pyrimidine ribonucleotide salvage", "id": "GO:0010138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010138", "evidence": [ { "database": "UniProtKB", "id": "Q6DI51", "url": "https://www.uniprot.org/uniprotkb/Q6DI51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RFU5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 250, "chemical_mass": 28716.0, "gene_names": "mmachc;CblC;fc29d04;si:zfos-47c12.1;wu:fc29d04", "protein_name": "Cyanocobalamin reductase / alkylcobalamin dealkylase", "disease": [ { "disease_id": "DOID:0050715", "name": "methylmalonic aciduria and homocystinuria type cblC", "description": "A methylmalonic acidemia that has_material_basis_in deficiency in synthesis of both AdoCbl and MeCbl (cblC) and is characterized by decreased levels of the coenzymes adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl), which results in decreased activity of the respective enzymes methylmalonyl-CoA mutase.", "url": "https://disease-ontology.org/term/DOID:0050715", "evidence": [ { "id": "0050715", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050715" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" } ], "molecular_function": [ { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" }, { "name": "demethylase activity", "id": "GO:0032451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032451", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" }, { "name": "cobalamin binding", "id": "GO:0031419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031419", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" }, { "name": "cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity", "id": "GO:0033787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033787", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" } ], "biological_process": [ { "name": "cobalamin metabolic process", "id": "GO:0009235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" }, { "name": "regulation of chondrocyte development", "id": "GO:0061181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061181", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" }, { "name": "embryonic viscerocranium morphogenesis", "id": "GO:0048703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048703", "evidence": [ { "database": "UniProtKB", "id": "Q5RFU5", "url": "https://www.uniprot.org/uniprotkb/Q5RFU5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5RFU5-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Thr230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 230, "start_aa": "Thr", "end_pos": 230, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr230", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RHZ6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RHZ6", "url": "https://www.uniprot.org/uniprotkb/Q5RHZ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 335, "chemical_mass": 36728.0, "gene_names": "osgep;fj38e02;osgep;si:ch211-214j24.11;wu:fj38e02;zgc:112527", "protein_name": "tRNA N6-adenosine threonylcarbamoyltransferase", "disease": [ { "disease_id": "DOID:0060879", "name": "primary hypomagnesemia", "description": "A metal metabolism disorder characterized by very low serum magnesium levels often with secondary hypocalcemia with onset typically in the first months of life.", "url": "https://disease-ontology.org/term/DOID:0060879", "evidence": [ { "id": "0060879", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060879" } ], "weight": 0.0 }, { "disease_id": "DOID:0080245", "name": "Galloway-Mowat syndrome 3", "description": "A Galloway-Mowat syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the OSGEP gene on chromosome 14q11.", "url": "https://disease-ontology.org/term/DOID:0080245", "evidence": [ { "id": "0080245", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080245" } ], "weight": 0.0 }, { "disease_id": "DOID:576", "name": "proteinuria", "description": "A kidney disease that is characterized by the presence of excess proteins in the urine.", "url": "https://disease-ontology.org/term/DOID:576", "evidence": [ { "id": "576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:576" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5RHZ6", "url": "https://www.uniprot.org/uniprotkb/Q5RHZ6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5RHZ6", "url": "https://www.uniprot.org/uniprotkb/Q5RHZ6" } ], "pmid": "" }, { "name": "EKC/KEOPS complex", "id": "GO:0000408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000408", "evidence": [ { "database": "UniProtKB", "id": "Q5RHZ6", "url": "https://www.uniprot.org/uniprotkb/Q5RHZ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5RHZ6", "url": "https://www.uniprot.org/uniprotkb/Q5RHZ6" } ], "pmid": "" }, { "name": "tRNA N(6)-L-threonylcarbamoyladenine synthase activity", "id": "GO:0061711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061711", "evidence": [ { "database": "UniProtKB", "id": "Q5RHZ6", "url": "https://www.uniprot.org/uniprotkb/Q5RHZ6" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "Q5RHZ6", "url": "https://www.uniprot.org/uniprotkb/Q5RHZ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5RHZ6-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Thr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P104-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 319, "chemical_mass": 35256.0, "gene_names": "qki2;qki2;qkib;qkic;qkr;zgc:65890;zgc:77340", "protein_name": "Protein quaking-B", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "biological_process": [ { "name": "skeletal myofibril assembly", "id": "GO:0014866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014866", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "negative regulation of macrophage differentiation", "id": "GO:0045650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045650", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "regulation of astrocyte differentiation", "id": "GO:0048710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048710", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "spliceosome-depend formation of circular RNA", "id": "GO:0160091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160091", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P104", "url": "https://www.uniprot.org/uniprotkb/Q6P104" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P104-1", "start_pos": "14", "end_pos": "14", "site_lbl": "Thr14", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 14, "start_aa": "Thr", "end_pos": 14, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr14", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6P104-1", "start_pos": "232", "end_pos": "232", "site_lbl": "Thr232", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 232, "start_aa": "Thr", "end_pos": 232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr232", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6P104-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Thr246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4VBH4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 151, "chemical_mass": 17399.0, "gene_names": "ube2wa;im:6905459;si:ch211-193n21.4;ube2wa;ube2w", "protein_name": "Probable ubiquitin-conjugating enzyme E2 W-A", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" }, { "name": "protein quality control for misfolded or incompletely synthesized proteins", "id": "GO:0006515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006515", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" }, { "name": "cellular response to misfolded protein", "id": "GO:0071218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071218", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "Q4VBH4", "url": "https://www.uniprot.org/uniprotkb/Q4VBH4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXR3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 396, "chemical_mass": 45342.0, "gene_names": "maea;maea;wu:fb20a09;zgc:63708", "protein_name": "E3 ubiquitin-protein transferase MAEA", "disease": [], "biological_process": [ { "name": "erythrocyte maturation", "id": "GO:0043249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043249", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "Q7SXR3", "url": "https://www.uniprot.org/uniprotkb/Q7SXR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PEI7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 591, "chemical_mass": 66595.0, "gene_names": "ctps1a;ctps1;cb1040;ctps1a;ctps1;ctpsa;ctps;wu:fb49e03;wu:fe17b03", "protein_name": "CTP synthase 1", "disease": [ { "disease_id": "DOID:0050625", "name": "biliary tract benign neoplasm", "description": "A hepatobiliary benign neoplasm located_in the biliary tract.", "url": "https://disease-ontology.org/term/DOID:0050625", "evidence": [ { "id": "0050625", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050625" } ], "weight": 0.0 }, { "disease_id": "DOID:0111938", "name": "immunodeficiency 24", "description": "A severe combined immunodeficiency characterized by impaired proliferation of activated T and B cells in response to antigen receptor-mediated activation that has_material_basis_in homozygous or compound heterozygous mutation in the CTPS1 gene on chromosome 1p34.2.", "url": "https://disease-ontology.org/term/DOID:0111938", "evidence": [ { "id": "0111938", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111938" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of chromosome condensation", "id": "GO:1902340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902340", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "notochord development", "id": "GO:0030903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030903", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "'de novo' CTP biosynthetic process", "id": "GO:0044210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044210", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "CTP biosynthetic process", "id": "GO:0006241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006241", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "pyrimidine nucleobase biosynthetic process", "id": "GO:0019856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019856", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "DNA repair-dependent chromatin remodeling", "id": "GO:0140861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140861", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "CTP synthase activity", "id": "GO:0003883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003883", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "protein asparagine deamidase activity", "id": "GO:0160260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160260", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "histone H1N76/N77 asparagine deamidase activity", "id": "GO:0160264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160264", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" }, { "name": "cytoophidium", "id": "GO:0097268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097268", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6PEI7-1", "start_pos": "571", "end_pos": "571", "site_lbl": "Ser571", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6PEI7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PEI7" } ] } ] }, { "uniprot_canonical_ac": "Q6PEI7-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Ser575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6PEI7", "url": "https://www.uniprot.org/uniprotkb/Q6PEI7" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6PEI7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PEI7" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q568Q0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 325, "chemical_mass": 36900.0, "gene_names": "nudt18;nudt18;zgc:110174", "protein_name": "8-oxo-dGDP phosphatase NUDT18", "disease": [], "molecular_function": [ { "name": "8-oxo-dGDP phosphatase activity", "id": "GO:0044715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044715", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" }, { "name": "8-oxo-GDP phosphatase activity", "id": "GO:0044716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044716", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" }, { "name": "8-hydroxy-dADP phosphatase activity", "id": "GO:0044717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044717", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" }, { "name": "farnesyl diphosphatase activity", "id": "GO:0120557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120557", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" }, { "name": "nucleoside diphosphate phosphatase activity", "id": "GO:0017110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017110", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" } ], "biological_process": [ { "name": "dADP catabolic process", "id": "GO:0046057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046057", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" }, { "name": "dGDP catabolic process", "id": "GO:0046067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046067", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" }, { "name": "GDP catabolic process", "id": "GO:0046712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046712", "evidence": [ { "database": "UniProtKB", "id": "Q568Q0", "url": "https://www.uniprot.org/uniprotkb/Q568Q0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5UU75-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 440, "chemical_mass": 47333.0, "gene_names": "dmrta2;Dmrt5;dmrt5", "protein_name": "Doublesex- and mab-3-related transcription factor A2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" }, { "name": "telencephalon development", "id": "GO:0021537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021537", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" }, { "name": "corticotropin hormone secreting cell differentiation", "id": "GO:0060128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060128", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q5UU75", "url": "https://www.uniprot.org/uniprotkb/Q5UU75" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5U3H9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 606, "chemical_mass": 68134.0, "gene_names": "spire2;zgc:103506", "protein_name": "Protein spire homolog 2", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "actin nucleation", "id": "GO:0045010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045010", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "polar body extrusion after meiotic divisions", "id": "GO:0040038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040038", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "establishment of meiotic spindle localization", "id": "GO:0051295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051295", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "formin-nucleated actin cable assembly", "id": "GO:0070649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070649", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair", "id": "GO:2000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000781", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "cleavage furrow formation", "id": "GO:0036089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036089", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H9", "url": "https://www.uniprot.org/uniprotkb/Q5U3H9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5BJA5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 124, "chemical_mass": 13578.0, "gene_names": "ano9a;LOC562630;si:dkey-108k21.20;zgc:112234;zgc:114046", "protein_name": "Histone H2B 1/2", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5BJA5-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Ser111", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_pos": 111, "start_aa": "Ser", "end_pos": 111, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser111", "evidence": [ { "id": "Q5BJA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5BJA5-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Ser13", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q5BJA5", "url": "https://www.uniprot.org/uniprotkb/Q5BJA5" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYY9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 406, "chemical_mass": 45705.0, "gene_names": "vmp1;tmem49;vmp1;wu:fb05d08;wu:fb92g08;zgc:77153", "protein_name": "Vacuole membrane protein 1", "disease": [], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "lipoprotein transport", "id": "GO:0042953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042953", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "Q6NYY9", "url": "https://www.uniprot.org/uniprotkb/Q6NYY9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5U3T3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 245, "chemical_mass": 28504.0, "gene_names": "ctdnep1b;ctdnep1l;dullardl;zgc:101656", "protein_name": "CTD nuclear envelope phosphatase 1B", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" }, { "name": "Nem1-Spo7 phosphatase complex", "id": "GO:0071595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071595", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" }, { "name": "head development", "id": "GO:0060322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060322", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" }, { "name": "positive regulation of triglyceride biosynthetic process", "id": "GO:0010867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010867", "evidence": [ { "database": "UniProtKB", "id": "Q5U3T3", "url": "https://www.uniprot.org/uniprotkb/Q5U3T3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NWK2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 436, "chemical_mass": 49660.0, "gene_names": "ap2m1a;Ap2m1;ap2m1a;cb34;dpy-23;sb:cb34;si:ch211-252f13.2;wu:fa97a10;zgc:55711;zgc:85653", "protein_name": "AP-2 complex subunit mu-A", "disease": [ { "disease_id": "DOID:0061050", "name": "autosomal dominant intellectual developmental disorder 60 with seizures", "description": "An autosomal dominant intellectual developmental disorder characterized by global developmental delay apparent in infancy, followed by onset of seizures in the first years of life that has_material_basis_in heterozygous mutation in the AP2M1 gene on chromosome 3q27.", "url": "https://disease-ontology.org/term/DOID:0061050", "evidence": [ { "id": "0061050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061050" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "AP-2 adaptor complex", "id": "GO:0030122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030122", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "clathrin adaptor complex", "id": "GO:0030131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030131", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" }, { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "Q6NWK2", "url": "https://www.uniprot.org/uniprotkb/Q6NWK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5NDE5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 578, "chemical_mass": 67056.0, "gene_names": "pomgnt2;ago61;glyt;gtdc2;im:7153239;zgc:112079", "protein_name": "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "disease": [ { "disease_id": "DOID:0111231", "name": "congenital muscular dystrophy-dystroglycanopathy type A8", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in POMGNT2 on 3p22.1.", "url": "https://disease-ontology.org/term/DOID:0111231", "evidence": [ { "id": "0111231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111231" } ], "weight": 0.0 }, { "disease_id": "DOID:0112382", "name": "muscular dystrophy-dystroglycanopathy type C8", "description": "A muscular dystrophy-dystroglycanopathy characterized by onset in childhood of a variable phrenotype that ranges from mild intellectual disability and gait abnormalities to asymptomatic that has_material_basis_in homozygous or compound heterozygous mutation in the POMGNT2 gene on chromosome 3p22.1.", "url": "https://disease-ontology.org/term/DOID:0112382", "evidence": [ { "id": "0112382", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112382" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein O-acetylglucosaminyltransferase activity", "id": "GO:0097363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097363", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" }, { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" }, { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" }, { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" }, { "name": "muscle cell development", "id": "GO:0055001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055001", "evidence": [ { "database": "UniProtKB", "id": "Q5NDE5", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5NDE5-1", "start_pos": "275", "end_pos": "275", "site_lbl": "Asn275", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 275, "start_aa": "Asn", "end_pos": 275, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn275", "evidence": [ { "id": "Q5NDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5NDE5-1", "start_pos": "541", "end_pos": "541", "site_lbl": "Asn541", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 541, "start_aa": "Asn", "end_pos": 541, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn541", "evidence": [ { "id": "Q5NDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5NDE5-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Asn98", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 98, "start_aa": "Asn", "end_pos": 98, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn98", "evidence": [ { "id": "Q5NDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5NDE5#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NWG4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 349, "chemical_mass": 39251.0, "gene_names": "prmt6;hrmt1l6;hrmt6;im:6908706", "protein_name": "Protein arginine N-methyltransferase 6", "disease": [ { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glial cell development", "id": "GO:0021782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021782", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "negative regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000059", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-arginine N-methyltransferase activity", "id": "GO:0016274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016274", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "histone H4R3 methyltransferase activity", "id": "GO:0044020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044020", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "protein-arginine omega-N monomethyltransferase activity", "id": "GO:0035241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035241", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "histone H3R2 methyltransferase activity", "id": "GO:0070611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070611", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" }, { "name": "histone H2AR3 methyltransferase activity", "id": "GO:0070612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070612", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG4", "url": "https://www.uniprot.org/uniprotkb/Q6NWG4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7T291-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7T291", "url": "https://www.uniprot.org/uniprotkb/Q7T291" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 322, "chemical_mass": 36645.0, "gene_names": "adprm;adprm;zgc:64213", "protein_name": "Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase", "disease": [], "molecular_function": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "Q7T291", "url": "https://www.uniprot.org/uniprotkb/Q7T291" } ], "pmid": "" }, { "name": "ADP-ribose diphosphatase activity", "id": "GO:0047631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047631", "evidence": [ { "database": "UniProtKB", "id": "Q7T291", "url": "https://www.uniprot.org/uniprotkb/Q7T291" } ], "pmid": "" }, { "name": "CDP-glycerol diphosphatase activity", "id": "GO:0047734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047734", "evidence": [ { "database": "UniProtKB", "id": "Q7T291", "url": "https://www.uniprot.org/uniprotkb/Q7T291" } ], "pmid": "" }, { "name": "2',3'-cyclic-nucleotide 2'-phosphodiesterase activity", "id": "GO:0008663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008663", "evidence": [ { "database": "UniProtKB", "id": "Q7T291", "url": "https://www.uniprot.org/uniprotkb/Q7T291" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7T291-1", "start_pos": "97", "end_pos": "97", "site_lbl": "His97", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Catalytic efficiency is reduced 60-fold with ADP-D-ribose and ADP, 400-fold with CDP-glycerol, 280-fold with CDP-choline and 460-fold with CDP-ethanolamine as substrates.", "evidence": [ { "database": "UniProtKB", "id": "Q7T291", "url": "https://www.uniprot.org/uniprotkb/Q7T291" }, { "database": "PubMed", "id": "22848751", "url": "https://glygen.org/publication/PubMed/22848751" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q59I64-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 468, "chemical_mass": 51234.0, "gene_names": "slc7a6;id:ibd2834;slc7a6", "protein_name": "Y+L amino acid transporter 2", "disease": [], "molecular_function": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "arginine binding", "id": "GO:0034618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034618", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "L-arginine transmembrane transporter activity", "id": "GO:0061459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "L-lysine:L-arginine antiporter activity", "id": "GO:0106439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106439", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" } ], "biological_process": [ { "name": "glycine betaine transport", "id": "GO:0031460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031460", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "neutral amino acid transport", "id": "GO:0015804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015804", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "nitric oxide biosynthetic process", "id": "GO:0006809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006809", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "L-arginine transmembrane transport", "id": "GO:1903826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903826", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q59I64", "url": "https://www.uniprot.org/uniprotkb/Q59I64" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NW52-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 180, "chemical_mass": 19999.0, "gene_names": "msrb2;zgc:85965", "protein_name": "Methionine-R-sulfoxide reductase B2, mitochondrial", "disease": [], "molecular_function": [ { "name": "peptide-methionine (R)-S-oxide reductase activity", "id": "GO:0033743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033743", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" }, { "name": "L-methionine-(R)-S-oxide reductase activity", "id": "GO:0033745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033745", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" }, { "name": "actin filament polymerization", "id": "GO:0030041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030041", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" }, { "name": "protein repair", "id": "GO:0030091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030091", "evidence": [ { "database": "UniProtKB", "id": "Q6NW52", "url": "https://www.uniprot.org/uniprotkb/Q6NW52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q2YDR3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 341, "chemical_mass": 37432.0, "gene_names": "bpnt2;bpnt2;impa3;impad1;zgc:123256", "protein_name": "Inositol monophosphatase 3", "disease": [ { "disease_id": "DOID:0112224", "name": "chondrodysplasia with joint dislocations gPAPP type", "description": "An osteochondrodysplasia characterized by prenatal onset of disproportionate short stature, shortening of the limbs, joint hyperlaxity and/or dislocations, micrognathia, cleft palate, brachydactyly, short metacarpals, supernumerary carpal ossification centers and dysmorphic facial features that has_material_basis_in homozygous or compound heterozygous mutation in the IMPAD1 gene on chromosome 8q12.", "url": "https://disease-ontology.org/term/DOID:0112224", "evidence": [ { "id": "0112224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112224" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "3'-nucleotidase activity", "id": "GO:0008254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008254", "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "pmid": "" }, { "name": "inositol monophosphate phosphatase activity", "id": "GO:0052834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052834", "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "pmid": "" } ], "biological_process": [ { "name": "inositol biosynthetic process", "id": "GO:0006021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006021", "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "Q2YDR3", "url": "https://www.uniprot.org/uniprotkb/Q2YDR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q32LT7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q32LT7", "url": "https://www.uniprot.org/uniprotkb/Q32LT7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 560, "chemical_mass": 62192.0, "gene_names": "ttyh3b;fj56f11;ttyh3;wu:fj56f11;zgc:123242", "protein_name": "Protein tweety homolog 3", "disease": [], "molecular_function": [ { "name": "volume-sensitive chloride channel activity", "id": "GO:0072320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072320", "evidence": [ { "database": "UniProtKB", "id": "Q32LT7", "url": "https://www.uniprot.org/uniprotkb/Q32LT7" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q32LT7", "url": "https://www.uniprot.org/uniprotkb/Q32LT7" } ], "pmid": "" }, { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "Q32LT7", "url": "https://www.uniprot.org/uniprotkb/Q32LT7" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "Q32LT7", "url": "https://www.uniprot.org/uniprotkb/Q32LT7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q32LT7", "url": "https://www.uniprot.org/uniprotkb/Q32LT7" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "Q32LT7", "url": "https://www.uniprot.org/uniprotkb/Q32LT7" } ], "pmid": "" } ], "biological_process": [ { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "Q32LT7", "url": "https://www.uniprot.org/uniprotkb/Q32LT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q32LT7-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Asn127", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 127, "start_aa": "Asn", "end_pos": 127, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn127", "evidence": [ { "id": "Q32LT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LT7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q32LT7-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Asn145", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 145, "start_aa": "Asn", "end_pos": 145, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn145", "evidence": [ { "id": "Q32LT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LT7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q32LT7-1", "start_pos": "352", "end_pos": "352", "site_lbl": "Asn352", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 352, "start_aa": "Asn", "end_pos": 352, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn352", "evidence": [ { "id": "Q32LT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LT7#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q32LU1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 617, "chemical_mass": 69740.0, "gene_names": "rhot2;miro2;rhot2;zgc:123249", "protein_name": "Mitochondrial Rho GTPase 2", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitochondrion transport along microtubule", "id": "GO:0047497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047497", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "cellular homeostasis", "id": "GO:0019725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019725", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "mitochondrial outer membrane permeabilization", "id": "GO:0097345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097345", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q32LU1", "url": "https://www.uniprot.org/uniprotkb/Q32LU1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q32PL8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 523, "chemical_mass": 60194.0, "gene_names": "primpol;ccdc111;primpol;zgc:123274", "protein_name": "DNA-directed primase/polymerase protein", "disease": [ { "disease_id": "DOID:11830", "name": "myopia", "description": "A refractive error characterized by the inability to see farther objects clearly.", "url": "https://disease-ontology.org/term/DOID:11830", "evidence": [ { "id": "11830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11830" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA-directed DNA polymerase activity", "id": "GO:0003887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003887", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase complex", "id": "GO:0000428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000428", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" } ], "biological_process": [ { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "mitochondrial DNA replication", "id": "GO:0006264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006264", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "mitochondrial DNA repair", "id": "GO:0043504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043504", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" }, { "name": "R-loop processing", "id": "GO:0062176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062176", "evidence": [ { "database": "UniProtKB", "id": "Q32PL8", "url": "https://www.uniprot.org/uniprotkb/Q32PL8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q3B752-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 212, "chemical_mass": 24133.0, "gene_names": "dtymk;dtymk;tymk;wu:fa12c02;wu:fb14h07;wu:ft84f02;zgc:123174", "protein_name": "Thymidylate kinase", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" }, { "name": "dTMP kinase activity", "id": "GO:0004798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004798", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" }, { "name": "central nervous system neuron development", "id": "GO:0021954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021954", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" }, { "name": "dTDP biosynthetic process", "id": "GO:0006233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006233", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" }, { "name": "dUDP biosynthetic process", "id": "GO:0006227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006227", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" }, { "name": "dTTP biosynthetic process", "id": "GO:0006235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006235", "evidence": [ { "database": "UniProtKB", "id": "Q3B752", "url": "https://www.uniprot.org/uniprotkb/Q3B752" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q49GP5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 501, "chemical_mass": 56199.0, "gene_names": "pi4k2b;pi4k2b;zgc:158305", "protein_name": "Phosphatidylinositol 4-kinase type 2-beta", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "1-phosphatidylinositol 4-kinase activity", "id": "GO:0004430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004430", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" } ], "biological_process": [ { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" }, { "name": "pectoral fin development", "id": "GO:0033339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033339", "evidence": [ { "database": "UniProtKB", "id": "Q49GP5", "url": "https://www.uniprot.org/uniprotkb/Q49GP5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4KML2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4KML2", "url": "https://www.uniprot.org/uniprotkb/Q4KML2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 520, "chemical_mass": 59922.0, "gene_names": "cry-dash;cry-dash;zcry-dash", "protein_name": "Cryptochrome DASH", "disease": [], "molecular_function": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "Q4KML2", "url": "https://www.uniprot.org/uniprotkb/Q4KML2" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "Q4KML2", "url": "https://www.uniprot.org/uniprotkb/Q4KML2" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q4KML2", "url": "https://www.uniprot.org/uniprotkb/Q4KML2" } ], "pmid": "" }, { "name": "deoxyribodipyrimidine photo-lyase activity", "id": "GO:0003904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003904", "evidence": [ { "database": "UniProtKB", "id": "Q4KML2", "url": "https://www.uniprot.org/uniprotkb/Q4KML2" } ], "pmid": "" } ], "biological_process": [ { "name": "photoreactive repair", "id": "GO:0000719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000719", "evidence": [ { "database": "UniProtKB", "id": "Q4KML2", "url": "https://www.uniprot.org/uniprotkb/Q4KML2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4U0S5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 503, "chemical_mass": 58216.0, "gene_names": "paf1;aln;im:6906070;paf1l;paf1;wu:fb80a09", "protein_name": "RNA polymerase II-associated factor 1 homolog", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "pmid": "" }, { "name": "neural crest cell development", "id": "GO:0014032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014032", "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "pmid": "" }, { "name": "Cdc73/Paf1 complex", "id": "GO:0016593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "evidence": [ { "database": "UniProtKB", "id": "Q4U0S5", "url": "https://www.uniprot.org/uniprotkb/Q4U0S5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4V8R6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 719, "chemical_mass": 80136.0, "gene_names": "e4f1;e4f1;zgc:114190", "protein_name": "Transcription factor E4F1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R6", "url": "https://www.uniprot.org/uniprotkb/Q4V8R6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4V8R7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 455, "chemical_mass": 52019.0, "gene_names": "nr6a1b;GCNF-B;gcnf;nr6a1b;si:ch211-167p9.1;zC167P9.1;zgc:114189", "protein_name": "Nuclear receptor subfamily 6 group A member 1-B", "disease": [], "molecular_function": [ { "name": "estrogen response element binding", "id": "GO:0034056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034056", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "hormone binding", "id": "GO:0042562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042562", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "response to lipid", "id": "GO:0033993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033993", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "midbrain-hindbrain boundary development", "id": "GO:0030917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030917", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "pronephros development", "id": "GO:0048793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048793", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" }, { "name": "regulation of sclerotome development", "id": "GO:0061190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061190", "evidence": [ { "database": "UniProtKB", "id": "Q4V8R7", "url": "https://www.uniprot.org/uniprotkb/Q4V8R7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4V8X4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4V8X4", "url": "https://www.uniprot.org/uniprotkb/Q4V8X4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 300, "chemical_mass": 32662.0, "gene_names": "acbd6;acbd6;fc69g03;wu:fc18d09;wu:fc69g03", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4V8X4", "url": "https://www.uniprot.org/uniprotkb/Q4V8X4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q4V8X4", "url": "https://www.uniprot.org/uniprotkb/Q4V8X4" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q4V8X4", "url": "https://www.uniprot.org/uniprotkb/Q4V8X4" } ], "pmid": "" }, { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "Q4V8X4", "url": "https://www.uniprot.org/uniprotkb/Q4V8X4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4V908-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 221, "chemical_mass": 24149.0, "gene_names": "ube2s;ube2s;zgc:114060", "protein_name": "Ubiquitin-conjugating enzyme E2 S", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "exit from mitosis", "id": "GO:0010458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010458", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "positive regulation of ubiquitin protein ligase activity", "id": "GO:1904668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904668", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" }, { "name": "free ubiquitin chain polymerization", "id": "GO:0010994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010994", "evidence": [ { "database": "UniProtKB", "id": "Q4V908", "url": "https://www.uniprot.org/uniprotkb/Q4V908" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4V9H3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 360, "chemical_mass": 40085.0, "gene_names": "draxin;neucrin;zgc:113312", "protein_name": "Draxin", "disease": [], "biological_process": [ { "name": "dorsal spinal cord development", "id": "GO:0021516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021516", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" }, { "name": "commissural neuron differentiation in spinal cord", "id": "GO:0021528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021528", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q4V9H3", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q4V9H3-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Asn269", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 269, "start_aa": "Asn", "end_pos": 269, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn269", "evidence": [ { "id": "Q4V9H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3#ptm_processing" }, { "id": "MF_03060", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/MF_03060" } ] } ] }, { "uniprot_canonical_ac": "Q4V9H3-1", "start_pos": "274", "end_pos": "274", "site_lbl": "Asn274", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 274, "start_aa": "Asn", "end_pos": 274, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn274", "evidence": [ { "id": "Q4V9H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4V9H3#ptm_processing" }, { "id": "MF_03060", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/MF_03060" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q4W898-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 242, "chemical_mass": 26765.0, "gene_names": "tnfb;Tnf-alpha;tnfa-like;tnfb;tnf", "protein_name": "Lymphotoxin-alpha", "disease": [ { "disease_id": "DOID:0050127", "name": "sinusitis", "description": "A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip.", "url": "https://disease-ontology.org/term/DOID:0050127", "evidence": [ { "id": "0050127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050127" } ], "weight": 0.0 }, { "disease_id": "DOID:0050156", "name": "idiopathic pulmonary fibrosis", "description": "A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.", "url": "https://disease-ontology.org/term/DOID:0050156", "evidence": [ { "id": "0050156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050156" } ], "weight": 0.0 }, { "disease_id": "DOID:0050426", "name": "Stevens-Johnson syndrome", "description": "A skin disease that is characterized by ulceration of less than 10 percent of the surface area of the body. The disease is often precipitated by the use of medications, such as antibiotics or antiepileptics, or onset of infection.", "url": "https://disease-ontology.org/term/DOID:0050426", "evidence": [ { "id": "0050426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050426" } ], "weight": 0.0 }, { "disease_id": "DOID:0050452", "name": "mevalonic aciduria", "description": "A peroxisomal disease that is characterized by cortical atrophy, microcephaly, dysmorphic facies, muscular hypotonia and intellectual disability and has_material_basis_in mutation in the MVK gene that results in deficiency of mevalonate kinase and impaired cholesterol. biosynthesis.", "url": "https://disease-ontology.org/term/DOID:0050452", "evidence": [ { "id": "0050452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050452" } ], "weight": 0.0 }, { "disease_id": "DOID:0050475", "name": "Weill-Marchesani syndrome", "description": "A syndrome characterized by short stature, brachycephaly and other facial abnormalities, brachydactyly, joint stiffness and distinctive ocular abnormalities.", "url": "https://disease-ontology.org/term/DOID:0050475", "evidence": [ { "id": "0050475", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050475" } ], "weight": 0.0 }, { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:0050642", "name": "hypochromic microcytic anemia", "description": "A microcytic anemia characterized by paler than normal blood cells.", "url": "https://disease-ontology.org/term/DOID:0050642", "evidence": [ { "id": "0050642", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050642" } ], "weight": 0.0 }, { "disease_id": "DOID:0050685", "name": "small cell carcinoma", "description": "A carcinoma that is an undifferentiated neoplasm composed of primitive-appearing cells.", "url": "https://disease-ontology.org/term/DOID:0050685", "evidence": [ { "id": "0050685", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050685" } ], "weight": 0.0 }, { "disease_id": "DOID:0050697", "name": "chorioamnionitis", "description": "A placenta disease that is an inflammation of the fetal membranes (amnion and chorion) due to a bacterial infection.", "url": "https://disease-ontology.org/term/DOID:0050697", "evidence": [ { "id": "0050697", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050697" } ], "weight": 0.0 }, { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0050881", "name": "inclusion body myopathy with Paget disease of bone and frontotemporal dementia", "description": "A syndrome that is characterized by progressive proximal muscle weakness, steolytic bone lesions consistent with Paget disease, and frontotemporal dementia and has_material_basis_in mutation in the valosin containing protein.", "url": "https://disease-ontology.org/term/DOID:0050881", "evidence": [ { "id": "0050881", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050881" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:0051061", "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ], "weight": 0.0 }, { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0060643", "name": "primary sclerosing cholangitis", "description": "A sclerosing cholangitis characterized by fibroobliterative inflammation of the biliary tract, leading to cirrhosis and portal hypertension.", "url": "https://disease-ontology.org/term/DOID:0060643", "evidence": [ { "id": "0060643", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060643" } ], "weight": 0.0 }, { "disease_id": "DOID:0061092", "name": "immunodeficiency 127", "description": "A primary immunodeficiency disease that is characterized by increased susceptibility to recurrent pulmonary infection with Mycobacterium tuberculosis and that has_material_basis_in homozygous mutation in the TNF gene on chromosome 6p21.", "url": "https://disease-ontology.org/term/DOID:0061092", "evidence": [ { "id": "0061092", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061092" } ], "weight": 0.0 }, { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:0080162", "name": "lupus nephritis", "description": "A glomerulonephritis that is characterized by inflammation of the kidneys resulting from systemic lupus erythematosus.", "url": "https://disease-ontology.org/term/DOID:0080162", "evidence": [ { "id": "0080162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080162" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080600", "name": "COVID-19", "description": "A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum.", "url": "https://disease-ontology.org/term/DOID:0080600", "evidence": [ { "id": "0080600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080600" } ], "weight": 0.0 }, { "disease_id": "DOID:0080750", "name": "erythema nodosum", "description": "A panniculitis that is characterized by sudden onset of painful, erythematous, subcutaneous nodules mainly localized to the pretibial areas. Lesions are usually bilateral and symmetrical, ranging from 1 to 5 cm in diameter.", "url": "https://disease-ontology.org/term/DOID:0080750", "evidence": [ { "id": "0080750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080750" } ], "weight": 0.0 }, { "disease_id": "DOID:0081120", "name": "Graves ophthalmopathy", "description": "An autoimmune disease of eyes, ear, nose and throat that is characterized by upper eyelid retraction, lid lag, swelling, redness, conjunctivitis, and bulging eyes.", "url": "https://disease-ontology.org/term/DOID:0081120", "evidence": [ { "id": "0081120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081120" } ], "weight": 0.0 }, { "disease_id": "DOID:0110429", "name": "dilated cardiomyopathy 1H", "description": "A dilated cardiomyopathy that has_material_basis_in variation in the chromosome region 2q14-q22.", "url": "https://disease-ontology.org/term/DOID:0110429", "evidence": [ { "id": "0110429", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110429" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 }, { "disease_id": "DOID:1024", "name": "leprosy", "description": "A primary bacterial infectious disease that results_in infection located_in superficial peripheral nerves, located_in skin, located_in mucous membranes of the upper respiratory tract, located_in anterior chamber of the eyes, or located_in testes, has_material_basis_in Mycobacterium leprae, which is transmitted_by aerosol spread from infected nasal secretions to exposed nasal and oral mucosa. The infection has_symptom skin lesions, has_symptom sensory loss, has_symptom motor loss and has_symptom eye damage.", "url": "https://disease-ontology.org/term/DOID:1024", "evidence": [ { "id": "1024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1024" } ], "weight": 0.0 }, { "disease_id": "DOID:10241", "name": "thalassemia", "description": "A microcytic anemia characterized by decreased synthesis of one or more hemoglobin polypeptide chains.", "url": "https://disease-ontology.org/term/DOID:10241", "evidence": [ { "id": "10241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10241" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10325", "name": "silicosis", "description": "A pneumoconiosis that is an inflammation and scarring of the upper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles.", "url": "https://disease-ontology.org/term/DOID:10325", "evidence": [ { "id": "10325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10325" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1067", "name": "open-angle glaucoma", "description": "A glaucoma characterized by optic nerve damage resulting in progressive loss of visual field and increased pressure in the eye due to trabecular blockage.", "url": "https://disease-ontology.org/term/DOID:1067", "evidence": [ { "id": "1067", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1067" } ], "weight": 0.0 }, { "disease_id": "DOID:1070", "name": "primary open angle glaucoma", "description": "An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.", "url": "https://disease-ontology.org/term/DOID:1070", "evidence": [ { "id": "1070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1070" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain.", "url": "https://disease-ontology.org/term/DOID:10923", "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ], "weight": 0.0 }, { "disease_id": "DOID:10964", "name": "cholesteatoma of middle ear", "description": "", "url": "https://disease-ontology.org/term/DOID:10964", "evidence": [ { "id": "10964", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10964" } ], "weight": 0.0 }, { "disease_id": "DOID:11168", "name": "anogenital venereal wart", "description": "A viral infectious disease that results_in infection located_in skin of vagina, cervix, uterus, anus, penis, scrotum, mouth, or throat, has_material_basis_in human papillomaviruses (types 6 and 11), which are transmitted_by direct contact with the skin during oral, genital, or anal sex with an infected partner. The infection has_symptom anogenital warts.", "url": "https://disease-ontology.org/term/DOID:11168", "evidence": [ { "id": "11168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11168" } ], "weight": 0.0 }, { "disease_id": "DOID:1123", "name": "spondyloarthropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:1123", "evidence": [ { "id": "1123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1123" } ], "weight": 0.0 }, { "disease_id": "DOID:11247", "name": "disseminated intravascular coagulation", "description": "", "url": "https://disease-ontology.org/term/DOID:11247", "evidence": [ { "id": "11247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11247" } ], "weight": 0.0 }, { "disease_id": "DOID:11265", "name": "trachoma", "description": "A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea.", "url": "https://disease-ontology.org/term/DOID:11265", "evidence": [ { "id": "11265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11265" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:11396", "name": "pulmonary edema", "description": "A respiratory failure that is characterized by the accumulation of fluid in the lung tissues causing disturbance of the gas exchange that may lead to respiratory failure.", "url": "https://disease-ontology.org/term/DOID:11396", "evidence": [ { "id": "11396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11396" } ], "weight": 0.0 }, { "disease_id": "DOID:11650", "name": "bronchopulmonary dysplasia", "description": "A lung disease that is characterized by underdeveloped lungs in newborns that can be easily irritated or inflamed after birth resulting in damage to the alveoli of the lungs and bronchi. Most newborns who develop BPD are born more than 10 weeks before their due dates, weigh less than 2 pounds at birth, and have breathing problems.", "url": "https://disease-ontology.org/term/DOID:11650", "evidence": [ { "id": "11650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11650" } ], "weight": 0.0 }, { "disease_id": "DOID:11656", "name": "cicatricial pemphigoid", "description": "A pemphigoid that is characterized by skin lesions and scaring and located_in mucous membranes and located_in skin.", "url": "https://disease-ontology.org/term/DOID:11656", "evidence": [ { "id": "11656", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11656" } ], "weight": 0.0 }, { "disease_id": "DOID:11713", "name": "diabetic angiopathy", "description": "A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.", "url": "https://disease-ontology.org/term/DOID:11713", "evidence": [ { "id": "11713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11713" } ], "weight": 0.0 }, { "disease_id": "DOID:11758", "name": "iron deficiency anemia", "description": "A microcytic anemia that is characterized by pallor, fatigue, lightheadedness, and weakness and has_material_basis_in low total body iron causing impaired synthesis of red blood cells.", "url": "https://disease-ontology.org/term/DOID:11758", "evidence": [ { "id": "11758", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11758" } ], "weight": 0.0 }, { "disease_id": "DOID:11963", "name": "esophagitis", "description": "", "url": "https://disease-ontology.org/term/DOID:11963", "evidence": [ { "id": "11963", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11963" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12241", "name": "beta thalassemia", "description": "A thalassemia characterized by the reduced or absent synthesis of the beta globin chains of hemoglobin.", "url": "https://disease-ontology.org/term/DOID:12241", "evidence": [ { "id": "12241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12241" } ], "weight": 0.0 }, { "disease_id": "DOID:1227", "name": "neutropenia", "description": "", "url": "https://disease-ontology.org/term/DOID:1227", "evidence": [ { "id": "1227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1227" } ], "weight": 0.0 }, { "disease_id": "DOID:12297", "name": "Vogt-Koyanagi-Harada disease", "description": "An autoimmune disease that is caused by T helper cell mediated autoimmune attack of melanocytes resulting in inflammation of the inside of the eye, whitening of hair, skin pigment loss, and meningitis.", "url": "https://disease-ontology.org/term/DOID:12297", "evidence": [ { "id": "12297", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12297" } ], "weight": 0.0 }, { "disease_id": "DOID:12306", "name": "vitiligo", "description": "An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.", "url": "https://disease-ontology.org/term/DOID:12306", "evidence": [ { "id": "12306", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12306" } ], "weight": 0.0 }, { "disease_id": "DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.", "url": "https://disease-ontology.org/term/DOID:12361", "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:12449", "name": "aplastic anemia", "description": "A normocytic anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.", "url": "https://disease-ontology.org/term/DOID:12449", "evidence": [ { "id": "12449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12449" } ], "weight": 0.0 }, { "disease_id": "DOID:12549", "name": "hepatitis A", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus (Hepatovirus ahepa), which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:12549", "evidence": [ { "id": "12549", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12549" } ], "weight": 0.0 }, { "disease_id": "DOID:12662", "name": "paracoccidioidomycosis", "description": "A primary systemic mycosis that results_in systemic fungal infection located_in mucosa, located_in lymph nodes, located_in bone, located_in skin or located_in lungs, has_material_basis_in Paracoccidioides brasiliensis.", "url": "https://disease-ontology.org/term/DOID:12662", "evidence": [ { "id": "12662", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12662" } ], "weight": 0.0 }, { "disease_id": "DOID:1270", "name": "hereditary hemorrhagic telangiectasia", "description": "A vascular disease characterized by the presence of multiple arteriovenous malformations that lack intervening capillaries and result in direct connections between arteries and veins.", "url": "https://disease-ontology.org/term/DOID:1270", "evidence": [ { "id": "1270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1270" } ], "weight": 0.0 }, { "disease_id": "DOID:12732", "name": "intermediate uveitis", "description": "", "url": "https://disease-ontology.org/term/DOID:12732", "evidence": [ { "id": "12732", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12732" } ], "weight": 0.0 }, { "disease_id": "DOID:12783", "name": "migraine without aura", "description": "A migraine that is characterized by migraine headaches that are not accompanied by an aura.", "url": "https://disease-ontology.org/term/DOID:12783", "evidence": [ { "id": "12783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12783" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:12894", "name": "Sjogren's syndrome", "description": "An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.", "url": "https://disease-ontology.org/term/DOID:12894", "evidence": [ { "id": "12894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12894" } ], "weight": 0.0 }, { "disease_id": "DOID:12895", "name": "keratoconjunctivitis sicca", "description": "", "url": "https://disease-ontology.org/term/DOID:12895", "evidence": [ { "id": "12895", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12895" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:13088", "name": "periventricular leukomalacia", "description": "", "url": "https://disease-ontology.org/term/DOID:13088", "evidence": [ { "id": "13088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13088" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:13258", "name": "typhoid fever", "description": "A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. The infection has_symptom fever, has_symptom diarrhea, has_symptom prostration, has_symptom headache, has_symptom splenomegaly, has_symptom liver enlargement, has_symptom eruption of rose-colored spots, and has_symptom leukopenia.", "url": "https://disease-ontology.org/term/DOID:13258", "evidence": [ { "id": "13258", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13258" } ], "weight": 0.0 }, { "disease_id": "DOID:13276", "name": "Mycoplasma pneumoniae pneumonia", "description": "A bacterial pneumonia that is caused by the bacterial species Mycoplasma pneumoniae. The symptoms include chest pain, chills, dry cough which is not bloody, excessive sweating, fever, headache and sore throat.", "url": "https://disease-ontology.org/term/DOID:13276", "evidence": [ { "id": "13276", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13276" } ], "weight": 0.0 }, { "disease_id": "DOID:13378", "name": "Kawasaki disease", "description": "A lymphadenitis characterized by swelling of cervical lymph nodes in infants and young children and inflammation of medium-sized blood vessels and that symptoms of fever, congestion of ocular conjunctivae, reddening of lips, reddening of oral cavity, protuberance of tongue papillae and edema of extremities.", "url": "https://disease-ontology.org/term/DOID:13378", "evidence": [ { "id": "13378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13378" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:13452", "name": "scleritis", "description": "", "url": "https://disease-ontology.org/term/DOID:13452", "evidence": [ { "id": "13452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13452" } ], "weight": 0.0 }, { "disease_id": "DOID:13544", "name": "low tension glaucoma", "description": "An open-angle glaucoma characterized by increased intrinsic resistance to aqueous outflow without known secondary causes, an anatomically narrow anterior chamber angle, or elevated intraocular pressure compared to the average population. Normal tension glaucoma has_symptom progressive decreased vision and progressive loss of peripheral vision.", "url": "https://disease-ontology.org/term/DOID:13544", "evidence": [ { "id": "13544", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13544" } ], "weight": 0.0 }, { "disease_id": "DOID:13636", "name": "Fanconi anemia", "description": "A congenital hypoplastic anemia characterized by progressive pancytopenia with bone marrow failure, variable congenital malformations and predisposition to develop hematological or solid tumors. It is a result of a genetic defect in a cluster of proteins responsible for DNA repair.", "url": "https://disease-ontology.org/term/DOID:13636", "evidence": [ { "id": "13636", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13636" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:14067", "name": "Plasmodium falciparum malaria", "description": "A malaria described as a severe form of the disease caused by a parasite Plasmodium falciparum, which is marked by irrregular recurrence of paroxysms and prolonged or continuous fever.", "url": "https://disease-ontology.org/term/DOID:14067", "evidence": [ { "id": "14067", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14067" } ], "weight": 0.0 }, { "disease_id": "DOID:1407", "name": "anterior uveitis", "description": "", "url": "https://disease-ontology.org/term/DOID:1407", "evidence": [ { "id": "1407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1407" } ], "weight": 0.0 }, { "disease_id": "DOID:14453", "name": "farmer's lung", "description": "An extrinsic allergic alveolitis which is induced by the inhalation of spores (Aspergillus sp and thermophilic actinomycetes) in dust from moldy hay or straw. It is characterized by sudden onset, fever, cough, expectoration, and breathlessness.", "url": "https://disease-ontology.org/term/DOID:14453", "evidence": [ { "id": "14453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14453" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood.", "url": "https://disease-ontology.org/term/DOID:1588", "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1679", "name": "cystitis", "description": "A bladder disease that is characterized by inflammation of the bladder.", "url": "https://disease-ontology.org/term/DOID:1679", "evidence": [ { "id": "1679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1679" } ], "weight": 0.0 }, { "disease_id": "DOID:1712", "name": "aortic valve stenosis", "description": "An aortic valve disease that is characterized by narrowing of the heart's aortic valve opening.", "url": "https://disease-ontology.org/term/DOID:1712", "evidence": [ { "id": "1712", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1712" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:1926", "name": "Gaucher's disease", "description": "A sphingolipidosis characterized by deficiency of the enzyme glucocerebrosidase which results in the accumulation of harmful quantities of the glycolipid glucocerebroside throughout the body, especially within the bone marrow, spleen and liver.", "url": "https://disease-ontology.org/term/DOID:1926", "evidence": [ { "id": "1926", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1926" } ], "weight": 0.0 }, { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2048", "name": "autoimmune hepatitis", "description": "An autoimmune disease of gastrointestinal tract that results_in inflammation located_in liver caused by the body's immune system attacking the liver cells.", "url": "https://disease-ontology.org/term/DOID:2048", "evidence": [ { "id": "2048", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2048" } ], "weight": 0.0 }, { "disease_id": "DOID:2280", "name": "hidradenitis suppurativa", "description": "A hidradenitis that is characterized by chronic inflammation of the apocrine sweat glands, has_symptom painful nodules, abscesses, sinus tract formation, scarring, erythema, pruritis, and pain, and has_material_basis_in chronic inflammation of the apocrine sweat glands leading to recurrent folliculitis and an accompanying immune response that worsens inflammation.", "url": "https://disease-ontology.org/term/DOID:2280", "evidence": [ { "id": "2280", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2280" } ], "weight": 0.0 }, { "disease_id": "DOID:2352", "name": "hemochromatosis", "description": "A metal metabolism disorder characterized by the accumulation of iron in various organs of the body.", "url": "https://disease-ontology.org/term/DOID:2352", "evidence": [ { "id": "2352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2352" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2723", "name": "dermatitis", "description": "A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.", "url": "https://disease-ontology.org/term/DOID:2723", "evidence": [ { "id": "2723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2723" } ], "weight": 0.0 }, { "disease_id": "DOID:2755", "name": "Mycobacterium avium complex disease", "description": "A primary bacterial infectious disease that results_in infection, has_material_basis_in Mycobacterium avium complex (MAC), which is transmitted_by inhalation or transmitted_by ingestion of via the respiratory or gastrointestinal tract respectively. The bacteria cause disseminated infection in HIV infected people, while pulmonary disease in immunocompetent persons.", "url": "https://disease-ontology.org/term/DOID:2755", "evidence": [ { "id": "2755", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2755" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2917", "name": "cryoglobulinemia", "description": "A hypersensitivity reaction type IV disease that involves large amounts of cryoglobulins in the blood which become thick or gel-like in cold temperatures.", "url": "https://disease-ontology.org/term/DOID:2917", "evidence": [ { "id": "2917", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2917" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3310", "name": "atopic dermatitis", "description": "An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.", "url": "https://disease-ontology.org/term/DOID:3310", "evidence": [ { "id": "3310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3310" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 }, { "disease_id": "DOID:3458", "name": "breast adenocarcinoma", "description": "A breast carcinoma that originates in the milk ducts and/or lobules (glandular tissue) of the breast.", "url": "https://disease-ontology.org/term/DOID:3458", "evidence": [ { "id": "3458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3458" } ], "weight": 0.0 }, { "disease_id": "DOID:3492", "name": "mixed connective tissue disease", "description": "A collagen disease that is considered an overlap of three diseases, systemic lupus erythematosus, scleroderma, and polymyositis with very high titers of circulating antinuclear antibody to a ribonucleoprotein antigen.", "url": "https://disease-ontology.org/term/DOID:3492", "evidence": [ { "id": "3492", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3492" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:37", "name": "skin disease", "description": "An integumentary system disease that is located_in skin.", "url": "https://disease-ontology.org/term/DOID:37", "evidence": [ { "id": "37", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:37" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:4079", "name": "heart valve disease", "description": "A heart disease involving one or more of the four valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right).", "url": "https://disease-ontology.org/term/DOID:4079", "evidence": [ { "id": "4079", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4079" } ], "weight": 0.0 }, { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:4247", "name": "coronary restenosis", "description": "", "url": "https://disease-ontology.org/term/DOID:4247", "evidence": [ { "id": "4247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4247" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4398", "name": "pustulosis of palm and sole", "description": "", "url": "https://disease-ontology.org/term/DOID:4398", "evidence": [ { "id": "4398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4398" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.", "url": "https://disease-ontology.org/term/DOID:4483", "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 }, { "disease_id": "DOID:5614", "name": "eye disease", "description": "An eye and adnexa disease that is located_in the eye.", "url": "https://disease-ontology.org/term/DOID:5614", "evidence": [ { "id": "5614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5614" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:614", "name": "lymphopenia", "description": "A leukopenia that is the condition of having an abnormally low level of lymphocytes in the blood.", "url": "https://disease-ontology.org/term/DOID:614", "evidence": [ { "id": "614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:614" } ], "weight": 0.0 }, { "disease_id": "DOID:633", "name": "myositis", "description": "A myopathy characterized by muscle inflammation.", "url": "https://disease-ontology.org/term/DOID:633", "evidence": [ { "id": "633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:633" } ], "weight": 0.0 }, { "disease_id": "DOID:635", "name": "acquired immunodeficiency syndrome", "description": "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.", "url": "https://disease-ontology.org/term/DOID:635", "evidence": [ { "id": "635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:635" } ], "weight": 0.0 }, { "disease_id": "DOID:6364", "name": "migraine", "description": "A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing.", "url": "https://disease-ontology.org/term/DOID:6364", "evidence": [ { "id": "6364", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6364" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:6543", "name": "acne", "description": "A sebaceous gland disease characterized by areas of blackheads, whiteheads, pimples, greasy skin, and possibly scarring.", "url": "https://disease-ontology.org/term/DOID:6543", "evidence": [ { "id": "6543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6543" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8283", "name": "peritonitis", "description": "A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.", "url": "https://disease-ontology.org/term/DOID:8283", "evidence": [ { "id": "8283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8283" } ], "weight": 0.0 }, { "disease_id": "DOID:841", "name": "extrinsic allergic alveolitis", "description": "An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. Symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss.", "url": "https://disease-ontology.org/term/DOID:841", "evidence": [ { "id": "841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:841" } ], "weight": 0.0 }, { "disease_id": "DOID:8463", "name": "corneal ulcer", "description": "", "url": "https://disease-ontology.org/term/DOID:8463", "evidence": [ { "id": "8463", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8463" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 }, { "disease_id": "DOID:8505", "name": "dermatitis herpetiformis", "description": "", "url": "https://disease-ontology.org/term/DOID:8505", "evidence": [ { "id": "8505", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8505" } ], "weight": 0.0 }, { "disease_id": "DOID:8515", "name": "Cor pulmonale", "description": "A congestive heart failure that involves a failure of the right side of the heart and is characterized by an enlargement of the right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs.", "url": "https://disease-ontology.org/term/DOID:8515", "evidence": [ { "id": "8515", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8515" } ], "weight": 0.0 }, { "disease_id": "DOID:8536", "name": "herpes zoster", "description": "A viral infectious disease that results_in infection located_in nerve fiber, has_material_basis_in Human herpesvirus 3 (Varicellovirus humanalpha3), which reactivates after appearing as chickenpox in childhood. The virus is transmitted_by direct contact with the rash, which can develop into chickenpox in newly-infected individuals. The infection has_symptom rash which is followed by blisters, has_symptom headache, has_symptom fever, has_symptom malaise, has_symptom itching, has_symptom burning pain, and has_symptom paresthesia.", "url": "https://disease-ontology.org/term/DOID:8536", "evidence": [ { "id": "8536", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8536" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:8677", "name": "perinatal necrotizing enterocolitis", "description": "", "url": "https://disease-ontology.org/term/DOID:8677", "evidence": [ { "id": "8677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8677" } ], "weight": 0.0 }, { "disease_id": "DOID:8725", "name": "vascular dementia", "description": "A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.", "url": "https://disease-ontology.org/term/DOID:8725", "evidence": [ { "id": "8725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8725" } ], "weight": 0.0 }, { "disease_id": "DOID:874", "name": "bacterial pneumonia", "description": "A pneumonia involving inflammation of the lungs caused by bacteria.", "url": "https://disease-ontology.org/term/DOID:874", "evidence": [ { "id": "874", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:874" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9008", "name": "psoriatic arthritis", "description": "An arthritis that is characterized by joint inflammation that usually occurs in combination with psoriasis.", "url": "https://disease-ontology.org/term/DOID:9008", "evidence": [ { "id": "9008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9008" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9120", "name": "amyloidosis", "description": "A disease of metabolism that is characterized by extracellular tissue deposition of mis-folded amyloid fibrils built up by twisted protofilaments, deposited in the spaces between the cells of vital organs, causing disruption of organ tissue structure and function. These deposits may result in a wide range of clinical manifestations depending upon their type, location, and the amount of deposition.", "url": "https://disease-ontology.org/term/DOID:9120", "evidence": [ { "id": "9120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9120" } ], "weight": 0.0 }, { "disease_id": "DOID:9146", "name": "visceral leishmaniasis", "description": "A leishmaniasis that is the most severe form of the disease caused by protozoan parasites of the Leishmania genus, resulting in the infection of the internal organs such as liver, spleen and bone marrow. The symptoms include fever, weight loss, and an enlarged spleen and liver.", "url": "https://disease-ontology.org/term/DOID:9146", "evidence": [ { "id": "9146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9146" } ], "weight": 0.0 }, { "disease_id": "DOID:9155", "name": "mucocutaneous leishmaniasis", "description": "A leishmaniasis that involves a chronic inflammatory process involving the nasal, pharyngeal, and laryngeal mucosa, which can lead to extensive tissue destruction, caused by protozoan parasites belonging to the genus Leishmania. The infection is characterized by granulomatous lesion which can destroy upper respiratory tract mucosa.", "url": "https://disease-ontology.org/term/DOID:9155", "evidence": [ { "id": "9155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9155" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9563", "name": "bronchiectasis", "description": "A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances.", "url": "https://disease-ontology.org/term/DOID:9563", "evidence": [ { "id": "9563", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9563" } ], "weight": 0.0 }, { "disease_id": "DOID:9719", "name": "neovascular inflammatory vitreoretinopathy", "description": "A retinal and vitreous disease characterized by ocular inflammation, vascular dropout, large spots of hyperpigmentation, neovascularization of the peripheral and posterior retina, vitreous hemorrhage, and retinal detachment that has_material_basis_in heterozygous mutation in the CAPN5 gene on chromosome 11q13.5.", "url": "https://disease-ontology.org/term/DOID:9719", "evidence": [ { "id": "9719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9719" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" }, { "name": "positive regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001238", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" }, { "name": "tumor necrosis factor receptor binding", "id": "GO:0005164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005164", "evidence": [ { "database": "UniProtKB", "id": "Q4W898", "url": "https://www.uniprot.org/uniprotkb/Q4W898" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q502B3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q502B3", "url": "https://www.uniprot.org/uniprotkb/Q502B3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 491, "chemical_mass": 54876.0, "gene_names": "b3galnt2;b3galnt2;zgc:112351", "protein_name": "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2", "disease": [ { "disease_id": "DOID:0111230", "name": "congenital muscular dystrophy-dystroglycanopathy type A11", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in B3GALNT2 on 1q42.3.", "url": "https://disease-ontology.org/term/DOID:0111230", "evidence": [ { "id": "0111230", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111230" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q502B3", "url": "https://www.uniprot.org/uniprotkb/Q502B3" } ], "pmid": "" }, { "name": "acetylgalactosaminyltransferase activity", "id": "GO:0008376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008376", "evidence": [ { "database": "UniProtKB", "id": "Q502B3", "url": "https://www.uniprot.org/uniprotkb/Q502B3" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q502B3", "url": "https://www.uniprot.org/uniprotkb/Q502B3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q502B3", "url": "https://www.uniprot.org/uniprotkb/Q502B3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "Q502B3", "url": "https://www.uniprot.org/uniprotkb/Q502B3" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "Q502B3", "url": "https://www.uniprot.org/uniprotkb/Q502B3" } ], "pmid": "" }, { "name": "muscle cell development", "id": "GO:0055001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055001", "evidence": [ { "database": "UniProtKB", "id": "Q502B3", "url": "https://www.uniprot.org/uniprotkb/Q502B3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q502B3-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Asn167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 167, "start_aa": "Asn", "end_pos": 167, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn167", "evidence": [ { "id": "Q502B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q502B3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q502B3-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Asn230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 230, "start_aa": "Asn", "end_pos": 230, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn230", "evidence": [ { "id": "Q502B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q502B3#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q502I9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 848, "chemical_mass": 93657.0, "gene_names": "fcho2;cb304;sb:cb304;si:ch211-195c22.1;wu:fa01a02;zgc:112167", "protein_name": "F-BAR domain only protein 2", "disease": [ { "disease_id": "DOID:0060894", "name": "early-onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms earlier than typically seen, usually prior to 50 years of age.", "url": "https://disease-ontology.org/term/DOID:0060894", "evidence": [ { "id": "0060894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060894" } ], "weight": 0.0 } ], "biological_process": [ { "name": "membrane invagination", "id": "GO:0010324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010324", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "clathrin coat assembly", "id": "GO:0048268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048268", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "convergent extension involved in axis elongation", "id": "GO:0060028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060028", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q502I9-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Thr407", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 407, "start_aa": "Thr", "end_pos": 407, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr407", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q502I9-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Ser405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ] } ] }, { "uniprot_canonical_ac": "Q502I9-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Ser417", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q502I9", "url": "https://www.uniprot.org/uniprotkb/Q502I9" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q503I8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 644, "chemical_mass": 72489.0, "gene_names": "ngly1;im:6895151;ngly1;zgc:110561", "protein_name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "disease": [ { "disease_id": "DOID:0060728", "name": "congenital disorder of deglycosylation 1", "description": "A carbohydrate metabolic disorder that is characterized by global developmental delay, hypotonia, abnormal involuntary movements, and alacrima or poor tear production and that has_material_basis_in homozygous or compound heterozygous mutation in the NGLY1 gene on chromosome 3p24.", "url": "https://disease-ontology.org/term/DOID:0060728", "evidence": [ { "id": "0060728", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060728" } ], "weight": 0.0 }, { "disease_id": "DOID:0060991", "name": "congenital disorder of deglycosylation", "description": "A carbohydrate metabolic disorder that is charactized mutations resulting in malfunction impacting the addition of glycans to proteins.", "url": "https://disease-ontology.org/term/DOID:0060991", "evidence": [ { "id": "0060991", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060991" } ], "weight": 0.0 } ], "biological_process": [ { "name": "peripheral nervous system neuron axonogenesis", "id": "GO:0048936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048936", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "regulation of protein catabolic process", "id": "GO:0042176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042176", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "glycoprotein catabolic process", "id": "GO:0006516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006516", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "regulation of protein folding", "id": "GO:1903332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903332", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity", "id": "GO:0000224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000224", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q503I8", "url": "https://www.uniprot.org/uniprotkb/Q503I8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q503I8-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q503V1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 253, "chemical_mass": 27905.0, "gene_names": "cybrd1;cybrd1;im:6900453;zgc:110065", "protein_name": "Plasma membrane ascorbate-dependent reductase CYBRD1", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" }, { "name": "transmembrane monodehydroascorbate reductase activity", "id": "GO:0140575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140575", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" }, { "name": "transmembrane ascorbate ferrireductase activity", "id": "GO:0140571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140571", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" } ], "biological_process": [ { "name": "multicellular organismal-level iron ion homeostasis", "id": "GO:0060586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060586", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" }, { "name": "ascorbate homeostasis", "id": "GO:0140576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140576", "evidence": [ { "database": "UniProtKB", "id": "Q503V1", "url": "https://www.uniprot.org/uniprotkb/Q503V1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q52PJ5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 567, "chemical_mass": 61544.0, "gene_names": "dpysl3;CRMP-4;dpysl3", "protein_name": "Dihydropyrimidinase-related protein 3", "disease": [], "biological_process": [ { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" }, { "name": "peripheral nervous system neuron axonogenesis", "id": "GO:0048936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048936", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" }, { "name": "actin crosslink formation", "id": "GO:0051764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051764", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides", "id": "GO:0016812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016812", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" }, { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds", "id": "GO:0016810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016810", "evidence": [ { "database": "UniProtKB", "id": "Q52PJ5", "url": "https://www.uniprot.org/uniprotkb/Q52PJ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q52PJ5-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 241, "start_aa": "Thr", "end_pos": 241, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr241", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q566V9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 142, "chemical_mass": 16488.0, "gene_names": "ecrg4a;ecrg4a;zgc:112443", "protein_name": "Augurin-A", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" }, { "name": "cellular senescence", "id": "GO:0090398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090398", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" }, { "name": "G1 to G0 transition", "id": "GO:0070314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070314", "evidence": [ { "database": "UniProtKB", "id": "Q566V9", "url": "https://www.uniprot.org/uniprotkb/Q566V9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q566X8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 369, "chemical_mass": 40643.0, "gene_names": "dmbx1b;dmbx1b;mbx2;zgc:112395", "protein_name": "Diencephalon/mesencephalon homeobox protein 1-B", "disease": [], "biological_process": [ { "name": "regulation of neural retina development", "id": "GO:0061074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061074", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" }, { "name": "midbrain development", "id": "GO:0030901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030901", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q566X8", "url": "https://www.uniprot.org/uniprotkb/Q566X8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q567B1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 301, "chemical_mass": 33486.0, "gene_names": "yod1;fe01a10;wu:fe01a10;yod1;zgc:112182", "protein_name": "Ubiquitin thioesterase OTU1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "protein K29-linked deubiquitination", "id": "GO:0035523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035523", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "protein K27-linked deubiquitination", "id": "GO:1990167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990167", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "protein K33-linked deubiquitination", "id": "GO:1990168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990168", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "Q567B1", "url": "https://www.uniprot.org/uniprotkb/Q567B1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q567B1-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q568F6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q568F6", "url": "https://www.uniprot.org/uniprotkb/Q568F6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 455, "chemical_mass": 49720.0, "gene_names": "adss2;AdSS 2;adss2;adss;zgc:110327", "protein_name": "Adenylosuccinate synthetase isozyme 2", "disease": [ { "disease_id": "DOID:1115", "name": "sarcoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm.", "url": "https://disease-ontology.org/term/DOID:1115", "evidence": [ { "id": "1115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1115" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q568F6", "url": "https://www.uniprot.org/uniprotkb/Q568F6" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q568F6", "url": "https://www.uniprot.org/uniprotkb/Q568F6" } ], "pmid": "" }, { "name": "adenylosuccinate synthase activity", "id": "GO:0004019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004019", "evidence": [ { "database": "UniProtKB", "id": "Q568F6", "url": "https://www.uniprot.org/uniprotkb/Q568F6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q568F6", "url": "https://www.uniprot.org/uniprotkb/Q568F6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q568F6", "url": "https://www.uniprot.org/uniprotkb/Q568F6" } ], "pmid": "" } ], "biological_process": [ { "name": "IMP metabolic process", "id": "GO:0046040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046040", "evidence": [ { "database": "UniProtKB", "id": "Q568F6", "url": "https://www.uniprot.org/uniprotkb/Q568F6" } ], "pmid": "" }, { "name": "'de novo' AMP biosynthetic process", "id": "GO:0044208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044208", "evidence": [ { "database": "UniProtKB", "id": "Q568F6", "url": "https://www.uniprot.org/uniprotkb/Q568F6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q568I2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q568I2", "url": "https://www.uniprot.org/uniprotkb/Q568I2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 266, "chemical_mass": 30908.0, "gene_names": "acer1;asah3;zgc:110285", "protein_name": "Alkaline ceramidase 1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q568I2", "url": "https://www.uniprot.org/uniprotkb/Q568I2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q568I2", "url": "https://www.uniprot.org/uniprotkb/Q568I2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q568I2", "url": "https://www.uniprot.org/uniprotkb/Q568I2" } ], "pmid": "" }, { "name": "N-acylsphingosine amidohydrolase activity", "id": "GO:0017040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017040", "evidence": [ { "database": "UniProtKB", "id": "Q568I2", "url": "https://www.uniprot.org/uniprotkb/Q568I2" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingosine biosynthetic process", "id": "GO:0046512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046512", "evidence": [ { "database": "UniProtKB", "id": "Q568I2", "url": "https://www.uniprot.org/uniprotkb/Q568I2" } ], "pmid": "" }, { "name": "ceramide catabolic process", "id": "GO:0046514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046514", "evidence": [ { "database": "UniProtKB", "id": "Q568I2", "url": "https://www.uniprot.org/uniprotkb/Q568I2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q568K9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q568K9", "url": "https://www.uniprot.org/uniprotkb/Q568K9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 341, "chemical_mass": 40542.0, "gene_names": "fam50a;db03h09;fam50a;mg:db03h09;wu:ft29b08;zgc:110236", "protein_name": "Protein FAM50A", "disease": [ { "disease_id": "DOID:0050764", "name": "Armfield syndrome", "description": "A syndromic X-linked intellectual disability characterized by intellectual disability, short stature, seizures, and small hands and feet and in some cases cleft palate or cataracts/glaucoma that has_material_basis_in variation in the chromosomal region Xq28.", "url": "https://disease-ontology.org/term/DOID:0050764", "evidence": [ { "id": "0050764", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050764" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q568K9", "url": "https://www.uniprot.org/uniprotkb/Q568K9" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q568K9", "url": "https://www.uniprot.org/uniprotkb/Q568K9" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q568K9", "url": "https://www.uniprot.org/uniprotkb/Q568K9" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q568K9", "url": "https://www.uniprot.org/uniprotkb/Q568K9" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q568K9", "url": "https://www.uniprot.org/uniprotkb/Q568K9" } ], "pmid": "" }, { "name": "embryonic cranial skeleton morphogenesis", "id": "GO:0048701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048701", "evidence": [ { "database": "UniProtKB", "id": "Q568K9", "url": "https://www.uniprot.org/uniprotkb/Q568K9" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "Q568K9", "url": "https://www.uniprot.org/uniprotkb/Q568K9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q56UJ5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q56UJ5", "url": "https://www.uniprot.org/uniprotkb/Q56UJ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 413, "chemical_mass": 48910.0, "gene_names": "hs6st1a;6-ost-1a;HS6ST-1;hs6st1a;hs6st1;zgc:110038", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-A", "disease": [ { "disease_id": "DOID:0090075", "name": "hypogonadotropic hypogonadism 15 with or without anosmia", "description": "A hypogonadotropic hypogonadism that has_material_basis_in mutation in the HS6ST1 gene on chromosome 2q14, sometimes in association with mutations in other genes.", "url": "https://disease-ontology.org/term/DOID:0090075", "evidence": [ { "id": "0090075", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090075" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q56UJ5", "url": "https://www.uniprot.org/uniprotkb/Q56UJ5" } ], "pmid": "" } ], "biological_process": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "Q56UJ5", "url": "https://www.uniprot.org/uniprotkb/Q56UJ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparan sulfate 6-sulfotransferase activity", "id": "GO:0017095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017095", "evidence": [ { "database": "UniProtKB", "id": "Q56UJ5", "url": "https://www.uniprot.org/uniprotkb/Q56UJ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q56UJ5-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Thr215", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q56UJ5-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Asn262", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 262, "start_aa": "Asn", "end_pos": 262, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn262", "evidence": [ { "id": "Q56UJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q56UJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q56UJ5-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Asn318", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 318, "start_aa": "Asn", "end_pos": 318, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn318", "evidence": [ { "id": "Q56UJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q56UJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q56UJ5-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Asn329", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 329, "start_aa": "Asn", "end_pos": 329, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn329", "evidence": [ { "id": "Q56UJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q56UJ5#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q58EC8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 198, "chemical_mass": 21736.0, "gene_names": "rnf152;zgc:110537", "protein_name": "E3 ubiquitin-protein ligase rnf152", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "hindbrain development", "id": "GO:0030902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030902", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "midbrain-hindbrain boundary development", "id": "GO:0030917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030917", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "eye development", "id": "GO:0001654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001654", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "Q58EC8", "url": "https://www.uniprot.org/uniprotkb/Q58EC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q58ED9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 178, "chemical_mass": 20358.0, "gene_names": "naa20;im:7150897;naa20;nat5;zgc:110819", "protein_name": "N-alpha-acetyltransferase 20", "disease": [ { "disease_id": "DOID:0081233", "name": "autosomal recessive intellectual developmental disorder 73", "description": "An autosomal recessive intellectual developmental disorder that is characterized by global developmental delay with hypotonia and mildly delayed walking, impaired intellectual development with poor or absent speech, and mildly dysmorphic features and that has_material_basis_in homozygous mutation in the NAA20 gene on chromosome 20p11.", "url": "https://disease-ontology.org/term/DOID:0081233", "evidence": [ { "id": "0081233", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081233" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" }, { "name": "NatB complex", "id": "GO:0031416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031416", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" }, { "name": "N-terminal protein amino acid acetylation", "id": "GO:0006474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006474", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" }, { "name": "N-terminal peptidyl-glutamic acid acetylation", "id": "GO:0018002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018002", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" }, { "name": "N-terminal peptidyl-aspartic acid acetylation", "id": "GO:0017190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017190", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" }, { "name": "N-terminal peptidyl-glutamine acetylation", "id": "GO:0017192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017192", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-N-terminal amino-acid acetyltransferase activity", "id": "GO:0004596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004596", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" }, { "name": "protein N-terminal-methionine acetyltransferase activity", "id": "GO:0120518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120518", "evidence": [ { "database": "UniProtKB", "id": "Q58ED9", "url": "https://www.uniprot.org/uniprotkb/Q58ED9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q58EG3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 574, "chemical_mass": 63995.0, "gene_names": "nectin3b;nectin3;fj99c02;nectin3b;nectin3;pvrl3b;pvrl3l;si:dkey-62a13.5;wu:fj99c02;zgc:113035", "protein_name": "Nectin-3-like protein", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "pmid": "" } ], "biological_process": [ { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion mediator activity", "id": "GO:0098631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098631", "evidence": [ { "database": "UniProtKB", "id": "Q58EG3", "url": "https://www.uniprot.org/uniprotkb/Q58EG3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q58EG3-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Asn167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 167, "start_aa": "Asn", "end_pos": 167, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn167", "evidence": [ { "id": "Q58EG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58EG3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q58EG3-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Asn204", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 204, "start_aa": "Asn", "end_pos": 204, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn204", "evidence": [ { "id": "Q58EG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58EG3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q58EG3-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Asn301", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 301, "start_aa": "Asn", "end_pos": 301, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn301", "evidence": [ { "id": "Q58EG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58EG3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q58EG3-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Asn313", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 313, "start_aa": "Asn", "end_pos": 313, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn313", "evidence": [ { "id": "Q58EG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58EG3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q58EG3-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Asn52", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 52, "start_aa": "Asn", "end_pos": 52, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn52", "evidence": [ { "id": "Q58EG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58EG3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q58EG3-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Asn64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 64, "start_aa": "Asn", "end_pos": 64, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn64", "evidence": [ { "id": "Q58EG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58EG3#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q58EM4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 448, "chemical_mass": 51776.0, "gene_names": "dcph1;CH73-109I14.2;armt1;dcph1;zgc:110816", "protein_name": "Damage-control phosphatase 1", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "pmid": "" }, { "name": "protein carboxyl O-methyltransferase activity", "id": "GO:0051998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051998", "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "pmid": "" }, { "name": "fructose 6-phosphate aldolase activity", "id": "GO:0097023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097023", "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "pmid": "" }, { "name": "fructose-1-phosphatase activity", "id": "GO:0103026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0103026", "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q58EM4", "url": "https://www.uniprot.org/uniprotkb/Q58EM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5BKW9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5BKW9", "url": "https://www.uniprot.org/uniprotkb/Q5BKW9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 310, "chemical_mass": 32929.0, "gene_names": "asrgl1;asrgl1;zgc:103568", "protein_name": "Isoaspartyl peptidase/L-asparaginase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5BKW9", "url": "https://www.uniprot.org/uniprotkb/Q5BKW9" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "Q5BKW9", "url": "https://www.uniprot.org/uniprotkb/Q5BKW9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q5BKW9", "url": "https://www.uniprot.org/uniprotkb/Q5BKW9" } ], "pmid": "" }, { "name": "L-asparagine catabolic process via L-aspartate", "id": "GO:0033345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033345", "evidence": [ { "database": "UniProtKB", "id": "Q5BKW9", "url": "https://www.uniprot.org/uniprotkb/Q5BKW9" } ], "pmid": "" } ], "molecular_function": [ { "name": "asparaginase activity", "id": "GO:0004067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004067", "evidence": [ { "database": "UniProtKB", "id": "Q5BKW9", "url": "https://www.uniprot.org/uniprotkb/Q5BKW9" } ], "pmid": "" }, { "name": "beta-aspartyl-peptidase activity", "id": "GO:0008798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008798", "evidence": [ { "database": "UniProtKB", "id": "Q5BKW9", "url": "https://www.uniprot.org/uniprotkb/Q5BKW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5D018-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 174, "chemical_mass": 19881.0, "gene_names": "rbm8a;fb34f03;rbm8a;rbm8;wu:fb34f03;zgc:110525", "protein_name": "RNA-binding protein 8A", "disease": [ { "disease_id": "DOID:14699", "name": "thrombocytopenia-absent radius syndrome", "description": "A chromosomal deletion syndrome that is characterized by absence of the radius bone and platelet deficiency and bilateral absence of the radii with the presence of both thumbs and generally transient thrombocytopenia (less than 50 platelets/nL) and that has_material_basis_in compound heterozygosity for a rare null mutation involving the RBM8A gene on chromosome 1q12 on 1 allele and 1 of 2 low-frequency noncoding single-nucleotide polymorphisms in RBM8A on the other.", "url": "https://disease-ontology.org/term/DOID:14699", "evidence": [ { "id": "14699", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14699" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q5D018", "url": "https://www.uniprot.org/uniprotkb/Q5D018" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5FBD1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 608, "chemical_mass": 68586.0, "gene_names": "araf;araf;sb:eu994;wu:fk45h07;zgc:92074", "protein_name": "non-specific serine/threonine protein kinase", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of nodal signaling pathway", "id": "GO:1900108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900108", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" }, { "name": "negative regulation of SMAD protein signal transduction", "id": "GO:0060392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060392", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5FBD1", "url": "https://www.uniprot.org/uniprotkb/Q5FBD1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5FBD1-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Thr346", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 346, "start_aa": "Thr", "end_pos": 346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr346", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5I0F6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 379, "chemical_mass": 43111.0, "gene_names": "prkar1aa;im:7047729;prkar1aa;prkar1a;zgc:92515", "protein_name": "cAMP-dependent protein kinase type I-alpha regulatory subunit", "disease": [ { "disease_id": "DOID:0050471", "name": "Carney complex", "description": "A syndrome characterized by myxomas, spotty pigmentation of the skin and endocrine overactivity.", "url": "https://disease-ontology.org/term/DOID:0050471", "evidence": [ { "id": "0050471", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050471" } ], "weight": 0.0 }, { "disease_id": "DOID:0060280", "name": "primary pigmented nodular adrenocortical disease", "description": "An adrenal cortex disease characterized by small to normal sized adrenal glands containing multiple small cortical pigmented nodules.", "url": "https://disease-ontology.org/term/DOID:0060280", "evidence": [ { "id": "0060280", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060280" } ], "weight": 0.0 }, { "disease_id": "DOID:0070546", "name": "primary pigmented nodular adrenocortical disease 1", "description": "A primary pigmented nodular adrenocortical disease that has_material_basis_in heterozygous mutation in the PRKAR1A gene on chromosome 17q24.2.", "url": "https://disease-ontology.org/term/DOID:0070546", "evidence": [ { "id": "0070546", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070546" } ], "weight": 0.0 }, { "disease_id": "DOID:14669", "name": "acrodysostosis", "description": "A dysostosis that results_in shortening of interphalangeal joints located_in hand or located_in foot along with mental deficiency.", "url": "https://disease-ontology.org/term/DOID:14669", "evidence": [ { "id": "14669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14669" } ], "weight": 0.0 }, { "disease_id": "DOID:3962", "name": "follicular thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that has_material_basis_in follicular cells.", "url": "https://disease-ontology.org/term/DOID:3962", "evidence": [ { "id": "3962", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3962" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase A catalytic subunit binding", "id": "GO:0034236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034236", "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "pmid": "" }, { "name": "cAMP-dependent protein kinase inhibitor activity", "id": "GO:0004862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004862", "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "pmid": "" }, { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "pmid": "" }, { "name": "cAMP-dependent protein kinase complex", "id": "GO:0005952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005952", "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "pmid": "" } ], "biological_process": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "Q5I0F6", "url": "https://www.uniprot.org/uniprotkb/Q5I0F6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5I2W8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 818, "chemical_mass": 89407.0, "gene_names": "nbn;Nbs1;im:6911679;nbn;nbs1;zgc:194152", "protein_name": "Nibrin", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12449", "name": "aplastic anemia", "description": "A normocytic anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.", "url": "https://disease-ontology.org/term/DOID:12449", "evidence": [ { "id": "12449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12449" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1993", "name": "rectum cancer", "description": "A colorectal cancer that is located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:1993", "evidence": [ { "id": "1993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1993" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:5603", "name": "T-cell acute lymphoblastic leukemia", "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood.", "url": "https://disease-ontology.org/term/DOID:5603", "evidence": [ { "id": "5603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5603" } ], "weight": 0.0 }, { "disease_id": "DOID:7400", "name": "Nijmegen breakage syndrome", "description": "A syndrome characterized by chromosomal instability, microcephaly, growth retardation, immunodeficiency, cellular hypersensitivity to X-rays, and predisposition to cancer that has_material_basis_in homozygous or compound heterozygous mutation in NBN on chromosome 8q21.3.", "url": "https://disease-ontology.org/term/DOID:7400", "evidence": [ { "id": "7400", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7400" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "biological_process": [ { "name": "protein localization to site of double-strand break", "id": "GO:1990166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990166", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "telomere maintenance in response to DNA damage", "id": "GO:0043247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043247", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "protection from non-homologous end joining at telomere", "id": "GO:0031848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031848", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "DNA double-strand break processing", "id": "GO:0000729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000729", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "R-loop processing", "id": "GO:0062176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062176", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" } ], "molecular_function": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "phosphorylation-dependent protein binding", "id": "GO:0140031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140031", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" } ], "cellular_component": [ { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" }, { "name": "Mre11 complex", "id": "GO:0030870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030870", "evidence": [ { "database": "UniProtKB", "id": "Q5I2W8", "url": "https://www.uniprot.org/uniprotkb/Q5I2W8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5I2W8-1", "start_pos": "549", "end_pos": "549", "site_lbl": "Thr549", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 549, "start_aa": "Thr", "end_pos": 549, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr549", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5IGR6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 737, "chemical_mass": 85389.0, "gene_names": "ext1c;fa93b07;wu:fa93b07;zgc:136662", "protein_name": "Exostosin-1c", "disease": [ { "disease_id": "DOID:206", "name": "hereditary multiple exostoses", "description": "An exostosis that has_material_basis_in a mutation on the genes EXT1, EXT2 and EXT3 which results in multiple bony spurs throughout a child's growth.", "url": "https://disease-ontology.org/term/DOID:206", "evidence": [ { "id": "206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:206" } ], "weight": 0.0 }, { "disease_id": "DOID:2994", "name": "germ cell cancer", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from germ cells.", "url": "https://disease-ontology.org/term/DOID:2994", "evidence": [ { "id": "2994", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2994" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" }, { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0050508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050508", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" }, { "name": "N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity", "id": "GO:0050509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050509", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" } ], "biological_process": [ { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR6", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5IGR6-1", "start_pos": "194", "end_pos": "194", "site_lbl": "Asn194", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 194, "start_aa": "Asn", "end_pos": 194, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn194", "evidence": [ { "id": "Q5IGR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5IGR6-1", "start_pos": "322", "end_pos": "322", "site_lbl": "Asn322", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 322, "start_aa": "Asn", "end_pos": 322, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn322", "evidence": [ { "id": "Q5IGR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5IGR7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 741, "chemical_mass": 85121.0, "gene_names": "ext1b;LOC141377498;LOC141381663", "protein_name": "Exostosin-1b", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:206", "name": "hereditary multiple exostoses", "description": "An exostosis that has_material_basis_in a mutation on the genes EXT1, EXT2 and EXT3 which results in multiple bony spurs throughout a child's growth.", "url": "https://disease-ontology.org/term/DOID:206", "evidence": [ { "id": "206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:206" } ], "weight": 0.0 }, { "disease_id": "DOID:2994", "name": "germ cell cancer", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from germ cells.", "url": "https://disease-ontology.org/term/DOID:2994", "evidence": [ { "id": "2994", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2994" } ], "weight": 0.0 }, { "disease_id": "DOID:3371", "name": "chondrosarcoma", "description": "A bone sarcoma that has_material_basis_in cells derived from transformed cells that produce cartilage.", "url": "https://disease-ontology.org/term/DOID:3371", "evidence": [ { "id": "3371", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3371" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" }, { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0050508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050508", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" }, { "name": "N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity", "id": "GO:0050509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050509", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" } ], "biological_process": [ { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR7", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5IGR7-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Asn325", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "Q5IGR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5IGR7-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Asn84", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 84, "start_aa": "Asn", "end_pos": 84, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn84", "evidence": [ { "id": "Q5IGR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5IGR8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 730, "chemical_mass": 84618.0, "gene_names": "ext1a;fd07d06;wu:fd07d06", "protein_name": "Exostosin-1a", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:206", "name": "hereditary multiple exostoses", "description": "An exostosis that has_material_basis_in a mutation on the genes EXT1, EXT2 and EXT3 which results in multiple bony spurs throughout a child's growth.", "url": "https://disease-ontology.org/term/DOID:206", "evidence": [ { "id": "206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:206" } ], "weight": 0.0 }, { "disease_id": "DOID:2994", "name": "germ cell cancer", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from germ cells.", "url": "https://disease-ontology.org/term/DOID:2994", "evidence": [ { "id": "2994", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2994" } ], "weight": 0.0 }, { "disease_id": "DOID:3371", "name": "chondrosarcoma", "description": "A bone sarcoma that has_material_basis_in cells derived from transformed cells that produce cartilage.", "url": "https://disease-ontology.org/term/DOID:3371", "evidence": [ { "id": "3371", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3371" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" }, { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0050508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050508", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" }, { "name": "N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity", "id": "GO:0050509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050509", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" } ], "biological_process": [ { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "Q5IGR8", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5IGR8-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Asn314", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 314, "start_aa": "Asn", "end_pos": 314, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn314", "evidence": [ { "id": "Q5IGR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5IHX7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5IHX7", "url": "https://www.uniprot.org/uniprotkb/Q5IHX7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 146, "chemical_mass": 16458.0, "gene_names": "ptges;mpges;ptges;zgc:110052", "protein_name": "Prostaglandin E synthase", "disease": [ { "disease_id": "DOID:0060074", "name": "ductal carcinoma in situ", "description": "A breast carcinoma in situ that is characterized by being non-invasive, not having spread outside of the duct into the surrounding breast tissue, has_material_basis_in abnormally proliferating cells, derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:0060074", "evidence": [ { "id": "0060074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060074" } ], "weight": 0.0 }, { "disease_id": "DOID:11624", "name": "penile benign neoplasm", "description": "", "url": "https://disease-ontology.org/term/DOID:11624", "evidence": [ { "id": "11624", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11624" } ], "weight": 0.0 }, { "disease_id": "DOID:13976", "name": "peptic esophagitis", "description": "", "url": "https://disease-ontology.org/term/DOID:13976", "evidence": [ { "id": "13976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13976" } ], "weight": 0.0 }, { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:2615", "name": "papilloma", "description": "A cell type benign neoplam that is composed of epithelial tissue on papillae of vascularized connective tissue.", "url": "https://disease-ontology.org/term/DOID:2615", "evidence": [ { "id": "2615", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2615" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:2870", "name": "endometrial adenocarcinoma", "description": "An endometrial carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2870", "evidence": [ { "id": "2870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2870" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:8719", "name": "in situ carcinoma", "description": "A carcinoma that is an early development defined by the absence of invasion of surrounding tissues.", "url": "https://disease-ontology.org/term/DOID:8719", "evidence": [ { "id": "8719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8719" } ], "weight": 0.0 }, { "disease_id": "DOID:9206", "name": "Barrett's esophagus", "description": "An esophageal disease characterized by a change of normal esophageal squamous epithelium to a columnar and intestinal-type epithelium.", "url": "https://disease-ontology.org/term/DOID:9206", "evidence": [ { "id": "9206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9206" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "Q5IHX7", "url": "https://www.uniprot.org/uniprotkb/Q5IHX7" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q5IHX7", "url": "https://www.uniprot.org/uniprotkb/Q5IHX7" } ], "pmid": "" }, { "name": "prostaglandin-E synthase activity", "id": "GO:0050220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050220", "evidence": [ { "database": "UniProtKB", "id": "Q5IHX7", "url": "https://www.uniprot.org/uniprotkb/Q5IHX7" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5IHX7", "url": "https://www.uniprot.org/uniprotkb/Q5IHX7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q5IHX7", "url": "https://www.uniprot.org/uniprotkb/Q5IHX7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration involved in gastrulation", "id": "GO:0042074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042074", "evidence": [ { "database": "UniProtKB", "id": "Q5IHX7", "url": "https://www.uniprot.org/uniprotkb/Q5IHX7" } ], "pmid": "" }, { "name": "prostaglandin biosynthetic process", "id": "GO:0001516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001516", "evidence": [ { "database": "UniProtKB", "id": "Q5IHX7", "url": "https://www.uniprot.org/uniprotkb/Q5IHX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5M7X9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 341, "chemical_mass": 38585.0, "gene_names": "mul1a;mul1;zgc:92166", "protein_name": "Mitochondrial ubiquitin ligase activator of nfkb 1-A", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of metabolic process", "id": "GO:0009893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009893", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "mitochondrion localization", "id": "GO:0051646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051646", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q5M7X9", "url": "https://www.uniprot.org/uniprotkb/Q5M7X9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5PR67-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 333, "chemical_mass": 38226.0, "gene_names": "eif3hb;eif3hb;eif3s3b;zgc:123049", "protein_name": "Eukaryotic translation initiation factor 3 subunit H-B", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10286", "name": "prostate carcinoma", "description": "A prostate cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:10286", "evidence": [ { "id": "10286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10286" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" } ], "molecular_function": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q5PR67", "url": "https://www.uniprot.org/uniprotkb/Q5PR67" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5PRA2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5PRA2", "url": "https://www.uniprot.org/uniprotkb/Q5PRA2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 920, "chemical_mass": 102964.0, "gene_names": "dhtkd1;E1a;OADC-E1;OADH-E1;dhtkd1;zgc:101818", "protein_name": "2-oxoadipate dehydrogenase complex component E1", "disease": [ { "disease_id": "DOID:0110170", "name": "Charcot-Marie-Tooth disease axonal type 2Q", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in a heterozygous loss-of-function mutation in the DHTKD1 gene on chromosome 10p14.", "url": "https://disease-ontology.org/term/DOID:0110170", "evidence": [ { "id": "0110170", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110170" } ], "weight": 0.0 }, { "disease_id": "DOID:0111453", "name": "2-aminoadipic 2-oxoadipic aciduria", "description": "An amino acid metabolic disorder characterized by defects in L-lysine degradation resulting in variable neurological symptoms but in many cases patients are asymptomatic that has_material_basis_in homozygous or compound heterozygous mutation in the DHTKD1 gene on chromosome 10p14.", "url": "https://disease-ontology.org/term/DOID:0111453", "evidence": [ { "id": "0111453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111453" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5PRA2", "url": "https://www.uniprot.org/uniprotkb/Q5PRA2" } ], "pmid": "" } ], "biological_process": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "Q5PRA2", "url": "https://www.uniprot.org/uniprotkb/Q5PRA2" } ], "pmid": "" } ], "molecular_function": [ { "name": "thiamine pyrophosphate binding", "id": "GO:0030976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030976", "evidence": [ { "database": "UniProtKB", "id": "Q5PRA2", "url": "https://www.uniprot.org/uniprotkb/Q5PRA2" } ], "pmid": "" }, { "name": "2-oxoadipate dehydrogenase activity", "id": "GO:0160166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160166", "evidence": [ { "database": "UniProtKB", "id": "Q5PRA2", "url": "https://www.uniprot.org/uniprotkb/Q5PRA2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5PRC7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 211, "chemical_mass": 22438.0, "gene_names": "nabp1a;nabp1;fc60e10;fi33c08;nabp1a;nabp1;obfc2aa;obfc2a;ssb2;wu:fc60e10;wu:fi33c08;zgc:101644", "protein_name": "SOSS complex subunit B2", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" }, { "name": "SOSS complex", "id": "GO:0070876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070876", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" }, { "name": "mitotic G2/M transition checkpoint", "id": "GO:0044818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044818", "evidence": [ { "database": "UniProtKB", "id": "Q5PRC7", "url": "https://www.uniprot.org/uniprotkb/Q5PRC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5PRC7-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Thr189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q5PRC7-1", "start_pos": "196", "end_pos": "196", "site_lbl": "Thr196", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 196, "start_aa": "Thr", "end_pos": 196, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr196", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RFV4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 293, "chemical_mass": 33130.0, "gene_names": "rnf144aa;rnf144aa;si:ch211-276e8.1", "protein_name": "Probable E3 ubiquitin-protein ligase RNF144A-A", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q5RFV4", "url": "https://www.uniprot.org/uniprotkb/Q5RFV4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RGA4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 822, "chemical_mass": 92803.0, "gene_names": "mysm1;im:7153144;si:ch211-59d15.8", "protein_name": "Histone H2A deubiquitinase MYSM1", "disease": [ { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "metal-dependent deubiquitinase activity", "id": "GO:0140492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140492", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" }, { "name": "histone H2A deubiquitinase activity", "id": "GO:0140950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140950", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5RGA4", "url": "https://www.uniprot.org/uniprotkb/Q5RGA4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RH51-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 409, "chemical_mass": 45869.0, "gene_names": "fam20b;fam20b;si:ch211-195o19.3;zgc:136944", "protein_name": "Glycosaminoglycan xylosylkinase", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "pmid": "" }, { "name": "phosphotransferase activity, alcohol group as acceptor", "id": "GO:0016773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016773", "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "pmid": "" } ], "biological_process": [ { "name": "embryonic cranial skeleton morphogenesis", "id": "GO:0048701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048701", "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "pmid": "" }, { "name": "proteoglycan biosynthetic process", "id": "GO:0030166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030166", "evidence": [ { "database": "UniProtKB", "id": "Q5RH51", "url": "https://www.uniprot.org/uniprotkb/Q5RH51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5RH51-1", "start_pos": "193", "end_pos": "193", "site_lbl": "Asn193", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 193, "start_aa": "Asn", "end_pos": 193, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn193", "evidence": [ { "id": "Q5RH51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RH51#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RH95-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 359, "chemical_mass": 41475.0, "gene_names": "rsad2;SAND;rsad2;si:ch211-276e8.2;vig1;zgc:112342", "protein_name": "S-adenosylmethionine-dependent nucleotide dehydratase RSAD2", "disease": [ { "disease_id": "DOID:1273", "name": "respiratory syncytial virus infectious disease", "description": "A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus (Orthopneumovirus hominis), which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress.", "url": "https://disease-ontology.org/term/DOID:1273", "evidence": [ { "id": "1273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1273" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "positive regulation of immune response", "id": "GO:0050778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050778", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "inflammatory response to wounding", "id": "GO:0090594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090594", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "Q5RH95", "url": "https://www.uniprot.org/uniprotkb/Q5RH95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RHH4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1745, "chemical_mass": 197780.0, "gene_names": "ift172;ift172;si:dkey-221h15.5", "protein_name": "Intraflagellar transport protein 172 homolog", "disease": [ { "disease_id": "DOID:0050651", "name": "atrioventricular septal defect", "description": "A congenital heart septal defect characterized by an abnormal or inadequate fusion of the superior and inferior endocardial cushions with the mid portion of the atrial septum and the muscular portion of the ventricular septum, thus allowing extra blood to circulate the lungs.", "url": "https://disease-ontology.org/term/DOID:0050651", "evidence": [ { "id": "0050651", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050651" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0081009", "name": "Bardet-Biedl syndrome 20", "description": "A Bardet-Biedl syndrome that is characterized by rod-cone dystrophy, postaxial polydactyly, truncal obesity, renal anomalies, and learning disability, as well as hypogonadism in males and genital abnormalities in females and that has_material_basis_in homozygous mutation in the IFT172 gene on chromosome 2p23.", "url": "https://disease-ontology.org/term/DOID:0081009", "evidence": [ { "id": "0081009", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081009" } ], "weight": 0.0 }, { "disease_id": "DOID:0110091", "name": "short-rib thoracic dysplasia 10 with or without polydactyly", "description": "An asphyxiating thoracic dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the IFT172 gene on chromosome 2p23.", "url": "https://disease-ontology.org/term/DOID:0110091", "evidence": [ { "id": "0110091", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110091" } ], "weight": 0.0 }, { "disease_id": "DOID:0110363", "name": "retinitis pigmentosa 71", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the IFT172 gene on chromosome 2p23.", "url": "https://disease-ontology.org/term/DOID:0110363", "evidence": [ { "id": "0110363", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110363" } ], "weight": 0.0 }, { "disease_id": "DOID:14679", "name": "VACTERL association", "description": "A syndrome that is characterized by the presence of at least three of the following: vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities.", "url": "https://disease-ontology.org/term/DOID:14679", "evidence": [ { "id": "14679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14679" } ], "weight": 0.0 }, { "disease_id": "DOID:2975", "name": "cystic kidney disease", "description": "A kidney disease that is characterized by the formation of cysts (fluid-filled sacs) in and around the kidney.", "url": "https://disease-ontology.org/term/DOID:2975", "evidence": [ { "id": "2975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2975" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" } ], "biological_process": [ { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" }, { "name": "regulation of TOR signaling", "id": "GO:0032006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032006", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" }, { "name": "pronephros development", "id": "GO:0048793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048793", "evidence": [ { "database": "UniProtKB", "id": "Q5RHH4", "url": "https://www.uniprot.org/uniprotkb/Q5RHH4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RIC5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 807, "chemical_mass": 90490.0, "gene_names": "mcm3;MCM3z;cb32;chunp6867;mcm3;wu:fa26g03", "protein_name": "DNA replication licensing factor MCM3", "disease": [], "biological_process": [ { "name": "DNA strand elongation involved in DNA replication", "id": "GO:0006271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006271", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "mitotic DNA replication initiation", "id": "GO:1902975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902975", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" }, { "name": "MCM complex", "id": "GO:0042555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042555", "evidence": [ { "database": "UniProtKB", "id": "Q5RIC5", "url": "https://www.uniprot.org/uniprotkb/Q5RIC5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RIU9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 309, "chemical_mass": 35708.0, "gene_names": "srd5a3;S5AR 3;fj40g12;si:ch211-278f21.3;srd5a2l;srd5a3;wu:fj40g12", "protein_name": "Polyprenal reductase", "disease": [ { "disease_id": "DOID:0050570", "name": "congenital disorder of glycosylation type I", "description": "A congenital disorder of glycosylation characterized by under-glycosylated serum glycoproteins.", "url": "https://disease-ontology.org/term/DOID:0050570", "evidence": [ { "id": "0050570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050570" } ], "weight": 0.0 }, { "disease_id": "DOID:0050807", "name": "Kahrizi syndrome", "description": "A syndrome that is characterized by mental retardation, cataracts, coloboma, kyphosis, and coarse facial features and has_material_basis_in mutation in the SRD5A3 gene.", "url": "https://disease-ontology.org/term/DOID:0050807", "evidence": [ { "id": "0050807", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050807" } ], "weight": 0.0 }, { "disease_id": "DOID:0080568", "name": "congenital disorder of glycosylation Iq", "description": "A congenital disorder of glycosylation I that is characterized by a highly variable phenotype typically presenting with severe visual impairment, variable ocular anomalies (such as optic nerve hypoplasia/atrophy, iris and optic nerve coloboma, congenital cataract, glaucoma), intellectual disability, cerebellar abnormalities, nystagmus, hypotonia, ataxia, and/or ichthyosiform skin lesions and has_material_basis_in homozygous or compound heterozygous mutation in the SRD5A3 gene on chromosome 4q12.", "url": "https://disease-ontology.org/term/DOID:0080568", "evidence": [ { "id": "0080568", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080568" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "pmid": "" } ], "biological_process": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "pmid": "" }, { "name": "polyprenol catabolic process", "id": "GO:0016095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016095", "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "pmid": "" }, { "name": "dolichyl monophosphate biosynthetic process", "id": "GO:0043048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043048", "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor", "id": "GO:0016628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016628", "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "pmid": "" }, { "name": "3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity", "id": "GO:0047751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047751", "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "pmid": "" }, { "name": "polyprenal reductase activity", "id": "GO:0160198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160198", "evidence": [ { "database": "UniProtKB", "id": "Q5RIU9", "url": "https://www.uniprot.org/uniprotkb/Q5RIU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5RJA1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 848, "chemical_mass": 93762.0, "gene_names": "rfx6;si:dkeyp-93d12.2", "protein_name": "DNA-binding protein RFX6", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "positive regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0035774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035774", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "pancreatic D cell differentiation", "id": "GO:0003311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003311", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "pancreatic epsilon cell differentiation", "id": "GO:0090104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090104", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "type B pancreatic cell differentiation", "id": "GO:0003309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003309", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "pancreatic A cell differentiation", "id": "GO:0003310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003310", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q5RJA1", "url": "https://www.uniprot.org/uniprotkb/Q5RJA1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5SNX7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5SNX7", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 660, "chemical_mass": 73820.0, "gene_names": "galc;galca;galcl;galc;si:ch211-199l3.4;zgc:92561", "protein_name": "Galactocerebrosidase", "disease": [ { "disease_id": "DOID:10587", "name": "Krabbe disease", "description": "", "url": "https://disease-ontology.org/term/DOID:10587", "evidence": [ { "id": "10587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10587" } ], "weight": 0.0 }, { "disease_id": "DOID:11949", "name": "Creutzfeldt-Jakob disease", "description": "", "url": "https://disease-ontology.org/term/DOID:11949", "evidence": [ { "id": "11949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11949" } ], "weight": 0.0 }, { "disease_id": "DOID:13276", "name": "Mycoplasma pneumoniae pneumonia", "description": "A bacterial pneumonia that is caused by the bacterial species Mycoplasma pneumoniae. The symptoms include chest pain, chills, dry cough which is not bloody, excessive sweating, fever, headache and sore throat.", "url": "https://disease-ontology.org/term/DOID:13276", "evidence": [ { "id": "13276", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13276" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5SNX7", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q5SNX7", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7" } ], "pmid": "" } ], "molecular_function": [ { "name": "galactosylceramidase activity", "id": "GO:0004336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004336", "evidence": [ { "database": "UniProtKB", "id": "Q5SNX7", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7" } ], "pmid": "" } ], "biological_process": [ { "name": "galactosylceramide catabolic process", "id": "GO:0006683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006683", "evidence": [ { "database": "UniProtKB", "id": "Q5SNX7", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Asn147", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 147, "start_aa": "Asn", "end_pos": 147, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn147", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Asn293", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 293, "start_aa": "Asn", "end_pos": 293, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn293", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Asn356", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 356, "start_aa": "Asn", "end_pos": 356, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn356", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "413", "end_pos": "413", "site_lbl": "Asn413", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 413, "start_aa": "Asn", "end_pos": 413, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn413", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "465", "end_pos": "465", "site_lbl": "Asn465", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 465, "start_aa": "Asn", "end_pos": 465, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn465", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Asn495", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 495, "start_aa": "Asn", "end_pos": 495, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn495", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Asn499", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 499, "start_aa": "Asn", "end_pos": 499, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn499", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Asn537", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 537, "start_aa": "Asn", "end_pos": 537, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn537", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5SNX7-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Asn578", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 578, "start_aa": "Asn", "end_pos": 578, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn578", "evidence": [ { "id": "Q5SNX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNX7#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5SPB6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 196, "chemical_mass": 22016.0, "gene_names": "chac1;cb1014;chac1;wu:fb93a10;wu:fp64e03", "protein_name": "Glutathione-specific gamma-glutamylcyclotransferase 1", "disease": [], "biological_process": [ { "name": "glutathione catabolic process", "id": "GO:0006751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006751", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "negative regulation of protein processing", "id": "GO:0010955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010955", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" } ], "molecular_function": [ { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" }, { "name": "glutathione specific gamma-glutamylcyclotransferase activity", "id": "GO:0061928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061928", "evidence": [ { "database": "UniProtKB", "id": "Q5SPB6", "url": "https://www.uniprot.org/uniprotkb/Q5SPB6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5TYM7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TYM7", "url": "https://www.uniprot.org/uniprotkb/Q5TYM7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 744, "chemical_mass": 80833.0, "gene_names": "caiap;caiap;si:dkey-86e18.2", "protein_name": "CARD- and ANK-domain containing inflammasome adapter protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5TYM7", "url": "https://www.uniprot.org/uniprotkb/Q5TYM7" } ], "pmid": "" } ], "biological_process": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "Q5TYM7", "url": "https://www.uniprot.org/uniprotkb/Q5TYM7" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q5TYM7", "url": "https://www.uniprot.org/uniprotkb/Q5TYM7" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "Q5TYM7", "url": "https://www.uniprot.org/uniprotkb/Q5TYM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5TYV4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 483, "chemical_mass": 56073.0, "gene_names": "vipas39;hSPE-39;si:ch211-20b12.1;spe39;vipar;vipas39;wu:fb63f10", "protein_name": "Spermatogenesis-defective protein 39 homolog", "disease": [ { "disease_id": "DOID:0050763", "name": "ARC syndrome", "description": "A syndrome that is characterized by congenital joint contractures, renal tubular dysfunction, cholestasis, severe failure to thrive, ichthyosis and a defect in platelet alpha-granule biogenesis and that has_material_basis_in homozygous or compound heterozygous mutation in the VPS33B gene or homozygous or compound heterozygous mutation in the VIPAR gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0050763", "evidence": [ { "id": "0050763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050763" } ], "weight": 0.0 }, { "disease_id": "DOID:0111354", "name": "arthrogryposis, renal dysfunction, and cholestasis 2", "description": "An arthrogryposis, renal dysfunction, and cholestasis that has_material_basis_in homozygous or compound heterozygous mutation in VIPAS39 on 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0111354", "evidence": [ { "id": "0111354", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111354" } ], "weight": 0.0 } ], "biological_process": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" }, { "name": "hepaticobiliary system development", "id": "GO:0061008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061008", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q5TYV4", "url": "https://www.uniprot.org/uniprotkb/Q5TYV4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5TYX1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 327, "chemical_mass": 37421.0, "gene_names": "mixl1;bon/mixer;bon;mix-like;mixer;mixl1;mix", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "endoderm development", "id": "GO:0007492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007492", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "embryonic heart tube development", "id": "GO:0035050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035050", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "endoderm formation", "id": "GO:0001706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001706", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "midbrain development", "id": "GO:0030901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030901", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5TZ24-3", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 614, "chemical_mass": 69345.0, "gene_names": "moxd1;fj65c11;moxd1;si:ch211-193l17.1;si:dkey-266k12.5;si:dkeyp-119b4.5;wu:fj65c11", "protein_name": "DBH-like monooxygenase protein 1 homolog", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "pmid": "" }, { "name": "secretory granule membrane", "id": "GO:0030667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030667", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "pmid": "" } ], "molecular_function": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "pmid": "" }, { "name": "dopamine beta-monooxygenase activity", "id": "GO:0004500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004500", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "pmid": "" } ], "biological_process": [ { "name": "dopamine catabolic process", "id": "GO:0042420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042420", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "pmid": "" }, { "name": "octopamine biosynthetic process", "id": "GO:0006589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006589", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "pmid": "" }, { "name": "norepinephrine biosynthetic process", "id": "GO:0042421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042421", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ24", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5TZ24-3", "start_pos": "116", "end_pos": "116", "site_lbl": "Asn116", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 116, "start_aa": "Asn", "end_pos": 116, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn116", "evidence": [ { "id": "Q5TZ24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5TZ24-3", "start_pos": "249", "end_pos": "249", "site_lbl": "Asn249", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 249, "start_aa": "Asn", "end_pos": 249, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn249", "evidence": [ { "id": "Q5TZ24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5TZ24-3", "start_pos": "454", "end_pos": "454", "site_lbl": "Asn454", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 454, "start_aa": "Asn", "end_pos": 454, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn454", "evidence": [ { "id": "Q5TZ24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5TZ24-3", "start_pos": "519", "end_pos": "519", "site_lbl": "Asn519", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 519, "start_aa": "Asn", "end_pos": 519, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn519", "evidence": [ { "id": "Q5TZ24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ24#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5TZ66-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 204, "chemical_mass": 22857.0, "gene_names": "snap25a;Snap;fj42b02;fj45g04;fj48c02;si:dkeyp-8f4.6;snap25.1;snap25a;snap25;wu:fj42b02;wu:fj45g04;wu:fj48c02", "protein_name": "Synaptosomal-associated protein 25-A", "disease": [ { "disease_id": "DOID:0110683", "name": "developmental and epileptic encephalopathy 117", "description": "A developmental and epileptic encephalopathy that is characterized by global developmental delay, hypotonia, delayed walking or inability to walk, and variably impaired intellectual development with poor or absent speech and that has_material_basis_in heterozygous mutation in the SNAP25 gene on chromosome 20p11.", "url": "https://disease-ontology.org/term/DOID:0110683", "evidence": [ { "id": "0110683", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110683" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex", "id": "GO:0070032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070032", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" } ], "biological_process": [ { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031629", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "syntaxin-1 binding", "id": "GO:0017075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017075", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ66", "url": "https://www.uniprot.org/uniprotkb/Q5TZ66" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5TZD3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TZD3", "url": "https://www.uniprot.org/uniprotkb/Q5TZD3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 562, "chemical_mass": 63863.0, "gene_names": "si:dkey-239i20.2;si:ch211-191d7.2;si:dkey-239i20.2;zgc:171329", "protein_name": "Flavin-containing monooxygenase", "disease": [ { "disease_id": "DOID:0080361", "name": "trimethylaminuria", "description": "An inherited metabolic disorder characterized by the inability to break down trimethylamine and has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding flavin-containing monooxygenase-3 on chromosome 1q24.", "url": "https://disease-ontology.org/term/DOID:0080361", "evidence": [ { "id": "0080361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080361" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:655", "name": "inherited metabolic disorder", "description": "A disease of metabolism that is characterized by enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to inherited enzyme abnormality.", "url": "https://disease-ontology.org/term/DOID:655", "evidence": [ { "id": "655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:655" } ], "weight": 0.0 } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD3", "url": "https://www.uniprot.org/uniprotkb/Q5TZD3" } ], "pmid": "" } ], "molecular_function": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD3", "url": "https://www.uniprot.org/uniprotkb/Q5TZD3" } ], "pmid": "" }, { "name": "NAD(P)H oxidase H2O2-forming activity", "id": "GO:0016174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016174", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD3", "url": "https://www.uniprot.org/uniprotkb/Q5TZD3" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD3", "url": "https://www.uniprot.org/uniprotkb/Q5TZD3" } ], "pmid": "" }, { "name": "N,N-dimethylaniline monooxygenase activity", "id": "GO:0004499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004499", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD3", "url": "https://www.uniprot.org/uniprotkb/Q5TZD3" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD3", "url": "https://www.uniprot.org/uniprotkb/Q5TZD3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5U374-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 564, "chemical_mass": 62963.0, "gene_names": "klhl12;klhl12;si:dkeyp-53e12.5;wu:fi60g03;zgc:92570", "protein_name": "Kelch-like protein 12", "disease": [], "biological_process": [ { "name": "neural crest formation", "id": "GO:0014029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014029", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "neural crest cell development", "id": "GO:0014032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014032", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "COPII vesicle coating", "id": "GO:0048208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048208", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "convergent extension involved in axis elongation", "id": "GO:0060028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060028", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "Q5U374", "url": "https://www.uniprot.org/uniprotkb/Q5U374" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5U3E1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 215, "chemical_mass": 24311.0, "gene_names": "rab11a;rab11a;wu:fi15h09;zgc:103679", "protein_name": "small monomeric GTPase", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:10155", "name": "intestinal cancer", "description": "A gastrointestinal system cancer that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:10155", "evidence": [ { "id": "10155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10155" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "postsynaptic recycling endosome", "id": "GO:0098837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098837", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" } ], "biological_process": [ { "name": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "id": "GO:0098887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098887", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "Kupffer's vesicle development", "id": "GO:0070121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070121", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "melanosome transport", "id": "GO:0032402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032402", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "regulation of neuronal action potential", "id": "GO:0098908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098908", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "Q5U3E1", "url": "https://www.uniprot.org/uniprotkb/Q5U3E1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5U3G1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 271, "chemical_mass": 29284.0, "gene_names": "colec11;colec11;wu:fb82e09;zgc:103572", "protein_name": "Collectin-11", "disease": [ { "disease_id": "DOID:0060576", "name": "3MC syndrome 2", "description": "A 3MC syndrome that has_material_basis_in autosomal recessive inheritance of homozygous mutation in the collectin subfamily member 11 gene (COLEC11) on chromosome 2p25.", "url": "https://disease-ontology.org/term/DOID:0060576", "evidence": [ { "id": "0060576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060576" } ], "weight": 0.0 }, { "disease_id": "DOID:674", "name": "cleft palate", "description": "An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.", "url": "https://disease-ontology.org/term/DOID:674", "evidence": [ { "id": "674", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:674" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "oligosaccharide binding", "id": "GO:0070492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070492", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" }, { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" }, { "name": "fucose binding", "id": "GO:0042806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042806", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" }, { "name": "calcium-dependent carbohydrate binding", "id": "GO:0120153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120153", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" } ], "biological_process": [ { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" }, { "name": "antimicrobial humoral response", "id": "GO:0019730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019730", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" }, { "name": "complement activation, lectin pathway", "id": "GO:0001867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001867", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5U3G1-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5U3S1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 488, "chemical_mass": 54891.0, "gene_names": "katnal1;katnal1;zgc:101696", "protein_name": "Katanin p60 ATPase-containing subunit A-like 1", "disease": [], "molecular_function": [ { "name": "microtubule severing ATPase activity", "id": "GO:0008568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008568", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule severing", "id": "GO:0051013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051013", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q5U3S1", "url": "https://www.uniprot.org/uniprotkb/Q5U3S1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5U3S1-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5U403-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U403", "url": "https://www.uniprot.org/uniprotkb/Q5U403" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 400, "chemical_mass": 44599.0, "gene_names": "mvd;mvda;mvd;zgc:100824", "protein_name": "Diphosphomevalonate decarboxylase", "disease": [ { "disease_id": "DOID:3805", "name": "porokeratosis", "description": "", "url": "https://disease-ontology.org/term/DOID:3805", "evidence": [ { "id": "3805", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3805" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5U403", "url": "https://www.uniprot.org/uniprotkb/Q5U403" } ], "pmid": "" }, { "name": "diphosphomevalonate decarboxylase activity", "id": "GO:0004163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004163", "evidence": [ { "database": "UniProtKB", "id": "Q5U403", "url": "https://www.uniprot.org/uniprotkb/Q5U403" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5U403", "url": "https://www.uniprot.org/uniprotkb/Q5U403" } ], "pmid": "" } ], "biological_process": [ { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "Q5U403", "url": "https://www.uniprot.org/uniprotkb/Q5U403" } ], "pmid": "" }, { "name": "keratinocyte development", "id": "GO:0003334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003334", "evidence": [ { "database": "UniProtKB", "id": "Q5U403", "url": "https://www.uniprot.org/uniprotkb/Q5U403" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "Q5U403", "url": "https://www.uniprot.org/uniprotkb/Q5U403" } ], "pmid": "" }, { "name": "isopentenyl diphosphate biosynthetic process, mevalonate pathway", "id": "GO:0019287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019287", "evidence": [ { "database": "UniProtKB", "id": "Q5U403", "url": "https://www.uniprot.org/uniprotkb/Q5U403" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5U9X3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U9X3", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 867, "chemical_mass": 97136.0, "gene_names": "gprc6a;ZO6;gprc6a", "protein_name": "G protein-coupled receptor family C group 6 member A", "disease": [], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q5U9X3", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3" } ], "pmid": "" }, { "name": "amino acid binding", "id": "GO:0016597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016597", "evidence": [ { "database": "UniProtKB", "id": "Q5U9X3", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3" } ], "pmid": "" }, { "name": "glutamate binding", "id": "GO:0016595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016595", "evidence": [ { "database": "UniProtKB", "id": "Q5U9X3", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5U9X3", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "Q5U9X3", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "Q5U9X3", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Asn296", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 296, "start_aa": "Asn", "end_pos": 296, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn296", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "308", "end_pos": "308", "site_lbl": "Asn308", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 308, "start_aa": "Asn", "end_pos": 308, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn308", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "336", "end_pos": "336", "site_lbl": "Asn336", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 336, "start_aa": "Asn", "end_pos": 336, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn336", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Asn356", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 356, "start_aa": "Asn", "end_pos": 356, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn356", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Asn370", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 370, "start_aa": "Asn", "end_pos": 370, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn370", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Asn51", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 51, "start_aa": "Asn", "end_pos": 51, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn51", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "527", "end_pos": "527", "site_lbl": "Asn527", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 527, "start_aa": "Asn", "end_pos": 527, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn527", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Asn547", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 547, "start_aa": "Asn", "end_pos": 547, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn547", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Asn55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 55, "start_aa": "Asn", "end_pos": 55, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn55", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Asn97", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 97, "start_aa": "Asn", "end_pos": 97, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn97", "evidence": [ { "id": "Q5U9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q5U9X3-1", "start_pos": "386", "end_pos": "386", "site_lbl": "Lys386", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "M", "comment": "Induces nonselectivity for Arg and Glu.", "evidence": [ { "database": "UniProtKB", "id": "Q5U9X3", "url": "https://www.uniprot.org/uniprotkb/Q5U9X3" }, { "database": "PubMed", "id": "15537883", "url": "https://glygen.org/publication/PubMed/15537883" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5VSE6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 412, "chemical_mass": 46047.0, "gene_names": "kcnk13b;kcnk13", "protein_name": "Potassium channel, subfamily K, member 13", "disease": [], "biological_process": [ { "name": "regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900225", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" }, { "name": "regulation of resting membrane potential", "id": "GO:0060075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060075", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" }, { "name": "regulation of excitatory synapse pruning", "id": "GO:1905810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905810", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" } ], "molecular_function": [ { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "Q5VSE6", "url": "https://www.uniprot.org/uniprotkb/Q5VSE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5XJ54-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJ54", "url": "https://www.uniprot.org/uniprotkb/Q5XJ54" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 326, "chemical_mass": 36335.0, "gene_names": "glrx3;glrx3;txnl2;wu:fb38e09;zgc:103648", "protein_name": "Glutaredoxin 3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ54", "url": "https://www.uniprot.org/uniprotkb/Q5XJ54" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ54", "url": "https://www.uniprot.org/uniprotkb/Q5XJ54" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ54", "url": "https://www.uniprot.org/uniprotkb/Q5XJ54" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ54", "url": "https://www.uniprot.org/uniprotkb/Q5XJ54" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ54", "url": "https://www.uniprot.org/uniprotkb/Q5XJ54" } ], "pmid": "" }, { "name": "hemoglobin metabolic process", "id": "GO:0020027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020027", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ54", "url": "https://www.uniprot.org/uniprotkb/Q5XJ54" } ], "pmid": "" }, { "name": "multicellular organismal-level iron ion homeostasis", "id": "GO:0060586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060586", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ54", "url": "https://www.uniprot.org/uniprotkb/Q5XJ54" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5XJ57-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 241, "chemical_mass": 27966.0, "gene_names": "mettl1;METTL1;mettl1;zgc:103636", "protein_name": "tRNA (guanine-N(7)-)-methyltransferase", "disease": [], "biological_process": [ { "name": "RNA (guanine-N7)-methylation", "id": "GO:0036265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036265", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" }, { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" }, { "name": "tRNA (guanine-N7)-methylation", "id": "GO:0106004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106004", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" }, { "name": "tRNA methyltransferase complex", "id": "GO:0043527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043527", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" }, { "name": "tRNA (m7G46) methyltransferase complex", "id": "GO:0106143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106143", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" }, { "name": "tRNA (guanine(46)-N7)-methyltransferase activity", "id": "GO:0008176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008176", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" }, { "name": "internal mRNA (guanine-N7-)-methyltransferase activity", "id": "GO:0160090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160090", "evidence": [ { "database": "UniProtKB", "id": "Q5XJ57", "url": "https://www.uniprot.org/uniprotkb/Q5XJ57" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5XJQ5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 393, "chemical_mass": 44135.0, "gene_names": "exosc9;exosc9;im:6909054;zgc:101680", "protein_name": "Exosome complex component RRP45", "disease": [ { "disease_id": "DOID:0112323", "name": "pontocerebellar hypoplasia type 1D", "description": "A pontocerebellar hypoplasia type 1 characterized by severe hypotonia and motor neuronopathy detectable at birth or in infancy that has_material_basis_in homozygous or compound heterozygous mutation in the EXOSC9 gene on chromosome 4q27.", "url": "https://disease-ontology.org/term/DOID:0112323", "evidence": [ { "id": "0112323", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112323" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "U1 snRNA 3'-end processing", "id": "GO:0034473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034473", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "U5 snRNA 3'-end processing", "id": "GO:0034476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034476", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA 3'-UTR AU-rich region binding", "id": "GO:0035925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035925", "evidence": [ { "database": "UniProtKB", "id": "Q5XJQ5", "url": "https://www.uniprot.org/uniprotkb/Q5XJQ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q5YB40-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5YB40", "url": "https://www.uniprot.org/uniprotkb/Q5YB40" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 360, "chemical_mass": 40964.0, "gene_names": "mfng;mfng;zgc:136666", "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase manic fringe", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q5YB40", "url": "https://www.uniprot.org/uniprotkb/Q5YB40" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5YB40", "url": "https://www.uniprot.org/uniprotkb/Q5YB40" } ], "pmid": "" }, { "name": "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity", "id": "GO:0033829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033829", "evidence": [ { "database": "UniProtKB", "id": "Q5YB40", "url": "https://www.uniprot.org/uniprotkb/Q5YB40" } ], "pmid": "" } ], "biological_process": [ { "name": "pattern specification process", "id": "GO:0007389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007389", "evidence": [ { "database": "UniProtKB", "id": "Q5YB40", "url": "https://www.uniprot.org/uniprotkb/Q5YB40" } ], "pmid": "" }, { "name": "regulation of Notch signaling pathway", "id": "GO:0008593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008593", "evidence": [ { "database": "UniProtKB", "id": "Q5YB40", "url": "https://www.uniprot.org/uniprotkb/Q5YB40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q5YB40-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Asn214", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 214, "start_aa": "Asn", "end_pos": 214, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn214", "evidence": [ { "id": "Q5YB40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5YB40#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q66HZ2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66HZ2", "url": "https://www.uniprot.org/uniprotkb/Q66HZ2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 405, "chemical_mass": 44500.0, "gene_names": "rimklb;fam80b;naags;rimkla;rimklb;wu:fc60e09;zgc:92164", "protein_name": "Beta-citrylglutamate synthase B", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q66HZ2", "url": "https://www.uniprot.org/uniprotkb/Q66HZ2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q66HZ2", "url": "https://www.uniprot.org/uniprotkb/Q66HZ2" } ], "pmid": "" }, { "name": "N-acetyl-L-aspartate-L-glutamate ligase activity", "id": "GO:0072590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072590", "evidence": [ { "database": "UniProtKB", "id": "Q66HZ2", "url": "https://www.uniprot.org/uniprotkb/Q66HZ2" } ], "pmid": "" }, { "name": "citrate-L-glutamate ligase activity", "id": "GO:0072591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072591", "evidence": [ { "database": "UniProtKB", "id": "Q66HZ2", "url": "https://www.uniprot.org/uniprotkb/Q66HZ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66HZ2", "url": "https://www.uniprot.org/uniprotkb/Q66HZ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q66HZ2-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Thr382", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q66I14-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I14", "url": "https://www.uniprot.org/uniprotkb/Q66I14" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 447, "chemical_mass": 47456.0, "gene_names": "sephs3;cb701;sephs2;sephs3;sps2;zgc:92096", "protein_name": "Selenide, water dikinase 3", "disease": [ { "disease_id": "DOID:0050860", "name": "colorectal adenoma", "description": "An intestinal benign neoplasm that has_material_basis_in epithelial tissue of glandular origin and is located_in colon and located_in rectum.", "url": "https://disease-ontology.org/term/DOID:0050860", "evidence": [ { "id": "0050860", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050860" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "selenide, water dikinase activity", "id": "GO:0004756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004756", "evidence": [ { "database": "UniProtKB", "id": "Q66I14", "url": "https://www.uniprot.org/uniprotkb/Q66I14" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q66I14", "url": "https://www.uniprot.org/uniprotkb/Q66I14" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q66I14", "url": "https://www.uniprot.org/uniprotkb/Q66I14" } ], "pmid": "" } ], "biological_process": [ { "name": "selenocysteine biosynthetic process", "id": "GO:0016260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016260", "evidence": [ { "database": "UniProtKB", "id": "Q66I14", "url": "https://www.uniprot.org/uniprotkb/Q66I14" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q66I14", "url": "https://www.uniprot.org/uniprotkb/Q66I14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q66I23-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 410, "chemical_mass": 46983.0, "gene_names": "tgfb3;tgfb3;wu:fc78g09;zgc:92058", "protein_name": "Transforming growth factor beta", "disease": [ { "disease_id": "DOID:0050431", "name": "arrhythmogenic right ventricular cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle and limited or no involvement of the left ventricle.", "url": "https://disease-ontology.org/term/DOID:0050431", "evidence": [ { "id": "0050431", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050431" } ], "weight": 0.0 }, { "disease_id": "DOID:0070236", "name": "Loeys-Dietz syndrome 5", "description": "A Loeys-Dietz syndrome that has_material_basis_in heterozygous mutation in the TGFB3 gene on chromosome 14q24.", "url": "https://disease-ontology.org/term/DOID:0070236", "evidence": [ { "id": "0070236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070236" } ], "weight": 0.0 }, { "disease_id": "DOID:0110070", "name": "arrhythmogenic right ventricular dysplasia 1", "description": "An arrhythmogenic right ventricular dysplasia that has_material_basis_in heterozygous mutation in the TGFB3 gene on chromosome 14q24.", "url": "https://disease-ontology.org/term/DOID:0110070", "evidence": [ { "id": "0110070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110070" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "hematopoietic stem cell differentiation", "id": "GO:0060218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "positive regulation of cell division", "id": "GO:0051781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051781", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "regulation of ossification", "id": "GO:0030278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030278", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "regulation of cartilage development", "id": "GO:0061035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061035", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor binding", "id": "GO:0005160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005160", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "Q66I23", "url": "https://www.uniprot.org/uniprotkb/Q66I23" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q66PG1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 750, "chemical_mass": 86987.0, "gene_names": "large2;gyltl1b;large2;si:ch211-206g24.1;si:ch211-282n12.1", "protein_name": "Xylosyl- and glucuronyltransferase LARGE2s", "disease": [], "molecular_function": [ { "name": "xylosyltransferase activity", "id": "GO:0042285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042285", "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "pmid": "" }, { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "pmid": "" } ], "biological_process": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via mannose", "id": "GO:0035269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035269", "evidence": [ { "database": "UniProtKB", "id": "Q66PG1", "url": "https://www.uniprot.org/uniprotkb/Q66PG1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q66PG1-1", "start_pos": "116", "end_pos": "116", "site_lbl": "Asn116", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 116, "start_aa": "Asn", "end_pos": 116, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn116", "evidence": [ { "id": "Q66PG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66PG1-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Asn142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 142, "start_aa": "Asn", "end_pos": 142, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn142", "evidence": [ { "id": "Q66PG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66PG1-1", "start_pos": "228", "end_pos": "228", "site_lbl": "Asn228", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 228, "start_aa": "Asn", "end_pos": 228, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn228", "evidence": [ { "id": "Q66PG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q66PG1-1", "start_pos": "266", "end_pos": "266", "site_lbl": "Asn266", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 266, "start_aa": "Asn", "end_pos": 266, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn266", "evidence": [ { "id": "Q66PG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66PG1#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q68EK2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 470, "chemical_mass": 54102.0, "gene_names": "calcrla;calcrl;si:dkey-249o24.2;zgc:100872", "protein_name": "Calcitonin gene-related peptide type 1 receptor", "disease": [ { "disease_id": "DOID:0050580", "name": "hereditary lymphedema", "description": "A lymphedema commonly located_in legs, caused_by congenital abnormalities in the lymphatic system.", "url": "https://disease-ontology.org/term/DOID:0050580", "evidence": [ { "id": "0050580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050580" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" }, { "name": "somitogenesis", "id": "GO:0001756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001756", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" }, { "name": "artery morphogenesis", "id": "GO:0048844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048844", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" }, { "name": "chloride ion homeostasis", "id": "GO:0055064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055064", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcitonin receptor activity", "id": "GO:0004948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004948", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" }, { "name": "adrenomedullin receptor activity", "id": "GO:0001605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001605", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" }, { "name": "calcitonin gene-related peptide receptor activity", "id": "GO:0001635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001635", "evidence": [ { "database": "UniProtKB", "id": "Q68EK2", "url": "https://www.uniprot.org/uniprotkb/Q68EK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q68EK2-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Asn126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 126, "start_aa": "Asn", "end_pos": 126, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn126", "evidence": [ { "id": "Q68EK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68EK2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q68EK2-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Asn131", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 131, "start_aa": "Asn", "end_pos": 131, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn131", "evidence": [ { "id": "Q68EK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68EK2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q68EK2-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Asn28", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 28, "start_aa": "Asn", "end_pos": 28, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn28", "evidence": [ { "id": "Q68EK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68EK2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q68EK2-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Asn295", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 295, "start_aa": "Asn", "end_pos": 295, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn295", "evidence": [ { "id": "Q68EK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68EK2#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q68EK2-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Asn74", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 74, "start_aa": "Asn", "end_pos": 74, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn74", "evidence": [ { "id": "Q68EK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q68EK2#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q68EK7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 213, "chemical_mass": 23725.0, "gene_names": "rab4b;rab4b;zgc:101015", "protein_name": "Ras-related protein Rab-4B", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "insulin-responsive compartment", "id": "GO:0032593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032593", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "Q68EK7", "url": "https://www.uniprot.org/uniprotkb/Q68EK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q68EL2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68EL2", "url": "https://www.uniprot.org/uniprotkb/Q68EL2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 160, "chemical_mass": 17847.0, "gene_names": "dtd2;zgc:100795", "protein_name": "D-aminoacyl-tRNA deacylase 2", "disease": [], "biological_process": [ { "name": "tRNA metabolic process", "id": "GO:0006399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006399", "evidence": [ { "database": "UniProtKB", "id": "Q68EL2", "url": "https://www.uniprot.org/uniprotkb/Q68EL2" } ], "pmid": "" }, { "name": "aminoacyl-tRNA metabolism involved in translational fidelity", "id": "GO:0106074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106074", "evidence": [ { "database": "UniProtKB", "id": "Q68EL2", "url": "https://www.uniprot.org/uniprotkb/Q68EL2" } ], "pmid": "" } ], "molecular_function": [ { "name": "D-tyrosyl-tRNA(Tyr) deacylase activity", "id": "GO:0051500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051500", "evidence": [ { "database": "UniProtKB", "id": "Q68EL2", "url": "https://www.uniprot.org/uniprotkb/Q68EL2" } ], "pmid": "" }, { "name": "Ala-tRNA(Thr) deacylase activity", "id": "GO:0106105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106105", "evidence": [ { "database": "UniProtKB", "id": "Q68EL2", "url": "https://www.uniprot.org/uniprotkb/Q68EL2" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "Q68EL2", "url": "https://www.uniprot.org/uniprotkb/Q68EL2" } ], "pmid": "" }, { "name": "Gly-tRNA(Ala) deacylase activity", "id": "GO:0106026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106026", "evidence": [ { "database": "UniProtKB", "id": "Q68EL2", "url": "https://www.uniprot.org/uniprotkb/Q68EL2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q68EL2", "url": "https://www.uniprot.org/uniprotkb/Q68EL2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q68FN7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q68FN7", "url": "https://www.uniprot.org/uniprotkb/Q68FN7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 158, "chemical_mass": 16973.0, "gene_names": "sdhdb;cybS-B;sdhda;sdhdb;sdhd;zgc:100986", "protein_name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial", "disease": [ { "disease_id": "DOID:0050773", "name": "paraganglioma", "description": "A pheochromocytoma that arises in extraadrenal sympathetic ganglia.", "url": "https://disease-ontology.org/term/DOID:0050773", "evidence": [ { "id": "0050773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050773" } ], "weight": 0.0 }, { "disease_id": "DOID:0060537", "name": "mitochondrial complex II deficiency", "description": "A mitochondrial metabolism disease characterized by a highly variable phenotype. Some patients have multisystem involvement of the brain, heart, muscle, liver, and kidneys resulting in death in infancy, whereas others have only isolated cardiac or muscle involvement with onset in adulthood and normal cognition. It has_material_basis_in homozygous or compound heterozygous mutation in the nuclear-encoded SDHA gene on chromosome 5p, the nuclear-encoded SDHAF1 gene on chromosome 19q, or the nuclear-encoded SDHD gene on chromosome 11q23.", "url": "https://disease-ontology.org/term/DOID:0060537", "evidence": [ { "id": "0060537", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060537" } ], "weight": 0.0 }, { "disease_id": "DOID:0061216", "name": "pheochromocytoma/paraganglioma syndrome 1", "description": "A paraganglioma characterized by the development of neuroendocrine tumors, usually in adulthood that has material_basis_in heterozygous mutation in the SDHD gene.", "url": "https://disease-ontology.org/term/DOID:0061216", "evidence": [ { "id": "0061216", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061216" } ], "weight": 0.0 }, { "disease_id": "DOID:0080533", "name": "Carney-Stratakis syndrome", "description": "A syndrome that is characterized by the presence of multicentric paragangliomas and multifocal gastrointestinal stromal sarcoma tumors.", "url": "https://disease-ontology.org/term/DOID:0080533", "evidence": [ { "id": "0080533", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080533" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q68FN7", "url": "https://www.uniprot.org/uniprotkb/Q68FN7" } ], "pmid": "" }, { "name": "respiratory chain complex II (succinate dehydrogenase)", "id": "GO:0045273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045273", "evidence": [ { "database": "UniProtKB", "id": "Q68FN7", "url": "https://www.uniprot.org/uniprotkb/Q68FN7" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "Q68FN7", "url": "https://www.uniprot.org/uniprotkb/Q68FN7" } ], "pmid": "" }, { "name": "mitochondrial electron transport, succinate to ubiquinone", "id": "GO:0006121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006121", "evidence": [ { "database": "UniProtKB", "id": "Q68FN7", "url": "https://www.uniprot.org/uniprotkb/Q68FN7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q68FN7", "url": "https://www.uniprot.org/uniprotkb/Q68FN7" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q68FN7", "url": "https://www.uniprot.org/uniprotkb/Q68FN7" } ], "pmid": "" }, { "name": "ubiquinone binding", "id": "GO:0048039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048039", "evidence": [ { "database": "UniProtKB", "id": "Q68FN7", "url": "https://www.uniprot.org/uniprotkb/Q68FN7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q696W0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q696W0", "url": "https://www.uniprot.org/uniprotkb/Q696W0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2995, "chemical_mass": 333684.0, "gene_names": "speg;apeg1", "protein_name": "Striated muscle preferentially expressed protein kinase", "disease": [ { "disease_id": "DOID:0111222", "name": "centronuclear myopathy 5", "description": "An autosomal recessive centronuclear myopathy characterized by severe neonatal hypotonia, respiratory insufficiency, and difficulty feeding that has_material_basis_in homozygous or compound heterozygous mutation in SPEG on 2q35.", "url": "https://disease-ontology.org/term/DOID:0111222", "evidence": [ { "id": "0111222", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111222" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q696W0", "url": "https://www.uniprot.org/uniprotkb/Q696W0" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q696W0", "url": "https://www.uniprot.org/uniprotkb/Q696W0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q696W0", "url": "https://www.uniprot.org/uniprotkb/Q696W0" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q696W0", "url": "https://www.uniprot.org/uniprotkb/Q696W0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q696W0", "url": "https://www.uniprot.org/uniprotkb/Q696W0" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "Q696W0", "url": "https://www.uniprot.org/uniprotkb/Q696W0" } ], "pmid": "" } ], "biological_process": [ { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "Q696W0", "url": "https://www.uniprot.org/uniprotkb/Q696W0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q696W0-1", "start_pos": "1958", "end_pos": "1958", "site_lbl": "Thr1958", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1958, "start_aa": "Thr", "end_pos": 1958, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1958", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q696W0-1", "start_pos": "1971", "end_pos": "1971", "site_lbl": "Thr1971", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1971, "start_aa": "Thr", "end_pos": 1971, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1971", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q696W0-1", "start_pos": "2556", "end_pos": "2556", "site_lbl": "Thr2556", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2556, "start_aa": "Thr", "end_pos": 2556, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2556", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q696W0-1", "start_pos": "2655", "end_pos": "2655", "site_lbl": "Thr2655", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2655, "start_aa": "Thr", "end_pos": 2655, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2655", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6AXJ2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 335, "chemical_mass": 38597.0, "gene_names": "eif3ha;eIF3h-A;eif3ha;eif3h;eif3s3a;eif3s3;fj02c04;wu:fj02c04;zgc:101085", "protein_name": "Eukaryotic translation initiation factor 3 subunit H-A", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10286", "name": "prostate carcinoma", "description": "A prostate cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:10286", "evidence": [ { "id": "10286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10286" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" }, { "name": "lateral line development", "id": "GO:0048882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048882", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q6AXJ2", "url": "https://www.uniprot.org/uniprotkb/Q6AXJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6AXK4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 370, "chemical_mass": 40901.0, "gene_names": "babam1;Zgc:100909;babam1;merit40;nba1;zgc:100909", "protein_name": "BRISC and BRCA1-A complex member 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "BRISC complex", "id": "GO:0070552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070552", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "BRCA1-A complex", "id": "GO:0070531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070531", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" }, { "name": "DNA repair-dependent chromatin remodeling", "id": "GO:0140861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140861", "evidence": [ { "database": "UniProtKB", "id": "Q6AXK4", "url": "https://www.uniprot.org/uniprotkb/Q6AXK4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6AXL3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 685, "chemical_mass": 77765.0, "gene_names": "nrros;lrrc33;nrros;zgc:100989", "protein_name": "Transforming growth factor beta activator LRRC33", "disease": [], "biological_process": [ { "name": "sequestering of TGFbeta in extracellular matrix", "id": "GO:0035583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035583", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "microglia development", "id": "GO:0014005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014005", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" } ], "molecular_function": [ { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" }, { "name": "receptor ligand inhibitor activity", "id": "GO:0141069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141069", "evidence": [ { "database": "UniProtKB", "id": "Q6AXL3", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "154", "end_pos": "154", "site_lbl": "Asn154", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 154, "start_aa": "Asn", "end_pos": 154, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn154", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Asn230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 230, "start_aa": "Asn", "end_pos": 230, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn230", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Asn244", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 244, "start_aa": "Asn", "end_pos": 244, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn244", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Asn291", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 291, "start_aa": "Asn", "end_pos": 291, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn291", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "296", "end_pos": "296", "site_lbl": "Asn296", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 296, "start_aa": "Asn", "end_pos": 296, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn296", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "309", "end_pos": "309", "site_lbl": "Asn309", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 309, "start_aa": "Asn", "end_pos": 309, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn309", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Asn312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 312, "start_aa": "Asn", "end_pos": 312, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn312", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Asn325", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Asn402", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 402, "start_aa": "Asn", "end_pos": 402, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn402", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "407", "end_pos": "407", "site_lbl": "Asn407", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 407, "start_aa": "Asn", "end_pos": 407, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn407", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6AXL3-1", "start_pos": "533", "end_pos": "533", "site_lbl": "Asn533", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 533, "start_aa": "Asn", "end_pos": 533, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn533", "evidence": [ { "id": "Q6AXL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6AXL3#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6AZW2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 324, "chemical_mass": 36762.0, "gene_names": "akr1a1a;akr1a1a;akr1a1;si:ch211-113n10.1;zgc:100940", "protein_name": "Aldo-keto reductase family 1 member A1-A", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "aldose reductase (NADPH) activity", "id": "GO:0004032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004032", "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "pmid": "" }, { "name": "S-nitrosoglutathione reductase (NADPH) activity", "id": "GO:0160163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160163", "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "pmid": "" } ], "biological_process": [ { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "pmid": "" }, { "name": "aldehyde catabolic process", "id": "GO:0046185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046185", "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "pmid": "" }, { "name": "cellular detoxification of aldehyde", "id": "GO:0110095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110095", "evidence": [ { "database": "UniProtKB", "id": "Q6AZW2", "url": "https://www.uniprot.org/uniprotkb/Q6AZW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6AZW2-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Thr221", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6B3P0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 857, "chemical_mass": 95169.0, "gene_names": "cdhr1a;cdhr1a;cdhr1;pcdh21;prcad", "protein_name": "Cadherin-related family member 1a", "disease": [ { "disease_id": "DOID:0111021", "name": "cone-rod dystrophy 15", "description": "A cone-rod dystrophy that has_material_basis_in homozygous mutation in the CDHR1 gene on chromosome 10q23.", "url": "https://disease-ontology.org/term/DOID:0111021", "evidence": [ { "id": "0111021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111021" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glial cell development", "id": "GO:0021782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021782", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" }, { "name": "retina layer formation", "id": "GO:0010842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010842", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" }, { "name": "photoreceptor cell development", "id": "GO:0042461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042461", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "Q6B3P0", "url": "https://www.uniprot.org/uniprotkb/Q6B3P0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6BEA0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1903, "chemical_mass": 213792.0, "gene_names": "plxna4;D204;plxna4;wu:fd49b01;wu:fe15f03", "protein_name": "Plexin-A4", "disease": [], "cellular_component": [ { "name": "semaphorin receptor complex", "id": "GO:0002116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002116", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" } ], "biological_process": [ { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" }, { "name": "morphogenesis of a branching structure", "id": "GO:0001763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001763", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" }, { "name": "axonal defasciculation", "id": "GO:0007414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007414", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" } ], "molecular_function": [ { "name": "semaphorin receptor activity", "id": "GO:0017154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017154", "evidence": [ { "database": "UniProtKB", "id": "Q6BEA0", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "1025", "end_pos": "1025", "site_lbl": "Asn1025", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1025, "start_aa": "Asn", "end_pos": 1025, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1025", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "1141", "end_pos": "1141", "site_lbl": "Asn1141", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1141, "start_aa": "Asn", "end_pos": 1141, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1141", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "1181", "end_pos": "1181", "site_lbl": "Thr1181", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1181, "start_aa": "Thr", "end_pos": 1181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1181", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "1189", "end_pos": "1189", "site_lbl": "Asn1189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1189, "start_aa": "Asn", "end_pos": 1189, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1189", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "1214", "end_pos": "1214", "site_lbl": "Asn1214", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1214, "start_aa": "Asn", "end_pos": 1214, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1214", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Asn166", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 166, "start_aa": "Asn", "end_pos": 166, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn166", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 271, "start_aa": "Thr", "end_pos": 271, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr271", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Asn450", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 450, "start_aa": "Asn", "end_pos": 450, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn450", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "575", "end_pos": "575", "site_lbl": "Asn575", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 575, "start_aa": "Asn", "end_pos": 575, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn575", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "600", "end_pos": "600", "site_lbl": "Asn600", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 600, "start_aa": "Asn", "end_pos": 600, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn600", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "656", "end_pos": "656", "site_lbl": "Asn656", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 656, "start_aa": "Asn", "end_pos": 656, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn656", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "663", "end_pos": "663", "site_lbl": "Asn663", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 663, "start_aa": "Asn", "end_pos": 663, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn663", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "764", "end_pos": "764", "site_lbl": "Asn764", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 764, "start_aa": "Asn", "end_pos": 764, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn764", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "772", "end_pos": "772", "site_lbl": "Asn772", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 772, "start_aa": "Asn", "end_pos": 772, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn772", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "981", "end_pos": "981", "site_lbl": "Asn981", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 981, "start_aa": "Asn", "end_pos": 981, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn981", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6BEA0-1", "start_pos": "992", "end_pos": "992", "site_lbl": "Asn992", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 992, "start_aa": "Asn", "end_pos": 992, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn992", "evidence": [ { "id": "Q6BEA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6BEA0#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DBQ8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 211, "chemical_mass": 23993.0, "gene_names": "cptp;cptp;fb75f03;gltpd1;wu:fb75f03;zgc:92000", "protein_name": "Ceramide-1-phosphate transfer protein", "disease": [], "molecular_function": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "ceramide 1-phosphate binding", "id": "GO:1902387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902387", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "ceramide 1-phosphate transfer activity", "id": "GO:1902388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902388", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide transport", "id": "GO:0035627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035627", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "ceramide 1-phosphate transport", "id": "GO:1902389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902389", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" }, { "name": "negative regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900226", "evidence": [ { "database": "UniProtKB", "id": "Q6DBQ8", "url": "https://www.uniprot.org/uniprotkb/Q6DBQ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DBW0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 419, "chemical_mass": 46155.0, "gene_names": "ikzf5;ikzf5;wu:fb55f09;zgc:92405", "protein_name": "Zinc finger protein Pegasus", "disease": [ { "disease_id": "DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood.", "url": "https://disease-ontology.org/term/DOID:1588", "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ], "weight": 0.0 } ], "biological_process": [ { "name": "determination of left/right asymmetry in lateral mesoderm", "id": "GO:0003140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003140", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" }, { "name": "determination of pancreatic left/right asymmetry", "id": "GO:0035469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035469", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" }, { "name": "determination of intestine left/right asymmetry", "id": "GO:0071908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071908", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DBW0", "url": "https://www.uniprot.org/uniprotkb/Q6DBW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DBW0-1", "start_pos": "357", "end_pos": "357", "site_lbl": "Thr357", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 357, "start_aa": "Thr", "end_pos": 357, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr357", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DC39-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DC39", "url": "https://www.uniprot.org/uniprotkb/Q6DC39" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 196, "chemical_mass": 21859.0, "gene_names": "desi2;DeSI-2;cb238;desi1;desi2;fam152a;fi12d12;pppde1;sb:cb238;si:ch211-132e22.3;wu:fi12d12;zgc:100860", "protein_name": "Deubiquitinase DESI2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DC39", "url": "https://www.uniprot.org/uniprotkb/Q6DC39" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q6DC39", "url": "https://www.uniprot.org/uniprotkb/Q6DC39" } ], "pmid": "" }, { "name": "convergent extension involved in gastrulation", "id": "GO:0060027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060027", "evidence": [ { "database": "UniProtKB", "id": "Q6DC39", "url": "https://www.uniprot.org/uniprotkb/Q6DC39" } ], "pmid": "" } ], "molecular_function": [ { "name": "palmitoyl-(protein) hydrolase activity", "id": "GO:0008474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008474", "evidence": [ { "database": "UniProtKB", "id": "Q6DC39", "url": "https://www.uniprot.org/uniprotkb/Q6DC39" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "Q6DC39", "url": "https://www.uniprot.org/uniprotkb/Q6DC39" } ], "pmid": "" }, { "name": "long-chain fatty acyl-CoA hydrolase activity", "id": "GO:0052816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052816", "evidence": [ { "database": "UniProtKB", "id": "Q6DC39", "url": "https://www.uniprot.org/uniprotkb/Q6DC39" } ], "pmid": "" }, { "name": "deubiquitinase activity", "id": "GO:0101005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101005", "evidence": [ { "database": "UniProtKB", "id": "Q6DC39", "url": "https://www.uniprot.org/uniprotkb/Q6DC39" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DC93-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 270, "chemical_mass": 29425.0, "gene_names": "pef1;pef1;zgc:100787", "protein_name": "Peflin", "disease": [], "biological_process": [ { "name": "neural crest formation", "id": "GO:0014029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014029", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" }, { "name": "neural crest cell development", "id": "GO:0014032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014032", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" }, { "name": "COPII vesicle coating", "id": "GO:0048208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048208", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" }, { "name": "positive regulation of protein monoubiquitination", "id": "GO:1902527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902527", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "Q6DC93", "url": "https://www.uniprot.org/uniprotkb/Q6DC93" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DG22-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 359, "chemical_mass": 40844.0, "gene_names": "ada;ada;zgc:92028", "protein_name": "Adenosine deaminase", "disease": [ { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:10113", "name": "trypanosomiasis", "description": "A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans.", "url": "https://disease-ontology.org/term/DOID:10113", "evidence": [ { "id": "10113", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10113" } ], "weight": 0.0 }, { "disease_id": "DOID:10457", "name": "Legionnaires' disease", "description": "A legionellosis that is characterized by severe form of infection producing pneumonia. Symptoms include fever, chills, and cough.", "url": "https://disease-ontology.org/term/DOID:10457", "evidence": [ { "id": "10457", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10457" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:106", "name": "pleural tuberculosis", "description": "An extrapulmonary tuberculosis that results_in lymphocyte-predominant exudative pleural effusion, located_in pleura. This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac.", "url": "https://disease-ontology.org/term/DOID:106", "evidence": [ { "id": "106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:106" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10808", "name": "gastric ulcer", "description": "", "url": "https://disease-ontology.org/term/DOID:10808", "evidence": [ { "id": "10808", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10808" } ], "weight": 0.0 }, { "disease_id": "DOID:11100", "name": "Q fever", "description": "A primary bacterial infectious disease that is a zoonotic infectious disease affecting multiple organs, has_material_basis_in Coxiella burnetii, which is transmitted_by inhalation of air contaminated by barnyard dust containing dried placental material, birth fluids, or excreta of infected herd animals, transmitted_by ingestion of contaminated milk, transmitted_by tick bites and transmitted_by contact with infected person. The infection has_symptom fever, has_symptom headache, has_symptom cough, has_symptom pleuritic chest pain, has_symptom myalgia and has_symptom arthralgia.", "url": "https://disease-ontology.org/term/DOID:11100", "evidence": [ { "id": "11100", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11100" } ], "weight": 0.0 }, { "disease_id": "DOID:11396", "name": "pulmonary edema", "description": "A respiratory failure that is characterized by the accumulation of fluid in the lung tissues causing disturbance of the gas exchange that may lead to respiratory failure.", "url": "https://disease-ontology.org/term/DOID:11396", "evidence": [ { "id": "11396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11396" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:13223", "name": "uterine fibroid", "description": "An uterine benign neoplasm derived from the smooth muscle layer of the uterus.", "url": "https://disease-ontology.org/term/DOID:13223", "evidence": [ { "id": "13223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13223" } ], "weight": 0.0 }, { "disease_id": "DOID:13276", "name": "Mycoplasma pneumoniae pneumonia", "description": "A bacterial pneumonia that is caused by the bacterial species Mycoplasma pneumoniae. The symptoms include chest pain, chills, dry cough which is not bloody, excessive sweating, fever, headache and sore throat.", "url": "https://disease-ontology.org/term/DOID:13276", "evidence": [ { "id": "13276", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13276" } ], "weight": 0.0 }, { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:14484", "name": "sporotrichosis", "description": "A primary systemic mycosis that results_in a systemic fungal infection, has_material_basis_in Sporothrix schenckii in animals and humans and results_in_formation_of red papule at the site of inoculation.", "url": "https://disease-ontology.org/term/DOID:14484", "evidence": [ { "id": "14484", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14484" } ], "weight": 0.0 }, { "disease_id": "DOID:1790", "name": "malignant mesothelioma", "description": "A cell type cancer that has_material_basis_in mesothelial tissue that develops from the thin layer of tissue that covers many of the internal organs. Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.", "url": "https://disease-ontology.org/term/DOID:1790", "evidence": [ { "id": "1790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1790" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:2297", "name": "leptospirosis", "description": "A primary bacterial infectious disease that involves systemic infection, has_material_basis_in Leptospira, which is transmitted by contact with water, food, or soil containing urine from the infected animals. The infection has symptom jaundice, has symptom chills, has symptom fever, has symptom muscle pain, and has symptom hepatomegaly.", "url": "https://disease-ontology.org/term/DOID:2297", "evidence": [ { "id": "2297", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2297" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2876", "name": "laryngeal squamous cell carcinoma", "description": "A laryngeal carcinoma that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:2876", "evidence": [ { "id": "2876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2876" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:5810", "name": "adenosine deaminase deficiency", "description": "A severe combined immunodeficiency that is caused by a defective enzyme, adenosine deaminase (ADA), necessary for the breakdown of purines. Lack of ADA causes accumulation of dATP.", "url": "https://disease-ontology.org/term/DOID:5810", "evidence": [ { "id": "5810", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5810" } ], "weight": 0.0 }, { "disease_id": "DOID:627", "name": "severe combined immunodeficiency", "description": "A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems.", "url": "https://disease-ontology.org/term/DOID:627", "evidence": [ { "id": "627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:627" } ], "weight": 0.0 }, { "disease_id": "DOID:8283", "name": "peritonitis", "description": "A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.", "url": "https://disease-ontology.org/term/DOID:8283", "evidence": [ { "id": "8283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8283" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 }, { "disease_id": "DOID:8618", "name": "oral cavity cancer", "description": "A gastrointestinal system cancer that is located_in the oral cavity.", "url": "https://disease-ontology.org/term/DOID:8618", "evidence": [ { "id": "8618", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8618" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenosine deaminase activity", "id": "GO:0004000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004000", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "2'-deoxyadenosine deaminase activity", "id": "GO:0046936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046936", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "cytoplasmic vesicle lumen", "id": "GO:0060205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060205", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" } ], "biological_process": [ { "name": "adenosine catabolic process", "id": "GO:0006154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006154", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "inosine biosynthetic process", "id": "GO:0046103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046103", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "purine ribonucleoside monophosphate biosynthetic process", "id": "GO:0009168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009168", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "hypoxanthine salvage", "id": "GO:0043103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043103", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" }, { "name": "negative regulation of adenosine receptor signaling pathway", "id": "GO:0060169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060169", "evidence": [ { "database": "UniProtKB", "id": "Q6DG22", "url": "https://www.uniprot.org/uniprotkb/Q6DG22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DG60-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DG60", "url": "https://www.uniprot.org/uniprotkb/Q6DG60" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 328, "chemical_mass": 36451.0, "gene_names": "ube2z;zgc:92419", "protein_name": "Ubiquitin-conjugating enzyme E2 Z", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6DG60", "url": "https://www.uniprot.org/uniprotkb/Q6DG60" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "Q6DG60", "url": "https://www.uniprot.org/uniprotkb/Q6DG60" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DG60", "url": "https://www.uniprot.org/uniprotkb/Q6DG60" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DG60", "url": "https://www.uniprot.org/uniprotkb/Q6DG60" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q6DG60", "url": "https://www.uniprot.org/uniprotkb/Q6DG60" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q6DG60", "url": "https://www.uniprot.org/uniprotkb/Q6DG60" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6DG60", "url": "https://www.uniprot.org/uniprotkb/Q6DG60" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DG81-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 627, "chemical_mass": 70150.0, "gene_names": "pls3;pls3;wu:fc04g03;zgc:91903", "protein_name": "Plastin-3", "disease": [ { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:3827", "name": "congenital diaphragmatic hernia", "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs.", "url": "https://disease-ontology.org/term/DOID:3827", "evidence": [ { "id": "3827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3827" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "actin filament bundle", "id": "GO:0032432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032432", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "embryonic cranial skeleton morphogenesis", "id": "GO:0048701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048701", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "pronephric nephron development", "id": "GO:0039019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039019", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" }, { "name": "pronephros morphogenesis", "id": "GO:0072114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072114", "evidence": [ { "database": "UniProtKB", "id": "Q6DG81", "url": "https://www.uniprot.org/uniprotkb/Q6DG81" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DGL6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 336, "chemical_mass": 36223.0, "gene_names": "sox1a;fi38c08;fj38h03;si:dkey-58d5.1;sox1a;wu:fi38c08;wu:fj38h03;zgc:92865", "protein_name": "Transcription factor Sox-1a", "disease": [ { "disease_id": "DOID:0111779", "name": "X-linked panhypopituitarism", "description": "A combined pituitary hormone deficiency that has_material_basis_in duplications in the SOX3 gene on chromosome Xq27.1.", "url": "https://disease-ontology.org/term/DOID:0111779", "evidence": [ { "id": "0111779", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111779" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q6DGL6", "url": "https://www.uniprot.org/uniprotkb/Q6DGL6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DGU5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGU5", "url": "https://www.uniprot.org/uniprotkb/Q6DGU5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 405, "chemical_mass": 44910.0, "gene_names": "slc25a46;si:ch211-220b11.2;slc25a46;zgc:92767", "protein_name": "Mitochondrial outer membrane protein SLC25A46", "disease": [ { "disease_id": "DOID:0080068", "name": "Charcot-Marie-Tooth disease type 6", "description": "A Charcot-Marie-Tooth disease that is characterized by early-onset optic atrophy resulting in progressive visual loss and peripheral axonal sensorimotor neuropathy with highly variable age at onset and severity.", "url": "https://disease-ontology.org/term/DOID:0080068", "evidence": [ { "id": "0080068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080068" } ], "weight": 0.0 }, { "disease_id": "DOID:0112330", "name": "pontocerebellar hypoplasia type 1E", "description": "A pontocerebellar hypoplasia type 1 characterized by onset shortly after birth of severe hypotonia and respiratory insufficiency with most patients dying within weeks of birth that has_material_basis_in homozygous or compound heterozygous mutation in the SLC25A46 gene on chromosome 5q22.1.", "url": "https://disease-ontology.org/term/DOID:0112330", "evidence": [ { "id": "0112330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112330" } ], "weight": 0.0 }, { "disease_id": "DOID:870", "name": "neuropathy", "description": "A nervous system disease that is located_in nerves or nerve cells.", "url": "https://disease-ontology.org/term/DOID:870", "evidence": [ { "id": "870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:870" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitochondrial membrane fission", "id": "GO:0090149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090149", "evidence": [ { "database": "UniProtKB", "id": "Q6DGU5", "url": "https://www.uniprot.org/uniprotkb/Q6DGU5" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "Q6DGU5", "url": "https://www.uniprot.org/uniprotkb/Q6DGU5" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "Q6DGU5", "url": "https://www.uniprot.org/uniprotkb/Q6DGU5" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "Q6DGU5", "url": "https://www.uniprot.org/uniprotkb/Q6DGU5" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q6DGU5", "url": "https://www.uniprot.org/uniprotkb/Q6DGU5" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q6DGU5", "url": "https://www.uniprot.org/uniprotkb/Q6DGU5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DGW9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 188, "chemical_mass": 21310.0, "gene_names": "tmco1;sb:cb729;tmco1;zgc:110322;zgc:92740", "protein_name": "Calcium load-activated calcium channel", "disease": [ { "disease_id": "DOID:0081072", "name": "craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome", "description": "A syndrome that is characterized by abnormal development of the brain and structures in the face and torso including facial dysmorphism, intellectual deficit costovertebral abnormalities, and delayed development of speech and movement (motor) skills.", "url": "https://disease-ontology.org/term/DOID:0081072", "evidence": [ { "id": "0081072", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081072" } ], "weight": 0.0 }, { "disease_id": "DOID:0081124", "name": "craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 1", "description": "A craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome that is characterized by cranial involvement with macrocrania at birth, brachycephaly, anomalies of middle fossa structures including hypoplasia of corpus callosum, enlargement of septum pellucidum, and dilated lateral ventricles, as well as cortical atrophy and hypodensity of the gray matter and that has_material_basis_in homozygous mutation in the TMCO1 gene on chromosome 1q24.", "url": "https://disease-ontology.org/term/DOID:0081124", "evidence": [ { "id": "0081124", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081124" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" }, { "name": "multi-pass translocon complex", "id": "GO:0160064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160064", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" }, { "name": "ER overload response", "id": "GO:0006983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006983", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" }, { "name": "endoplasmic reticulum calcium ion homeostasis", "id": "GO:0032469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032469", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" }, { "name": "multi-pass transmembrane protein insertion into ER membrane", "id": "GO:0160063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160063", "evidence": [ { "database": "UniProtKB", "id": "Q6DGW9", "url": "https://www.uniprot.org/uniprotkb/Q6DGW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DH94-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 293, "chemical_mass": 32916.0, "gene_names": "rnf144ab;rnf144ab;rnf144a;rnf144;si:dkeyp-7f8.1-001;si:dkeyp-7f8.1;wu:fj49a04;zgc:92582", "protein_name": "Probable E3 ubiquitin-protein ligase RNF144A-B", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q6DH94", "url": "https://www.uniprot.org/uniprotkb/Q6DH94" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHE8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 193, "chemical_mass": 21993.0, "gene_names": "rhoad;rhoad;rhocb;zgc:92350", "protein_name": "Rho-related GTP-binding protein RhoA-D", "disease": [ { "disease_id": "DOID:0050665", "name": "fetal alcohol syndrome", "description": "A fetal alcohol spectrum disorder that results in severe mental and physical defects which can develop in a child when the mother drinks alcohol during pregnancy. The presenting features include craniofacial dysmorphology (microcephaly, smooth philtrum, thin upper lip, small eye openings), pre- and postnatal growth deficiency, and central nervous system dysfunction.", "url": "https://disease-ontology.org/term/DOID:0050665", "evidence": [ { "id": "0050665", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050665" } ], "weight": 0.0 }, { "disease_id": "DOID:0080377", "name": "peroxisomal biogenesis disorder", "description": "A peroxisomal biogenesis disorder that has_material_basis_in defects in PEX genes.", "url": "https://disease-ontology.org/term/DOID:0080377", "evidence": [ { "id": "0080377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080377" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:4001", "name": "ovarian carcinoma", "description": "An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:4001", "evidence": [ { "id": "4001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4001" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9408", "name": "acute myocardial infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:9408", "evidence": [ { "id": "9408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9408" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" } ], "biological_process": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "skeletal muscle satellite cell migration", "id": "GO:1902766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902766", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" }, { "name": "wound healing, spreading of cells", "id": "GO:0044319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044319", "evidence": [ { "database": "UniProtKB", "id": "Q6DHE8", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DHE8-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Tyr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "Y", "relation": "attached", "comment": "O-linked (GlcNAc) tyrosine;O-GlcNAcylation", "icn3d_view": {}, "start_pos": 34, "start_aa": "Tyr", "end_pos": 34, "end_aa": "Tyr", "residue": "Tyr", "site_lbl": "Tyr34", "evidence": [ { "id": "Q6DHE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DHE8#ptm_processing" }, { "id": "26190758", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26190758" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHG0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 373, "chemical_mass": 41512.0, "gene_names": "setd7;set7;setd7;zgc:101860;zgc:92330", "protein_name": "Histone-lysine N-methyltransferase SETD7", "disease": [ { "disease_id": "DOID:0050696", "name": "fetal alcohol spectrum disorder", "description": "A specific developmental disorder and physical disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of alcohol during pregnancy.", "url": "https://disease-ontology.org/term/DOID:0050696", "evidence": [ { "id": "0050696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050696" } ], "weight": 0.0 }, { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "peptidyl-lysine monomethylation", "id": "GO:0018026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018026", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "peptidyl-lysine dimethylation", "id": "GO:0018027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018027", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "histone H3K4 monomethyltransferase activity", "id": "GO:0140945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140945", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" }, { "name": "histone H3 methyltransferase activity", "id": "GO:0140938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140938", "evidence": [ { "database": "UniProtKB", "id": "Q6DHG0", "url": "https://www.uniprot.org/uniprotkb/Q6DHG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHI2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHI2", "url": "https://www.uniprot.org/uniprotkb/Q6DHI2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 492, "chemical_mass": 57703.0, "gene_names": "drc2;NYD-SP28;ccdc65;drc2;si:busm1-202l16.3;si:dz202l16.3;zgc:92302", "protein_name": "Dynein regulatory complex subunit 2", "disease": [ { "disease_id": "DOID:0110611", "name": "primary ciliary dyskinesia 27", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with neonatal respiratory distress, recurrent upper and lower airway disease, and bronchiectasis and has_material_basis_in homozygous mutation in the CCDC65 gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0110611", "evidence": [ { "id": "0110611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110611" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI2", "url": "https://www.uniprot.org/uniprotkb/Q6DHI2" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI2", "url": "https://www.uniprot.org/uniprotkb/Q6DHI2" } ], "pmid": "" }, { "name": "axonemal dynein complex", "id": "GO:0005858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005858", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI2", "url": "https://www.uniprot.org/uniprotkb/Q6DHI2" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium-dependent cell motility", "id": "GO:0060285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060285", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI2", "url": "https://www.uniprot.org/uniprotkb/Q6DHI2" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI2", "url": "https://www.uniprot.org/uniprotkb/Q6DHI2" } ], "pmid": "" }, { "name": "regulation of cilium movement", "id": "GO:0003352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003352", "evidence": [ { "database": "UniProtKB", "id": "Q6DHI2", "url": "https://www.uniprot.org/uniprotkb/Q6DHI2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHJ3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHJ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHJ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 460, "chemical_mass": 52307.0, "gene_names": "nvd;Neverland;nvd-Dr;nvd;zgc:92275", "protein_name": "Cholesterol 7-desaturase nvd", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6DHJ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHJ3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6DHJ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHJ3" } ], "pmid": "" } ], "biological_process": [ { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "Q6DHJ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHJ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6DHJ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHJ3" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q6DHJ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHJ3" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q6DHJ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHJ3" } ], "pmid": "" }, { "name": "cholesterol 7-desaturase [NAD(P)H] activity", "id": "GO:0170056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170056", "evidence": [ { "database": "UniProtKB", "id": "Q6DHJ3", "url": "https://www.uniprot.org/uniprotkb/Q6DHJ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHK1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHK1", "url": "https://www.uniprot.org/uniprotkb/Q6DHK1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 283, "chemical_mass": 30882.0, "gene_names": "naxe;AIBP;APOA1BP;aibp;apoa1bp;naxe;si:dkeyp-84f11.6;zgc:92263", "protein_name": "NAD(P)H-hydrate epimerase", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK1", "url": "https://www.uniprot.org/uniprotkb/Q6DHK1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK1", "url": "https://www.uniprot.org/uniprotkb/Q6DHK1" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK1", "url": "https://www.uniprot.org/uniprotkb/Q6DHK1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK1", "url": "https://www.uniprot.org/uniprotkb/Q6DHK1" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK1", "url": "https://www.uniprot.org/uniprotkb/Q6DHK1" } ], "pmid": "" }, { "name": "NAD(P)HX epimerase activity", "id": "GO:0052856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052856", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK1", "url": "https://www.uniprot.org/uniprotkb/Q6DHK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHK8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHK8", "url": "https://www.uniprot.org/uniprotkb/Q6DHK8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 336, "chemical_mass": 36838.0, "gene_names": "slc10a7;slc10a7;zgc:92251", "protein_name": "Sodium/bile acid cotransporter 7", "disease": [ { "disease_id": "DOID:225", "name": "syndrome", "description": "A disease characterized by a group of signs and symptoms that occur together and characterize a particular abnormality.", "url": "https://disease-ontology.org/term/DOID:225", "evidence": [ { "id": "225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:225" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK8", "url": "https://www.uniprot.org/uniprotkb/Q6DHK8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK8", "url": "https://www.uniprot.org/uniprotkb/Q6DHK8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK8", "url": "https://www.uniprot.org/uniprotkb/Q6DHK8" } ], "pmid": "" } ], "molecular_function": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK8", "url": "https://www.uniprot.org/uniprotkb/Q6DHK8" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK8", "url": "https://www.uniprot.org/uniprotkb/Q6DHK8" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK8", "url": "https://www.uniprot.org/uniprotkb/Q6DHK8" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "Q6DHK8", "url": "https://www.uniprot.org/uniprotkb/Q6DHK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHQ1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 235, "chemical_mass": 27110.0, "gene_names": "hvcn1;hvcn1;zgc:92181", "protein_name": "Voltage-gated hydrogen channel 1", "disease": [ { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "pmid": "" }, { "name": "voltage-gated proton channel activity", "id": "GO:0030171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030171", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "pmid": "" } ], "biological_process": [ { "name": "response to zinc ion", "id": "GO:0010043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010043", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "pmid": "" }, { "name": "cellular response to pH", "id": "GO:0071467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071467", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "pmid": "" }, { "name": "cellular response to zinc ion", "id": "GO:0071294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071294", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "Q6DHQ1", "url": "https://www.uniprot.org/uniprotkb/Q6DHQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHR0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 261, "chemical_mass": 29050.0, "gene_names": "rspo1;fj81e05;rspo1;wu:fj81e05;zgc:92153", "protein_name": "R-spondin-1", "disease": [ { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" }, { "name": "hematopoietic stem cell differentiation", "id": "GO:0060218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6DHR0", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DHR0-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Asn137", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 137, "start_aa": "Asn", "end_pos": 137, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn137", "evidence": [ { "id": "Q6DHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DHR0-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Asn161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 161, "start_aa": "Asn", "end_pos": 161, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn161", "evidence": [ { "id": "Q6DHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DHR0-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Asn170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 170, "start_aa": "Asn", "end_pos": 170, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn170", "evidence": [ { "id": "Q6DHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DHR0-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Asn247", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 247, "start_aa": "Asn", "end_pos": 247, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn247", "evidence": [ { "id": "Q6DHR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DHR0#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHU1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHU1", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 538, "chemical_mass": 62497.0, "gene_names": "clptm1l;CRR9p;clptm1l;zgc:92063", "protein_name": "Lipid scramblase CLPTM1L", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0050921", "name": "pharynx squamous cell carcinoma", "description": "A pharynx cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050921", "evidence": [ { "id": "0050921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050921" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4948", "name": "gallbladder carcinoma", "description": "A gallbladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4948", "evidence": [ { "id": "4948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4948" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 }, { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU1", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU1", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU1", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU1", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU1", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DHU1-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Asn100", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 100, "start_aa": "Asn", "end_pos": 100, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn100", "evidence": [ { "id": "Q6DHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DHU1-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Asn229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 229, "start_aa": "Asn", "end_pos": 229, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn229", "evidence": [ { "id": "Q6DHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6DHU1-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Asn90", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 90, "start_aa": "Asn", "end_pos": 90, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn90", "evidence": [ { "id": "Q6DHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6DHU1#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DHU8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DHU8", "url": "https://www.uniprot.org/uniprotkb/Q6DHU8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 339, "chemical_mass": 37664.0, "gene_names": "pbk;pbk;topk;zgc:92050", "protein_name": "Lymphokine-activated killer T-cell-originated protein kinase homolog", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU8", "url": "https://www.uniprot.org/uniprotkb/Q6DHU8" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU8", "url": "https://www.uniprot.org/uniprotkb/Q6DHU8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU8", "url": "https://www.uniprot.org/uniprotkb/Q6DHU8" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU8", "url": "https://www.uniprot.org/uniprotkb/Q6DHU8" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU8", "url": "https://www.uniprot.org/uniprotkb/Q6DHU8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DHU8-1", "start_pos": "203", "end_pos": "203", "site_lbl": "Ser203", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6DHU8", "url": "https://www.uniprot.org/uniprotkb/Q6DHU8" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DRD9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRD9", "url": "https://www.uniprot.org/uniprotkb/Q6DRD9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 317, "chemical_mass": 34924.0, "gene_names": "abhd11;Wbscr21l;abhd11;wbscr21", "protein_name": "sn-1-specific diacylglycerol lipase ABHD11", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6DRD9", "url": "https://www.uniprot.org/uniprotkb/Q6DRD9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q6DRD9", "url": "https://www.uniprot.org/uniprotkb/Q6DRD9" } ], "pmid": "" }, { "name": "oxoglutarate dehydrogenase complex", "id": "GO:0045252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045252", "evidence": [ { "database": "UniProtKB", "id": "Q6DRD9", "url": "https://www.uniprot.org/uniprotkb/Q6DRD9" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q6DRD9", "url": "https://www.uniprot.org/uniprotkb/Q6DRD9" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q6DRD9", "url": "https://www.uniprot.org/uniprotkb/Q6DRD9" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "Q6DRD9", "url": "https://www.uniprot.org/uniprotkb/Q6DRD9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DRI1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 446, "chemical_mass": 52389.0, "gene_names": "eif3ea;eIF3-p48;eif3ea;eif3s6a;eif3s6;fc55e01;int6;wu:fc55e01;zgc:63821", "protein_name": "Eukaryotic translation initiation factor 3 subunit E-A", "disease": [ { "disease_id": "DOID:3669", "name": "intermittent claudication", "description": "", "url": "https://disease-ontology.org/term/DOID:3669", "evidence": [ { "id": "3669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3669" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "pmid": "" }, { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex, eIF3e", "id": "GO:0071540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071540", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "pmid": "" } ], "biological_process": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q6DRI1", "url": "https://www.uniprot.org/uniprotkb/Q6DRI1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DRL4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1824, "chemical_mass": 201945.0, "gene_names": "ticrr;ticrr", "protein_name": "Treslin", "disease": [], "biological_process": [ { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DRL4", "url": "https://www.uniprot.org/uniprotkb/Q6DRL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DRL4-1", "start_pos": "1212", "end_pos": "1212", "site_lbl": "Thr1212", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1212, "start_aa": "Thr", "end_pos": 1212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1212", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6DRL4-1", "start_pos": "1598", "end_pos": "1598", "site_lbl": "Thr1598", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1598, "start_aa": "Thr", "end_pos": 1598, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1598", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6DRL4-1", "start_pos": "1644", "end_pos": "1644", "site_lbl": "Thr1644", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1644, "start_aa": "Thr", "end_pos": 1644, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1644", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DRM0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 170, "chemical_mass": 19219.0, "gene_names": "get1;get1;pwi;wrb;wu:ft06h05;zgc:101856", "protein_name": "Guided entry of tail-anchored proteins factor 1", "disease": [], "biological_process": [ { "name": "startle response", "id": "GO:0001964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001964", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" }, { "name": "response to auditory stimulus", "id": "GO:0010996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010996", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" }, { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" }, { "name": "GET complex", "id": "GO:0043529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043529", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "Q6DRM0", "url": "https://www.uniprot.org/uniprotkb/Q6DRM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6DRP2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 561, "chemical_mass": 62901.0, "gene_names": "gnl3;gnl3;id:ibd2914;nstm;wu:fb38a04;wu:fc55d07;zgc:123093", "protein_name": "Guanine nucleotide-binding protein-like 3", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "neural retina development", "id": "GO:0003407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003407", "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "pmid": "" }, { "name": "regulation of exit from mitosis", "id": "GO:0007096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007096", "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "pmid": "" }, { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6DRP2", "url": "https://www.uniprot.org/uniprotkb/Q6DRP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6DRP2-1", "start_pos": "468", "end_pos": "468", "site_lbl": "Thr468", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 468, "start_aa": "Thr", "end_pos": 468, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr468", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6GMI0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 479, "chemical_mass": 51441.0, "gene_names": "htra1a;htra1a;htra1;prss11;zgc:92029", "protein_name": "Serine protease HTRA1A", "disease": [ { "disease_id": "DOID:0050661", "name": "vitelliform macular dystrophy", "description": "A macular degeneration that it is characterized by the disruption of cells in a small area near the center of the retina, the macula and may cause progressive vision loss.", "url": "https://disease-ontology.org/term/DOID:0050661", "evidence": [ { "id": "0050661", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050661" } ], "weight": 0.0 }, { "disease_id": "DOID:0060863", "name": "patterned macular dystrophy", "description": "A macular degeneration characterized by abnormal accumulation of lipofuscin in the retinal pigment epithelium in a distinct pattern, patterns include; reticular ('fishnet-like'), macroreticular ('spider-shaped'), and butterfly-shaped.", "url": "https://disease-ontology.org/term/DOID:0060863", "evidence": [ { "id": "0060863", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060863" } ], "weight": 0.0 }, { "disease_id": "DOID:0061228", "name": "autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 2", "description": "A CADASIL characterized by alopecia, spondylosis, and progressive motor dysfunction and dementia. Onset is usually in the second or third decade that has_material_basis_in homozygous or compound heterozygous mutation in the HTRA1 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0061228", "evidence": [ { "id": "0061228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061228" } ], "weight": 0.0 }, { "disease_id": "DOID:0110019", "name": "age related macular degeneration 7", "description": "An age related macular degeneration conferred by variation in the HTRA1 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0110019", "evidence": [ { "id": "0110019", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110019" } ], "weight": 0.0 }, { "disease_id": "DOID:0111036", "name": "autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 2", "description": "A CADASIL characterized by stroke, transient ischemic attacks, cognitive impairment, dementia, balance impairment, gait disturbance, headaches, and/or seizures associated with early confluent or confluent diffuse white matter hyperintensities that has_material_basis_in heterozygous mutation in the HTRA1 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0111036", "evidence": [ { "id": "0111036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111036" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10871", "name": "age related macular degeneration", "description": "A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.", "url": "https://disease-ontology.org/term/DOID:10871", "evidence": [ { "id": "10871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10871" } ], "weight": 0.0 }, { "disease_id": "DOID:10873", "name": "Kuhnt-Junius degeneration", "description": "", "url": "https://disease-ontology.org/term/DOID:10873", "evidence": [ { "id": "10873", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10873" } ], "weight": 0.0 }, { "disease_id": "DOID:1107", "name": "esophageal carcinoma", "description": "A esophageal cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1107", "evidence": [ { "id": "1107", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1107" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1790", "name": "malignant mesothelioma", "description": "A cell type cancer that has_material_basis_in mesothelial tissue that develops from the thin layer of tissue that covers many of the internal organs. Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.", "url": "https://disease-ontology.org/term/DOID:1790", "evidence": [ { "id": "1790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1790" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0040036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040036", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" }, { "name": "programmed cell death", "id": "GO:0012501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012501", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" }, { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI0", "url": "https://www.uniprot.org/uniprotkb/Q6GMI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6GMI7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6GMI7", "url": "https://www.uniprot.org/uniprotkb/Q6GMI7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 261, "chemical_mass": 29978.0, "gene_names": "enoph1;enoph1;masa;zgc:91991", "protein_name": "Enolase-phosphatase E1", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI7", "url": "https://www.uniprot.org/uniprotkb/Q6GMI7" } ], "pmid": "" }, { "name": "acireductone synthase activity", "id": "GO:0043874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043874", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI7", "url": "https://www.uniprot.org/uniprotkb/Q6GMI7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI7", "url": "https://www.uniprot.org/uniprotkb/Q6GMI7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI7", "url": "https://www.uniprot.org/uniprotkb/Q6GMI7" } ], "pmid": "" } ], "biological_process": [ { "name": "L-methionine salvage from methylthioadenosine", "id": "GO:0019509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019509", "evidence": [ { "database": "UniProtKB", "id": "Q6GMI7", "url": "https://www.uniprot.org/uniprotkb/Q6GMI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6IQ73-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 224, "chemical_mass": 25176.0, "gene_names": "chmp4c;c20orf178;chmp4bb;chmp4b;wu:fc96b02;zgc:55566", "protein_name": "Charged multivesicular body protein 4c", "disease": [ { "disease_id": "DOID:0110265", "name": "cataract 31 multiple types", "description": "A cataract that has_material_basis_in heterozygous mutation in the CHMP4B gene on chromosome 20q11.", "url": "https://disease-ontology.org/term/DOID:0110265", "evidence": [ { "id": "0110265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110265" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" } ], "biological_process": [ { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "vesicle budding from membrane", "id": "GO:0006900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006900", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "negative regulation of cytokinesis", "id": "GO:0032466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032466", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "mitotic cytokinesis checkpoint signaling", "id": "GO:0044878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044878", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "Q6IQ73", "url": "https://www.uniprot.org/uniprotkb/Q6IQ73" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6IQ73-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6IQE5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 341, "chemical_mass": 38339.0, "gene_names": "get3;asna1;get3;si:dkey-121b10.2;trc40;wu:fd05d03;zgc:56540;zgc:86799", "protein_name": "ATPase GET3", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "biological_process": [ { "name": "post-translational protein targeting to endoplasmic reticulum membrane", "id": "GO:0006620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006620", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "pmid": "" }, { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "pmid": "" }, { "name": "GET complex", "id": "GO:0043529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043529", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6IQE5-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Ser4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6IQE5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6IQE5" } ] } ] }, { "uniprot_canonical_ac": "Q6IQE5-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Glu114", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "P", "comment": "No effect on interaction with GET4. No effect on tail-anchored protein delivery.", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" }, { "database": "PubMed", "id": "34887561", "url": "https://glygen.org/publication/PubMed/34887561" } ] } ] }, { "uniprot_canonical_ac": "Q6IQE5-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Asp68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "No effect on interaction with GET4. Reduces tail-anchored protein delivery.", "evidence": [ { "database": "UniProtKB", "id": "Q6IQE5", "url": "https://www.uniprot.org/uniprotkb/Q6IQE5" }, { "database": "PubMed", "id": "34887561", "url": "https://glygen.org/publication/PubMed/34887561" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6KC13-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6KC13", "url": "https://www.uniprot.org/uniprotkb/Q6KC13" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 339, "chemical_mass": 38844.0, "gene_names": "st8sia1;siat 8A;st8sia1;zgc:158304", "protein_name": "Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase", "disease": [], "molecular_function": [ { "name": "alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity", "id": "GO:0003828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003828", "evidence": [ { "database": "UniProtKB", "id": "Q6KC13", "url": "https://www.uniprot.org/uniprotkb/Q6KC13" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6KC13", "url": "https://www.uniprot.org/uniprotkb/Q6KC13" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid metabolic process", "id": "GO:0006665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006665", "evidence": [ { "database": "UniProtKB", "id": "Q6KC13", "url": "https://www.uniprot.org/uniprotkb/Q6KC13" } ], "pmid": "" }, { "name": "oligosaccharide metabolic process", "id": "GO:0009311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009311", "evidence": [ { "database": "UniProtKB", "id": "Q6KC13", "url": "https://www.uniprot.org/uniprotkb/Q6KC13" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "Q6KC13", "url": "https://www.uniprot.org/uniprotkb/Q6KC13" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NSM8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1187, "chemical_mass": 130967.0, "gene_names": "sik3;zgc:66101;zgc:85904", "protein_name": "Serine/threonine-protein kinase SIK3 homolog", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NSM8-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Thr498", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6NSM8-1", "start_pos": "942", "end_pos": "942", "site_lbl": "Thr942", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 942, "start_aa": "Thr", "end_pos": 942, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr942", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6NSM8-1", "start_pos": "975", "end_pos": "975", "site_lbl": "Thr975", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 975, "start_aa": "Thr", "end_pos": 975, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr975", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6NSM8-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Thr214", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ] } ] }, { "uniprot_canonical_ac": "Q6NSM8-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6NSM8", "url": "https://www.uniprot.org/uniprotkb/Q6NSM8" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NUT7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 814, "chemical_mass": 90980.0, "gene_names": "sort1a;sort1;sort1;zgc:85953", "protein_name": "Sortilin", "disease": [ { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "Q6NUT7", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NUT7-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Asn146", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 146, "start_aa": "Asn", "end_pos": 146, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn146", "evidence": [ { "id": "Q6NUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NUT7-1", "start_pos": "257", "end_pos": "257", "site_lbl": "Asn257", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 257, "start_aa": "Asn", "end_pos": 257, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn257", "evidence": [ { "id": "Q6NUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NUT7-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Asn388", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 388, "start_aa": "Asn", "end_pos": 388, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn388", "evidence": [ { "id": "Q6NUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NUT7-1", "start_pos": "544", "end_pos": "544", "site_lbl": "Asn544", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 544, "start_aa": "Asn", "end_pos": 544, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn544", "evidence": [ { "id": "Q6NUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NUT7-1", "start_pos": "565", "end_pos": "565", "site_lbl": "Asn565", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 565, "start_aa": "Asn", "end_pos": 565, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn565", "evidence": [ { "id": "Q6NUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NUT7-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Asn666", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 666, "start_aa": "Asn", "end_pos": 666, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn666", "evidence": [ { "id": "Q6NUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6NUT7-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Asn82", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 82, "start_aa": "Asn", "end_pos": 82, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn82", "evidence": [ { "id": "Q6NUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NUT7#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NUW5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 250, "chemical_mass": 28135.0, "gene_names": "anp32e;anp32e;wu:fb22e03;wu:fc04c12;wu:fc19a08;wu:fc79f04;wu:fi39c10;zgc:65995;zgc:85827", "protein_name": "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "disease": [ { "disease_id": "DOID:1508", "name": "candidiasis", "description": "An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.", "url": "https://disease-ontology.org/term/DOID:1508", "evidence": [ { "id": "1508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1508" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatase inhibitor activity", "id": "GO:0019212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019212", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NUW5-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6NUW5", "url": "https://www.uniprot.org/uniprotkb/Q6NUW5" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6NUW5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NUW5" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NV25-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 94, "chemical_mass": 10683.0, "gene_names": "sumo3l;fa94a11;im:7141764;sumo2;sumo3a;sumo3l;sumo3;wu:fa94a11;wu:fb55d09;zgc:65847;zgc:85643", "protein_name": "Small ubiquitin-related modifier 3-like", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "pmid": "" } ], "biological_process": [ { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "pmid": "" }, { "name": "protein tag activity", "id": "GO:0031386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031386", "evidence": [ { "database": "UniProtKB", "id": "Q6NV25", "url": "https://www.uniprot.org/uniprotkb/Q6NV25" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NVC9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 846, "chemical_mass": 96380.0, "gene_names": "jmy;jmy;zgc:77377", "protein_name": "Junction-mediating and -regulatory protein", "disease": [], "biological_process": [ { "name": "actin polymerization-dependent cell motility", "id": "GO:0070358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070358", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "'de novo' actin filament nucleation", "id": "GO:0070060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070060", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "Arp2/3 complex-mediated actin nucleation", "id": "GO:0034314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034314", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" } ], "cellular_component": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" }, { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "Q6NVC9", "url": "https://www.uniprot.org/uniprotkb/Q6NVC9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NW85-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 533, "chemical_mass": 62258.0, "gene_names": "arih1l;arih1l;wu:fc12f04;zgc:85905", "protein_name": "E3 ubiquitin-protein ligase arih1l", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q6NW85", "url": "https://www.uniprot.org/uniprotkb/Q6NW85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NW96-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 439, "chemical_mass": 46772.0, "gene_names": "sp9;sp9;zgc:85876", "protein_name": "Transcription factor Sp9", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" }, { "name": "embryonic limb morphogenesis", "id": "GO:0030326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030326", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" }, { "name": "positive regulation of fibroblast growth factor receptor signaling pathway", "id": "GO:0045743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045743", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" }, { "name": "embryonic pectoral fin morphogenesis", "id": "GO:0035118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035118", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q6NW96", "url": "https://www.uniprot.org/uniprotkb/Q6NW96" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NW96-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Thr227", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 227, "start_aa": "Thr", "end_pos": 227, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr227", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NWD4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 387, "chemical_mass": 43881.0, "gene_names": "timm50;tim50;timm50;zgc:66357", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM50", "disease": [ { "disease_id": "DOID:0070002", "name": "3-methylglutaconic aciduria type 9", "description": "A 3-methylglutaconic aciduria that has_material_basis_in homozygous mutation in the TIMM50 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0070002", "evidence": [ { "id": "0070002", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070002" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "pmid": "" }, { "name": "TIM23 mitochondrial import inner membrane translocase complex", "id": "GO:0005744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005744", "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "pmid": "" }, { "name": "protein dephosphorylation", "id": "GO:0006470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006470", "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "pmid": "" }, { "name": "mitochondrial membrane organization", "id": "GO:0007006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007006", "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "Q6NWD4", "url": "https://www.uniprot.org/uniprotkb/Q6NWD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NWF6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 520, "chemical_mass": 57760.0, "gene_names": "krt8;DreK8;cb186;krt2-8;krt8;sb:cb186;wu:fa20h05;wu:fa95h10;wu:fb96c06;zf-K8;zfk8", "protein_name": "Keratin, type II cytoskeletal 8", "disease": [ { "disease_id": "DOID:0050448", "name": "white sponge nevus", "description": "A skin disease characterized by a defect in the normal process of keratinization of the mucosa.", "url": "https://disease-ontology.org/term/DOID:0050448", "evidence": [ { "id": "0050448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050448" } ], "weight": 0.0 }, { "disease_id": "DOID:0050449", "name": "pachyonychia congenita", "description": "A syndrome that is characterized by hypertrophic nails and hyperkeratosis of the hands and feet and has_material_basis_in gene mutations that result in changes in keratin.", "url": "https://disease-ontology.org/term/DOID:0050449", "evidence": [ { "id": "0050449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050449" } ], "weight": 0.0 }, { "disease_id": "DOID:0060877", "name": "bullous congenital ichthyosiform erythroderma", "description": "An ichthyosis characterized by congenital erythema and widespread skin blistering, blisters develop into gray hyperkeratoses with a lichenified appearance, and that has_material_basis_in heterozygous mutation in the KRT2 gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0060877", "evidence": [ { "id": "0060877", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060877" } ], "weight": 0.0 }, { "disease_id": "DOID:0070550", "name": "KRT1-related nonepidermolytic palmoplantar keratoderma", "description": "A nonepidermolytic palmoplantar keratoderma that has_material_basis_in heterozygous mutation in the KRT1 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0070550", "evidence": [ { "id": "0070550", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070550" } ], "weight": 0.0 }, { "disease_id": "DOID:0070551", "name": "epidermolytic palmoplantar keratoderma 2", "description": "An epidermolytic palmoplantar keratoderma that has_material_basis_in heterozygous mutation in the KRT1 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0070551", "evidence": [ { "id": "0070551", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070551" } ], "weight": 0.0 }, { "disease_id": "DOID:0080671", "name": "Meesmann corneal dystrophy 2", "description": "A Messmann corneal dystrophy that is characterized by fragility of the anterior corneal epithelium and the presence of intraepithelial microcysts and that has_material_basis_in heterozygous mutation in the KRT3 gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0080671", "evidence": [ { "id": "0080671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080671" } ], "weight": 0.0 }, { "disease_id": "DOID:0081110", "name": "keratosis palmoplantaris striata 3", "description": "A keratosis palmoplantaris striata that has_material_basis_in heterozygous mutation in the keratin-1 gene (KRT1) on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0081110", "evidence": [ { "id": "0081110", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081110" } ], "weight": 0.0 }, { "disease_id": "DOID:0081287", "name": "white sponge nevus 1", "description": "A white sponge nevus that has_material_basis_in heterozygous mutation in the keratin-4 gene (KRT4) on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0081287", "evidence": [ { "id": "0081287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081287" } ], "weight": 0.0 }, { "disease_id": "DOID:0081358", "name": "epidermolytic hyperkeratosis 1", "description": "An epidermolytic hyperkeratosis that is characterized in adulthood by warty flexural hyperkeratosis with fewer erosions and blisters and that usually presents at birth with erythema and blistering and that has_material_basis_in heterozygous mutation in the keratin-1 gene (KRT1) on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0081358", "evidence": [ { "id": "0081358", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081358" } ], "weight": 0.0 }, { "disease_id": "DOID:0110700", "name": "hypotrichosis 3", "description": "A hypotrichosis that has_material_basis_in a autosomal dominant mutation of the KRT74 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0110700", "evidence": [ { "id": "0110700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110700" } ], "weight": 0.0 }, { "disease_id": "DOID:0110710", "name": "hypotrichosis 13", "description": "A hypotrichosis that has_material_basis_in a autosomal dominant mutation of the KRT71 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0110710", "evidence": [ { "id": "0110710", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110710" } ], "weight": 0.0 }, { "disease_id": "DOID:0111573", "name": "autosomal dominant woolly hair", "description": "A familial woolly hair syndrome that has_material_basis_in heterozygous mutation in the KRT74 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0111573", "evidence": [ { "id": "0111573", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111573" } ], "weight": 0.0 }, { "disease_id": "DOID:0111658", "name": "ectodermal dysplasia 4", "description": "A pure hair and nail ectodermal dysplasia that has_material_basis_in homozygous or compound heterozygous mutation in the KRT85 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0111658", "evidence": [ { "id": "0111658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111658" } ], "weight": 0.0 }, { "disease_id": "DOID:0111660", "name": "ectodermal dysplasia 7", "description": "A pure hair and nail ectodermal dysplasia that has_material_basis_in homozygous or compound heterozygous mutation in the KRT74 gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0111660", "evidence": [ { "id": "0111660", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111660" } ], "weight": 0.0 }, { "disease_id": "DOID:0111710", "name": "focal or diffuse nonepidermolytic palmoplantar keratoderma", "description": "A nonepidermolytic palmoplantar keratoderma characterized by focal or diffuse palmoplantar keratodermas with minor or absent nail changes that has_material_basis_in heterozygous mutation in the KRT6C gene on chromosome 12q13.13.", "url": "https://disease-ontology.org/term/DOID:0111710", "evidence": [ { "id": "0111710", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111710" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1697", "name": "ichthyosis", "description": "A skin disease characterized by drying and scaling of skin with the accumulation of thick scales and cracks that may be painful or bleed.", "url": "https://disease-ontology.org/term/DOID:1697", "evidence": [ { "id": "1697", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1697" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:4603", "name": "epidermolytic hyperkeratosis", "description": "An ichthyosis that is characterized by generalized erythema, skin blisters and skin fragility, manifested at birth.", "url": "https://disease-ontology.org/term/DOID:4603", "evidence": [ { "id": "4603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4603" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:987", "name": "alopecia", "description": "A hypotrichosis that is characterized by a loss of hair from the head or body.", "url": "https://disease-ontology.org/term/DOID:987", "evidence": [ { "id": "987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:987" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" } ], "biological_process": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NWF6-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6NWF6", "url": "https://www.uniprot.org/uniprotkb/Q6NWF6" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6NWF6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NWF6" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NWG0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWG0", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 243, "chemical_mass": 26885.0, "gene_names": "tspan36;sb:cb666;tspan36;tspan3c;zgc:100919", "protein_name": "Tetraspanin-36", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG0", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG0", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG0", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0" } ], "pmid": "" } ], "biological_process": [ { "name": "pigmentation", "id": "GO:0043473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043473", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG0", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NWG0-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Asn149", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 149, "start_aa": "Asn", "end_pos": 149, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn149", "evidence": [ { "id": "Q6NWG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q6NWG0-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Asn163", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 163, "start_aa": "Asn", "end_pos": 163, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn163", "evidence": [ { "id": "Q6NWG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q6NWG0-1", "start_pos": "174", "end_pos": "174", "site_lbl": "Asn174", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 174, "start_aa": "Asn", "end_pos": 174, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn174", "evidence": [ { "id": "Q6NWG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q6NWG0-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ile18", "weight": 0.0, "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "R", "comment": "In dali; retained in the endoplasmic reticulum. Incomplete N-glycosylation. Defective migration and cell-cell interaction between melanophores and xanthophores, leading to abnormal pigment stripe patterning.", "evidence": [ { "database": "UniProtKB", "id": "Q6NWG0", "url": "https://www.uniprot.org/uniprotkb/Q6NWG0" }, { "database": "PubMed", "id": "24734316", "url": "https://glygen.org/publication/PubMed/24734316" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NWL1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 210, "chemical_mass": 24425.0, "gene_names": "pdcd10b;pdcd10b;zgc:85629", "protein_name": "Programmed cell death protein 10-B", "disease": [ { "disease_id": "DOID:0060669", "name": "cerebral cavernous malformation", "description": "A cerebrovascular disease that is characterized by dilated blood-filled capillaries lacking structural support.", "url": "https://disease-ontology.org/term/DOID:0060669", "evidence": [ { "id": "0060669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060669" } ], "weight": 0.0 }, { "disease_id": "DOID:0060671", "name": "cerebral cavernous malformation 3", "description": "A cerebral cavernous malformation that has_material_basis_in mutation in the PDCD10 gene on chromosome 3q26.1.", "url": "https://disease-ontology.org/term/DOID:0060671", "evidence": [ { "id": "0060671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060671" } ], "weight": 0.0 }, { "disease_id": "DOID:12337", "name": "varicocele", "description": "", "url": "https://disease-ontology.org/term/DOID:12337", "evidence": [ { "id": "12337", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12337" } ], "weight": 0.0 }, { "disease_id": "DOID:2237", "name": "hepatitis", "description": "A liver disease that is characterized as an inflammation of the liver.", "url": "https://disease-ontology.org/term/DOID:2237", "evidence": [ { "id": "2237", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2237" } ], "weight": 0.0 }, { "disease_id": "DOID:2870", "name": "endometrial adenocarcinoma", "description": "An endometrial carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2870", "evidence": [ { "id": "2870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2870" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:686", "name": "liver carcinoma", "description": "A liver cancer that has_material_basis_in epithelial cells.", "url": "https://disease-ontology.org/term/DOID:686", "evidence": [ { "id": "686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:686" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "FAR/SIN/STRIPAK complex", "id": "GO:0090443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090443", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "blood vessel morphogenesis", "id": "GO:0048514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048514", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "blood vessel development", "id": "GO:0001568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001568", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "Golgi reassembly", "id": "GO:0090168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090168", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q6NWL1", "url": "https://www.uniprot.org/uniprotkb/Q6NWL1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NWX7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 223, "chemical_mass": 25265.0, "gene_names": "ntmt1;NTM1A;mettl11a;ntmt1;zgc:77488", "protein_name": "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "disease": [], "biological_process": [ { "name": "N-terminal peptidyl-glycine methylation", "id": "GO:0018013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018013", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" }, { "name": "N-terminal peptidyl-proline dimethylation", "id": "GO:0018016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018016", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" }, { "name": "N-terminal peptidyl-serine dimethylation", "id": "GO:0035572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035572", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" }, { "name": "N-terminal peptidyl-serine trimethylation", "id": "GO:0035573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035573", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" }, { "name": "spindle organization", "id": "GO:0007051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007051", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" } ], "molecular_function": [ { "name": "N-terminal protein N-methyltransferase activity", "id": "GO:0071885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071885", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" }, { "name": "protein methyltransferase activity", "id": "GO:0008276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008276", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NWX7", "url": "https://www.uniprot.org/uniprotkb/Q6NWX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NY74-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 601, "chemical_mass": 66631.0, "gene_names": "rpa1;rpa1;wu:fi14b08;zgc:55337;zgc:77092", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "DNA replication factor A complex", "id": "GO:0005662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005662", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "protein localization to chromosome", "id": "GO:0034502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034502", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "telomere maintenance via telomerase", "id": "GO:0007004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007004", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" }, { "name": "single-stranded telomeric DNA binding", "id": "GO:0043047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043047", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NY74-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6NY74", "url": "https://www.uniprot.org/uniprotkb/Q6NY74" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6NY74", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NY74" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NY98-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 598, "chemical_mass": 68144.0, "gene_names": "rngtt;rngtt;si:ch211-241P10.5;zgc:76886", "protein_name": "mRNA-capping enzyme", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "pmid": "" }, { "name": "mRNA guanylyltransferase activity", "id": "GO:0004484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004484", "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "pmid": "" }, { "name": "inorganic triphosphate phosphatase activity", "id": "GO:0050355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050355", "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "pmid": "" }, { "name": "mRNA 5'-triphosphate monophosphatase activity", "id": "GO:0140818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140818", "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "pmid": "" } ], "biological_process": [ { "name": "7-methylguanosine mRNA capping", "id": "GO:0006370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006370", "evidence": [ { "database": "UniProtKB", "id": "Q6NY98", "url": "https://www.uniprot.org/uniprotkb/Q6NY98" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NY98-1", "start_pos": "99", "end_pos": "99", "site_lbl": "Thr99", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 99, "start_aa": "Thr", "end_pos": 99, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr99", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYE2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 495, "chemical_mass": 54152.0, "gene_names": "rcc2;rcc2;td-60;wu:fb36a03;zgc:77115", "protein_name": "Protein RCC2 homolog", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" }, { "name": "chromosome passenger complex localization to kinetochore", "id": "GO:0072356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072356", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" }, { "name": "positive regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051987", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q6NYE2", "url": "https://www.uniprot.org/uniprotkb/Q6NYE2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYG8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1022, "chemical_mass": 111004.0, "gene_names": "dpyd;dpydb;dpyd;zgc:77205", "protein_name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "disease": [ { "disease_id": "DOID:14218", "name": "dihydropyrimidine dehydrogenase deficiency", "description": "A purine-pyrimidine metabolic disorder that is an autosomal recessive metabolic disorder in which there is absent or significantly decreased activity of dihydropyrimidine dehydrogenase, an enzyme involved in the metabolism of uracil and thymine.", "url": "https://disease-ontology.org/term/DOID:14218", "evidence": [ { "id": "14218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14218" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:3121", "name": "gallbladder cancer", "description": "A biliary tract cancer that is located_in the gallbladder.", "url": "https://disease-ontology.org/term/DOID:3121", "evidence": [ { "id": "3121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3121" } ], "weight": 0.0 }, { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "uracil binding", "id": "GO:0002058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002058", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" }, { "name": "dihydropyrimidine dehydrogenase (NADP+) activity", "id": "GO:0017113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017113", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" } ], "biological_process": [ { "name": "thymine catabolic process", "id": "GO:0006210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006210", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" }, { "name": "uracil catabolic process", "id": "GO:0006212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006212", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" }, { "name": "thymidine catabolic process", "id": "GO:0006214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006214", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" }, { "name": "beta-alanine biosynthetic process", "id": "GO:0019483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019483", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6NYG8", "url": "https://www.uniprot.org/uniprotkb/Q6NYG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYK8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 289, "chemical_mass": 32106.0, "gene_names": "marchf5;march5l;march5;marchf5l;marchf5;wu:fd60f03;zgc:162966;zgc:56713", "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "disease": [], "biological_process": [ { "name": "regulation of mitochondrial fission", "id": "GO:0090140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090140", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6NYK8", "url": "https://www.uniprot.org/uniprotkb/Q6NYK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYU3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 327, "chemical_mass": 36949.0, "gene_names": "neurod6a;Zath2a;atoh2a;ndr1a;neuroD6-A;neurod6a", "protein_name": "Neurogenic differentiation factor 6-A", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" }, { "name": "positive regulation of neurogenesis", "id": "GO:0050769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050769", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "Q6NYU3", "url": "https://www.uniprot.org/uniprotkb/Q6NYU3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NYU3-1", "start_pos": "213", "end_pos": "213", "site_lbl": "Thr213", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NYX6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 764, "chemical_mass": 84906.0, "gene_names": "ccnf;cb443;ccnf;zgc:77240", "protein_name": "Cyclin-F", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "negative regulation of centrosome duplication", "id": "GO:0010826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010826", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" } ], "molecular_function": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "Q6NYX6", "url": "https://www.uniprot.org/uniprotkb/Q6NYX6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6NZZ9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 425, "chemical_mass": 47440.0, "gene_names": "rbm22;fb37a01;fc62e03;fe05c04;rbm22;wu:fb37a01;wu:fc62e03;wu:fe05c04;zgc:77910", "protein_name": "Pre-mRNA-splicing factor RBM22", "disease": [], "molecular_function": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" }, { "name": "U6 snRNA binding", "id": "GO:0017070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of RNA splicing", "id": "GO:0033120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033120", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" }, { "name": "Prp19 complex", "id": "GO:0000974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", "evidence": [ { "database": "UniProtKB", "id": "Q6NZZ9", "url": "https://www.uniprot.org/uniprotkb/Q6NZZ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6NZZ9-1", "start_pos": "354", "end_pos": "354", "site_lbl": "Thr354", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 354, "start_aa": "Thr", "end_pos": 354, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr354", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P026-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 90, "chemical_mass": 10228.0, "gene_names": "banf1;baf;banf1;fa01c01;wu:fa01c01;zgc:77767", "protein_name": "Barrier-to-autointegration factor", "disease": [ { "disease_id": "DOID:0081334", "name": "Nestor-Guillermo progeria syndrome", "description": "A progeroid syndrome that is characterized by lipoatrophy, osteoporosis, and very severe osteolysis. Patients have no cardiovascular impairment, diabetes mellitus, or hypertriglyceridemia, but suffer profound skeletal abnormalities that affect their quality of life and that has_material_basis_in homozygous mutation in the BANF1 gene on chromosome 11q13. Onset is after 2 years of age.", "url": "https://disease-ontology.org/term/DOID:0081334", "evidence": [ { "id": "0081334", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081334" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "condensed chromosome", "id": "GO:0000793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000793", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "mitotic nuclear membrane reassembly", "id": "GO:0007084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007084", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "negative regulation of protein ADP-ribosylation", "id": "GO:0010836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010836", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" }, { "name": "negative regulation of type I interferon production", "id": "GO:0032480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032480", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P026-1", "start_pos": "2", "end_pos": "2", "site_lbl": "Ser2", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6P026", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P026" } ] } ] }, { "uniprot_canonical_ac": "Q6P026-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Ser3", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6P026", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P026" } ] } ] }, { "uniprot_canonical_ac": "Q6P026-1", "start_pos": "4", "end_pos": "4", "site_lbl": "Thr4", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6P026", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P026" } ] } ] }, { "uniprot_canonical_ac": "Q6P026-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Ser5", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6P026", "url": "https://www.uniprot.org/uniprotkb/Q6P026" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6P026", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P026" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P0B1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0B1", "url": "https://www.uniprot.org/uniprotkb/Q6P0B1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 514, "chemical_mass": 54552.0, "gene_names": "celf2;Etr-3;cb906;celf2;cugbp2;etr3;fj87b07;wu:fj87b07", "protein_name": "CUGBP Elav-like family member 2", "disease": [ { "disease_id": "DOID:0070383", "name": "developmental and epileptic encephalopathy 97", "description": "A developmental and epileptic encephalopathy characterized by onset of seizures in the first months of life that has_material_basis_in heterozygous mutation in the CELF2 gene on chromosome 10p14.", "url": "https://disease-ontology.org/term/DOID:0070383", "evidence": [ { "id": "0070383", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070383" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P0B1", "url": "https://www.uniprot.org/uniprotkb/Q6P0B1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P0B1", "url": "https://www.uniprot.org/uniprotkb/Q6P0B1" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q6P0B1", "url": "https://www.uniprot.org/uniprotkb/Q6P0B1" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "Q6P0B1", "url": "https://www.uniprot.org/uniprotkb/Q6P0B1" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "Q6P0B1", "url": "https://www.uniprot.org/uniprotkb/Q6P0B1" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q6P0B1", "url": "https://www.uniprot.org/uniprotkb/Q6P0B1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P0F4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0F4", "url": "https://www.uniprot.org/uniprotkb/Q6P0F4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 252, "chemical_mass": 28710.0, "gene_names": "rbm7;zgc:77304", "protein_name": "RNA-binding protein 7", "disease": [], "biological_process": [ { "name": "cerebellar Purkinje cell layer structural organization", "id": "GO:0021693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021693", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F4", "url": "https://www.uniprot.org/uniprotkb/Q6P0F4" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F4", "url": "https://www.uniprot.org/uniprotkb/Q6P0F4" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F4", "url": "https://www.uniprot.org/uniprotkb/Q6P0F4" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F4", "url": "https://www.uniprot.org/uniprotkb/Q6P0F4" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F4", "url": "https://www.uniprot.org/uniprotkb/Q6P0F4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F4", "url": "https://www.uniprot.org/uniprotkb/Q6P0F4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6P0F4", "url": "https://www.uniprot.org/uniprotkb/Q6P0F4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P0T2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P0T2", "url": "https://www.uniprot.org/uniprotkb/Q6P0T2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 308, "chemical_mass": 33912.0, "gene_names": "taf8;taf8;tbnl;zgc:56401;zgc:77837", "protein_name": "Transcription initiation factor TFIID subunit 8", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P0T2", "url": "https://www.uniprot.org/uniprotkb/Q6P0T2" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "Q6P0T2", "url": "https://www.uniprot.org/uniprotkb/Q6P0T2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q6P0T2", "url": "https://www.uniprot.org/uniprotkb/Q6P0T2" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "Q6P0T2", "url": "https://www.uniprot.org/uniprotkb/Q6P0T2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q6P0T2", "url": "https://www.uniprot.org/uniprotkb/Q6P0T2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P0T2-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6P0T2", "url": "https://www.uniprot.org/uniprotkb/Q6P0T2" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6P0T2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6P0T2" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P268-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 239, "chemical_mass": 27657.0, "gene_names": "pdcl3;pdcl3;viaf1;zgc:73170", "protein_name": "Phosducin-like protein 3", "disease": [], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" } ], "molecular_function": [ { "name": "vascular endothelial growth factor receptor 2 binding", "id": "GO:0043184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043184", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6P268-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6P268", "url": "https://www.uniprot.org/uniprotkb/Q6P268" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P271-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1023, "chemical_mass": 112523.0, "gene_names": "atp1a3a;atp1a3a;atp[a]3B;cb705;wu:fj56a06", "protein_name": "Sodium/potassium-transporting ATPase subunit alpha", "disease": [ { "disease_id": "DOID:0050635", "name": "alternating hemiplegia of childhood", "description": "A hemiplegia characterized by recurrent episodes of temporary weakness or complete paralysis on one or both sides of the body.", "url": "https://disease-ontology.org/term/DOID:0050635", "evidence": [ { "id": "0050635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050635" } ], "weight": 0.0 }, { "disease_id": "DOID:0060178", "name": "familial hemiplegic migraine", "description": "A migraine with aura that is characterized by temporary numbness or weakness, often affecting one side of the body (hemiparesis). Additional features of an aura can include difficulty with speech, confusion, and drowsiness.", "url": "https://disease-ontology.org/term/DOID:0060178", "evidence": [ { "id": "0060178", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060178" } ], "weight": 0.0 }, { "disease_id": "DOID:0070385", "name": "developmental and epileptic encephalopathy 99", "description": "A developmental and epileptic encephalopathy characterized by onset of seizures in early childhood that has_material_basis_in heterozygous mutation in the ATP1A3 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0070385", "evidence": [ { "id": "0070385", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070385" } ], "weight": 0.0 }, { "disease_id": "DOID:0090056", "name": "dystonia 12", "description": "A dystonia that is characterized by asymmetric dystonia and parkinsonism with abrupt onset in young adulthood that has_material_basis_in autosomal dominant inheritance of heterozygous mutation in the gene encoding the alpha-3 subunit of the N,K-ATPase (ATP1A3) on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0090056", "evidence": [ { "id": "0090056", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090056" } ], "weight": 0.0 }, { "disease_id": "DOID:0111558", "name": "Charcot-Marie-Tooth disease type 2DD", "description": "A Charcot-Marie-Tooth disease type 2 characterized by neuropathy mainly affecting the lower limbs that has_material_basis_in heterozygous mutation in the ATP1A1 gene on chromosome 1p13.1.", "url": "https://disease-ontology.org/term/DOID:0111558", "evidence": [ { "id": "0111558", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111558" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:863", "name": "nervous system disease", "description": "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.", "url": "https://disease-ontology.org/term/DOID:863", "evidence": [ { "id": "863", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:863" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "P-type sodium:potassium-exchanging transporter activity", "id": "GO:0005391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005391", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" } ], "biological_process": [ { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "intracellular sodium ion homeostasis", "id": "GO:0006883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006883", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "ventricular system development", "id": "GO:0021591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021591", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "intracellular potassium ion homeostasis", "id": "GO:0030007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030007", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "sodium ion export across plasma membrane", "id": "GO:0036376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036376", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "Q6P271", "url": "https://www.uniprot.org/uniprotkb/Q6P271" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P3J5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 858, "chemical_mass": 95498.0, "gene_names": "eef2b;EEF2;eef2b;eef2l;fe49h02;wu:fe49h02;zgc:63584", "protein_name": "Elongation factor 2b", "disease": [ { "disease_id": "DOID:0050975", "name": "spinocerebellar ataxia 26", "description": "An autosomal dominant cerebellar ataxia that is characterized by slowly progressive ataxia and oculomotor abnormalities, has_material_basis_in mutation in the EEF2 gene.", "url": "https://disease-ontology.org/term/DOID:0050975", "evidence": [ { "id": "0050975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050975" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1686", "name": "glaucoma", "description": "An eye disease that is characterized by an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function.", "url": "https://disease-ontology.org/term/DOID:1686", "evidence": [ { "id": "1686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1686" } ], "weight": 0.0 }, { "disease_id": "DOID:1996", "name": "rectum adenocarcinoma", "description": "A rectum cancer that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:1996", "evidence": [ { "id": "1996", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1996" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:3073", "name": "brain glioblastoma multiforme", "description": "A brain glioma that has_material_basis_in abnormally proliferating cells derives_from glial cells, has_symptom seizure, headaches, nausea and vomiting, memory loss, changes to personality, mood or concentration; and localized neurological problems.", "url": "https://disease-ontology.org/term/DOID:3073", "evidence": [ { "id": "3073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3073" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" }, { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q6P3J5", "url": "https://www.uniprot.org/uniprotkb/Q6P3J5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P3L6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P3L6", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 319, "chemical_mass": 35551.0, "gene_names": "hsd17b12a;KAR;fi06g11;hsd17b12a;wu:fi06g11;zgc:55589;zgc:77599", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase-A", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6P3L6", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6P3L6", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q6P3L6", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ], "pmid": "" }, { "name": "estrogen biosynthetic process", "id": "GO:0006703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006703", "evidence": [ { "database": "UniProtKB", "id": "Q6P3L6", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q6P3L6", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ], "pmid": "" }, { "name": "estradiol 17-beta-dehydrogenase [NAD(P)+] activity", "id": "GO:0004303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004303", "evidence": [ { "database": "UniProtKB", "id": "Q6P3L6", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ], "pmid": "" }, { "name": "very-long-chain 3-oxoacyl-CoA reductase activity", "id": "GO:0141040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141040", "evidence": [ { "database": "UniProtKB", "id": "Q6P3L6", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P4U6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 215, "chemical_mass": 22875.0, "gene_names": "znrf1;zgc:77896;znrf1", "protein_name": "E3 ubiquitin-protein ligase znrf1", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "Q6P4U6", "url": "https://www.uniprot.org/uniprotkb/Q6P4U6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6P963-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6P963", "url": "https://www.uniprot.org/uniprotkb/Q6P963" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 303, "chemical_mass": 33806.0, "gene_names": "hagh;fa66a03;hagh;wu:fa66a03;zgc:73161", "protein_name": "Hydroxyacylglutathione hydrolase, mitochondrial", "disease": [], "molecular_function": [ { "name": "hydroxyacylglutathione hydrolase activity", "id": "GO:0004416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004416", "evidence": [ { "database": "UniProtKB", "id": "Q6P963", "url": "https://www.uniprot.org/uniprotkb/Q6P963" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6P963", "url": "https://www.uniprot.org/uniprotkb/Q6P963" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q6P963", "url": "https://www.uniprot.org/uniprotkb/Q6P963" } ], "pmid": "" } ], "biological_process": [ { "name": "methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "id": "GO:0019243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019243", "evidence": [ { "database": "UniProtKB", "id": "Q6P963", "url": "https://www.uniprot.org/uniprotkb/Q6P963" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "Q6P963", "url": "https://www.uniprot.org/uniprotkb/Q6P963" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6P963", "url": "https://www.uniprot.org/uniprotkb/Q6P963" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q6P963", "url": "https://www.uniprot.org/uniprotkb/Q6P963" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PBI4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 582, "chemical_mass": 65117.0, "gene_names": "hdac9b;hdac9;zgc:73392", "protein_name": "Histone deacetylase 9-B", "disease": [ { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 } ], "biological_process": [ { "name": "primitive erythrocyte differentiation", "id": "GO:0060319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060319", "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "pmid": "" }, { "name": "primitive hemopoiesis", "id": "GO:0060215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060215", "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "pmid": "" }, { "name": "lymph vessel development", "id": "GO:0001945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001945", "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone deacetylase activity, hydrolytic mechanism", "id": "GO:0141221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141221", "evidence": [ { "database": "UniProtKB", "id": "Q6PBI4", "url": "https://www.uniprot.org/uniprotkb/Q6PBI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PBM1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PBM1", "url": "https://www.uniprot.org/uniprotkb/Q6PBM1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 155, "chemical_mass": 17377.0, "gene_names": "glrx5;glrx5;grx5;id:ibd5119;shiraz;si:ch211-121d13.1;wu:fa09g08;zgc:73343", "protein_name": "Glutaredoxin-related protein 5, mitochondrial", "disease": [ { "disease_id": "DOID:0080343", "name": "autosomal recessive pyridoxine-refractory sideroblastic anemia 3", "description": "A sideroblastic anemia that is characterized by homozygous or compound heterozygous mutation in the GLRX5 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0080343", "evidence": [ { "id": "0080343", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080343" } ], "weight": 0.0 } ], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "Q6PBM1", "url": "https://www.uniprot.org/uniprotkb/Q6PBM1" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "Q6PBM1", "url": "https://www.uniprot.org/uniprotkb/Q6PBM1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PBM1", "url": "https://www.uniprot.org/uniprotkb/Q6PBM1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6PBM1", "url": "https://www.uniprot.org/uniprotkb/Q6PBM1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q6PBM1", "url": "https://www.uniprot.org/uniprotkb/Q6PBM1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6PBM1", "url": "https://www.uniprot.org/uniprotkb/Q6PBM1" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q6PBM1", "url": "https://www.uniprot.org/uniprotkb/Q6PBM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PBN2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 303, "chemical_mass": 34560.0, "gene_names": "aida;aida;zgc:73327", "protein_name": "Axin interactor, dorsalization-associated protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "pmid": "" }, { "name": "negative regulation of JUN kinase activity", "id": "GO:0043508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043508", "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "pmid": "" }, { "name": "determination of ventral identity", "id": "GO:0048264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048264", "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "pmid": "" }, { "name": "negative regulation of determination of dorsal identity", "id": "GO:2000016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000016", "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "Q6PBN2", "url": "https://www.uniprot.org/uniprotkb/Q6PBN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6PBN2-1", "start_pos": "142", "end_pos": "142", "site_lbl": "Thr142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PBX5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 181, "chemical_mass": 21423.0, "gene_names": "adi1;ARD';Fe-ARD;MTCBP-1;Ni-ARD;adi1;fc18b03;mtcbp1;wu:fc18b03;zgc:73201", "protein_name": "Acireductone dioxygenase", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" }, { "name": "nickel cation binding", "id": "GO:0016151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016151", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" }, { "name": "acireductone dioxygenase [iron(II)-requiring] activity", "id": "GO:0010309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010309", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" }, { "name": "acireductone dioxygenase (Ni2+-requiring) activity", "id": "GO:0010308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010308", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" } ], "biological_process": [ { "name": "L-methionine salvage from methylthioadenosine", "id": "GO:0019509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019509", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" }, { "name": "methionine metabolic process", "id": "GO:0006555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006555", "evidence": [ { "database": "UniProtKB", "id": "Q6PBX5", "url": "https://www.uniprot.org/uniprotkb/Q6PBX5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PC30-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 334, "chemical_mass": 37582.0, "gene_names": "cops5;cops5;jab1;zgc:73130", "protein_name": "COP9 signalosome complex subunit 5", "disease": [ { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "deNEDDylase activity", "id": "GO:0019784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019784", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" } ], "biological_process": [ { "name": "vestibular receptor cell development", "id": "GO:0060118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060118", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "Q6PC30", "url": "https://www.uniprot.org/uniprotkb/Q6PC30" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PC54-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 203, "chemical_mass": 22693.0, "gene_names": "snap25b;Snap;snap25.2;snap25b;wu:fj33h05", "protein_name": "Synaptosomal-associated protein 25-B", "disease": [ { "disease_id": "DOID:0110683", "name": "developmental and epileptic encephalopathy 117", "description": "A developmental and epileptic encephalopathy that is characterized by global developmental delay, hypotonia, delayed walking or inability to walk, and variably impaired intellectual development with poor or absent speech and that has_material_basis_in heterozygous mutation in the SNAP25 gene on chromosome 20p11.", "url": "https://disease-ontology.org/term/DOID:0110683", "evidence": [ { "id": "0110683", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110683" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex", "id": "GO:0070032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070032", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" } ], "biological_process": [ { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "clustering of voltage-gated sodium channels", "id": "GO:0045162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045162", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031629", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "syntaxin-1 binding", "id": "GO:0017075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017075", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "Q6PC54", "url": "https://www.uniprot.org/uniprotkb/Q6PC54" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PC55-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 228, "chemical_mass": 26761.0, "gene_names": "gid8a;Twa1;gid8a;gid8;twa1;zgc:73100", "protein_name": "Glucose-induced degradation protein 8-A homolog", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "pmid": "" }, { "name": "determination of dorsal identity", "id": "GO:0048263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048263", "evidence": [ { "database": "UniProtKB", "id": "Q6PC55", "url": "https://www.uniprot.org/uniprotkb/Q6PC55" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PC60-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 126, "chemical_mass": 13948.0, "gene_names": "hist2h2l;fj05g08;hist2h2l;wu:fj05g08;zgc:73093", "protein_name": "Histone H2B 3", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" } ], "biological_process": [ { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" }, { "name": "antimicrobial humoral immune response mediated by antimicrobial peptide", "id": "GO:0061844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061844", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" }, { "name": "innate immune response in mucosa", "id": "GO:0002227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002227", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6PC60-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Ser113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_pos": 113, "start_aa": "Ser", "end_pos": 113, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser113", "evidence": [ { "id": "Q6PC60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6PC60#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q6PC60-1", "start_pos": "15", "end_pos": "15", "site_lbl": "Ser15", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6PC60", "url": "https://www.uniprot.org/uniprotkb/Q6PC60" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PC78-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 194, "chemical_mass": 20520.0, "gene_names": "rnf185;rnf185;zgc:73070", "protein_name": "E3 ubiquitin-protein ligase RNF185", "disease": [], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "ubiquitin-like protein conjugating enzyme binding", "id": "GO:0044390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044390", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "positive regulation of type I interferon-mediated signaling pathway", "id": "GO:0060340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060340", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" }, { "name": "protein K27-linked ubiquitination", "id": "GO:0044314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044314", "evidence": [ { "database": "UniProtKB", "id": "Q6PC78", "url": "https://www.uniprot.org/uniprotkb/Q6PC78" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PC93-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 304, "chemical_mass": 34209.0, "gene_names": "nmnat2;nmnat2;si:dkey-161l11.3;wu:fj59g01;zgc:73048", "protein_name": "Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2", "disease": [ { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" }, { "name": "nicotinate-nucleotide adenylyltransferase activity", "id": "GO:0004515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004515", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" }, { "name": "nicotinamide-nucleotide adenylyltransferase activity", "id": "GO:0000309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000309", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" }, { "name": "protein ADP-ribosyltransferase-substrate adaptor activity", "id": "GO:0140768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140768", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" } ], "biological_process": [ { "name": "NAD+ biosynthetic process via the salvage pathway", "id": "GO:0034355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034355", "evidence": [ { "database": "UniProtKB", "id": "Q6PC93", "url": "https://www.uniprot.org/uniprotkb/Q6PC93" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PFJ9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 527, "chemical_mass": 61654.0, "gene_names": "arih1;ARI-1;arih1;si:dkey-151p17.4;si:dkey-73n10.2;wu:fa18d01;zgc:66364", "protein_name": "E3 ubiquitin-protein ligase arih1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" }, { "name": "Lewy body", "id": "GO:0097413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097413", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q6PFJ9", "url": "https://www.uniprot.org/uniprotkb/Q6PFJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PFK1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 953, "chemical_mass": 106912.0, "gene_names": "znf598;Zfp598;fc88f12;wu:fc88f12;zfp598;znf598", "protein_name": "E3 ubiquitin-protein ligase ZNF598", "disease": [], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6PFK1-1", "start_pos": "477", "end_pos": "477", "site_lbl": "Thr477", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "Q6PFK1-1", "start_pos": "489", "end_pos": "489", "site_lbl": "Ser489", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q6PFK1", "url": "https://www.uniprot.org/uniprotkb/Q6PFK1" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "Q6PFK1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6PFK1" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PFP3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PFP3", "url": "https://www.uniprot.org/uniprotkb/Q6PFP3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 117, "chemical_mass": 12645.0, "gene_names": "ppdpfa;c20orf149a;c20orf149;cb1048;exdpfa;exdpf;fb65a03;id:ibd5154;ppdpfa;wu:fb65a03;zgc:66181", "protein_name": "Pancreatic progenitor cell differentiation and proliferation factor A", "disease": [ { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP3", "url": "https://www.uniprot.org/uniprotkb/Q6PFP3" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP3", "url": "https://www.uniprot.org/uniprotkb/Q6PFP3" } ], "pmid": "" }, { "name": "exocrine pancreas development", "id": "GO:0031017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031017", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP3", "url": "https://www.uniprot.org/uniprotkb/Q6PFP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PFP6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 595, "chemical_mass": 66890.0, "gene_names": "ndor1;NDOR1;ndor1;wu:fc41f01;zgc:66159", "protein_name": "NADPH-dependent diflavin oxidoreductase 1", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" } ], "molecular_function": [ { "name": "electron transfer activity", "id": "GO:0009055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009055", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor", "id": "GO:0016653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016653", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "NADPH-iron-sulfur [2Fe-2S] protein oxidoreductase activity", "id": "GO:0160246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160246", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H", "id": "GO:0016651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016651", "evidence": [ { "database": "UniProtKB", "id": "Q6PFP6", "url": "https://www.uniprot.org/uniprotkb/Q6PFP6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PFQ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 740, "chemical_mass": 83397.0, "gene_names": "rps6ka6;rps6ka6;rps6kal;wu:fj94b02;zgc:66139", "protein_name": "Ribosomal protein S6 kinase alpha-6", "disease": [ { "disease_id": "DOID:3783", "name": "Coffin-Lowry syndrome", "description": "A syndrome that is characterized by skeletal malformations, growth retardation, hearing deficit, paroxysmal movement disorders, and cognitive impairment in affected males and some carrier females, and has_material_basis_in mutation in the RSK2 gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:3783", "evidence": [ { "id": "3783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3783" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ribosomal protein S6 kinase activity", "id": "GO:0004711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004711", "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "pmid": "" }, { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "pmid": "" } ], "biological_process": [ { "name": "TORC1 signaling", "id": "GO:0038202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038202", "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "Q6PFQ0", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PFS7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 317, "chemical_mass": 35699.0, "gene_names": "atg3;apg3l;atg3;im:6910145;wu:fb15g12;zgc:64156", "protein_name": "Ubiquitin-like-conjugating enzyme ATG3", "disease": [], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "mitochondrial fragmentation involved in apoptotic process", "id": "GO:0043653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043653", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" } ], "molecular_function": [ { "name": "Atg8-family ligase activity", "id": "GO:0019776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019776", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "Atg12 transferase activity", "id": "GO:0019777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019777", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" }, { "name": "Atg8-family conjugating enzyme activity", "id": "GO:0141046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141046", "evidence": [ { "database": "UniProtKB", "id": "Q6PFS7", "url": "https://www.uniprot.org/uniprotkb/Q6PFS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PG34-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 547, "chemical_mass": 61938.0, "gene_names": "cdkal1;cdkal1;zgc:65864", "protein_name": "Threonylcarbamoyladenosine tRNA methylthiotransferase", "disease": [ { "disease_id": "DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy.", "url": "https://disease-ontology.org/term/DOID:11714", "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "pancreas regeneration", "id": "GO:1990798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990798", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" }, { "name": "type B pancreatic cell development", "id": "GO:0003323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003323", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" }, { "name": "tRNA methylthiolation", "id": "GO:0035600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035600", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" }, { "name": "tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity", "id": "GO:0035598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035598", "evidence": [ { "database": "UniProtKB", "id": "Q6PG34", "url": "https://www.uniprot.org/uniprotkb/Q6PG34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6PG34-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Thr395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PH18-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 389, "chemical_mass": 43835.0, "gene_names": "nr2f1b;nr2f1b;nr2f1l;zgc:65854;zgc:77353", "protein_name": "Nuclear receptor subfamily 2 group F member 1-B", "disease": [ { "disease_id": "DOID:0112226", "name": "Bosch-Boonstra-Schaaf optic atrophy syndrome", "description": "A syndrome characterized by delayed development, moderate intellectual disability, and optic atrophy that has_material_basis_in heterozygous mutation in the NR2F1 gene on chromosome 5q15.", "url": "https://disease-ontology.org/term/DOID:0112226", "evidence": [ { "id": "0112226", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112226" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "venous blood vessel development", "id": "GO:0060841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060841", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "brain segmentation", "id": "GO:0035284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035284", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "angioblast cell migration", "id": "GO:0035476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035476", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "Q6PH18", "url": "https://www.uniprot.org/uniprotkb/Q6PH18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PH37-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PH37", "url": "https://www.uniprot.org/uniprotkb/Q6PH37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 299, "chemical_mass": 35035.0, "gene_names": "sult1st1", "protein_name": "Cytosolic sulfotransferase 1", "disease": [ { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "Q6PH37", "url": "https://www.uniprot.org/uniprotkb/Q6PH37" } ], "pmid": "" }, { "name": "aryl sulfotransferase activity", "id": "GO:0004062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004062", "evidence": [ { "database": "UniProtKB", "id": "Q6PH37", "url": "https://www.uniprot.org/uniprotkb/Q6PH37" } ], "pmid": "" } ], "biological_process": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "Q6PH37", "url": "https://www.uniprot.org/uniprotkb/Q6PH37" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "Q6PH37", "url": "https://www.uniprot.org/uniprotkb/Q6PH37" } ], "pmid": "" }, { "name": "catecholamine metabolic process", "id": "GO:0006584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006584", "evidence": [ { "database": "UniProtKB", "id": "Q6PH37", "url": "https://www.uniprot.org/uniprotkb/Q6PH37" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PH37", "url": "https://www.uniprot.org/uniprotkb/Q6PH37" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PHF0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PHF0", "url": "https://www.uniprot.org/uniprotkb/Q6PHF0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 198, "chemical_mass": 21888.0, "gene_names": "chmp1a;KM0004;chmp1a;km0004;pcoln3;wu:fb50a12;zgc:65914;zgc:85863", "protein_name": "Charged multivesicular body protein 1a", "disease": [ { "disease_id": "DOID:0060277", "name": "pontocerebellar hypoplasia type 8", "description": "A pontocerebellar hypoplasia that is characterized by delayed psychomotor development, chorea, hypotonia, spasticity and visual defects, has_material_basis_in autosomal recessive inheritance of mutation in the CHMP1A gene.", "url": "https://disease-ontology.org/term/DOID:0060277", "evidence": [ { "id": "0060277", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060277" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "Q6PHF0", "url": "https://www.uniprot.org/uniprotkb/Q6PHF0" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "Q6PHF0", "url": "https://www.uniprot.org/uniprotkb/Q6PHF0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6PHF0", "url": "https://www.uniprot.org/uniprotkb/Q6PHF0" } ], "pmid": "" }, { "name": "cerebellum development", "id": "GO:0021549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021549", "evidence": [ { "database": "UniProtKB", "id": "Q6PHF0", "url": "https://www.uniprot.org/uniprotkb/Q6PHF0" } ], "pmid": "" }, { "name": "late endosome to vacuole transport", "id": "GO:0045324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045324", "evidence": [ { "database": "UniProtKB", "id": "Q6PHF0", "url": "https://www.uniprot.org/uniprotkb/Q6PHF0" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "Q6PHF0", "url": "https://www.uniprot.org/uniprotkb/Q6PHF0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PHI9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 213, "chemical_mass": 24002.0, "gene_names": "rab4a;fc93b03;rab4a;wu:fc93b03", "protein_name": "Ras-related protein Rab-4A", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "regulation of endocytosis", "id": "GO:0030100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030100", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" } ], "cellular_component": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" }, { "name": "insulin-responsive compartment", "id": "GO:0032593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032593", "evidence": [ { "database": "UniProtKB", "id": "Q6PHI9", "url": "https://www.uniprot.org/uniprotkb/Q6PHI9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6PUR7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 985, "chemical_mass": 110604.0, "gene_names": "smcr8b;smcr8b;smcr8", "protein_name": "Guanine nucleotide exchange protein smcr8b", "disease": [], "biological_process": [ { "name": "negative regulation of autophagosome assembly", "id": "GO:1902902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902902", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "positive regulation of autophagosome maturation", "id": "GO:1901098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901098", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "negative regulation of macroautophagy", "id": "GO:0016242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016242", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "regulation of TORC1 signaling", "id": "GO:1903432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903432", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor complex", "id": "GO:0032045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032045", "evidence": [ { "database": "UniProtKB", "id": "Q6PUR7", "url": "https://www.uniprot.org/uniprotkb/Q6PUR7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6Q420-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 130, "chemical_mass": 14840.0, "gene_names": "rps15a;rps15a;wu:fb04b07", "protein_name": "Small ribosomal subunit protein uS8", "disease": [ { "disease_id": "DOID:0060036", "name": "intrinsic cardiomyopathy", "description": "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause.", "url": "https://disease-ontology.org/term/DOID:0060036", "evidence": [ { "id": "0060036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060036" } ], "weight": 0.0 }, { "disease_id": "DOID:0111891", "name": "Diamond-Blackfan anemia 20", "description": "A Diamond-Blackfan anemia that has_material_basis_in heterozygous mutation in the RPS15A gene on chromosome 16p12.3.", "url": "https://disease-ontology.org/term/DOID:0111891", "evidence": [ { "id": "0111891", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111891" } ], "weight": 0.0 } ], "biological_process": [ { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" } ], "cellular_component": [ { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "Q6Q420", "url": "https://www.uniprot.org/uniprotkb/Q6Q420" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6QA33-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6QA33", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 311, "chemical_mass": 34279.0, "gene_names": "hsd17b12b;KAR;fb68b12;hsd17b12b;wu:fb68b12;zgc:73289", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase-B", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q6QA33", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q6QA33", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q6QA33", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ], "pmid": "" }, { "name": "estrogen biosynthetic process", "id": "GO:0006703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006703", "evidence": [ { "database": "UniProtKB", "id": "Q6QA33", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q6QA33", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ], "pmid": "" }, { "name": "estradiol 17-beta-dehydrogenase [NAD(P)+] activity", "id": "GO:0004303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004303", "evidence": [ { "database": "UniProtKB", "id": "Q6QA33", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ], "pmid": "" }, { "name": "very-long-chain 3-oxoacyl-CoA reductase activity", "id": "GO:0141040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141040", "evidence": [ { "database": "UniProtKB", "id": "Q6QA33", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6TGU2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 364, "chemical_mass": 39817.0, "gene_names": "seh1l;fa02g03;sec13l;seh1l;si:dkey-263o22.4;wu:fa02g03;zgc:55977", "protein_name": "Nucleoporin SEH1", "disease": [], "biological_process": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "cellular response to nutrient levels", "id": "GO:0031669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031669", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "GATOR2 complex", "id": "GO:0061700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061700", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" }, { "name": "Seh1-associated complex", "id": "GO:0035859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035859", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "Q6TGU2", "url": "https://www.uniprot.org/uniprotkb/Q6TGU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6TNU4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 380, "chemical_mass": 42536.0, "gene_names": "fen1;FEN-1;cb879;fen1", "protein_name": "Flap endonuclease 1", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "5'-3' exonuclease activity", "id": "GO:0008409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008409", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "5'-flap endonuclease activity", "id": "GO:0017108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017108", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" } ], "biological_process": [ { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" }, { "name": "DNA replication, removal of RNA primer", "id": "GO:0043137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043137", "evidence": [ { "database": "UniProtKB", "id": "Q6TNU4", "url": "https://www.uniprot.org/uniprotkb/Q6TNU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6TNU4-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Thr372", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 372, "start_aa": "Thr", "end_pos": 372, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr372", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q6UFS5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q6UFS5", "url": "https://www.uniprot.org/uniprotkb/Q6UFS5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 563, "chemical_mass": 57925.0, "gene_names": "znf503;fc47h01;nlz2;noz2;wu:fc47h01;wu:fi34f11;znf503", "protein_name": "Zinc finger protein 503", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q6UFS5", "url": "https://www.uniprot.org/uniprotkb/Q6UFS5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q6UFS5", "url": "https://www.uniprot.org/uniprotkb/Q6UFS5" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q6UFS5", "url": "https://www.uniprot.org/uniprotkb/Q6UFS5" } ], "pmid": "" }, { "name": "hindbrain development", "id": "GO:0030902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030902", "evidence": [ { "database": "UniProtKB", "id": "Q6UFS5", "url": "https://www.uniprot.org/uniprotkb/Q6UFS5" } ], "pmid": "" }, { "name": "embryonic camera-type eye morphogenesis", "id": "GO:0048596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048596", "evidence": [ { "database": "UniProtKB", "id": "Q6UFS5", "url": "https://www.uniprot.org/uniprotkb/Q6UFS5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q6UFS5", "url": "https://www.uniprot.org/uniprotkb/Q6UFS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q6UFS5-1", "start_pos": "529", "end_pos": "529", "site_lbl": "Thr529", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 529, "start_aa": "Thr", "end_pos": 529, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr529", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q708S3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q708S3", "url": "https://www.uniprot.org/uniprotkb/Q708S3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 558, "chemical_mass": 62448.0, "gene_names": "asic4b;ASIC4-B;ASIC4;accn4b;asic4b;zASIC4.2;zgc:111839", "protein_name": "Acid-sensing ion channel 4-B", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:14452", "name": "hypokalemic periodic paralysis", "description": "", "url": "https://disease-ontology.org/term/DOID:14452", "evidence": [ { "id": "14452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14452" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q708S3", "url": "https://www.uniprot.org/uniprotkb/Q708S3" } ], "pmid": "" } ], "biological_process": [ { "name": "response to steroid hormone", "id": "GO:0048545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048545", "evidence": [ { "database": "UniProtKB", "id": "Q708S3", "url": "https://www.uniprot.org/uniprotkb/Q708S3" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q708S3", "url": "https://www.uniprot.org/uniprotkb/Q708S3" } ], "pmid": "" } ], "molecular_function": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "Q708S3", "url": "https://www.uniprot.org/uniprotkb/Q708S3" } ], "pmid": "" }, { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "Q708S3", "url": "https://www.uniprot.org/uniprotkb/Q708S3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q708S3-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Asn140", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 140, "start_aa": "Asn", "end_pos": 140, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn140", "evidence": [ { "id": "Q708S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S3-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Asn183", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 183, "start_aa": "Asn", "end_pos": 183, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn183", "evidence": [ { "id": "Q708S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S3-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Asn188", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 188, "start_aa": "Asn", "end_pos": 188, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn188", "evidence": [ { "id": "Q708S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S3-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Asn210", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 210, "start_aa": "Asn", "end_pos": 210, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn210", "evidence": [ { "id": "Q708S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S3-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Asn245", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 245, "start_aa": "Asn", "end_pos": 245, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn245", "evidence": [ { "id": "Q708S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S3-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Asn374", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 374, "start_aa": "Asn", "end_pos": 374, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn374", "evidence": [ { "id": "Q708S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S3#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q708S4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q708S4", "url": "https://www.uniprot.org/uniprotkb/Q708S4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 539, "chemical_mass": 60814.0, "gene_names": "asic4a;ASIC4-A;ASIC4;accn4a;asic4a;zASIC4.1", "protein_name": "Acid-sensing ion channel 4-A", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:14452", "name": "hypokalemic periodic paralysis", "description": "", "url": "https://disease-ontology.org/term/DOID:14452", "evidence": [ { "id": "14452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14452" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q708S4", "url": "https://www.uniprot.org/uniprotkb/Q708S4" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "Q708S4", "url": "https://www.uniprot.org/uniprotkb/Q708S4" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q708S4", "url": "https://www.uniprot.org/uniprotkb/Q708S4" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated sodium channel activity", "id": "GO:0015280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015280", "evidence": [ { "database": "UniProtKB", "id": "Q708S4", "url": "https://www.uniprot.org/uniprotkb/Q708S4" } ], "pmid": "" }, { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "Q708S4", "url": "https://www.uniprot.org/uniprotkb/Q708S4" } ], "pmid": "" }, { "name": "voltage-gated sodium channel activity", "id": "GO:0005248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005248", "evidence": [ { "database": "UniProtKB", "id": "Q708S4", "url": "https://www.uniprot.org/uniprotkb/Q708S4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q708S4-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Asn136", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 136, "start_aa": "Asn", "end_pos": 136, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn136", "evidence": [ { "id": "Q708S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S4-1", "start_pos": "165", "end_pos": "165", "site_lbl": "Asn165", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 165, "start_aa": "Asn", "end_pos": 165, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn165", "evidence": [ { "id": "Q708S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S4-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Asn179", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 179, "start_aa": "Asn", "end_pos": 179, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn179", "evidence": [ { "id": "Q708S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S4-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Asn184", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 184, "start_aa": "Asn", "end_pos": 184, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn184", "evidence": [ { "id": "Q708S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S4-1", "start_pos": "206", "end_pos": "206", "site_lbl": "Asn206", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 206, "start_aa": "Asn", "end_pos": 206, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn206", "evidence": [ { "id": "Q708S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S4-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Asn241", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 241, "start_aa": "Asn", "end_pos": 241, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn241", "evidence": [ { "id": "Q708S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q708S4-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Asn370", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 370, "start_aa": "Asn", "end_pos": 370, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn370", "evidence": [ { "id": "Q708S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q708S4#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q71MM5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 267, "chemical_mass": 29092.0, "gene_names": "dmrt1;dmrt1;zgc:136676", "protein_name": "Doublesex- and mab-3-related transcription factor 1", "disease": [ { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" }, { "name": "germ cell development", "id": "GO:0007281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007281", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" }, { "name": "male germ cell proliferation", "id": "GO:0002176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002176", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" }, { "name": "male sex determination", "id": "GO:0030238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030238", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q71MM5", "url": "https://www.uniprot.org/uniprotkb/Q71MM5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q71PD7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q71PD7", "url": "https://www.uniprot.org/uniprotkb/Q71PD7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 128, "chemical_mass": 13509.0, "gene_names": "h2az2a;H2A.F/Z;h2afva;h2afv;h2afz;h2az2a;h2aza", "protein_name": "Histone H2A.V", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q71PD7", "url": "https://www.uniprot.org/uniprotkb/Q71PD7" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q71PD7", "url": "https://www.uniprot.org/uniprotkb/Q71PD7" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "Q71PD7", "url": "https://www.uniprot.org/uniprotkb/Q71PD7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q71PD7", "url": "https://www.uniprot.org/uniprotkb/Q71PD7" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "Q71PD7", "url": "https://www.uniprot.org/uniprotkb/Q71PD7" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of melanocyte differentiation", "id": "GO:0045636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045636", "evidence": [ { "database": "UniProtKB", "id": "Q71PD7", "url": "https://www.uniprot.org/uniprotkb/Q71PD7" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q71PD7", "url": "https://www.uniprot.org/uniprotkb/Q71PD7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SX85-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SX85", "url": "https://www.uniprot.org/uniprotkb/Q7SX85" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 714, "chemical_mass": 81274.0, "gene_names": "sestd1;HAPIP;cb248;dZ106A20.1;duo;sb:cb248;sestd1;si:dz106a20.1;si:dz106a20.2;si:dz42h5.2;solo;sol", "protein_name": "SEC14 domain and spectrin repeat-containing protein 1", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "evidence": [ { "database": "UniProtKB", "id": "Q7SX85", "url": "https://www.uniprot.org/uniprotkb/Q7SX85" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "Q7SX85", "url": "https://www.uniprot.org/uniprotkb/Q7SX85" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4-bisphosphate binding", "id": "GO:0043325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043325", "evidence": [ { "database": "UniProtKB", "id": "Q7SX85", "url": "https://www.uniprot.org/uniprotkb/Q7SX85" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "Q7SX85", "url": "https://www.uniprot.org/uniprotkb/Q7SX85" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "Q7SX85", "url": "https://www.uniprot.org/uniprotkb/Q7SX85" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "Q7SX85", "url": "https://www.uniprot.org/uniprotkb/Q7SX85" } ], "pmid": "" } ], "biological_process": [ { "name": "blood vessel morphogenesis", "id": "GO:0048514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048514", "evidence": [ { "database": "UniProtKB", "id": "Q7SX85", "url": "https://www.uniprot.org/uniprotkb/Q7SX85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXF1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 478, "chemical_mass": 55189.0, "gene_names": "dhcr7", "protein_name": "7-dehydrocholesterol reductase", "disease": [ { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:14692", "name": "Smith-Lemli-Opitz syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:14692", "evidence": [ { "id": "14692", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14692" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "7-dehydrocholesterol reductase activity", "id": "GO:0047598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047598", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor", "id": "GO:0016628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016628", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" }, { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" }, { "name": "behavioral fear response", "id": "GO:0001662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001662", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" }, { "name": "aggressive behavior", "id": "GO:0002118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002118", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q7SXF1", "url": "https://www.uniprot.org/uniprotkb/Q7SXF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXI1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 115, "chemical_mass": 12592.0, "gene_names": "cox7a2l;D244;cox7a2l;cox7a3;scaf1;wu:fp89f04;zgc:66312", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "disease": [ { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:3762", "name": "cytochrome-c oxidase deficiency disease", "description": "A mitochondrial metabolism disease that is characterized by deficiency of cytochrome c oxidase, myopathy, hepatomegaly, hypertrophic cardiomyopathy, lactic acidosis, and Leigh syndrome, and is caused by mutations related to oxidative phosphorylation.", "url": "https://disease-ontology.org/term/DOID:3762", "evidence": [ { "id": "3762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3762" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "pmid": "" }, { "name": "respiratory chain complex IV", "id": "GO:0045277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045277", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial electron transport, cytochrome c to oxygen", "id": "GO:0006123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006123", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "pmid": "" }, { "name": "regulation of oxidative phosphorylation", "id": "GO:0002082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002082", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "pmid": "" }, { "name": "mitochondrial respirasome assembly", "id": "GO:0097250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097250", "evidence": [ { "database": "UniProtKB", "id": "Q7SXI1", "url": "https://www.uniprot.org/uniprotkb/Q7SXI1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXJ6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 513, "chemical_mass": 56887.0, "gene_names": "rnf25;rnf25;zgc:66260", "protein_name": "E3 ubiquitin-protein ligase RNF25", "disease": [], "biological_process": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q7SXJ6", "url": "https://www.uniprot.org/uniprotkb/Q7SXJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXL3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 302, "chemical_mass": 33019.0, "gene_names": "tbp;fd20h06;si:ch211-202m22.5;si:zc101n13.2;tbp;wu:fd20h06;zgc:66213", "protein_name": "TATA-box-binding protein", "disease": [ { "disease_id": "DOID:0050847", "name": "sleep apnea", "description": "A sleep disorder characterized by repeated cessation and commencing of breathing that repeatedly disrupts sleep.", "url": "https://disease-ontology.org/term/DOID:0050847", "evidence": [ { "id": "0050847", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050847" } ], "weight": 0.0 }, { "disease_id": "DOID:0050967", "name": "spinocerebellar ataxia 17", "description": "An autosomal dominant cerebellar ataxia that is characterized by chorea, dementia, dystonia, spasiticity and seizure, has_material_basis_in CAG repeat expansion in the TBP gene.", "url": "https://disease-ontology.org/term/DOID:0050967", "evidence": [ { "id": "0050967", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050967" } ], "weight": 0.0 }, { "disease_id": "DOID:0060892", "name": "late onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.", "url": "https://disease-ontology.org/term/DOID:0060892", "evidence": [ { "id": "0060892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060892" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" } ], "biological_process": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" }, { "name": "gastrulation", "id": "GO:0007369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007369", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" }, { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL3", "url": "https://www.uniprot.org/uniprotkb/Q7SXL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7SXL3-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Thr113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 113, "start_aa": "Thr", "end_pos": 113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr113", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXL7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 423, "chemical_mass": 46152.0, "gene_names": "wtap;ch211-195e3.2;wtap;wu:fi29a09;zgc:66202", "protein_name": "Pre-mRNA-splicing regulator WTAP", "disease": [], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" }, { "name": "mRNA modification", "id": "GO:0016556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016556", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q7SXL7", "url": "https://www.uniprot.org/uniprotkb/Q7SXL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXP0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 215, "chemical_mass": 24689.0, "gene_names": "sec22bb;sec22bb;sec22l1b;wu:fd20b06", "protein_name": "Vesicle-trafficking protein SEC22b-B", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" }, { "name": "vesicle fusion with Golgi apparatus", "id": "GO:0048280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048280", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP0", "url": "https://www.uniprot.org/uniprotkb/Q7SXP0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXP2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXP2", "url": "https://www.uniprot.org/uniprotkb/Q7SXP2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 533, "chemical_mass": 60404.0, "gene_names": "nae1;appbp1;nae1;zgc:66148", "protein_name": "NEDD8-activating enzyme E1 regulatory subunit", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "NEDD8 activating enzyme activity", "id": "GO:0019781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019781", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP2", "url": "https://www.uniprot.org/uniprotkb/Q7SXP2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein neddylation", "id": "GO:0045116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045116", "evidence": [ { "database": "UniProtKB", "id": "Q7SXP2", "url": "https://www.uniprot.org/uniprotkb/Q7SXP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXS7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 596, "chemical_mass": 67251.0, "gene_names": "setd3;fb01d12;setd3;wu:fb01d12;zgc:63842", "protein_name": "Actin-histidine N-methyltransferase", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "protein-L-histidine N-tele-methyltransferase activity", "id": "GO:0018064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018064", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "actin modification", "id": "GO:0030047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030047", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "regulation of uterine smooth muscle contraction", "id": "GO:0070472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070472", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" }, { "name": "peptidyl-histidine methylation", "id": "GO:0018021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018021", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS7", "url": "https://www.uniprot.org/uniprotkb/Q7SXS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXS8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 348, "chemical_mass": 39935.0, "gene_names": "hpf1;fb44b08;hpf1;wu:fb44b08;zgc:101819", "protein_name": "Histone PARylation factor 1", "disease": [], "molecular_function": [ { "name": "poly-ADP-D-ribose binding", "id": "GO:0072572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072572", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" }, { "name": "protein ADP-ribosyltransferase-substrate adaptor activity", "id": "GO:0140768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140768", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" }, { "name": "DNA repair-dependent chromatin remodeling", "id": "GO:0140861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140861", "evidence": [ { "database": "UniProtKB", "id": "Q7SXS8", "url": "https://www.uniprot.org/uniprotkb/Q7SXS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXW4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 261, "chemical_mass": 29792.0, "gene_names": "emc3;emc3;pob;tmem111;wu:fi32f05;wu:fj63h08;zgc:63727", "protein_name": "ER membrane protein complex subunit 3", "disease": [ { "disease_id": "DOID:10155", "name": "intestinal cancer", "description": "A gastrointestinal system cancer that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:10155", "evidence": [ { "id": "10155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10155" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" } ], "biological_process": [ { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" }, { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "Q7SXW4", "url": "https://www.uniprot.org/uniprotkb/Q7SXW4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SXX7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 275, "chemical_mass": 29766.0, "gene_names": "mvb12a;fam125a;mvb12a;si:ch1073-286c18.3;zgc:63691", "protein_name": "Multivesicular body subunit 12A", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" }, { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" }, { "name": "receptor catabolic process", "id": "GO:0032801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032801", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" }, { "name": "regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042058", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" }, { "name": "viral budding", "id": "GO:0046755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046755", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" }, { "name": "endosome to lysosome transport via multivesicular body sorting pathway", "id": "GO:0032510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032510", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" }, { "name": "virus maturation", "id": "GO:0019075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019075", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" } ], "molecular_function": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "Q7SXX7", "url": "https://www.uniprot.org/uniprotkb/Q7SXX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SY06-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SY06", "url": "https://www.uniprot.org/uniprotkb/Q7SY06" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 359, "chemical_mass": 42412.0, "gene_names": "hacd3;HACD;hacd3;ptplad1;si:ch211-117i10.7;zgc:63632", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q7SY06", "url": "https://www.uniprot.org/uniprotkb/Q7SY06" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q7SY06", "url": "https://www.uniprot.org/uniprotkb/Q7SY06" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "Q7SY06", "url": "https://www.uniprot.org/uniprotkb/Q7SY06" } ], "pmid": "" }, { "name": "fatty acid elongation", "id": "GO:0030497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030497", "evidence": [ { "database": "UniProtKB", "id": "Q7SY06", "url": "https://www.uniprot.org/uniprotkb/Q7SY06" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "Q7SY06", "url": "https://www.uniprot.org/uniprotkb/Q7SY06" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-hydroxyacyl-CoA dehydratase activity", "id": "GO:0018812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018812", "evidence": [ { "database": "UniProtKB", "id": "Q7SY06", "url": "https://www.uniprot.org/uniprotkb/Q7SY06" } ], "pmid": "" }, { "name": "very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity", "id": "GO:0102158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102158", "evidence": [ { "database": "UniProtKB", "id": "Q7SY06", "url": "https://www.uniprot.org/uniprotkb/Q7SY06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SY10-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SY10", "url": "https://www.uniprot.org/uniprotkb/Q7SY10" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 484, "chemical_mass": 54687.0, "gene_names": "tmem161b;id:ibd2207;si:dkey-195m1.1;tmem161b;wu:fc31d04;zgc:63626", "protein_name": "Transmembrane protein 161B", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7SY10", "url": "https://www.uniprot.org/uniprotkb/Q7SY10" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of heart rate", "id": "GO:0002027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002027", "evidence": [ { "database": "UniProtKB", "id": "Q7SY10", "url": "https://www.uniprot.org/uniprotkb/Q7SY10" } ], "pmid": "" }, { "name": "regulation of cardiac muscle contraction by calcium ion signaling", "id": "GO:0010882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010882", "evidence": [ { "database": "UniProtKB", "id": "Q7SY10", "url": "https://www.uniprot.org/uniprotkb/Q7SY10" } ], "pmid": "" }, { "name": "regulation of cardiac muscle cell action potential", "id": "GO:0098901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098901", "evidence": [ { "database": "UniProtKB", "id": "Q7SY10", "url": "https://www.uniprot.org/uniprotkb/Q7SY10" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7SY10-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Asn136", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 136, "start_aa": "Asn", "end_pos": 136, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn136", "evidence": [ { "id": "Q7SY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7SY10#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q7SY10-1", "start_pos": "204", "end_pos": "204", "site_lbl": "Asn204", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 204, "start_aa": "Asn", "end_pos": 204, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn204", "evidence": [ { "id": "Q7SY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7SY10#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SY52-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 974, "chemical_mass": 113687.0, "gene_names": "stk10;zgc:63495", "protein_name": "Serine/threonine-protein kinase 10", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" }, { "name": "protein autophosphorylation", "id": "GO:0046777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046777", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" }, { "name": "regulation of lymphocyte migration", "id": "GO:2000401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000401", "evidence": [ { "database": "UniProtKB", "id": "Q7SY52", "url": "https://www.uniprot.org/uniprotkb/Q7SY52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SYI5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SYI5", "url": "https://www.uniprot.org/uniprotkb/Q7SYI5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 374, "chemical_mass": 43454.0, "gene_names": "c1galt1lb;c1galt1b;c1galt1lb;c1galt1;fa98f05;wu:fa98f05;zgc:66485", "protein_name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B", "disease": [ { "disease_id": "DOID:0060050", "name": "autoimmune disease of blood", "description": "An autoimmune disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the blood.", "url": "https://disease-ontology.org/term/DOID:0060050", "evidence": [ { "id": "0060050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060050" } ], "weight": 0.0 } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "Q7SYI5", "url": "https://www.uniprot.org/uniprotkb/Q7SYI5" } ], "pmid": "" }, { "name": "kidney development", "id": "GO:0001822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", "evidence": [ { "database": "UniProtKB", "id": "Q7SYI5", "url": "https://www.uniprot.org/uniprotkb/Q7SYI5" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q7SYI5", "url": "https://www.uniprot.org/uniprotkb/Q7SYI5" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q7SYI5", "url": "https://www.uniprot.org/uniprotkb/Q7SYI5" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q7SYI5", "url": "https://www.uniprot.org/uniprotkb/Q7SYI5" } ], "pmid": "" }, { "name": "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity", "id": "GO:0016263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016263", "evidence": [ { "database": "UniProtKB", "id": "Q7SYI5", "url": "https://www.uniprot.org/uniprotkb/Q7SYI5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SYK1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SYK1", "url": "https://www.uniprot.org/uniprotkb/Q7SYK1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 400, "chemical_mass": 44425.0, "gene_names": "qtrt1;qtrt1;zgc:66378", "protein_name": "Queuine tRNA-ribosyltransferase catalytic subunit 1", "disease": [], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q7SYK1", "url": "https://www.uniprot.org/uniprotkb/Q7SYK1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q7SYK1", "url": "https://www.uniprot.org/uniprotkb/Q7SYK1" } ], "pmid": "" }, { "name": "tRNA-guanosine(34) queuine transglycosylase activity", "id": "GO:0008479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008479", "evidence": [ { "database": "UniProtKB", "id": "Q7SYK1", "url": "https://www.uniprot.org/uniprotkb/Q7SYK1" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "Q7SYK1", "url": "https://www.uniprot.org/uniprotkb/Q7SYK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SZE5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 765, "chemical_mass": 86080.0, "gene_names": "sec23a;sec23a;wu:fc10f08;wu:fi15g03;zgc:55534", "protein_name": "Protein transport protein Sec23A", "disease": [ { "disease_id": "DOID:0070307", "name": "craniolenticulosutural dysplasia", "description": "A syndrome in neonates that is characterized by facial dysmorphism, late-closing fontanels, cataract, and skeletal defects. It has_material_basis_in the mutation of the SEC23A gene on the 14th chromosome, with the underproduction in the collagen secreting pathway and distension of endoplasmic reticulum leading to bone defects.", "url": "https://disease-ontology.org/term/DOID:0070307", "evidence": [ { "id": "0070307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070307" } ], "weight": 0.0 }, { "disease_id": "DOID:0111401", "name": "congenital dyserythropoietic anemia type II", "description": "A congenital dyserythropoietic anemia characterized by mild to severe anemia, bi- and multinucleated erythroblasts in bone marrow, jaundice and splenomegaly and may lead to liver iron overload and gallstones that has_material_basis_in homozygous or compound heterozygous mutation in the SEC23B gene on chromosome 20p11.23.", "url": "https://disease-ontology.org/term/DOID:0111401", "evidence": [ { "id": "0111401", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111401" } ], "weight": 0.0 }, { "disease_id": "DOID:5325", "name": "Roberts syndrome", "description": "A syndrome characterized by tetraphocomelia, craniofacial anomalies, growth retardation, intellectual disability, and cardiac and renal abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the ESCO2 gene on chromosome 8p21.1.", "url": "https://disease-ontology.org/term/DOID:5325", "evidence": [ { "id": "5325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5325" } ], "weight": 0.0 } ], "biological_process": [ { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "protein targeting", "id": "GO:0006605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "embryonic neurocranium morphogenesis", "id": "GO:0048702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048702", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "pectoral fin morphogenesis", "id": "GO:0035138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035138", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "Q7SZE5", "url": "https://www.uniprot.org/uniprotkb/Q7SZE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SZN2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SZN2", "url": "https://www.uniprot.org/uniprotkb/Q7SZN2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 266, "chemical_mass": 29628.0, "gene_names": "rnf170;rnf170;zgc:65779;zgc:76995", "protein_name": "E3 ubiquitin-protein ligase RNF170", "disease": [ { "disease_id": "DOID:0050951", "name": "hereditary ataxia", "description": "A neurodegenerative disease that is characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements.", "url": "https://disease-ontology.org/term/DOID:0050951", "evidence": [ { "id": "0050951", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050951" } ], "weight": 0.0 }, { "disease_id": "DOID:0111170", "name": "autosomal dominant sensory ataxia 1", "description": "A hereditary ataxia characterized by gait difficulty and instability especially in dark conditions resulting from sensory loss in the extremities and without cerebellar involvement that has_material_basis_in heterozygous mutations in the RNF170 gene on chromosome 8.", "url": "https://disease-ontology.org/term/DOID:0111170", "evidence": [ { "id": "0111170", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111170" } ], "weight": 0.0 }, { "disease_id": "DOID:0112345", "name": "hereditary spastic paraplegia 85", "description": "A hereditary spastic paraplegia characterized by onset of motor symptoms (e.g. spasticity and hyperreflexia of the lower limbs) in the first few years of life that has_material_basis_in homozygous or compound heterozygous mutation in the RNF170 gene on chromosome 8p11.21.", "url": "https://disease-ontology.org/term/DOID:0112345", "evidence": [ { "id": "0112345", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112345" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7SZN2", "url": "https://www.uniprot.org/uniprotkb/Q7SZN2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q7SZN2", "url": "https://www.uniprot.org/uniprotkb/Q7SZN2" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q7SZN2", "url": "https://www.uniprot.org/uniprotkb/Q7SZN2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q7SZN2", "url": "https://www.uniprot.org/uniprotkb/Q7SZN2" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q7SZN2", "url": "https://www.uniprot.org/uniprotkb/Q7SZN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SZQ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 467, "chemical_mass": 53317.0, "gene_names": "mboat7;leng4;mboat7;oact7;zgc:66032", "protein_name": "Membrane-bound acylglycerophosphatidylinositol O-acyltransferase mboat7", "disease": [ { "disease_id": "DOID:0081219", "name": "autosomal recessive intellectual developmental disorder 57", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the MBOAT7 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0081219", "evidence": [ { "id": "0081219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081219" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylcholine acyl-chain remodeling", "id": "GO:0036151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036151", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" }, { "name": "phosphatidylinositol biosynthetic process", "id": "GO:0006661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006661", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" }, { "name": "regulation of triglyceride metabolic process", "id": "GO:0090207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090207", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" }, { "name": "lipid modification", "id": "GO:0030258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030258", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" }, { "name": "phosphatidylinositol acyl-chain remodeling", "id": "GO:0036149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036149", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "lysophospholipid acyltransferase activity", "id": "GO:0071617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071617", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" }, { "name": "O-acyltransferase activity", "id": "GO:0008374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008374", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" }, { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "Q7SZQ0", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7SZQ0-1", "start_pos": "316", "end_pos": "316", "site_lbl": "Asn316", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 316, "start_aa": "Asn", "end_pos": 316, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn316", "evidence": [ { "id": "Q7SZQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7SZQ0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q7SZQ0-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Thr98", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 98, "start_aa": "Thr", "end_pos": 98, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr98", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7SZR5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 100, "chemical_mass": 11396.0, "gene_names": "sumo1;fd12c02;hm:zeh0670;sumo1;wu:fb74c02;wu:fd12c02;zgc:65934;zgc:85634", "protein_name": "Small ubiquitin-related modifier 1", "disease": [ { "disease_id": "DOID:0080403", "name": "orofacial cleft 10", "description": "An orofacial cleft that has_material_basis_in mutation in the SUMO1 gene on chromosome 2q33.", "url": "https://disease-ontology.org/term/DOID:0080403", "evidence": [ { "id": "0080403", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080403" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nuclear stress granule", "id": "GO:0097165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097165", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "cellular response to heat", "id": "GO:0034605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034605", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "cellular response to cadmium ion", "id": "GO:0071276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071276", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "chordate embryonic development", "id": "GO:0043009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043009", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" }, { "name": "protein tag activity", "id": "GO:0031386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031386", "evidence": [ { "database": "UniProtKB", "id": "Q7SZR5", "url": "https://www.uniprot.org/uniprotkb/Q7SZR5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7T2E8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 193, "chemical_mass": 21851.0, "gene_names": "rhoac;rhoac;wu:fc17g01;zgc:63939", "protein_name": "Rho-related GTP-binding protein RhoA-C", "disease": [ { "disease_id": "DOID:0050665", "name": "fetal alcohol syndrome", "description": "A fetal alcohol spectrum disorder that results in severe mental and physical defects which can develop in a child when the mother drinks alcohol during pregnancy. The presenting features include craniofacial dysmorphology (microcephaly, smooth philtrum, thin upper lip, small eye openings), pre- and postnatal growth deficiency, and central nervous system dysfunction.", "url": "https://disease-ontology.org/term/DOID:0050665", "evidence": [ { "id": "0050665", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050665" } ], "weight": 0.0 }, { "disease_id": "DOID:0080377", "name": "peroxisomal biogenesis disorder", "description": "A peroxisomal biogenesis disorder that has_material_basis_in defects in PEX genes.", "url": "https://disease-ontology.org/term/DOID:0080377", "evidence": [ { "id": "0080377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080377" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:4001", "name": "ovarian carcinoma", "description": "An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:4001", "evidence": [ { "id": "4001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4001" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9408", "name": "acute myocardial infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:9408", "evidence": [ { "id": "9408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9408" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "stress fiber assembly", "id": "GO:0043149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043149", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "skeletal muscle satellite cell migration", "id": "GO:1902766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902766", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" }, { "name": "wound healing, spreading of cells", "id": "GO:0044319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044319", "evidence": [ { "database": "UniProtKB", "id": "Q7T2E8", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7T2E8-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Tyr34", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "Y", "relation": "attached", "comment": "O-linked (GlcNAc) tyrosine;O-GlcNAcylation", "icn3d_view": {}, "start_pos": 34, "start_aa": "Tyr", "end_pos": 34, "end_aa": "Tyr", "residue": "Tyr", "site_lbl": "Tyr34", "evidence": [ { "id": "Q7T2E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T2E8#ptm_processing" }, { "id": "26190758", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/26190758" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7T2P6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 208, "chemical_mass": 21919.0, "gene_names": "timm23", "protein_name": "Mitochondrial import inner membrane translocase subunit Tim23", "disease": [ { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial intermembrane space chaperone complex", "id": "GO:0042719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042719", "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "pmid": "" }, { "name": "TIM23 mitochondrial import inner membrane translocase complex", "id": "GO:0005744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005744", "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "pmid": "" }, { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-transporting ATPase activity", "id": "GO:0015450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015450", "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "pmid": "" }, { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "Q7T2P6", "url": "https://www.uniprot.org/uniprotkb/Q7T2P6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "Q7T2V2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q7T2V2", "url": "https://www.uniprot.org/uniprotkb/Q7T2V2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 301, "chemical_mass": 35377.0, "gene_names": "sult1st3", "protein_name": "Cytosolic sulfotransferase 3", "disease": [ { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "Q7T2V2", "url": "https://www.uniprot.org/uniprotkb/Q7T2V2" } ], "pmid": "" }, { "name": "aryl sulfotransferase activity", "id": "GO:0004062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004062", "evidence": [ { "database": "UniProtKB", "id": "Q7T2V2", "url": "https://www.uniprot.org/uniprotkb/Q7T2V2" } ], "pmid": "" } ], "biological_process": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "Q7T2V2", "url": "https://www.uniprot.org/uniprotkb/Q7T2V2" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "Q7T2V2", "url": "https://www.uniprot.org/uniprotkb/Q7T2V2" } ], "pmid": "" }, { "name": "catecholamine metabolic process", "id": "GO:0006584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006584", "evidence": [ { "database": "UniProtKB", "id": "Q7T2V2", "url": "https://www.uniprot.org/uniprotkb/Q7T2V2" } ], "pmid": "" }, { "name": "steroid metabolic process", "id": "GO:0008202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008202", "evidence": [ { "database": "UniProtKB", "id": "Q7T2V2", "url": "https://www.uniprot.org/uniprotkb/Q7T2V2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7T2V2", "url": "https://www.uniprot.org/uniprotkb/Q7T2V2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q5U7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1113, "chemical_mass": 128402.0, "gene_names": "pik3cg;pik3cg;wu:fb15d07;zgc:77033", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "disease": [ { "disease_id": "DOID:0050211", "name": "swine influenza", "description": "An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus (Gammainfluenzavirus influenzae), or has_material_basis_in Influenza A virus (Alphainfluenzavirus influenzae) including subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea.", "url": "https://disease-ontology.org/term/DOID:0050211", "evidence": [ { "id": "0050211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050211" } ], "weight": 0.0 }, { "disease_id": "DOID:0061067", "name": "immunodeficiency 97", "description": "A T cell and NK cell immunodeficiency that is characterized by variable features and and that has_material_basis_in compound heterozygous mutation in the PIK3CG gene on chromosome 7q22.", "url": "https://disease-ontology.org/term/DOID:0061067", "evidence": [ { "id": "0061067", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061067" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 } ], "biological_process": [ { "name": "phosphatidylinositol-3-phosphate biosynthetic process", "id": "GO:0036092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036092", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "sphingosine-1-phosphate receptor signaling pathway", "id": "GO:0003376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003376", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "positive regulation of Rac protein signal transduction", "id": "GO:0035022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035022", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "neutrophil chemotaxis", "id": "GO:0030593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030593", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-3-kinase activity", "id": "GO:0016303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016303", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity", "id": "GO:0046934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046934", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 3-kinase activity", "id": "GO:0035005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035005", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class IB", "id": "GO:0005944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005944", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class IA", "id": "GO:0005943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005943", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5U7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5U7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q5X3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5X3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 391, "chemical_mass": 44167.0, "gene_names": "gjc4a.1;cx44.2;etID18867.6;fk18g12;gjc4a.1;gjc4a;wu:fk18g12", "protein_name": "Gap junction protein", "disease": [], "biological_process": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5X3" } ], "pmid": "" } ], "cellular_component": [ { "name": "connexin complex", "id": "GO:0005922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5X3" } ], "pmid": "" } ], "molecular_function": [ { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q5X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5X3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q613-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 657, "chemical_mass": 72187.0, "gene_names": "tesk1a;tesk1a", "protein_name": "dual-specificity kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" }, { "name": "protein serine/threonine/tyrosine kinase activity", "id": "GO:0004712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004712", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q613", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q713-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1478, "chemical_mass": 167668.0, "gene_names": "kdm5ba;id:ibd5050;jarid1ba;jarid1b;kdm5ba;wu:fd15c05", "protein_name": "[histone H3]-trimethyl-L-lysine(4) demethylase", "disease": [ { "disease_id": "DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms.", "url": "https://disease-ontology.org/term/DOID:0050888", "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060809", "name": "syndromic X-linked intellectual disability Claes-Jensen type", "description": "A syndromic X-linked intellectual disability characterized by severe intellectual deficit associated with variable clinical manifestations including spasticity, cryptorchidism, maxillary hypoplasia, alopecia areata, epilepsy, short stature, impaired speech and behavioral problems that has_material_basis_in mutation in the KDM5C gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060809", "evidence": [ { "id": "0060809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060809" } ], "weight": 0.0 }, { "disease_id": "DOID:0081226", "name": "autosomal recessive intellectual developmental disorder 65", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous or compound heterozygous mutation in the KDM5B gene on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081226", "evidence": [ { "id": "0081226", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081226" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:6039", "name": "uveal melanoma", "description": "A uveal cancer that has_material_basis_in uvea pigment cells.", "url": "https://disease-ontology.org/term/DOID:6039", "evidence": [ { "id": "6039", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6039" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "histone H3K4me/H3K4me2/H3K4me3 demethylase activity", "id": "GO:0034647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034647", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q713", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q713" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q7C5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1711, "chemical_mass": 191888.0, "gene_names": "lama3;lama3", "protein_name": "", "disease": [ { "disease_id": "DOID:0060738", "name": "junctional epidermolysis bullosa non-Herlitz type", "description": "A junctional epidermolysis bullosa characterized by skin and mucosal blistering, nail dystrophy or nail absence and enamel hypoplasia and that has_material_basis_in homozygous or compound heterozygous mutation in several genes including COL17A1, ITGB4 and the 3 genes that encode the subunits of laminin-5: LAMA3, LAMB3, and LAMC2. The non-Herlitz type is less severe than the related Herlitz type of junctional epidermolysis bullosa.", "url": "https://disease-ontology.org/term/DOID:0060738", "evidence": [ { "id": "0060738", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060738" } ], "weight": 0.0 }, { "disease_id": "DOID:3209", "name": "junctional epidermolysis bullosa", "description": "An epidermolysis bullosa that is characterized by recurrent blistering located in the lamina lucida of the basement membrane secondary to minor trauma, which can cause limited wounds, dehydration, electrolyte abnormalities, severe infection, among other issues, and has_material_basis_in mutation in genes related to laminin 332, which strengthens the skin.", "url": "https://disease-ontology.org/term/DOID:3209", "evidence": [ { "id": "3209", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3209" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "laminin complex", "id": "GO:0043256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043256", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" }, { "name": "basement membrane assembly", "id": "GO:0070831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070831", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7C5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7C5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9Q7C5-1", "start_pos": "1613", "end_pos": "1613", "site_lbl": "Thr1613", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1613, "start_aa": "Thr", "end_pos": 1613, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1613", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q7Y2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 489, "chemical_mass": 56049.0, "gene_names": "glra3;glra3;glyRalpha3", "protein_name": "", "disease": [], "molecular_function": [ { "name": "extracellularly glycine-gated ion channel activity", "id": "GO:0016933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016933", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity", "id": "GO:0022824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022824", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" }, { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" }, { "name": "glycine binding", "id": "GO:0016594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" }, { "name": "excitatory extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005231", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" } ], "cellular_component": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" } ], "biological_process": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q7Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q887-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 874, "chemical_mass": 97023.0, "gene_names": "clcn3;clcn3", "protein_name": "Chloride channel protein", "disease": [ { "disease_id": "DOID:0050699", "name": "Dent disease", "description": "A renal tubular transport disease that is characterized by tubular proteinuria, hypercalciuria, calcium nephrolithiasis, nephrocalcinosis and chronic kidney failure.", "url": "https://disease-ontology.org/term/DOID:0050699", "evidence": [ { "id": "0050699", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050699" } ], "weight": 0.0 }, { "disease_id": "DOID:0110731", "name": "neuronal ceroid lipofuscinosis 3", "description": "A neuronal ceroid lipofuscinosis that is characterized by juvenile-onset of progressive dementia, seizures, and progressive visual failure and an ultrastructural pattern of lipopigment with a 'fingerprint' profile and has_material_basis_in homozygous or compound heterozygous mutation in the CLN3 gene on chromosome 16p11.", "url": "https://disease-ontology.org/term/DOID:0110731", "evidence": [ { "id": "0110731", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110731" } ], "weight": 0.0 }, { "disease_id": "DOID:0111815", "name": "low molecular weight proteinuria with hypercalciuric nephrocalcinosis", "description": "A Dent disease characterized by elevated levels of low molecular weight proteins in the urine, hypercalciuria, and nephrocalcinosis that has_material_basis_in hemizygous or homozygous mutation in the CLCN5 gene on chromosome Xp11.22.", "url": "https://disease-ontology.org/term/DOID:0111815", "evidence": [ { "id": "0111815", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111815" } ], "weight": 0.0 }, { "disease_id": "DOID:13533", "name": "osteopetrosis", "description": "An osteosclerosis that has_material_basis_in lack of bone resorption which results_in abnormally hard and brittle bones.", "url": "https://disease-ontology.org/term/DOID:13533", "evidence": [ { "id": "13533", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13533" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "voltage-gated chloride channel activity", "id": "GO:0005247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005247", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "chloride:proton antiporter activity", "id": "GO:0062158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062158", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" } ], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q887", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q887" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9Q887-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Thr499", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 499, "start_aa": "Thr", "end_pos": 499, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr499", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q8E3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 180, "chemical_mass": 20381.0, "gene_names": "cryabb;cryab2;cryabb;fe37f08;wu:fe37f08;zgc:91937", "protein_name": "Alpha-crystallin B chain", "disease": [ { "disease_id": "DOID:0080093", "name": "adult-onset myofibrillar myopathy 2A", "description": "A myofibrillar myopathy that has_material_basis_in heterozygous mutation in the alpha-B-crystallin gene on chromosome 11q23.", "url": "https://disease-ontology.org/term/DOID:0080093", "evidence": [ { "id": "0080093", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080093" } ], "weight": 0.0 }, { "disease_id": "DOID:0080309", "name": "infantile-onset myofibrillar myopathy-2B", "description": "A myofibrillar myopathy that has_material_basis_in homozygous mutation in the CRYAB gene on chromosome 11q23.", "url": "https://disease-ontology.org/term/DOID:0080309", "evidence": [ { "id": "0080309", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080309" } ], "weight": 0.0 }, { "disease_id": "DOID:0110174", "name": "Charcot-Marie-Tooth disease axonal type 2L", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in mutation in the HSPB8 gene.", "url": "https://disease-ontology.org/term/DOID:0110174", "evidence": [ { "id": "0110174", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110174" } ], "weight": 0.0 }, { "disease_id": "DOID:0110250", "name": "cataract 16 multiple types", "description": "A cataract that has_material_basis_in heterozygous or homozygous mutation in the CRYAB gene on chromosome 11q.", "url": "https://disease-ontology.org/term/DOID:0110250", "evidence": [ { "id": "0110250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110250" } ], "weight": 0.0 }, { "disease_id": "DOID:0110450", "name": "dilated cardiomyopathy 1II", "description": "A dilated cardiomyopathy that has_material_basis_in mutation in the CRYAB gene on chromosome 11q23.", "url": "https://disease-ontology.org/term/DOID:0110450", "evidence": [ { "id": "0110450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110450" } ], "weight": 0.0 }, { "disease_id": "DOID:0111206", "name": "autosomal dominant distal hereditary motor neuronopathy 2", "description": "An autosomal dominant distal hereditary motor neuronopathy that is characterized by onset of slowly progressive distal limb weakness and atrophy with onset between 15 to 25 years of age and that has_material_basis_in heterozygous mutation in the gene encoding heat-shock 22-kD protein-8 (HSPB8) on chromosome 12q24.", "url": "https://disease-ontology.org/term/DOID:0111206", "evidence": [ { "id": "0111206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111206" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" } ], "biological_process": [ { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "response to heat", "id": "GO:0009408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009408", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "myofibril assembly", "id": "GO:0030239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030239", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "maintenance of lens transparency", "id": "GO:0036438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036438", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "negative regulation of metabolic process", "id": "GO:0009892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009892", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" }, { "name": "structural constituent of eye lens", "id": "GO:0005212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005212", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8E3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8E3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q925-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1210, "chemical_mass": 138049.0, "gene_names": "dhx8;dhx8", "protein_name": "ATP-dependent RNA helicase DHX8", "disease": [], "biological_process": [ { "name": "mRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0070054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070054", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" }, { "name": "primitive hemopoiesis", "id": "GO:0060215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060215", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q925", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q925" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q998-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1205, "chemical_mass": 137176.0, "gene_names": "atp8b5a;atp8b5a", "protein_name": "Phospholipid-transporting ATPase", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" }, { "name": "phosphatidylcholine flippase activity", "id": "GO:0140345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140345", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q998", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q998" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q9J2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 392, "chemical_mass": 43059.0, "gene_names": "ppm1aa;pp2ca2;ppm1aa", "protein_name": "Protein phosphatase 1A", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9J2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9J2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q9K2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9K2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9K2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 894, "chemical_mass": 100264.0, "gene_names": "map4k5;fl74c10;map4k5;wu:fl74c10;zgc:55719;zgc:55985", "protein_name": "Mitogen-activated protein kinase kinase kinase kinase", "disease": [ { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9K2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9K2" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase kinase activity", "id": "GO:0008349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008349", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9K2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9K2" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9K2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9K2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9K2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9K2" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9K2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9K2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q9P3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9P3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9P3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 433, "chemical_mass": 48138.0, "gene_names": "nudt12;nudt12;zgc:112020", "protein_name": "NAD-capped RNA hydrolase NUDT12", "disease": [], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9P3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9P3" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9P3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9P3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q9P3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q9P3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QA37-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QA37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QA37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 508, "chemical_mass": 56594.0, "gene_names": "pimr152;si:dkey-265c15.9;LOC110438963;pimr155;si:dkey-265c15.9", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QA37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QA37" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QA37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QA37" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QA37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QA37" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QA37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QA37" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QA37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QA37" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QAE5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QAE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QAE5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 480, "chemical_mass": 54869.0, "gene_names": "ephx5;ephx5", "protein_name": "Epoxide hydrolase", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 }, { "disease_id": "DOID:0060060", "name": "non-Hodgkin lymphoma", "description": "A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma.", "url": "https://disease-ontology.org/term/DOID:0060060", "evidence": [ { "id": "0060060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060060" } ], "weight": 0.0 }, { "disease_id": "DOID:0080001", "name": "bone disease", "description": "A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function.", "url": "https://disease-ontology.org/term/DOID:0080001", "evidence": [ { "id": "0080001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080001" } ], "weight": 0.0 }, { "disease_id": "DOID:10320", "name": "asbestosis", "description": "A pneumoconiosis caused by inhalation and retention of asbestos fibers.", "url": "https://disease-ontology.org/term/DOID:10320", "evidence": [ { "id": "10320", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10320" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:12449", "name": "aplastic anemia", "description": "A normocytic anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.", "url": "https://disease-ontology.org/term/DOID:12449", "evidence": [ { "id": "12449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12449" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1579", "name": "respiratory system disease", "description": "A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm.", "url": "https://disease-ontology.org/term/DOID:1579", "evidence": [ { "id": "1579", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1579" } ], "weight": 0.0 }, { "disease_id": "DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells.", "url": "https://disease-ontology.org/term/DOID:2355", "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3602", "name": "toxic encephalopathy", "description": "A nervous system disease that results from exposure to neurotoxicants and is characterized by an altered mental status, memory loss, and visual problems.", "url": "https://disease-ontology.org/term/DOID:3602", "evidence": [ { "id": "3602", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3602" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5022", "name": "aflatoxins-related hepatocellular carcinoma", "description": "", "url": "https://disease-ontology.org/term/DOID:5022", "evidence": [ { "id": "5022", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5022" } ], "weight": 0.0 }, { "disease_id": "DOID:705", "name": "Leber hereditary optic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:705", "evidence": [ { "id": "705", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:705" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QAE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QAE5" } ], "pmid": "" } ], "biological_process": [ { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QAE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QAE5" } ], "pmid": "" }, { "name": "arachidonate metabolic process", "id": "GO:0019369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019369", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QAE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QAE5" } ], "pmid": "" }, { "name": "epoxide metabolic process", "id": "GO:0097176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097176", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QAE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QAE5" } ], "pmid": "" } ], "molecular_function": [ { "name": "epoxide hydrolase activity", "id": "GO:0004301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004301", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QAE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QAE5" } ], "pmid": "" }, { "name": "cis-stilbene-oxide hydrolase activity", "id": "GO:0033961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033961", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QAE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QAE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QBN4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 4625, "chemical_mass": 512581.0, "gene_names": "pkd1a;pkd1a", "protein_name": "", "disease": [ { "disease_id": "DOID:0050770", "name": "polycystic liver disease", "description": "A liver disease that is characterized by the presence of multiple cysts located_in the liver.", "url": "https://disease-ontology.org/term/DOID:0050770", "evidence": [ { "id": "0050770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050770" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0110858", "name": "polycystic kidney disease 1", "description": "A autosomal dominant polycystic kidney disease that has_material_basis_in autosomal dominant inheritance of mutation in the PKD1 gene on chromosome 16p13.3.", "url": "https://disease-ontology.org/term/DOID:0110858", "evidence": [ { "id": "0110858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110858" } ], "weight": 0.0 }, { "disease_id": "DOID:0110861", "name": "autosomal recessive polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion.", "url": "https://disease-ontology.org/term/DOID:0110861", "evidence": [ { "id": "0110861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110861" } ], "weight": 0.0 }, { "disease_id": "DOID:10941", "name": "intracranial aneurysm", "description": "", "url": "https://disease-ontology.org/term/DOID:10941", "evidence": [ { "id": "10941", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10941" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:898", "name": "autosomal dominant polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion.", "url": "https://disease-ontology.org/term/DOID:898", "evidence": [ { "id": "898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:898" } ], "weight": 0.0 } ], "biological_process": [ { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transport", "id": "GO:0098655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098655", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "pmid": "" }, { "name": "lymphangiogenesis", "id": "GO:0001946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001946", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "pmid": "" }, { "name": "pronephros development", "id": "GO:0048793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048793", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "pmid": "" }, { "name": "regulation of collagen biosynthetic process", "id": "GO:0032965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032965", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QBN4-1", "start_pos": "2140", "end_pos": "2140", "site_lbl": "Thr2140", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2140, "start_aa": "Thr", "end_pos": 2140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2140", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QBN4-1", "start_pos": "2144", "end_pos": "2144", "site_lbl": "Thr2144", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2144, "start_aa": "Thr", "end_pos": 2144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2144", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QBN4-1", "start_pos": "4281", "end_pos": "4281", "site_lbl": "Thr4281", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4281, "start_aa": "Thr", "end_pos": 4281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4281", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QBN4-1", "start_pos": "4543", "end_pos": "4543", "site_lbl": "Thr4543", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4543, "start_aa": "Thr", "end_pos": 4543, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4543", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QBN4-1", "start_pos": "960", "end_pos": "960", "site_lbl": "Thr960", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 960, "start_aa": "Thr", "end_pos": 960, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr960", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QBU0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 844, "chemical_mass": 94919.0, "gene_names": "nlgn4xa;nlgn4a;nlgn4b;nlgn4xa", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU0" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU0" } ], "pmid": "" } ], "cellular_component": [ { "name": "postsynaptic specialization membrane", "id": "GO:0099634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU0" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QBU1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 624, "chemical_mass": 68324.0, "gene_names": "clpxa;clpxa;clpx;fb93b07;wu:fb93b07;zgc:92303", "protein_name": "ATP-dependent clpX-like chaperone, mitochondrial", "disease": [ { "disease_id": "DOID:13270", "name": "erythropoietic protoporphyria", "description": "An acute porphyria characterized by a deficiency in the enzyme ferrochelatase, leading to abnormally high levels of protoporphyrin in the tissue.", "url": "https://disease-ontology.org/term/DOID:13270", "evidence": [ { "id": "13270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13270" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" }, { "name": "ATP-dependent protein folding chaperone", "id": "GO:0140662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140662", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" } ], "biological_process": [ { "name": "erythrocyte development", "id": "GO:0048821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048821", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QBU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBU1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9Q4U3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q4U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q4U3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1867, "chemical_mass": 205619.0, "gene_names": "pcsk5a;pcsk5a", "protein_name": "", "disease": [ { "disease_id": "DOID:0050545", "name": "visceral heterotaxy", "description": "A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.", "url": "https://disease-ontology.org/term/DOID:0050545", "evidence": [ { "id": "0050545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050545" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:14679", "name": "VACTERL association", "description": "A syndrome that is characterized by the presence of at least three of the following: vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities.", "url": "https://disease-ontology.org/term/DOID:14679", "evidence": [ { "id": "14679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14679" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q4U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q4U3" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q4U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q4U3" } ], "pmid": "" }, { "name": "neuromast development", "id": "GO:0048884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048884", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q4U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q4U3" } ], "pmid": "" }, { "name": "anterior lateral line development", "id": "GO:0048899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048899", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q4U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q4U3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9Q4U3-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Thr188", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9Q4U3-1", "start_pos": "830", "end_pos": "830", "site_lbl": "Thr830", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 830, "start_aa": "Thr", "end_pos": 830, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr830", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UV98-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV98", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV98" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2721, "chemical_mass": 301704.0, "gene_names": "tenm1;tenm1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV98", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV98" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV98", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV98" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV98", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV98" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV98", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV98" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV98", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV98" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV98", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV98" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV98", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV98" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7UV98-1", "start_pos": "1748", "end_pos": "1748", "site_lbl": "Thr1748", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1748, "start_aa": "Thr", "end_pos": 1748, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1748", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B8JI08-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1022, "chemical_mass": 115670.0, "gene_names": "ogdha;im:7045267;ogdh;wu:fa06d01;wu:fb98a04;zgc:73296", "protein_name": "2-oxoglutarate dehydrogenase complex component E1", "disease": [ { "disease_id": "DOID:0070468", "name": "Yoon-Bellen neurodevelopmental syndrome", "description": "A syndrome characterized by onset in the first decade of highly variable neurodevelopmental phenotypes including global developmental delay, intellectual disability, seizures, hearing and visual problems, and ataxia that has_material_basis_in homozygous or compound heterozygous mutation in the OGDHL gene on chromosome 10q11.23.", "url": "https://disease-ontology.org/term/DOID:0070468", "evidence": [ { "id": "0070468", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070468" } ], "weight": 0.0 }, { "disease_id": "DOID:0081326", "name": "oxoglutarate dehydrogenase deficiency", "description": "An amino acid metabolic disorder that is characterized by infantile and pediatric onset basal ganglia-associated movement disorders, hypotonia, developmental delays, ataxia, and seizures and that has_material_basis_in homozygous mutation in the oxoglutarate dehydrogenase gene (OGDH) on chromosome 7p13.", "url": "https://disease-ontology.org/term/DOID:0081326", "evidence": [ { "id": "0081326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081326" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" }, { "name": "oxoglutarate dehydrogenase complex", "id": "GO:0045252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045252", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" }, { "name": "thiamine pyrophosphate binding", "id": "GO:0030976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030976", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" }, { "name": "oxoglutarate dehydrogenase (succinyl-transferring) activity", "id": "GO:0004591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004591", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" } ], "biological_process": [ { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" }, { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" }, { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "B8JI08", "url": "https://www.uniprot.org/uniprotkb/B8JI08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QG12-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1898, "chemical_mass": 213811.0, "gene_names": "kif1aa;kif1aa", "protein_name": "plus-end-directed kinesin ATPase", "disease": [ { "disease_id": "DOID:0050548", "name": "hereditary sensory and autonomic neuropathy", "description": "A neuropathy characterized by axonal atrophy and degeneration, exclusively or predominantly affecting the sensory neurons, and variable autonomic dysfunction that has_material_basis_in an inherited mutation. Loss of pain and temperature sensation is an early and predominant, but not universal, symptom.", "url": "https://disease-ontology.org/term/DOID:0050548", "evidence": [ { "id": "0050548", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050548" } ], "weight": 0.0 }, { "disease_id": "DOID:0050890", "name": "synucleinopathy", "description": "A neurodegenerative disease that is characterized by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells.", "url": "https://disease-ontology.org/term/DOID:0050890", "evidence": [ { "id": "0050890", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050890" } ], "weight": 0.0 }, { "disease_id": "DOID:0070039", "name": "NESCAV syndrome", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the KIF1A gene on chromosome 2q37.3.", "url": "https://disease-ontology.org/term/DOID:0070039", "evidence": [ { "id": "0070039", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070039" } ], "weight": 0.0 }, { "disease_id": "DOID:0070147", "name": "hereditary sensory neuropathy type 2C", "description": "A hereditary sensory and autonomic neuropathy type 2 characterized by peripheral nerve degeneration and progressive distal sensory loss that has_material_basis_in homozygous or compound heterozygous mutation in the KIF1A gene on chromosome 2q37.", "url": "https://disease-ontology.org/term/DOID:0070147", "evidence": [ { "id": "0070147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070147" } ], "weight": 0.0 }, { "disease_id": "DOID:0070646", "name": "hereditary spastic paraplegia 30B", "description": "A hereditary spastic paraplegia 30 that has_material_basis_in homozygous mutation in the KIF1A gene on chromosome 2q37.", "url": "https://disease-ontology.org/term/DOID:0070646", "evidence": [ { "id": "0070646", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070646" } ], "weight": 0.0 }, { "disease_id": "DOID:0070647", "name": "hereditary spastic paraplegia 30A", "description": "A hereditary spastic paraplegia 30 that has_material_basis_in heterozygous mutation in the KIF1A gene on chromosome 2q37.", "url": "https://disease-ontology.org/term/DOID:0070647", "evidence": [ { "id": "0070647", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070647" } ], "weight": 0.0 }, { "disease_id": "DOID:0081120", "name": "Graves ophthalmopathy", "description": "An autoimmune disease of eyes, ear, nose and throat that is characterized by upper eyelid retraction, lid lag, swelling, redness, conjunctivitis, and bulging eyes.", "url": "https://disease-ontology.org/term/DOID:0081120", "evidence": [ { "id": "0081120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081120" } ], "weight": 0.0 }, { "disease_id": "DOID:0110781", "name": "hereditary spastic paraplegia 30", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the KIF1A gene on chromosome 2q37.", "url": "https://disease-ontology.org/term/DOID:0110781", "evidence": [ { "id": "0110781", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110781" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 }, { "disease_id": "DOID:863", "name": "nervous system disease", "description": "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.", "url": "https://disease-ontology.org/term/DOID:863", "evidence": [ { "id": "863", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:863" } ], "weight": 0.0 } ], "biological_process": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "pmid": "" }, { "name": "transport along microtubule", "id": "GO:0010970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010970", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG12" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QG12-1", "start_pos": "906", "end_pos": "906", "site_lbl": "Thr906", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 906, "start_aa": "Thr", "end_pos": 906, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr906", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TB31-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 906, "chemical_mass": 102353.0, "gene_names": "grik1b;grik1b", "protein_name": "Glutamate receptor", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1825", "name": "childhood absence epilepsy", "description": "A childhood electroclinical syndrome that is characterized by brief and frequent absence seizures in children with age of onset between four and ten years.", "url": "https://disease-ontology.org/term/DOID:1825", "evidence": [ { "id": "1825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1825" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" }, { "name": "kainate selective glutamate receptor activity", "id": "GO:0015277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015277", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" } ], "cellular_component": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" }, { "name": "kainate selective glutamate receptor complex", "id": "GO:0032983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032983", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" } ], "biological_process": [ { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TB31", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TB31" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QFI7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 841, "chemical_mass": 93004.0, "gene_names": "ddx3xa;ddx3a;ddx3xa;ddx3;fb74g09;wu:fb74g09;zgc:158804", "protein_name": "RNA helicase", "disease": [ { "disease_id": "DOID:0050457", "name": "Sertoli cell-only syndrome", "description": "A male infertility disease characterized by male sterility, has_material_basis_in azospermia without abnormal sexual development.", "url": "https://disease-ontology.org/term/DOID:0050457", "evidence": [ { "id": "0050457", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050457" } ], "weight": 0.0 }, { "disease_id": "DOID:0060309", "name": "syndromic X-linked intellectual disability", "description": "A syndromic intellectual disability characterized by an X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060309", "evidence": [ { "id": "0060309", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060309" } ], "weight": 0.0 }, { "disease_id": "DOID:3869", "name": "childhood medulloblastoma", "description": "", "url": "https://disease-ontology.org/term/DOID:3869", "evidence": [ { "id": "3869", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3869" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7USR7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1976, "chemical_mass": 229377.0, "gene_names": "myh10;myh10", "protein_name": "", "disease": [ { "disease_id": "DOID:0060651", "name": "MYH-9 related disease", "description": "A blood platelet disease that has_material_basis_in mutations in the MYH9 gene. It is characterized by thrombocytopenia, enlarged platelets, sensorineural hearing loss and presenile cataract.", "url": "https://disease-ontology.org/term/DOID:0060651", "evidence": [ { "id": "0060651", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060651" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "supramolecular fiber", "id": "GO:0099512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099512", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" } ], "biological_process": [ { "name": "midbrain-hindbrain boundary morphogenesis", "id": "GO:0021555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021555", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "actin filament bundle distribution", "id": "GO:0070650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070650", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7USR7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7USR7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7T720-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1364, "chemical_mass": 146676.0, "gene_names": "atp7b;atp7b", "protein_name": "Copper-transporting ATPase 2", "disease": [ { "disease_id": "DOID:0111272", "name": "occipital horn syndrome", "description": "A metal metabolism disorder characterized by hyperelastic and bruisable skin, hernias, bladder diverticula, hyperextensible joints, varicosities, abnormal copper transport, and multiple skeletal abnormalities that has_material_basis_in X-linked recessive inheritance of mutations in ATP7A on Xq21.1. This disorder is allelic to Menkes disease.", "url": "https://disease-ontology.org/term/DOID:0111272", "evidence": [ { "id": "0111272", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111272" } ], "weight": 0.0 }, { "disease_id": "DOID:12377", "name": "spinal muscular atrophy", "description": "A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.", "url": "https://disease-ontology.org/term/DOID:12377", "evidence": [ { "id": "12377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12377" } ], "weight": 0.0 }, { "disease_id": "DOID:1838", "name": "Menkes disease", "description": "", "url": "https://disease-ontology.org/term/DOID:1838", "evidence": [ { "id": "1838", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1838" } ], "weight": 0.0 }, { "disease_id": "DOID:2697", "name": "renal adenoma", "description": "", "url": "https://disease-ontology.org/term/DOID:2697", "evidence": [ { "id": "2697", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2697" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:686", "name": "liver carcinoma", "description": "A liver cancer that has_material_basis_in epithelial cells.", "url": "https://disease-ontology.org/term/DOID:686", "evidence": [ { "id": "686", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:686" } ], "weight": 0.0 }, { "disease_id": "DOID:893", "name": "Wilson disease", "description": "A metal metabolism disease that is characterized by excess copper stored in various body tissues, particularly the liver, brain, and corneas of the eyes.", "url": "https://disease-ontology.org/term/DOID:893", "evidence": [ { "id": "893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:893" } ], "weight": 0.0 }, { "disease_id": "DOID:896", "name": "metal metabolism disorder", "description": "An inherited metabolic disorder that involves metabolic disturbances in the processing or distribution of dietary minerals.", "url": "https://disease-ontology.org/term/DOID:896", "evidence": [ { "id": "896", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:896" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "P-type monovalent copper transporter activity", "id": "GO:0140581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140581", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "P-type divalent copper transporter activity", "id": "GO:0043682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043682", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular copper ion homeostasis", "id": "GO:0006878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006878", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "copper ion import", "id": "GO:0015677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015677", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" }, { "name": "copper ion export", "id": "GO:0060003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060003", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T720", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T720" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QFT7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1264, "chemical_mass": 141157.0, "gene_names": "dctn1b;dctn1b", "protein_name": "Dynactin subunit 1", "disease": [ { "disease_id": "DOID:0050890", "name": "synucleinopathy", "description": "A neurodegenerative disease that is characterized by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells.", "url": "https://disease-ontology.org/term/DOID:0050890", "evidence": [ { "id": "0050890", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050890" } ], "weight": 0.0 }, { "disease_id": "DOID:0060193", "name": "amyotrophic lateral sclerosis type 1", "description": "An amyotrophic lateral sclerosis that has_material_basis_in mutation in the SOD1 gene on chromosome 21. The most common type of familial ALS.", "url": "https://disease-ontology.org/term/DOID:0060193", "evidence": [ { "id": "0060193", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060193" } ], "weight": 0.0 }, { "disease_id": "DOID:0060486", "name": "Perry syndrome", "description": "A syndrome characterized by parkinsonism, hypoventilation, depression, and weight loss and that has_material_basis_in heterozygous mutation in the DCTN1 gene on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0060486", "evidence": [ { "id": "0060486", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060486" } ], "weight": 0.0 }, { "disease_id": "DOID:0111202", "name": "autosomal dominant distal hereditary motor neuronopathy 14", "description": "An autosomal dominant distal hereditary motor neuronopathy that has_material_basis_in heterozygous mutation in the DCTN1 gene on 2p13.1.", "url": "https://disease-ontology.org/term/DOID:0111202", "evidence": [ { "id": "0111202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111202" } ], "weight": 0.0 }, { "disease_id": "DOID:231", "name": "motor neuron disease", "description": "A neurodegenerative disease that is located_in the motor neurons.", "url": "https://disease-ontology.org/term/DOID:231", "evidence": [ { "id": "231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:231" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "camera-type eye photoreceptor cell differentiation", "id": "GO:0060219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060219", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QFT7-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Thr179", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7T870-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2953, "chemical_mass": 331474.0, "gene_names": "chd6;chd6", "protein_name": "", "disease": [ { "disease_id": "DOID:0050834", "name": "CHARGE syndrome", "description": "A syndrome that is characterized by a pattern of congenital anomalies including choanal atresia and malformations of the heart, inner ear, and retina.", "url": "https://disease-ontology.org/term/DOID:0050834", "evidence": [ { "id": "0050834", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050834" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T870", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T870" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7T870-1", "start_pos": "2485", "end_pos": "2485", "site_lbl": "Thr2485", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2485, "start_aa": "Thr", "end_pos": 2485, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2485", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QDG2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDG2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1314, "chemical_mass": 150059.0, "gene_names": "mink1;mink1;msn3;si:ch211-147a23.2;zgc:162163", "protein_name": "non-specific serine/threonine protein kinase", "disease": [ { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDG2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDG2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDG2" } ], "pmid": "" } ], "biological_process": [ { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDG2" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDG2" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDG2" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QDG2-1", "start_pos": "643", "end_pos": "643", "site_lbl": "Thr643", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 643, "start_aa": "Thr", "end_pos": 643, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr643", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QDG2-1", "start_pos": "645", "end_pos": "645", "site_lbl": "Thr645", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 645, "start_aa": "Thr", "end_pos": 645, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr645", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0S6L0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1578, "chemical_mass": 178661.0, "gene_names": "kdm5c;im:7158173;jarid1c;kdm5c;si:ch211-218o21.2;wu:fa28h03;wu:fi31b07", "protein_name": "Lysine-specific demethylase 5D", "disease": [ { "disease_id": "DOID:0060809", "name": "syndromic X-linked intellectual disability Claes-Jensen type", "description": "A syndromic X-linked intellectual disability characterized by severe intellectual deficit associated with variable clinical manifestations including spasticity, cryptorchidism, maxillary hypoplasia, alopecia areata, epilepsy, short stature, impaired speech and behavioral problems that has_material_basis_in mutation in the KDM5C gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060809", "evidence": [ { "id": "0060809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060809" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:12190", "name": "descending colon cancer", "description": "", "url": "https://disease-ontology.org/term/DOID:12190", "evidence": [ { "id": "12190", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12190" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "histone H3K4me/H3K4me2/H3K4me3 demethylase activity", "id": "GO:0034647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034647", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "B0S6L0", "url": "https://www.uniprot.org/uniprotkb/B0S6L0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TBA8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1155, "chemical_mass": 131510.0, "gene_names": "adcy2a;adcy2a", "protein_name": "adenylate cyclase", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 } ], "biological_process": [ { "name": "atrioventricular canal development", "id": "GO:0036302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036302", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" }, { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" }, { "name": "determination of heart left/right asymmetry", "id": "GO:0061371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061371", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" } ], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TBA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TBA8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7TBA8-1", "start_pos": "1018", "end_pos": "1018", "site_lbl": "Thr1018", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1018, "start_aa": "Thr", "end_pos": 1018, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1018", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7T6T3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 976, "chemical_mass": 109568.0, "gene_names": "bicd1a;bicd1a", "protein_name": "", "disease": [ { "disease_id": "DOID:0070349", "name": "spinal muscular atrophy with lower extremity predominant 2A", "description": "A spinal muscular atrophy with lower extremity predominance that is characterized by early childhood onset of muscle weakness and atrophy predominantly affecting the proximal and distal muscles of the lower extremity, although some patients may show upper extremity involvement and that has_material_basis_in heterozygous mutation in the BICD2 gene on chromosome 9q22.", "url": "https://disease-ontology.org/term/DOID:0070349", "evidence": [ { "id": "0070349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070349" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "cytoskeletal anchor activity", "id": "GO:0008093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008093", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "dynein complex binding", "id": "GO:0070840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070840", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "cargo adaptor activity", "id": "GO:0140312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140312", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "dynactin binding", "id": "GO:0034452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034452", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" } ], "biological_process": [ { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "regulation of retrograde axon cargo transport", "id": "GO:2001017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001017", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "positive regulation of receptor-mediated endocytosis", "id": "GO:0048260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048260", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "microtubule anchoring at microtubule organizing center", "id": "GO:0072393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072393", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6T3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6T3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7T6T3-1", "start_pos": "853", "end_pos": "853", "site_lbl": "Thr853", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 853, "start_aa": "Thr", "end_pos": 853, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr853", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QJR2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1645, "chemical_mass": 171360.0, "gene_names": "col18a1a;cb371;cb529;col18a1a;col18a1;fc96d06;sb:cb529;wu:fb47h10;wu:fb77g12;wu:fc50f04;wu:fc96d06;wu:fk02h12", "protein_name": "Collagen alpha-1(XVIII) chain", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:0060680", "name": "pigment dispersion syndrome", "description": "An eye disease characterized by slit-like depigmented areas of the iris with up to 50% of patients going on to develop glaucoma.", "url": "https://disease-ontology.org/term/DOID:0060680", "evidence": [ { "id": "0060680", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060680" } ], "weight": 0.0 }, { "disease_id": "DOID:10808", "name": "gastric ulcer", "description": "", "url": "https://disease-ontology.org/term/DOID:10808", "evidence": [ { "id": "10808", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10808" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1405", "name": "primary angle-closure glaucoma", "description": "An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.", "url": "https://disease-ontology.org/term/DOID:1405", "evidence": [ { "id": "1405", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1405" } ], "weight": 0.0 }, { "disease_id": "DOID:423", "name": "myopathy", "description": "A muscular disease in which the muscle fibers do not function resulting in muscular weakness.", "url": "https://disease-ontology.org/term/DOID:423", "evidence": [ { "id": "423", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:423" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:699", "name": "mitochondrial myopathy", "description": "A myopathy that is characterized by mitochondrial dysfunction.", "url": "https://disease-ontology.org/term/DOID:699", "evidence": [ { "id": "699", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:699" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" }, { "name": "glomerular basement membrane development", "id": "GO:0032836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032836", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QJR2-1", "start_pos": "1250", "end_pos": "1250", "site_lbl": "Thr1250", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1250, "start_aa": "Thr", "end_pos": 1250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1250", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QJR2-1", "start_pos": "1446", "end_pos": "1446", "site_lbl": "Thr1446", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1446, "start_aa": "Thr", "end_pos": 1446, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1446", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QJR2-1", "start_pos": "387", "end_pos": "387", "site_lbl": "Thr387", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 387, "start_aa": "Thr", "end_pos": 387, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr387", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QJR2-1", "start_pos": "50", "end_pos": "50", "site_lbl": "Thr50", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QJR2-1", "start_pos": "553", "end_pos": "553", "site_lbl": "Thr553", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 553, "start_aa": "Thr", "end_pos": 553, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr553", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QKY4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1614, "chemical_mass": 181082.0, "gene_names": "depdc5;depdc5", "protein_name": "", "disease": [ { "disease_id": "DOID:0081421", "name": "familial focal epilepsy with variable foci 1", "description": "A familial focal epilepsy with variable foci that is characterized by focal seizures arising from different cortical regions in different family members and that has_material_basis_in heterozygous mutation in the DEPDC5 gene on chromosome 22q12.", "url": "https://disease-ontology.org/term/DOID:0081421", "evidence": [ { "id": "0081421", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081421" } ], "weight": 0.0 }, { "disease_id": "DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood.", "url": "https://disease-ontology.org/term/DOID:0112202", "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:2234", "name": "focal epilepsy", "description": "An epilepsy syndrome that is characterized by seizures that are preceded by an isolated disturbance of a cerebral function and arise from an epileptic focus, a small portion of the brain that serves as the irritant driving the epileptic response.", "url": "https://disease-ontology.org/term/DOID:2234", "evidence": [ { "id": "2234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2234" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" }, { "name": "neuronal action potential propagation", "id": "GO:0019227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019227", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" }, { "name": "regulation of neuronal action potential", "id": "GO:0098908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098908", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" }, { "name": "thigmotaxis", "id": "GO:0001966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001966", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" }, { "name": "GATOR1 complex", "id": "GO:1990130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990130", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QKY4-1", "start_pos": "1160", "end_pos": "1160", "site_lbl": "Thr1160", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1160, "start_aa": "Thr", "end_pos": 1160, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1160", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CEJ3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 989, "chemical_mass": 110850.0, "gene_names": "ephb2b;ephb2b;fi18g12;tpx2;wu:fb09e10;wu:fc64a03;wu:fi18g12;zgc:112296", "protein_name": "receptor protein-tyrosine kinase", "disease": [ { "disease_id": "DOID:1561", "name": "cognitive disorder", "description": "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.", "url": "https://disease-ontology.org/term/DOID:1561", "evidence": [ { "id": "1561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1561" } ], "weight": 0.0 }, { "disease_id": "DOID:2218", "name": "blood platelet disease", "description": "A blood coagulation disease that is characterized by an abnormal increase or decrease in platelets or platelet dysfunction.", "url": "https://disease-ontology.org/term/DOID:2218", "evidence": [ { "id": "2218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2218" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" }, { "name": "ephrin receptor activity", "id": "GO:0005003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005003", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" }, { "name": "transmembrane-ephrin receptor activity", "id": "GO:0005005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005005", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" }, { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A2CEJ3", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0S6S7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 524, "chemical_mass": 59690.0, "gene_names": "etv5a;etv5a;etv5;fj87h10;id:ibd5133;wu:fj87h10;zgc:55647", "protein_name": "", "disease": [ { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "hemangioblast cell differentiation", "id": "GO:0060217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060217", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" }, { "name": "limb morphogenesis", "id": "GO:0035108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035108", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" }, { "name": "pronephric nephron tubule epithelial cell differentiation", "id": "GO:0035778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035778", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0S6S7", "url": "https://www.uniprot.org/uniprotkb/B0S6S7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QL21-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 3298, "chemical_mass": 357171.0, "gene_names": "dchs1b;dchs1b", "protein_name": "Protocadherin-16", "disease": [ { "disease_id": "DOID:0080585", "name": "Van Maldergem syndrome 1", "description": "A Van Maldergem syndrome that has_material_basis_in homozygous mutation in the DCHS1 gene on chromosome 11p15.", "url": "https://disease-ontology.org/term/DOID:0080585", "evidence": [ { "id": "0080585", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080585" } ], "weight": 0.0 }, { "disease_id": "DOID:988", "name": "mitral valve prolapse", "description": "A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.", "url": "https://disease-ontology.org/term/DOID:988", "evidence": [ { "id": "988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:988" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "atrioventricular canal development", "id": "GO:0036302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036302", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "tissue morphogenesis", "id": "GO:0048729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048729", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "mitotic cleavage furrow formation", "id": "GO:1903673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903673", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "mitral valve morphogenesis", "id": "GO:0003183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003183", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "microtubule polymerization or depolymerization", "id": "GO:0031109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031109", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "egg activation", "id": "GO:0007343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007343", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" }, { "name": "cortical granule exocytosis", "id": "GO:0060471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060471", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QL21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QL21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TDP2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDP2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDP2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 378, "chemical_mass": 42405.0, "gene_names": "ca9;ca9", "protein_name": "Carbonic anhydrase", "disease": [ { "disease_id": "DOID:0080365", "name": "endometrial hyperplasia", "description": "An uterine benign neoplasm that is characterized by excessive proliferation of the cells of the endometrium.", "url": "https://disease-ontology.org/term/DOID:0080365", "evidence": [ { "id": "0080365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080365" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDP2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDP2" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDP2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TFE0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TFE0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 367, "chemical_mass": 42510.0, "gene_names": "terf1;terf1", "protein_name": "Telomeric repeat-binding factor", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TFE0" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TFE0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TFE0" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TFE0" } ], "pmid": "" }, { "name": "double-stranded telomeric DNA binding", "id": "GO:0003691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003691", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TFE0" } ], "pmid": "" } ], "biological_process": [ { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TFE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B6RSP1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B6RSP1", "url": "https://www.uniprot.org/uniprotkb/B6RSP1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1197, "chemical_mass": 135554.0, "gene_names": "plekha7a;plekha7;hadp1;plekha7;si:dkey-29p10.1", "protein_name": "Pleckstrin homology domain-containing family A member 7", "disease": [ { "disease_id": "DOID:0050851", "name": "glomerulosclerosis", "description": "A glomerulonephritis that is characterized by hardening of the glomerulus in the kidney.", "url": "https://disease-ontology.org/term/DOID:0050851", "evidence": [ { "id": "0050851", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050851" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "B6RSP1", "url": "https://www.uniprot.org/uniprotkb/B6RSP1" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "B6RSP1", "url": "https://www.uniprot.org/uniprotkb/B6RSP1" } ], "pmid": "" } ], "molecular_function": [ { "name": "delta-catenin binding", "id": "GO:0070097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070097", "evidence": [ { "database": "UniProtKB", "id": "B6RSP1", "url": "https://www.uniprot.org/uniprotkb/B6RSP1" } ], "pmid": "" } ], "biological_process": [ { "name": "zonula adherens maintenance", "id": "GO:0045218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045218", "evidence": [ { "database": "UniProtKB", "id": "B6RSP1", "url": "https://www.uniprot.org/uniprotkb/B6RSP1" } ], "pmid": "" }, { "name": "epithelial cell-cell adhesion", "id": "GO:0090136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090136", "evidence": [ { "database": "UniProtKB", "id": "B6RSP1", "url": "https://www.uniprot.org/uniprotkb/B6RSP1" } ], "pmid": "" }, { "name": "regulation of heart contraction", "id": "GO:0008016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008016", "evidence": [ { "database": "UniProtKB", "id": "B6RSP1", "url": "https://www.uniprot.org/uniprotkb/B6RSP1" } ], "pmid": "" }, { "name": "cardiac muscle cell differentiation", "id": "GO:0055007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055007", "evidence": [ { "database": "UniProtKB", "id": "B6RSP1", "url": "https://www.uniprot.org/uniprotkb/B6RSP1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B6RSP1-1", "start_pos": "351", "end_pos": "351", "site_lbl": "Thr351", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 351, "start_aa": "Thr", "end_pos": 351, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr351", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QKH6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2053, "chemical_mass": 232172.0, "gene_names": "atrx;atrxl;atrx;wu:fb26e12;wu:fb52h08;wu:fb72g09;wu:fb94e07;zgc:66223", "protein_name": "DNA helicase", "disease": [ { "disease_id": "DOID:0080982", "name": "X-linked intellectual disability-hypotonic facies syndrome-1", "description": "A syndromic X-linked intellectual disability that is characterized primarily by severely impaired intellectual development, dysmorphic facies, and a highly skewed X-inactivation pattern in carrier women and that has_material_basis_in mutation in the ATRX gene on chromosome Xq13. This now comprises several syndromes previously reported separately, including Carpenter-Waziri syndrome, Holmes-Gang syndrome, and Smith-Fineman-Myers syndrome.", "url": "https://disease-ontology.org/term/DOID:0080982", "evidence": [ { "id": "0080982", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080982" } ], "weight": 0.0 }, { "disease_id": "DOID:0110030", "name": "alpha thalassemia-X-linked intellectual disability syndrome", "description": "An alpha thalassemia that has_material_basis_in mutation in the ATRX gene on Xq21.", "url": "https://disease-ontology.org/term/DOID:0110030", "evidence": [ { "id": "0110030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110030" } ], "weight": 0.0 }, { "disease_id": "DOID:0112125", "name": "alpha-thalassemia myelodysplasia syndrome", "description": "A syndrome characterized by acquired alpha-thalassemia in association with a multilineage myelodysplasia that has_material_basis_in somatic mutation in the ATRX gene on chromosome Xq21.1.", "url": "https://disease-ontology.org/term/DOID:0112125", "evidence": [ { "id": "0112125", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112125" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1115", "name": "sarcoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm.", "url": "https://disease-ontology.org/term/DOID:1115", "evidence": [ { "id": "1115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1115" } ], "weight": 0.0 }, { "disease_id": "DOID:1799", "name": "islet cell tumor", "description": "A pancreatic cancer that is located_in the pancreatic islet cells.", "url": "https://disease-ontology.org/term/DOID:1799", "evidence": [ { "id": "1799", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1799" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3069", "name": "malignant astrocytoma", "description": "A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord.", "url": "https://disease-ontology.org/term/DOID:3069", "evidence": [ { "id": "3069", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3069" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "constitutive heterochromatin formation", "id": "GO:0140719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140719", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BID7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1121, "chemical_mass": 126179.0, "gene_names": "prdm10;si:ch211-151h10.3;si:dkey-11k4.2", "protein_name": "PR domain zinc finger protein 10", "disease": [ { "disease_id": "DOID:0050676", "name": "Birt-Hogg-Dube syndrome", "description": "A skin disease that is characterized by hair follicle hamartomas, kidney tumors, and spontaneous pneumothorax, has_material_basis_in heterozygous mutation in the gene encoding folliculin (FLCN) on chromosome 17p11.", "url": "https://disease-ontology.org/term/DOID:0050676", "evidence": [ { "id": "0050676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050676" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A2BID7", "url": "https://www.uniprot.org/uniprotkb/A2BID7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8E534-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 406, "chemical_mass": 46752.0, "gene_names": "kdm8;jmjd5;zgc:173863;zgc:91962", "protein_name": "Lysine-specific demethylase 8", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "histone H3K36 demethylase activity", "id": "GO:0051864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051864", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "peptidyl-arginine 3-dioxygenase activity", "id": "GO:0106157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106157", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "histone H3K36me/H3K36me2 demethylase activity", "id": "GO:0140680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140680", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "protein destabilization", "id": "GO:0031648", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031648", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A8E534", "url": "https://www.uniprot.org/uniprotkb/A8E534" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R034-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R034", "url": "https://www.uniprot.org/uniprotkb/B0R034" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2067, "chemical_mass": 236124.0, "gene_names": "dock11;dock11;si:ch211-150g2.3", "protein_name": "Dedicator of cytokinesis protein 11", "disease": [], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "B0R034", "url": "https://www.uniprot.org/uniprotkb/B0R034" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "B0R034", "url": "https://www.uniprot.org/uniprotkb/B0R034" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "B0R034", "url": "https://www.uniprot.org/uniprotkb/B0R034" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "B0R034", "url": "https://www.uniprot.org/uniprotkb/B0R034" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0R034-1", "start_pos": "1391", "end_pos": "1391", "site_lbl": "Thr1391", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1391, "start_aa": "Thr", "end_pos": 1391, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1391", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BEA6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 570, "chemical_mass": 62395.0, "gene_names": "arid3a;arid3c;arid3a;arid3c;si:ch211-113n10.6", "protein_name": "AT-rich interactive domain-containing protein 3A", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2BEA6-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Ser179", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A2BEA6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BEA6" } ] } ] }, { "uniprot_canonical_ac": "A2BEA6-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Ser356", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A2BEA6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BEA6" } ] } ] }, { "uniprot_canonical_ac": "A2BEA6-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Ser542", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A2BEA6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BEA6" } ] } ] }, { "uniprot_canonical_ac": "A2BEA6-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Ser569", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A2BEA6", "url": "https://www.uniprot.org/uniprotkb/A2BEA6" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A2BEA6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2BEA6" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WUY6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 320, "chemical_mass": 35476.0, "gene_names": "stpg1;MAPO2;UPF0490;si:ch73-278j5.1;si:dkey-218f9.1", "protein_name": "O(6)-methylguanine-induced apoptosis 2", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" }, { "name": "female pronucleus", "id": "GO:0001939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001939", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" }, { "name": "male pronucleus", "id": "GO:0001940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001940", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" }, { "name": "germinal vesicle", "id": "GO:0042585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042585", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" }, { "name": "epigenetic programing of male pronucleus", "id": "GO:0044727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044727", "evidence": [ { "database": "UniProtKB", "id": "A5WUY6", "url": "https://www.uniprot.org/uniprotkb/A5WUY6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L1R6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1365, "chemical_mass": 151465.0, "gene_names": "znf423;si:ch211-212o1.3;si:ch211-216l23.1;wu:fc95d03;zgc:158272;znf423", "protein_name": "Zinc finger protein 423", "disease": [ { "disease_id": "DOID:0111122", "name": "nephronophthisis 14", "description": "A nephronophthisis that has_material_basis_in homozygous mutation in the ZNF423 gene on chromosome 16q12.1.", "url": "https://disease-ontology.org/term/DOID:0111122", "evidence": [ { "id": "0111122", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111122" } ], "weight": 0.0 }, { "disease_id": "DOID:2785", "name": "Dandy-Walker syndrome", "description": "A cerebellar disease that is characterized by hypoplasia and upward rotation of the cerebellar vermis and cystic dilation of the fourth ventricle.", "url": "https://disease-ontology.org/term/DOID:2785", "evidence": [ { "id": "2785", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2785" } ], "weight": 0.0 }, { "disease_id": "DOID:2786", "name": "cerebellar disease", "description": "A brain disease that is characterized by damage to brain substance located_in cerebellum; has_symptom ataxia, has_symptom dysarthria, and has_symptom cerebellar cognitive affective syndrome.", "url": "https://disease-ontology.org/term/DOID:2786", "evidence": [ { "id": "2786", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2786" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A1L1R6", "url": "https://www.uniprot.org/uniprotkb/A1L1R6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A7MC22-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A7MC22", "url": "https://www.uniprot.org/uniprotkb/A7MC22" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 314, "chemical_mass": 36498.0, "gene_names": "ccdc69", "protein_name": "Coiled-coil domain-containing protein 69", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A7MC22", "url": "https://www.uniprot.org/uniprotkb/A7MC22" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A7MC22", "url": "https://www.uniprot.org/uniprotkb/A7MC22" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A7MC22", "url": "https://www.uniprot.org/uniprotkb/A7MC22" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A7MC22", "url": "https://www.uniprot.org/uniprotkb/A7MC22" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A7MC22", "url": "https://www.uniprot.org/uniprotkb/A7MC22" } ], "pmid": "" } ], "biological_process": [ { "name": "spindle midzone assembly", "id": "GO:0051255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051255", "evidence": [ { "database": "UniProtKB", "id": "A7MC22", "url": "https://www.uniprot.org/uniprotkb/A7MC22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0S6R1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1128, "chemical_mass": 128741.0, "gene_names": "nckap1;nckap1;si:dkey-234n3.1;wu:fd05c01", "protein_name": "Nck-associated protein 1", "disease": [ { "disease_id": "DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.", "url": "https://disease-ontology.org/term/DOID:0060037", "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ], "weight": 0.0 } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "pmid": "" } ], "cellular_component": [ { "name": "SCAR complex", "id": "GO:0031209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031209", "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "pmid": "" }, { "name": "lamellipodium membrane", "id": "GO:0031258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031258", "evidence": [ { "database": "UniProtKB", "id": "B0S6R1", "url": "https://www.uniprot.org/uniprotkb/B0S6R1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CE83-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 311, "chemical_mass": 35359.0, "gene_names": "entr1;sdccag3;si:dkey-1o2.3", "protein_name": "Endosome-associated-trafficking regulator 1", "disease": [], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cilium", "id": "GO:1903566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903566", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A2CE83", "url": "https://www.uniprot.org/uniprotkb/A2CE83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BGL0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGL0", "url": "https://www.uniprot.org/uniprotkb/A2BGL0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 744, "chemical_mass": 83042.0, "gene_names": "papolg;papolg;zgc:63762", "protein_name": "polynucleotide adenylyltransferase", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A2BGL0", "url": "https://www.uniprot.org/uniprotkb/A2BGL0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2BGL0", "url": "https://www.uniprot.org/uniprotkb/A2BGL0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A2BGL0", "url": "https://www.uniprot.org/uniprotkb/A2BGL0" } ], "pmid": "" }, { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "A2BGL0", "url": "https://www.uniprot.org/uniprotkb/A2BGL0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BGL0", "url": "https://www.uniprot.org/uniprotkb/A2BGL0" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A2BGL0", "url": "https://www.uniprot.org/uniprotkb/A2BGL0" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "A2BGL0", "url": "https://www.uniprot.org/uniprotkb/A2BGL0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2BGL0-1", "start_pos": "612", "end_pos": "612", "site_lbl": "Thr612", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 612, "start_aa": "Thr", "end_pos": 612, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr612", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L1G1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 714, "chemical_mass": 78136.0, "gene_names": "esrp1;esrp1;rbm35a;wu:fi28a07;zgc:154050", "protein_name": "Epithelial splicing regulatory protein 1", "disease": [ { "disease_id": "DOID:0111639", "name": "autosomal recessive nonsyndromic deafness 109", "description": "An autosomal recessive nonsyndromic deafness characterized by bilateral congenital severe to profound sensorineural hearing loss and vestibular dysplasia without balance or movement issues that has_material_basis_in homozygous or compound heterozygous mutation in the ESRP1 gene on chromosome 8q22.1.", "url": "https://disease-ontology.org/term/DOID:0111639", "evidence": [ { "id": "0111639", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111639" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" }, { "name": "hard palate morphogenesis", "id": "GO:1905748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905748", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A1L1G1", "url": "https://www.uniprot.org/uniprotkb/A1L1G1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMD2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMD2", "url": "https://www.uniprot.org/uniprotkb/A0JMD2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 969, "chemical_mass": 106964.0, "gene_names": "zfyve28;id:ibd1374;lst2;zfyve28;zgc:152894", "protein_name": "Lateral signaling target protein 2 homolog", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0JMD2", "url": "https://www.uniprot.org/uniprotkb/A0JMD2" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0JMD2", "url": "https://www.uniprot.org/uniprotkb/A0JMD2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0JMD2", "url": "https://www.uniprot.org/uniprotkb/A0JMD2" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0JMD2", "url": "https://www.uniprot.org/uniprotkb/A0JMD2" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042059", "evidence": [ { "database": "UniProtKB", "id": "A0JMD2", "url": "https://www.uniprot.org/uniprotkb/A0JMD2" } ], "pmid": "" }, { "name": "negative regulation of epidermal growth factor-activated receptor activity", "id": "GO:0007175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007175", "evidence": [ { "database": "UniProtKB", "id": "A0JMD2", "url": "https://www.uniprot.org/uniprotkb/A0JMD2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JME2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 815, "chemical_mass": 85267.0, "gene_names": "atf7ip;atf7ip;fa12g02;mcaf1;si:dkey-48a12.2;wu:fa12g02;zgc:152981", "protein_name": "Activating transcription factor 7-interacting protein 1", "disease": [ { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0JME2-1", "start_pos": "404", "end_pos": "404", "site_lbl": "Thr404", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0JME2-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Ser125", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A0JME2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A0JME2" } ] } ] }, { "uniprot_canonical_ac": "A0JME2-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Ser127", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A0JME2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A0JME2" } ] } ] }, { "uniprot_canonical_ac": "A0JME2-1", "start_pos": "344", "end_pos": "344", "site_lbl": "Thr344", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A0JME2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A0JME2" } ] } ] }, { "uniprot_canonical_ac": "A0JME2-1", "start_pos": "628", "end_pos": "628", "site_lbl": "Ser628", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0JME2", "url": "https://www.uniprot.org/uniprotkb/A0JME2" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A0JME2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A0JME2" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1A5X5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1A5X5", "url": "https://www.uniprot.org/uniprotkb/A1A5X5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 318, "chemical_mass": 34826.0, "gene_names": "c1qtnf12;c1qdc2;c1qtnf12;fam132a;zgc:158358", "protein_name": "Adipolin", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1A5X5", "url": "https://www.uniprot.org/uniprotkb/A1A5X5" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1A5X5", "url": "https://www.uniprot.org/uniprotkb/A1A5X5" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of D-glucose import", "id": "GO:0046324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046324", "evidence": [ { "database": "UniProtKB", "id": "A1A5X5", "url": "https://www.uniprot.org/uniprotkb/A1A5X5" } ], "pmid": "" } ], "molecular_function": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A1A5X5", "url": "https://www.uniprot.org/uniprotkb/A1A5X5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1A5X5-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Asn44", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 44, "start_aa": "Asn", "end_pos": 44, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn44", "evidence": [ { "id": "A1A5X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5X5#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A6H8T2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A6H8T2", "url": "https://www.uniprot.org/uniprotkb/A6H8T2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 731, "chemical_mass": 84222.0, "gene_names": "dnai7;casc1;cfap94;si:dkey-172o10.5", "protein_name": "Dynein axonemal intermediate chain 7", "disease": [], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A6H8T2", "url": "https://www.uniprot.org/uniprotkb/A6H8T2" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A6H8T2", "url": "https://www.uniprot.org/uniprotkb/A6H8T2" } ], "pmid": "" } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A6H8T2", "url": "https://www.uniprot.org/uniprotkb/A6H8T2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R0W9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R0W9", "url": "https://www.uniprot.org/uniprotkb/B0R0W9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1108, "chemical_mass": 126737.0, "gene_names": "tbc1d8b;fc28a09;si:dkey-110k5.6;tbc1d8b;wu:fc28a09", "protein_name": "TBC1 domain family member 8B", "disease": [ { "disease_id": "DOID:0070357", "name": "nephrotic syndrome type 20", "description": "A familial nephrotic syndrome that has_material_basis_in X-linked renal disorder characterized by onset of steroid-resistant nephrotic syndrome and proteinuria in the first years of life in affected males.", "url": "https://disease-ontology.org/term/DOID:0070357", "evidence": [ { "id": "0070357", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070357" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "B0R0W9", "url": "https://www.uniprot.org/uniprotkb/B0R0W9" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "B0R0W9", "url": "https://www.uniprot.org/uniprotkb/B0R0W9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B0R0W9", "url": "https://www.uniprot.org/uniprotkb/B0R0W9" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "B0R0W9", "url": "https://www.uniprot.org/uniprotkb/B0R0W9" } ], "pmid": "" }, { "name": "glomerular filtration", "id": "GO:0003094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003094", "evidence": [ { "database": "UniProtKB", "id": "B0R0W9", "url": "https://www.uniprot.org/uniprotkb/B0R0W9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B3DGU2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 502, "chemical_mass": 57908.0, "gene_names": "rab11fip4b;rab11fip4b;zgc:193668", "protein_name": "Rab11 family-interacting protein 4B", "disease": [], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "B3DGU2", "url": "https://www.uniprot.org/uniprotkb/B3DGU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0UXI4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 670, "chemical_mass": 72354.0, "gene_names": "syn1;si:dkey-90n12.3;syn1", "protein_name": "Synapsin-1", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0112029", "name": "non-syndromic X-linked intellectual disability 50", "description": "A non-syndromic X-linked intellectual disability characterized by moderate intellectual disability that has_material_basis_in mutation in a region on chromosome Xp11.3-p11.21.", "url": "https://disease-ontology.org/term/DOID:0112029", "evidence": [ { "id": "0112029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112029" } ], "weight": 0.0 }, { "disease_id": "DOID:0112122", "name": "X-linked epilepsy with variable learning disabilities and behavior disorders", "description": "An epilepsy characterized by epilepsy with variable learning disabilities and behavioral disorders in some patients that has_material_basis_in heterozygous or hemizygous mutation in the SYN1 gene on chromosome Xp11.3-p11.2.", "url": "https://disease-ontology.org/term/DOID:0112122", "evidence": [ { "id": "0112122", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112122" } ], "weight": 0.0 }, { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "pmid": "" } ], "biological_process": [ { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "pmid": "" }, { "name": "synaptic vesicle clustering", "id": "GO:0097091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097091", "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "B0UXI4", "url": "https://www.uniprot.org/uniprotkb/B0UXI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IGC3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 195, "chemical_mass": 22412.0, "gene_names": "rilpl2;fa02e07;rilpl2;si:ch211-275j6.7;wu:fa02e07;zgc:162589", "protein_name": "RILP-like protein 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "epithelial cell morphogenesis", "id": "GO:0003382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003382", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "protein transport from ciliary membrane to plasma membrane", "id": "GO:1903445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903445", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A4IGC3", "url": "https://www.uniprot.org/uniprotkb/A4IGC3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WUN7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1558, "chemical_mass": 173900.0, "gene_names": "camsap1b;camsap1;si:dkey-157g20.3", "protein_name": "Calmodulin-regulated spectrin-associated protein 1-B", "disease": [ { "disease_id": "DOID:0061141", "name": "complex cortical dysplasia with other brain malformations 12", "description": "A complex cortical dysplasia with other brain malformations characterized by severe to profound neurodevelopmental delay with absent speech, central hypotonia, peripheral spasticity, cortical visual impairment, and dysmorphic craniofacial features that has_material_basis_in homozygous or compound heterozygous mutations in the CAMSAP1 gene on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:0061141", "evidence": [ { "id": "0061141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061141" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" }, { "name": "microtubule minus-end binding", "id": "GO:0051011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051011", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" }, { "name": "regulation of microtubule polymerization", "id": "GO:0031113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031113", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A5WUN7", "url": "https://www.uniprot.org/uniprotkb/A5WUN7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5WUN7-1", "start_pos": "1086", "end_pos": "1086", "site_lbl": "Thr1086", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1086, "start_aa": "Thr", "end_pos": 1086, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1086", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A5WUN7-1", "start_pos": "567", "end_pos": "567", "site_lbl": "Thr567", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 567, "start_aa": "Thr", "end_pos": 567, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr567", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4FUM1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 423, "chemical_mass": 49099.0, "gene_names": "sept8b;septin8b;Septin-8-B;sept8b;septin8b;zgc:136574", "protein_name": "Septin-8-B", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" } ], "cellular_component": [ { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A4FUM1", "url": "https://www.uniprot.org/uniprotkb/A4FUM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WV69-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WV69", "url": "https://www.uniprot.org/uniprotkb/A5WV69" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 410, "chemical_mass": 45788.0, "gene_names": "acbd5b;acbd5b;si:ch211-112d19.6", "protein_name": "Acyl-CoA-binding domain-containing protein 5-B", "disease": [ { "disease_id": "DOID:0080946", "name": "retinal dystrophy with leukodystrophy", "description": "A peroxisomal disease that is characterized by a peroxisomal enzyme deficiency caused by impaired very long chain fatty acid (VLCFA) metabolism and that has_material_basis_in homozygous mutation in the ACBD5 gene on chromosome 10p12.", "url": "https://disease-ontology.org/term/DOID:0080946", "evidence": [ { "id": "0080946", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080946" } ], "weight": 0.0 }, { "disease_id": "DOID:906", "name": "peroxisomal disease", "description": "An inherited metabolic disorder that involves peroxisome malfunction.", "url": "https://disease-ontology.org/term/DOID:906", "evidence": [ { "id": "906", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:906" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5WV69", "url": "https://www.uniprot.org/uniprotkb/A5WV69" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A5WV69", "url": "https://www.uniprot.org/uniprotkb/A5WV69" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5WV69", "url": "https://www.uniprot.org/uniprotkb/A5WV69" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A5WV69", "url": "https://www.uniprot.org/uniprotkb/A5WV69" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "A5WV69", "url": "https://www.uniprot.org/uniprotkb/A5WV69" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "A5WV69", "url": "https://www.uniprot.org/uniprotkb/A5WV69" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IG66-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IG66", "url": "https://www.uniprot.org/uniprotkb/A4IG66" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 651, "chemical_mass": 72016.0, "gene_names": "tmem201;tmem201;zgc:162289", "protein_name": "Transmembrane protein 201", "disease": [], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A4IG66", "url": "https://www.uniprot.org/uniprotkb/A4IG66" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell migration", "id": "GO:0010595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010595", "evidence": [ { "database": "UniProtKB", "id": "A4IG66", "url": "https://www.uniprot.org/uniprotkb/A4IG66" } ], "pmid": "" }, { "name": "nuclear migration along microtubule", "id": "GO:0030473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030473", "evidence": [ { "database": "UniProtKB", "id": "A4IG66", "url": "https://www.uniprot.org/uniprotkb/A4IG66" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A4IG66", "url": "https://www.uniprot.org/uniprotkb/A4IG66" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A4IG66", "url": "https://www.uniprot.org/uniprotkb/A4IG66" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A4IG66", "url": "https://www.uniprot.org/uniprotkb/A4IG66" } ], "pmid": "" }, { "name": "lamin binding", "id": "GO:0005521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005521", "evidence": [ { "database": "UniProtKB", "id": "A4IG66", "url": "https://www.uniprot.org/uniprotkb/A4IG66" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A4IG66-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Asn124", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 124, "start_aa": "Asn", "end_pos": 124, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn124", "evidence": [ { "id": "A4IG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IG66#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4IG66-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Asn259", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 259, "start_aa": "Asn", "end_pos": 259, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn259", "evidence": [ { "id": "A4IG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IG66#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4IG66-1", "start_pos": "421", "end_pos": "421", "site_lbl": "Asn421", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 421, "start_aa": "Asn", "end_pos": 421, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn421", "evidence": [ { "id": "A4IG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IG66#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4IG66-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Thr501", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 501, "start_aa": "Thr", "end_pos": 501, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr501", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A4IG66-1", "start_pos": "528", "end_pos": "528", "site_lbl": "Asn528", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 528, "start_aa": "Asn", "end_pos": 528, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn528", "evidence": [ { "id": "A4IG66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IG66#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CEA7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEA7", "url": "https://www.uniprot.org/uniprotkb/A2CEA7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1244, "chemical_mass": 141587.0, "gene_names": "rasgrf2b;rasgrf2;rasgrf2-2;rasgrf2b;rasgrf2;si:ch211-194b21.1;si:dkey-56d12.3", "protein_name": "Ras-specific guanine nucleotide-releasing factor 2", "disease": [], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A2CEA7", "url": "https://www.uniprot.org/uniprotkb/A2CEA7" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A2CEA7", "url": "https://www.uniprot.org/uniprotkb/A2CEA7" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2CEA7", "url": "https://www.uniprot.org/uniprotkb/A2CEA7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A2CEA7", "url": "https://www.uniprot.org/uniprotkb/A2CEA7" } ], "pmid": "" } ], "biological_process": [ { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A2CEA7", "url": "https://www.uniprot.org/uniprotkb/A2CEA7" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A2CEA7", "url": "https://www.uniprot.org/uniprotkb/A2CEA7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CEQ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 469, "chemical_mass": 52712.0, "gene_names": "slc25a25b;scamc2b;si:dkey-7o20.1;slc25a25b", "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A25-B", "disease": [], "biological_process": [ { "name": "left/right pattern formation", "id": "GO:0060972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060972", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" }, { "name": "ADP transport", "id": "GO:0015866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015866", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" }, { "name": "ATP transport", "id": "GO:0015867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015867", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" }, { "name": "ATP transmembrane transporter activity", "id": "GO:0005347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005347", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A2CEQ0", "url": "https://www.uniprot.org/uniprotkb/A2CEQ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0V207-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V207", "url": "https://www.uniprot.org/uniprotkb/B0V207" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1124, "chemical_mass": 123015.0, "gene_names": "fhip1b;FHIP;fam160a2;fhip1b;si:ch211-39h10.1", "protein_name": "FHF complex subunit HOOK-interacting protein 1B", "disease": [], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "B0V207", "url": "https://www.uniprot.org/uniprotkb/B0V207" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "B0V207", "url": "https://www.uniprot.org/uniprotkb/B0V207" } ], "pmid": "" }, { "name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "B0V207", "url": "https://www.uniprot.org/uniprotkb/B0V207" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "B0V207", "url": "https://www.uniprot.org/uniprotkb/B0V207" } ], "pmid": "" }, { "name": "early endosome to late endosome transport", "id": "GO:0045022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022", "evidence": [ { "database": "UniProtKB", "id": "B0V207", "url": "https://www.uniprot.org/uniprotkb/B0V207" } ], "pmid": "" }, { "name": "protein localization to perinuclear region of cytoplasm", "id": "GO:1905719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905719", "evidence": [ { "database": "UniProtKB", "id": "B0V207", "url": "https://www.uniprot.org/uniprotkb/B0V207" } ], "pmid": "" } ], "cellular_component": [ { "name": "FHF complex", "id": "GO:0070695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070695", "evidence": [ { "database": "UniProtKB", "id": "B0V207", "url": "https://www.uniprot.org/uniprotkb/B0V207" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0V207-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Thr492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 492, "start_aa": "Thr", "end_pos": 492, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr492", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A7UA95-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A7UA95", "url": "https://www.uniprot.org/uniprotkb/A7UA95" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1124, "chemical_mass": 124934.0, "gene_names": "radil;radil", "protein_name": "Ras-associating and dilute domain-containing protein", "disease": [], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A7UA95", "url": "https://www.uniprot.org/uniprotkb/A7UA95" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A7UA95", "url": "https://www.uniprot.org/uniprotkb/A7UA95" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A7UA95", "url": "https://www.uniprot.org/uniprotkb/A7UA95" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A7UA95", "url": "https://www.uniprot.org/uniprotkb/A7UA95" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A7UA95", "url": "https://www.uniprot.org/uniprotkb/A7UA95" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A7UA95", "url": "https://www.uniprot.org/uniprotkb/A7UA95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L243-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L243", "url": "https://www.uniprot.org/uniprotkb/A1L243" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 206, "chemical_mass": 23307.0, "gene_names": "mesd;mesdc2;mesd;zgc:158636", "protein_name": "LRP chaperone MESD", "disease": [ { "disease_id": "DOID:0111849", "name": "osteogenesis imperfecta type 20", "description": "An osteogenesis imperfecta characterized by osteopenia, skeletal deformity, and both healed and new fractures on radiography that has_material_basis_in homozygous or compound heterozygous mutation in MESD on chromosome 15q25.1.", "url": "https://disease-ontology.org/term/DOID:0111849", "evidence": [ { "id": "0111849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111849" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of skeletal muscle acetylcholine-gated channel clustering", "id": "GO:1904395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904395", "evidence": [ { "database": "UniProtKB", "id": "A1L243", "url": "https://www.uniprot.org/uniprotkb/A1L243" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A1L243", "url": "https://www.uniprot.org/uniprotkb/A1L243" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A1L243", "url": "https://www.uniprot.org/uniprotkb/A1L243" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A1L243", "url": "https://www.uniprot.org/uniprotkb/A1L243" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMF8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 765, "chemical_mass": 84548.0, "gene_names": "rfx3;rfx3;zgc:153245", "protein_name": "Transcription factor RFX3", "disease": [ { "disease_id": "DOID:0050545", "name": "visceral heterotaxy", "description": "A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.", "url": "https://disease-ontology.org/term/DOID:0050545", "evidence": [ { "id": "0050545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050545" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "endocrine pancreas development", "id": "GO:0031018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031018", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "cilium-dependent cell motility", "id": "GO:0060285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060285", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "epithelial cilium movement involved in determination of left/right asymmetry", "id": "GO:0060287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060287", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0JMF8", "url": "https://www.uniprot.org/uniprotkb/A0JMF8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QDW0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 555, "chemical_mass": 63598.0, "gene_names": "kat5b;htatip;im:6908768;kat5b;wu:fb55b08;zgc:110752", "protein_name": "Histone acetyltransferase KAT5", "disease": [ { "disease_id": "DOID:11758", "name": "iron deficiency anemia", "description": "A microcytic anemia that is characterized by pallor, fatigue, lightheadedness, and weakness and has_material_basis_in low total body iron causing impaired synthesis of red blood cells.", "url": "https://disease-ontology.org/term/DOID:11758", "evidence": [ { "id": "11758", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11758" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "histone H4K16 acetyltransferase activity", "id": "GO:0046972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046972", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "cellular response to oxygen-containing compound", "id": "GO:1901701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901701", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QDW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B2ZGJ1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B2ZGJ1", "url": "https://www.uniprot.org/uniprotkb/B2ZGJ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 637, "chemical_mass": 71840.0, "gene_names": "chata;chat;chata;chat;unm_tk64", "protein_name": "Choline O-acetyltransferase", "disease": [ { "disease_id": "DOID:0110671", "name": "congenital myasthenic syndrome 6", "description": "A congenital myasthenic syndrome characterized by autosomal recessive inheritance of a presynaptic defect resulting in onset of muscle weakeness in infancy or early childhood and a tendency to have sudden apneic episodes that has_material_basis_in homozygous or compound heterozygous mutation in the CHAT gene on chromosome 10q.", "url": "https://disease-ontology.org/term/DOID:0110671", "evidence": [ { "id": "0110671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110671" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3635", "name": "congenital myasthenic syndrome", "description": "A neuromuscular junction disease that is characterized by weakness and easy fatiguability resulting from a genetic defect at the junction where the nerve stimulates muscle activity that result in muscle weakness and may affect nerve cells (presynaptic), muscle cells (postsynaptic) or the space between nerve and muscle cells (synaptic).", "url": "https://disease-ontology.org/term/DOID:3635", "evidence": [ { "id": "3635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3635" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "choline O-acetyltransferase activity", "id": "GO:0004102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004102", "evidence": [ { "database": "UniProtKB", "id": "B2ZGJ1", "url": "https://www.uniprot.org/uniprotkb/B2ZGJ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B2ZGJ1", "url": "https://www.uniprot.org/uniprotkb/B2ZGJ1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "B2ZGJ1", "url": "https://www.uniprot.org/uniprotkb/B2ZGJ1" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "B2ZGJ1", "url": "https://www.uniprot.org/uniprotkb/B2ZGJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "B2ZGJ1", "url": "https://www.uniprot.org/uniprotkb/B2ZGJ1" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "B2ZGJ1", "url": "https://www.uniprot.org/uniprotkb/B2ZGJ1" } ], "pmid": "" }, { "name": "acetylcholine biosynthetic process", "id": "GO:0008292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008292", "evidence": [ { "database": "UniProtKB", "id": "B2ZGJ1", "url": "https://www.uniprot.org/uniprotkb/B2ZGJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QEC7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEC7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEC7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 406, "chemical_mass": 47144.0, "gene_names": "st6galnac1.1;si:ch211-51n14.1;siat3;st6GalNAc I;st6galnac1.1", "protein_name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEC7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEC7" } ], "pmid": "" } ], "biological_process": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEC7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEC7" } ], "pmid": "" }, { "name": "oligosaccharide biosynthetic process", "id": "GO:0009312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009312", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEC7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEC7" } ], "pmid": "" }, { "name": "host-mediated modulation of intestinal microbiota composition", "id": "GO:0048874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048874", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEC7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEC7" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity", "id": "GO:0001665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001665", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEC7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QEH5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEH5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 574, "chemical_mass": 65495.0, "gene_names": "srrm4;ZnSR100;im:7136231;nSR100;si:dkey-1k23.1;srrm4", "protein_name": "", "disease": [], "biological_process": [ { "name": "facial nucleus development", "id": "GO:0021754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021754", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEH5" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEH5" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEH5" } ], "pmid": "" }, { "name": "neuron maturation", "id": "GO:0042551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042551", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEH5" } ], "pmid": "" } ], "cellular_component": [ { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QEH5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEH5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QF71-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QF71", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QF71" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 225, "chemical_mass": 25508.0, "gene_names": "cacng1a;cacng1a;cacng1;wu:fb43f02;wu:fi19g08;zgc:55364", "protein_name": "Voltage-dependent calcium channel gamma-1 subunit", "disease": [ { "disease_id": "DOID:8545", "name": "malignant hyperthermia", "description": "A muscle tissue disease that is characterized by a drastic and uncontrolled increase in skeletal muscle oxidative metabolism, which overwhelms the body's capacity to supply oxygen, remove carbon dioxide, and regulate body temperature and that has_material_basis_in heterozygous mutation in the ryanodine receptor gene (RYR1) on chromosome 19q13. Manifestations of malignant hyperthermia (MH) are precipitated by certain volatile anesthetics (i.e., halothane, isoflurane, sevoflurane, desflurane, enflurane), either alone or in conjunction with a depolarizing muscle relaxant (specifically, succinylcholine).", "url": "https://disease-ontology.org/term/DOID:8545", "evidence": [ { "id": "8545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8545" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QF71", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QF71" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QF71", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QF71" } ], "pmid": "" } ], "molecular_function": [ { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QF71", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QF71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QG47-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG47", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG47" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 229, "chemical_mass": 25872.0, "gene_names": "adtrp;LOC100537455", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG47", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG47" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QG47", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QGK2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 414, "chemical_mass": 47283.0, "gene_names": "tgfb5;tgfb5", "protein_name": "Transforming growth factor beta", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" }, { "name": "positive regulation of cell division", "id": "GO:0051781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051781", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor binding", "id": "GO:0005160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005160", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QGK2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QGK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KPJ4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KPJ4", "url": "https://www.uniprot.org/uniprotkb/A3KPJ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1027, "chemical_mass": 115091.0, "gene_names": "ptprn2;IA-2[b];fc52a08;im:7153814;ptprn2;wu:fc52a08", "protein_name": "", "disease": [ { "disease_id": "DOID:11716", "name": "prediabetes syndrome", "description": "A glucose metabolism disease that is characterized by blood glucose levels are high, but not high enough to be classified as type 2 diabetes.", "url": "https://disease-ontology.org/term/DOID:11716", "evidence": [ { "id": "11716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11716" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A3KPJ4", "url": "https://www.uniprot.org/uniprotkb/A3KPJ4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A3KPJ4", "url": "https://www.uniprot.org/uniprotkb/A3KPJ4" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "A3KPJ4", "url": "https://www.uniprot.org/uniprotkb/A3KPJ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A3KPJ4", "url": "https://www.uniprot.org/uniprotkb/A3KPJ4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of secretion", "id": "GO:0051046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051046", "evidence": [ { "database": "UniProtKB", "id": "A3KPJ4", "url": "https://www.uniprot.org/uniprotkb/A3KPJ4" } ], "pmid": "" }, { "name": "insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0035773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035773", "evidence": [ { "database": "UniProtKB", "id": "A3KPJ4", "url": "https://www.uniprot.org/uniprotkb/A3KPJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QLM6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 345, "chemical_mass": 39477.0, "gene_names": "lims1;lims1;wu:fc32c03;zgc:112533", "protein_name": "LIM domain-containing protein", "disease": [], "biological_process": [ { "name": "regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051896", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "positive regulation of signal transduction", "id": "GO:0009967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009967", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "positive regulation of integrin-mediated signaling pathway", "id": "GO:2001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001046", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "cell-cell junction organization", "id": "GO:0045216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045216", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "intercalated disc", "id": "GO:0014704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014704", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLM6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLM6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QIG6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIG6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 646, "chemical_mass": 70922.0, "gene_names": "si:dkey-222h21.12;si:dkey-222h21.12", "protein_name": "Glutathione hydrolase", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0111257", "name": "gamma-glutamyl transpeptidase deficiency", "description": "An amino acid metabolic disorder characterized by accumulation of glutathione in the plasma and urine that has_material_basis_in homozygous or compound heterozygous mutation in GGT1 on 22q11.23.", "url": "https://disease-ontology.org/term/DOID:0111257", "evidence": [ { "id": "0111257", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111257" } ], "weight": 0.0 }, { "disease_id": "DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy.", "url": "https://disease-ontology.org/term/DOID:11714", "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ], "weight": 0.0 }, { "disease_id": "DOID:13608", "name": "biliary atresia", "description": "A cholestasis characterized by blockage of the ducts that carry bile from the liver to the gallbladder.", "url": "https://disease-ontology.org/term/DOID:13608", "evidence": [ { "id": "13608", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13608" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:5022", "name": "aflatoxins-related hepatocellular carcinoma", "description": "", "url": "https://disease-ontology.org/term/DOID:5022", "evidence": [ { "id": "5022", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5022" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glutathione catabolic process", "id": "GO:0006751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006751", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIG6" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIG6" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIG6" } ], "pmid": "" }, { "name": "peptide modification", "id": "GO:0031179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031179", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIG6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIG6" } ], "pmid": "" } ], "molecular_function": [ { "name": "glutathione hydrolase activity", "id": "GO:0036374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036374", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIG6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0UXY9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 675, "chemical_mass": 75554.0, "gene_names": "faf1;faf1;fc25h12;wu:fc25h12;zgc:55752", "protein_name": "", "disease": [], "biological_process": [ { "name": "pharyngeal system development", "id": "GO:0060037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060037", "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "pmid": "" }, { "name": "fin regeneration", "id": "GO:0031101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031101", "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "pmid": "" } ], "molecular_function": [ { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "B0UXY9", "url": "https://www.uniprot.org/uniprotkb/B0UXY9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0UXY9-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 80, "start_aa": "Thr", "end_pos": 80, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr80", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QIR2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 649, "chemical_mass": 73128.0, "gene_names": "parp2;adprtl2;cb996;parp2", "protein_name": "Poly [ADP-ribose] polymerase", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "NAD+-protein-aspartate ADP-ribosyltransferase activity", "id": "GO:0140806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140806", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "NAD+-protein-glutamate ADP-ribosyltransferase activity", "id": "GO:0140807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140807", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" } ], "biological_process": [ { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QIR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QMM1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 501, "chemical_mass": 55867.0, "gene_names": "map2k4b;MKK4B;map2k4b;zgc:194486", "protein_name": "mitogen-activated protein kinase kinase", "disease": [ { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:0050933", "name": "ovarian serous carcinoma", "description": "An ovarian carcinoma that has_material_basis_in the lining of the ovary and produces a serum-like fluid.", "url": "https://disease-ontology.org/term/DOID:0050933", "evidence": [ { "id": "0050933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050933" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2876", "name": "laryngeal squamous cell carcinoma", "description": "A laryngeal carcinoma that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:2876", "evidence": [ { "id": "2876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2876" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3717", "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8634", "name": "prostate carcinoma in situ", "description": "An in situ carcinoma that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:8634", "evidence": [ { "id": "8634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8634" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "pmid": "" }, { "name": "MAP kinase kinase activity", "id": "GO:0004708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004708", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to stress", "id": "GO:0033554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033554", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "pmid": "" }, { "name": "convergent extension involved in gastrulation", "id": "GO:0060027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060027", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "pmid": "" }, { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMM1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QMX0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 4007, "chemical_mass": 443678.0, "gene_names": "pkd1b;pkd1b", "protein_name": "", "disease": [ { "disease_id": "DOID:0110858", "name": "polycystic kidney disease 1", "description": "A autosomal dominant polycystic kidney disease that has_material_basis_in autosomal dominant inheritance of mutation in the PKD1 gene on chromosome 16p13.3.", "url": "https://disease-ontology.org/term/DOID:0110858", "evidence": [ { "id": "0110858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110858" } ], "weight": 0.0 }, { "disease_id": "DOID:0110861", "name": "autosomal recessive polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion.", "url": "https://disease-ontology.org/term/DOID:0110861", "evidence": [ { "id": "0110861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110861" } ], "weight": 0.0 }, { "disease_id": "DOID:10941", "name": "intracranial aneurysm", "description": "", "url": "https://disease-ontology.org/term/DOID:10941", "evidence": [ { "id": "10941", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10941" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:898", "name": "autosomal dominant polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion.", "url": "https://disease-ontology.org/term/DOID:898", "evidence": [ { "id": "898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:898" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMX0" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMX0" } ], "pmid": "" } ], "biological_process": [ { "name": "lymphangiogenesis", "id": "GO:0001946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001946", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMX0" } ], "pmid": "" }, { "name": "regulation of collagen biosynthetic process", "id": "GO:0032965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032965", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMX0" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMX0" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transport", "id": "GO:0098655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098655", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QMX0-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Thr293", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 293, "start_aa": "Thr", "end_pos": 293, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr293", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8M9QMX0-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Thr408", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 408, "start_aa": "Thr", "end_pos": 408, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr408", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QJN0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1954, "chemical_mass": 222257.0, "gene_names": "gng2;LOC137487211;zgc:110302", "protein_name": "ribonuclease H", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" }, { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" }, { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" } ], "biological_process": [ { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QJN0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QJN0-1", "start_pos": "997", "end_pos": "997", "site_lbl": "Thr997", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 997, "start_aa": "Thr", "end_pos": 997, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr997", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3FEM2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 235, "chemical_mass": 26343.0, "gene_names": "fev;fev;pet1;zgc:158720", "protein_name": "Protein FEV", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" }, { "name": "hematopoietic stem cell differentiation", "id": "GO:0060218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" }, { "name": "endothelium development", "id": "GO:0003158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003158", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A3FEM2", "url": "https://www.uniprot.org/uniprotkb/A3FEM2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QLA0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 467, "chemical_mass": 53112.0, "gene_names": "LOC101883213;LOC101883213", "protein_name": "Collagenase 3", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLA0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLA0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLA0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLA0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLA0" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLA0" } ], "pmid": "" }, { "name": "collagen catabolic process", "id": "GO:0030574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030574", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QLA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLA0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QMA5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2489, "chemical_mass": 276836.0, "gene_names": "apc2;apc2", "protein_name": "Adenomatous polyposis coli protein 2", "disease": [ { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0061143", "name": "complex cortical dysplasia with other brain malformations 10", "description": "A complex cortical dysplasia with other brain malformations characterized by severely impaired global development associated with abnormalities on brain imaging, including lissencephaly, cortical dysplasia, subcortical heterotopia, and paucity of white matter that has_material_basis_in homozygous or compound heterozygous mutation in the APC2 gene on chromosome 19p13.", "url": "https://disease-ontology.org/term/DOID:0061143", "evidence": [ { "id": "0061143", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061143" } ], "weight": 0.0 }, { "disease_id": "DOID:0080409", "name": "familial adenomatous polyposis 1", "description": "A familial adenomatous polyposis that is characterized by predisposition to cancer and that has_material_basis_in heterozygous mutation in the APC gene on chromosome 5q22. Affected individuals usually develop hundreds to thousands of adenomatous polyps of the colon and rectum, a small proportion of which will progress to colorectal carcinoma if not surgically treated.", "url": "https://disease-ontology.org/term/DOID:0080409", "evidence": [ { "id": "0080409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080409" } ], "weight": 0.0 }, { "disease_id": "DOID:0081218", "name": "autosomal recessive intellectual developmental disorder 74", "description": "An autosomal recessive intellectual developmental disorder that is characterized by intellectual impairment, macrocephaly, and dysmorphic features and that has_material_basis_in homozygous mutation in the APC2 gene on chromosome 19p13. Epilepsy with eyelid myoclonus has also been reported.", "url": "https://disease-ontology.org/term/DOID:0081218", "evidence": [ { "id": "0081218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081218" } ], "weight": 0.0 }, { "disease_id": "DOID:0112104", "name": "Sotos syndrome 3", "description": "A Sotos syndrome that has_material_basis_in homozygous mutation in the APC2 gene on chromosome 19p13.3.", "url": "https://disease-ontology.org/term/DOID:0112104", "evidence": [ { "id": "0112104", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112104" } ], "weight": 0.0 }, { "disease_id": "DOID:10155", "name": "intestinal cancer", "description": "A gastrointestinal system cancer that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:10155", "evidence": [ { "id": "10155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10155" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "pattern specification process", "id": "GO:0007389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007389", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "beta-catenin destruction complex", "id": "GO:0030877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030877", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" }, { "name": "gamma-catenin binding", "id": "GO:0045295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045295", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8M9QMA5-1", "start_pos": "2010", "end_pos": "2010", "site_lbl": "Thr2010", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2010, "start_aa": "Thr", "end_pos": 2010, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2010", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8M9QN10-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QN10", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QN10" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1418, "chemical_mass": 160400.0, "gene_names": "ankfn1", "protein_name": "Ankyrin repeat and fibronectin type-III domain-containing protein 1", "disease": [], "cellular_component": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QN10", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QN10" } ], "pmid": "" } ], "biological_process": [ { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QN10", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QN10" } ], "pmid": "" }, { "name": "regulation of establishment of bipolar cell polarity", "id": "GO:0061172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061172", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9QN10", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QN10" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N1Z0D3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N1Z0D3", "url": "https://www.uniprot.org/uniprotkb/A0A8N1Z0D3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 709, "chemical_mass": 79809.0, "gene_names": "gja8a;cx50.5;cx79.8;gja8a;si:dkey-18p12.7", "protein_name": "Gap junction protein", "disease": [ { "disease_id": "DOID:0110231", "name": "cataract 1 multiple types", "description": "A cataract that has_material_basis_in heterozygous mutation in the gene encoding the alpha-8 subunit of the gap junction protein (GJA8) on chromosome 1q21.", "url": "https://disease-ontology.org/term/DOID:0110231", "evidence": [ { "id": "0110231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110231" } ], "weight": 0.0 }, { "disease_id": "DOID:10629", "name": "microphthalmia", "description": "An eye disease where one or both eyeballs are abnormally small.", "url": "https://disease-ontology.org/term/DOID:10629", "evidence": [ { "id": "10629", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10629" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "A0A8N1Z0D3", "url": "https://www.uniprot.org/uniprotkb/A0A8N1Z0D3" } ], "pmid": "" }, { "name": "gap junction-mediated intercellular transport", "id": "GO:1990349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990349", "evidence": [ { "database": "UniProtKB", "id": "A0A8N1Z0D3", "url": "https://www.uniprot.org/uniprotkb/A0A8N1Z0D3" } ], "pmid": "" } ], "cellular_component": [ { "name": "connexin complex", "id": "GO:0005922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", "evidence": [ { "database": "UniProtKB", "id": "A0A8N1Z0D3", "url": "https://www.uniprot.org/uniprotkb/A0A8N1Z0D3" } ], "pmid": "" } ], "molecular_function": [ { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "A0A8N1Z0D3", "url": "https://www.uniprot.org/uniprotkb/A0A8N1Z0D3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N1Z0D3-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Thr319", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 319, "start_aa": "Thr", "end_pos": 319, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr319", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7T672-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 762, "chemical_mass": 86267.0, "gene_names": "tnfaip3;tnfaip3", "protein_name": "ubiquitinyl hydrolase 1", "disease": [ { "disease_id": "DOID:0080944", "name": "familial Behcet-like autoinflammatory syndrome", "description": "An autoinflammatory disease that is characterized by characterized by ulceration of mucosal surfaces, particularly in the oral and genital areas and that has_material_basis_in heterozygous mutation in the TNFAIP3 gene on chromosome 6q23.", "url": "https://disease-ontology.org/term/DOID:0080944", "evidence": [ { "id": "0080944", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080944" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:5041", "evidence": [ { "id": "5041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5041" } ], "weight": 0.0 }, { "disease_id": "DOID:5517", "name": "stomach carcinoma", "description": "A stomach cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:5517", "evidence": [ { "id": "5517", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5517" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "negative regulation of innate immune response", "id": "GO:0045824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045824", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "protein deubiquitination involved in ubiquitin-dependent protein catabolic process", "id": "GO:0071947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071947", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T672", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T672" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7T6V3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 979, "chemical_mass": 108954.0, "gene_names": "hcn2b;hcn2b", "protein_name": "", "disease": [ { "disease_id": "DOID:0111310", "name": "familial febrile seizures 2", "description": "A familial febrile seizures that has_material_basis_in variation in a region on chromosome 19p13.3.", "url": "https://disease-ontology.org/term/DOID:0111310", "evidence": [ { "id": "0111310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111310" } ], "weight": 0.0 }, { "disease_id": "DOID:2723", "name": "dermatitis", "description": "A skin disease characterized by itchy, erythematous, vesicular, weeping and crusting patches of skin.", "url": "https://disease-ontology.org/term/DOID:2723", "evidence": [ { "id": "2723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2723" } ], "weight": 0.0 }, { "disease_id": "DOID:9471", "name": "meningitis", "description": "A central nervous system disease that is characterized by an inflammation of the pia-arachnoid meninges. It can be caused by growth of bacteria, fungi, or parasites within the subarachnoid space or by the growth of bacteria or viruses within the meningeal or ependymal cells.", "url": "https://disease-ontology.org/term/DOID:9471", "evidence": [ { "id": "9471", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9471" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" }, { "name": "HCN channel complex", "id": "GO:0098855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098855", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" }, { "name": "regulation of membrane depolarization", "id": "GO:0003254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003254", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" }, { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T6V3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T6V3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7T7D0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T7D0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T7D0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 464, "chemical_mass": 53992.0, "gene_names": "ptdss1b;ptdss1b", "protein_name": "Phosphatidylserine synthase", "disease": [ { "disease_id": "DOID:0111507", "name": "Lenz-Majewski hyperostotic dwarfism", "description": "A syndrome characterized by intellectual disability, sclerosing bone dysplasia, distinct craniofacial, dental, cutaneous and distal-limb anomalies that has_material_basis_in heterozygous mutation in the PTDSS1 gene on chromosome 8q22.1.", "url": "https://disease-ontology.org/term/DOID:0111507", "evidence": [ { "id": "0111507", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111507" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T7D0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T7D0" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylserine biosynthetic process", "id": "GO:0006659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006659", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T7D0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T7D0" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-serine-phosphatidylethanolamine phosphatidyltransferase activity", "id": "GO:0106245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106245", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T7D0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T7D0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7T882-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1524, "chemical_mass": 172688.0, "gene_names": "atp10a;atp10a", "protein_name": "Phospholipid-transporting ATPase", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" }, { "name": "glycosylceramide flippase activity", "id": "GO:0140351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140351", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" }, { "name": "phospholipid-translocating ATPase complex", "id": "GO:1990531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990531", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T882", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T882" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7T8I5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1377, "chemical_mass": 155402.0, "gene_names": "dhx29;DHX29;dhx29", "protein_name": "ATP-dependent RNA helicase DHX29", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "pmid": "" }, { "name": "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides", "id": "GO:0016818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016818", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7T8I5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T8I5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TD42-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 491, "chemical_mass": 54437.0, "gene_names": "htr2aa;htr2aa", "protein_name": "5-hydroxytryptamine receptor 2A", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10933", "name": "obsessive-compulsive disorder", "description": "An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions).", "url": "https://disease-ontology.org/term/DOID:10933", "evidence": [ { "id": "10933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10933" } ], "weight": 0.0 }, { "disease_id": "DOID:12399", "name": "pathological gambling", "description": "An impulse control disorder that involves the uncontrollable impulse to gamble, irrespective of the interference the behaviour has on the individual's life.", "url": "https://disease-ontology.org/term/DOID:12399", "evidence": [ { "id": "12399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12399" } ], "weight": 0.0 }, { "disease_id": "DOID:13948", "name": "bladder neck obstruction", "description": "", "url": "https://disease-ontology.org/term/DOID:13948", "evidence": [ { "id": "13948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13948" } ], "weight": 0.0 }, { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:252", "name": "alcoholic psychosis", "description": "An alcohol-induced mental disorder involving prominent hallucinations and delusions occurring during or shortly after acute alcohol intoxication or withdrawal.", "url": "https://disease-ontology.org/term/DOID:252", "evidence": [ { "id": "252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:252" } ], "weight": 0.0 }, { "disease_id": "DOID:2537", "name": "inflammatory and toxic neuropathy", "description": "A neuropathy that is caused by drug ingestion, drug or chemical abuse, or industrial chemical exposure from the workplace or the environment.", "url": "https://disease-ontology.org/term/DOID:2537", "evidence": [ { "id": "2537", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2537" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3827", "name": "congenital diaphragmatic hernia", "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs.", "url": "https://disease-ontology.org/term/DOID:3827", "evidence": [ { "id": "3827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3827" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:4989", "name": "pancreatitis", "description": "A pancreas disease that is characterized by inflammation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:4989", "evidence": [ { "id": "4989", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4989" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:6088", "name": "acute stress disorder", "description": "An anxiety disorder that has_symptom flashbacks, has_symptom bad dreams, has_symptom frightening thoughts, has_symptom avoidance or has_symptom hyperarousal of PTSD occurring within one month of a traumatic experience as Acute Stress Disorder or ASD.", "url": "https://disease-ontology.org/term/DOID:6088", "evidence": [ { "id": "6088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6088" } ], "weight": 0.0 }, { "disease_id": "DOID:809", "name": "cocaine abuse", "description": "A substance abuse that involves the recurring use of cocaine despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:809", "evidence": [ { "id": "809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:809" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" } ], "molecular_function": [ { "name": "G protein-coupled serotonin receptor activity", "id": "GO:0004993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004993", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "neurotransmitter receptor activity", "id": "GO:0030594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030594", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "serotonin binding", "id": "GO:0051378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051378", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger", "id": "GO:0007187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007187", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "serotonin receptor signaling pathway", "id": "GO:0007210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007210", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "phospholipase C-activating serotonin receptor signaling pathway", "id": "GO:0007208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007208", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "response to xenobiotic stimulus", "id": "GO:0009410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009410", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" }, { "name": "positive regulation of melanin biosynthetic process", "id": "GO:0048023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048023", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TD42", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TD42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TDN4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1230, "chemical_mass": 135343.0, "gene_names": "jag2a;jag2a", "protein_name": "Delta-like protein", "disease": [ { "disease_id": "DOID:0061133", "name": "autosomal recessive limb-girdle muscular dystrophy type 27", "description": "An autosomal recessive limb-girdle muscular dystrophy characterized by progressive muscle weakness primarily affecting the lower limbs and resulting in walking difficulty or loss of ambulation that has_material_basis_in homozygous or compound heterozygous mutation in the JAG2 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0061133", "evidence": [ { "id": "0061133", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061133" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "biological_process": [ { "name": "thyroid gland development", "id": "GO:0030878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030878", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "hematopoietic stem cell differentiation", "id": "GO:0060218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060218", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901222", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "embryonic organ development", "id": "GO:0048568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048568", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "exocrine pancreas development", "id": "GO:0031017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031017", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "hepaticobiliary system development", "id": "GO:0061008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061008", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDN4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7TDN4-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Thr369", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 369, "start_aa": "Thr", "end_pos": 369, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr369", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8N7TDN4-1", "start_pos": "777", "end_pos": "777", "site_lbl": "Thr777", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 777, "start_aa": "Thr", "end_pos": 777, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr777", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TDX0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 619, "chemical_mass": 69454.0, "gene_names": "pimr117;pimr117", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDX0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDX0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDX0" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDX0" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TDX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TE02-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 918, "chemical_mass": 104577.0, "gene_names": "pde11al;pde11al", "protein_name": "Phosphodiesterase", "disease": [ { "disease_id": "DOID:0070547", "name": "primary pigmented nodular adrenocortical disease 2", "description": "A primary pigmented nodular adrenocortical disease that has_material_basis_in heterozygous mutation in the PDE11A gene on chromosome 2q31.2.", "url": "https://disease-ontology.org/term/DOID:0070547", "evidence": [ { "id": "0070547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070547" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "pmid": "" }, { "name": "negative regulation of cGMP-mediated signaling", "id": "GO:0010754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010754", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "pmid": "" }, { "name": "negative regulation of cAMP/PKA signal transduction", "id": "GO:0141162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141162", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "pmid": "" }, { "name": "3',5'-cyclic-GMP phosphodiesterase activity", "id": "GO:0047555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047555", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "pmid": "" }, { "name": "3',5'-cyclic-AMP phosphodiesterase activity", "id": "GO:0004115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004115", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "pmid": "" }, { "name": "3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity", "id": "GO:0004118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004118", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE02" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TE51-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1173, "chemical_mass": 131629.0, "gene_names": "dhx30;dhx30", "protein_name": "ATP-dependent RNA helicase DHX30", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "G-quadruplex RNA binding", "id": "GO:0002151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002151", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cellular response to heat", "id": "GO:1900034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900034", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "social behavior", "id": "GO:0035176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035176", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" }, { "name": "regulation of circadian sleep/wake cycle", "id": "GO:0042749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042749", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TE51", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TE51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7TE51-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Thr243", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 243, "start_aa": "Thr", "end_pos": 243, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr243", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TED1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TED1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 510, "chemical_mass": 58110.0, "gene_names": "ptk6a;ptk6a", "protein_name": "Tyrosine-protein kinase", "disease": [ { "disease_id": "DOID:10155", "name": "intestinal cancer", "description": "A gastrointestinal system cancer that is located_in the intestine.", "url": "https://disease-ontology.org/term/DOID:10155", "evidence": [ { "id": "10155", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10155" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:305", "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TED1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TED1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TED1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TED1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TED1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TED1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TEK0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1214, "chemical_mass": 138868.0, "gene_names": "atp8b4;atp8b4", "protein_name": "Phospholipid-transporting ATPase", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" }, { "name": "phospholipid transporter activity", "id": "GO:0005548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005548", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" }, { "name": "ATPase-coupled intramembrane lipid transporter activity", "id": "GO:0140326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140326", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" }, { "name": "flippase activity", "id": "GO:0140327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140327", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEK0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TER6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 459, "chemical_mass": 52098.0, "gene_names": "gabrd;gabrd", "protein_name": "Gamma-aminobutyric acid receptor subunit delta", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:9478", "name": "postpartum depression", "description": "An endogenous depression that involves intense, sustained and sometimes disabling depression experienced by women after giving birth.", "url": "https://disease-ontology.org/term/DOID:9478", "evidence": [ { "id": "9478", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9478" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" }, { "name": "GABA-A receptor complex", "id": "GO:1902711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902711", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" } ], "molecular_function": [ { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" }, { "name": "GABA-A receptor activity", "id": "GO:0004890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004890", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" }, { "name": "extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005230", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" } ], "biological_process": [ { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" }, { "name": "synaptic transmission, GABAergic", "id": "GO:0051932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051932", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TER6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TER6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TES9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TES9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 502, "chemical_mass": 57526.0, "gene_names": "hyal2b;hyal2b", "protein_name": "Hyaluronidase", "disease": [ { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TES9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TES9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TES9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TES9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9" } ], "pmid": "" }, { "name": "hyaluronan catabolic process", "id": "GO:0030214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030214", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TES9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9" } ], "pmid": "" } ], "molecular_function": [ { "name": "hyalurononglucosaminidase activity", "id": "GO:0004415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004415", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TES9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9" } ], "pmid": "" }, { "name": "hyaluronoglucuronidase activity", "id": "GO:0033906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033906", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TES9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7TES9-1", "start_pos": "394", "end_pos": "394", "site_lbl": "Asn394", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 394, "start_aa": "Asn", "end_pos": 394, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn394", "evidence": [ { "id": "A0A8N7TES9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TES9#ptm_processing" }, { "id": "PIRSR038193-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038193-2" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7TF16-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TF16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF16" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 994, "chemical_mass": 114556.0, "gene_names": "trhde.2;trhde.2", "protein_name": "Aminopeptidase", "disease": [], "molecular_function": [ { "name": "pyroglutamyl-peptidase activity", "id": "GO:0016920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016920", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TF16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF16" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TF16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF16" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TF16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF16" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TF16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF16" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TF16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF16" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TF16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF16" } ], "pmid": "" }, { "name": "peptide catabolic process", "id": "GO:0043171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043171", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7TF16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF16" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UQR8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1140, "chemical_mass": 125524.0, "gene_names": "hcn4;hcn4", "protein_name": "", "disease": [ { "disease_id": "DOID:0110225", "name": "Brugada syndrome 8", "description": "A Brugada syndrome that has_material_basis_in heterozygous mutation in the HCN4 gene on chromosome 15q24.", "url": "https://disease-ontology.org/term/DOID:0110225", "evidence": [ { "id": "0110225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110225" } ], "weight": 0.0 }, { "disease_id": "DOID:11119", "name": "Gilles de la Tourette syndrome", "description": "A tic disorder that is characterized by multiple physical (motor) tics and at least one vocal (phonic) tic present for more than a year.", "url": "https://disease-ontology.org/term/DOID:11119", "evidence": [ { "id": "11119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11119" } ], "weight": 0.0 }, { "disease_id": "DOID:13884", "name": "sick sinus syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:13884", "evidence": [ { "id": "13884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13884" } ], "weight": 0.0 }, { "disease_id": "DOID:1827", "name": "generalized epilepsy", "description": "An epilepsy syndrome that is characterized by generalised seizures with no apparent cause which arise from many independent foci (multifocal epilepsies) or from epileptic circuits that involve the whole brain.", "url": "https://disease-ontology.org/term/DOID:1827", "evidence": [ { "id": "1827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1827" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" }, { "name": "HCN channel complex", "id": "GO:0098855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098855", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" } ], "biological_process": [ { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" }, { "name": "regulation of membrane depolarization", "id": "GO:0003254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003254", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" }, { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQR8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7UQR8-1", "start_pos": "732", "end_pos": "732", "site_lbl": "Thr732", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 732, "start_aa": "Thr", "end_pos": 732, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr732", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UQX6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQX6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQX6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1009, "chemical_mass": 111945.0, "gene_names": "map3k9;map3k9", "protein_name": "Mitogen-activated protein kinase kinase kinase", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQX6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQX6" } ], "pmid": "" }, { "name": "JUN kinase kinase kinase activity", "id": "GO:0004706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004706", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQX6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQX6" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQX6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQX6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQX6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQX6" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQX6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQX6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7UQX6-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8N7UQX6-1", "start_pos": "870", "end_pos": "870", "site_lbl": "Thr870", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 870, "start_aa": "Thr", "end_pos": 870, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr870", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8N7UQX6-1", "start_pos": "960", "end_pos": "960", "site_lbl": "Thr960", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 960, "start_aa": "Thr", "end_pos": 960, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr960", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UQZ5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 4005, "chemical_mass": 456913.0, "gene_names": "dnah7;dnah7", "protein_name": "Dynein axonemal heavy chain 7", "disease": [ { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" }, { "name": "axonemal dynein complex", "id": "GO:0005858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005858", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" }, { "name": "determination of liver left/right asymmetry", "id": "GO:0071910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071910", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7UQZ5-1", "start_pos": "1959", "end_pos": "1959", "site_lbl": "Thr1959", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1959, "start_aa": "Thr", "end_pos": 1959, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1959", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8N7UQZ5-1", "start_pos": "2084", "end_pos": "2084", "site_lbl": "Thr2084", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2084, "start_aa": "Thr", "end_pos": 2084, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2084", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8N7UQZ5-1", "start_pos": "2151", "end_pos": "2151", "site_lbl": "Thr2151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2151, "start_aa": "Thr", "end_pos": 2151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2151", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0A8N7UQZ5-1", "start_pos": "2540", "end_pos": "2540", "site_lbl": "Thr2540", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2540, "start_aa": "Thr", "end_pos": 2540, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2540", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UUT2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 497, "chemical_mass": 55075.0, "gene_names": "entpd2a.2;entpd2a.2", "protein_name": "apyrase", "disease": [ { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" }, { "name": "GDP phosphatase activity", "id": "GO:0004382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004382", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" }, { "name": "UDP phosphatase activity", "id": "GO:0045134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045134", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" }, { "name": "ribonucleoside triphosphate phosphatase activity", "id": "GO:0017111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017111", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" } ], "biological_process": [ { "name": "response to ethanol", "id": "GO:0045471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" }, { "name": "response to copper ion", "id": "GO:0046688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046688", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" }, { "name": "nucleoside diphosphate catabolic process", "id": "GO:0009134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009134", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" }, { "name": "cellular response to methanol", "id": "GO:0071405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071405", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUT2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A8N7UUT2-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Thr188", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UVH6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 862, "chemical_mass": 98960.0, "gene_names": "pkd2l1;pkd2l1", "protein_name": "", "disease": [ { "disease_id": "DOID:0110859", "name": "polycystic kidney disease 2", "description": "A autosomal dominant polycystic kidney disease that has_material_basis_in autosomal dominant inheritance of mutation in the PKD2 gene on chromosome 4q22.1.", "url": "https://disease-ontology.org/term/DOID:0110859", "evidence": [ { "id": "0110859", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110859" } ], "weight": 0.0 }, { "disease_id": "DOID:898", "name": "autosomal dominant polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion.", "url": "https://disease-ontology.org/term/DOID:898", "evidence": [ { "id": "898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:898" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "muscle alpha-actinin binding", "id": "GO:0051371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051371", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "calcium-activated potassium channel activity", "id": "GO:0015269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015269", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" } ], "biological_process": [ { "name": "mechanosensory behavior", "id": "GO:0007638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007638", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "response to mechanical stimulus", "id": "GO:0009612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009612", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "detection of mechanical stimulus", "id": "GO:0050982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050982", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "notochord development", "id": "GO:0030903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030903", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVH6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UVV0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVV0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVV0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 506, "chemical_mass": 56805.0, "gene_names": "rps6kb1a;rps6kb1a", "protein_name": "Ribosomal protein S6 kinase", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:4194", "name": "glucose metabolism disease", "description": "A carbohydrate metabolic disorder that is characterized by blood glucose levels which cannot be maintained within the normal range.", "url": "https://disease-ontology.org/term/DOID:4194", "evidence": [ { "id": "4194", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4194" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 }, { "disease_id": "DOID:898", "name": "autosomal dominant polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion.", "url": "https://disease-ontology.org/term/DOID:898", "evidence": [ { "id": "898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:898" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVV0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVV0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVV0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVV0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVV0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVV0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVV0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVV0" } ], "pmid": "" } ], "biological_process": [ { "name": "TORC1 signaling", "id": "GO:0038202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038202", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVV0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVV0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UW22-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1312, "chemical_mass": 153665.0, "gene_names": "rad50;rad50", "protein_name": "", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "Mre11 complex", "id": "GO:0030870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030870", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "double-stranded telomeric DNA binding", "id": "GO:0003691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003691", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "G-quadruplex DNA binding", "id": "GO:0051880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051880", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "single-stranded telomeric DNA binding", "id": "GO:0043047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043047", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" } ], "biological_process": [ { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "telomere maintenance via telomerase", "id": "GO:0007004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007004", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "chromosome organization involved in meiotic cell cycle", "id": "GO:0070192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070192", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW22", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UZM3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 196, "chemical_mass": 21865.0, "gene_names": "cmlc1;cmlc1;zgc:103441", "protein_name": "", "disease": [ { "disease_id": "DOID:0050650", "name": "familial atrial fibrillation", "description": "An atrial fibrillation that has_material_basis_in autosomal dominant inheritance of the familial atrial fibrillation (ATFB) genes.", "url": "https://disease-ontology.org/term/DOID:0050650", "evidence": [ { "id": "0050650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050650" } ], "weight": 0.0 }, { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ventricular cardiac myofibril assembly", "id": "GO:0055005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055005", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "pmid": "" }, { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "pmid": "" }, { "name": "heart morphogenesis", "id": "GO:0003007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003007", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "pmid": "" }, { "name": "cardiac muscle tissue development", "id": "GO:0048738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048738", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "pmid": "" }, { "name": "ventricular cardiac muscle cell development", "id": "GO:0055015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055015", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "pmid": "" } ], "cellular_component": [ { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZM3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZM3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UZN6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 466, "chemical_mass": 53607.0, "gene_names": "angptl3;angptl3;fb60e11;fb66h02;wu:fb60e11;wu:fb66h02;zgc:111943", "protein_name": "Angiopoietin-related protein 3", "disease": [ { "disease_id": "DOID:0111061", "name": "familial hypobetalipoproteinemia 2", "description": "A hypobetalipoproteinemia that has_material_basis_in homozygous or compound heterozygous mutation in the ANGPTL3 gene on chromosome 1p31.", "url": "https://disease-ontology.org/term/DOID:0111061", "evidence": [ { "id": "0111061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111061" } ], "weight": 0.0 } ], "biological_process": [ { "name": "hepatocyte proliferation", "id": "GO:0072574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072574", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "negative regulation of very-low-density lipoprotein particle remodeling", "id": "GO:0010903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010903", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "regulation of chylomicron remodeling", "id": "GO:0090318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090318", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" }, { "name": "phospholipase inhibitor activity", "id": "GO:0004859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004859", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZN6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UZX0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1271, "chemical_mass": 145203.0, "gene_names": "iars1;fi46h05;iars1;iars;wu:fi46h05;zgc:63790", "protein_name": "Isoleucine--tRNA ligase, cytoplasmic", "disease": [], "molecular_function": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX0" } ], "pmid": "" }, { "name": "isoleucine-tRNA ligase activity", "id": "GO:0004822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004822", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX0" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX0" } ], "pmid": "" } ], "biological_process": [ { "name": "isoleucyl-tRNA aminoacylation", "id": "GO:0006428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006428", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX0" } ], "pmid": "" }, { "name": "regulation of sprouting angiogenesis", "id": "GO:1903670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903670", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7UZX7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 562, "chemical_mass": 61397.0, "gene_names": "slc1a2b;eaat2;fj34b12;slc1a2b;slc1a2;wu:fj34b12;zgc:65897", "protein_name": "Amino acid transporter", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0080442", "name": "developmental and epileptic encephalopathy 41", "description": "A developmental and epileptic encephalopathy characterized by onset in the first days or weeks of life of seizures, severely impaired psychomotor development, and brain anomalies including delayed myelination, thin corpus callosum, and cerebral atrophy that has_material_basis_in heterozygous mutation in the SLC1A2 gene on chromosome 11p13.", "url": "https://disease-ontology.org/term/DOID:0080442", "evidence": [ { "id": "0080442", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080442" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:11206", "name": "opioid abuse", "description": "A substance abuse that involves the recurring use of opioid drugs despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:11206", "evidence": [ { "id": "11206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11206" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1742", "name": "drug psychosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1742", "evidence": [ { "id": "1742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1742" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "pmid": "" } ], "molecular_function": [ { "name": "neutral L-amino acid transmembrane transporter activity", "id": "GO:0015175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "pmid": "" }, { "name": "glutamate:sodium symporter activity", "id": "GO:0015501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015501", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of glutamate uptake involved in transmission of nerve impulse", "id": "GO:0051946", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051946", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "pmid": "" }, { "name": "L-glutamate import across plasma membrane", "id": "GO:0098712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098712", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "pmid": "" }, { "name": "larval locomotory behavior", "id": "GO:0008345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008345", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "pmid": "" }, { "name": "L-aspartate transmembrane transport", "id": "GO:0070778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070778", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0A8N7V0N6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 391, "chemical_mass": 45414.0, "gene_names": "ogg1;ogg1;zgc:158858", "protein_name": "N-glycosylase/DNA lyase", "disease": [ { "disease_id": "DOID:0002116", "name": "pterygium", "description": "A corneal disease that is characterized by a triangular tissue growth located_in cornea of the eye that is the result of collagen degeneration and fibrovascular proliferation.", "url": "https://disease-ontology.org/term/DOID:0002116", "evidence": [ { "id": "0002116", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0002116" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:1070", "name": "primary open angle glaucoma", "description": "An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.", "url": "https://disease-ontology.org/term/DOID:1070", "evidence": [ { "id": "1070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1070" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy.", "url": "https://disease-ontology.org/term/DOID:11714", "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ], "weight": 0.0 }, { "disease_id": "DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.", "url": "https://disease-ontology.org/term/DOID:12361", "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:2237", "name": "hepatitis", "description": "A liver disease that is characterized as an inflammation of the liver.", "url": "https://disease-ontology.org/term/DOID:2237", "evidence": [ { "id": "2237", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2237" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2513", "name": "basal cell carcinoma", "description": "A skin carcinoma affecting basal cells.", "url": "https://disease-ontology.org/term/DOID:2513", "evidence": [ { "id": "2513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2513" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:3314", "name": "angiomyolipoma", "description": "A cell type benign neoplasm that is primarily located in the kidneys but may be found in the lungs, liver or other organs and is derived from perivascular epithelioid cells.", "url": "https://disease-ontology.org/term/DOID:3314", "evidence": [ { "id": "3314", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3314" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:5520", "name": "head and neck squamous cell carcinoma", "description": "A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.", "url": "https://disease-ontology.org/term/DOID:5520", "evidence": [ { "id": "5520", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5520" } ], "weight": 0.0 }, { "disease_id": "DOID:678", "name": "progressive supranuclear palsy", "description": "A movement disease that is characterized by serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. It involves gradual deterioration and death of specific volumes of the brain.", "url": "https://disease-ontology.org/term/DOID:678", "evidence": [ { "id": "678", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:678" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging.", "url": "https://disease-ontology.org/term/DOID:9669", "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "8-oxo-7,8-dihydroguanine DNA N-glycosylase activity", "id": "GO:0034039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034039", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0140078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140078", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "cardiac muscle cell development", "id": "GO:0055013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055013", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "regulation of neuron projection development", "id": "GO:0010975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010975", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "base-excision repair, AP site formation", "id": "GO:0006285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006285", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" }, { "name": "heart rudiment development", "id": "GO:0003313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003313", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7V0N6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7V0N6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0AUR5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0AUR5", "url": "https://www.uniprot.org/uniprotkb/A0AUR5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 446, "chemical_mass": 50111.0, "gene_names": "mindy3;carp;fam188a;fb94a02;mindy3;wu:fb94a02;wu:fy30f06;zgc:153892", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-3", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AUR5", "url": "https://www.uniprot.org/uniprotkb/A0AUR5" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0AUR5", "url": "https://www.uniprot.org/uniprotkb/A0AUR5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0AUR5", "url": "https://www.uniprot.org/uniprotkb/A0AUR5" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "A0AUR5", "url": "https://www.uniprot.org/uniprotkb/A0AUR5" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0AUR5", "url": "https://www.uniprot.org/uniprotkb/A0AUR5" } ], "pmid": "" }, { "name": "K48-linked deubiquitinase activity", "id": "GO:1990380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990380", "evidence": [ { "database": "UniProtKB", "id": "A0AUR5", "url": "https://www.uniprot.org/uniprotkb/A0AUR5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMF7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 794, "chemical_mass": 89608.0, "gene_names": "haus6;fam29a;haus6;wu:fd21a02;zgc:153242", "protein_name": "HAUS augmin-like complex subunit 6", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "pmid": "" }, { "name": "HAUS complex", "id": "GO:0070652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070652", "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "pmid": "" }, { "name": "mitotic spindle microtubule", "id": "GO:1990498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990498", "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "A0JMF7", "url": "https://www.uniprot.org/uniprotkb/A0JMF7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMG1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 392, "chemical_mass": 44248.0, "gene_names": "spoplb;im:6961637;spoplb;zgc:153365", "protein_name": "Speckle-type POZ protein-like B", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "pmid": "" }, { "name": "regulation of proteolysis", "id": "GO:0030162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030162", "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0JMG1", "url": "https://www.uniprot.org/uniprotkb/A0JMG1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0JMG1-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Thr6", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6, "start_aa": "Thr", "end_pos": 6, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMI9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMI9", "url": "https://www.uniprot.org/uniprotkb/A0JMI9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 762, "chemical_mass": 83643.0, "gene_names": "gfm2;EF-G2mt;RRF2mt;efg2;gfm2;mEF-G 2;si:dkey-35i22.3;zgc:153835", "protein_name": "Ribosome-releasing factor 2, mitochondrial", "disease": [ { "disease_id": "DOID:0111475", "name": "combined oxidative phosphorylation deficiency 39", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the GFM2 gene on chromosome 5q13.3.", "url": "https://disease-ontology.org/term/DOID:0111475", "evidence": [ { "id": "0111475", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111475" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "A0JMI9", "url": "https://www.uniprot.org/uniprotkb/A0JMI9" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0JMI9", "url": "https://www.uniprot.org/uniprotkb/A0JMI9" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0JMI9", "url": "https://www.uniprot.org/uniprotkb/A0JMI9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0JMI9", "url": "https://www.uniprot.org/uniprotkb/A0JMI9" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0JMI9", "url": "https://www.uniprot.org/uniprotkb/A0JMI9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMK9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 863, "chemical_mass": 97223.0, "gene_names": "chaf1a;CAF-Ip150;caip150;ch211-129c21.3;wu:fd14g10;zgc:153930", "protein_name": "Chromatin assembly factor 1 subunit A", "disease": [ { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:769", "name": "neuroblastoma", "description": "An autonomic nervous system neoplasm that derives_from immature nerve cells.", "url": "https://disease-ontology.org/term/DOID:769", "evidence": [ { "id": "769", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:769" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" } ], "pmid": "" }, { "name": "CAF-1 complex", "id": "GO:0033186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033186", "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" } ], "pmid": "" }, { "name": "DNA replication-dependent chromatin assembly", "id": "GO:0006335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006335", "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0JMK9-1", "start_pos": "859", "end_pos": "859", "site_lbl": "Thr859", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 859, "start_aa": "Thr", "end_pos": 859, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr859", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0JMK9-1", "start_pos": "111", "end_pos": "111", "site_lbl": "Thr111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A0JMK9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A0JMK9" } ] } ] }, { "uniprot_canonical_ac": "A0JMK9-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0JMK9", "url": "https://www.uniprot.org/uniprotkb/A0JMK9" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A0JMK9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A0JMK9" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMM9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMM9", "url": "https://www.uniprot.org/uniprotkb/A0JMM9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 161, "chemical_mass": 18132.0, "gene_names": "ggact.1;GGACT A;GGACT C;GGACT;ggact.1;zgc:154024", "protein_name": "Gamma-glutamylaminecyclotransferase A", "disease": [], "biological_process": [ { "name": "modified amino acid catabolic process", "id": "GO:0042219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042219", "evidence": [ { "database": "UniProtKB", "id": "A0JMM9", "url": "https://www.uniprot.org/uniprotkb/A0JMM9" } ], "pmid": "" } ], "molecular_function": [ { "name": "gamma-glutamylaminecyclotransferase activity", "id": "GO:0061929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061929", "evidence": [ { "database": "UniProtKB", "id": "A0JMM9", "url": "https://www.uniprot.org/uniprotkb/A0JMM9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0JMM9", "url": "https://www.uniprot.org/uniprotkb/A0JMM9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMQ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMQ0", "url": "https://www.uniprot.org/uniprotkb/A0JMQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 777, "chemical_mass": 88365.0, "gene_names": "bop1;bop1;id:ibd1283;si:ch211-251g8.2;si:ch211-251g8.4;zgc:154135", "protein_name": "Ribosome biogenesis protein bop1", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ0", "url": "https://www.uniprot.org/uniprotkb/A0JMQ0" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ0", "url": "https://www.uniprot.org/uniprotkb/A0JMQ0" } ], "pmid": "" }, { "name": "PeBoW complex", "id": "GO:0070545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070545", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ0", "url": "https://www.uniprot.org/uniprotkb/A0JMQ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ0", "url": "https://www.uniprot.org/uniprotkb/A0JMQ0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ0", "url": "https://www.uniprot.org/uniprotkb/A0JMQ0" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ0", "url": "https://www.uniprot.org/uniprotkb/A0JMQ0" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000466", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ0", "url": "https://www.uniprot.org/uniprotkb/A0JMQ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JMQ7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JMQ7", "url": "https://www.uniprot.org/uniprotkb/A0JMQ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 440, "chemical_mass": 51209.0, "gene_names": "mtus1a;fa17d11;mtus1;wu:fa17d11;wu:fi18f08;zgc:154168", "protein_name": "Microtubule-associated tumor suppressor 1 homolog A", "disease": [ { "disease_id": "DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue.", "url": "https://disease-ontology.org/term/DOID:0050865", "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:4001", "name": "ovarian carcinoma", "description": "An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:4001", "evidence": [ { "id": "4001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4001" } ], "weight": 0.0 }, { "disease_id": "DOID:4866", "name": "salivary gland adenoid cystic carcinoma", "description": "A salivary gland carcinoma that is characterized by a distinctive pattern in which abnormal nests or cords of epithelial cells surround and/or infiltrate ducts or glandular structures within the affected organ. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes.", "url": "https://disease-ontology.org/term/DOID:4866", "evidence": [ { "id": "4866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4866" } ], "weight": 0.0 }, { "disease_id": "DOID:4948", "name": "gallbladder carcinoma", "description": "A gallbladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4948", "evidence": [ { "id": "4948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4948" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ7", "url": "https://www.uniprot.org/uniprotkb/A0JMQ7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ7", "url": "https://www.uniprot.org/uniprotkb/A0JMQ7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ7", "url": "https://www.uniprot.org/uniprotkb/A0JMQ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ7", "url": "https://www.uniprot.org/uniprotkb/A0JMQ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0JMQ7", "url": "https://www.uniprot.org/uniprotkb/A0JMQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0JPE9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 529, "chemical_mass": 58653.0, "gene_names": "gk5;fd15d09;fk85h05;gk5;im:7160691;wu:fc06f04;wu:fd15d09;wu:fk85h05;zgc:152983", "protein_name": "Glycerol kinase 5", "disease": [], "molecular_function": [ { "name": "glycerol kinase activity", "id": "GO:0004370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004370", "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "pmid": "" } ], "biological_process": [ { "name": "glycerol catabolic process", "id": "GO:0019563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019563", "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "pmid": "" }, { "name": "glycerol-3-phosphate biosynthetic process", "id": "GO:0046167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046167", "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "pmid": "" }, { "name": "triglyceride metabolic process", "id": "GO:0006641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641", "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "pmid": "" }, { "name": "glycerol metabolic process", "id": "GO:0006071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006071", "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0JPE9", "url": "https://www.uniprot.org/uniprotkb/A0JPE9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0MGZ5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0MGZ5", "url": "https://www.uniprot.org/uniprotkb/A0MGZ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 407, "chemical_mass": 47878.0, "gene_names": "hs6st1b;hs6st1b", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "disease": [ { "disease_id": "DOID:0090075", "name": "hypogonadotropic hypogonadism 15 with or without anosmia", "description": "A hypogonadotropic hypogonadism that has_material_basis_in mutation in the HS6ST1 gene on chromosome 2q14, sometimes in association with mutations in other genes.", "url": "https://disease-ontology.org/term/DOID:0090075", "evidence": [ { "id": "0090075", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090075" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0MGZ5", "url": "https://www.uniprot.org/uniprotkb/A0MGZ5" } ], "pmid": "" } ], "biological_process": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "A0MGZ5", "url": "https://www.uniprot.org/uniprotkb/A0MGZ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparan sulfate 6-sulfotransferase activity", "id": "GO:0017095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017095", "evidence": [ { "database": "UniProtKB", "id": "A0MGZ5", "url": "https://www.uniprot.org/uniprotkb/A0MGZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0MGZ5-1", "start_pos": "215", "end_pos": "215", "site_lbl": "Thr215", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A0MGZ5-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Asn262", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 262, "start_aa": "Asn", "end_pos": 262, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn262", "evidence": [ { "id": "A0MGZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0MGZ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A0MGZ5-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Asn318", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 318, "start_aa": "Asn", "end_pos": 318, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn318", "evidence": [ { "id": "A0MGZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0MGZ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A0MGZ5-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Asn329", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 329, "start_aa": "Asn", "end_pos": 329, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn329", "evidence": [ { "id": "A0MGZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0MGZ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A0MGZ5-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A0MS83-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 808, "chemical_mass": 90507.0, "gene_names": "znf148;ZBP-89;fb06h05;si:dkey-101k6.6;wu:fb06h05;zbp89;zfp149;zgc:165342;znf148", "protein_name": "Zinc finger protein 148", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0MS83", "url": "https://www.uniprot.org/uniprotkb/A0MS83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1A5V9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1A5V9", "url": "https://www.uniprot.org/uniprotkb/A1A5V9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 296, "chemical_mass": 32739.0, "gene_names": "elp5;Rai12;derp6;elp5;rai12;zgc:158278;zgc:158285", "protein_name": "Elongator complex protein 5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1A5V9", "url": "https://www.uniprot.org/uniprotkb/A1A5V9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1A5V9", "url": "https://www.uniprot.org/uniprotkb/A1A5V9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A1A5V9", "url": "https://www.uniprot.org/uniprotkb/A1A5V9" } ], "pmid": "" }, { "name": "elongator holoenzyme complex", "id": "GO:0033588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033588", "evidence": [ { "database": "UniProtKB", "id": "A1A5V9", "url": "https://www.uniprot.org/uniprotkb/A1A5V9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A1A5V9", "url": "https://www.uniprot.org/uniprotkb/A1A5V9" } ], "pmid": "" }, { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "A1A5V9", "url": "https://www.uniprot.org/uniprotkb/A1A5V9" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "A1A5V9", "url": "https://www.uniprot.org/uniprotkb/A1A5V9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1A5V9-1", "start_pos": "269", "end_pos": "269", "site_lbl": "Thr269", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1A5X2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1A5X2", "url": "https://www.uniprot.org/uniprotkb/A1A5X2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 489, "chemical_mass": 54220.0, "gene_names": "fbxl7;fbxl7;zgc:158339;zgc:158346", "protein_name": "F-box/LRR-repeat protein 7", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A1A5X2", "url": "https://www.uniprot.org/uniprotkb/A1A5X2" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A1A5X2", "url": "https://www.uniprot.org/uniprotkb/A1A5X2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A1A5X2", "url": "https://www.uniprot.org/uniprotkb/A1A5X2" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A1A5X2", "url": "https://www.uniprot.org/uniprotkb/A1A5X2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1A5Y0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 811, "chemical_mass": 89142.0, "gene_names": "nell2a;nell2a;nell2;wu:fj43h11;zgc:158375", "protein_name": "Protein kinase C-binding protein NELL2a", "disease": [ { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" }, { "name": "protein kinase C binding", "id": "GO:0005080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005080", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" } ], "biological_process": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" }, { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A1A5Y0", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1A5Y0-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Asn222", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 222, "start_aa": "Asn", "end_pos": 222, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn222", "evidence": [ { "id": "A1A5Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A1A5Y0-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Asn290", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 290, "start_aa": "Asn", "end_pos": 290, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn290", "evidence": [ { "id": "A1A5Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A1A5Y0-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Asn295", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 295, "start_aa": "Asn", "end_pos": 295, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn295", "evidence": [ { "id": "A1A5Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A1A5Y0-1", "start_pos": "515", "end_pos": "515", "site_lbl": "Asn515", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 515, "start_aa": "Asn", "end_pos": 515, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn515", "evidence": [ { "id": "A1A5Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A1A5Y0-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Asn613", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 613, "start_aa": "Asn", "end_pos": 613, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn613", "evidence": [ { "id": "A1A5Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A1A5Y0-1", "start_pos": "633", "end_pos": "633", "site_lbl": "Asn633", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 633, "start_aa": "Asn", "end_pos": 633, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn633", "evidence": [ { "id": "A1A5Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y0#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1A5Z0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1A5Z0", "url": "https://www.uniprot.org/uniprotkb/A1A5Z0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 339, "chemical_mass": 38003.0, "gene_names": "g6pc3;g6pc3;zgc:158425", "protein_name": "Glucose-6-phosphatase 3", "disease": [ { "disease_id": "DOID:0112136", "name": "severe congenital neutropenia 4", "description": "A severe congenital neutropenia that has_material_basis_in homozygous or compound heterozygous mutation in the G6PC3 gene on chromosome 17q21.31.", "url": "https://disease-ontology.org/term/DOID:0112136", "evidence": [ { "id": "0112136", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112136" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1A5Z0", "url": "https://www.uniprot.org/uniprotkb/A1A5Z0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A1A5Z0", "url": "https://www.uniprot.org/uniprotkb/A1A5Z0" } ], "pmid": "" } ], "biological_process": [ { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "A1A5Z0", "url": "https://www.uniprot.org/uniprotkb/A1A5Z0" } ], "pmid": "" }, { "name": "hematopoietic progenitor cell differentiation", "id": "GO:0002244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", "evidence": [ { "database": "UniProtKB", "id": "A1A5Z0", "url": "https://www.uniprot.org/uniprotkb/A1A5Z0" } ], "pmid": "" }, { "name": "glucose 6-phosphate metabolic process", "id": "GO:0051156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051156", "evidence": [ { "database": "UniProtKB", "id": "A1A5Z0", "url": "https://www.uniprot.org/uniprotkb/A1A5Z0" } ], "pmid": "" } ], "molecular_function": [ { "name": "glucose-6-phosphatase activity", "id": "GO:0004346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004346", "evidence": [ { "database": "UniProtKB", "id": "A1A5Z0", "url": "https://www.uniprot.org/uniprotkb/A1A5Z0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L1M4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L1M4", "url": "https://www.uniprot.org/uniprotkb/A1L1M4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 426, "chemical_mass": 46589.0, "gene_names": "ppp4r2b;ppp4r2b;wu:fa17h08;wu:fc23g05", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2-B", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1L1M4", "url": "https://www.uniprot.org/uniprotkb/A1L1M4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1L1M4", "url": "https://www.uniprot.org/uniprotkb/A1L1M4" } ], "pmid": "" }, { "name": "protein phosphatase 4 complex", "id": "GO:0030289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030289", "evidence": [ { "database": "UniProtKB", "id": "A1L1M4", "url": "https://www.uniprot.org/uniprotkb/A1L1M4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A1L1M4", "url": "https://www.uniprot.org/uniprotkb/A1L1M4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1L1M4-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Thr395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A1L1M4-1", "start_pos": "370", "end_pos": "370", "site_lbl": "Ser370", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A1L1M4", "url": "https://www.uniprot.org/uniprotkb/A1L1M4" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A1L1M4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A1L1M4" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L1P9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L1P9", "url": "https://www.uniprot.org/uniprotkb/A1L1P9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 590, "chemical_mass": 63759.0, "gene_names": "slc47a1;mate1;mate3;mate6;slc47a1;slc47a2.1;slc47a2;zgc:113362;zgc:158231", "protein_name": "Multidrug and toxin extrusion protein 1", "disease": [], "molecular_function": [ { "name": "xenobiotic transmembrane transporter activity", "id": "GO:0042910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042910", "evidence": [ { "database": "UniProtKB", "id": "A1L1P9", "url": "https://www.uniprot.org/uniprotkb/A1L1P9" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A1L1P9", "url": "https://www.uniprot.org/uniprotkb/A1L1P9" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A1L1P9", "url": "https://www.uniprot.org/uniprotkb/A1L1P9" } ], "pmid": "" } ], "biological_process": [ { "name": "organic cation transport", "id": "GO:0015695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015695", "evidence": [ { "database": "UniProtKB", "id": "A1L1P9", "url": "https://www.uniprot.org/uniprotkb/A1L1P9" } ], "pmid": "" }, { "name": "xenobiotic detoxification by transmembrane export across the plasma membrane", "id": "GO:1990961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990961", "evidence": [ { "database": "UniProtKB", "id": "A1L1P9", "url": "https://www.uniprot.org/uniprotkb/A1L1P9" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1L1P9", "url": "https://www.uniprot.org/uniprotkb/A1L1P9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A1L1P9", "url": "https://www.uniprot.org/uniprotkb/A1L1P9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L1R0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 585, "chemical_mass": 67499.0, "gene_names": "shq1;zgc:158255", "protein_name": "Protein SHQ1 homolog", "disease": [ { "disease_id": "DOID:0060955", "name": "dystonia 35, childhood-onset", "description": "A dystonia characterized by the onset of a dystonic movement disorder in the first year of life that has_material_basis_in compound heterozygous mutation in the SHQ1 gene on chromosome 3p13.", "url": "https://disease-ontology.org/term/DOID:0060955", "evidence": [ { "id": "0060955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060955" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein-RNA complex assembly", "id": "GO:0022618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022618", "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" } ], "pmid": "" }, { "name": "box H/ACA snoRNP assembly", "id": "GO:0000493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000493", "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1L1R0-1", "start_pos": "536", "end_pos": "536", "site_lbl": "Thr536", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A1L1R0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A1L1R0" } ] } ] }, { "uniprot_canonical_ac": "A1L1R0-1", "start_pos": "540", "end_pos": "540", "site_lbl": "Thr540", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A1L1R0", "url": "https://www.uniprot.org/uniprotkb/A1L1R0" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A1L1R0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A1L1R0" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L1W4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L1W4", "url": "https://www.uniprot.org/uniprotkb/A1L1W4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 339, "chemical_mass": 38232.0, "gene_names": "rdh10a;zgc:158459", "protein_name": "Retinol dehydrogenase 10-A", "disease": [], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A1L1W4", "url": "https://www.uniprot.org/uniprotkb/A1L1W4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A1L1W4", "url": "https://www.uniprot.org/uniprotkb/A1L1W4" } ], "pmid": "" } ], "biological_process": [ { "name": "retinoic acid biosynthetic process", "id": "GO:0002138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002138", "evidence": [ { "database": "UniProtKB", "id": "A1L1W4", "url": "https://www.uniprot.org/uniprotkb/A1L1W4" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A1L1W4", "url": "https://www.uniprot.org/uniprotkb/A1L1W4" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "A1L1W4", "url": "https://www.uniprot.org/uniprotkb/A1L1W4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L209-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 367, "chemical_mass": 40720.0, "gene_names": "atxn7l3a;atxn7l3;ATXN7L3;atxn7l3;si:busm1-180g5.4;si:dz180g5.4;wu:fj12f07;zgc:136438;zgc:158566", "protein_name": "Ataxin-7-like protein 3", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "pmid": "" } ], "cellular_component": [ { "name": "DUBm complex", "id": "GO:0071819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071819", "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "A1L209", "url": "https://www.uniprot.org/uniprotkb/A1L209" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L237-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L237", "url": "https://www.uniprot.org/uniprotkb/A1L237" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 303, "chemical_mass": 33845.0, "gene_names": "endoua;endoua;endou;zgc:158628", "protein_name": "Uridylate-specific endoribonuclease A", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A1L237", "url": "https://www.uniprot.org/uniprotkb/A1L237" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A1L237", "url": "https://www.uniprot.org/uniprotkb/A1L237" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1L237", "url": "https://www.uniprot.org/uniprotkb/A1L237" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A1L237", "url": "https://www.uniprot.org/uniprotkb/A1L237" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "A1L237", "url": "https://www.uniprot.org/uniprotkb/A1L237" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1L237", "url": "https://www.uniprot.org/uniprotkb/A1L237" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1L237-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Asn28", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 28, "start_aa": "Asn", "end_pos": 28, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn28", "evidence": [ { "id": "A1L237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1L237#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A1L237-1", "start_pos": "302", "end_pos": "302", "site_lbl": "Thr302", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 302, "start_aa": "Thr", "end_pos": 302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr302", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L244-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 586, "chemical_mass": 66932.0, "gene_names": "sacm1lb;SACM1L;fc56f05;sacm1la;wu:fc56f05;zgc:158642", "protein_name": "Phosphatidylinositol-3-phosphatase SAC1-B", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane contact site", "id": "GO:0140268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140268", "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate phosphatase activity", "id": "GO:0004438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004438", "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate phosphatase activity", "id": "GO:0043812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043812", "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A1L244", "url": "https://www.uniprot.org/uniprotkb/A1L244" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L252-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 597, "chemical_mass": 65582.0, "gene_names": "ranbp9;cb457;ranbp9;zgc:158650", "protein_name": "Ran-binding protein 9", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A1L252", "url": "https://www.uniprot.org/uniprotkb/A1L252" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1L252-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Thr197", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 197, "start_aa": "Thr", "end_pos": 197, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr197", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L258-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L258", "url": "https://www.uniprot.org/uniprotkb/A1L258" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 533, "chemical_mass": 58714.0, "gene_names": "d2hgdh;d2hgdh;zgc:158661", "protein_name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "disease": [ { "disease_id": "DOID:0111351", "name": "D-2-hydroxyglutaric aciduria 1", "description": "A D-2-hydroxyglutaric aciduria that has_material_basis_in homozygous or compound heterozygous mutation in D2HGDH on 2q37.3.", "url": "https://disease-ontology.org/term/DOID:0111351", "evidence": [ { "id": "0111351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111351" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A1L258", "url": "https://www.uniprot.org/uniprotkb/A1L258" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1L258", "url": "https://www.uniprot.org/uniprotkb/A1L258" } ], "pmid": "" }, { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "A1L258", "url": "https://www.uniprot.org/uniprotkb/A1L258" } ], "pmid": "" }, { "name": "(R)-2-hydroxyglutarate dehydrogenase activity", "id": "GO:0051990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051990", "evidence": [ { "database": "UniProtKB", "id": "A1L258", "url": "https://www.uniprot.org/uniprotkb/A1L258" } ], "pmid": "" } ], "biological_process": [ { "name": "malate metabolic process", "id": "GO:0006108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006108", "evidence": [ { "database": "UniProtKB", "id": "A1L258", "url": "https://www.uniprot.org/uniprotkb/A1L258" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A1L2E4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L2E4", "url": "https://www.uniprot.org/uniprotkb/A1L2E4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 445, "chemical_mass": 49495.0, "gene_names": "mrm3b;rnmtl1b;hm:zehn2050;rnmtl1-b;rnmtl1b;zehn2050", "protein_name": "rRNA methyltransferase 3B, mitochondrial", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A1L2E4", "url": "https://www.uniprot.org/uniprotkb/A1L2E4" } ], "pmid": "" }, { "name": "rRNA (uridine-2'-O-)-methyltransferase activity", "id": "GO:0008650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008650", "evidence": [ { "database": "UniProtKB", "id": "A1L2E4", "url": "https://www.uniprot.org/uniprotkb/A1L2E4" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A1L2E4", "url": "https://www.uniprot.org/uniprotkb/A1L2E4" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A1L2E4", "url": "https://www.uniprot.org/uniprotkb/A1L2E4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1L2E4", "url": "https://www.uniprot.org/uniprotkb/A1L2E4" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A1L2E4", "url": "https://www.uniprot.org/uniprotkb/A1L2E4" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A1L2E4", "url": "https://www.uniprot.org/uniprotkb/A1L2E4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2AWE1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 199, "chemical_mass": 22061.0, "gene_names": "prdx1;NKEF-A;hm:zehl0637;prdx1;zgc:110343", "protein_name": "Peroxiredoxin-1", "disease": [ { "disease_id": "DOID:0050715", "name": "methylmalonic aciduria and homocystinuria type cblC", "description": "A methylmalonic acidemia that has_material_basis_in deficiency in synthesis of both AdoCbl and MeCbl (cblC) and is characterized by decreased levels of the coenzymes adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl), which results in decreased activity of the respective enzymes methylmalonyl-CoA mutase.", "url": "https://disease-ontology.org/term/DOID:0050715", "evidence": [ { "id": "0050715", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050715" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "pmid": "" }, { "name": "removal of superoxide radicals", "id": "GO:0019430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019430", "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "pmid": "" }, { "name": "hydrogen peroxide catabolic process", "id": "GO:0042744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042744", "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "pmid": "" }, { "name": "leukocyte activation", "id": "GO:0045321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045321", "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "pmid": "" } ], "molecular_function": [ { "name": "thioredoxin peroxidase activity", "id": "GO:0008379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008379", "evidence": [ { "database": "UniProtKB", "id": "A2AWE1", "url": "https://www.uniprot.org/uniprotkb/A2AWE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2AWU1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2AWU1", "url": "https://www.uniprot.org/uniprotkb/A2AWU1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 485, "chemical_mass": 55194.0, "gene_names": "olfm1a;olfm1a;zgc:111962;zgc:92854", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A2AWU1", "url": "https://www.uniprot.org/uniprotkb/A2AWU1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A2AWU1", "url": "https://www.uniprot.org/uniprotkb/A2AWU1" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A2AWU1", "url": "https://www.uniprot.org/uniprotkb/A2AWU1" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A2AWU1", "url": "https://www.uniprot.org/uniprotkb/A2AWU1" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A2AWU1", "url": "https://www.uniprot.org/uniprotkb/A2AWU1" } ], "pmid": "" }, { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "A2AWU1", "url": "https://www.uniprot.org/uniprotkb/A2AWU1" } ], "pmid": "" }, { "name": "positive regulation of neural retina development", "id": "GO:0061075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061075", "evidence": [ { "database": "UniProtKB", "id": "A2AWU1", "url": "https://www.uniprot.org/uniprotkb/A2AWU1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BE76-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BE76", "url": "https://www.uniprot.org/uniprotkb/A2BE76" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 265, "chemical_mass": 29877.0, "gene_names": "hapstr1;fb59e09;hapstr1b;hapstr1;si:dkey-20i6.3;tapr1;wu:fb59e09;zgc:56060;zgc:77849", "protein_name": "HUWE1-associated protein modifying stress responses", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BE76", "url": "https://www.uniprot.org/uniprotkb/A2BE76" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BE76", "url": "https://www.uniprot.org/uniprotkb/A2BE76" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "A2BE76", "url": "https://www.uniprot.org/uniprotkb/A2BE76" } ], "pmid": "" }, { "name": "regulation of cellular response to stress", "id": "GO:0080135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080135", "evidence": [ { "database": "UniProtKB", "id": "A2BE76", "url": "https://www.uniprot.org/uniprotkb/A2BE76" } ], "pmid": "" }, { "name": "negative regulation of signal transduction by p53 class mediator", "id": "GO:1901797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901797", "evidence": [ { "database": "UniProtKB", "id": "A2BE76", "url": "https://www.uniprot.org/uniprotkb/A2BE76" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2BE76-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 163, "start_aa": "Thr", "end_pos": 163, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr163", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BF66-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 356, "chemical_mass": 40976.0, "gene_names": "hormad1;hormad1;si:dkey-30o16.5;zgc:92129", "protein_name": "HORMA domain-containing protein 1", "disease": [], "biological_process": [ { "name": "meiotic recombination checkpoint signaling", "id": "GO:0051598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051598", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "regulation of homologous chromosome segregation", "id": "GO:0060629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060629", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break formation", "id": "GO:0042138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042138", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "meiotic sister chromatid cohesion", "id": "GO:0051177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051177", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" }, { "name": "synaptonemal complex", "id": "GO:0000795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000795", "evidence": [ { "database": "UniProtKB", "id": "A2BF66", "url": "https://www.uniprot.org/uniprotkb/A2BF66" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BG43-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BG43", "url": "https://www.uniprot.org/uniprotkb/A2BG43" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 209, "chemical_mass": 23949.0, "gene_names": "gltp;gltpa;gltp;si:dkey-234h16.2", "protein_name": "Glycolipid transfer protein", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A2BG43", "url": "https://www.uniprot.org/uniprotkb/A2BG43" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide transport", "id": "GO:0035627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035627", "evidence": [ { "database": "UniProtKB", "id": "A2BG43", "url": "https://www.uniprot.org/uniprotkb/A2BG43" } ], "pmid": "" }, { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "A2BG43", "url": "https://www.uniprot.org/uniprotkb/A2BG43" } ], "pmid": "" } ], "molecular_function": [ { "name": "ceramide 1-phosphate binding", "id": "GO:1902387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902387", "evidence": [ { "database": "UniProtKB", "id": "A2BG43", "url": "https://www.uniprot.org/uniprotkb/A2BG43" } ], "pmid": "" }, { "name": "ceramide 1-phosphate transfer activity", "id": "GO:1902388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902388", "evidence": [ { "database": "UniProtKB", "id": "A2BG43", "url": "https://www.uniprot.org/uniprotkb/A2BG43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BGA0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 735, "chemical_mass": 82819.0, "gene_names": "rfx4;rfx4;si:dkey-103i16.7", "protein_name": "Transcription factor RFX4", "disease": [], "biological_process": [ { "name": "ventral midline development", "id": "GO:0007418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007418", "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A2BGA0", "url": "https://www.uniprot.org/uniprotkb/A2BGA0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BGU8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 361, "chemical_mass": 40641.0, "gene_names": "septin3;sept3;septin3;si:dkey-48a12.1;zgc:110051", "protein_name": "Neuronal-specific septin-3", "disease": [], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" } ], "cellular_component": [ { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A2BGU8", "url": "https://www.uniprot.org/uniprotkb/A2BGU8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BGV1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 581, "chemical_mass": 65720.0, "gene_names": "mcoln1a;mcoln1.1;mcoln1a;mcoln1;zgc:63619", "protein_name": "", "disease": [ { "disease_id": "DOID:0060450", "name": "Lisch epithelial corneal dystrophy", "description": "An epithelial and subepithelial dystrophy that is characterized by bilateral or unilateral, gray, band-shaped, and feathery opacities that sometimes appeared in whorled patterns and that has_material_basis_in the MCOLN1 gene on Chr. 19.", "url": "https://disease-ontology.org/term/DOID:0060450", "evidence": [ { "id": "0060450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060450" } ], "weight": 0.0 }, { "disease_id": "DOID:0080490", "name": "mucolipidosis type IV", "description": "A mucolipidosis that is characterized by delayed development and vision impairment that worsens over time.", "url": "https://disease-ontology.org/term/DOID:0080490", "evidence": [ { "id": "0080490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080490" } ], "weight": 0.0 }, { "disease_id": "DOID:3343", "name": "glycoproteinosis", "description": "A mucolipidosis that is characterized by a deficiency of the enzyme alpha-N -acetyl neuraminidase (sialidase).", "url": "https://disease-ontology.org/term/DOID:3343", "evidence": [ { "id": "3343", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3343" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "NAADP-sensitive calcium-release channel activity", "id": "GO:0072345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072345", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" } ], "biological_process": [ { "name": "retina homeostasis", "id": "GO:0001895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001895", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" }, { "name": "neuromast hair cell development", "id": "GO:0035675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035675", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" }, { "name": "regulation of late endosome to lysosome transport", "id": "GO:1902822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902822", "evidence": [ { "database": "UniProtKB", "id": "A2BGV1", "url": "https://www.uniprot.org/uniprotkb/A2BGV1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2BGV1-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BHB7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BHB7", "url": "https://www.uniprot.org/uniprotkb/A2BHB7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 184, "chemical_mass": 20456.0, "gene_names": "gatc;GATC;gatc;si:rp71-1c23.3", "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial", "disease": [ { "disease_id": "DOID:0112118", "name": "combined oxidative phosphorylation deficiency 42", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the GATC gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0112118", "evidence": [ { "id": "0112118", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112118" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2BHB7", "url": "https://www.uniprot.org/uniprotkb/A2BHB7" } ], "pmid": "" }, { "name": "glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "id": "GO:0050567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050567", "evidence": [ { "database": "UniProtKB", "id": "A2BHB7", "url": "https://www.uniprot.org/uniprotkb/A2BHB7" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A2BHB7", "url": "https://www.uniprot.org/uniprotkb/A2BHB7" } ], "pmid": "" }, { "name": "glutamyl-tRNA(Gln) amidotransferase complex", "id": "GO:0030956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030956", "evidence": [ { "database": "UniProtKB", "id": "A2BHB7", "url": "https://www.uniprot.org/uniprotkb/A2BHB7" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A2BHB7", "url": "https://www.uniprot.org/uniprotkb/A2BHB7" } ], "pmid": "" }, { "name": "glutaminyl-tRNAGln biosynthesis via transamidation", "id": "GO:0070681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070681", "evidence": [ { "database": "UniProtKB", "id": "A2BHB7", "url": "https://www.uniprot.org/uniprotkb/A2BHB7" } ], "pmid": "" }, { "name": "regulation of translational fidelity", "id": "GO:0006450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006450", "evidence": [ { "database": "UniProtKB", "id": "A2BHB7", "url": "https://www.uniprot.org/uniprotkb/A2BHB7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BHJ4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 559, "chemical_mass": 63378.0, "gene_names": "cnot6l;cnot6l;si:dkey-58f10.2;zgc:111987", "protein_name": "CCR4-NOT transcription complex subunit 6-like", "disease": [ { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" }, { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "A2BHJ4", "url": "https://www.uniprot.org/uniprotkb/A2BHJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BHL9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 846, "chemical_mass": 93995.0, "gene_names": "nlgn3b;nlgn3a;nlgn3b;si:dkey-125i10.1", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 } ], "biological_process": [ { "name": "postsynaptic membrane assembly", "id": "GO:0097104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097104", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "neuron cell-cell adhesion", "id": "GO:0007158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007158", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "presynaptic membrane assembly", "id": "GO:0097105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097105", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" } ], "molecular_function": [ { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A2BHL9", "url": "https://www.uniprot.org/uniprotkb/A2BHL9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BIA3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIA3", "url": "https://www.uniprot.org/uniprotkb/A2BIA3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 958, "chemical_mass": 105232.0, "gene_names": "adamts15a;adamts15a;adamts15;si:dkey-127j5.3", "protein_name": "", "disease": [ { "disease_id": "DOID:0050646", "name": "distal arthrogryposis", "description": "A muscle tissue disease characterized by congenital joint contractures of hand and feet.", "url": "https://disease-ontology.org/term/DOID:0050646", "evidence": [ { "id": "0050646", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050646" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A2BIA3", "url": "https://www.uniprot.org/uniprotkb/A2BIA3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A2BIA3", "url": "https://www.uniprot.org/uniprotkb/A2BIA3" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A2BIA3", "url": "https://www.uniprot.org/uniprotkb/A2BIA3" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A2BIA3", "url": "https://www.uniprot.org/uniprotkb/A2BIA3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A2BIA3", "url": "https://www.uniprot.org/uniprotkb/A2BIA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BIA5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 177, "chemical_mass": 19892.0, "gene_names": "bloc1s2;bloc1s2;zgc:111974", "protein_name": "", "disease": [ { "disease_id": "DOID:3753", "name": "Hermansky-Pudlak syndrome", "description": "A syndrome characterized by oculocutaneous albinism, bleeding problems due to platelet storage pool defect, visual impairment and lysosomal accumulation of ceroid lipofuscin.", "url": "https://disease-ontology.org/term/DOID:3753", "evidence": [ { "id": "3753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3753" } ], "weight": 0.0 } ], "biological_process": [ { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" }, { "name": "positive regulation of hematopoietic stem cell differentiation", "id": "GO:1902038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902038", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" }, { "name": "positive regulation of myeloid progenitor cell differentiation", "id": "GO:1905455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905455", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" }, { "name": "negative regulation of lymphoid progenitor cell differentiation", "id": "GO:1905457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905457", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" } ], "molecular_function": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" } ], "cellular_component": [ { "name": "BORC complex", "id": "GO:0099078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099078", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" }, { "name": "BLOC-1 complex", "id": "GO:0031083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031083", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" }, { "name": "gamma-tubulin complex", "id": "GO:0000930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000930", "evidence": [ { "database": "UniProtKB", "id": "A2BIA5", "url": "https://www.uniprot.org/uniprotkb/A2BIA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BID5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BID5", "url": "https://www.uniprot.org/uniprotkb/A2BID5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 813, "chemical_mass": 91209.0, "gene_names": "veph;si:ch211-283j23.5;veph1;veph;zVeph-A", "protein_name": "Ventricular zone-expressed PH domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "evidence": [ { "database": "UniProtKB", "id": "A2BID5", "url": "https://www.uniprot.org/uniprotkb/A2BID5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2BID5", "url": "https://www.uniprot.org/uniprotkb/A2BID5" } ], "pmid": "" } ], "biological_process": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A2BID5", "url": "https://www.uniprot.org/uniprotkb/A2BID5" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A2BID5", "url": "https://www.uniprot.org/uniprotkb/A2BID5" } ], "pmid": "" }, { "name": "ear morphogenesis", "id": "GO:0042471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042471", "evidence": [ { "database": "UniProtKB", "id": "A2BID5", "url": "https://www.uniprot.org/uniprotkb/A2BID5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BIR0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 395, "chemical_mass": 45301.0, "gene_names": "sec14l8;sec14l8;si:ch211-89f7.1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" }, { "name": "GTPase activating protein binding", "id": "GO:0032794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032794", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" } ], "biological_process": [ { "name": "Wnt signaling pathway, calcium modulating pathway", "id": "GO:0007223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007223", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" }, { "name": "angioblast cell migration from lateral mesoderm to midline", "id": "GO:0035479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035479", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" }, { "name": "regulation of convergent extension involved in axis elongation", "id": "GO:1901232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901232", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" }, { "name": "positive regulation of epiboly involved in gastrulation with mouth forming second", "id": "GO:1904088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904088", "evidence": [ { "database": "UniProtKB", "id": "A2BIR0", "url": "https://www.uniprot.org/uniprotkb/A2BIR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2BIR4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIR4", "url": "https://www.uniprot.org/uniprotkb/A2BIR4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 190, "chemical_mass": 21641.0, "gene_names": "ube2l3b;UBE2L3;ube2l3b;ube2l3l;wu:fb38h03", "protein_name": "E2 ubiquitin-conjugating enzyme", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2BIR4", "url": "https://www.uniprot.org/uniprotkb/A2BIR4" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A2BIR4", "url": "https://www.uniprot.org/uniprotkb/A2BIR4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BIR4", "url": "https://www.uniprot.org/uniprotkb/A2BIR4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A2BIR4", "url": "https://www.uniprot.org/uniprotkb/A2BIR4" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A2BIR4", "url": "https://www.uniprot.org/uniprotkb/A2BIR4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CE93-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1680, "chemical_mass": 191637.0, "gene_names": "iqgap2;fc20f09;iqgap2;si:ch211-157p10.1;wu:fc20f09", "protein_name": "", "disease": [ { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" } ], "biological_process": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" }, { "name": "glomerular filtration", "id": "GO:0003094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003094", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" }, { "name": "podocyte development", "id": "GO:0072015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072015", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" }, { "name": "mitotic actomyosin contractile ring assembly actin filament organization", "id": "GO:1903479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903479", "evidence": [ { "database": "UniProtKB", "id": "A2CE93", "url": "https://www.uniprot.org/uniprotkb/A2CE93" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CEI4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 720, "chemical_mass": 80861.0, "gene_names": "nup88;ik:tdsubc_2f7;nup88;wu:fb16f10;wu:fb33e09;xx:tdsubc_2f7;zgc:112439", "protein_name": "Nucleoporin 88", "disease": [ { "disease_id": "DOID:0111379", "name": "fetal akinesia deformation sequence syndrome 4", "description": "A fetal akinesia deformation sequence that has_material_basis_in homozygous or compound heterozygous mutation in the NUP88 gene on chromosome 17p13.2.", "url": "https://disease-ontology.org/term/DOID:0111379", "evidence": [ { "id": "0111379", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111379" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2CEI4-1", "start_pos": "414", "end_pos": "414", "site_lbl": "Asp414", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "Y", "comment": "Does not rescue developmental defects in sa2206 mutants.", "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" }, { "database": "PubMed", "id": "30543681", "url": "https://glygen.org/publication/PubMed/30543681" } ] } ] }, { "uniprot_canonical_ac": "A2CEI4-1", "start_pos": "613", "end_pos": "613", "site_lbl": "Glu613", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "", "comment": "Does not rescue developmental defects in sa2206 mutants.", "evidence": [ { "database": "UniProtKB", "id": "A2CEI4", "url": "https://www.uniprot.org/uniprotkb/A2CEI4" }, { "database": "PubMed", "id": "30543681", "url": "https://glygen.org/publication/PubMed/30543681" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CEZ5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 451, "chemical_mass": 50893.0, "gene_names": "znf326;si:dkey-238n5.2;zird", "protein_name": "DBIRD complex subunit ZNF326", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" }, { "name": "DBIRD complex", "id": "GO:0044609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044609", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription elongation", "id": "GO:0032784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032784", "evidence": [ { "database": "UniProtKB", "id": "A2CEZ5", "url": "https://www.uniprot.org/uniprotkb/A2CEZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2CF49-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 324, "chemical_mass": 36825.0, "gene_names": "ptpa;fc23d07;ppp2r4;ptpa;wu:fc23d07;zgc:92766", "protein_name": "Serine/threonine-protein phosphatase 2A activator", "disease": [ { "disease_id": "DOID:0070486", "name": "Parkinson's disease 25", "description": "An early-onset Parkinson's disease characterized by mild to moderately impaired intellectual development that has_material_basis_in homozygous or compound heterozygous mutation in the PTPA gene on chromosome 9q34.11.", "url": "https://disease-ontology.org/term/DOID:0070486", "evidence": [ { "id": "0070486", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070486" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activator activity", "id": "GO:0008160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008160", "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "A2CF49", "url": "https://www.uniprot.org/uniprotkb/A2CF49" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2RRV3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 765, "chemical_mass": 85940.0, "gene_names": "patl1;CH73-251A15.1;Pat1b;fa11d04;patl1;wu:fa11d04;zgc:158239", "protein_name": "Protein PAT1 homolog 1", "disease": [], "biological_process": [ { "name": "deadenylation-dependent decapping of nuclear-transcribed mRNA", "id": "GO:0000290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000290", "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" } ], "pmid": "" }, { "name": "P-body assembly", "id": "GO:0033962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033962", "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2RRV3-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A2RRV3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2RRV3" } ] } ] }, { "uniprot_canonical_ac": "A2RRV3-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A2RRV3", "url": "https://www.uniprot.org/uniprotkb/A2RRV3" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A2RRV3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2RRV3" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2RRV9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2RRV9", "url": "https://www.uniprot.org/uniprotkb/A2RRV9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 411, "chemical_mass": 46099.0, "gene_names": "narfl;ciao3;im:7151348;narfl;zgc:158422", "protein_name": "Cytosolic Fe-S cluster assembly factor narfl", "disease": [], "biological_process": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "A2RRV9", "url": "https://www.uniprot.org/uniprotkb/A2RRV9" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "A2RRV9", "url": "https://www.uniprot.org/uniprotkb/A2RRV9" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "A2RRV9", "url": "https://www.uniprot.org/uniprotkb/A2RRV9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosolic [4Fe-4S] assembly targeting complex", "id": "GO:0097361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097361", "evidence": [ { "database": "UniProtKB", "id": "A2RRV9", "url": "https://www.uniprot.org/uniprotkb/A2RRV9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A2RRV9", "url": "https://www.uniprot.org/uniprotkb/A2RRV9" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A2RRV9", "url": "https://www.uniprot.org/uniprotkb/A2RRV9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2RV01-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2RV01", "url": "https://www.uniprot.org/uniprotkb/A2RV01" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 255, "chemical_mass": 28401.0, "gene_names": "dph6;atpbd4;dph6;si:ch1073-258j7.1;wu:fc57a01;zgc:110758", "protein_name": "Diphthine--ammonia ligase", "disease": [], "molecular_function": [ { "name": "diphthine-ammonia ligase activity", "id": "GO:0017178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017178", "evidence": [ { "database": "UniProtKB", "id": "A2RV01", "url": "https://www.uniprot.org/uniprotkb/A2RV01" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2RV01", "url": "https://www.uniprot.org/uniprotkb/A2RV01" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "A2RV01", "url": "https://www.uniprot.org/uniprotkb/A2RV01" } ], "pmid": "" } ], "biological_process": [ { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "A2RV01", "url": "https://www.uniprot.org/uniprotkb/A2RV01" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2RV06-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 624, "chemical_mass": 69904.0, "gene_names": "cfap206;C20H6orf165;C6orf165;cfap206;zgc:109719;zgc:136502", "protein_name": "Cilia- and flagella-associated protein 206", "disease": [], "cellular_component": [ { "name": "radial spoke", "id": "GO:0001534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001534", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency", "id": "GO:0003356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003356", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" }, { "name": "regulation of flagellated sperm motility", "id": "GO:1901317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901317", "evidence": [ { "database": "UniProtKB", "id": "A2RV06", "url": "https://www.uniprot.org/uniprotkb/A2RV06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2RV18-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1057, "chemical_mass": 120352.0, "gene_names": "dis3l;dis3l;zgc:158615", "protein_name": "DIS3-like exonuclease 1", "disease": [], "molecular_function": [ { "name": "exoribonuclease II activity", "id": "GO:0008859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008859", "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "A2RV18", "url": "https://www.uniprot.org/uniprotkb/A2RV18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2VCZ5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2VCZ5", "url": "https://www.uniprot.org/uniprotkb/A2VCZ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2102, "chemical_mass": 230992.0, "gene_names": "zgc:153454", "protein_name": "Mediator of RNA polymerase II transcription subunit 13-like", "disease": [ { "disease_id": "DOID:0061034", "name": "autosomal dominant intellectual developmental disorder 61", "description": "An autosomal dominant intellectual developmental disorder characterized by global developmental delay apparent in infancy with mildly impaired intellectual development, expressive speech delay, and behavioral abnormalities, including autism spectrum disorder and attention deficit-hyperactivity disorder (ADHD) that has_material_basis_in heterozygous mutation in the MED13 gene on chromosome 17q23.", "url": "https://disease-ontology.org/term/DOID:0061034", "evidence": [ { "id": "0061034", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061034" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A2VCZ5", "url": "https://www.uniprot.org/uniprotkb/A2VCZ5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A2VCZ5", "url": "https://www.uniprot.org/uniprotkb/A2VCZ5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A2VCZ5", "url": "https://www.uniprot.org/uniprotkb/A2VCZ5" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A2VCZ5", "url": "https://www.uniprot.org/uniprotkb/A2VCZ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A2VCZ5", "url": "https://www.uniprot.org/uniprotkb/A2VCZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A2VCZ5-1", "start_pos": "1023", "end_pos": "1023", "site_lbl": "Thr1023", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1023, "start_aa": "Thr", "end_pos": 1023, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1023", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A2VCZ5-1", "start_pos": "1476", "end_pos": "1476", "site_lbl": "Thr1476", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1476, "start_aa": "Thr", "end_pos": 1476, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1476", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A2VCZ5-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Thr39", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A2VCZ5-1", "start_pos": "823", "end_pos": "823", "site_lbl": "Thr823", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 823, "start_aa": "Thr", "end_pos": 823, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr823", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A2VD33-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2VD33", "url": "https://www.uniprot.org/uniprotkb/A2VD33" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 831, "chemical_mass": 92399.0, "gene_names": "mocos;MCS;MOCOS;MOS;im:7142948;zgc:110784", "protein_name": "Molybdenum cofactor sulfurase", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0070314", "name": "obstructive nephropathy", "description": "A kidney disease characterized by kidney damage and dysfunction resulting from urinary tract obstruction.", "url": "https://disease-ontology.org/term/DOID:0070314", "evidence": [ { "id": "0070314", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070314" } ], "weight": 0.0 }, { "disease_id": "DOID:0070453", "name": "xanthinuria type II", "description": "A xanthinuria characterized by deficiency of xanthine dehydrogenase and aldehyde oxidase that has_material_basis_in homozygous or compound heterozygous mutation in the MOCOS gene on chromosome 18q12.", "url": "https://disease-ontology.org/term/DOID:0070453", "evidence": [ { "id": "0070453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070453" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "molybdenum ion binding", "id": "GO:0030151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030151", "evidence": [ { "database": "UniProtKB", "id": "A2VD33", "url": "https://www.uniprot.org/uniprotkb/A2VD33" } ], "pmid": "" }, { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A2VD33", "url": "https://www.uniprot.org/uniprotkb/A2VD33" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "A2VD33", "url": "https://www.uniprot.org/uniprotkb/A2VD33" } ], "pmid": "" }, { "name": "molybdenum cofactor sulfurtransferase activity", "id": "GO:0008265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008265", "evidence": [ { "database": "UniProtKB", "id": "A2VD33", "url": "https://www.uniprot.org/uniprotkb/A2VD33" } ], "pmid": "" } ], "biological_process": [ { "name": "Mo-molybdopterin cofactor biosynthetic process", "id": "GO:0006777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006777", "evidence": [ { "database": "UniProtKB", "id": "A2VD33", "url": "https://www.uniprot.org/uniprotkb/A2VD33" } ], "pmid": "" }, { "name": "molybdopterin cofactor metabolic process", "id": "GO:0043545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043545", "evidence": [ { "database": "UniProtKB", "id": "A2VD33", "url": "https://www.uniprot.org/uniprotkb/A2VD33" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KGQ1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KGQ1", "url": "https://www.uniprot.org/uniprotkb/A3KGQ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 328, "chemical_mass": 37202.0, "gene_names": "mc5ra;mc5ar;mc5ra;mc5rb;zMC5a", "protein_name": "Melanocortin receptor 5", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A3KGQ1", "url": "https://www.uniprot.org/uniprotkb/A3KGQ1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A3KGQ1", "url": "https://www.uniprot.org/uniprotkb/A3KGQ1" } ], "pmid": "" } ], "biological_process": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A3KGQ1", "url": "https://www.uniprot.org/uniprotkb/A3KGQ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A3KGQ1", "url": "https://www.uniprot.org/uniprotkb/A3KGQ1" } ], "pmid": "" }, { "name": "melanocortin receptor activity", "id": "GO:0004977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004977", "evidence": [ { "database": "UniProtKB", "id": "A3KGQ1", "url": "https://www.uniprot.org/uniprotkb/A3KGQ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KGT9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KGT9", "url": "https://www.uniprot.org/uniprotkb/A3KGT9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 443, "chemical_mass": 50522.0, "gene_names": "agpat9l;agpat9l;si:ch211-155m12.4", "protein_name": "Glycerol-3-phosphate acyltransferase 3-like", "disease": [], "molecular_function": [ { "name": "1-acylglycerol-3-phosphate O-acyltransferase activity", "id": "GO:0003841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003841", "evidence": [ { "database": "UniProtKB", "id": "A3KGT9", "url": "https://www.uniprot.org/uniprotkb/A3KGT9" } ], "pmid": "" }, { "name": "glycerol-3-phosphate O-acyltransferase activity", "id": "GO:0004366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004366", "evidence": [ { "database": "UniProtKB", "id": "A3KGT9", "url": "https://www.uniprot.org/uniprotkb/A3KGT9" } ], "pmid": "" }, { "name": "O-acyltransferase activity", "id": "GO:0008374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008374", "evidence": [ { "database": "UniProtKB", "id": "A3KGT9", "url": "https://www.uniprot.org/uniprotkb/A3KGT9" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A3KGT9", "url": "https://www.uniprot.org/uniprotkb/A3KGT9" } ], "pmid": "" } ], "biological_process": [ { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "A3KGT9", "url": "https://www.uniprot.org/uniprotkb/A3KGT9" } ], "pmid": "" }, { "name": "CDP-diacylglycerol biosynthetic process", "id": "GO:0016024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016024", "evidence": [ { "database": "UniProtKB", "id": "A3KGT9", "url": "https://www.uniprot.org/uniprotkb/A3KGT9" } ], "pmid": "" }, { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "A3KGT9", "url": "https://www.uniprot.org/uniprotkb/A3KGT9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KMR8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KMR8", "url": "https://www.uniprot.org/uniprotkb/A3KMR8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 315, "chemical_mass": 35708.0, "gene_names": "mafaa;SMaf1;mafaa;mafa;mafl", "protein_name": "Transcription factor MafAa", "disease": [ { "disease_id": "DOID:0050524", "name": "maturity-onset diabetes of the young", "description": "A diabetes mellitus that has_material_basis_in autosomal dominant inheritance of mutations in the MODY genes impacting beta-cell function, typically occurring before 25 years of age and caused by primary insulin secretion defects.", "url": "https://disease-ontology.org/term/DOID:0050524", "evidence": [ { "id": "0050524", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050524" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A3KMR8", "url": "https://www.uniprot.org/uniprotkb/A3KMR8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A3KMR8", "url": "https://www.uniprot.org/uniprotkb/A3KMR8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A3KMR8", "url": "https://www.uniprot.org/uniprotkb/A3KMR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A3KMR8", "url": "https://www.uniprot.org/uniprotkb/A3KMR8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A3KMR8", "url": "https://www.uniprot.org/uniprotkb/A3KMR8" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A3KMR8", "url": "https://www.uniprot.org/uniprotkb/A3KMR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KNK1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 341, "chemical_mass": 40684.0, "gene_names": "tmem120aa;tmem120aa;tmem120a;zgc:162139", "protein_name": "Transmembrane protein 120A-A", "disease": [], "molecular_function": [ { "name": "coenzyme A binding", "id": "GO:0120225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120225", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" }, { "name": "monoatomic ion channel activity", "id": "GO:0005216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005216", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" } ], "biological_process": [ { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of pain", "id": "GO:0050966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050966", "evidence": [ { "database": "UniProtKB", "id": "A3KNK1", "url": "https://www.uniprot.org/uniprotkb/A3KNK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KNK7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNK7", "url": "https://www.uniprot.org/uniprotkb/A3KNK7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 114, "chemical_mass": 12786.0, "gene_names": "med11;med11", "protein_name": "Mediator of RNA polymerase II transcription subunit 11", "disease": [], "biological_process": [ { "name": "auditory behavior", "id": "GO:0031223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031223", "evidence": [ { "database": "UniProtKB", "id": "A3KNK7", "url": "https://www.uniprot.org/uniprotkb/A3KNK7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A3KNK7", "url": "https://www.uniprot.org/uniprotkb/A3KNK7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A3KNK7", "url": "https://www.uniprot.org/uniprotkb/A3KNK7" } ], "pmid": "" }, { "name": "visual behavior", "id": "GO:0007632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007632", "evidence": [ { "database": "UniProtKB", "id": "A3KNK7", "url": "https://www.uniprot.org/uniprotkb/A3KNK7" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A3KNK7", "url": "https://www.uniprot.org/uniprotkb/A3KNK7" } ], "pmid": "" } ], "cellular_component": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A3KNK7", "url": "https://www.uniprot.org/uniprotkb/A3KNK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KNL6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNL6", "url": "https://www.uniprot.org/uniprotkb/A3KNL6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 152, "chemical_mass": 17443.0, "gene_names": "ggact.3;GGACT B;GGACT C;GGACT;ggact.3;zgc:162208", "protein_name": "Gamma-glutamylaminecyclotransferase C", "disease": [], "biological_process": [ { "name": "modified amino acid catabolic process", "id": "GO:0042219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042219", "evidence": [ { "database": "UniProtKB", "id": "A3KNL6", "url": "https://www.uniprot.org/uniprotkb/A3KNL6" } ], "pmid": "" } ], "molecular_function": [ { "name": "gamma-glutamylaminecyclotransferase activity", "id": "GO:0061929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061929", "evidence": [ { "database": "UniProtKB", "id": "A3KNL6", "url": "https://www.uniprot.org/uniprotkb/A3KNL6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A3KNL6", "url": "https://www.uniprot.org/uniprotkb/A3KNL6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KNS2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNS2", "url": "https://www.uniprot.org/uniprotkb/A3KNS2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 276, "chemical_mass": 31458.0, "gene_names": "cnpy3;cnpy3;im:6892510;tnrc5", "protein_name": "Protein canopy homolog 3", "disease": [ { "disease_id": "DOID:0080432", "name": "developmental and epileptic encephalopathy 60", "description": "A developmental and epileptic encephalopathy characterized by onset of infantile spasms, seizures, or myoclonus in the first months of life, hypsarrhythmia on EEG, and severe global developmental delay that has_material_basis_in homozygous or compound heterozygous mutation in the CNPY3 gene on chromosome 6p.", "url": "https://disease-ontology.org/term/DOID:0080432", "evidence": [ { "id": "0080432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080432" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A3KNS2", "url": "https://www.uniprot.org/uniprotkb/A3KNS2" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A3KNS2", "url": "https://www.uniprot.org/uniprotkb/A3KNS2" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A3KNS2", "url": "https://www.uniprot.org/uniprotkb/A3KNS2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KNX6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNX6", "url": "https://www.uniprot.org/uniprotkb/A3KNX6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 249, "chemical_mass": 27461.0, "gene_names": "c3orf70b;c3orf70b;si:dkeyp-30d5.1;zgc:162707", "protein_name": "UPF0524 protein C3orf70 homolog B", "disease": [], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A3KNX6", "url": "https://www.uniprot.org/uniprotkb/A3KNX6" } ], "pmid": "" }, { "name": "circadian behavior", "id": "GO:0048512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048512", "evidence": [ { "database": "UniProtKB", "id": "A3KNX6", "url": "https://www.uniprot.org/uniprotkb/A3KNX6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KP37-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KP37", "url": "https://www.uniprot.org/uniprotkb/A3KP37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 321, "chemical_mass": 35928.0, "gene_names": "ndufaf5;zgc:162919", "protein_name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "disease": [ { "disease_id": "DOID:0112096", "name": "nuclear type mitochondrial complex I deficiency 16", "description": "A nuclear type mitochondrial complex I deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the NDUFAF5 gene on chromosome 20p12.1.", "url": "https://disease-ontology.org/term/DOID:0112096", "evidence": [ { "id": "0112096", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112096" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A3KP37", "url": "https://www.uniprot.org/uniprotkb/A3KP37" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A3KP37", "url": "https://www.uniprot.org/uniprotkb/A3KP37" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A3KP37", "url": "https://www.uniprot.org/uniprotkb/A3KP37" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A3KP37", "url": "https://www.uniprot.org/uniprotkb/A3KP37" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A3KP37", "url": "https://www.uniprot.org/uniprotkb/A3KP37" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "A3KP37", "url": "https://www.uniprot.org/uniprotkb/A3KP37" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KP74-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 158, "chemical_mass": 18476.0, "gene_names": "sdhaf2;pgl2;sdh5;sdhaf2;wu:fj30e04;zgc:163000", "protein_name": "Succinate dehydrogenase assembly factor 2, mitochondrial", "disease": [ { "disease_id": "DOID:0061217", "name": "pheochromocytoma/paraganglioma syndrome 2", "description": "A paraganglioma characterized by the development of neuroendocrine tumors, usually in adulthood that has material_basis_in heterozygous mutation in the SDHAF2 gene.", "url": "https://disease-ontology.org/term/DOID:0061217", "evidence": [ { "id": "0061217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061217" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "pmid": "" }, { "name": "mitochondrial electron transport, succinate to ubiquinone", "id": "GO:0006121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006121", "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "pmid": "" }, { "name": "protein-FAD linkage", "id": "GO:0018293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018293", "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex II assembly", "id": "GO:0034553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034553", "evidence": [ { "database": "UniProtKB", "id": "A3KP74", "url": "https://www.uniprot.org/uniprotkb/A3KP74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A3KP74-1", "start_pos": "121", "end_pos": "121", "site_lbl": "Thr121", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 121, "start_aa": "Thr", "end_pos": 121, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr121", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KP85-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KP85", "url": "https://www.uniprot.org/uniprotkb/A3KP85" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 258, "chemical_mass": 28950.0, "gene_names": "etfbkmt;ETFB-KMT;etfbkmt;mettl20", "protein_name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "disease": [], "biological_process": [ { "name": "negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase", "id": "GO:1904736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904736", "evidence": [ { "database": "UniProtKB", "id": "A3KP85", "url": "https://www.uniprot.org/uniprotkb/A3KP85" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A3KP85", "url": "https://www.uniprot.org/uniprotkb/A3KP85" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A3KP85", "url": "https://www.uniprot.org/uniprotkb/A3KP85" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A3KP85", "url": "https://www.uniprot.org/uniprotkb/A3KP85" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KPL8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 312, "chemical_mass": 35191.0, "gene_names": "cfdp1;cfdp1;fi15f05;gaz;si:dkey-6e12.6;wu:fi15f05;zgc:136405", "protein_name": "Craniofacial development protein 1", "disease": [], "biological_process": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "pmid": "" }, { "name": "neural retina development", "id": "GO:0003407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003407", "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "pmid": "" }, { "name": "cerebellar granule cell differentiation", "id": "GO:0021707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021707", "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "pmid": "" } ], "cellular_component": [ { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "A3KPL8", "url": "https://www.uniprot.org/uniprotkb/A3KPL8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KQ03-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 541, "chemical_mass": 62012.0, "gene_names": "mgat1b;mgat1b;si:ch211-152p11.3;zgc:153912", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" } ], "molecular_function": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" }, { "name": "alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity", "id": "GO:0003827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003827", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" }, { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" }, { "name": "regulation of sarcomere organization", "id": "GO:0060297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060297", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" }, { "name": "swimming behavior", "id": "GO:0036269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036269", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" }, { "name": "thigmotaxis", "id": "GO:0001966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001966", "evidence": [ { "database": "UniProtKB", "id": "A3KQ03", "url": "https://www.uniprot.org/uniprotkb/A3KQ03" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A3KQ03-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Thr167", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 167, "start_aa": "Thr", "end_pos": 167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr167", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KQK2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQK2", "url": "https://www.uniprot.org/uniprotkb/A3KQK2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 560, "chemical_mass": 64034.0, "gene_names": "asns;asns;zgc:56605;zgc:76901", "protein_name": "Asparagine synthetase [glutamine-hydrolyzing]", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A3KQK2", "url": "https://www.uniprot.org/uniprotkb/A3KQK2" } ], "pmid": "" }, { "name": "asparagine synthase (glutamine-hydrolyzing) activity", "id": "GO:0004066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004066", "evidence": [ { "database": "UniProtKB", "id": "A3KQK2", "url": "https://www.uniprot.org/uniprotkb/A3KQK2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A3KQK2", "url": "https://www.uniprot.org/uniprotkb/A3KQK2" } ], "pmid": "" } ], "biological_process": [ { "name": "L-asparagine biosynthetic process", "id": "GO:0070981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070981", "evidence": [ { "database": "UniProtKB", "id": "A3KQK2", "url": "https://www.uniprot.org/uniprotkb/A3KQK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3KQS4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQS4", "url": "https://www.uniprot.org/uniprotkb/A3KQS4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 520, "chemical_mass": 57366.0, "gene_names": "mindy1;fam63a;mindy1;si:ch211-210h11.5", "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-1", "disease": [], "molecular_function": [ { "name": "K48-linked polyubiquitin modification-dependent protein binding", "id": "GO:0036435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036435", "evidence": [ { "database": "UniProtKB", "id": "A3KQS4", "url": "https://www.uniprot.org/uniprotkb/A3KQS4" } ], "pmid": "" }, { "name": "cysteine-type carboxypeptidase activity", "id": "GO:0016807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016807", "evidence": [ { "database": "UniProtKB", "id": "A3KQS4", "url": "https://www.uniprot.org/uniprotkb/A3KQS4" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A3KQS4", "url": "https://www.uniprot.org/uniprotkb/A3KQS4" } ], "pmid": "" }, { "name": "K48-linked deubiquitinase activity", "id": "GO:1990380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990380", "evidence": [ { "database": "UniProtKB", "id": "A3KQS4", "url": "https://www.uniprot.org/uniprotkb/A3KQS4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A3KQS4", "url": "https://www.uniprot.org/uniprotkb/A3KQS4" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A3KQS4", "url": "https://www.uniprot.org/uniprotkb/A3KQS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A3KQS4-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Thr107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 107, "start_aa": "Thr", "end_pos": 107, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr107", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3QK15-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3QK15", "url": "https://www.uniprot.org/uniprotkb/A3QK15" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 673, "chemical_mass": 74967.0, "gene_names": "aacs;aacs;si:dkey-215k6.2;zgc:56105", "protein_name": "Acetoacetyl-CoA synthetase", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A3QK15", "url": "https://www.uniprot.org/uniprotkb/A3QK15" } ], "pmid": "" }, { "name": "acetoacetate-CoA ligase activity", "id": "GO:0030729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030729", "evidence": [ { "database": "UniProtKB", "id": "A3QK15", "url": "https://www.uniprot.org/uniprotkb/A3QK15" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A3QK15", "url": "https://www.uniprot.org/uniprotkb/A3QK15" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A3QK15", "url": "https://www.uniprot.org/uniprotkb/A3QK15" } ], "pmid": "" }, { "name": "positive regulation of insulin secretion", "id": "GO:0032024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032024", "evidence": [ { "database": "UniProtKB", "id": "A3QK15", "url": "https://www.uniprot.org/uniprotkb/A3QK15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3QK16-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 331, "chemical_mass": 36466.0, "gene_names": "erlin2;erlin2;si:dkey-204l11.2", "protein_name": "Erlin-2", "disease": [], "biological_process": [ { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "pmid": "" }, { "name": "negative regulation of fatty acid biosynthetic process", "id": "GO:0045717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045717", "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "pmid": "" }, { "name": "negative regulation of cholesterol biosynthetic process", "id": "GO:0045541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045541", "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "pmid": "" }, { "name": "SREBP signaling pathway", "id": "GO:0032933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032933", "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A3QK16", "url": "https://www.uniprot.org/uniprotkb/A3QK16" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A3QK16-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Asn105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 105, "start_aa": "Asn", "end_pos": 105, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn105", "evidence": [ { "id": "A3QK16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3QK16#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3QK20-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3QK20", "url": "https://www.uniprot.org/uniprotkb/A3QK20" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 497, "chemical_mass": 55124.0, "gene_names": "ptger4b;ptger4b;si:dkey-204l11.6", "protein_name": "Prostaglandin E2 receptor EP4 subtype", "disease": [ { "disease_id": "DOID:0080822", "name": "aspirin-induced respiratory disease", "description": "An intrinsic asthma that is characterized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs.", "url": "https://disease-ontology.org/term/DOID:0080822", "evidence": [ { "id": "0080822", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080822" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:3627", "name": "aortic aneurysm", "description": "An aortic disease that is characterized by an enlargement (dilation) of the aorta to greater than 1.5 times normal size.", "url": "https://disease-ontology.org/term/DOID:3627", "evidence": [ { "id": "3627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3627" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A3QK20", "url": "https://www.uniprot.org/uniprotkb/A3QK20" } ], "pmid": "" } ], "biological_process": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A3QK20", "url": "https://www.uniprot.org/uniprotkb/A3QK20" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A3QK20", "url": "https://www.uniprot.org/uniprotkb/A3QK20" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "A3QK20", "url": "https://www.uniprot.org/uniprotkb/A3QK20" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A3QK20", "url": "https://www.uniprot.org/uniprotkb/A3QK20" } ], "pmid": "" }, { "name": "cellular response to prostaglandin E stimulus", "id": "GO:0071380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071380", "evidence": [ { "database": "UniProtKB", "id": "A3QK20", "url": "https://www.uniprot.org/uniprotkb/A3QK20" } ], "pmid": "" } ], "molecular_function": [ { "name": "prostaglandin E receptor activity", "id": "GO:0004957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004957", "evidence": [ { "database": "UniProtKB", "id": "A3QK20", "url": "https://www.uniprot.org/uniprotkb/A3QK20" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A3RK75-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3RK75", "url": "https://www.uniprot.org/uniprotkb/A3RK75" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 629, "chemical_mass": 68539.0, "gene_names": "foxo1b;foxO1a.2;foxo1a.2;foxo1b", "protein_name": "Forkhead box protein O1-B", "disease": [ { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:4051", "name": "alveolar rhabdomyosarcoma", "description": "", "url": "https://disease-ontology.org/term/DOID:4051", "evidence": [ { "id": "4051", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4051" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A3RK75", "url": "https://www.uniprot.org/uniprotkb/A3RK75" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A3RK75", "url": "https://www.uniprot.org/uniprotkb/A3RK75" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A3RK75", "url": "https://www.uniprot.org/uniprotkb/A3RK75" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A3RK75", "url": "https://www.uniprot.org/uniprotkb/A3RK75" } ], "pmid": "" }, { "name": "lymph vessel development", "id": "GO:0001945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001945", "evidence": [ { "database": "UniProtKB", "id": "A3RK75", "url": "https://www.uniprot.org/uniprotkb/A3RK75" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A3RK75", "url": "https://www.uniprot.org/uniprotkb/A3RK75" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A3RK75", "url": "https://www.uniprot.org/uniprotkb/A3RK75" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IG19-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IG19", "url": "https://www.uniprot.org/uniprotkb/A4IG19" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 843, "chemical_mass": 97428.0, "gene_names": "pygb;pygb", "protein_name": "Alpha-1,4 glucan phosphorylase", "disease": [ { "disease_id": "DOID:2747", "name": "glycogen storage disease", "description": "A glycogen metabolism disorder that has_material_basis_in enzymes deficiencies necessary in the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types.", "url": "https://disease-ontology.org/term/DOID:2747", "evidence": [ { "id": "2747", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2747" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4IG19", "url": "https://www.uniprot.org/uniprotkb/A4IG19" } ], "pmid": "" } ], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A4IG19", "url": "https://www.uniprot.org/uniprotkb/A4IG19" } ], "pmid": "" }, { "name": "glycogen phosphorylase activity", "id": "GO:0008184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008184", "evidence": [ { "database": "UniProtKB", "id": "A4IG19", "url": "https://www.uniprot.org/uniprotkb/A4IG19" } ], "pmid": "" } ], "biological_process": [ { "name": "glycogen catabolic process", "id": "GO:0005980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005980", "evidence": [ { "database": "UniProtKB", "id": "A4IG19", "url": "https://www.uniprot.org/uniprotkb/A4IG19" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IG53-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IG53", "url": "https://www.uniprot.org/uniprotkb/A4IG53" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 264, "chemical_mass": 29872.0, "gene_names": "comtb;comtb;si:dkey-13a21.15;zK13A21.15;zgc:162236", "protein_name": "Catechol O-methyltransferase B", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10933", "name": "obsessive-compulsive disorder", "description": "An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions).", "url": "https://disease-ontology.org/term/DOID:10933", "evidence": [ { "id": "10933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10933" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11612", "name": "polycystic ovary syndrome", "description": "An ovarian dysfunction that is characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight.", "url": "https://disease-ontology.org/term/DOID:11612", "evidence": [ { "id": "11612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11612" } ], "weight": 0.0 }, { "disease_id": "DOID:12129", "name": "bulimia nervosa", "description": "An eating disorder characterized by the restraining of food intake for a period of time followed by an over intake or binging period that results in feelings of guilt and low self-esteem.", "url": "https://disease-ontology.org/term/DOID:12129", "evidence": [ { "id": "12129", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12129" } ], "weight": 0.0 }, { "disease_id": "DOID:12306", "name": "vitiligo", "description": "An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes.", "url": "https://disease-ontology.org/term/DOID:12306", "evidence": [ { "id": "12306", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12306" } ], "weight": 0.0 }, { "disease_id": "DOID:12399", "name": "pathological gambling", "description": "An impulse control disorder that involves the uncontrollable impulse to gamble, irrespective of the interference the behaviour has on the individual's life.", "url": "https://disease-ontology.org/term/DOID:12399", "evidence": [ { "id": "12399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12399" } ], "weight": 0.0 }, { "disease_id": "DOID:12401", "name": "intermittent explosive disorder", "description": "An impulse control disorder that involves the episodic inability to control violent impulses with a disproportionate degree of aggressiveness.", "url": "https://disease-ontology.org/term/DOID:12401", "evidence": [ { "id": "12401", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12401" } ], "weight": 0.0 }, { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:13078", "name": "eumycotic mycetoma", "description": "A dermatomycosis that effects skin and subcutaneous tissue located in foot, located in trunk, located in buttocks, located in eyelids, located in lacrimal glands, located in paranasal sinuses, located in mandible, located in scalp, located in neck, located in perineum, or located in testes and has symptom sinus discharge and results in formation of nodules.", "url": "https://disease-ontology.org/term/DOID:13078", "evidence": [ { "id": "13078", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13078" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1561", "name": "cognitive disorder", "description": "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.", "url": "https://disease-ontology.org/term/DOID:1561", "evidence": [ { "id": "1561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1561" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1849", "name": "cannabis dependence", "description": "A drug dependence that involves the continued use of cannabis despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:1849", "evidence": [ { "id": "1849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1849" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:2560", "name": "morphine dependence", "description": "An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2560", "evidence": [ { "id": "2560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2560" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4676", "name": "uremia", "description": "", "url": "https://disease-ontology.org/term/DOID:4676", "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:631", "name": "fibromyalgia", "description": "A syndrome that is is characterized by chronic widespread musculoskeletal pain, fatigue, sleep disturbances, cognitive dysfunction and depression.", "url": "https://disease-ontology.org/term/DOID:631", "evidence": [ { "id": "631", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:631" } ], "weight": 0.0 }, { "disease_id": "DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:670", "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:9505", "name": "cannabis abuse", "description": "A substance abuse that involves the recurring use of cannabis despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:9505", "evidence": [ { "id": "9505", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9505" } ], "weight": 0.0 }, { "disease_id": "DOID:9828", "name": "neonatal abstinence syndrome", "description": "A withdrawal disorder that is characterized by a group of problems that occur in a newborn who was exposed to addictive illegal or prescription drugs while in the mother's womb or postnatally following the discontinuance of drug treatment.", "url": "https://disease-ontology.org/term/DOID:9828", "evidence": [ { "id": "9828", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9828" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9974", "name": "drug dependence", "description": "A substance dependence that involves the continued use of drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9974", "evidence": [ { "id": "9974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9974" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A4IG53", "url": "https://www.uniprot.org/uniprotkb/A4IG53" } ], "pmid": "" }, { "name": "catechol O-methyltransferase activity", "id": "GO:0016206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016206", "evidence": [ { "database": "UniProtKB", "id": "A4IG53", "url": "https://www.uniprot.org/uniprotkb/A4IG53" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A4IG53", "url": "https://www.uniprot.org/uniprotkb/A4IG53" } ], "pmid": "" } ], "biological_process": [ { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A4IG53", "url": "https://www.uniprot.org/uniprotkb/A4IG53" } ], "pmid": "" }, { "name": "dopamine metabolic process", "id": "GO:0042417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042417", "evidence": [ { "database": "UniProtKB", "id": "A4IG53", "url": "https://www.uniprot.org/uniprotkb/A4IG53" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A4IG53", "url": "https://www.uniprot.org/uniprotkb/A4IG53" } ], "pmid": "" }, { "name": "catecholamine catabolic process", "id": "GO:0042424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042424", "evidence": [ { "database": "UniProtKB", "id": "A4IG53", "url": "https://www.uniprot.org/uniprotkb/A4IG53" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A4IG53-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Asn31", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 31, "start_aa": "Asn", "end_pos": 31, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn31", "evidence": [ { "id": "A4IG53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IG53#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IG55-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IG55", "url": "https://www.uniprot.org/uniprotkb/A4IG55" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 520, "chemical_mass": 58751.0, "gene_names": "plekho1a;ckip-1;ckip;plekho1a;plekho1;si:dkey-200h23.2", "protein_name": "Pleckstrin homology domain-containing family O member 1-A", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A4IG55", "url": "https://www.uniprot.org/uniprotkb/A4IG55" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4IG55", "url": "https://www.uniprot.org/uniprotkb/A4IG55" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A4IG55", "url": "https://www.uniprot.org/uniprotkb/A4IG55" } ], "pmid": "" }, { "name": "muscle cell projection membrane", "id": "GO:0036195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036195", "evidence": [ { "database": "UniProtKB", "id": "A4IG55", "url": "https://www.uniprot.org/uniprotkb/A4IG55" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A4IG55", "url": "https://www.uniprot.org/uniprotkb/A4IG55" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of myoblast fusion", "id": "GO:1901739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901739", "evidence": [ { "database": "UniProtKB", "id": "A4IG55", "url": "https://www.uniprot.org/uniprotkb/A4IG55" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IG61-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IG61", "url": "https://www.uniprot.org/uniprotkb/A4IG61" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 468, "chemical_mass": 52101.0, "gene_names": "mief1;im:7156228;mid51;mief1;smcr7a;smcr7l;zgc:162279", "protein_name": "Mitochondrial dynamics protein MID51", "disease": [ { "disease_id": "DOID:5723", "name": "optic atrophy", "description": "An optic nerve disease that is characterized the death of the retinal ganglion cell axons that comprise the optic nerve.", "url": "https://disease-ontology.org/term/DOID:5723", "evidence": [ { "id": "5723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5723" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of mitochondrial fusion", "id": "GO:0010636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010636", "evidence": [ { "database": "UniProtKB", "id": "A4IG61", "url": "https://www.uniprot.org/uniprotkb/A4IG61" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A4IG61", "url": "https://www.uniprot.org/uniprotkb/A4IG61" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "A4IG61", "url": "https://www.uniprot.org/uniprotkb/A4IG61" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "A4IG61", "url": "https://www.uniprot.org/uniprotkb/A4IG61" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A4IG61", "url": "https://www.uniprot.org/uniprotkb/A4IG61" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A4IG61", "url": "https://www.uniprot.org/uniprotkb/A4IG61" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A4IG61", "url": "https://www.uniprot.org/uniprotkb/A4IG61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IG72-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IG72", "url": "https://www.uniprot.org/uniprotkb/A4IG72" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 863, "chemical_mass": 97048.0, "gene_names": "tgfbrap1;tgfbrap1;zgc:162302", "protein_name": "Transforming growth factor-beta receptor-associated protein 1 homolog", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4IG72", "url": "https://www.uniprot.org/uniprotkb/A4IG72" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A4IG72", "url": "https://www.uniprot.org/uniprotkb/A4IG72" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A4IG72", "url": "https://www.uniprot.org/uniprotkb/A4IG72" } ], "pmid": "" }, { "name": "CORVET complex", "id": "GO:0033263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033263", "evidence": [ { "database": "UniProtKB", "id": "A4IG72", "url": "https://www.uniprot.org/uniprotkb/A4IG72" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A4IG72", "url": "https://www.uniprot.org/uniprotkb/A4IG72" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A4IG72", "url": "https://www.uniprot.org/uniprotkb/A4IG72" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IGD2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IGD2", "url": "https://www.uniprot.org/uniprotkb/A4IGD2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 282, "chemical_mass": 32270.0, "gene_names": "nat8l;nat8l;sb:cb562;zgc:162648", "protein_name": "N-acetylaspartate synthetase", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A4IGD2", "url": "https://www.uniprot.org/uniprotkb/A4IGD2" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A4IGD2", "url": "https://www.uniprot.org/uniprotkb/A4IGD2" } ], "pmid": "" }, { "name": "intracellular membrane-bounded organelle", "id": "GO:0043231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", "evidence": [ { "database": "UniProtKB", "id": "A4IGD2", "url": "https://www.uniprot.org/uniprotkb/A4IGD2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A4IGD2", "url": "https://www.uniprot.org/uniprotkb/A4IGD2" } ], "pmid": "" } ], "molecular_function": [ { "name": "L-aspartate N-acetyltransferase activity", "id": "GO:0017188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017188", "evidence": [ { "database": "UniProtKB", "id": "A4IGD2", "url": "https://www.uniprot.org/uniprotkb/A4IGD2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IGH2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IGH2", "url": "https://www.uniprot.org/uniprotkb/A4IGH2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 444, "chemical_mass": 50036.0, "gene_names": "rsad1;rsad1;wu:fc10b04;wu:fv45h05", "protein_name": "Radical S-adenosyl methionine domain-containing protein 1, mitochondrial", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4IGH2", "url": "https://www.uniprot.org/uniprotkb/A4IGH2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A4IGH2", "url": "https://www.uniprot.org/uniprotkb/A4IGH2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A4IGH2", "url": "https://www.uniprot.org/uniprotkb/A4IGH2" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A4IGH2", "url": "https://www.uniprot.org/uniprotkb/A4IGH2" } ], "pmid": "" }, { "name": "coproporphyrinogen oxidase activity", "id": "GO:0004109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004109", "evidence": [ { "database": "UniProtKB", "id": "A4IGH2", "url": "https://www.uniprot.org/uniprotkb/A4IGH2" } ], "pmid": "" } ], "biological_process": [ { "name": "porphyrin-containing compound biosynthetic process", "id": "GO:0006779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006779", "evidence": [ { "database": "UniProtKB", "id": "A4IGH2", "url": "https://www.uniprot.org/uniprotkb/A4IGH2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A4IGH2-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Thr139", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 139, "start_aa": "Thr", "end_pos": 139, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr139", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4IGH4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4IGH4", "url": "https://www.uniprot.org/uniprotkb/A4IGH4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 413, "chemical_mass": 46240.0, "gene_names": "wdr4;im:6900357;si:ch211-140m22.6;wdr4", "protein_name": "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wdr4", "disease": [ { "disease_id": "DOID:0050569", "name": "Seckel syndrome", "description": "A syndrome characterized by intrauterine growth retardation and postnatal dwarfism with microcephaly and intellectual disability.", "url": "https://disease-ontology.org/term/DOID:0050569", "evidence": [ { "id": "0050569", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050569" } ], "weight": 0.0 }, { "disease_id": "DOID:0080694", "name": "Galloway-Mowat syndrome", "description": "A syndrome that is characterized by developmental delay, progressive microcephaly, cerebral and cerebellar atrophy with extrapyramidal involvement, and optic atrophy.", "url": "https://disease-ontology.org/term/DOID:0080694", "evidence": [ { "id": "0080694", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080694" } ], "weight": 0.0 }, { "disease_id": "DOID:0081051", "name": "microcephaly, growth deficiency, seizures, and brain malformations", "description": "A syndrome that is characterized by intrauterine growth retardation, postnatal growth deficiency with severe microcephaly, and poor or absent psychomotor development, and that has_material_basis_in homozygous mutation in the WDR4 gene on chromosome 21q22.", "url": "https://disease-ontology.org/term/DOID:0081051", "evidence": [ { "id": "0081051", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081051" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A4IGH4", "url": "https://www.uniprot.org/uniprotkb/A4IGH4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A4IGH4", "url": "https://www.uniprot.org/uniprotkb/A4IGH4" } ], "pmid": "" }, { "name": "tRNA methyltransferase complex", "id": "GO:0043527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043527", "evidence": [ { "database": "UniProtKB", "id": "A4IGH4", "url": "https://www.uniprot.org/uniprotkb/A4IGH4" } ], "pmid": "" }, { "name": "tRNA (m7G46) methyltransferase complex", "id": "GO:0106143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106143", "evidence": [ { "database": "UniProtKB", "id": "A4IGH4", "url": "https://www.uniprot.org/uniprotkb/A4IGH4" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "A4IGH4", "url": "https://www.uniprot.org/uniprotkb/A4IGH4" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "A4IGH4", "url": "https://www.uniprot.org/uniprotkb/A4IGH4" } ], "pmid": "" }, { "name": "tRNA (guanine-N7)-methylation", "id": "GO:0106004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106004", "evidence": [ { "database": "UniProtKB", "id": "A4IGH4", "url": "https://www.uniprot.org/uniprotkb/A4IGH4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4QN59-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4QN59", "url": "https://www.uniprot.org/uniprotkb/A4QN59" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 498, "chemical_mass": 55152.0, "gene_names": "dph2;dph2;id:ibd5058;zgc:162269", "protein_name": "2-(3-amino-3-carboxypropyl)histidine synthase subunit 2", "disease": [ { "disease_id": "DOID:0070476", "name": "diphthamide deficiency syndrome", "description": "An inherited metabolic disorder characterized by global developmental delay, short stature, dysmorphic craniofacial features, and sparse hair that has_material_basis_in deficient diphthamidylation of the eukaryotic translation Elongation Factor 2 protein (gene: EEF2).", "url": "https://disease-ontology.org/term/DOID:0070476", "evidence": [ { "id": "0070476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070476" } ], "weight": 0.0 }, { "disease_id": "DOID:0070478", "name": "diphthamide deficiency syndrome 2", "description": "A diphthamide deficiency syndrome that has_material_basis_in homozygous or compound heterozygous mutations in the DPH2 gene on chromosome 1p34.1.", "url": "https://disease-ontology.org/term/DOID:0070478", "evidence": [ { "id": "0070478", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070478" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A4QN59", "url": "https://www.uniprot.org/uniprotkb/A4QN59" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A4QN59", "url": "https://www.uniprot.org/uniprotkb/A4QN59" } ], "pmid": "" }, { "name": "2-(3-amino-3-carboxypropyl)histidine synthase activity", "id": "GO:0090560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090560", "evidence": [ { "database": "UniProtKB", "id": "A4QN59", "url": "https://www.uniprot.org/uniprotkb/A4QN59" } ], "pmid": "" } ], "biological_process": [ { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "A4QN59", "url": "https://www.uniprot.org/uniprotkb/A4QN59" } ], "pmid": "" } ], "cellular_component": [ { "name": "2-(3-amino-3-carboxypropyl)histidine synthase complex", "id": "GO:0120513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120513", "evidence": [ { "database": "UniProtKB", "id": "A4QN59", "url": "https://www.uniprot.org/uniprotkb/A4QN59" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4QNZ7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4QNZ7", "url": "https://www.uniprot.org/uniprotkb/A4QNZ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 317, "chemical_mass": 34422.0, "gene_names": "p33monox;sb:eu284;p33monox;zgc:123105", "protein_name": "Putative monooxygenase p33MONOX", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4QNZ7", "url": "https://www.uniprot.org/uniprotkb/A4QNZ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A4QNZ7", "url": "https://www.uniprot.org/uniprotkb/A4QNZ7" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "A4QNZ7", "url": "https://www.uniprot.org/uniprotkb/A4QNZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A4QNZ7-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Thr173", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 173, "start_aa": "Thr", "end_pos": 173, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr173", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A4QNZ7-1", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A4QNZ7", "url": "https://www.uniprot.org/uniprotkb/A4QNZ7" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A4QNZ7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A4QNZ7" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4QP16-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4QP16", "url": "https://www.uniprot.org/uniprotkb/A4QP16" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 962, "chemical_mass": 108104.0, "gene_names": "adnp2a;adnp2a;adnp2;im:6912290;wu:fc45g06;znf508", "protein_name": "Activity-dependent neuroprotective protein 2a", "disease": [], "biological_process": [ { "name": "erythrocyte maturation", "id": "GO:0043249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043249", "evidence": [ { "database": "UniProtKB", "id": "A4QP16", "url": "https://www.uniprot.org/uniprotkb/A4QP16" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A4QP16", "url": "https://www.uniprot.org/uniprotkb/A4QP16" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A4QP16", "url": "https://www.uniprot.org/uniprotkb/A4QP16" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A4QP16", "url": "https://www.uniprot.org/uniprotkb/A4QP16" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A4QP16", "url": "https://www.uniprot.org/uniprotkb/A4QP16" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A4QP16", "url": "https://www.uniprot.org/uniprotkb/A4QP16" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A4QP16-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Thr492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 492, "start_aa": "Thr", "end_pos": 492, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr492", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4QP72-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 534, "chemical_mass": 60002.0, "gene_names": "fam83d;fam83d;im:7149534;sack1d;zgc:162965", "protein_name": "Protein FAM83D", "disease": [], "biological_process": [ { "name": "metaphase chromosome alignment", "id": "GO:0051310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051310", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "regulation of ERK1 and ERK2 cascade", "id": "GO:0070372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070372", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "regulation of TOR signaling", "id": "GO:0032006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032006", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "positive regulation of cell cycle G1/S phase transition", "id": "GO:1902808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902808", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "protein localization to mitotic spindle", "id": "GO:1902480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902480", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A4QP72", "url": "https://www.uniprot.org/uniprotkb/A4QP72" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A4QP72-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Thr128", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 128, "start_aa": "Thr", "end_pos": 128, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr128", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4QP73-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4QP73", "url": "https://www.uniprot.org/uniprotkb/A4QP73" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 403, "chemical_mass": 45132.0, "gene_names": "ttc19;si:dkey-270k22.4", "protein_name": "Tetratricopeptide repeat protein 19, mitochondrial", "disease": [ { "disease_id": "DOID:0060351", "name": "mitochondrial complex III deficiency nuclear type 2", "description": "A mitochondrial metabolism disease characterized by motor disability, with ataxia, apraxia, dystonia, and dysarthria, associated with necrotic lesions throughout the brain and has_material_basis_in mutation in the TTC19 gene on chromosome 17. It has an autosomal recessive inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060351", "evidence": [ { "id": "0060351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060351" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A4QP73", "url": "https://www.uniprot.org/uniprotkb/A4QP73" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A4QP73", "url": "https://www.uniprot.org/uniprotkb/A4QP73" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A4QP73", "url": "https://www.uniprot.org/uniprotkb/A4QP73" } ], "pmid": "" }, { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "A4QP73", "url": "https://www.uniprot.org/uniprotkb/A4QP73" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "A4QP73", "url": "https://www.uniprot.org/uniprotkb/A4QP73" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4QP75-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4QP75", "url": "https://www.uniprot.org/uniprotkb/A4QP75" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 480, "chemical_mass": 53895.0, "gene_names": "trmt2b;im:7160396;si:dkeyp-115d2.4;trmt2b;wu:fc49d02;zgc:162982", "protein_name": "tRNA (uracil-5-)-methyltransferase homolog B", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A4QP75", "url": "https://www.uniprot.org/uniprotkb/A4QP75" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A4QP75", "url": "https://www.uniprot.org/uniprotkb/A4QP75" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent", "id": "GO:0030697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030697", "evidence": [ { "database": "UniProtKB", "id": "A4QP75", "url": "https://www.uniprot.org/uniprotkb/A4QP75" } ], "pmid": "" }, { "name": "rRNA (uridine-C5-)-methyltransferase activity", "id": "GO:0070041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070041", "evidence": [ { "database": "UniProtKB", "id": "A4QP75", "url": "https://www.uniprot.org/uniprotkb/A4QP75" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4QP81-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4QP81", "url": "https://www.uniprot.org/uniprotkb/A4QP81" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 573, "chemical_mass": 61284.0, "gene_names": "frrs1;zgc:163022;fj05g07;frrs1;wu:fj05g07;zgc:163022", "protein_name": "Ferric reductase 1", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A4QP81", "url": "https://www.uniprot.org/uniprotkb/A4QP81" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A4QP81", "url": "https://www.uniprot.org/uniprotkb/A4QP81" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on metal ions", "id": "GO:0016722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016722", "evidence": [ { "database": "UniProtKB", "id": "A4QP81", "url": "https://www.uniprot.org/uniprotkb/A4QP81" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A4QP81-1", "start_pos": "186", "end_pos": "186", "site_lbl": "Thr186", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 186, "start_aa": "Thr", "end_pos": 186, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr186", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A4QP81-1", "start_pos": "286", "end_pos": "286", "site_lbl": "Asn286", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 286, "start_aa": "Asn", "end_pos": 286, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn286", "evidence": [ { "id": "A4QP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4QP81#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A4QP81-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Asn300", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 300, "start_aa": "Asn", "end_pos": 300, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn300", "evidence": [ { "id": "A4QP81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4QP81#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4VCH0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 586, "chemical_mass": 67120.0, "gene_names": "sacm1la;sacm1la;sacm1lb;si:ch211-222e23.8", "protein_name": "Phosphatidylinositol-3-phosphatase SAC1-A", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane contact site", "id": "GO:0140268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140268", "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3-phosphate phosphatase activity", "id": "GO:0004438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004438", "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate phosphatase activity", "id": "GO:0043812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043812", "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A4VCH0", "url": "https://www.uniprot.org/uniprotkb/A4VCH0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A4ZNR5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4ZNR5", "url": "https://www.uniprot.org/uniprotkb/A4ZNR5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 409, "chemical_mass": 47136.0, "gene_names": "nkd2l;nkd2a;nkd2b;nkd2l;nkd2", "protein_name": "Protein naked cuticle homolog 2-like", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR5", "url": "https://www.uniprot.org/uniprotkb/A4ZNR5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR5", "url": "https://www.uniprot.org/uniprotkb/A4ZNR5" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR5", "url": "https://www.uniprot.org/uniprotkb/A4ZNR5" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR5", "url": "https://www.uniprot.org/uniprotkb/A4ZNR5" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR5", "url": "https://www.uniprot.org/uniprotkb/A4ZNR5" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A4ZNR5", "url": "https://www.uniprot.org/uniprotkb/A4ZNR5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5D6R3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5D6R3", "url": "https://www.uniprot.org/uniprotkb/A5D6R3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 784, "chemical_mass": 89381.0, "gene_names": "plcd3a;plcd3a;zgc:158396", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "id": "GO:0004435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004435", "evidence": [ { "database": "UniProtKB", "id": "A5D6R3", "url": "https://www.uniprot.org/uniprotkb/A5D6R3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A5D6R3", "url": "https://www.uniprot.org/uniprotkb/A5D6R3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5D6R3", "url": "https://www.uniprot.org/uniprotkb/A5D6R3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A5D6R3", "url": "https://www.uniprot.org/uniprotkb/A5D6R3" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A5D6R3", "url": "https://www.uniprot.org/uniprotkb/A5D6R3" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A5D6R3", "url": "https://www.uniprot.org/uniprotkb/A5D6R3" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A5D6R3", "url": "https://www.uniprot.org/uniprotkb/A5D6R3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5D6U8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5D6U8", "url": "https://www.uniprot.org/uniprotkb/A5D6U8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 443, "chemical_mass": 50745.0, "gene_names": "acp7;papl;zgc:162913", "protein_name": "Acid phosphatase type 7", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A5D6U8", "url": "https://www.uniprot.org/uniprotkb/A5D6U8" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A5D6U8", "url": "https://www.uniprot.org/uniprotkb/A5D6U8" } ], "pmid": "" }, { "name": "acid phosphatase activity", "id": "GO:0003993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003993", "evidence": [ { "database": "UniProtKB", "id": "A5D6U8", "url": "https://www.uniprot.org/uniprotkb/A5D6U8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5D6U8-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Asn126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 126, "start_aa": "Asn", "end_pos": 126, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn126", "evidence": [ { "id": "A5D6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D6U8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5D6U8-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Asn210", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 210, "start_aa": "Asn", "end_pos": 210, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn210", "evidence": [ { "id": "A5D6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D6U8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5D6U8-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Asn313", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 313, "start_aa": "Asn", "end_pos": 313, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn313", "evidence": [ { "id": "A5D6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D6U8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5D6U8-1", "start_pos": "355", "end_pos": "355", "site_lbl": "Asn355", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 355, "start_aa": "Asn", "end_pos": 355, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn355", "evidence": [ { "id": "A5D6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D6U8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5D6U8-1", "start_pos": "409", "end_pos": "409", "site_lbl": "Asn409", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 409, "start_aa": "Asn", "end_pos": 409, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn409", "evidence": [ { "id": "A5D6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D6U8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5D6U8-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Asn53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "A5D6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D6U8#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5D6U8-1", "start_pos": "76", "end_pos": "76", "site_lbl": "Asn76", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 76, "start_aa": "Asn", "end_pos": 76, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn76", "evidence": [ { "id": "A5D6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D6U8#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5D8S8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5D8S8", "url": "https://www.uniprot.org/uniprotkb/A5D8S8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 319, "chemical_mass": 36219.0, "gene_names": "hexim1;fd44h02;hexim1;hexim;wu:fd44h02;zgc:162976", "protein_name": "Protein HEXIM1", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A5D8S8", "url": "https://www.uniprot.org/uniprotkb/A5D8S8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A5D8S8", "url": "https://www.uniprot.org/uniprotkb/A5D8S8" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A5D8S8", "url": "https://www.uniprot.org/uniprotkb/A5D8S8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A5D8S8", "url": "https://www.uniprot.org/uniprotkb/A5D8S8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5D8S8", "url": "https://www.uniprot.org/uniprotkb/A5D8S8" } ], "pmid": "" } ], "molecular_function": [ { "name": "7SK snRNA binding", "id": "GO:0097322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097322", "evidence": [ { "database": "UniProtKB", "id": "A5D8S8", "url": "https://www.uniprot.org/uniprotkb/A5D8S8" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase inhibitor activity", "id": "GO:0004861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004861", "evidence": [ { "database": "UniProtKB", "id": "A5D8S8", "url": "https://www.uniprot.org/uniprotkb/A5D8S8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5JV83-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5JV83", "url": "https://www.uniprot.org/uniprotkb/A5JV83" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 205, "chemical_mass": 23823.0, "gene_names": "hspb11;cb02d06;hspb11;hspb9l;mg:cb02d06", "protein_name": "Heat shock protein beta-11", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5JV83", "url": "https://www.uniprot.org/uniprotkb/A5JV83" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5JV83", "url": "https://www.uniprot.org/uniprotkb/A5JV83" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A5JV83", "url": "https://www.uniprot.org/uniprotkb/A5JV83" } ], "pmid": "" } ], "biological_process": [ { "name": "response to heat", "id": "GO:0009408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009408", "evidence": [ { "database": "UniProtKB", "id": "A5JV83", "url": "https://www.uniprot.org/uniprotkb/A5JV83" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "A5JV83", "url": "https://www.uniprot.org/uniprotkb/A5JV83" } ], "pmid": "" }, { "name": "myosin filament organization", "id": "GO:0031033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031033", "evidence": [ { "database": "UniProtKB", "id": "A5JV83", "url": "https://www.uniprot.org/uniprotkb/A5JV83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PF62-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PF62", "url": "https://www.uniprot.org/uniprotkb/A5PF62" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 675, "chemical_mass": 76625.0, "gene_names": "themis;ch211-205n18.3;im:7138580", "protein_name": "Protein THEMIS", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative T cell selection", "id": "GO:0043383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043383", "evidence": [ { "database": "UniProtKB", "id": "A5PF62", "url": "https://www.uniprot.org/uniprotkb/A5PF62" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A5PF62", "url": "https://www.uniprot.org/uniprotkb/A5PF62" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A5PF62", "url": "https://www.uniprot.org/uniprotkb/A5PF62" } ], "pmid": "" }, { "name": "positive T cell selection", "id": "GO:0043368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043368", "evidence": [ { "database": "UniProtKB", "id": "A5PF62", "url": "https://www.uniprot.org/uniprotkb/A5PF62" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5PF62", "url": "https://www.uniprot.org/uniprotkb/A5PF62" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5PF62", "url": "https://www.uniprot.org/uniprotkb/A5PF62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PLC8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PLC8", "url": "https://www.uniprot.org/uniprotkb/A5PLC8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 106, "chemical_mass": 11781.0, "gene_names": "ptmab;fa94b10;ptmab;wu:fa94b10;zgc:165530", "protein_name": "Prothymosin alpha-B", "disease": [ { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5PLC8", "url": "https://www.uniprot.org/uniprotkb/A5PLC8" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A5PLC8", "url": "https://www.uniprot.org/uniprotkb/A5PLC8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A5PLC8", "url": "https://www.uniprot.org/uniprotkb/A5PLC8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A5PLC8", "url": "https://www.uniprot.org/uniprotkb/A5PLC8" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A5PLC8", "url": "https://www.uniprot.org/uniprotkb/A5PLC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5PLC8-1", "start_pos": "10", "end_pos": "10", "site_lbl": "Thr10", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A5PLC8", "url": "https://www.uniprot.org/uniprotkb/A5PLC8" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A5PLC8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A5PLC8" } ] } ] }, { "uniprot_canonical_ac": "A5PLC8-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Ser8", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A5PLC8", "url": "https://www.uniprot.org/uniprotkb/A5PLC8" }, { "database": "PubMed", "id": "18307296", "url": "https://glygen.org/publication/PubMed/18307296" }, { "database": "iPTMnet", "id": "A5PLC8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A5PLC8" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PLK2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PLK2", "url": "https://www.uniprot.org/uniprotkb/A5PLK2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 270, "chemical_mass": 29625.0, "gene_names": "lhpp;lhpp;zgc:165670", "protein_name": "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5PLK2", "url": "https://www.uniprot.org/uniprotkb/A5PLK2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5PLK2", "url": "https://www.uniprot.org/uniprotkb/A5PLK2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A5PLK2", "url": "https://www.uniprot.org/uniprotkb/A5PLK2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A5PLK2", "url": "https://www.uniprot.org/uniprotkb/A5PLK2" } ], "pmid": "" }, { "name": "inorganic diphosphate phosphatase activity", "id": "GO:0004427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004427", "evidence": [ { "database": "UniProtKB", "id": "A5PLK2", "url": "https://www.uniprot.org/uniprotkb/A5PLK2" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A5PLK2", "url": "https://www.uniprot.org/uniprotkb/A5PLK2" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphate-containing compound metabolic process", "id": "GO:0006796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006796", "evidence": [ { "database": "UniProtKB", "id": "A5PLK2", "url": "https://www.uniprot.org/uniprotkb/A5PLK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PM92-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PM92", "url": "https://www.uniprot.org/uniprotkb/A5PM92" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 454, "chemical_mass": 52882.0, "gene_names": "ppil4;ppil4;wu:fi40d03;zgc:63746", "protein_name": "Peptidyl-prolyl cis-trans isomerase", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A5PM92", "url": "https://www.uniprot.org/uniprotkb/A5PM92" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A5PM92", "url": "https://www.uniprot.org/uniprotkb/A5PM92" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5PM92", "url": "https://www.uniprot.org/uniprotkb/A5PM92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMF6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMF6", "url": "https://www.uniprot.org/uniprotkb/A5PMF6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 604, "chemical_mass": 70832.0, "gene_names": "colgalt1;colgalt1b;colgalt1;glt25d1;si:ch211-114l13.7;zgc:110667", "protein_name": "Procollagen galactosyltransferase 1", "disease": [ { "disease_id": "DOID:0112315", "name": "brain small vessel disease 3", "description": "A brain small vessel disease characterized by impaired basement membrane morphology resulting in increased fragility of cerebral blood vessels and an increased risk of intracranial bleeds of variable severity that has_material_basis_in homozygous or compound heterozygous mutation in the COLGALT1 gene on chromosome 19p13.11.", "url": "https://disease-ontology.org/term/DOID:0112315", "evidence": [ { "id": "0112315", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112315" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A5PMF6", "url": "https://www.uniprot.org/uniprotkb/A5PMF6" } ], "pmid": "" } ], "molecular_function": [ { "name": "procollagen galactosyltransferase activity", "id": "GO:0050211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050211", "evidence": [ { "database": "UniProtKB", "id": "A5PMF6", "url": "https://www.uniprot.org/uniprotkb/A5PMF6" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of collagen fibril organization", "id": "GO:1904028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904028", "evidence": [ { "database": "UniProtKB", "id": "A5PMF6", "url": "https://www.uniprot.org/uniprotkb/A5PMF6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5PMF6-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Asn166", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 166, "start_aa": "Asn", "end_pos": 166, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn166", "evidence": [ { "id": "A5PMF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMF6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5PMF6-1", "start_pos": "363", "end_pos": "363", "site_lbl": "Asn363", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 363, "start_aa": "Asn", "end_pos": 363, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn363", "evidence": [ { "id": "A5PMF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMF6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5PMF6-1", "start_pos": "561", "end_pos": "561", "site_lbl": "Asn561", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 561, "start_aa": "Asn", "end_pos": 561, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn561", "evidence": [ { "id": "A5PMF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMF6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5PMF6-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Asn78", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 78, "start_aa": "Asn", "end_pos": 78, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn78", "evidence": [ { "id": "A5PMF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMF6#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMG8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 828, "chemical_mass": 91527.0, "gene_names": "sort1b;sort1b;sort1l;sort1;wu:fj17g07;wu:fj22b04", "protein_name": "Sortilin", "disease": [ { "disease_id": "DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta.", "url": "https://disease-ontology.org/term/DOID:7693", "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" } ], "molecular_function": [ { "name": "neurotensin receptor activity, non-G protein-coupled", "id": "GO:0030379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030379", "evidence": [ { "database": "UniProtKB", "id": "A5PMG8", "url": "https://www.uniprot.org/uniprotkb/A5PMG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMI4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMI4", "url": "https://www.uniprot.org/uniprotkb/A5PMI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 265, "chemical_mass": 30395.0, "gene_names": "srd5a1;srd5a1;zgc:153768", "protein_name": "3-oxo-5-alpha-steroid 4-dehydrogenase", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:11132", "name": "prostatic hypertrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:11132", "evidence": [ { "id": "11132", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11132" } ], "weight": 0.0 }, { "disease_id": "DOID:12700", "name": "hyperprolactinemia", "description": "An acquired metabolic disease that has_material_basis_in the presence of abnormally-high levels of prolactin in the blood.", "url": "https://disease-ontology.org/term/DOID:12700", "evidence": [ { "id": "12700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12700" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A5PMI4", "url": "https://www.uniprot.org/uniprotkb/A5PMI4" } ], "pmid": "" }, { "name": "male gonad development", "id": "GO:0008584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008584", "evidence": [ { "database": "UniProtKB", "id": "A5PMI4", "url": "https://www.uniprot.org/uniprotkb/A5PMI4" } ], "pmid": "" }, { "name": "androgen biosynthetic process", "id": "GO:0006702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006702", "evidence": [ { "database": "UniProtKB", "id": "A5PMI4", "url": "https://www.uniprot.org/uniprotkb/A5PMI4" } ], "pmid": "" } ], "cellular_component": [ { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A5PMI4", "url": "https://www.uniprot.org/uniprotkb/A5PMI4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A5PMI4", "url": "https://www.uniprot.org/uniprotkb/A5PMI4" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-oxo-5-alpha-steroid 4-dehydrogenase activity", "id": "GO:0003865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003865", "evidence": [ { "database": "UniProtKB", "id": "A5PMI4", "url": "https://www.uniprot.org/uniprotkb/A5PMI4" } ], "pmid": "" }, { "name": "3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity", "id": "GO:0047751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047751", "evidence": [ { "database": "UniProtKB", "id": "A5PMI4", "url": "https://www.uniprot.org/uniprotkb/A5PMI4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMM5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 567, "chemical_mass": 64247.0, "gene_names": "snx18a;si:dkey-193c22.4;snx18a", "protein_name": "Sorting nexin", "disease": [ { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" }, { "name": "cleavage furrow formation", "id": "GO:0036089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036089", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" }, { "name": "plasma membrane tubulation", "id": "GO:0097320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097320", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A5PMM5", "url": "https://www.uniprot.org/uniprotkb/A5PMM5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5PMM5-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 87, "start_aa": "Thr", "end_pos": 87, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr87", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMP7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 194, "chemical_mass": 22603.0, "gene_names": "pdgfaa;pdgfa-2;pdgfaa;pdgfa;zgc:100777", "protein_name": "Platelet-derived growth factor subunit A", "disease": [ { "disease_id": "DOID:12215", "name": "oligohydramnios", "description": "A placenta disease that is characterized by a deficiency of amniotic fluid sometimes resulting in an embryonic defect through adherence between embryo and amnion.", "url": "https://disease-ontology.org/term/DOID:12215", "evidence": [ { "id": "12215", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12215" } ], "weight": 0.0 }, { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2526", "name": "prostate adenocarcinoma", "description": "A prostate carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2526", "evidence": [ { "id": "2526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2526" } ], "weight": 0.0 }, { "disease_id": "DOID:2696", "name": "Leydig cell tumor", "description": "A sex cord-gonadal stromal tumor that secretes testosterone characterized by excessive proliferation of Leydig cells located_in ovary or testicle.", "url": "https://disease-ontology.org/term/DOID:2696", "evidence": [ { "id": "2696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2696" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:4989", "name": "pancreatitis", "description": "A pancreas disease that is characterized by inflammation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:4989", "evidence": [ { "id": "4989", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4989" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:8549", "name": "chronic ulcer of skin", "description": "", "url": "https://disease-ontology.org/term/DOID:8549", "evidence": [ { "id": "8549", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8549" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "platelet-derived growth factor receptor binding", "id": "GO:0005161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005161", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" } ], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "positive regulation of cell division", "id": "GO:0051781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051781", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "platelet-derived growth factor receptor signaling pathway", "id": "GO:0048008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048008", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "cardiac muscle progenitor cell migration to the midline involved in heart field formation", "id": "GO:0003261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003261", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5PMP7", "url": "https://www.uniprot.org/uniprotkb/A5PMP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5PMW0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMW0", "url": "https://www.uniprot.org/uniprotkb/A5PMW0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 702, "chemical_mass": 79471.0, "gene_names": "slc44a5a;ctl5a;si:dkey-189n19.2;slc44a5", "protein_name": "Choline transporter-like protein 5-A", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A5PMW0", "url": "https://www.uniprot.org/uniprotkb/A5PMW0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5PMW0", "url": "https://www.uniprot.org/uniprotkb/A5PMW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A5PMW0", "url": "https://www.uniprot.org/uniprotkb/A5PMW0" } ], "pmid": "" }, { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A5PMW0", "url": "https://www.uniprot.org/uniprotkb/A5PMW0" } ], "pmid": "" }, { "name": "choline transmembrane transporter activity", "id": "GO:0015220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015220", "evidence": [ { "database": "UniProtKB", "id": "A5PMW0", "url": "https://www.uniprot.org/uniprotkb/A5PMW0" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A5PMW0", "url": "https://www.uniprot.org/uniprotkb/A5PMW0" } ], "pmid": "" }, { "name": "choline transport", "id": "GO:0015871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015871", "evidence": [ { "database": "UniProtKB", "id": "A5PMW0", "url": "https://www.uniprot.org/uniprotkb/A5PMW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5PMW0-1", "start_pos": "120", "end_pos": "120", "site_lbl": "Asn120", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 120, "start_aa": "Asn", "end_pos": 120, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn120", "evidence": [ { "id": "A5PMW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMW0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5PMW0-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Asn173", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 173, "start_aa": "Asn", "end_pos": 173, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn173", "evidence": [ { "id": "A5PMW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMW0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5PMW0-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Asn180", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 180, "start_aa": "Asn", "end_pos": 180, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn180", "evidence": [ { "id": "A5PMW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMW0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A5PMW0-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WUE8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 363, "chemical_mass": 40023.0, "gene_names": "e2f5;E2F4;cb735;e2f5;zgc:111879", "protein_name": "", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10286", "name": "prostate carcinoma", "description": "A prostate cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:10286", "evidence": [ { "id": "10286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10286" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 } ], "biological_process": [ { "name": "multi-ciliated epithelial cell differentiation", "id": "GO:1903251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903251", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" }, { "name": "female somatic sex determination", "id": "GO:0019101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019101", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A5WUE8", "url": "https://www.uniprot.org/uniprotkb/A5WUE8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5WUE8-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Thr223", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 223, "start_aa": "Thr", "end_pos": 223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr223", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A5WUE8-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Thr227", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 227, "start_aa": "Thr", "end_pos": 227, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr227", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WUL3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUL3", "url": "https://www.uniprot.org/uniprotkb/A5WUL3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 198, "chemical_mass": 22681.0, "gene_names": "med22;med22;si:ch73-278c20.1;si:dkey-226m8.2;surf5;wu:fj45h07;zgc:86721", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A5WUL3", "url": "https://www.uniprot.org/uniprotkb/A5WUL3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A5WUL3", "url": "https://www.uniprot.org/uniprotkb/A5WUL3" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A5WUL3", "url": "https://www.uniprot.org/uniprotkb/A5WUL3" } ], "pmid": "" } ], "cellular_component": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A5WUL3", "url": "https://www.uniprot.org/uniprotkb/A5WUL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WUT7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 512, "chemical_mass": 58709.0, "gene_names": "riok2;riok2;wu:fe48f07;zgc:55376;zgc:77493", "protein_name": "Serine/threonine-protein kinase RIO2", "disease": [], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "pmid": "" } ], "biological_process": [ { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "A5WUT7", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WUT8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUT8", "url": "https://www.uniprot.org/uniprotkb/A5WUT8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 2532, "chemical_mass": 286825.0, "gene_names": "epg5;si:dkey-165i4.3", "protein_name": "Ectopic P granules protein 5 homolog", "disease": [ { "disease_id": "DOID:0060356", "name": "Vici syndrome", "description": "A syndrome characterized by callosal agenesis, cataracts, cardiomyopathy, combined immunodeficiency and hypopigmentation. It has_material_basis_in mutation in the EPG5 gene on chromosome 18q12.3.", "url": "https://disease-ontology.org/term/DOID:0060356", "evidence": [ { "id": "0060356", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060356" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A5WUT8", "url": "https://www.uniprot.org/uniprotkb/A5WUT8" } ], "pmid": "" }, { "name": "intestinal epithelial cell development", "id": "GO:0060576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060576", "evidence": [ { "database": "UniProtKB", "id": "A5WUT8", "url": "https://www.uniprot.org/uniprotkb/A5WUT8" } ], "pmid": "" }, { "name": "intestinal stem cell homeostasis", "id": "GO:0036335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036335", "evidence": [ { "database": "UniProtKB", "id": "A5WUT8", "url": "https://www.uniprot.org/uniprotkb/A5WUT8" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "A5WUT8", "url": "https://www.uniprot.org/uniprotkb/A5WUT8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5WUT8", "url": "https://www.uniprot.org/uniprotkb/A5WUT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5WUT8-1", "start_pos": "1177", "end_pos": "1177", "site_lbl": "Thr1177", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1177, "start_aa": "Thr", "end_pos": 1177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1177", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WUX7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUX7", "url": "https://www.uniprot.org/uniprotkb/A5WUX7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 156, "chemical_mass": 18184.0, "gene_names": "mtrfr;C5H12orf65;gb:ct586343;si:ch211-275j6.5", "protein_name": "Mitochondrial translation release factor in rescue", "disease": [ { "disease_id": "DOID:0110807", "name": "hereditary spastic paraplegia 55", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the C12ORF65 gene on chromosome 12q24.", "url": "https://disease-ontology.org/term/DOID:0110807", "evidence": [ { "id": "0110807", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110807" } ], "weight": 0.0 }, { "disease_id": "DOID:0111487", "name": "combined oxidative phosphorylation deficiency 7", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in C12orf65 on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0111487", "evidence": [ { "id": "0111487", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111487" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A5WUX7", "url": "https://www.uniprot.org/uniprotkb/A5WUX7" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A5WUX7", "url": "https://www.uniprot.org/uniprotkb/A5WUX7" } ], "pmid": "" }, { "name": "translation release factor activity", "id": "GO:0003747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003747", "evidence": [ { "database": "UniProtKB", "id": "A5WUX7", "url": "https://www.uniprot.org/uniprotkb/A5WUX7" } ], "pmid": "" }, { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "A5WUX7", "url": "https://www.uniprot.org/uniprotkb/A5WUX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WUY4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1036, "chemical_mass": 120954.0, "gene_names": "smarca1;si:dkey-148b12.1;smarca1", "protein_name": "", "disease": [], "biological_process": [ { "name": "primitive erythrocyte differentiation", "id": "GO:0060319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060319", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "primitive hemopoiesis", "id": "GO:0060215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060215", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "neural plate anterior/posterior regionalization", "id": "GO:0021999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021999", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "nucleosome array spacer activity", "id": "GO:0140750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140750", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" }, { "name": "ISWI-type complex", "id": "GO:0031010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031010", "evidence": [ { "database": "UniProtKB", "id": "A5WUY4", "url": "https://www.uniprot.org/uniprotkb/A5WUY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WVY2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WVY2", "url": "https://www.uniprot.org/uniprotkb/A5WVY2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 180, "chemical_mass": 20438.0, "gene_names": "akirin2;C6orf166;akirin2;wu:fb16h11;wu:fi04e05;zgc:114001;zgc:55291;zgc:77169", "protein_name": "Akirin-2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5WVY2", "url": "https://www.uniprot.org/uniprotkb/A5WVY2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A5WVY2", "url": "https://www.uniprot.org/uniprotkb/A5WVY2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A5WVY2", "url": "https://www.uniprot.org/uniprotkb/A5WVY2" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A5WVY2", "url": "https://www.uniprot.org/uniprotkb/A5WVY2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A5WVY2", "url": "https://www.uniprot.org/uniprotkb/A5WVY2" } ], "pmid": "" }, { "name": "positive regulation of innate immune response", "id": "GO:0045089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045089", "evidence": [ { "database": "UniProtKB", "id": "A5WVY2", "url": "https://www.uniprot.org/uniprotkb/A5WVY2" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A5WVY2", "url": "https://www.uniprot.org/uniprotkb/A5WVY2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WW21-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 663, "chemical_mass": 75858.0, "gene_names": "rasef;rasef2;rasef;si:ch211-39k3.1;zgc:162879", "protein_name": "Ras and EF-hand domain-containing protein", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "endolysosome", "id": "GO:0036019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036019", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" }, { "name": "zymogen granule exocytosis", "id": "GO:0070625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070625", "evidence": [ { "database": "UniProtKB", "id": "A5WW21", "url": "https://www.uniprot.org/uniprotkb/A5WW21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WW24-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WW24", "url": "https://www.uniprot.org/uniprotkb/A5WW24" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1024, "chemical_mass": 118053.0, "gene_names": "ipo8;Imp8;si:ch211-116i17.1", "protein_name": "Importin-8", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A5WW24", "url": "https://www.uniprot.org/uniprotkb/A5WW24" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A5WW24", "url": "https://www.uniprot.org/uniprotkb/A5WW24" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A5WW24", "url": "https://www.uniprot.org/uniprotkb/A5WW24" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "A5WW24", "url": "https://www.uniprot.org/uniprotkb/A5WW24" } ], "pmid": "" } ], "biological_process": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A5WW24", "url": "https://www.uniprot.org/uniprotkb/A5WW24" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WWB0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 370, "chemical_mass": 42905.0, "gene_names": "usp46;ch73-16a12.1;si:ch73-16a12.1;usp46", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 46", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, GABAergic", "id": "GO:0032228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032228", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A5WWB0", "url": "https://www.uniprot.org/uniprotkb/A5WWB0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WWD5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WWD5", "url": "https://www.uniprot.org/uniprotkb/A5WWD5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 632, "chemical_mass": 71922.0, "gene_names": "man1b1b;man1b1b;man1b1;si:dkey-61l1.3", "protein_name": "alpha-1,2-Mannosidase", "disease": [ { "disease_id": "DOID:0081097", "name": "Rafiq syndrome", "description": "An autosomal recessive intellectual developmental disorder that is characterized by variably impaired intellectual and motor development, a characteristic facial dysmorphism, truncal obesity, and hypotonia and that has_material_basis_in homozygous mutation in the MAN1B1 gene on chromosome 9q34.", "url": "https://disease-ontology.org/term/DOID:0081097", "evidence": [ { "id": "0081097", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081097" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A5WWD5", "url": "https://www.uniprot.org/uniprotkb/A5WWD5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5WWD5", "url": "https://www.uniprot.org/uniprotkb/A5WWD5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A5WWD5", "url": "https://www.uniprot.org/uniprotkb/A5WWD5" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A5WWD5", "url": "https://www.uniprot.org/uniprotkb/A5WWD5" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A5WWD5", "url": "https://www.uniprot.org/uniprotkb/A5WWD5" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A5WWD5", "url": "https://www.uniprot.org/uniprotkb/A5WWD5" } ], "pmid": "" }, { "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "id": "GO:0004571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004571", "evidence": [ { "database": "UniProtKB", "id": "A5WWD5", "url": "https://www.uniprot.org/uniprotkb/A5WWD5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A5WWD5-1", "start_pos": "301", "end_pos": "301", "site_lbl": "Thr301", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 301, "start_aa": "Thr", "end_pos": 301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr301", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A5WWE3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WWE3", "url": "https://www.uniprot.org/uniprotkb/A5WWE3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 296, "chemical_mass": 33174.0, "gene_names": "gtf2h3;fc26a07;gtf2h3-2;gtf2h3;wu:fc26a07;zgc:92759", "protein_name": "General transcription factor IIH subunit 3", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A5WWE3", "url": "https://www.uniprot.org/uniprotkb/A5WWE3" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "A5WWE3", "url": "https://www.uniprot.org/uniprotkb/A5WWE3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A5WWE3", "url": "https://www.uniprot.org/uniprotkb/A5WWE3" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "A5WWE3", "url": "https://www.uniprot.org/uniprotkb/A5WWE3" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "A5WWE3", "url": "https://www.uniprot.org/uniprotkb/A5WWE3" } ], "pmid": "" } ], "cellular_component": [ { "name": "transcription factor TFIIH holo complex", "id": "GO:0005675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005675", "evidence": [ { "database": "UniProtKB", "id": "A5WWE3", "url": "https://www.uniprot.org/uniprotkb/A5WWE3" } ], "pmid": "" }, { "name": "transcription factor TFIIH core complex", "id": "GO:0000439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000439", "evidence": [ { "database": "UniProtKB", "id": "A5WWE3", "url": "https://www.uniprot.org/uniprotkb/A5WWE3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A7MBU6-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A7MBU6", "url": "https://www.uniprot.org/uniprotkb/A7MBU6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 406, "chemical_mass": 48045.0, "gene_names": "tdo2a;fb62b10;tdo2a;tdo2;wu:fb62b10;zgc:103693", "protein_name": "Tryptophan 2,3-dioxygenase A", "disease": [ { "disease_id": "DOID:0111703", "name": "familial hypertryptophanemia", "description": "An amino acid metabolic disorder characterized by elevated urine and plasma tryptophan levels that has_material_basis_in homozygous or compound heterozygous mutation in the TDO2 gene on chromosome 4q32.1.", "url": "https://disease-ontology.org/term/DOID:0111703", "evidence": [ { "id": "0111703", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111703" } ], "weight": 0.0 }, { "disease_id": "DOID:11119", "name": "Gilles de la Tourette syndrome", "description": "A tic disorder that is characterized by multiple physical (motor) tics and at least one vocal (phonic) tic present for more than a year.", "url": "https://disease-ontology.org/term/DOID:11119", "evidence": [ { "id": "11119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11119" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 } ], "biological_process": [ { "name": "L-tryptophan catabolic process to kynurenine", "id": "GO:0019441", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019441", "evidence": [ { "database": "UniProtKB", "id": "A7MBU6", "url": "https://www.uniprot.org/uniprotkb/A7MBU6" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "A7MBU6", "url": "https://www.uniprot.org/uniprotkb/A7MBU6" } ], "pmid": "" }, { "name": "L-tryptophan catabolic process to acetyl-CoA", "id": "GO:0019442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019442", "evidence": [ { "database": "UniProtKB", "id": "A7MBU6", "url": "https://www.uniprot.org/uniprotkb/A7MBU6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A7MBU6", "url": "https://www.uniprot.org/uniprotkb/A7MBU6" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A7MBU6", "url": "https://www.uniprot.org/uniprotkb/A7MBU6" } ], "pmid": "" }, { "name": "L-tryptophan 2,3-dioxygenase activity", "id": "GO:0004833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004833", "evidence": [ { "database": "UniProtKB", "id": "A7MBU6", "url": "https://www.uniprot.org/uniprotkb/A7MBU6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A7MD70-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 590, "chemical_mass": 68964.0, "gene_names": "spdl1;CCDC99;SPDL1;ccdc99;id:ibd2849;spdl1;zgc:171223", "protein_name": "Protein Spindly", "disease": [], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" }, { "name": "protein localization to kinetochore", "id": "GO:0034501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" } ], "molecular_function": [ { "name": "kinetochore binding", "id": "GO:0043515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043515", "evidence": [ { "database": "UniProtKB", "id": "A7MD70", "url": "https://www.uniprot.org/uniprotkb/A7MD70" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A7Y7X5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 761, "chemical_mass": 86356.0, "gene_names": "znf711;ZNF6;sb:eu767;si:dkey-152p16.4;zvep", "protein_name": "Zinc finger protein 711", "disease": [ { "disease_id": "DOID:0112046", "name": "non-syndromic X-linked intellectual disability 97", "description": "A non-syndromic X-linked intellectual disability characterized by mild to moderate intellectual disability with speech delay that has_material_basis_in mutation in the ZNF711 gene on chromosome Xq21.1.", "url": "https://disease-ontology.org/term/DOID:0112046", "evidence": [ { "id": "0112046", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112046" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "vitelline envelope", "id": "GO:0060388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060388", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A7Y7X5", "url": "https://www.uniprot.org/uniprotkb/A7Y7X5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A7YT82-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A7YT82", "url": "https://www.uniprot.org/uniprotkb/A7YT82" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 492, "chemical_mass": 56347.0, "gene_names": "nmt2;NMT 2;fb40e03;nmt2;wu:fb40e03", "protein_name": "Glycylpeptide N-tetradecanoyltransferase 2", "disease": [ { "disease_id": "DOID:0080000", "name": "muscular disease", "description": "A musculoskeletal system disease that affects the muscles.", "url": "https://disease-ontology.org/term/DOID:0080000", "evidence": [ { "id": "0080000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080000" } ], "weight": 0.0 } ], "biological_process": [ { "name": "N-terminal peptidyl-glycine N-myristoylation", "id": "GO:0018008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018008", "evidence": [ { "database": "UniProtKB", "id": "A7YT82", "url": "https://www.uniprot.org/uniprotkb/A7YT82" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A7YT82", "url": "https://www.uniprot.org/uniprotkb/A7YT82" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A7YT82", "url": "https://www.uniprot.org/uniprotkb/A7YT82" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A7YT82", "url": "https://www.uniprot.org/uniprotkb/A7YT82" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycylpeptide N-tetradecanoyltransferase activity", "id": "GO:0004379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004379", "evidence": [ { "database": "UniProtKB", "id": "A7YT82", "url": "https://www.uniprot.org/uniprotkb/A7YT82" } ], "pmid": "" }, { "name": "peptidyl-lysine N6-myristoyltransferase activity", "id": "GO:0018030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018030", "evidence": [ { "database": "UniProtKB", "id": "A7YT82", "url": "https://www.uniprot.org/uniprotkb/A7YT82" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A7YY07-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 327, "chemical_mass": 37546.0, "gene_names": "shfl;shfl;zgc:171711", "protein_name": "Shiftless antiviral inhibitor of ribosomal frameshifting protein homolog", "disease": [], "molecular_function": [ { "name": "sequence-specific mRNA binding", "id": "GO:1990825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990825", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translational termination", "id": "GO:0006449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006449", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" }, { "name": "response to interferon-beta", "id": "GO:0035456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035456", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" }, { "name": "viral translational frameshifting", "id": "GO:0075523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0075523", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" }, { "name": "negative regulation of translational frameshifting", "id": "GO:2001125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001125", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A7YY07", "url": "https://www.uniprot.org/uniprotkb/A7YY07" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8DZ86-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 688, "chemical_mass": 75311.0, "gene_names": "vasna;id:ibd2098;si:ch211-14g12.2;slitl2;vasna;vasn;zgc:110624", "protein_name": "Vasorin", "disease": [], "biological_process": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "pmid": "" }, { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "pmid": "" } ], "molecular_function": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "pmid": "" }, { "name": "Roundabout binding", "id": "GO:0048495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048495", "evidence": [ { "database": "UniProtKB", "id": "A8DZ86", "url": "https://www.uniprot.org/uniprotkb/A8DZ86" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8E7D2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7D2", "url": "https://www.uniprot.org/uniprotkb/A8E7D2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 254, "chemical_mass": 28819.0, "gene_names": "bcdin3d;si:dkey-222f2.2", "protein_name": "Pre-miRNA 5'-monophosphate methyltransferase", "disease": [], "molecular_function": [ { "name": "small RNA 2'-O-methyltransferase activity", "id": "GO:0090486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090486", "evidence": [ { "database": "UniProtKB", "id": "A8E7D2", "url": "https://www.uniprot.org/uniprotkb/A8E7D2" } ], "pmid": "" }, { "name": "O-methyltransferase activity", "id": "GO:0008171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008171", "evidence": [ { "database": "UniProtKB", "id": "A8E7D2", "url": "https://www.uniprot.org/uniprotkb/A8E7D2" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A8E7D2", "url": "https://www.uniprot.org/uniprotkb/A8E7D2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8E7D2", "url": "https://www.uniprot.org/uniprotkb/A8E7D2" } ], "pmid": "" } ], "biological_process": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A8E7D2", "url": "https://www.uniprot.org/uniprotkb/A8E7D2" } ], "pmid": "" }, { "name": "negative regulation of pre-miRNA processing", "id": "GO:2000632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000632", "evidence": [ { "database": "UniProtKB", "id": "A8E7D2", "url": "https://www.uniprot.org/uniprotkb/A8E7D2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8E7G4-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7G4", "url": "https://www.uniprot.org/uniprotkb/A8E7G4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 349, "chemical_mass": 39662.0, "gene_names": "dennd10;dennd10;fam45a;fam45;si:ch211-117n7.2;wu:fc44d12;wu:fd19e06", "protein_name": "DENN domain-containing protein 10", "disease": [], "biological_process": [ { "name": "regulation of early endosome to late endosome transport", "id": "GO:2000641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000641", "evidence": [ { "database": "UniProtKB", "id": "A8E7G4", "url": "https://www.uniprot.org/uniprotkb/A8E7G4" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A8E7G4", "url": "https://www.uniprot.org/uniprotkb/A8E7G4" } ], "pmid": "" }, { "name": "endosome transport via multivesicular body sorting pathway", "id": "GO:0032509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032509", "evidence": [ { "database": "UniProtKB", "id": "A8E7G4", "url": "https://www.uniprot.org/uniprotkb/A8E7G4" } ], "pmid": "" } ], "cellular_component": [ { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A8E7G4", "url": "https://www.uniprot.org/uniprotkb/A8E7G4" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A8E7G4", "url": "https://www.uniprot.org/uniprotkb/A8E7G4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A8E7G4", "url": "https://www.uniprot.org/uniprotkb/A8E7G4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8E7G5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 316, "chemical_mass": 34567.0, "gene_names": "sfxn4;im:7151335;sfxn4;si:ch211-117n7.3;zgc:153199", "protein_name": "Sideroflexin-4", "disease": [ { "disease_id": "DOID:0111484", "name": "combined oxidative phosphorylation deficiency 18", "description": "A combined oxidative phosphorylation deficiency characterized by intrauterine growth retardation, hypotonia, visual impairment, speech delay, and lactic acidosis that has_material_basis_in homozygous or compound heterozygous mutation in the SFXN4 gene on chromosome 10q26.11.", "url": "https://disease-ontology.org/term/DOID:0111484", "evidence": [ { "id": "0111484", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111484" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transporter activity", "id": "GO:0015075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015075", "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "pmid": "" } ], "biological_process": [ { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "pmid": "" }, { "name": "cellular respiration", "id": "GO:0045333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045333", "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "pmid": "" }, { "name": "mitochondrial transmembrane transport", "id": "GO:1990542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990542", "evidence": [ { "database": "UniProtKB", "id": "A8E7G5", "url": "https://www.uniprot.org/uniprotkb/A8E7G5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8E7N7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1277, "chemical_mass": 141967.0, "gene_names": "pogza;im:7136628;pogza;si:dkey-200h23.5;wu:fe24e11", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0070067", "name": "White-Sutton syndrome", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the POGZ gene on chromosome 1q21.3.", "url": "https://disease-ontology.org/term/DOID:0070067", "evidence": [ { "id": "0070067", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070067" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "pmid": "" } ], "biological_process": [ { "name": "spinal cord development", "id": "GO:0021510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021510", "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "pmid": "" }, { "name": "otic vesicle development", "id": "GO:0071599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071599", "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "pmid": "" }, { "name": "larval locomotory behavior", "id": "GO:0008345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008345", "evidence": [ { "database": "UniProtKB", "id": "A8E7N7", "url": "https://www.uniprot.org/uniprotkb/A8E7N7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8E7N7-1", "start_pos": "140", "end_pos": "140", "site_lbl": "Thr140", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 140, "start_aa": "Thr", "end_pos": 140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr140", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "A8E7N7-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Thr185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 185, "start_aa": "Thr", "end_pos": 185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr185", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8E7N9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7N9", "url": "https://www.uniprot.org/uniprotkb/A8E7N9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 412, "chemical_mass": 47068.0, "gene_names": "gdf6b;bmp13b;dynamo;gdf6a;gdf6b;si:ch211-244a23.2", "protein_name": "Growth/differentiation factor 6-B", "disease": [ { "disease_id": "DOID:0060836", "name": "isolated microphthalmia 4", "description": "An isolated microphthalmia that has_material_basis_in mutation in the GDF6 gene on chromosome 8q22.", "url": "https://disease-ontology.org/term/DOID:0060836", "evidence": [ { "id": "0060836", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060836" } ], "weight": 0.0 }, { "disease_id": "DOID:0080589", "name": "Klippel-Feil syndrome 1", "description": "A Klippel-Feil syndrome that has_material_basis_in heterozygous mutation in the GDF6 gene on chromosome 8q22.", "url": "https://disease-ontology.org/term/DOID:0080589", "evidence": [ { "id": "0080589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080589" } ], "weight": 0.0 }, { "disease_id": "DOID:0081320", "name": "multiple synostoses syndrome 4", "description": "A multiple synostoses syndrome that is characterized by fusion of carpal and tarsal bones, as well as conductive hearing loss and that has_material_basis_in heterozygous mutation in the GDF6 gene on chromosome 8q22.", "url": "https://disease-ontology.org/term/DOID:0081320", "evidence": [ { "id": "0081320", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081320" } ], "weight": 0.0 }, { "disease_id": "DOID:0110217", "name": "Leber congenital amaurosis 17", "description": "A Leber congenital amaurosis that has_material_basis_in mutation in the GDF6 gene on chromosome 8q22.", "url": "https://disease-ontology.org/term/DOID:0110217", "evidence": [ { "id": "0110217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110217" } ], "weight": 0.0 }, { "disease_id": "DOID:674", "name": "cleft palate", "description": "An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.", "url": "https://disease-ontology.org/term/DOID:674", "evidence": [ { "id": "674", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:674" } ], "weight": 0.0 }, { "disease_id": "DOID:9296", "name": "cleft lip", "description": "An orofacial cleft that is characterized by a congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences.", "url": "https://disease-ontology.org/term/DOID:9296", "evidence": [ { "id": "9296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9296" } ], "weight": 0.0 } ], "biological_process": [ { "name": "circulatory system development", "id": "GO:0072359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072359", "evidence": [ { "database": "UniProtKB", "id": "A8E7N9", "url": "https://www.uniprot.org/uniprotkb/A8E7N9" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "A8E7N9", "url": "https://www.uniprot.org/uniprotkb/A8E7N9" } ], "pmid": "" }, { "name": "tube morphogenesis", "id": "GO:0035239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035239", "evidence": [ { "database": "UniProtKB", "id": "A8E7N9", "url": "https://www.uniprot.org/uniprotkb/A8E7N9" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A8E7N9", "url": "https://www.uniprot.org/uniprotkb/A8E7N9" } ], "pmid": "" } ], "molecular_function": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A8E7N9", "url": "https://www.uniprot.org/uniprotkb/A8E7N9" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A8E7N9", "url": "https://www.uniprot.org/uniprotkb/A8E7N9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8E7N9-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Asn95", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 95, "start_aa": "Asn", "end_pos": 95, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn95", "evidence": [ { "id": "A8E7N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7N9#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8HAJ8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8HAJ8", "url": "https://www.uniprot.org/uniprotkb/A8HAJ8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 562, "chemical_mass": 62828.0, "gene_names": "c8b;c8b;si:ch211-188c16.3;wu:fi18d09", "protein_name": "Complement component C8 beta chain", "disease": [ { "disease_id": "DOID:0060302", "name": "type II complement component 8 deficiency", "description": "A complement deficiency that is characterized by deficiency of the beta subunit of complement protein 8, which causes increased susceptibility to recurrent bacterial infections, especially to Neisseria meningitidis, and has_material_basis_in autosomal recessive inheritance of mutation in the C8B gene, which produces the beta subunit of complement component 8 important in forming membrane attack complexes.", "url": "https://disease-ontology.org/term/DOID:0060302", "evidence": [ { "id": "0060302", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060302" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A8HAJ8", "url": "https://www.uniprot.org/uniprotkb/A8HAJ8" } ], "pmid": "" }, { "name": "membrane attack complex", "id": "GO:0005579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005579", "evidence": [ { "database": "UniProtKB", "id": "A8HAJ8", "url": "https://www.uniprot.org/uniprotkb/A8HAJ8" } ], "pmid": "" }, { "name": "other organism cell membrane", "id": "GO:0044218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044218", "evidence": [ { "database": "UniProtKB", "id": "A8HAJ8", "url": "https://www.uniprot.org/uniprotkb/A8HAJ8" } ], "pmid": "" } ], "biological_process": [ { "name": "killing of cells of another organism", "id": "GO:0031640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031640", "evidence": [ { "database": "UniProtKB", "id": "A8HAJ8", "url": "https://www.uniprot.org/uniprotkb/A8HAJ8" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "A8HAJ8", "url": "https://www.uniprot.org/uniprotkb/A8HAJ8" } ], "pmid": "" }, { "name": "complement activation", "id": "GO:0006956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006956", "evidence": [ { "database": "UniProtKB", "id": "A8HAJ8", "url": "https://www.uniprot.org/uniprotkb/A8HAJ8" } ], "pmid": "" }, { "name": "complement activation, alternative pathway", "id": "GO:0006957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006957", "evidence": [ { "database": "UniProtKB", "id": "A8HAJ8", "url": "https://www.uniprot.org/uniprotkb/A8HAJ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8KB34-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8KB34", "url": "https://www.uniprot.org/uniprotkb/A8KB34" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 315, "chemical_mass": 35535.0, "gene_names": "aspa;ACY-2;aspa;zgc:171507", "protein_name": "Aspartoacylase", "disease": [ { "disease_id": "DOID:3613", "name": "Canavan disease", "description": "A leukodystrophy characterized by onset in early infancy, atonia of neck muscles, hypotonia, hyperextension of legs and flexion of arms, blindness, severe mental defect, megalocephaly, and death by 18 months on the average that has_material_basis_in homozygous or compound heterozygous mutation in ASPA gene encoding aspartoacylase on chromosome 17p13.", "url": "https://disease-ontology.org/term/DOID:3613", "evidence": [ { "id": "3613", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3613" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8KB34", "url": "https://www.uniprot.org/uniprotkb/A8KB34" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A8KB34", "url": "https://www.uniprot.org/uniprotkb/A8KB34" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "A8KB34", "url": "https://www.uniprot.org/uniprotkb/A8KB34" } ], "pmid": "" }, { "name": "aspartoacylase activity", "id": "GO:0019807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019807", "evidence": [ { "database": "UniProtKB", "id": "A8KB34", "url": "https://www.uniprot.org/uniprotkb/A8KB34" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A8KB34", "url": "https://www.uniprot.org/uniprotkb/A8KB34" } ], "pmid": "" }, { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides", "id": "GO:0016811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016811", "evidence": [ { "database": "UniProtKB", "id": "A8KB34", "url": "https://www.uniprot.org/uniprotkb/A8KB34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8KBL7-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8KBL7", "url": "https://www.uniprot.org/uniprotkb/A8KBL7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 353, "chemical_mass": 40488.0, "gene_names": "mettl2a;mettl2a;mettl2;zgc:110598", "protein_name": "tRNA N(3)-cytidine methyltransferase METTL2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8KBL7", "url": "https://www.uniprot.org/uniprotkb/A8KBL7" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A8KBL7", "url": "https://www.uniprot.org/uniprotkb/A8KBL7" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA (cytidine) methyltransferase activity", "id": "GO:0016427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016427", "evidence": [ { "database": "UniProtKB", "id": "A8KBL7", "url": "https://www.uniprot.org/uniprotkb/A8KBL7" } ], "pmid": "" }, { "name": "tRNA (cytidine-3-)-methyltransferase activity", "id": "GO:0052735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052735", "evidence": [ { "database": "UniProtKB", "id": "A8KBL7", "url": "https://www.uniprot.org/uniprotkb/A8KBL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WFS8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WFS8", "url": "https://www.uniprot.org/uniprotkb/A8WFS8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 316, "chemical_mass": 36062.0, "gene_names": "pgap3;perld1;pgap3;zgc:171485", "protein_name": "GPI-specific phospholipase A2-like PGAP3", "disease": [ { "disease_id": "DOID:0070431", "name": "hyperphosphatasia with impaired intellectual development syndrome", "description": "An autosomal recessive intellectual developmental disorder characterized by hyperphosphatasia and intellectual disability. Distinctive facial features including hypertelorism, long palpebral fissures, a nose with a broad bridge and a rounded tip, downturned corners of the mouth, and a thin upper lip are also often observed.", "url": "https://disease-ontology.org/term/DOID:0070431", "evidence": [ { "id": "0070431", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070431" } ], "weight": 0.0 }, { "disease_id": "DOID:0070436", "name": "hyperphosphatasia with impaired intellectual development syndrome 4", "description": "A hyperphosphatasia with impaired intellectual development syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the PGAP3 gene on chromosome 17q12.", "url": "https://disease-ontology.org/term/DOID:0070436", "evidence": [ { "id": "0070436", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070436" } ], "weight": 0.0 }, { "disease_id": "DOID:0080809", "name": "chronic asthma", "description": "An asthma that is characterized by the development of persistent airway inflammation and recurrent attacks of breathlessness and wheezing, which vary in severity and frequency.", "url": "https://disease-ontology.org/term/DOID:0080809", "evidence": [ { "id": "0080809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080809" } ], "weight": 0.0 }, { "disease_id": "DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness.", "url": "https://disease-ontology.org/term/DOID:9415", "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A8WFS8", "url": "https://www.uniprot.org/uniprotkb/A8WFS8" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A8WFS8", "url": "https://www.uniprot.org/uniprotkb/A8WFS8" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "A8WFS8", "url": "https://www.uniprot.org/uniprotkb/A8WFS8" } ], "pmid": "" } ], "biological_process": [ { "name": "brain morphogenesis", "id": "GO:0048854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048854", "evidence": [ { "database": "UniProtKB", "id": "A8WFS8", "url": "https://www.uniprot.org/uniprotkb/A8WFS8" } ], "pmid": "" }, { "name": "GPI anchor metabolic process", "id": "GO:0006505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006505", "evidence": [ { "database": "UniProtKB", "id": "A8WFS8", "url": "https://www.uniprot.org/uniprotkb/A8WFS8" } ], "pmid": "" }, { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A8WFS8", "url": "https://www.uniprot.org/uniprotkb/A8WFS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8WFS8-1", "start_pos": "36", "end_pos": "36", "site_lbl": "Asn36", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 36, "start_aa": "Asn", "end_pos": 36, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn36", "evidence": [ { "id": "A8WFS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WFS8#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WG88-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WG88", "url": "https://www.uniprot.org/uniprotkb/A8WG88" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 301, "chemical_mass": 35172.0, "gene_names": "tmx2a;im:7138651;tmx2a;zgc:172264", "protein_name": "Thioredoxin-related transmembrane protein 2-A", "disease": [], "molecular_function": [ { "name": "disulfide oxidoreductase activity", "id": "GO:0015036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015036", "evidence": [ { "database": "UniProtKB", "id": "A8WG88", "url": "https://www.uniprot.org/uniprotkb/A8WG88" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A8WG88", "url": "https://www.uniprot.org/uniprotkb/A8WG88" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A8WG88", "url": "https://www.uniprot.org/uniprotkb/A8WG88" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A8WG88", "url": "https://www.uniprot.org/uniprotkb/A8WG88" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "A8WG88", "url": "https://www.uniprot.org/uniprotkb/A8WG88" } ], "pmid": "" } ], "biological_process": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A8WG88", "url": "https://www.uniprot.org/uniprotkb/A8WG88" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WGA3-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WGA3", "url": "https://www.uniprot.org/uniprotkb/A8WGA3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 687, "chemical_mass": 75776.0, "gene_names": "lrfn1l;lrfn1l;zgc:172282", "protein_name": "Leucine-rich repeat and fibronectin type III domain-containing protein 1-like protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8WGA3", "url": "https://www.uniprot.org/uniprotkb/A8WGA3" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A8WGA3", "url": "https://www.uniprot.org/uniprotkb/A8WGA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8WGA3-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Asn331", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 331, "start_aa": "Asn", "end_pos": 331, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn331", "evidence": [ { "id": "A8WGA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGA3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A8WGA3-1", "start_pos": "340", "end_pos": "340", "site_lbl": "Asn340", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 340, "start_aa": "Asn", "end_pos": 340, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn340", "evidence": [ { "id": "A8WGA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGA3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A8WGA3-1", "start_pos": "346", "end_pos": "346", "site_lbl": "Asn346", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 346, "start_aa": "Asn", "end_pos": 346, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn346", "evidence": [ { "id": "A8WGA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGA3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A8WGA3-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Asn383", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 383, "start_aa": "Asn", "end_pos": 383, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn383", "evidence": [ { "id": "A8WGA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGA3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A8WGA3-1", "start_pos": "410", "end_pos": "410", "site_lbl": "Asn410", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 410, "start_aa": "Asn", "end_pos": 410, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn410", "evidence": [ { "id": "A8WGA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGA3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A8WGA3-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Asn450", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 450, "start_aa": "Asn", "end_pos": 450, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn450", "evidence": [ { "id": "A8WGA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGA3#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A8WGA3-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Asn73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 73, "start_aa": "Asn", "end_pos": 73, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn73", "evidence": [ { "id": "A8WGA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGA3#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WGT1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WGT1", "url": "https://www.uniprot.org/uniprotkb/A8WGT1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 279, "chemical_mass": 32605.0, "gene_names": "ch25hl2;zgc:175201", "protein_name": "Cholesterol 25-hydroxylase-like protein 2", "disease": [], "molecular_function": [ { "name": "C-4 methylsterol oxidase activity", "id": "GO:0000254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000254", "evidence": [ { "database": "UniProtKB", "id": "A8WGT1", "url": "https://www.uniprot.org/uniprotkb/A8WGT1" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A8WGT1", "url": "https://www.uniprot.org/uniprotkb/A8WGT1" } ], "pmid": "" }, { "name": "steroid hydroxylase activity", "id": "GO:0008395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008395", "evidence": [ { "database": "UniProtKB", "id": "A8WGT1", "url": "https://www.uniprot.org/uniprotkb/A8WGT1" } ], "pmid": "" } ], "biological_process": [ { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A8WGT1", "url": "https://www.uniprot.org/uniprotkb/A8WGT1" } ], "pmid": "" }, { "name": "sterol biosynthetic process", "id": "GO:0016126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016126", "evidence": [ { "database": "UniProtKB", "id": "A8WGT1", "url": "https://www.uniprot.org/uniprotkb/A8WGT1" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A8WGT1", "url": "https://www.uniprot.org/uniprotkb/A8WGT1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8WGT1-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Asn13", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 13, "start_aa": "Asn", "end_pos": 13, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn13", "evidence": [ { "id": "A8WGT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGT1#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "A8WGT1-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Asn6", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 6, "start_aa": "Asn", "end_pos": 6, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn6", "evidence": [ { "id": "A8WGT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WGT1#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A8WHZ0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 379, "chemical_mass": 44015.0, "gene_names": "b4galt2;b4galt2;si:ch211-261p7.4", "protein_name": "Beta-1,4-galactosyltransferase", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "galactosyltransferase activity", "id": "GO:0008378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008378", "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "pmid": "" }, { "name": "N-acetyllactosamine synthase activity", "id": "GO:0003945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003945", "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A8WHZ0", "url": "https://www.uniprot.org/uniprotkb/A8WHZ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9C3P0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9C3P0", "url": "https://www.uniprot.org/uniprotkb/A9C3P0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 285, "chemical_mass": 31986.0, "gene_names": "mlec;mlec;si:dkey-117k10.5", "protein_name": "Malectin", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A9C3P0", "url": "https://www.uniprot.org/uniprotkb/A9C3P0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A9C3P0", "url": "https://www.uniprot.org/uniprotkb/A9C3P0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A9C3P0", "url": "https://www.uniprot.org/uniprotkb/A9C3P0" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A9C3P0", "url": "https://www.uniprot.org/uniprotkb/A9C3P0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A9C3P0-1", "start_pos": "261", "end_pos": "261", "site_lbl": "Asn261", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 261, "start_aa": "Asn", "end_pos": 261, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn261", "evidence": [ { "id": "A9C3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C3P0#ptm_processing" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9C3T0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9C3T0", "url": "https://www.uniprot.org/uniprotkb/A9C3T0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 397, "chemical_mass": 44691.0, "gene_names": "prkar2aa;prkar2aa;wu:fb55f12;wu:fj29e12;wu:fj33e06;zgc:153742", "protein_name": "cAMP-dependent protein kinase type II-alpha regulatory subunit", "disease": [ { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase A catalytic subunit binding", "id": "GO:0034236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034236", "evidence": [ { "database": "UniProtKB", "id": "A9C3T0", "url": "https://www.uniprot.org/uniprotkb/A9C3T0" } ], "pmid": "" }, { "name": "cAMP-dependent protein kinase inhibitor activity", "id": "GO:0004862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004862", "evidence": [ { "database": "UniProtKB", "id": "A9C3T0", "url": "https://www.uniprot.org/uniprotkb/A9C3T0" } ], "pmid": "" }, { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "A9C3T0", "url": "https://www.uniprot.org/uniprotkb/A9C3T0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A9C3T0", "url": "https://www.uniprot.org/uniprotkb/A9C3T0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A9C3T0", "url": "https://www.uniprot.org/uniprotkb/A9C3T0" } ], "pmid": "" }, { "name": "cAMP-dependent protein kinase complex", "id": "GO:0005952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005952", "evidence": [ { "database": "UniProtKB", "id": "A9C3T0", "url": "https://www.uniprot.org/uniprotkb/A9C3T0" } ], "pmid": "" } ], "biological_process": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A9C3T0", "url": "https://www.uniprot.org/uniprotkb/A9C3T0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9C458-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 151, "chemical_mass": 17140.0, "gene_names": "pla2g1b;pla2g1b", "protein_name": "Phospholipase A2", "disease": [], "molecular_function": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" }, { "name": "arachidonate secretion", "id": "GO:0050482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050482", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" }, { "name": "phosphatidylcholine metabolic process", "id": "GO:0046470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046470", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" }, { "name": "phosphatidylglycerol metabolic process", "id": "GO:0046471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046471", "evidence": [ { "database": "UniProtKB", "id": "A9C458", "url": "https://www.uniprot.org/uniprotkb/A9C458" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9JRE2-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JRE2", "url": "https://www.uniprot.org/uniprotkb/A9JRE2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 353, "chemical_mass": 37980.0, "gene_names": "mri1;CH73-131E21.1;M1Pi;mri1;zgc:172216", "protein_name": "Methylthioribose-1-phosphate isomerase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A9JRE2", "url": "https://www.uniprot.org/uniprotkb/A9JRE2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A9JRE2", "url": "https://www.uniprot.org/uniprotkb/A9JRE2" } ], "pmid": "" } ], "biological_process": [ { "name": "L-methionine salvage from methylthioadenosine", "id": "GO:0019509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019509", "evidence": [ { "database": "UniProtKB", "id": "A9JRE2", "url": "https://www.uniprot.org/uniprotkb/A9JRE2" } ], "pmid": "" } ], "molecular_function": [ { "name": "S-methyl-5-thioribose-1-phosphate isomerase activity", "id": "GO:0046523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046523", "evidence": [ { "database": "UniProtKB", "id": "A9JRE2", "url": "https://www.uniprot.org/uniprotkb/A9JRE2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "A9JRX0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JRX0", "url": "https://www.uniprot.org/uniprotkb/A9JRX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 489, "chemical_mass": 55880.0, "gene_names": "msl1l1;MSL-1;fj57g05;msl1a;msl1l1;wu:fj57g05;zgc:175094", "protein_name": "Male-specific lethal 1-like 1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A9JRX0", "url": "https://www.uniprot.org/uniprotkb/A9JRX0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A9JRX0", "url": "https://www.uniprot.org/uniprotkb/A9JRX0" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A9JRX0", "url": "https://www.uniprot.org/uniprotkb/A9JRX0" } ], "pmid": "" }, { "name": "MSL complex", "id": "GO:0072487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072487", "evidence": [ { "database": "UniProtKB", "id": "A9JRX0", "url": "https://www.uniprot.org/uniprotkb/A9JRX0" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A9JRX0", "url": "https://www.uniprot.org/uniprotkb/A9JRX0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A9JRX0", "url": "https://www.uniprot.org/uniprotkb/A9JRX0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A9JRX0", "url": "https://www.uniprot.org/uniprotkb/A9JRX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R024-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R024", "url": "https://www.uniprot.org/uniprotkb/B0R024" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 794, "chemical_mass": 87317.0, "gene_names": "ap1g2;ap1g2;fc07e03;si:zc14a17.4;wu:fc07e03;zgc:153847", "protein_name": "AP-1 complex subunit gamma", "disease": [], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "B0R024", "url": "https://www.uniprot.org/uniprotkb/B0R024" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "B0R024", "url": "https://www.uniprot.org/uniprotkb/B0R024" } ], "pmid": "" }, { "name": "vasculature development", "id": "GO:0001944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001944", "evidence": [ { "database": "UniProtKB", "id": "B0R024", "url": "https://www.uniprot.org/uniprotkb/B0R024" } ], "pmid": "" }, { "name": "axis elongation", "id": "GO:0003401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003401", "evidence": [ { "database": "UniProtKB", "id": "B0R024", "url": "https://www.uniprot.org/uniprotkb/B0R024" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "B0R024", "url": "https://www.uniprot.org/uniprotkb/B0R024" } ], "pmid": "" } ], "cellular_component": [ { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "B0R024", "url": "https://www.uniprot.org/uniprotkb/B0R024" } ], "pmid": "" } ], "molecular_function": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "B0R024", "url": "https://www.uniprot.org/uniprotkb/B0R024" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R0J5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R0J5", "url": "https://www.uniprot.org/uniprotkb/B0R0J5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 549, "chemical_mass": 60348.0, "gene_names": "mgrn1b;mgrn1b", "protein_name": "E3 ubiquitin-protein ligase", "disease": [], "cellular_component": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "B0R0J5", "url": "https://www.uniprot.org/uniprotkb/B0R0J5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0R0J5", "url": "https://www.uniprot.org/uniprotkb/B0R0J5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B0R0J5", "url": "https://www.uniprot.org/uniprotkb/B0R0J5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "B0R0J5", "url": "https://www.uniprot.org/uniprotkb/B0R0J5" } ], "pmid": "" } ], "biological_process": [ { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "B0R0J5", "url": "https://www.uniprot.org/uniprotkb/B0R0J5" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "B0R0J5", "url": "https://www.uniprot.org/uniprotkb/B0R0J5" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "B0R0J5", "url": "https://www.uniprot.org/uniprotkb/B0R0J5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B0R0J5-1", "start_pos": "461", "end_pos": "461", "site_lbl": "Thr461", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 461, "start_aa": "Thr", "end_pos": 461, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr461", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] }, { "uniprot_canonical_ac": "B0R0J5-1", "start_pos": "74", "end_pos": "74", "site_lbl": "Thr74", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 74, "start_aa": "Thr", "end_pos": 74, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr74", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ] } ], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R0T1-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R0T1", "url": "https://www.uniprot.org/uniprotkb/B0R0T1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 1896, "chemical_mass": 211974.0, "gene_names": "vwa8;si:dkey-18l1.1", "protein_name": "von Willebrand factor A domain-containing protein 8", "disease": [ { "disease_id": "DOID:0061110", "name": "retinitis pigmentosa 97", "description": "A retinitis pigmentosa characterized by onset of night blindness and visual field defects in the first decade of life, with later onset of reduced visual acuity that has_material_basis_in heterozygous mutation in the VWA8 gene on chromosome 13q14.", "url": "https://disease-ontology.org/term/DOID:0061110", "evidence": [ { "id": "0061110", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061110" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B0R0T1", "url": "https://www.uniprot.org/uniprotkb/B0R0T1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "B0R0T1", "url": "https://www.uniprot.org/uniprotkb/B0R0T1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0R0T1", "url": "https://www.uniprot.org/uniprotkb/B0R0T1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B0R0T1", "url": "https://www.uniprot.org/uniprotkb/B0R0T1" } ], "pmid": "" } ], "biological_process": [ { "name": "notochord development", "id": "GO:0030903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030903", "evidence": [ { "database": "UniProtKB", "id": "B0R0T1", "url": "https://www.uniprot.org/uniprotkb/B0R0T1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R0V8-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 481, "chemical_mass": 55147.0, "gene_names": "atp6v1h;atp6v1h;chunp6890", "protein_name": "V-type proton ATPase subunit H", "disease": [ { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V1 domain", "id": "GO:0000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000221", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" } ], "biological_process": [ { "name": "retina development in camera-type eye", "id": "GO:0060041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060041", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" }, { "name": "bone development", "id": "GO:0060348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060348", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" }, { "name": "pigmentation", "id": "GO:0043473", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043473", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" }, { "name": "eye pigmentation", "id": "GO:0048069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048069", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" }, { "name": "positive regulation of neural retina development", "id": "GO:0061075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061075", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" } ], "molecular_function": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "B0R0V8", "url": "https://www.uniprot.org/uniprotkb/B0R0V8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R191-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R191", "url": "https://www.uniprot.org/uniprotkb/B0R191" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 121, "chemical_mass": 13014.0, "gene_names": "cxcl11.6;cxcl11.6;cxcl11af;si:ch211-202a12.8", "protein_name": "C-X-C motif chemokine 11-6", "disease": [ { "disease_id": "DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction.", "url": "https://disease-ontology.org/term/DOID:13406", "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ], "weight": 0.0 }, { "disease_id": "DOID:13949", "name": "interstitial cystitis", "description": "", "url": "https://disease-ontology.org/term/DOID:13949", "evidence": [ { "id": "13949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13949" } ], "weight": 0.0 }, { "disease_id": "DOID:2799", "name": "bronchiolitis obliterans", "description": "A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults.", "url": "https://disease-ontology.org/term/DOID:2799", "evidence": [ { "id": "2799", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2799" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B0R191", "url": "https://www.uniprot.org/uniprotkb/B0R191" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response", "id": "GO:0006952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006952", "evidence": [ { "database": "UniProtKB", "id": "B0R191", "url": "https://www.uniprot.org/uniprotkb/B0R191" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "B0R191", "url": "https://www.uniprot.org/uniprotkb/B0R191" } ], "pmid": "" } ], "molecular_function": [ { "name": "chemoattractant activity", "id": "GO:0042056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042056", "evidence": [ { "database": "UniProtKB", "id": "B0R191", "url": "https://www.uniprot.org/uniprotkb/B0R191" } ], "pmid": "" }, { "name": "chemokine activity", "id": "GO:0008009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008009", "evidence": [ { "database": "UniProtKB", "id": "B0R191", "url": "https://www.uniprot.org/uniprotkb/B0R191" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R1D0-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 418, "chemical_mass": 47260.0, "gene_names": "psmc4;psmc4;wu:fe38b10;zgc:63709", "protein_name": "26S proteasome regulatory subunit 6B", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "pmid": "" }, { "name": "proteasome-activating activity", "id": "GO:0036402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036402", "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "B0R1D0", "url": "https://www.uniprot.org/uniprotkb/B0R1D0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R1D5-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R1D5", "url": "https://www.uniprot.org/uniprotkb/B0R1D5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 682, "chemical_mass": 77678.0, "gene_names": "suz12b;fc31h10;im:7153578;si:dkey-10p5.2;suz12b;suz12;wu:fc31h10", "protein_name": "Polycomb protein suz12-B", "disease": [ { "disease_id": "DOID:0080016", "name": "spina bifida", "description": "A neural tube defect that is characterized by incomplete closing of the spine and membranes around the spinal cord during early development.", "url": "https://disease-ontology.org/term/DOID:0080016", "evidence": [ { "id": "0080016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080016" } ], "weight": 0.0 }, { "disease_id": "DOID:5176", "name": "renal Wilms' tumor", "description": "", "url": "https://disease-ontology.org/term/DOID:5176", "evidence": [ { "id": "5176", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5176" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0R1D5", "url": "https://www.uniprot.org/uniprotkb/B0R1D5" } ], "pmid": "" }, { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "B0R1D5", "url": "https://www.uniprot.org/uniprotkb/B0R1D5" } ], "pmid": "" }, { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "B0R1D5", "url": "https://www.uniprot.org/uniprotkb/B0R1D5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "B0R1D5", "url": "https://www.uniprot.org/uniprotkb/B0R1D5" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "B0R1D5", "url": "https://www.uniprot.org/uniprotkb/B0R1D5" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B0R1D5", "url": "https://www.uniprot.org/uniprotkb/B0R1D5" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "B0R1D5", "url": "https://www.uniprot.org/uniprotkb/B0R1D5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" }, { "uniprot_canonical_ac": "B0R1E9-1", "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R1E9", "url": "https://www.uniprot.org/uniprotkb/B0R1E9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "length": 152, "chemical_mass": 17313.0, "gene_names": "mgst1.2;mgst1.2;si:dkey-8m7.1;zgc:92357", "protein_name": "Microsomal glutathione S-transferase 1", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "B0R1E9", "url": "https://www.uniprot.org/uniprotkb/B0R1E9" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B0R1E9", "url": "https://www.uniprot.org/uniprotkb/B0R1E9" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "B0R1E9", "url": "https://www.uniprot.org/uniprotkb/B0R1E9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "B0R1E9", "url": "https://www.uniprot.org/uniprotkb/B0R1E9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.zebrafish.10" } ]