[ { "uniprot_canonical_ac": "Q9VBL6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBL6", "url": "https://www.uniprot.org/uniprotkb/Q9VBL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 75, "chemical_mass": 7106.0, "gene_names": "Mst57Da;BcDNA:GH19893;CG9074;Dmel\\CG9074;Mst57Da;Mst57D;bs30d07.y1;mst(2)ag-1;mst-1;mst57D", "protein_name": "Accessory gland-specific peptide 57Da", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VBL6", "url": "https://www.uniprot.org/uniprotkb/Q9VBL6" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q9VBL6", "url": "https://www.uniprot.org/uniprotkb/Q9VBL6" } ], "pmid": "" }, { "name": "regulation of female receptivity", "id": "GO:0045924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045924", "evidence": [ { "database": "UniProtKB", "id": "Q9VBL6", "url": "https://www.uniprot.org/uniprotkb/Q9VBL6" } ], "pmid": "" }, { "name": "egg-laying behavior", "id": "GO:0018991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018991", "evidence": [ { "database": "UniProtKB", "id": "Q9VBL6", "url": "https://www.uniprot.org/uniprotkb/Q9VBL6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VBL6", "url": "https://www.uniprot.org/uniprotkb/Q9VBL6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VBL6", "url": "https://www.uniprot.org/uniprotkb/Q9VBL6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VBW9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 419, "chemical_mass": 45273.0, "gene_names": "danr;CG13651;Danr;Dmel\\CG13651;danr;hern", "protein_name": "Protein distal antenna-related", "disease": [], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" }, { "name": "segment specification", "id": "GO:0007379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007379", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" }, { "name": "antennal development", "id": "GO:0007469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007469", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" }, { "name": "central nervous system formation", "id": "GO:0021556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021556", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VBW9", "url": "https://www.uniprot.org/uniprotkb/Q9VBW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VBW9-1", "start_pos": "293", "end_pos": "293", "site_lbl": "Thr293", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 293, "start_aa": "Thr", "end_pos": 293, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr293", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VBX2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 367, "chemical_mass": 41891.0, "gene_names": "Mocs2B;CG10238;Dmel\\CG10238;Dromel_CG10238_FBtr0084782_mocs_mORF;MBIP/dMoaE;MOCS2;Mbip;Mocs2B;Mocs2b;Mocs2;dMbip;dMoaE", "protein_name": "Molybdopterin synthase catalytic subunit", "disease": [ { "disease_id": "DOID:0111163", "name": "molybdenum cofactor deficiency type B", "description": "A molybdenum cofactor deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the MOCS2 gene on chromosome 5q11.", "url": "https://disease-ontology.org/term/DOID:0111163", "evidence": [ { "id": "0111163", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111163" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" }, { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" }, { "name": "molybdopterin synthase complex", "id": "GO:1990140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990140", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" }, { "name": "Mo-molybdopterin cofactor biosynthetic process", "id": "GO:0006777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006777", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" } ], "molecular_function": [ { "name": "molybdopterin synthase activity", "id": "GO:0030366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030366", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX2", "url": "https://www.uniprot.org/uniprotkb/Q9VBX2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VC45-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1954, "chemical_mass": 230180.0, "gene_names": "asp;ASP;Asp;CG6875;Dm Asp;Dmel\\CG6875;anon-96Aa;anon-WO0118547.279;asp", "protein_name": "Protein abnormal spindle", "disease": [ { "disease_id": "DOID:0070280", "name": "primary autosomal recessive microcephaly 5", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the ASPM gene on chromosome 1q31.", "url": "https://disease-ontology.org/term/DOID:0070280", "evidence": [ { "id": "0070280", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070280" } ], "weight": 0.0 }, { "disease_id": "DOID:0070296", "name": "autosomal recessive primary microcephaly", "description": "A primary microcephaly characterized by microcephaly present at birth, where the brain is small but has normal architecture, and nonprogressive mental retardation that has_material_basis_in an autosomal recessive mutation.", "url": "https://disease-ontology.org/term/DOID:0070296", "evidence": [ { "id": "0070296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070296" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "kinetochore organization", "id": "GO:0051383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051383", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "brain morphogenesis", "id": "GO:0048854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048854", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "centrosome duplication", "id": "GO:0051298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051298", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "spindle organization", "id": "GO:0007051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007051", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "establishment of meiotic spindle localization", "id": "GO:0051295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051295", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "astral microtubule nucleation", "id": "GO:0030954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030954", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "female germ-line stem cell asymmetric division", "id": "GO:0048132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048132", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "cystoblast division", "id": "GO:0007282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007282", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "ovarian fusome organization", "id": "GO:0030723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030723", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "germarium-derived oocyte differentiation", "id": "GO:0030706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030706", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "microtubule associated complex", "id": "GO:0005875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005875", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" }, { "name": "myosin light chain binding", "id": "GO:0032027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032027", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Thr273", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 273, "start_aa": "Thr", "end_pos": 273, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr273", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Ser151", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "360", "end_pos": "360", "site_lbl": "Ser360", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "364", "end_pos": "364", "site_lbl": "Thr364", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Ser388", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Ser390", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Ser395", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "398", "end_pos": "398", "site_lbl": "Ser398", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Ser491", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "495", "end_pos": "495", "site_lbl": "Ser495", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "497", "end_pos": "497", "site_lbl": "Ser497", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "501", "end_pos": "501", "site_lbl": "Ser501", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "504", "end_pos": "504", "site_lbl": "Ser504", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] }, { "uniprot_canonical_ac": "Q9VC45-1", "start_pos": "514", "end_pos": "514", "site_lbl": "Ser514", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VC45", "url": "https://www.uniprot.org/uniprotkb/Q9VC45" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VC45", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VC45" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VC70-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC70", "url": "https://www.uniprot.org/uniprotkb/Q9VC70" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 737, "chemical_mass": 83822.0, "gene_names": "DZIP1;CG13617;DZIP1;Dmel\\CG13617;Dzip1;dzip1", "protein_name": "Cilium assembly protein DZIP1L", "disease": [ { "disease_id": "DOID:0080273", "name": "polycystic kidney disease 5", "description": "A autosomal recessive polycystic kidney disease that has_material_basis_in autosomal dominant inheritance of homozygous mutation in the DZIP1L gene on chromosome 3q22.", "url": "https://disease-ontology.org/term/DOID:0080273", "evidence": [ { "id": "0080273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080273" } ], "weight": 0.0 }, { "disease_id": "DOID:0110861", "name": "autosomal recessive polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion.", "url": "https://disease-ontology.org/term/DOID:0110861", "evidence": [ { "id": "0110861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110861" } ], "weight": 0.0 }, { "disease_id": "DOID:0112175", "name": "spermatogenic failure 47", "description": "A spermatogenic failure characterized by asthenoteratospermia,reduced sperm concentrations, and immotile spermatozoa with short or absent flagella as well as centriolar abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the DZIP1 gene on chromosome 13q32.1.", "url": "https://disease-ontology.org/term/DOID:0112175", "evidence": [ { "id": "0112175", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112175" } ], "weight": 0.0 }, { "disease_id": "DOID:12270", "name": "coloboma", "description": "An eye disease characterized by missing pieces of tissue in structures that form the eye, such as the iris, retina, choroid or optic disc.", "url": "https://disease-ontology.org/term/DOID:12270", "evidence": [ { "id": "12270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12270" } ], "weight": 0.0 }, { "disease_id": "DOID:988", "name": "mitral valve prolapse", "description": "A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.", "url": "https://disease-ontology.org/term/DOID:988", "evidence": [ { "id": "988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:988" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VC70", "url": "https://www.uniprot.org/uniprotkb/Q9VC70" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VC70", "url": "https://www.uniprot.org/uniprotkb/Q9VC70" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q9VC70", "url": "https://www.uniprot.org/uniprotkb/Q9VC70" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VC70", "url": "https://www.uniprot.org/uniprotkb/Q9VC70" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "Q9VC70", "url": "https://www.uniprot.org/uniprotkb/Q9VC70" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VC70", "url": "https://www.uniprot.org/uniprotkb/Q9VC70" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VC70", "url": "https://www.uniprot.org/uniprotkb/Q9VC70" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VCD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCD0", "url": "https://www.uniprot.org/uniprotkb/Q9VCD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 516, "chemical_mass": 57376.0, "gene_names": "GatB;CG5463;Dmel\\CG5463;GatB", "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD0", "url": "https://www.uniprot.org/uniprotkb/Q9VCD0" } ], "pmid": "" }, { "name": "glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "id": "GO:0050567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050567", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD0", "url": "https://www.uniprot.org/uniprotkb/Q9VCD0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD0", "url": "https://www.uniprot.org/uniprotkb/Q9VCD0" } ], "pmid": "" }, { "name": "glutamyl-tRNA(Gln) amidotransferase complex", "id": "GO:0030956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030956", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD0", "url": "https://www.uniprot.org/uniprotkb/Q9VCD0" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD0", "url": "https://www.uniprot.org/uniprotkb/Q9VCD0" } ], "pmid": "" }, { "name": "glutaminyl-tRNAGln biosynthesis via transamidation", "id": "GO:0070681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070681", "evidence": [ { "database": "UniProtKB", "id": "Q9VCD0", "url": "https://www.uniprot.org/uniprotkb/Q9VCD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VCU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2249, "chemical_mass": 255330.0, "gene_names": "Dcr-1;CG4792;DCR-1;DCR1;DICER-1;DICER;Dcr-1;Dcr1;Dcr;Dicer1;Dicer;Dmel\\CG4792;cg4792;dcr 1;dcr-1;dcr1;dicer-1;dicer1;dicer;dmDcr1", "protein_name": "Endoribonuclease Dcr-1", "disease": [ { "disease_id": "DOID:0050489", "name": "multinodular goiter", "description": "A goiter characterized by a multinodular enlargement of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:0050489", "evidence": [ { "id": "0050489", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050489" } ], "weight": 0.0 }, { "disease_id": "DOID:0050745", "name": "diffuse large B-cell lymphoma", "description": "A large B-cell lymphoma that is consisting of medium-sized to large B cells with a diffuse growth pattern.", "url": "https://disease-ontology.org/term/DOID:0050745", "evidence": [ { "id": "0050745", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050745" } ], "weight": 0.0 }, { "disease_id": "DOID:0080615", "name": "nephroma", "description": "A kidney benign neoplasm that is located_in the kidney cortex.", "url": "https://disease-ontology.org/term/DOID:0080615", "evidence": [ { "id": "0080615", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080615" } ], "weight": 0.0 }, { "disease_id": "DOID:0081063", "name": "DICER1 syndrome", "description": "A syndrome that is characterized by an increased risk of developing pleuropulmonary blastoma, multinodular goiter, ovarian Sertoli-Leydig cell tumors, and/or other types of tumors, and that has_material_basis_in heterozygous mutation in the DICER1 gene on chromosome 14q32. Mutations of the gene encoding the endoribonuclease, Dicer, disrupts the biogenesis and processing of miRNAs with subsequent disruption in control of gene expression.", "url": "https://disease-ontology.org/term/DOID:0081063", "evidence": [ { "id": "0081063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081063" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:11198", "name": "DiGeorge syndrome", "description": "A syndrome that has_material_basis_in a large deletion of the chromosome 22q11.2 region which includes the DGS gene needed for development of the thymus and related glands with subsequent lack of T-cell production.", "url": "https://disease-ontology.org/term/DOID:11198", "evidence": [ { "id": "11198", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11198" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:4769", "name": "pleuropulmonary blastoma", "description": "A pulmonary blastoma that derives_from the lung or pleural cavity.", "url": "https://disease-ontology.org/term/DOID:4769", "evidence": [ { "id": "4769", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4769" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "RISC complex assembly", "id": "GO:0070922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070922", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031054", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated post-transcriptional gene silencing", "id": "GO:0035194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035194", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "miRNA processing", "id": "GO:0035196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035196", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "siRNA processing", "id": "GO:0030422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030422", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "germarium-derived female germ-line cyst formation", "id": "GO:0030727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030727", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "mitotic cell cycle, embryonic", "id": "GO:0045448", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045448", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "pole cell formation", "id": "GO:0007279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007279", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "germarium-derived oocyte fate determination", "id": "GO:0007294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007294", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "segment polarity determination", "id": "GO:0007367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007367", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "germ-line stem cell division", "id": "GO:0042078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042078", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "ribonuclease III activity", "id": "GO:0004525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004525", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "deoxyribonuclease I activity", "id": "GO:0004530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004530", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "pre-miRNA binding", "id": "GO:0070883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070883", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" }, { "name": "RISC-loading complex", "id": "GO:0070578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070578", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "1312", "end_pos": "1312", "site_lbl": "Ser1312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1312, "start_aa": "Ser", "end_pos": 1312, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1312", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VCU9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VCU9" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "1970", "end_pos": "1970", "site_lbl": "Thr1970", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1970, "start_aa": "Thr", "end_pos": 1970, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1970", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "450", "end_pos": "450", "site_lbl": "Thr450", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 450, "start_aa": "Thr", "end_pos": 450, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr450", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Thr452", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 452, "start_aa": "Thr", "end_pos": 452, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr452", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Thr454", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 454, "start_aa": "Thr", "end_pos": 454, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr454", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "1423", "end_pos": "1423", "site_lbl": "Ser1423", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VCU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VCU9" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "1877", "end_pos": "1877", "site_lbl": "Ser1877", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VCU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VCU9" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "1880", "end_pos": "1880", "site_lbl": "Ser1880", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VCU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VCU9" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "1749", "end_pos": "1749", "site_lbl": "Asp1749", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Cleaves the 5' (top) strand but not the 3' (bottom) strand of pre-miRNA.", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" }, { "database": "PubMed", "id": "17666393", "url": "https://glygen.org/publication/PubMed/17666393" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "1908", "end_pos": "1908", "site_lbl": "Glu1908", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Cleaves the 5' (top) strand but not the 3' (bottom) strand of pre-miRNA. Abolishes cleavage of pre-miRNA; when associated with A-2139.", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" }, { "database": "PubMed", "id": "21926993", "url": "https://glygen.org/publication/PubMed/21926993" }, { "database": "PubMed", "id": "17666393", "url": "https://glygen.org/publication/PubMed/17666393" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "2036", "end_pos": "2036", "site_lbl": "Asp2036", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Cleaves the 3' (bottom) strand but not the 5' (top) strand of pre-miRNA.", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" }, { "database": "PubMed", "id": "17666393", "url": "https://glygen.org/publication/PubMed/17666393" } ] } ] }, { "uniprot_canonical_ac": "Q9VCU9-1", "start_pos": "2139", "end_pos": "2139", "site_lbl": "Glu2139", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Cleaves the 3' (bottom) strand but not the 5' (top) strand of pre-miRNA. Abolishes cleavage of pre-miRNA; when associated with A-1908.", "evidence": [ { "database": "UniProtKB", "id": "Q9VCU9", "url": "https://www.uniprot.org/uniprotkb/Q9VCU9" }, { "database": "PubMed", "id": "17666393", "url": "https://glygen.org/publication/PubMed/17666393" }, { "database": "PubMed", "id": "21926993", "url": "https://glygen.org/publication/PubMed/21926993" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VD74-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 397, "chemical_mass": 46253.0, "gene_names": "Gr93c;93F.3;CG13411;CG31173;Dmel\\CG31173;GR93F.3;GR93c;Gr93F3;Gr93c", "protein_name": "Putative gustatory receptor 93c", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9VD74", "url": "https://www.uniprot.org/uniprotkb/Q9VD74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VD76-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 419, "chemical_mass": 48834.0, "gene_names": "Gr93a;93F.1;CG13417;Dmel\\CG13417;GR93F.1;GR93a;GR93;Gr93F1;Gr93a", "protein_name": "Gustatory receptor for bitter taste 93a", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "response to caffeine", "id": "GO:0031000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031000", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9VD76", "url": "https://www.uniprot.org/uniprotkb/Q9VD76" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VDE6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 766, "chemical_mass": 88726.0, "gene_names": "Sec15;3R41;CG7034;Dmel\\CG7034;Sec15p;Sec15;dsec15;sec15", "protein_name": "Exocyst complex component 6", "disease": [ { "disease_id": "DOID:0112200", "name": "spondyloepimetaphyseal dysplasia with joint laxity type 3", "description": "A spondyloepimetaphyseal dysplasia with joint laxity characterized by multiple joint dislocations at birth, severe joint laxity, scoliosis, gracile metacarpals and metatarsals, delayed bone age, and poorly ossified carpal and tarsal bones that has_material_basis_in homozygous or compound heterozygous mutation in the EXOC6B gene on chromosome 2p13.2.", "url": "https://disease-ontology.org/term/DOID:0112200", "evidence": [ { "id": "0112200", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112200" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "rhabdomere", "id": "GO:0016028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016028", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "phototaxis", "id": "GO:0042331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042331", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDE6-1", "start_pos": "659", "end_pos": "659", "site_lbl": "Asn659", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Disrupts interaction with RAB11.", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" }, { "database": "PubMed", "id": "16155582", "url": "https://glygen.org/publication/PubMed/16155582" } ] } ] }, { "uniprot_canonical_ac": "Q9VDE6-1", "start_pos": "663", "end_pos": "663", "site_lbl": "Met663", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "A", "comment": "Disrupts interaction with RAB11.", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" }, { "database": "PubMed", "id": "16155582", "url": "https://glygen.org/publication/PubMed/16155582" } ] } ] }, { "uniprot_canonical_ac": "Q9VDE6-1", "start_pos": "667", "end_pos": "667", "site_lbl": "Phe667", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Disrupts interaction with RAB11.", "evidence": [ { "database": "UniProtKB", "id": "Q9VDE6", "url": "https://www.uniprot.org/uniprotkb/Q9VDE6" }, { "database": "PubMed", "id": "16155582", "url": "https://glygen.org/publication/PubMed/16155582" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VDH6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 868, "chemical_mass": 99639.0, "gene_names": "Ir93a;93a;CG17274;CG17275;CG42315;CT35907;DmelIR93a;Dmel\\CG42315;IR93a;IR93;Ir93a;ir93a", "protein_name": "Ionotropic receptor 93a", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception", "id": "GO:0050907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050907", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" }, { "name": "glutamate receptor activity", "id": "GO:0008066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008066", "evidence": [ { "database": "UniProtKB", "id": "Q9VDH6", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Asn205", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 205, "start_aa": "Asn", "end_pos": 205, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn205", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Asn294", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 294, "start_aa": "Asn", "end_pos": 294, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn294", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "305", "end_pos": "305", "site_lbl": "Asn305", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 305, "start_aa": "Asn", "end_pos": 305, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn305", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Asn38", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 38, "start_aa": "Asn", "end_pos": 38, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn38", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "432", "end_pos": "432", "site_lbl": "Asn432", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 432, "start_aa": "Asn", "end_pos": 432, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn432", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "475", "end_pos": "475", "site_lbl": "Asn475", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 475, "start_aa": "Asn", "end_pos": 475, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn475", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "499", "end_pos": "499", "site_lbl": "Asn499", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 499, "start_aa": "Asn", "end_pos": 499, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn499", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Asn543", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 543, "start_aa": "Asn", "end_pos": 543, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn543", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VDH6-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Asn691", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 691, "start_aa": "Asn", "end_pos": 691, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn691", "evidence": [ { "id": "Q9VDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDH6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VDM6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDM6", "url": "https://www.uniprot.org/uniprotkb/Q9VDM6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 273, "chemical_mass": 30526.0, "gene_names": "eIF3g2;CG10881;Dmel\\CG10881;cg10881;eIF3-S4;eIF3g2;eIF3gb", "protein_name": "Eukaryotic translation initiation factor 3 subunit G-2", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9VDM6", "url": "https://www.uniprot.org/uniprotkb/Q9VDM6" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9VDM6", "url": "https://www.uniprot.org/uniprotkb/Q9VDM6" } ], "pmid": "" } ], "biological_process": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q9VDM6", "url": "https://www.uniprot.org/uniprotkb/Q9VDM6" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q9VDM6", "url": "https://www.uniprot.org/uniprotkb/Q9VDM6" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q9VDM6", "url": "https://www.uniprot.org/uniprotkb/Q9VDM6" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q9VDM6", "url": "https://www.uniprot.org/uniprotkb/Q9VDM6" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q9VDM6", "url": "https://www.uniprot.org/uniprotkb/Q9VDM6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VDW6-5", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3598, "chemical_mass": 410414.0, "gene_names": "Dys;CG17750;CG31175;CG34157;CG7240;CG7243;CG7344;DLP186;DLP1;DLP2;DLP3;DLP;DYS;DmDLP;DmDYS;Dmel\\CG34157;Dp117;Dp186;Dp205;Dys;GI3046716;IDLP;det;dmDLP;dmDp186;dmDys;dys", "protein_name": "Dystrophin, isoforms A/C/F/G/H", "disease": [ { "disease_id": "DOID:0050925", "name": "small intestine carcinoid neuroendocrine tumor", "description": "A neuroendocrine tumor that has_material_basis_in cells of the neuroendocrine system and that is located in the small intestine.", "url": "https://disease-ontology.org/term/DOID:0050925", "evidence": [ { "id": "0050925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050925" } ], "weight": 0.0 }, { "disease_id": "DOID:0110461", "name": "dilated cardiomyopathy 3B", "description": "A dilated cardiomyopathy that has_material_basis_in mutation in the dystrophin (DMD) gene encoding dystrophin on chromosome Xp21.", "url": "https://disease-ontology.org/term/DOID:0110461", "evidence": [ { "id": "0110461", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110461" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:11723", "name": "Duchenne muscular dystrophy", "description": "A muscular dystrophy that has_material_basis_in X-linked mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing muscle weakness and muscle atrophy initially involving the lower extremities and eventually affecting the whole body. It affects males whereas females can be carriers. The symptoms start before the age of six and may appear at infancy.", "url": "https://disease-ontology.org/term/DOID:11723", "evidence": [ { "id": "11723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11723" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1561", "name": "cognitive disorder", "description": "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.", "url": "https://disease-ontology.org/term/DOID:1561", "evidence": [ { "id": "1561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1561" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:4724", "name": "brain edema", "description": "A brain disease that is characterized by excess accumulation of fluid in the intracellular and/or extracellular spaces of the brain, has_symptom nausea, has_symptom vomiting, has_symptom blurred vision, has_symptom seizure, has_symptom coma.", "url": "https://disease-ontology.org/term/DOID:4724", "evidence": [ { "id": "4724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4724" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 }, { "disease_id": "DOID:9883", "name": "Becker muscular dystrophy", "description": "A muscular dystrophy that involves slowly worsening muscle weakness of the legs and pelvis, and has_material_basis_in X-linked recessive inheritance of mutation in the dystrophin gene on chromosome Xp21.", "url": "https://disease-ontology.org/term/DOID:9883", "evidence": [ { "id": "9883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9883" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "dystrophin-associated glycoprotein complex", "id": "GO:0016010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016010", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of short-term neuronal synaptic plasticity", "id": "GO:0048172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048172", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "maintenance of presynaptic active zone structure", "id": "GO:0048790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048790", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "muscle cell cellular homeostasis", "id": "GO:0046716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046716", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "regulation of neurotransmitter secretion", "id": "GO:0046928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046928", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "muscle cell development", "id": "GO:0055001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055001", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "imaginal disc-derived wing vein specification", "id": "GO:0007474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007474", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "imaginal disc-derived wing vein morphogenesis", "id": "GO:0008586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008586", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "WW domain binding", "id": "GO:0050699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050699", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDW6-5", "start_pos": "1832", "end_pos": "1832", "site_lbl": "Ser1832", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VDW6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VDW6" } ] } ] }, { "uniprot_canonical_ac": "Q9VDW6-5", "start_pos": "1838", "end_pos": "1838", "site_lbl": "Ser1838", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VDW6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VDW6" } ] } ] }, { "uniprot_canonical_ac": "Q9VDW6-5", "start_pos": "3207", "end_pos": "3207", "site_lbl": "Ser3207", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VDW6", "url": "https://www.uniprot.org/uniprotkb/Q9VDW6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VDW6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VDW6" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VE00-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VE00", "url": "https://www.uniprot.org/uniprotkb/Q9VE00" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 536, "chemical_mass": 61777.0, "gene_names": "Cyp12a4;12a4;CG6042;CYP12A4;Cyp12A4;Cyp12a4;Dmel\\CG6042;P450;Rst(Luf);cyp12a4", "protein_name": "Probable cytochrome P450 12a4, mitochondrial", "disease": [ { "disease_id": "DOID:0050860", "name": "colorectal adenoma", "description": "An intestinal benign neoplasm that has_material_basis_in epithelial tissue of glandular origin and is located_in colon and located_in rectum.", "url": "https://disease-ontology.org/term/DOID:0050860", "evidence": [ { "id": "0050860", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050860" } ], "weight": 0.0 }, { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0061136", "name": "infantile hypercalcemia 1", "description": "A hypercalcemia that has_material_basis_in homozygous or compound heterozygous mutation in the CYP24A1 gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0061136", "evidence": [ { "id": "0061136", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061136" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 }, { "disease_id": "DOID:0080815", "name": "childhood-onset asthma", "description": "A chronic asthma that is characterized by first presentation in early childhood.", "url": "https://disease-ontology.org/term/DOID:0080815", "evidence": [ { "id": "0080815", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080815" } ], "weight": 0.0 }, { "disease_id": "DOID:0080886", "name": "vitamin D-dependent rickets type 1A", "description": "A vitamin D-dependent rickets that is characterized by abnormally low levels of calcitriol and that has_material_basis_in mutation in the gene encoding 25-hydroxyvitamin D3-1-alpha-hydroxylase (CYP27B1) on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0080886", "evidence": [ { "id": "0080886", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080886" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10609", "name": "rickets", "description": "A bone remodeling disease that has_material_basis_in impaired mineralization or calcification of bones before epiphyseal closure due to deficiency or impaired metabolism of vitamin D, phosphorus or calcium which results_in softening and deformity located_in bone.", "url": "https://disease-ontology.org/term/DOID:10609", "evidence": [ { "id": "10609", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10609" } ], "weight": 0.0 }, { "disease_id": "DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy.", "url": "https://disease-ontology.org/term/DOID:11714", "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1993", "name": "rectum cancer", "description": "A colorectal cancer that is located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:1993", "evidence": [ { "id": "1993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1993" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:2527", "name": "nephrosis", "description": "A proteinuria that is characterized by the leaking of blood protein into the urine, swelling or edema, and degenerative lesions without inflammation.", "url": "https://disease-ontology.org/term/DOID:2527", "evidence": [ { "id": "2527", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2527" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3713", "name": "ovary adenocarcinoma", "description": "An ovarian carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3713", "evidence": [ { "id": "3713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3713" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3905", "name": "lung carcinoma", "description": "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.", "url": "https://disease-ontology.org/term/DOID:3905", "evidence": [ { "id": "3905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3905" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4810", "name": "cerebrotendinous xanthomatosis", "description": "A xanthomatosis that is characterized by a deficiency in the production of the bile acid, chenodeoxycholic acid that has_material_basis_in homozygous or compound heterozygous mutation in the CYP27A1 gene, which encodes sterol 27-hydroxylase, on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:4810", "evidence": [ { "id": "4810", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4810" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:5041", "evidence": [ { "id": "5041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5041" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:893", "name": "Wilson disease", "description": "A metal metabolism disease that is characterized by excess copper stored in various body tissues, particularly the liver, brain, and corneas of the eyes.", "url": "https://disease-ontology.org/term/DOID:893", "evidence": [ { "id": "893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:893" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VE00", "url": "https://www.uniprot.org/uniprotkb/Q9VE00" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VE00", "url": "https://www.uniprot.org/uniprotkb/Q9VE00" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VE00", "url": "https://www.uniprot.org/uniprotkb/Q9VE00" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VE00", "url": "https://www.uniprot.org/uniprotkb/Q9VE00" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VE00", "url": "https://www.uniprot.org/uniprotkb/Q9VE00" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "Q9VE00", "url": "https://www.uniprot.org/uniprotkb/Q9VE00" } ], "pmid": "" } ], "biological_process": [ { "name": "response to insecticide", "id": "GO:0017085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017085", "evidence": [ { "database": "UniProtKB", "id": "Q9VE00", "url": "https://www.uniprot.org/uniprotkb/Q9VE00" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VE50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 232, "chemical_mass": 25562.0, "gene_names": "Gos28;CG7700;Dmel\\CG7700;FSG28;GOS28;Gos28;dGos28;dgos28;gos28", "protein_name": "Golgi SNAP receptor complex member 1", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "Golgi medial cisterna", "id": "GO:0005797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005797", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "Golgi trans cisterna", "id": "GO:0000138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000138", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" }, { "name": "inter-Golgi cisterna vesicle-mediated transport", "id": "GO:0048219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048219", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" } ], "molecular_function": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "Q9VE50", "url": "https://www.uniprot.org/uniprotkb/Q9VE50" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VE51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 684, "chemical_mass": 76826.0, "gene_names": "Cpsf73;CG7698;CPSF-73;CPSF73;Cpsf73;Dmel\\CG7698;cpsf-73;dCPSF-73", "protein_name": "Cleavage and polyadenylation specificity factor 73", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "pmid": "" }, { "name": "5'-3' RNA exonuclease activity", "id": "GO:0004534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004534", "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "pmid": "" } ], "cellular_component": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA 3'-end processing by stem-loop binding and cleavage", "id": "GO:0006398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006398", "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "pmid": "" }, { "name": "nuclear histone mRNA catabolic process", "id": "GO:0071045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071045", "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "pmid": "" }, { "name": "co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "id": "GO:0180010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180010", "evidence": [ { "database": "UniProtKB", "id": "Q9VE51", "url": "https://www.uniprot.org/uniprotkb/Q9VE51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VEF0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 430, "chemical_mass": 50479.0, "gene_names": "Odj;CG7357;Dmel\\CG7357;Dmel_CG7357;Odj", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VEF0", "url": "https://www.uniprot.org/uniprotkb/Q9VEF0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VEQ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VEQ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 32745.0, "gene_names": "EMC2B;CG3678;Dmel\\CG3678;Dmel_CG3678;EMC2B;RE62710p;emc2B", "protein_name": "ER membrane protein complex subunit 2", "disease": [], "cellular_component": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "Q9VEQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VEQ2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VEQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VEQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "Q9VEQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VEQ2" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "Q9VEQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VEQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VES8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VES8", "url": "https://www.uniprot.org/uniprotkb/Q9VES8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 278, "chemical_mass": 32034.0, "gene_names": "anon2A5;CG10340;Dmel\\CG10340;Dmel_CG10340;anon-EST:fe2A5;anon2A5", "protein_name": "ATP synthase mitochondrial F1 complex assembly factor 1", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VES8", "url": "https://www.uniprot.org/uniprotkb/Q9VES8" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VES8", "url": "https://www.uniprot.org/uniprotkb/Q9VES8" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "Q9VES8", "url": "https://www.uniprot.org/uniprotkb/Q9VES8" } ], "pmid": "" }, { "name": "mitochondrial proton-transporting ATP synthase complex assembly", "id": "GO:0033615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033615", "evidence": [ { "database": "UniProtKB", "id": "Q9VES8", "url": "https://www.uniprot.org/uniprotkb/Q9VES8" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-containing complex stabilizing activity", "id": "GO:0140777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140777", "evidence": [ { "database": "UniProtKB", "id": "Q9VES8", "url": "https://www.uniprot.org/uniprotkb/Q9VES8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VEU0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 362, "chemical_mass": 41634.0, "gene_names": "Gr89a;CG14901;Dmel\\CG14901;GR89a;Gr89a", "protein_name": "Putative gustatory receptor 89a", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of taste", "id": "GO:0050912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050912", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU0", "url": "https://www.uniprot.org/uniprotkb/Q9VEU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VEU5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 669, "chemical_mass": 75882.0, "gene_names": "Gyc89Db;CG14886;Dmel\\CG14886;Gyc-89Db;Gyc89Db", "protein_name": "Soluble guanylate cyclase 89Db", "disease": [], "molecular_function": [ { "name": "guanylate cyclase activity", "id": "GO:0004383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004383", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" } ], "cellular_component": [ { "name": "guanylate cyclase complex, soluble", "id": "GO:0008074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008074", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" } ], "biological_process": [ { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "response to reactive oxygen species", "id": "GO:0000302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000302", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "response to hyperoxia", "id": "GO:0055093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055093", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "nitric oxide-cGMP-mediated signaling", "id": "GO:0038060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038060", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" }, { "name": "response to oxygen levels", "id": "GO:0070482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070482", "evidence": [ { "database": "UniProtKB", "id": "Q9VEU5", "url": "https://www.uniprot.org/uniprotkb/Q9VEU5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VF59-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VF59", "url": "https://www.uniprot.org/uniprotkb/Q9VF59" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 241, "chemical_mass": 26866.0, "gene_names": "B9d1;B9D1;B9d1;CG14870;Dmel\\CG14870", "protein_name": "B9 domain-containing protein 1", "disease": [ { "disease_id": "DOID:0050778", "name": "Meckel syndrome", "description": "A ciliopathy that is characterized by renal cystic dysplasia, occipital encephalocele, polydactyly (post axial), hepatic developmental defects, and pulmonary hypoplasia.", "url": "https://disease-ontology.org/term/DOID:0050778", "evidence": [ { "id": "0050778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050778" } ], "weight": 0.0 }, { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 }, { "disease_id": "DOID:0110996", "name": "Joubert syndrome 27", "description": "A Joubert syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the B9D1 gene on chromosome 17p11.", "url": "https://disease-ontology.org/term/DOID:0110996", "evidence": [ { "id": "0110996", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110996" } ], "weight": 0.0 }, { "disease_id": "DOID:12712", "name": "nephronophthisis", "description": "A kidney disease that is characterized by a chronic tubulointerstitial nephritis that progress to terminal renal failure during the second decade (juvenile form) or before the age of 5 years (infantile form) resulting from dysfunction of ciliary proteins (ciliopathy).", "url": "https://disease-ontology.org/term/DOID:12712", "evidence": [ { "id": "12712", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12712" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VF59", "url": "https://www.uniprot.org/uniprotkb/Q9VF59" } ], "pmid": "" }, { "name": "ciliary transition zone assembly", "id": "GO:1905349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905349", "evidence": [ { "database": "UniProtKB", "id": "Q9VF59", "url": "https://www.uniprot.org/uniprotkb/Q9VF59" } ], "pmid": "" }, { "name": "Y-shaped link assembly", "id": "GO:1905350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905350", "evidence": [ { "database": "UniProtKB", "id": "Q9VF59", "url": "https://www.uniprot.org/uniprotkb/Q9VF59" } ], "pmid": "" } ], "cellular_component": [ { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "Q9VF59", "url": "https://www.uniprot.org/uniprotkb/Q9VF59" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "Q9VF59", "url": "https://www.uniprot.org/uniprotkb/Q9VF59" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VF78-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VF78", "url": "https://www.uniprot.org/uniprotkb/Q9VF78" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 710, "chemical_mass": 81136.0, "gene_names": "Cog2;CG6177;Cog2;Dmel\\CG6177;ldl-Cp;ldlCp", "protein_name": "Conserved oligomeric Golgi complex subunit 2", "disease": [ { "disease_id": "DOID:0070269", "name": "congenital disorder of glycosylation type IIq", "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the COG2 gene on chromosome 1q42.2.", "url": "https://disease-ontology.org/term/DOID:0070269", "evidence": [ { "id": "0070269", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070269" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VF78", "url": "https://www.uniprot.org/uniprotkb/Q9VF78" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "Q9VF78", "url": "https://www.uniprot.org/uniprotkb/Q9VF78" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VF78", "url": "https://www.uniprot.org/uniprotkb/Q9VF78" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9VF78", "url": "https://www.uniprot.org/uniprotkb/Q9VF78" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "Q9VF78", "url": "https://www.uniprot.org/uniprotkb/Q9VF78" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q9VF78", "url": "https://www.uniprot.org/uniprotkb/Q9VF78" } ], "pmid": "" }, { "name": "spermatid nucleus elongation", "id": "GO:0007290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007290", "evidence": [ { "database": "UniProtKB", "id": "Q9VF78", "url": "https://www.uniprot.org/uniprotkb/Q9VF78" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VF87-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1291, "chemical_mass": 149261.0, "gene_names": "Cyfip;CG4931;CYFIP1/2;CYFIP1;CYFIP;Cyfip;DSra-1;Dmel\\CG4931;PIR121/Sra-1;PIR121;Sra-1/CYFIP;Sra-1;Sra1/PIR121;Sra1;Sra;cyfip;dCYFIP1;dCYFIP;dCyfip;dSra;sra-1;sra1", "protein_name": "Cytoplasmic FMR1-interacting protein", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060393", "name": "chromosome 15q11.2 deletion syndrome", "description": "A chromosomal deletion syndrome that is characterized by intellectual disability, dysmorphic facies, psychiatric illness and autism spectrum disorder, has_material_basis_in autosomal dominant inheritance of partial deletion of the long arm of chromosome 15.", "url": "https://disease-ontology.org/term/DOID:0060393", "evidence": [ { "id": "0060393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060393" } ], "weight": 0.0 }, { "disease_id": "DOID:0080430", "name": "developmental and epileptic encephalopathy 65", "description": "A developmental and epileptic encephalopathy characterized by onset in the first months to years of life of various types of intractable seizures, severe to profound psychomotor developmental delay, and mild facial dysmorphism that has_material_basis_in heterozygous mutation in the CYFIP2 gene on chromosome 5q33.", "url": "https://disease-ontology.org/term/DOID:0080430", "evidence": [ { "id": "0080430", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080430" } ], "weight": 0.0 }, { "disease_id": "DOID:0111715", "name": "Schaaf-Yang syndrome", "description": "A syndrome characterized by delayed psychomotor development, impaired intellectual development, hypotonia, and behavioral abnormalities that has_material_basis_in heterozygous mutation in the maternally imprinted gene MAGEL2 on chromosome 15q11.2.", "url": "https://disease-ontology.org/term/DOID:0111715", "evidence": [ { "id": "0111715", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111715" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "SCAR complex", "id": "GO:0031209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031209", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "cell adhesion mediated by integrin", "id": "GO:0033627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033627", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034315", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "centripetally migrating follicle cell migration", "id": "GO:0060269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060269", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" }, { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "Q9VF87", "url": "https://www.uniprot.org/uniprotkb/Q9VF87" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VFH6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFH6", "url": "https://www.uniprot.org/uniprotkb/Q9VFH6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 818, "chemical_mass": 92782.0, "gene_names": "CG7886;Dmel\\CG7886;anon-WO0140519.200", "protein_name": "Protein Cep78 homolog", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9VFH6", "url": "https://www.uniprot.org/uniprotkb/Q9VFH6" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q9VFH6", "url": "https://www.uniprot.org/uniprotkb/Q9VFH6" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VFH6", "url": "https://www.uniprot.org/uniprotkb/Q9VFH6" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "Q9VFH6", "url": "https://www.uniprot.org/uniprotkb/Q9VFH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VFJ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VFJ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 492, "chemical_mass": 56534.0, "gene_names": "Cyp313a1;313a1p;313a1;CG3360;CYP313a1;Cyp313A1;Cyp313a1p;Cyp313a1;Cyp313a;Dmel\\CG3360", "protein_name": "Probable cytochrome P450 313a1", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VFJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VFJ0" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VFJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VFJ0" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VFJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VFJ0" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VFJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VFJ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VFJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VFJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VFP1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFP1", "url": "https://www.uniprot.org/uniprotkb/Q9VFP1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 508, "chemical_mass": 57384.0, "gene_names": "Cyp6d5;6d5;CG3050;CYP6D5;CYP6d5;Cyp6D5;Cyp6d5;Dmel\\CG3050;cyp6d5", "protein_name": "Probable cytochrome P450 6d5", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VFP1", "url": "https://www.uniprot.org/uniprotkb/Q9VFP1" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VFP1", "url": "https://www.uniprot.org/uniprotkb/Q9VFP1" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VFP1", "url": "https://www.uniprot.org/uniprotkb/Q9VFP1" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VFP1", "url": "https://www.uniprot.org/uniprotkb/Q9VFP1" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VFP1", "url": "https://www.uniprot.org/uniprotkb/Q9VFP1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VFR0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFR0", "url": "https://www.uniprot.org/uniprotkb/Q9VFR0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 297, "chemical_mass": 33429.0, "gene_names": "CG9286;Dmel\\CG9286", "protein_name": "Protein BCCIP homolog", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR0", "url": "https://www.uniprot.org/uniprotkb/Q9VFR0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase regulator activity", "id": "GO:0019887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019887", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR0", "url": "https://www.uniprot.org/uniprotkb/Q9VFR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VFR1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 214, "chemical_mass": 23831.0, "gene_names": "abitram;CG9288;Dmel\\CG9288;Dromel_CG9288_FBtr0082829_pyruvatekinasedomain_mORF", "protein_name": "Protein Abitram", "disease": [], "molecular_function": [ { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" }, { "name": "filopodium tip", "id": "GO:0032433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032433", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" } ], "biological_process": [ { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" }, { "name": "regulation of filopodium assembly", "id": "GO:0051489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051489", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "Q9VFR1", "url": "https://www.uniprot.org/uniprotkb/Q9VFR1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VG17-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG17", "url": "https://www.uniprot.org/uniprotkb/Q9VG17" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 510, "chemical_mass": 58790.0, "gene_names": "Cyp304a1;304a1;BcDNA:LP06355;CG7241;CYP304A1-Dm;CYP304A1;CYP304a1;Cyp304A1;Cyp304a1;Dmel\\CG7241", "protein_name": "Probable cytochrome P450 304a1", "disease": [ { "disease_id": "DOID:0050073", "name": "invasive aspergillosis", "description": "An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage.", "url": "https://disease-ontology.org/term/DOID:0050073", "evidence": [ { "id": "0050073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050073" } ], "weight": 0.0 }, { "disease_id": "DOID:0050083", "name": "Keshan disease", "description": "A nutritional deficiency that is disease characterized by a cardiomyopathy secondary to selenium deficiency.", "url": "https://disease-ontology.org/term/DOID:0050083", "evidence": [ { "id": "0050083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050083" } ], "weight": 0.0 }, { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050868", "name": "hepatocellular adenoma", "description": "A liver benign neoplasm that is located_in liver cells and that is composed_of epithelial tissue in which tumor cells form glands or glandlike structures.", "url": "https://disease-ontology.org/term/DOID:0050868", "evidence": [ { "id": "0050868", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050868" } ], "weight": 0.0 }, { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080665", "name": "warfarin resistance", "description": "An inherited metabolic disorder that is characterized by a high tolerance for the drug warfarin.", "url": "https://disease-ontology.org/term/DOID:0080665", "evidence": [ { "id": "0080665", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080665" } ], "weight": 0.0 }, { "disease_id": "DOID:1073", "name": "renal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1073", "evidence": [ { "id": "1073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1073" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain.", "url": "https://disease-ontology.org/term/DOID:10923", "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:13922", "name": "eosinophilic esophagitis", "description": "An esophagitis characterized by inflammation involving eosinophils located_in esophagus.", "url": "https://disease-ontology.org/term/DOID:13922", "evidence": [ { "id": "13922", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13922" } ], "weight": 0.0 }, { "disease_id": "DOID:14067", "name": "Plasmodium falciparum malaria", "description": "A malaria described as a severe form of the disease caused by a parasite Plasmodium falciparum, which is marked by irrregular recurrence of paroxysms and prolonged or continuous fever.", "url": "https://disease-ontology.org/term/DOID:14067", "evidence": [ { "id": "14067", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14067" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2044", "name": "drug-induced hepatitis", "description": "", "url": "https://disease-ontology.org/term/DOID:2044", "evidence": [ { "id": "2044", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2044" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:4661", "name": "multiple chemical sensitivity", "description": "A syndrome that is an adverse physical reaction to low levels of many common chemicals.", "url": "https://disease-ontology.org/term/DOID:4661", "evidence": [ { "id": "4661", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4661" } ], "weight": 0.0 }, { "disease_id": "DOID:5520", "name": "head and neck squamous cell carcinoma", "description": "A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.", "url": "https://disease-ontology.org/term/DOID:5520", "evidence": [ { "id": "5520", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5520" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:750", "name": "peptic ulcer disease", "description": "", "url": "https://disease-ontology.org/term/DOID:750", "evidence": [ { "id": "750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:750" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 }, { "disease_id": "DOID:9993", "name": "hypoglycemia", "description": "A glucose metabolism disease that is characterized by abnormally low levels of blood glucose.", "url": "https://disease-ontology.org/term/DOID:9993", "evidence": [ { "id": "9993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9993" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VG17", "url": "https://www.uniprot.org/uniprotkb/Q9VG17" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VG17", "url": "https://www.uniprot.org/uniprotkb/Q9VG17" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VG17", "url": "https://www.uniprot.org/uniprotkb/Q9VG17" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VG17", "url": "https://www.uniprot.org/uniprotkb/Q9VG17" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VG17", "url": "https://www.uniprot.org/uniprotkb/Q9VG17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VG38-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 468, "chemical_mass": 52788.0, "gene_names": "Su(fu);CG6054;Dmel\\CG6054;Dmel_CG6054;SU(FU);SUFU;Su(Fu);Su(fu);SuFu;Sufu;d Sufu;dSufu;su(fu);sufu", "protein_name": "Suppressor of fused homolog", "disease": [ { "disease_id": "DOID:0050902", "name": "medulloblastoma", "description": "An infratentorial cancer that is located_in the lower part of the brain and is a type of primitive neuroectodermal tumor.", "url": "https://disease-ontology.org/term/DOID:0050902", "evidence": [ { "id": "0050902", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050902" } ], "weight": 0.0 }, { "disease_id": "DOID:0060071", "name": "pre-malignant neoplasm", "description": "A disease of cellular proliferation that results in abnormal growths in the body, which do not invade or destroy the surrounding tissue but, given enough time, will transform into a cancer.", "url": "https://disease-ontology.org/term/DOID:0060071", "evidence": [ { "id": "0060071", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060071" } ], "weight": 0.0 }, { "disease_id": "DOID:0070366", "name": "nevoid basal cell carcinoma syndrome 2", "description": "A nevoid basal cell carcinoma syndrome that has_material_basis_in heterozygous mutation in the SUFU gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0070366", "evidence": [ { "id": "0070366", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070366" } ], "weight": 0.0 }, { "disease_id": "DOID:0080278", "name": "Joubert syndrome 32", "description": "A Joubert syndrome that has_material_basis_in homozygous mutation in the SUFU gene on chromosome 10q24.", "url": "https://disease-ontology.org/term/DOID:0080278", "evidence": [ { "id": "0080278", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080278" } ], "weight": 0.0 }, { "disease_id": "DOID:2512", "name": "nevoid basal cell carcinoma syndrome", "description": "A syndrome characterized by multiple early-onset basal cell carcinoma, multiple jaw keratocysts and skeletal abnormalities.", "url": "https://disease-ontology.org/term/DOID:2512", "evidence": [ { "id": "2512", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2512" } ], "weight": 0.0 }, { "disease_id": "DOID:3073", "name": "brain glioblastoma multiforme", "description": "A brain glioma that has_material_basis_in abnormally proliferating cells derives_from glial cells, has_symptom seizure, headaches, nausea and vomiting, memory loss, changes to personality, mood or concentration; and localized neurological problems.", "url": "https://disease-ontology.org/term/DOID:3073", "evidence": [ { "id": "3073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3073" } ], "weight": 0.0 }, { "disease_id": "DOID:4586", "name": "familial meningioma", "description": "", "url": "https://disease-ontology.org/term/DOID:4586", "evidence": [ { "id": "4586", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4586" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" }, { "name": "molecular sequestering activity", "id": "GO:0140313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140313", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "Q9VG38", "url": "https://www.uniprot.org/uniprotkb/Q9VG38" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VG55-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 191, "chemical_mass": 20623.0, "gene_names": "Hug;CG6371;Dmel\\CG6371;Drm-MT2;Drm-PK-2;HUGgamma;HUG;Hug-PK;Hug-gamma;Hugin PK;Hugin-PK-2;Hug;PK-2;hug gamma;hug-1;hug-2;hug-PK;hug-gamma;huggamma;hugg;huginPK;hugin;hug;pyrokinin/PBAN-like", "protein_name": "Protein hugin", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" } ], "biological_process": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" }, { "name": "ecdysis, chitin-based cuticle", "id": "GO:0018990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018990", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" }, { "name": "larval feeding behavior", "id": "GO:0030536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030536", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" } ], "molecular_function": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" }, { "name": "ecdysis-triggering hormone activity", "id": "GO:0008255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008255", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" }, { "name": "myostimulatory hormone activity", "id": "GO:0016084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016084", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" }, { "name": "neuropeptide activity", "id": "GO:0160041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160041", "evidence": [ { "database": "UniProtKB", "id": "Q9VG55", "url": "https://www.uniprot.org/uniprotkb/Q9VG55" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VG73-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 396, "chemical_mass": 43657.0, "gene_names": "CG5641;Dmel\\CG5641", "protein_name": "Interleukin enhancer-binding factor 2 homolog", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VG73", "url": "https://www.uniprot.org/uniprotkb/Q9VG73" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VG73-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Thr67", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 67, "start_aa": "Thr", "end_pos": 67, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VG92-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG92", "url": "https://www.uniprot.org/uniprotkb/Q9VG92" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 212, "chemical_mass": 24179.0, "gene_names": "GstD8;CG4421;DmGST27;DmGSTD8;Dmel\\CG4421;Dmel_CG4421;GST D27;GSTD8;GST;GstD27;GstD8;Gst;gstD27;gstD8;gstd8;gst", "protein_name": "", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "Q9VG92", "url": "https://www.uniprot.org/uniprotkb/Q9VG92" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "Q9VG92", "url": "https://www.uniprot.org/uniprotkb/Q9VG92" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VG92", "url": "https://www.uniprot.org/uniprotkb/Q9VG92" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "Q9VG92", "url": "https://www.uniprot.org/uniprotkb/Q9VG92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VG95-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG95", "url": "https://www.uniprot.org/uniprotkb/Q9VG95" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 216, "chemical_mass": 24713.0, "gene_names": "GstD5;CG12242;D5;DmGST24;DmGSTD5;Dmel\\CG12242;GSTD5-5;GSTD5;GSTd5;GST;Gst D5;GstD24;GstD5;Gst;dGSTT4;gstD24;gstD5;gstd5;gst", "protein_name": "Glutathione S-transferase D5", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "Q9VG95", "url": "https://www.uniprot.org/uniprotkb/Q9VG95" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VG95", "url": "https://www.uniprot.org/uniprotkb/Q9VG95" } ], "pmid": "" } ], "biological_process": [ { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "Q9VG95", "url": "https://www.uniprot.org/uniprotkb/Q9VG95" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "Q9VG95", "url": "https://www.uniprot.org/uniprotkb/Q9VG95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VG98-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG98", "url": "https://www.uniprot.org/uniprotkb/Q9VG98" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 215, "chemical_mass": 24535.0, "gene_names": "GstD2;CG4181;DmGST21;DmGSTD2;Dmel\\CG4181;GST D2;GST-D2;GSTD2-2;GSTD2;GSTd2;GST;Gst D2;GstD21;GstD2;Gstd21;Gst;gst D21;gstD21;gstD2;gstd21;gstd2;gst", "protein_name": "Glutathione S-transferase D2", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "Q9VG98", "url": "https://www.uniprot.org/uniprotkb/Q9VG98" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "Q9VG98", "url": "https://www.uniprot.org/uniprotkb/Q9VG98" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VG98", "url": "https://www.uniprot.org/uniprotkb/Q9VG98" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "Q9VG98", "url": "https://www.uniprot.org/uniprotkb/Q9VG98" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGB4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGB4", "url": "https://www.uniprot.org/uniprotkb/Q9VGB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 493, "chemical_mass": 56651.0, "gene_names": "Cyp313a2;313a2;CG10094;CYP313A2;Cyp313A2;Cyp313a2;Dmel\\CG10094", "protein_name": "Probable cytochrome P450 313a2", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB4", "url": "https://www.uniprot.org/uniprotkb/Q9VGB4" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB4", "url": "https://www.uniprot.org/uniprotkb/Q9VGB4" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB4", "url": "https://www.uniprot.org/uniprotkb/Q9VGB4" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB4", "url": "https://www.uniprot.org/uniprotkb/Q9VGB4" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB4", "url": "https://www.uniprot.org/uniprotkb/Q9VGB4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGB5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGB5", "url": "https://www.uniprot.org/uniprotkb/Q9VGB5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 487, "chemical_mass": 55618.0, "gene_names": "Cyp313a5;313a5;CG15807;CYP313a5;Cyp313a5;Dmel\\CG15807", "protein_name": "Probable cytochrome P450 313a5", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB5", "url": "https://www.uniprot.org/uniprotkb/Q9VGB5" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB5", "url": "https://www.uniprot.org/uniprotkb/Q9VGB5" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB5", "url": "https://www.uniprot.org/uniprotkb/Q9VGB5" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB5", "url": "https://www.uniprot.org/uniprotkb/Q9VGB5" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB5", "url": "https://www.uniprot.org/uniprotkb/Q9VGB5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VGB5-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Tyr223", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB5", "url": "https://www.uniprot.org/uniprotkb/Q9VGB5" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VGB5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VGB5" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGC1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGC1", "url": "https://www.uniprot.org/uniprotkb/Q9VGC1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 421, "chemical_mass": 45932.0, "gene_names": "Rsbp15;CG10014;Dmel\\CG10014;Dmel_CG10014;RSBP15;Rsbp15;rsbp15", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC1", "url": "https://www.uniprot.org/uniprotkb/Q9VGC1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC1", "url": "https://www.uniprot.org/uniprotkb/Q9VGC1" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC1", "url": "https://www.uniprot.org/uniprotkb/Q9VGC1" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC1", "url": "https://www.uniprot.org/uniprotkb/Q9VGC1" } ], "pmid": "" }, { "name": "sperm individualization complex", "id": "GO:0070864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070864", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC1", "url": "https://www.uniprot.org/uniprotkb/Q9VGC1" } ], "pmid": "" } ], "biological_process": [ { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC1", "url": "https://www.uniprot.org/uniprotkb/Q9VGC1" } ], "pmid": "" }, { "name": "protein localization to motile cilium", "id": "GO:0120229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120229", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC1", "url": "https://www.uniprot.org/uniprotkb/Q9VGC1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VGC1-1", "start_pos": "300", "end_pos": "300", "site_lbl": "Thr300", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 300, "start_aa": "Thr", "end_pos": 300, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr300", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VGC1-1", "start_pos": "402", "end_pos": "402", "site_lbl": "Thr402", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 402, "start_aa": "Thr", "end_pos": 402, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr402", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGC7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 551, "chemical_mass": 62749.0, "gene_names": "eIF3d2;149735_at;CG4810;Dmel\\CG4810;eIF3-S7-2;eIF3-S7;eIF3d2", "protein_name": "Eukaryotic translation initiation factor 3 subunit D-2", "disease": [], "biological_process": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" }, { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" }, { "name": "cap-dependent translational initiation", "id": "GO:0002191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002191", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" }, { "name": "mRNA cap binding", "id": "GO:0098808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098808", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q9VGC7", "url": "https://www.uniprot.org/uniprotkb/Q9VGC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGJ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 195, "chemical_mass": 22124.0, "gene_names": "fer3;BcDNA:LD04689;CG6913;Dmel\\CG6913;Dnato3;Fer3;Nato3;Ntwist;bHLHa32;nato3", "protein_name": "Protein Fer3", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "Q9VGJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGJ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGN7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 583, "chemical_mass": 66867.0, "gene_names": "Exd2;CG6744;Dmel\\CG6744;EXD2;Exd2;dEXD2", "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "disease": [ { "disease_id": "DOID:5688", "name": "Werner syndrome", "description": "A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8.", "url": "https://disease-ontology.org/term/DOID:5688", "evidence": [ { "id": "5688", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5688" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" }, { "name": "3'-5' exonuclease activity", "id": "GO:0008408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008408", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" } ], "biological_process": [ { "name": "somatic cell DNA recombination", "id": "GO:0016444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016444", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" }, { "name": "positive regulation of formation of translation preinitiation complex", "id": "GO:1901195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901195", "evidence": [ { "database": "UniProtKB", "id": "Q9VGN7", "url": "https://www.uniprot.org/uniprotkb/Q9VGN7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGQ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 86, "chemical_mass": 10115.0, "gene_names": "Dph3;CG14701;Dmel\\CG14701;Dph3;Kti11", "protein_name": "Diphthamide biosynthesis protein 3", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "pmid": "" }, { "name": "iron chaperone activity", "id": "GO:0034986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034986", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "pmid": "" }, { "name": "tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation", "id": "GO:0002926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002926", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGZ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 583, "chemical_mass": 65829.0, "gene_names": "149631_at;CG6345;Dmel\\CG6345", "protein_name": "CDK5RAP1-like protein", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" }, { "name": "tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity", "id": "GO:0035597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035597", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0000079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000079", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" }, { "name": "RNA modification", "id": "GO:0009451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009451", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" }, { "name": "mitochondrial tRNA modification", "id": "GO:0070900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070900", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ1", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGZ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 233, "chemical_mass": 25738.0, "gene_names": "Rrp46;CG4043;Dmel\\CG4043;Dmel_CG4043;Rrp46;dRrp46;rrp46", "protein_name": "", "disease": [], "biological_process": [ { "name": "nuclear mRNA surveillance", "id": "GO:0071028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071028", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "U4 snRNA 3'-end processing", "id": "GO:0034475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034475", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "poly(A)-dependent snoRNA 3'-end processing", "id": "GO:0071051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071051", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "nuclear exosome (RNase complex)", "id": "GO:0000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000176", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "cytoplasmic exosome (RNase complex)", "id": "GO:0000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000177", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" }, { "name": "exosome (RNase complex)", "id": "GO:0000178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000178", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VGZ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 698, "chemical_mass": 75106.0, "gene_names": "cwo;AAF24476.1;CG17100;CWO;Cwo;Dmel\\CG17100;GM05287;bHLHe49;cwo;dcwo;mel_cwo", "protein_name": "Transcription factor cwo", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9VGZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VGZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VH36-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 585, "chemical_mass": 66453.0, "gene_names": "ohgt;CG3925;Crbn;Dmel\\CG3925;crbn;ohgt", "protein_name": "Protein cereblon", "disease": [ { "disease_id": "DOID:0060308", "name": "autosomal recessive intellectual developmental disorder", "description": "A intellectual disability characterized by an autosomal recessive inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0060308", "evidence": [ { "id": "0060308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060308" } ], "weight": 0.0 }, { "disease_id": "DOID:0081178", "name": "autosomal recessive intellectual developmental disorder 2", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the gene encoding cereblon (CRBN) on chromosome 3p26.", "url": "https://disease-ontology.org/term/DOID:0081178", "evidence": [ { "id": "0081178", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081178" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Cul4A-RING E3 ubiquitin ligase complex", "id": "GO:0031464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031464", "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "pmid": "" }, { "name": "positive regulation of neuromuscular synaptic transmission", "id": "GO:1900075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900075", "evidence": [ { "database": "UniProtKB", "id": "Q9VH36", "url": "https://www.uniprot.org/uniprotkb/Q9VH36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VH45-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH45", "url": "https://www.uniprot.org/uniprotkb/Q9VH45" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 173, "chemical_mass": 19063.0, "gene_names": "Dmel\\CG5359;BcDNA:RE37471;CG5359;Dmel\\CG5359;Dmel_CG5359", "protein_name": "", "disease": [ { "disease_id": "DOID:0050592", "name": "asphyxiating thoracic dystrophy", "description": "A bone development disease characterized by skeletal abnormalities and resulting in difficulty in breathing caused by mutations that result in ciliopathy.", "url": "https://disease-ontology.org/term/DOID:0050592", "evidence": [ { "id": "0050592", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050592" } ], "weight": 0.0 }, { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 }, { "disease_id": "DOID:0111910", "name": "spermatogenic failure", "description": "A male infertility characterized by disruption of the process of sperm development from diploid cells into mature haploid spermatozoa.", "url": "https://disease-ontology.org/term/DOID:0111910", "evidence": [ { "id": "0111910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111910" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VH45", "url": "https://www.uniprot.org/uniprotkb/Q9VH45" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "Q9VH45", "url": "https://www.uniprot.org/uniprotkb/Q9VH45" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q9VH45", "url": "https://www.uniprot.org/uniprotkb/Q9VH45" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VH45", "url": "https://www.uniprot.org/uniprotkb/Q9VH45" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "Q9VH45", "url": "https://www.uniprot.org/uniprotkb/Q9VH45" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "Q9VH45", "url": "https://www.uniprot.org/uniprotkb/Q9VH45" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VH48-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 530, "chemical_mass": 59728.0, "gene_names": "Art4;Art4;CARM1;CG5358;Carmer;DART4;Dart4;Dmel\\CG5358;PRMT4;dArt 4", "protein_name": "Probable histone-arginine methyltransferase CARMER", "disease": [ { "disease_id": "DOID:0050868", "name": "hepatocellular adenoma", "description": "A liver benign neoplasm that is located_in liver cells and that is composed_of epithelial tissue in which tumor cells form glands or glandlike structures.", "url": "https://disease-ontology.org/term/DOID:0050868", "evidence": [ { "id": "0050868", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050868" } ], "weight": 0.0 }, { "disease_id": "DOID:0060075", "name": "estrogen-receptor positive breast cancer", "description": "A breast cancer that is characterized by the presence of estrogen receptors.", "url": "https://disease-ontology.org/term/DOID:0060075", "evidence": [ { "id": "0060075", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060075" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8634", "name": "prostate carcinoma in situ", "description": "An in situ carcinoma that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:8634", "evidence": [ { "id": "8634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8634" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "histone methyltransferase complex", "id": "GO:0035097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "positive regulation of ecdysone receptor signaling pathway", "id": "GO:0120142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120142", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "protein-arginine omega-N monomethyltransferase activity", "id": "GO:0035241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035241", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "histone H3R2 methyltransferase activity", "id": "GO:0070611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070611", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" }, { "name": "histone H3R17 methyltransferase activity", "id": "GO:0035642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035642", "evidence": [ { "database": "UniProtKB", "id": "Q9VH48", "url": "https://www.uniprot.org/uniprotkb/Q9VH48" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VH58-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 257, "chemical_mass": 29923.0, "gene_names": "eloF;CG16905;Dmel\\CG16905;EloF;eloF", "protein_name": "Very long chain fatty acid elongase F", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" }, { "name": "fatty acid elongation", "id": "GO:0030497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030497", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" }, { "name": "fatty acid elongation, monounsaturated fatty acid", "id": "GO:0034625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034625", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" }, { "name": "fatty acid elongation, polyunsaturated fatty acid", "id": "GO:0034626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034626", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" }, { "name": "fatty acid elongation, saturated fatty acid", "id": "GO:0019367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019367", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" }, { "name": "pheromone metabolic process", "id": "GO:0042810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042810", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" }, { "name": "courtship behavior", "id": "GO:0007619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007619", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acid elongase activity", "id": "GO:0009922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009922", "evidence": [ { "database": "UniProtKB", "id": "Q9VH58", "url": "https://www.uniprot.org/uniprotkb/Q9VH58" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VH78-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH78", "url": "https://www.uniprot.org/uniprotkb/Q9VH78" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 678, "chemical_mass": 76553.0, "gene_names": "Alg12;Alg12;CG8412;Dmel\\CG8412;dAlg12", "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "disease": [ { "disease_id": "DOID:0050570", "name": "congenital disorder of glycosylation type I", "description": "A congenital disorder of glycosylation characterized by under-glycosylated serum glycoproteins.", "url": "https://disease-ontology.org/term/DOID:0050570", "evidence": [ { "id": "0050570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050570" } ], "weight": 0.0 }, { "disease_id": "DOID:0080559", "name": "congenital disorder of glycosylation Ig", "description": "A congenital disorder of glycosylation I that is characterized by facial dysmorphism (prominent forehead, large ears, thin upper lip), generalized hypotonia, feeding difficulties, moderate to severe developmental delay, progressive microcephaly, frequent upper respiratory tract infections due to impaired immunity with decreased immunoglobulin levels, and decreased coagulation factors and has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding dolichyl-P-mannose:Man-7-GlcNAc-2-PP-dolichyl-alpha-6-mannosyltransferase on chromosome 22q13.", "url": "https://disease-ontology.org/term/DOID:0080559", "evidence": [ { "id": "0080559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080559" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VH78", "url": "https://www.uniprot.org/uniprotkb/Q9VH78" } ], "pmid": "" } ], "biological_process": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "Q9VH78", "url": "https://www.uniprot.org/uniprotkb/Q9VH78" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "Q9VH78", "url": "https://www.uniprot.org/uniprotkb/Q9VH78" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-1,6-mannosyltransferase activity", "id": "GO:0000009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000009", "evidence": [ { "database": "UniProtKB", "id": "Q9VH78", "url": "https://www.uniprot.org/uniprotkb/Q9VH78" } ], "pmid": "" }, { "name": "dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity", "id": "GO:0052917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052917", "evidence": [ { "database": "UniProtKB", "id": "Q9VH78", "url": "https://www.uniprot.org/uniprotkb/Q9VH78" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VH89-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 857, "chemical_mass": 96513.0, "gene_names": "dmt;0481/03;CG8374;Dmel\\CG8374;Dmt;anon-WO0118547.317;aul;dmt;s048103", "protein_name": "Protein dalmatian", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "peripheral nervous system development", "id": "GO:0007422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007422", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "cellular response to radiation", "id": "GO:0071478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071478", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "salivary gland development", "id": "GO:0007431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007431", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "trachea development", "id": "GO:0060438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060438", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" }, { "name": "primary branching, open tracheal system", "id": "GO:0007428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007428", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VH89-1", "start_pos": "608", "end_pos": "608", "site_lbl": "Thr608", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 608, "start_aa": "Thr", "end_pos": 608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr608", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VH89-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Ser173", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VH89", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VH89" } ] } ] }, { "uniprot_canonical_ac": "Q9VH89-1", "start_pos": "175", "end_pos": "175", "site_lbl": "Ser175", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VH89", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VH89" } ] } ] }, { "uniprot_canonical_ac": "Q9VH89-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VH89", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VH89" } ] } ] }, { "uniprot_canonical_ac": "Q9VH89-1", "start_pos": "222", "end_pos": "222", "site_lbl": "Ser222", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VH89", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VH89" } ] } ] }, { "uniprot_canonical_ac": "Q9VH89-1", "start_pos": "405", "end_pos": "405", "site_lbl": "Ser405", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VH89", "url": "https://www.uniprot.org/uniprotkb/Q9VH89" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VH89", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VH89" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VHG6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHG6", "url": "https://www.uniprot.org/uniprotkb/Q9VHG6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 195, "chemical_mass": 21939.0, "gene_names": "Ibf2;CG9740;Dmel\\CG9740;Dmel_CG9740;Ibf2;Ibf", "protein_name": "", "disease": [], "molecular_function": [ { "name": "chromatin insulator sequence binding", "id": "GO:0043035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043035", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG6", "url": "https://www.uniprot.org/uniprotkb/Q9VHG6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG6", "url": "https://www.uniprot.org/uniprotkb/Q9VHG6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG6", "url": "https://www.uniprot.org/uniprotkb/Q9VHG6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG6", "url": "https://www.uniprot.org/uniprotkb/Q9VHG6" } ], "pmid": "" }, { "name": "heterochromatin boundary formation", "id": "GO:0033696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033696", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG6", "url": "https://www.uniprot.org/uniprotkb/Q9VHG6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VHH7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHH7", "url": "https://www.uniprot.org/uniprotkb/Q9VHH7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 337, "chemical_mass": 37576.0, "gene_names": "Ada;ADA;Ada;CG11994;DmADA;Dmel\\CG11994;DrosADA;ada;dADA", "protein_name": "Adenosine deaminase-like protein", "disease": [], "molecular_function": [ { "name": "adenosine deaminase activity", "id": "GO:0004000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004000", "evidence": [ { "database": "UniProtKB", "id": "Q9VHH7", "url": "https://www.uniprot.org/uniprotkb/Q9VHH7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VHH7", "url": "https://www.uniprot.org/uniprotkb/Q9VHH7" } ], "pmid": "" }, { "name": "N6-methyl-AMP deaminase activity", "id": "GO:0062154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062154", "evidence": [ { "database": "UniProtKB", "id": "Q9VHH7", "url": "https://www.uniprot.org/uniprotkb/Q9VHH7" } ], "pmid": "" } ], "biological_process": [ { "name": "adenosine catabolic process", "id": "GO:0006154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006154", "evidence": [ { "database": "UniProtKB", "id": "Q9VHH7", "url": "https://www.uniprot.org/uniprotkb/Q9VHH7" } ], "pmid": "" }, { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "Q9VHH7", "url": "https://www.uniprot.org/uniprotkb/Q9VHH7" } ], "pmid": "" }, { "name": "inosine biosynthetic process", "id": "GO:0046103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046103", "evidence": [ { "database": "UniProtKB", "id": "Q9VHH7", "url": "https://www.uniprot.org/uniprotkb/Q9VHH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VHN1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 96, "chemical_mass": 10957.0, "gene_names": "Cks85A;BcDNA:GM01344;CG9790;Cks85A;Cks;Dmel\\CG9790;Dmel_CG9790;cks85A", "protein_name": "Cyclin-dependent kinases regulatory subunit", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" }, { "name": "endomitotic cell cycle", "id": "GO:0007113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007113", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activator activity", "id": "GO:0061575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061575", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" } ], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "Q9VHN1", "url": "https://www.uniprot.org/uniprotkb/Q9VHN1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VHR6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 523, "chemical_mass": 56927.0, "gene_names": "Atg13;ATG13;Atg13;BcDNA:HL01508;CG7331;Dmel\\CG7331;atg13;dAtg13", "protein_name": "Autophagy-related protein 13 homolog", "disease": [], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "intestinal epithelial structure maintenance", "id": "GO:0060729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060729", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "larval midgut cell programmed cell death", "id": "GO:0035096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035096", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "positive regulation of nurse cell apoptotic process", "id": "GO:0045850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045850", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" }, { "name": "Atg1/ULK1 kinase complex", "id": "GO:1990316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990316", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase regulator activity", "id": "GO:0019887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019887", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VHR6-1", "start_pos": "214", "end_pos": "214", "site_lbl": "Thr214", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 214, "start_aa": "Thr", "end_pos": 214, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr214", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR6-1", "start_pos": "463", "end_pos": "463", "site_lbl": "Thr463", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 463, "start_aa": "Thr", "end_pos": 463, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr463", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR6-1", "start_pos": "227", "end_pos": "227", "site_lbl": "Ser227", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VHR6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VHR6" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR6-1", "start_pos": "238", "end_pos": "238", "site_lbl": "Thr238", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VHR6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VHR6" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR6-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VHR6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VHR6" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR6-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR6", "url": "https://www.uniprot.org/uniprotkb/Q9VHR6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VHR6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VHR6" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VHS7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHS7", "url": "https://www.uniprot.org/uniprotkb/Q9VHS7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 392, "chemical_mass": 42935.0, "gene_names": "Coq2;CG9613;COQ2;Coq2;Dmel\\CG9613;coq2;sbo", "protein_name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "disease": [ { "disease_id": "DOID:0050730", "name": "coenzyme Q10 deficiency disease", "description": "A mitochondrial metabolism disease that is characterized by a deficiency of CoQ10 resulting from reduced biosynthesis.", "url": "https://disease-ontology.org/term/DOID:0050730", "evidence": [ { "id": "0050730", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050730" } ], "weight": 0.0 }, { "disease_id": "DOID:0070238", "name": "primary coenzyme Q10 deficiency 1", "description": "A primary coenzyme Q10 deficiency that has_material_basis_in an autosomal recessive mutation of the COQ2 gene on chromosome 4q21.22-q21.23.", "url": "https://disease-ontology.org/term/DOID:0070238", "evidence": [ { "id": "0070238", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070238" } ], "weight": 0.0 }, { "disease_id": "DOID:10603", "name": "glucose intolerance", "description": "", "url": "https://disease-ontology.org/term/DOID:10603", "evidence": [ { "id": "10603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10603" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:4752", "name": "multiple system atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:4752", "evidence": [ { "id": "4752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4752" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VHS7", "url": "https://www.uniprot.org/uniprotkb/Q9VHS7" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "Q9VHS7", "url": "https://www.uniprot.org/uniprotkb/Q9VHS7" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "Q9VHS7", "url": "https://www.uniprot.org/uniprotkb/Q9VHS7" } ], "pmid": "" }, { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "Q9VHS7", "url": "https://www.uniprot.org/uniprotkb/Q9VHS7" } ], "pmid": "" }, { "name": "defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "Q9VHS7", "url": "https://www.uniprot.org/uniprotkb/Q9VHS7" } ], "pmid": "" }, { "name": "isoprenoid biosynthetic process", "id": "GO:0008299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008299", "evidence": [ { "database": "UniProtKB", "id": "Q9VHS7", "url": "https://www.uniprot.org/uniprotkb/Q9VHS7" } ], "pmid": "" } ], "molecular_function": [ { "name": "4-hydroxybenzoate polyprenyltransferase activity", "id": "GO:0008412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008412", "evidence": [ { "database": "UniProtKB", "id": "Q9VHS7", "url": "https://www.uniprot.org/uniprotkb/Q9VHS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VHT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 337, "chemical_mass": 38107.0, "gene_names": "Gfr;CG9620;Dmel\\CG9620;Gfr;Nac;gfr;nac", "protein_name": "GDP-fucose transporter, Golgi", "disease": [ { "disease_id": "DOID:0050571", "name": "congenital disorder of glycosylation type II", "description": "A congenital disorder of glycosylation that involves malfunctioning trimming or processing of the protein-bound oligosaccharide chain.", "url": "https://disease-ontology.org/term/DOID:0050571", "evidence": [ { "id": "0050571", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050571" } ], "weight": 0.0 }, { "disease_id": "DOID:0070255", "name": "congenital disorder of glycosylation type IIc", "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the SLC35C1 gene on chromosome 11p11.2.", "url": "https://disease-ontology.org/term/DOID:0070255", "evidence": [ { "id": "0070255", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070255" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" } ], "pmid": "" }, { "name": "Golgi-associated vesicle", "id": "GO:0005798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005798", "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" } ], "pmid": "" } ], "molecular_function": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" } ], "pmid": "" }, { "name": "GDP-fucose transmembrane transporter activity", "id": "GO:0005457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005457", "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" } ], "pmid": "" } ], "biological_process": [ { "name": "GDP-fucose transmembrane transport", "id": "GO:0015783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015783", "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" } ], "pmid": "" }, { "name": "GDP-fucose import into Golgi lumen", "id": "GO:0036085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036085", "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VHT4-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Ser29", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "L", "comment": "In nac1; abolishes GDP-fucose transport into the Golgi lumen. Shows lack of both core alpha-1,3- and alpha-1,6-linked fucose residues on N-glycans. Reduces neural expression of the HRP epitope. Does not affect subcellular localization to the Golgi apparatus.", "evidence": [ { "database": "UniProtKB", "id": "Q9VHT4", "url": "https://www.uniprot.org/uniprotkb/Q9VHT4" }, { "database": "PubMed", "id": "22745127", "url": "https://glygen.org/publication/PubMed/22745127" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VHU1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHU1", "url": "https://www.uniprot.org/uniprotkb/Q9VHU1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 613, "chemical_mass": 69084.0, "gene_names": "CG9630;DDX55;DmRH16;Dmel\\CG9630;cg9630", "protein_name": "Probable ATP-dependent RNA helicase DDX55 homolog", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU1", "url": "https://www.uniprot.org/uniprotkb/Q9VHU1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU1", "url": "https://www.uniprot.org/uniprotkb/Q9VHU1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU1", "url": "https://www.uniprot.org/uniprotkb/Q9VHU1" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU1", "url": "https://www.uniprot.org/uniprotkb/Q9VHU1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU1", "url": "https://www.uniprot.org/uniprotkb/Q9VHU1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU1", "url": "https://www.uniprot.org/uniprotkb/Q9VHU1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VIK2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 674, "chemical_mass": 76193.0, "gene_names": "CarT;38E.10;CG9317;CarT;Cart;Dmel\\CG9317;carT;cart", "protein_name": "Carcinine transporter", "disease": [ { "disease_id": "DOID:1074", "name": "kidney failure", "description": "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood.", "url": "https://disease-ontology.org/term/DOID:1074", "evidence": [ { "id": "1074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1074" } ], "weight": 0.0 }, { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 }, { "disease_id": "DOID:1852", "name": "intrahepatic cholestasis", "description": "A cholestasis characterized by impairment of the bile flow caused by obstruction located_in liver.", "url": "https://disease-ontology.org/term/DOID:1852", "evidence": [ { "id": "1852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1852" } ], "weight": 0.0 }, { "disease_id": "DOID:1920", "name": "hyperuricemia", "description": "An acquired metabolic disease that has_material_basis_in an abnormally high level of uric acid in the blood.", "url": "https://disease-ontology.org/term/DOID:1920", "evidence": [ { "id": "1920", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1920" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "neurotransmitter transmembrane transporter activity", "id": "GO:0005326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005326", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" }, { "name": "carcinine transmembrane transporter activity", "id": "GO:1905131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905131", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" } ], "biological_process": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" }, { "name": "neurotransmitter uptake", "id": "GO:0001504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001504", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" }, { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" }, { "name": "positive phototaxis", "id": "GO:0046956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046956", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" }, { "name": "carcinine import across plasma membrane", "id": "GO:1905130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905130", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK2", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VIK2-1", "start_pos": "122", "end_pos": "122", "site_lbl": "Asn122", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 122, "start_aa": "Asn", "end_pos": 122, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn122", "evidence": [ { "id": "Q9VIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VIK2-1", "start_pos": "141", "end_pos": "141", "site_lbl": "Asn141", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 141, "start_aa": "Asn", "end_pos": 141, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn141", "evidence": [ { "id": "Q9VIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VIK2-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Asn156", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 156, "start_aa": "Asn", "end_pos": 156, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn156", "evidence": [ { "id": "Q9VIK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIK2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VIK2-1", "start_pos": "179", "end_pos": "179", "site_lbl": "Thr179", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VIL0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1320, "chemical_mass": 145958.0, "gene_names": "brun;38D.28;CG2478;Dmel\\CG2478;TRAPPC9;brun;bru;dTRAPPC9", "protein_name": "Protein brunelleschi", "disease": [ { "disease_id": "DOID:0081098", "name": "autosomal recessive intellectual developmental disorder 13", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the TRAPPC9 gene on chromosome 8q24.", "url": "https://disease-ontology.org/term/DOID:0081098", "evidence": [ { "id": "0081098", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081098" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "TRAPP complex", "id": "GO:0030008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030008", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "TRAPPII protein complex", "id": "GO:1990071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990071", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "acroblast", "id": "GO:0036063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036063", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "actomyosin contractile ring contraction", "id": "GO:0000916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000916", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "meiotic spindle organization", "id": "GO:0000212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000212", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "spermatocyte division", "id": "GO:0048137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048137", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "male meiosis cytokinesis", "id": "GO:0007112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007112", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "meiosis I cytokinesis", "id": "GO:0007110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007110", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" }, { "name": "meiosis II cytokinesis", "id": "GO:0007111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007111", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VIL0-1", "start_pos": "317", "end_pos": "317", "site_lbl": "Ser317", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VIL0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VIL0" } ] } ] }, { "uniprot_canonical_ac": "Q9VIL0-1", "start_pos": "329", "end_pos": "329", "site_lbl": "Thr329", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VIL0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VIL0" } ] } ] }, { "uniprot_canonical_ac": "Q9VIL0-1", "start_pos": "672", "end_pos": "672", "site_lbl": "Ser672", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VIL0", "url": "https://www.uniprot.org/uniprotkb/Q9VIL0" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VIL0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VIL0" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VIT3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIT3", "url": "https://www.uniprot.org/uniprotkb/Q9VIT3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 381, "chemical_mass": 42464.0, "gene_names": "msb1l;CG10364;Dmel\\CG10364;Dmel_CG10364;Msb1l;msb1l;msh1l", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VIV3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 405, "chemical_mass": 44773.0, "gene_names": "Ctu2;CG10189;CTU2;Ctu2;Dmel\\CG10189;i180;i199", "protein_name": "Cytoplasmic tRNA 2-thiolation protein 2", "disease": [], "biological_process": [ { "name": "tRNA wobble position uridine thiolation", "id": "GO:0002143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002143", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" }, { "name": "tRNA thio-modification", "id": "GO:0034227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034227", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" }, { "name": "protein urmylation", "id": "GO:0032447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032447", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" } ], "molecular_function": [ { "name": "sulfurtransferase activity", "id": "GO:0016783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016783", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" }, { "name": "cytosolic tRNA wobble base thiouridylase complex", "id": "GO:0002144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002144", "evidence": [ { "database": "UniProtKB", "id": "Q9VIV3", "url": "https://www.uniprot.org/uniprotkb/Q9VIV3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJ34-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJ34", "url": "https://www.uniprot.org/uniprotkb/Q9VJ34" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 585, "chemical_mass": 66005.0, "gene_names": "CG10428;Dmel\\CG10428", "protein_name": "Glutathione S-transferase C-terminal domain-containing protein homolog", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ34", "url": "https://www.uniprot.org/uniprotkb/Q9VJ34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJ71-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJ71", "url": "https://www.uniprot.org/uniprotkb/Q9VJ71" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 492, "chemical_mass": 57113.0, "gene_names": "Cyp310a1;310a1;CG10391;Cyp310a1;Cyp310a;Cyp310;Dmel\\CG10391;H;anon-EST:CL1d7;cyp310a1", "protein_name": "Probable cytochrome P450 310a1", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ71", "url": "https://www.uniprot.org/uniprotkb/Q9VJ71" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ71", "url": "https://www.uniprot.org/uniprotkb/Q9VJ71" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ71", "url": "https://www.uniprot.org/uniprotkb/Q9VJ71" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ71", "url": "https://www.uniprot.org/uniprotkb/Q9VJ71" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ71", "url": "https://www.uniprot.org/uniprotkb/Q9VJ71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJ83-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 241, "chemical_mass": 26267.0, "gene_names": "grnd;CG10176;Dmel\\CG10176;Grnd;grnd", "protein_name": "Tumor necrosis factor receptor superfamily member grnd", "disease": [], "biological_process": [ { "name": "negative regulation of reactive oxygen species biosynthetic process", "id": "GO:1903427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903427", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" }, { "name": "positive regulation of programmed cell death", "id": "GO:0043068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043068", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" }, { "name": "positive regulation of neuron remodeling", "id": "GO:1904801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904801", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" } ], "molecular_function": [ { "name": "tumor necrosis factor receptor activity", "id": "GO:0005031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005031", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VJ83-1", "start_pos": "63", "end_pos": "63", "site_lbl": "Asn63", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 63, "start_aa": "Asn", "end_pos": 63, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn63", "evidence": [ { "id": "Q9VJ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Loss of glycosylation. Increases ligand affinity for the TNF egr.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" }, { "database": "PubMed", "id": "29870719", "url": "https://glygen.org/publication/PubMed/29870719" }, { "database": "PubMed", "id": "38944657", "url": "https://glygen.org/publication/PubMed/38944657" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ83-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Phe46", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Abrogates binding to egr, probably due to disruption of the hydrophobic core. Abrogates egr-induced apoptosis in wing imaginal discs.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" }, { "database": "PubMed", "id": "33824334", "url": "https://glygen.org/publication/PubMed/33824334" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ83-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Thr51", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Abrogates binding to egr.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" }, { "database": "PubMed", "id": "33824334", "url": "https://glygen.org/publication/PubMed/33824334" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ83-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Glu52", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Partially impairs association with egr.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" }, { "database": "PubMed", "id": "33824334", "url": "https://glygen.org/publication/PubMed/33824334" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ83-1", "start_pos": "66", "end_pos": "66", "site_lbl": "His66", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Partially impairs association with egr. Partially impairs egr-induced apoptosis in wing imaginal discs.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" }, { "database": "PubMed", "id": "33824334", "url": "https://glygen.org/publication/PubMed/33824334" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ83-1", "start_pos": "67", "end_pos": "67", "site_lbl": "Asn67", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Partially impairs association with egr.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ83", "url": "https://www.uniprot.org/uniprotkb/Q9VJ83" }, { "database": "PubMed", "id": "33824334", "url": "https://glygen.org/publication/PubMed/33824334" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJ87-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1330, "chemical_mass": 151637.0, "gene_names": "ncm;CG12750;Dmel\\CG12750;E-2a;NCM;Ncm;l(2)SH0931;l(2)SH2 0931;ncm", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "1108", "end_pos": "1108", "site_lbl": "Thr1108", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "1111", "end_pos": "1111", "site_lbl": "Ser1111", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "1121", "end_pos": "1121", "site_lbl": "Ser1121", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "1180", "end_pos": "1180", "site_lbl": "Ser1180", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "1181", "end_pos": "1181", "site_lbl": "Ser1181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "1182", "end_pos": "1182", "site_lbl": "Tyr1182", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Thr201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] }, { "uniprot_canonical_ac": "Q9VJ87-1", "start_pos": "221", "end_pos": "221", "site_lbl": "Ser221", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ87", "url": "https://www.uniprot.org/uniprotkb/Q9VJ87" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VJ87", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VJ87" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJB6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1799, "chemical_mass": 200480.0, "gene_names": "CadN2;CG42829;CG7527;CT23007;CadN2;DN-Cad2;DN-cad2;DN-like;DNcad2;DmNCad2;Dmel\\CG42829;N-Cad2;NCad2;Ncad2;cadN2", "protein_name": "Putative neural-cadherin 2", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "axon extension involved in axon guidance", "id": "GO:0048846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048846", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "ommatidial rotation", "id": "GO:0016318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016318", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "R7 cell development", "id": "GO:0045467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045467", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "R8 cell development", "id": "GO:0045463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045463", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "Q9VJB6", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Asn118", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 118, "start_aa": "Asn", "end_pos": 118, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "1376", "end_pos": "1376", "site_lbl": "Asn1376", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1376, "start_aa": "Asn", "end_pos": 1376, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1376", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "13", "end_pos": "13", "site_lbl": "Asn13", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 13, "start_aa": "Asn", "end_pos": 13, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn13", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "1437", "end_pos": "1437", "site_lbl": "Asn1437", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1437, "start_aa": "Asn", "end_pos": 1437, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1437", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "195", "end_pos": "195", "site_lbl": "Asn195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 195, "start_aa": "Asn", "end_pos": 195, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn195", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Asn260", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 260, "start_aa": "Asn", "end_pos": 260, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn260", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Asn264", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 264, "start_aa": "Asn", "end_pos": 264, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn264", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "283", "end_pos": "283", "site_lbl": "Asn283", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 283, "start_aa": "Asn", "end_pos": 283, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn283", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Asn377", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 377, "start_aa": "Asn", "end_pos": 377, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn377", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "601", "end_pos": "601", "site_lbl": "Asn601", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 601, "start_aa": "Asn", "end_pos": 601, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn601", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Asn64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 64, "start_aa": "Asn", "end_pos": 64, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn64", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "793", "end_pos": "793", "site_lbl": "Asn793", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 793, "start_aa": "Asn", "end_pos": 793, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn793", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Asn86", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 86, "start_aa": "Asn", "end_pos": 86, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn86", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "910", "end_pos": "910", "site_lbl": "Asn910", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 910, "start_aa": "Asn", "end_pos": 910, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn910", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "948", "end_pos": "948", "site_lbl": "Asn948", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 948, "start_aa": "Asn", "end_pos": 948, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn948", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VJB6-1", "start_pos": "969", "end_pos": "969", "site_lbl": "Asn969", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 969, "start_aa": "Asn", "end_pos": 969, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn969", "evidence": [ { "id": "Q9VJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJB6#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJC7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJC7", "url": "https://www.uniprot.org/uniprotkb/Q9VJC7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 318, "chemical_mass": 35412.0, "gene_names": "mEFTs;CG6412;Dmel\\CG6412;mEFTs;mtEF-Ts", "protein_name": "Elongation factor Ts, mitochondrial", "disease": [ { "disease_id": "DOID:0111486", "name": "combined oxidative phosphorylation deficiency 3", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the TSFM gene on chromosome 12q14.1.", "url": "https://disease-ontology.org/term/DOID:0111486", "evidence": [ { "id": "0111486", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111486" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC7", "url": "https://www.uniprot.org/uniprotkb/Q9VJC7" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC7", "url": "https://www.uniprot.org/uniprotkb/Q9VJC7" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC7", "url": "https://www.uniprot.org/uniprotkb/Q9VJC7" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC7", "url": "https://www.uniprot.org/uniprotkb/Q9VJC7" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translational elongation", "id": "GO:0070125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070125", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC7", "url": "https://www.uniprot.org/uniprotkb/Q9VJC7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJK8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJK8", "url": "https://www.uniprot.org/uniprotkb/Q9VJK8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 297, "chemical_mass": 34065.0, "gene_names": "jhamt;BG:DS09218.5;CG17330;DmJHAMT;Dmel\\CG17330;JAHMT;JHAMT;JHamt;Jhamt;jhamt", "protein_name": "Juvenile hormone acid O-methyltransferase", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9VJK8", "url": "https://www.uniprot.org/uniprotkb/Q9VJK8" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q9VJK8", "url": "https://www.uniprot.org/uniprotkb/Q9VJK8" } ], "pmid": "" }, { "name": "juvenile hormone biosynthetic process", "id": "GO:0006718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006718", "evidence": [ { "database": "UniProtKB", "id": "Q9VJK8", "url": "https://www.uniprot.org/uniprotkb/Q9VJK8" } ], "pmid": "" } ], "molecular_function": [ { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "Q9VJK8", "url": "https://www.uniprot.org/uniprotkb/Q9VJK8" } ], "pmid": "" }, { "name": "farnesoic acid O-methyltransferase activity", "id": "GO:0019010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019010", "evidence": [ { "database": "UniProtKB", "id": "Q9VJK8", "url": "https://www.uniprot.org/uniprotkb/Q9VJK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJV8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 361, "chemical_mass": 41027.0, "gene_names": "PolG2;BG:DS00941.9;CG33084;CG33650;CG8969;D-pol gamma-beta;DNA pol-gam.35;DNApol-gamma.35;DNApol-gamma35;DNApol-gamma;DNApolG2;DNApolg-35;Dmel\\CG33650;MtPolB;POLG;Pol gamma;PolG2;PolG;Polgamma-35;Polgamma-beta;Polgamma;Polg;br16;l(2)34De;l(2)br16;pol gamma-alpha;pol gamma-beta;pol gamma35;polgamma-beta;polgamma", "protein_name": "DNA polymerase subunit gamma-2, mitochondrial", "disease": [ { "disease_id": "DOID:0070446", "name": "mitochondrial DNA depletion syndrome 16", "description": "A mitochondrial DNA depletion syndrome characterized by infantile onset of fulminant hepatic liver failure that has_material_basis_in homozygous mutation in the POLG2 gene on chromosome 17q23.3.", "url": "https://disease-ontology.org/term/DOID:0070446", "evidence": [ { "id": "0070446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070446" } ], "weight": 0.0 }, { "disease_id": "DOID:0070447", "name": "mitochondrial DNA depletion syndrome 16B", "description": "A mitochondrial DNA depletion syndrome characterized by childhood onset of progressive neuroophthalmic manifestation including optic atrophy, mixed polyneuropathy, spinal and cerebellar ataxia and generalized chorea that has_material_basis_in homozygous mutation in the POLG2 gene on chromosome 17q23.", "url": "https://disease-ontology.org/term/DOID:0070447", "evidence": [ { "id": "0070447", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070447" } ], "weight": 0.0 }, { "disease_id": "DOID:0111525", "name": "autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4", "description": "A chronic progressive external ophthalmoplegia that has_material_basis_in heterozygous mutation in the POLG2 gene on chromosome 17q23.3.", "url": "https://disease-ontology.org/term/DOID:0111525", "evidence": [ { "id": "0111525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111525" } ], "weight": 0.0 }, { "disease_id": "DOID:12679", "name": "nephrocalcinosis", "description": "", "url": "https://disease-ontology.org/term/DOID:12679", "evidence": [ { "id": "12679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12679" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA polymerase processivity factor activity", "id": "GO:0030337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030337", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" }, { "name": "DNA/RNA hybrid binding", "id": "GO:0071667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071667", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" }, { "name": "gamma DNA polymerase complex", "id": "GO:0005760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005760", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial DNA replication", "id": "GO:0006264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006264", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VJV8-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Gly31", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Loss of mitochondrial DNA which disrupts mitochondrial morphology; larval brains are smaller due to defective cell proliferation leading to death at the pupal stage.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJV8", "url": "https://www.uniprot.org/uniprotkb/Q9VJV8" }, { "database": "PubMed", "id": "11917141", "url": "https://glygen.org/publication/PubMed/11917141" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 465, "chemical_mass": 50085.0, "gene_names": "loqs;CG6866;Dmel\\CG6866;Dmel_CG6866;LOQS;Loqs-PD;Loqs;LqPD;R3D1-L;R3D1-S;R3D1;TRBP;cg6866;dRax;loqs;loq;r3d1", "protein_name": "Protein Loquacious", "disease": [ { "disease_id": "DOID:0090048", "name": "dystonia 16", "description": "A multifocal dystonia that is characterized by early-onset progressive limb dystonia, laryngeal and oromandibular dystonia, and parkinsonism, and that has_material_basis_in autosomal recessive inheritance of homozygous mutation in the protein activator of interferon induced protein kinase EIF2AK2 (PRKRA) gene on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0090048", "evidence": [ { "id": "0090048", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090048" } ], "weight": 0.0 } ], "biological_process": [ { "name": "RISC complex assembly", "id": "GO:0070922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070922", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "miRNA metabolic process", "id": "GO:0010586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010586", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "pre-miRNA processing", "id": "GO:0031054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031054", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "siRNA processing", "id": "GO:0030422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030422", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "female germ-line stem cell asymmetric division", "id": "GO:0048132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048132", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "germ-line stem cell population maintenance", "id": "GO:0030718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030718", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "dosage compensation by hyperactivation of X chromosome", "id": "GO:0009047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009047", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "regulation of regulatory ncRNA processing", "id": "GO:0070920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070920", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" } ], "molecular_function": [ { "name": "RISC complex binding", "id": "GO:1905172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905172", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "siRNA binding", "id": "GO:0035197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035197", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" }, { "name": "RISC-loading complex", "id": "GO:0070578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070578", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VJY9-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Thr150", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 150, "start_aa": "Thr", "end_pos": 150, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr150", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VJY9-1", "start_pos": "443", "end_pos": "443", "site_lbl": "Thr443", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 443, "start_aa": "Thr", "end_pos": 443, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr443", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VJY9-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Glu347", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Reduced interaction with Dcr-2.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" }, { "database": "PubMed", "id": "35768513", "url": "https://glygen.org/publication/PubMed/35768513" } ] } ] }, { "uniprot_canonical_ac": "Q9VJY9-1", "start_pos": "356", "end_pos": "356", "site_lbl": "Leu356", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Reduced interaction with Dcr-2.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" }, { "database": "PubMed", "id": "35768513", "url": "https://glygen.org/publication/PubMed/35768513" } ] } ] }, { "uniprot_canonical_ac": "Q9VJY9-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Gln359", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "D", "comment": "Reduced interaction with Dcr-2.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" }, { "database": "PubMed", "id": "35768513", "url": "https://glygen.org/publication/PubMed/35768513" } ] } ] }, { "uniprot_canonical_ac": "Q9VJY9-1", "start_pos": "419", "end_pos": "419", "site_lbl": "Phe419", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Strong reduction in Dcr-1 activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" }, { "database": "PubMed", "id": "26769856", "url": "https://glygen.org/publication/PubMed/26769856" } ] } ] }, { "uniprot_canonical_ac": "Q9VJY9-1", "start_pos": "426", "end_pos": "426", "site_lbl": "Leu426", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "R", "comment": "Decreased binding to Dcr-1.", "evidence": [ { "database": "UniProtKB", "id": "Q9VJY9", "url": "https://www.uniprot.org/uniprotkb/Q9VJY9" }, { "database": "PubMed", "id": "26769856", "url": "https://glygen.org/publication/PubMed/26769856" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VJZ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VJZ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 216, "chemical_mass": 23631.0, "gene_names": "Grx3;CG6523;Dmel\\CG6523;Dmel_CG6523;Grx3;Grx4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VJZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VJZ6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VJZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VJZ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VJZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VJZ6" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "Q9VJZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VJZ6" } ], "pmid": "" }, { "name": "protein-glutathione oxidoreductase (glutathione) activity", "id": "GO:0141049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141049", "evidence": [ { "database": "UniProtKB", "id": "Q9VJZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VJZ6" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "Q9VJZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VJZ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VK50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1123, "chemical_mass": 128918.0, "gene_names": "ACXE;ACXE;AC;CG17178;DACXE;Dmel\\CG17178", "protein_name": "Adenylyl cyclase X E", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "pmid": "" } ], "biological_process": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q9VK50", "url": "https://www.uniprot.org/uniprotkb/Q9VK50" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VK91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VK91", "url": "https://www.uniprot.org/uniprotkb/Q9VK91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 395, "chemical_mass": 45179.0, "gene_names": "Fam92;CG6405;Dmel\\CG6405;FAM92;Fam92;fam92", "protein_name": "CBY1-interacting BAR domain-containing protein homolog", "disease": [ { "disease_id": "DOID:1148", "name": "polydactyly", "description": "A physical disorder that is characterized by the presence of more than five fingers per hand or five toes per foot.", "url": "https://disease-ontology.org/term/DOID:1148", "evidence": [ { "id": "1148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1148" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "Q9VK91", "url": "https://www.uniprot.org/uniprotkb/Q9VK91" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VK91", "url": "https://www.uniprot.org/uniprotkb/Q9VK91" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VK91", "url": "https://www.uniprot.org/uniprotkb/Q9VK91" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VK91", "url": "https://www.uniprot.org/uniprotkb/Q9VK91" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VK91", "url": "https://www.uniprot.org/uniprotkb/Q9VK91" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VK91", "url": "https://www.uniprot.org/uniprotkb/Q9VK91" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "Q9VK91", "url": "https://www.uniprot.org/uniprotkb/Q9VK91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VKA5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 475, "chemical_mass": 54585.0, "gene_names": "Gr33a;CG17213;Dmel\\CG17213;GR33a;Gr33C1;Gr33a", "protein_name": "Gustatory and pheromone receptor 33a", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "male mating behavior", "id": "GO:0060179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060179", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of bitter taste", "id": "GO:0001580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001580", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "sensory perception of bitter taste", "id": "GO:0050913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050913", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" }, { "name": "ionotropic taste receptor activity", "id": "GO:0170021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170021", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA5", "url": "https://www.uniprot.org/uniprotkb/Q9VKA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VKH0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKH0", "url": "https://www.uniprot.org/uniprotkb/Q9VKH0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 570, "chemical_mass": 64910.0, "gene_names": "Cog8;CG6488;COG8;Cog8;Dmel\\CG6488", "protein_name": "Conserved oligomeric Golgi complex subunit 8", "disease": [ { "disease_id": "DOID:0070260", "name": "congenital disorder of glycosylation type IIh", "description": "A congenital disorder of glycosylation type II that has_material_basis_in a mutation of the COG8 gene on chromosome 16q22.1.", "url": "https://disease-ontology.org/term/DOID:0070260", "evidence": [ { "id": "0070260", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070260" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH0", "url": "https://www.uniprot.org/uniprotkb/Q9VKH0" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH0", "url": "https://www.uniprot.org/uniprotkb/Q9VKH0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH0", "url": "https://www.uniprot.org/uniprotkb/Q9VKH0" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH0", "url": "https://www.uniprot.org/uniprotkb/Q9VKH0" } ], "pmid": "" }, { "name": "retrograde transport, vesicle recycling within Golgi", "id": "GO:0000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000301", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH0", "url": "https://www.uniprot.org/uniprotkb/Q9VKH0" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH0", "url": "https://www.uniprot.org/uniprotkb/Q9VKH0" } ], "pmid": "" }, { "name": "spermatid nucleus elongation", "id": "GO:0007290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007290", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH0", "url": "https://www.uniprot.org/uniprotkb/Q9VKH0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VKV5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 319, "chemical_mass": 36838.0, "gene_names": "holn1;CG5198;Dmel\\CG5198;holn1", "protein_name": "CD2 antigen cytoplasmic tail-binding protein 2 homolog", "disease": [], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" } ], "pmid": "" }, { "name": "positive regulation of wound healing", "id": "GO:0090303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090303", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" } ], "pmid": "" }, { "name": "wing disc development", "id": "GO:0035220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035220", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VKV5-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Ser25", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VKV5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VKV5" } ] } ] }, { "uniprot_canonical_ac": "Q9VKV5-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Ser30", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VKV5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VKV5" } ] } ] }, { "uniprot_canonical_ac": "Q9VKV5-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Tyr37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VKV5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VKV5" } ] } ] }, { "uniprot_canonical_ac": "Q9VKV5-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Ser41", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV5", "url": "https://www.uniprot.org/uniprotkb/Q9VKV5" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VKV5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VKV5" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VKV8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 199, "chemical_mass": 23331.0, "gene_names": "Bug22;Bug22;CFAP20;CG5343;Dmel\\CG5343", "protein_name": "Cilia- and flagella-associated protein 20", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "positive regulation of cell motility", "id": "GO:2000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000147", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "locomotion", "id": "GO:0040011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040011", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "protein polyglycylation", "id": "GO:0018094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018094", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "sperm individualization", "id": "GO:0007291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007291", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency involved in ciliary motility", "id": "GO:0060296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060296", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" }, { "name": "positive regulation of flagellated sperm motility", "id": "GO:1902093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902093", "evidence": [ { "database": "UniProtKB", "id": "Q9VKV8", "url": "https://www.uniprot.org/uniprotkb/Q9VKV8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VL18-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 256, "chemical_mass": 28935.0, "gene_names": "eEF1delta;CG4912;Dmel\\CG4912;eEF1delta;eEF1d;eEf1delta", "protein_name": "Probable elongation factor 1-delta", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" } ], "pmid": "" }, { "name": "eukaryotic translation elongation factor 1 complex", "id": "GO:0005853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005853", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" } ], "pmid": "" } ], "biological_process": [ { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VL18-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VL18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VL18" } ] } ] }, { "uniprot_canonical_ac": "Q9VL18-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VL18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VL18" } ] } ] }, { "uniprot_canonical_ac": "Q9VL18-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Ser37", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VL18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VL18" } ] } ] }, { "uniprot_canonical_ac": "Q9VL18-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Ser53", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VL18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VL18" } ] } ] }, { "uniprot_canonical_ac": "Q9VL18-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Ser89", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VL18", "url": "https://www.uniprot.org/uniprotkb/Q9VL18" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VL18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VL18" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VL78-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL78", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 439, "chemical_mass": 48795.0, "gene_names": "Fkbp59;CG4535;Dmel\\CG4535;Dmel_CG4535;FKBP59-bp1;FKBP59;Fkbp59;anon-WO0118547.161;dFKBP4;dFKBP59;fkbp59;l(2)k00424;l(2)k09010", "protein_name": "FK506-binding protein 59", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:4674", "name": "androgen insensitivity syndrome", "description": "A disorder of sexual development that is characterized by the inability of the cell to respond to androgens in individuals with a karyotype of 46,XY resulting in female physical traits but male genetic makeup.", "url": "https://disease-ontology.org/term/DOID:4674", "evidence": [ { "id": "4674", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4674" } ], "weight": 0.0 }, { "disease_id": "DOID:809", "name": "cocaine abuse", "description": "A substance abuse that involves the recurring use of cocaine despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:809", "evidence": [ { "id": "809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:809" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of calcium ion transport", "id": "GO:0051924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051924", "evidence": [ { "database": "UniProtKB", "id": "Q9VL78", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VL78", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ], "pmid": "" }, { "name": "detection of light stimulus involved in visual perception", "id": "GO:0050908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050908", "evidence": [ { "database": "UniProtKB", "id": "Q9VL78", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ], "pmid": "" } ], "molecular_function": [ { "name": "FK506 binding", "id": "GO:0005528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005528", "evidence": [ { "database": "UniProtKB", "id": "Q9VL78", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "Q9VL78", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ], "pmid": "" } ], "cellular_component": [ { "name": "inaD signaling complex", "id": "GO:0016027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016027", "evidence": [ { "database": "UniProtKB", "id": "Q9VL78", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VL92-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL92", "url": "https://www.uniprot.org/uniprotkb/Q9VL92" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 526, "chemical_mass": 60883.0, "gene_names": "Cyp4e3;4e3;CG4105;CYP4E3;Cyp4E3;Cyp4e3;Dmel\\CG4105;P-450;P450;cyp4e3", "protein_name": "Cytochrome P450 4e3", "disease": [ { "disease_id": "DOID:0050664", "name": "Bietti crystalline corneoretinal dystrophy", "description": "A retinal degeneration that is characterized by crystals in the cornea, shiny deposits on the retina and progressive atrophy of the retina, choriocapillaris and choroid, has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the CYP4V2 gene on chromosome 4q35.", "url": "https://disease-ontology.org/term/DOID:0050664", "evidence": [ { "id": "0050664", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050664" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VL92", "url": "https://www.uniprot.org/uniprotkb/Q9VL92" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VL92", "url": "https://www.uniprot.org/uniprotkb/Q9VL92" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VL92", "url": "https://www.uniprot.org/uniprotkb/Q9VL92" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VL92", "url": "https://www.uniprot.org/uniprotkb/Q9VL92" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VL92", "url": "https://www.uniprot.org/uniprotkb/Q9VL92" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VL92", "url": "https://www.uniprot.org/uniprotkb/Q9VL92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VL92-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VL93-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL93", "url": "https://www.uniprot.org/uniprotkb/Q9VL93" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 110, "chemical_mass": 12064.0, "gene_names": "Dmel\\CG13117;BcDNA:SD27505;CG13117;Dmel\\CG13117;Dmel_CG13117", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VLD6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 315, "chemical_mass": 34681.0, "gene_names": "borr;BORR;Borr;Bor;CG4454;Dmel\\CG4454;borr;dBor", "protein_name": "Borealin", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "chromosome passenger complex", "id": "GO:0032133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032133", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "meiotic spindle midzone", "id": "GO:1990385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990385", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "mitotic spindle midzone assembly", "id": "GO:0051256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051256", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" }, { "name": "protein localization to spindle microtubule", "id": "GO:1902889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902889", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VLD6-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Thr146", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VLD6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VLD6" } ] } ] }, { "uniprot_canonical_ac": "Q9VLD6-1", "start_pos": "152", "end_pos": "152", "site_lbl": "Ser152", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VLD6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VLD6" } ] } ] }, { "uniprot_canonical_ac": "Q9VLD6-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Ser163", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VLD6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VLD6" } ] } ] }, { "uniprot_canonical_ac": "Q9VLD6-1", "start_pos": "205", "end_pos": "205", "site_lbl": "Ser205", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VLD6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VLD6" } ] } ] }, { "uniprot_canonical_ac": "Q9VLD6-1", "start_pos": "209", "end_pos": "209", "site_lbl": "Thr209", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VLD6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VLD6" } ] } ] }, { "uniprot_canonical_ac": "Q9VLD6-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Ser218", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VLD6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VLD6" } ] } ] }, { "uniprot_canonical_ac": "Q9VLD6-1", "start_pos": "220", "end_pos": "220", "site_lbl": "Ser220", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VLD6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VLD6" } ] } ] }, { "uniprot_canonical_ac": "Q9VLD6-1", "start_pos": "244", "end_pos": "244", "site_lbl": "Ser244", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VLD6", "url": "https://www.uniprot.org/uniprotkb/Q9VLD6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VLD6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VLD6" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VLL0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLL0", "url": "https://www.uniprot.org/uniprotkb/Q9VLL0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1012, "chemical_mass": 113084.0, "gene_names": "Aasdh;Aasdh;CG13401;Dmel\\CG13401;Dmel_CG13401;U26", "protein_name": "Beta-alanine-activating enzyme", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VLL0", "url": "https://www.uniprot.org/uniprotkb/Q9VLL0" } ], "pmid": "" }, { "name": "acid-thiol ligase activity", "id": "GO:0016878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016878", "evidence": [ { "database": "UniProtKB", "id": "Q9VLL0", "url": "https://www.uniprot.org/uniprotkb/Q9VLL0" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "Q9VLL0", "url": "https://www.uniprot.org/uniprotkb/Q9VLL0" } ], "pmid": "" }, { "name": "beta-alanine metabolic process", "id": "GO:0019482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019482", "evidence": [ { "database": "UniProtKB", "id": "Q9VLL0", "url": "https://www.uniprot.org/uniprotkb/Q9VLL0" } ], "pmid": "" }, { "name": "amino acid activation for nonribosomal peptide biosynthetic process", "id": "GO:0043041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043041", "evidence": [ { "database": "UniProtKB", "id": "Q9VLL0", "url": "https://www.uniprot.org/uniprotkb/Q9VLL0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VLM5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 112, "chemical_mass": 12526.0, "gene_names": "Dad1;BcDNA:RE23864;CG13393;Dad1;Dmel\\CG13393;OST;dDad1;l(2)k12914", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" }, { "name": "oligosaccharyltransferase complex", "id": "GO:0008250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008250", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" }, { "name": "oligosaccharyltransferase complex A", "id": "GO:0160226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160226", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" }, { "name": "oligosaccharyltransferase complex B", "id": "GO:0160227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160227", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" }, { "name": "protein co-translational transfer of dolichol-linked oligosaccharide", "id": "GO:0180058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180058", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" }, { "name": "protein post-translational transfer of dolichol-linked oligosaccharide", "id": "GO:0180057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180057", "evidence": [ { "database": "UniProtKB", "id": "Q9VLM5", "url": "https://www.uniprot.org/uniprotkb/Q9VLM5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VLS9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLS9", "url": "https://www.uniprot.org/uniprotkb/Q9VLS9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 292, "chemical_mass": 32733.0, "gene_names": "CG12375;Dmel\\CG12375", "protein_name": "Beta-lactamase-like protein 2 homolog", "disease": [], "cellular_component": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VLS9", "url": "https://www.uniprot.org/uniprotkb/Q9VLS9" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VLS9", "url": "https://www.uniprot.org/uniprotkb/Q9VLS9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VLS9", "url": "https://www.uniprot.org/uniprotkb/Q9VLS9" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "Q9VLS9", "url": "https://www.uniprot.org/uniprotkb/Q9VLS9" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9VLS9", "url": "https://www.uniprot.org/uniprotkb/Q9VLS9" } ], "pmid": "" } ], "biological_process": [ { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "Q9VLS9", "url": "https://www.uniprot.org/uniprotkb/Q9VLS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VM08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 470, "chemical_mass": 53598.0, "gene_names": "Gr28b;28A3;CG13788;Dmel\\CG13788;GR28B(D);GR28B;GR28b;GRLU.2;Gr28A3;Gr28A4;Gr28b(D);Gr28b.a;Gr28b.b;Gr28b.c;Gr28b.d;Gr28b.e;Gr28bA;Gr28bB;Gr28bC;Gr28bD;Gr28bE;Gr28be;Gr28b;GrLU2;LU.2;gr28b", "protein_name": "Putative gustatory receptor 28b", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "feeding behavior", "id": "GO:0007631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007631", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "thermosensory behavior", "id": "GO:0040040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040040", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "negative phototaxis", "id": "GO:0046957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046957", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "melanization defense response", "id": "GO:0035006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035006", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9VM08", "url": "https://www.uniprot.org/uniprotkb/Q9VM08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VM08-1", "start_pos": "454", "end_pos": "454", "site_lbl": "Asn454", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 454, "start_aa": "Asn", "end_pos": 454, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn454", "evidence": [ { "id": "Q9VM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM08#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VM08-1", "start_pos": "464", "end_pos": "464", "site_lbl": "Asn464", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 464, "start_aa": "Asn", "end_pos": 464, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn464", "evidence": [ { "id": "Q9VM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM08#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VM08-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Asn467", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 467, "start_aa": "Asn", "end_pos": 467, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn467", "evidence": [ { "id": "Q9VM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM08#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VM09-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 450, "chemical_mass": 51857.0, "gene_names": "Gr28a;28A.1;CG13787;Dmel\\CG13787;GR28A.1;GR28a;Gr28A1;Gr28A2;Gr28a", "protein_name": "Putative gustatory receptor 28a", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9VM09", "url": "https://www.uniprot.org/uniprotkb/Q9VM09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VM09-1", "start_pos": "438", "end_pos": "438", "site_lbl": "Asn438", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 438, "start_aa": "Asn", "end_pos": 438, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn438", "evidence": [ { "id": "Q9VM09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM09#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VM09-1", "start_pos": "82", "end_pos": "82", "site_lbl": "Asn82", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 82, "start_aa": "Asn", "end_pos": 82, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn82", "evidence": [ { "id": "Q9VM09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM09#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VM33-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM33", "url": "https://www.uniprot.org/uniprotkb/Q9VM33" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 745, "chemical_mass": 83509.0, "gene_names": "mEFG1;B;CG4567;Dmel\\CG4567;GFM1;G;dEF-G1;ico;l(2)27Cb;l(2)27Ea;mEFG1", "protein_name": "Elongation factor G, mitochondrial", "disease": [ { "disease_id": "DOID:0111474", "name": "combined oxidative phosphorylation deficiency 1", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the GFM1 gene on chromosome 3q25.32.", "url": "https://disease-ontology.org/term/DOID:0111474", "evidence": [ { "id": "0111474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111474" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q9VM33", "url": "https://www.uniprot.org/uniprotkb/Q9VM33" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VM33", "url": "https://www.uniprot.org/uniprotkb/Q9VM33" } ], "pmid": "" }, { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "Q9VM33", "url": "https://www.uniprot.org/uniprotkb/Q9VM33" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VM33", "url": "https://www.uniprot.org/uniprotkb/Q9VM33" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VM33", "url": "https://www.uniprot.org/uniprotkb/Q9VM33" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VM33", "url": "https://www.uniprot.org/uniprotkb/Q9VM33" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial translational elongation", "id": "GO:0070125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070125", "evidence": [ { "database": "UniProtKB", "id": "Q9VM33", "url": "https://www.uniprot.org/uniprotkb/Q9VM33" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VM95-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM95", "url": "https://www.uniprot.org/uniprotkb/Q9VM95" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 488, "chemical_mass": 55953.0, "gene_names": "Aatf;AATF;Aatf;CG11188;Che-1;Dmel\\CG11188;anon-WO0118547.190;nutmeg", "protein_name": "Protein Aatf", "disease": [ { "disease_id": "DOID:0060404", "name": "chromosome 17q12 deletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in a chromosome 17q12 deletion and that is characterized by renal cystic disease, maturity onset diabetes of the young type 5, cognitive impairment, developmental delay (particularly of speech), autistic traits and autism spectrum disorder.", "url": "https://disease-ontology.org/term/DOID:0060404", "evidence": [ { "id": "0060404", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060404" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VM95", "url": "https://www.uniprot.org/uniprotkb/Q9VM95" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VM95", "url": "https://www.uniprot.org/uniprotkb/Q9VM95" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of programmed cell death", "id": "GO:0043069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043069", "evidence": [ { "database": "UniProtKB", "id": "Q9VM95", "url": "https://www.uniprot.org/uniprotkb/Q9VM95" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VM95", "url": "https://www.uniprot.org/uniprotkb/Q9VM95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VM95-1", "start_pos": "26", "end_pos": "26", "site_lbl": "Ser26", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VM95", "url": "https://www.uniprot.org/uniprotkb/Q9VM95" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VM95", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VM95" } ] } ] }, { "uniprot_canonical_ac": "Q9VM95-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Ser28", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VM95", "url": "https://www.uniprot.org/uniprotkb/Q9VM95" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VM95", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VM95" } ] } ] }, { "uniprot_canonical_ac": "Q9VM95-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VM95", "url": "https://www.uniprot.org/uniprotkb/Q9VM95" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VM95", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VM95" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMC9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMC9", "url": "https://www.uniprot.org/uniprotkb/Q9VMC9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 300, "chemical_mass": 34911.0, "gene_names": "KFase;CG9542;Dmel\\CG9542;Dmel_CG9542;KFase;Kf2", "protein_name": "Kynurenine formamidase", "disease": [], "molecular_function": [ { "name": "arylformamidase activity", "id": "GO:0004061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004061", "evidence": [ { "database": "UniProtKB", "id": "Q9VMC9", "url": "https://www.uniprot.org/uniprotkb/Q9VMC9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VMC9", "url": "https://www.uniprot.org/uniprotkb/Q9VMC9" } ], "pmid": "" } ], "biological_process": [ { "name": "L-tryptophan catabolic process to kynurenine", "id": "GO:0019441", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019441", "evidence": [ { "database": "UniProtKB", "id": "Q9VMC9", "url": "https://www.uniprot.org/uniprotkb/Q9VMC9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1659, "chemical_mass": 183875.0, "gene_names": "Daxx;CG9537;DAXX;DLP;Daxx;Dmel\\CG9537;dlp", "protein_name": "Daxx-like protein", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0080521", "name": "lung non-squamous non-small cell carcinoma", "description": "A lung non-small cell carcinoma that is characterized by the lack of evidence of squamous differentiation.", "url": "https://disease-ontology.org/term/DOID:0080521", "evidence": [ { "id": "0080521", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080521" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:11240", "name": "appendiceal neoplasm", "description": "", "url": "https://disease-ontology.org/term/DOID:11240", "evidence": [ { "id": "11240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11240" } ], "weight": 0.0 }, { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 }, { "disease_id": "DOID:169", "name": "neuroendocrine tumor", "description": "An endocrine gland cancer that has_material_basis_in neuroendocrine cells.", "url": "https://disease-ontology.org/term/DOID:169", "evidence": [ { "id": "169", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:169" } ], "weight": 0.0 }, { "disease_id": "DOID:1798", "name": "pancreatic endocrine carcinoma", "description": "An islet cell tumor that has_material_basis_in epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1798", "evidence": [ { "id": "1798", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1798" } ], "weight": 0.0 }, { "disease_id": "DOID:1799", "name": "islet cell tumor", "description": "A pancreatic cancer that is located_in the pancreatic islet cells.", "url": "https://disease-ontology.org/term/DOID:1799", "evidence": [ { "id": "1799", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1799" } ], "weight": 0.0 }, { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:4468", "name": "clear cell adenocarcinoma", "description": "An adenocarcinoma that derives_from epithelial cells which have clear cytoplasm.", "url": "https://disease-ontology.org/term/DOID:4468", "evidence": [ { "id": "4468", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4468" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD0", "url": "https://www.uniprot.org/uniprotkb/Q9VMD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VMD0-1", "start_pos": "863", "end_pos": "863", "site_lbl": "Thr863", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 863, "start_aa": "Thr", "end_pos": 863, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr863", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VMD0-1", "start_pos": "900", "end_pos": "900", "site_lbl": "Thr900", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 900, "start_aa": "Thr", "end_pos": 900, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr900", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMG0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 216, "chemical_mass": 24360.0, "gene_names": "AANATL2;AANAT2;AANATL2;CG9486;DmAANATL2;Dmel\\CG9486;aaNAT2", "protein_name": "Arylalkylamine N-acetyltransferase-like 2", "disease": [], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" } ], "pmid": "" }, { "name": "melatonin biosynthetic process", "id": "GO:0030187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030187", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" } ], "pmid": "" } ], "molecular_function": [ { "name": "aralkylamine N-acetyltransferase activity", "id": "GO:0004059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004059", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" } ], "pmid": "" }, { "name": "N-acyltransferase activity", "id": "GO:0016410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016410", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" } ], "pmid": "" }, { "name": "N-acetyltransferase activity", "id": "GO:0008080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008080", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VMG0-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Thr97", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 97, "start_aa": "Thr", "end_pos": 97, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr97", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VMG0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VMG0" } ] } ] }, { "uniprot_canonical_ac": "Q9VMG0-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Arg138", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" }, { "database": "PubMed", "id": "26476413", "url": "https://glygen.org/publication/PubMed/26476413" } ] } ] }, { "uniprot_canonical_ac": "Q9VMG0-1", "start_pos": "167", "end_pos": "167", "site_lbl": "Ser167", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" }, { "database": "PubMed", "id": "26476413", "url": "https://glygen.org/publication/PubMed/26476413" } ] } ] }, { "uniprot_canonical_ac": "Q9VMG0-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Ser171", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" }, { "database": "PubMed", "id": "26476413", "url": "https://glygen.org/publication/PubMed/26476413" } ] } ] }, { "uniprot_canonical_ac": "Q9VMG0-1", "start_pos": "206", "end_pos": "206", "site_lbl": "His206", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Loss of catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" }, { "database": "PubMed", "id": "26476413", "url": "https://glygen.org/publication/PubMed/26476413" } ] } ] }, { "uniprot_canonical_ac": "Q9VMG0-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Glu29", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Reduces catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" }, { "database": "PubMed", "id": "26476413", "url": "https://glygen.org/publication/PubMed/26476413" } ] } ] }, { "uniprot_canonical_ac": "Q9VMG0-1", "start_pos": "30", "end_pos": "30", "site_lbl": "Pro30", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Reduces catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG0", "url": "https://www.uniprot.org/uniprotkb/Q9VMG0" }, { "database": "PubMed", "id": "26476413", "url": "https://glygen.org/publication/PubMed/26476413" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMH7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMH7", "url": "https://www.uniprot.org/uniprotkb/Q9VMH7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 223, "chemical_mass": 26043.0, "gene_names": "CG9154;Dmel\\CG9154", "protein_name": "Protein-lysine N-methyltransferase CG9154", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH7", "url": "https://www.uniprot.org/uniprotkb/Q9VMH7" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH7", "url": "https://www.uniprot.org/uniprotkb/Q9VMH7" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH7", "url": "https://www.uniprot.org/uniprotkb/Q9VMH7" } ], "pmid": "" } ], "biological_process": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH7", "url": "https://www.uniprot.org/uniprotkb/Q9VMH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VML1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 691, "chemical_mass": 74053.0, "gene_names": "dsf;CG9019;DSF;Dmel\\CG9019;Dsf;NR2E4;dsf", "protein_name": "Protein dissatisfaction", "disease": [], "biological_process": [ { "name": "sex determination", "id": "GO:0007530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007530", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "mating behavior", "id": "GO:0007617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007617", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "regulation of female receptivity", "id": "GO:0045924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045924", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "copulation", "id": "GO:0007620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007620", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "mating behavior, sex discrimination", "id": "GO:0048047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048047", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "courtship behavior", "id": "GO:0007619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007619", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "egg-laying behavior", "id": "GO:0018991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018991", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "somatic sex determination", "id": "GO:0018993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018993", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "regulation of hemocyte proliferation", "id": "GO:0035206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035206", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "nuclear steroid receptor activity", "id": "GO:0003707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003707", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VML1-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Thr431", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 431, "start_aa": "Thr", "end_pos": 431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr431", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VML1-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Thr436", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 436, "start_aa": "Thr", "end_pos": 436, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr436", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VML1-1", "start_pos": "24", "end_pos": "24", "site_lbl": "His24", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "In dsf7, greatly decreased DNA binding of fragment 1-102.", "evidence": [ { "database": "UniProtKB", "id": "Q9VML1", "url": "https://www.uniprot.org/uniprotkb/Q9VML1" }, { "database": "PubMed", "id": "11977984", "url": "https://glygen.org/publication/PubMed/11977984" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMQ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 477, "chemical_mass": 51994.0, "gene_names": "Coq6;CG7277;Coq6;Dmel\\CG7277", "protein_name": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "disease": [ { "disease_id": "DOID:0070243", "name": "primary coenzyme Q10 deficiency 6", "description": "A primary coenzyme Q10 deficiency that has_material_basis_in an autosomal recessive mutation of the COQ6 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0070243", "evidence": [ { "id": "0070243", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070243" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:3204", "name": "schwannomatosis", "description": "A RASopathy characterized by the development of schwannomas or hybrid nerve sheath tumors.", "url": "https://disease-ontology.org/term/DOID:3204", "evidence": [ { "id": "3204", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3204" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" }, { "name": "ubiquinone biosynthesis complex", "id": "GO:0110142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110142", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" }, { "name": "4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity", "id": "GO:0106364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106364", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" }, { "name": "2-methoxy-6-polyprenolphenol 4-hydroxylase activity", "id": "GO:0120538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120538", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 437, "chemical_mass": 48712.0, "gene_names": "Elp4;CG6907;Dmel\\CG6907;Elp4", "protein_name": "Elongator complex protein 4", "disease": [ { "disease_id": "DOID:12271", "name": "aniridia", "description": "An iris disease that is characterized by a complete or partial absence of the colored part of the eye.", "url": "https://disease-ontology.org/term/DOID:12271", "evidence": [ { "id": "12271", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12271" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" }, { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" }, { "name": "elongator holoenzyme complex", "id": "GO:0033588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033588", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" }, { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" }, { "name": "establishment of mitotic spindle asymmetry", "id": "GO:0061867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061867", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VMQ7-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Thr187", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 187, "start_aa": "Thr", "end_pos": 187, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr187", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VMQ7-1", "start_pos": "183", "end_pos": "183", "site_lbl": "Ser183", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VMQ7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VMQ7" } ] } ] }, { "uniprot_canonical_ac": "Q9VMQ7-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Ser242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VMQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ7" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VMQ7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VMQ7" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMS7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMS7", "url": "https://www.uniprot.org/uniprotkb/Q9VMS7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 509, "chemical_mass": 58821.0, "gene_names": "Cyp4ac3;4ac3;CG14031;CYP4AC3;Cyp4AC3;Cyp4ac3;Dmel\\CG14031", "protein_name": "Probable cytochrome P450 4ac3", "disease": [ { "disease_id": "DOID:0050664", "name": "Bietti crystalline corneoretinal dystrophy", "description": "A retinal degeneration that is characterized by crystals in the cornea, shiny deposits on the retina and progressive atrophy of the retina, choriocapillaris and choroid, has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the CYP4V2 gene on chromosome 4q35.", "url": "https://disease-ontology.org/term/DOID:0050664", "evidence": [ { "id": "0050664", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050664" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS7", "url": "https://www.uniprot.org/uniprotkb/Q9VMS7" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS7", "url": "https://www.uniprot.org/uniprotkb/Q9VMS7" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS7", "url": "https://www.uniprot.org/uniprotkb/Q9VMS7" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS7", "url": "https://www.uniprot.org/uniprotkb/Q9VMS7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS7", "url": "https://www.uniprot.org/uniprotkb/Q9VMS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMS9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMS9", "url": "https://www.uniprot.org/uniprotkb/Q9VMS9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 509, "chemical_mass": 59186.0, "gene_names": "Cyp4ac1;4ac1;CG14032;CYP4ac1;Cyp4AC1;Cyp4ac1;Dmel\\CG14032;cyp4ac1", "protein_name": "Probable cytochrome P450 4ac1", "disease": [ { "disease_id": "DOID:0050664", "name": "Bietti crystalline corneoretinal dystrophy", "description": "A retinal degeneration that is characterized by crystals in the cornea, shiny deposits on the retina and progressive atrophy of the retina, choriocapillaris and choroid, has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the CYP4V2 gene on chromosome 4q35.", "url": "https://disease-ontology.org/term/DOID:0050664", "evidence": [ { "id": "0050664", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050664" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS9", "url": "https://www.uniprot.org/uniprotkb/Q9VMS9" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS9", "url": "https://www.uniprot.org/uniprotkb/Q9VMS9" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS9", "url": "https://www.uniprot.org/uniprotkb/Q9VMS9" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS9", "url": "https://www.uniprot.org/uniprotkb/Q9VMS9" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS9", "url": "https://www.uniprot.org/uniprotkb/Q9VMS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMT4", "url": "https://www.uniprot.org/uniprotkb/Q9VMT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 509, "chemical_mass": 58477.0, "gene_names": "Dmel\\CG7742;CG7742;Dmel\\CG7742;Dmel_CG7742", "protein_name": "Rab-GAP TBC domain-containing protein", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VMT4", "url": "https://www.uniprot.org/uniprotkb/Q9VMT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VMY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 448, "chemical_mass": 48885.0, "gene_names": "DhpD;CG18143;DhpD;Dmel\\CG18143", "protein_name": "Guanine deaminase", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 } ], "biological_process": [ { "name": "guanine metabolic process", "id": "GO:0046098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046098", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "pmid": "" }, { "name": "eye pigment biosynthetic process", "id": "GO:0006726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006726", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "pmid": "" }, { "name": "guanine catabolic process", "id": "GO:0006147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006147", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "pmid": "" }, { "name": "dihydropteridine metabolic process", "id": "GO:0051067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051067", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "pmid": "" }, { "name": "guanine deaminase activity", "id": "GO:0008892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008892", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "pmid": "" }, { "name": "dihydropterin deaminase activity", "id": "GO:0004153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004153", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY9", "url": "https://www.uniprot.org/uniprotkb/Q9VMY9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VN14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1390, "chemical_mass": 158239.0, "gene_names": "Cont;CG1084;CONT;CT1481;Cont;D-Axonin;DCONT;Dmel\\CG1084;cont", "protein_name": "Contactin", "disease": [ { "disease_id": "DOID:0080101", "name": "Compton-North congenital myopathy", "description": "A congenital myopathy that has_material_basis_in homozygous mutation in the CNTN1 gene on chromosome 12q12 and that is characterized antenatally, by fetal akinesia, intrauterine growth restriction and polyhydramnios, and, following birth, by severe neonatal hypotonia, severe generalized skeletal, bulbar and respiratory muscle weakness, multiple flexion contractures, and normal creatine kinase serum levels.", "url": "https://disease-ontology.org/term/DOID:0080101", "evidence": [ { "id": "0080101", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080101" } ], "weight": 0.0 }, { "disease_id": "DOID:0111691", "name": "familial adult myoclonic epilepsy 5", "description": "A familial adult myoclonic epilepsy characterized by onset of seizures in adolescence, followed by the development of cortical myoclonic tremor that has_material_basis_in homozygous or compound heterozygous mutation in the CNTN2 gene on chromosome 1q32.1.", "url": "https://disease-ontology.org/term/DOID:0111691", "evidence": [ { "id": "0111691", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111691" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:5602", "name": "T-cell adult acute lymphocytic leukemia", "description": "An adult acute lymphocytic leukemia occurring in adults and that has_material_basis_in T cells.", "url": "https://disease-ontology.org/term/DOID:5602", "evidence": [ { "id": "5602", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5602" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "septate junction", "id": "GO:0005918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005918", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" } ], "biological_process": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "axon ensheathment", "id": "GO:0008366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008366", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "establishment of glial blood-brain barrier", "id": "GO:0060857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060857", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "nerve maturation", "id": "GO:0021682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021682", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "cell adhesion involved in heart morphogenesis", "id": "GO:0061343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061343", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" }, { "name": "septate junction assembly", "id": "GO:0019991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019991", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "Q9VN14", "url": "https://www.uniprot.org/uniprotkb/Q9VN14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "1166", "end_pos": "1166", "site_lbl": "Asn1166", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1166, "start_aa": "Asn", "end_pos": 1166, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1166", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "1171", "end_pos": "1171", "site_lbl": "Asn1171", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1171, "start_aa": "Asn", "end_pos": 1171, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1171", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "1307", "end_pos": "1307", "site_lbl": "Asn1307", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1307, "start_aa": "Asn", "end_pos": 1307, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1307", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" }, { "id": "17893096", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/17893096" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Asn369", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 369, "start_aa": "Asn", "end_pos": 369, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn369", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Thr395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "537", "end_pos": "537", "site_lbl": "Asn537", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 537, "start_aa": "Asn", "end_pos": 537, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn537", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "604", "end_pos": "604", "site_lbl": "Asn604", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 604, "start_aa": "Asn", "end_pos": 604, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn604", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "629", "end_pos": "629", "site_lbl": "Asn629", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 629, "start_aa": "Asn", "end_pos": 629, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn629", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Asn691", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 691, "start_aa": "Asn", "end_pos": 691, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn691", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "774", "end_pos": "774", "site_lbl": "Asn774", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 774, "start_aa": "Asn", "end_pos": 774, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn774", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "912", "end_pos": "912", "site_lbl": "Asn912", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 912, "start_aa": "Asn", "end_pos": 912, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn912", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" }, { "id": "17893096", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/17893096" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "986", "end_pos": "986", "site_lbl": "Asn986", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 986, "start_aa": "Asn", "end_pos": 986, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn986", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN14-1", "start_pos": "991", "end_pos": "991", "site_lbl": "Asn991", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 991, "start_aa": "Asn", "end_pos": 991, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn991", "evidence": [ { "id": "Q9VN14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN14#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VN50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 280, "chemical_mass": 31105.0, "gene_names": "eIF3f1;CG9769;Dmel\\CG9769;Q9VN50;eIF3-S5-1;eIF3-S5;eIF3f1;eIF3f;eif3f", "protein_name": "Eukaryotic translation initiation factor 3 subunit F-1", "disease": [ { "disease_id": "DOID:0081228", "name": "autosomal recessive intellectual developmental disorder 67", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation or compound heterozygous mutation in the EIF3F gene on chromosome 11p15.", "url": "https://disease-ontology.org/term/DOID:0081228", "evidence": [ { "id": "0081228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081228" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "positive regulation of peptidoglycan recognition protein signaling pathway", "id": "GO:0061059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061059", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "antibacterial innate immune response", "id": "GO:0140367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140367", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "metal-dependent deubiquitinase activity", "id": "GO:0140492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140492", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex, eIF3m", "id": "GO:0071541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071541", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q9VN50", "url": "https://www.uniprot.org/uniprotkb/Q9VN50" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VN93-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN93", "url": "https://www.uniprot.org/uniprotkb/Q9VN93" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 614, "chemical_mass": 68961.0, "gene_names": "CtsF;CG12163;CTSF;Cts8;Cts9;CtsF;Dmel\\CG12163;anon-WO0118547.305", "protein_name": "Cathepsin F", "disease": [ { "disease_id": "DOID:0110727", "name": "neuronal ceroid lipofuscinosis 13", "description": "A neuronal ceroid lipofuscinosis that is characterized by autosomal recessive inheritance with adult onset of progressive cognitive decline and motor dysfunction leading to dementia and often early death and has_material_basis_in homozygous or compound heterozygous mutation in the CTSF gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0110727", "evidence": [ { "id": "0110727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110727" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VN93", "url": "https://www.uniprot.org/uniprotkb/Q9VN93" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VN93", "url": "https://www.uniprot.org/uniprotkb/Q9VN93" } ], "pmid": "" }, { "name": "perivitelline space", "id": "GO:0098595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098595", "evidence": [ { "database": "UniProtKB", "id": "Q9VN93", "url": "https://www.uniprot.org/uniprotkb/Q9VN93" } ], "pmid": "" }, { "name": "fusome", "id": "GO:0045169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045169", "evidence": [ { "database": "UniProtKB", "id": "Q9VN93", "url": "https://www.uniprot.org/uniprotkb/Q9VN93" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "Q9VN93", "url": "https://www.uniprot.org/uniprotkb/Q9VN93" } ], "pmid": "" }, { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "Q9VN93", "url": "https://www.uniprot.org/uniprotkb/Q9VN93" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "Q9VN93", "url": "https://www.uniprot.org/uniprotkb/Q9VN93" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VN93-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Asn151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 151, "start_aa": "Asn", "end_pos": 151, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn151", "evidence": [ { "id": "Q9VN93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN93#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN93-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Asn492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 492, "start_aa": "Asn", "end_pos": 492, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn492", "evidence": [ { "id": "Q9VN93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN93#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VN93-1", "start_pos": "510", "end_pos": "510", "site_lbl": "Asn510", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 510, "start_aa": "Asn", "end_pos": 510, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn510", "evidence": [ { "id": "Q9VN93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN93#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VNH6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 985, "chemical_mass": 111667.0, "gene_names": "Sec8;CG2095;Dmel\\CG2095;Sec8p;Sec8;dsec8;fun;sec8", "protein_name": "Exocyst complex component 4", "disease": [], "cellular_component": [ { "name": "growth cone membrane", "id": "GO:0032584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032584", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "basal plasma membrane", "id": "GO:0009925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009925", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "rhabdomere", "id": "GO:0016028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016028", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" } ], "biological_process": [ { "name": "synaptic vesicle targeting", "id": "GO:0016080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016080", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "regulation of synapse structure or activity", "id": "GO:0050803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050803", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "positive regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045887", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "actomyosin contractile ring contraction", "id": "GO:0000916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000916", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "meiotic spindle organization", "id": "GO:0000212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000212", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "synaptic vesicle docking", "id": "GO:0016081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016081", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "meiosis I cytokinesis", "id": "GO:0007110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007110", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "meiosis II cytokinesis", "id": "GO:0007111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007111", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VNH6-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Ser235", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VNH6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VNH6" } ] } ] }, { "uniprot_canonical_ac": "Q9VNH6-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Ser456", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VNH6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VNH6" } ] } ] }, { "uniprot_canonical_ac": "Q9VNH6-1", "start_pos": "459", "end_pos": "459", "site_lbl": "Ser459", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VNH6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VNH6" } ] } ] }, { "uniprot_canonical_ac": "Q9VNH6-1", "start_pos": "682", "end_pos": "682", "site_lbl": "Ser682", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VNH6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VNH6" } ] } ] }, { "uniprot_canonical_ac": "Q9VNH6-1", "start_pos": "686", "end_pos": "686", "site_lbl": "Ser686", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VNH6", "url": "https://www.uniprot.org/uniprotkb/Q9VNH6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VNH6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VNH6" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VNJ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1218, "chemical_mass": 138979.0, "gene_names": "disp;CG2019;Disp;Dmel\\CG2019;anon-WO0146227.1;disp", "protein_name": "Protein dispatched", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "pmid": "" }, { "name": "cytoneme", "id": "GO:0035230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035230", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "pmid": "" } ], "biological_process": [ { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "pmid": "" }, { "name": "germ cell migration", "id": "GO:0008354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008354", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "pmid": "" }, { "name": "patched ligand maturation", "id": "GO:0007225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007225", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "pmid": "" }, { "name": "segment polarity determination", "id": "GO:0007367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007367", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "pmid": "" }, { "name": "wing disc pattern formation", "id": "GO:0035222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035222", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "1062", "end_pos": "1062", "site_lbl": "Thr1062", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1062, "start_aa": "Thr", "end_pos": 1062, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1062", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "127", "end_pos": "127", "site_lbl": "Asn127", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 127, "start_aa": "Asn", "end_pos": 127, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn127", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Asn176", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 176, "start_aa": "Asn", "end_pos": 176, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn176", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Asn197", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 197, "start_aa": "Asn", "end_pos": 197, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn197", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Asn264", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 264, "start_aa": "Asn", "end_pos": 264, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn264", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "319", "end_pos": "319", "site_lbl": "Asn319", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 319, "start_aa": "Asn", "end_pos": 319, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn319", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" }, { "id": "6TBU", "database": "PDB", "url": "https://www.rcsb.org/structure/6TBU" }, { "id": "6TBU", "database": "PDB", "url": "https://www.rcsb.org/structure/6TBU" }, { "id": "6TD6", "database": "PDB", "url": "https://www.rcsb.org/structure/6TD6" }, { "id": "6TD6", "database": "PDB", "url": "https://www.rcsb.org/structure/6TD6" }, { "id": "6TBU|A|319", "database": "", "url": "" }, { "id": "6TD6|A|319", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "388", "end_pos": "388", "site_lbl": "Asn388", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 388, "start_aa": "Asn", "end_pos": 388, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn388", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" }, { "id": "17893096", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/17893096" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "767", "end_pos": "767", "site_lbl": "Asn767", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 767, "start_aa": "Asn", "end_pos": 767, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn767", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "883", "end_pos": "883", "site_lbl": "Asn883", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 883, "start_aa": "Asn", "end_pos": 883, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn883", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "891", "end_pos": "891", "site_lbl": "Asn891", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 891, "start_aa": "Asn", "end_pos": 891, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn891", "evidence": [ { "id": "Q9VNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VNJ5-1", "start_pos": "1030", "end_pos": "1030", "site_lbl": "Asp1030", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of function; when associated with 516-A-A-517.", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" }, { "database": "PubMed", "id": "12372301", "url": "https://glygen.org/publication/PubMed/12372301" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Loss of function; when associated with 517-N-N-517.", "evidence": [ { "database": "UniProtKB", "id": "Q9VNJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VNJ5" }, { "database": "PubMed", "id": "12372301", "url": "https://glygen.org/publication/PubMed/12372301" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VNL4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNL4", "url": "https://www.uniprot.org/uniprotkb/Q9VNL4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 454, "chemical_mass": 50164.0, "gene_names": "31559;CG11461;CG15584;CG31559;Dmel\\CG31559", "protein_name": "Glutaredoxin domain-containing cysteine-rich protein CG31559", "disease": [ { "disease_id": "DOID:0110483", "name": "autosomal recessive nonsyndromic deafness 25", "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with moderate to profound, progressive hearing loss and has_material_basis_in mutation in the GRXCR1 gene on chromosome 4p13.", "url": "https://disease-ontology.org/term/DOID:0110483", "evidence": [ { "id": "0110483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110483" } ], "weight": 0.0 } ], "biological_process": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "Q9VNL4", "url": "https://www.uniprot.org/uniprotkb/Q9VNL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VNV3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 727, "chemical_mass": 80869.0, "gene_names": "Ddx1;CG9054;DDX1;Dbp79E;Ddx1;DmDDX1;DmRH12;Dmel\\CG9054;anon-79E", "protein_name": "ATP-dependent RNA helicase Ddx1", "disease": [], "molecular_function": [ { "name": "DNA/RNA helicase activity", "id": "GO:0033677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033677", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "nuclease activity", "id": "GO:0004518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004518", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "tRNA-splicing ligase complex", "id": "GO:0072669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072669", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "Q9VNV3", "url": "https://www.uniprot.org/uniprotkb/Q9VNV3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VNV3-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 87, "start_aa": "Thr", "end_pos": 87, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr87", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VNZ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1486, "chemical_mass": 165886.0, "gene_names": "Als2;ALS2;Als2;CG7158;Dmel\\CG7158;dALS2", "protein_name": "Alsin homolog", "disease": [ { "disease_id": "DOID:0060194", "name": "amyotrophic lateral sclerosis type 2", "description": "An amyotrophic lateral sclerosis that has_material_basis_in mutation in the alsin gene on chromosome 2.", "url": "https://disease-ontology.org/term/DOID:0060194", "evidence": [ { "id": "0060194", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060194" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of Rab protein signal transduction", "id": "GO:0032483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032483", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" }, { "name": "early endosome to late endosome transport", "id": "GO:0045022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" }, { "name": "melanotic encapsulation of foreign target", "id": "GO:0035011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035011", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VNZ8-1", "start_pos": "1425", "end_pos": "1425", "site_lbl": "Pro1425", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "Reduced GEF activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" }, { "database": "PubMed", "id": "24702731", "url": "https://glygen.org/publication/PubMed/24702731" } ] } ] }, { "uniprot_canonical_ac": "Q9VNZ8-1", "start_pos": "1439", "end_pos": "1439", "site_lbl": "Leu1439", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Reduced GEF activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ8" }, { "database": "PubMed", "id": "24702731", "url": "https://glygen.org/publication/PubMed/24702731" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VP61-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 670, "chemical_mass": 75946.0, "gene_names": "AcCoAS;ACS;ACeCS1;AcCoAS;AcCoAs;BEST:GH28401;CG9390;Dmel\\CG9390;acs;dACS", "protein_name": "Acetyl-coenzyme A synthetase", "disease": [ { "disease_id": "DOID:0050567", "name": "orofacial cleft", "description": "A physical disorder that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development.", "url": "https://disease-ontology.org/term/DOID:0050567", "evidence": [ { "id": "0050567", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050567" } ], "weight": 0.0 }, { "disease_id": "DOID:11981", "name": "morbid obesity", "description": "", "url": "https://disease-ontology.org/term/DOID:11981", "evidence": [ { "id": "11981", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11981" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:3319", "name": "lymphangioleiomyomatosis", "description": "A lung disease that is characterized by progressive cystic destruction of the lung and lymphatic abnormalities, frequently associated with renal angiomyolipomas.", "url": "https://disease-ontology.org/term/DOID:3319", "evidence": [ { "id": "3319", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3319" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "pmid": "" }, { "name": "AMP binding", "id": "GO:0016208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016208", "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "pmid": "" }, { "name": "acetate-CoA ligase activity", "id": "GO:0003987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003987", "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "pmid": "" } ], "biological_process": [ { "name": "behavioral response to ethanol", "id": "GO:0048149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048149", "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "pmid": "" }, { "name": "acetyl-CoA biosynthetic process", "id": "GO:0006085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006085", "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "pmid": "" }, { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "pmid": "" }, { "name": "acetyl-CoA biosynthetic process from acetate", "id": "GO:0019427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019427", "evidence": [ { "database": "UniProtKB", "id": "Q9VP61", "url": "https://www.uniprot.org/uniprotkb/Q9VP61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VPC0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 952, "chemical_mass": 108838.0, "gene_names": "Pitslre;CG4268;Dmel\\CG4268;Gat;Gta;PITSLRE;PitsIre;Pitslre;cdk11;group 3;pitslre", "protein_name": "Serine/threonine-protein kinase PITSLRE", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of antimicrobial peptide production", "id": "GO:0002225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002225", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "pmid": "" }, { "name": "positive regulation of Toll signaling pathway", "id": "GO:0045752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045752", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VPC0-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Ser439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VPC0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VPC0" } ] } ] }, { "uniprot_canonical_ac": "Q9VPC0-1", "start_pos": "442", "end_pos": "442", "site_lbl": "Ser442", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VPC0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VPC0" } ] } ] }, { "uniprot_canonical_ac": "Q9VPC0-1", "start_pos": "447", "end_pos": "447", "site_lbl": "Tyr447", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VPC0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VPC0" } ] } ] }, { "uniprot_canonical_ac": "Q9VPC0-1", "start_pos": "449", "end_pos": "449", "site_lbl": "Ser449", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VPC0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VPC0" } ] } ] }, { "uniprot_canonical_ac": "Q9VPC0-1", "start_pos": "881", "end_pos": "881", "site_lbl": "Ser881", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VPC0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VPC0" } ] } ] }, { "uniprot_canonical_ac": "Q9VPC0-1", "start_pos": "886", "end_pos": "886", "site_lbl": "Ser886", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VPC0", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VPC0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VPC0" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VPH8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 489, "chemical_mass": 54406.0, "gene_names": "Rbbp5;CG5585;Dmel\\CG5585;RBBP5;RbBP5;Rbbp5;dRbbp5;rbbp5", "protein_name": "Retinoblastoma-binding protein 5 homolog", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" }, { "name": "MLL3/4 complex", "id": "GO:0044666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044666", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" }, { "name": "MLL1/2 complex", "id": "GO:0044665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044665", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "Q9VPH8", "url": "https://www.uniprot.org/uniprotkb/Q9VPH8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VPN2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 505, "chemical_mass": 56864.0, "gene_names": "Amnionless;Amnionless;Amn;BEST:CK02467;CG11592;CK02467;Dmel\\CG11592;dAMN;dAmn", "protein_name": "Protein amnionless", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:13382", "name": "megaloblastic anemia", "description": "A macrocytic anemia that is characterized by inhibition of DNA synthesis during red blood cell production.", "url": "https://disease-ontology.org/term/DOID:13382", "evidence": [ { "id": "13382", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13382" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 } ], "biological_process": [ { "name": "renal protein absorption", "id": "GO:0097017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097017", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" }, { "name": "nephrocyte filtration", "id": "GO:0097206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097206", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" } ], "molecular_function": [ { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN2", "url": "https://www.uniprot.org/uniprotkb/Q9VPN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VPQ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 354, "chemical_mass": 40212.0, "gene_names": "shv;CG4164;Dmel\\CG4164;shv", "protein_name": "DnaJ homolog shv", "disease": [ { "disease_id": "DOID:0060951", "name": "polycystic kidney disease 6", "description": "An autosomal dominant polycystic kidney disease characterized by the development of multiple small renal cysts and progression to renal insufficiency or end-stage renal disease (ESRD) most often after the sixth decade that has_material_basis_in heterozygous mutation in the DNAJB11 gene on chromosome 3q27.", "url": "https://disease-ontology.org/term/DOID:0060951", "evidence": [ { "id": "0060951", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060951" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "positive regulation of synapse maturation", "id": "GO:0090129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090129", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "positive regulation of integrin-mediated signaling pathway", "id": "GO:2001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001046", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "male germ-line stem cell population maintenance", "id": "GO:0036098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036098", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "germ-line stem-cell niche homeostasis", "id": "GO:0060250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060250", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" }, { "name": "misfolded protein binding", "id": "GO:0051787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051787", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VPQ2-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Asn260", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 260, "start_aa": "Asn", "end_pos": 260, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn260", "evidence": [ { "id": "Q9VPQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VPQ2-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Asn312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 312, "start_aa": "Asn", "end_pos": 312, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn312", "evidence": [ { "id": "Q9VPQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VPQ2-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Lys253", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "L", "comment": "Loss of activity. Decrease in focal adhesion kinase (FAK) phosphorylation and loss of cell spreading; when associated with V-255.", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" }, { "database": "PubMed", "id": "27191715", "url": "https://glygen.org/publication/PubMed/27191715" } ] } ] }, { "uniprot_canonical_ac": "Q9VPQ2-1", "start_pos": "255", "end_pos": "255", "site_lbl": "Asp255", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "V", "comment": "Loss of activity. Decrease in focal adhesion kinase (FAK) phosphorylation and loss of cell spreading; when associated with L-253.", "evidence": [ { "database": "UniProtKB", "id": "Q9VPQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VPQ2" }, { "database": "PubMed", "id": "27191715", "url": "https://glygen.org/publication/PubMed/27191715" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VPS5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 648, "chemical_mass": 68637.0, "gene_names": "Hsp60B;152031_at;CG2830;Dm21D;Dmel\\CG2830;HSP60B;Hsp60B;Hsp60b;Hsp60;Hsp64;anon-WO0140519.61;hsp60B;ms(2)06619;ms(2)21D", "protein_name": "60 kDa heat shock protein homolog 1, mitochondrial", "disease": [ { "disease_id": "DOID:0060789", "name": "hypomyelinating leukodystrophy 4", "description": "A hypomyelinating leukodystrophy characterized by autosomal recessive inheritance of hypotonia, nystagmus, psychomotor developmental delay, and severe hypomyelinating leukoencephalopathy that has_material_basis_in homozygous mutation in the HSPD1 gene on chromosome 2q33.", "url": "https://disease-ontology.org/term/DOID:0060789", "evidence": [ { "id": "0060789", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060789" } ], "weight": 0.0 }, { "disease_id": "DOID:0110766", "name": "hereditary spastic paraplegia 13", "description": "A hereditary spastic paraplegia that is characterized by a pure form of the disease with late onset and has_material_basis_in mutation in the HSPD1 gene on chromosome 2q33.", "url": "https://disease-ontology.org/term/DOID:0110766", "evidence": [ { "id": "0110766", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110766" } ], "weight": 0.0 }, { "disease_id": "DOID:10603", "name": "glucose intolerance", "description": "", "url": "https://disease-ontology.org/term/DOID:10603", "evidence": [ { "id": "10603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10603" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 }, { "disease_id": "DOID:12337", "name": "varicocele", "description": "", "url": "https://disease-ontology.org/term/DOID:12337", "evidence": [ { "id": "12337", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12337" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:13544", "name": "low tension glaucoma", "description": "An open-angle glaucoma characterized by increased intrinsic resistance to aqueous outflow without known secondary causes, an anatomically narrow anterior chamber angle, or elevated intraocular pressure compared to the average population. Normal tension glaucoma has_symptom progressive decreased vision and progressive loss of peripheral vision.", "url": "https://disease-ontology.org/term/DOID:13544", "evidence": [ { "id": "13544", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13544" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs.", "url": "https://disease-ontology.org/term/DOID:2476", "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:676", "name": "systemic juvenile rheumatoid arthritis", "description": "A rheumatoid arthritis that involves an autoimmune disease onset in children under 16 which attacks the healthy cells and tissue of located_in joint.", "url": "https://disease-ontology.org/term/DOID:676", "evidence": [ { "id": "676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:676" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9663", "name": "aphthous stomatitis", "description": "A stomatitis characterized by the repeated formation of benign and non-contagious mouth ulcers.", "url": "https://disease-ontology.org/term/DOID:9663", "evidence": [ { "id": "9663", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9663" } ], "weight": 0.0 } ], "biological_process": [ { "name": "protein import into mitochondrial intermembrane space", "id": "GO:0045041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045041", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" }, { "name": "apoptotic mitochondrial changes", "id": "GO:0008637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008637", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" }, { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" }, { "name": "mitochondrial unfolded protein response", "id": "GO:0034514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034514", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" }, { "name": "ATP-dependent protein folding chaperone", "id": "GO:0140662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140662", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VPS5", "url": "https://www.uniprot.org/uniprotkb/Q9VPS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VPS5-1", "start_pos": "48", "end_pos": "48", "site_lbl": "Thr48", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VPS5-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 621, "start_aa": "Thr", "end_pos": 621, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr621", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VPT8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPT8", "url": "https://www.uniprot.org/uniprotkb/Q9VPT8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 296, "chemical_mass": 33500.0, "gene_names": "Clp;CG3642;CLP;CPSF30;Clp;Cpsf30;Dmel\\CG3642;Ssb-c6a;c6a;clp", "protein_name": "Cleavage and polyadenylation specificity factor subunit 4", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT8", "url": "https://www.uniprot.org/uniprotkb/Q9VPT8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT8", "url": "https://www.uniprot.org/uniprotkb/Q9VPT8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT8", "url": "https://www.uniprot.org/uniprotkb/Q9VPT8" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT8", "url": "https://www.uniprot.org/uniprotkb/Q9VPT8" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT8", "url": "https://www.uniprot.org/uniprotkb/Q9VPT8" } ], "pmid": "" } ], "cellular_component": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT8", "url": "https://www.uniprot.org/uniprotkb/Q9VPT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VPW1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPW1", "url": "https://www.uniprot.org/uniprotkb/Q9VPW1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 854, "chemical_mass": 98376.0, "gene_names": "ast;Ast;CG4426;Dmel\\CG4426;S[r];Star/asteroid;ast", "protein_name": "Protein asteroid", "disease": [ { "disease_id": "DOID:0112182", "name": "mismatch repair cancer syndrome", "description": "A syndrome characterized by predisposition for development of a broad spectrum of malignancies during childhood, including mainly brain, hematological and gastrointestinal cancers that has_material_basis_in homozygous or compound heterozygous mutation in the mismatch repair genes MLH1, MSH2, MSH6, or PMS2 on chromosomes 3p22.2, 2p21-p16, 2p16.3, and 7p22.1, respectively.", "url": "https://disease-ontology.org/term/DOID:0112182", "evidence": [ { "id": "0112182", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112182" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 } ], "biological_process": [ { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW1", "url": "https://www.uniprot.org/uniprotkb/Q9VPW1" } ], "pmid": "" }, { "name": "compound eye photoreceptor fate commitment", "id": "GO:0001752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001752", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW1", "url": "https://www.uniprot.org/uniprotkb/Q9VPW1" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW1", "url": "https://www.uniprot.org/uniprotkb/Q9VPW1" } ], "pmid": "" }, { "name": "larval somatic muscle development", "id": "GO:0007526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007526", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW1", "url": "https://www.uniprot.org/uniprotkb/Q9VPW1" } ], "pmid": "" }, { "name": "imaginal disc-derived wing vein morphogenesis", "id": "GO:0008586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008586", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW1", "url": "https://www.uniprot.org/uniprotkb/Q9VPW1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VPW1-1", "start_pos": "798", "end_pos": "798", "site_lbl": "Thr798", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 798, "start_aa": "Thr", "end_pos": 798, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr798", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VQD2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 506, "chemical_mass": 57362.0, "gene_names": "Cyp309a1;309a1;CG9964;CYP309A1;Cyp309A1;Cyp309a1;Dmel\\CG9964", "protein_name": "Probable cytochrome P450 309a1", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VQD2-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Thr75", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VQD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VQD2" } ] } ] }, { "uniprot_canonical_ac": "Q9VQD2-1", "start_pos": "78", "end_pos": "78", "site_lbl": "Thr78", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VQD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VQD2" } ] } ] }, { "uniprot_canonical_ac": "Q9VQD2-1", "start_pos": "81", "end_pos": "81", "site_lbl": "Thr81", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD2", "url": "https://www.uniprot.org/uniprotkb/Q9VQD2" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VQD2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VQD2" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VQD6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 381, "chemical_mass": 43310.0, "gene_names": "Elba2;CG9883;Dmel\\CG9883;Elba2;Elba", "protein_name": "Early boundary activity protein 2", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "chromatin silencing complex", "id": "GO:0005677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005677", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "polytene chromosome band", "id": "GO:0005704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005704", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" }, { "name": "heterochromatin boundary formation", "id": "GO:0033696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033696", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD6", "url": "https://www.uniprot.org/uniprotkb/Q9VQD6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VQF7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQF7", "url": "https://www.uniprot.org/uniprotkb/Q9VQF7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 152, "chemical_mass": 15460.0, "gene_names": "Bacc;Bacc;CG9894;Dmel\\CG9894;anon-EST:Liang-2.54;bacc;clone 2.54", "protein_name": "Bacchus", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VQF7", "url": "https://www.uniprot.org/uniprotkb/Q9VQF7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9VQF7", "url": "https://www.uniprot.org/uniprotkb/Q9VQF7" } ], "pmid": "" } ], "biological_process": [ { "name": "behavioral response to ethanol", "id": "GO:0048149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048149", "evidence": [ { "database": "UniProtKB", "id": "Q9VQF7", "url": "https://www.uniprot.org/uniprotkb/Q9VQF7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VQG4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 306, "chemical_mass": 32952.0, "gene_names": "colt;CACT;CG3057;Colt;Dmel\\CG3057;colt", "protein_name": "Congested-like trachea protein", "disease": [ { "disease_id": "DOID:0111585", "name": "carnitine-acylcarnitine translocase deficiency", "description": "A lipid metabolism disorder characterized by impaired long-chain fatty acid ozidation resulting in fasting-induced hypoketotic hypoglycemia, hyperammonemia, elevated creatine kinase and transaminases, dicarboxylic aciduria, very low free carnitine and abnormal acylcarnitine profile with marked elevation of the long-chain acylcarnitines that has_material_basis_in homozygous or compound heterozygous mutation in the SLC25A20 gene on chromosome 3p21.31.", "url": "https://disease-ontology.org/term/DOID:0111585", "evidence": [ { "id": "0111585", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111585" } ], "weight": 0.0 }, { "disease_id": "DOID:3146", "name": "lipid metabolism disorder", "description": "An inherited metabolic disorder that involves the creation and degradation of lipids.", "url": "https://disease-ontology.org/term/DOID:3146", "evidence": [ { "id": "3146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3146" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial envelope", "id": "GO:0005740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005740", "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial transport", "id": "GO:0006839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006839", "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "pmid": "" }, { "name": "epithelial cell morphogenesis", "id": "GO:0003382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003382", "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "pmid": "" }, { "name": "carnitine transmembrane transport", "id": "GO:1902603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902603", "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "pmid": "" }, { "name": "liquid clearance, open tracheal system", "id": "GO:0035002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035002", "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "pmid": "" } ], "molecular_function": [ { "name": "O-acyl-L-carnitine transmembrane transporter activity", "id": "GO:0015227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015227", "evidence": [ { "database": "UniProtKB", "id": "Q9VQG4", "url": "https://www.uniprot.org/uniprotkb/Q9VQG4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VQQ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 894, "chemical_mass": 100729.0, "gene_names": "Sec5;CG8843;Dmel\\CG8843;SEC5;Sec-5;Sec5p;Sec5;dsec5;sec5", "protein_name": "Exocyst complex component 2", "disease": [], "biological_process": [ { "name": "synaptic vesicle targeting", "id": "GO:0016080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016080", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "protein localization to cell cortex", "id": "GO:0072697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072697", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "anterograde axonal protein transport", "id": "GO:0099641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099641", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "transcytosis", "id": "GO:0045056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045056", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "oocyte development", "id": "GO:0048599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048599", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "regulation of synapse maturation", "id": "GO:0090128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090128", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "protein localization to adherens junction", "id": "GO:0071896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071896", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "synaptic vesicle docking", "id": "GO:0016081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016081", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "positive regulation of Golgi vesicle fusion to target membrane", "id": "GO:0048215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048215", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "cellularization", "id": "GO:0007349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007349", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "branch fusion, open tracheal system", "id": "GO:0035147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035147", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "annulate lamellae", "id": "GO:0005642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005642", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "subapical complex", "id": "GO:0035003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035003", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" }, { "name": "rhabdomere", "id": "GO:0016028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016028", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VR09-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 106, "chemical_mass": 11841.0, "gene_names": "HP6;CG15636;Dmel\\CG15636;Dmel_CG15636;HP6;UMBREA;UMB;Umbrea;umbrea", "protein_name": "", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "chromocenter", "id": "GO:0010369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010369", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" } ], "biological_process": [ { "name": "telomere capping", "id": "GO:0016233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016233", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "female meiotic nuclear division", "id": "GO:0007143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007143", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "Q9VR09", "url": "https://www.uniprot.org/uniprotkb/Q9VR09" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VR17-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 363, "chemical_mass": 41583.0, "gene_names": "Elba1;Bsg25A;CG12205;Dmel\\CG12205;Elba1;Elba;anon-EST:Liang-1.70;bsg25A;clone 1.70;elba1", "protein_name": "Early boundary activity protein 1", "disease": [], "molecular_function": [ { "name": "chromatin insulator sequence binding", "id": "GO:0043035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043035", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" }, { "name": "chromatin silencing complex", "id": "GO:0005677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005677", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" }, { "name": "heterochromatin boundary formation", "id": "GO:0033696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033696", "evidence": [ { "database": "UniProtKB", "id": "Q9VR17", "url": "https://www.uniprot.org/uniprotkb/Q9VR17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VR82-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 481, "chemical_mass": 55661.0, "gene_names": "Inx6;CG17063;Dm-inx6;Dmel\\CG17063;FBpp0077031;Inx6;inx-6;inx6;prp6", "protein_name": "Innexin inx6", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "pmid": "" }, { "name": "gap junction", "id": "GO:0005921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005921", "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "pmid": "" } ], "biological_process": [ { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "pmid": "" }, { "name": "intercellular transport", "id": "GO:0010496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010496", "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "pmid": "" }, { "name": "medium-term memory", "id": "GO:0072375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072375", "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "pmid": "" } ], "molecular_function": [ { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "Q9VR82", "url": "https://www.uniprot.org/uniprotkb/Q9VR82" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VR91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4912, "chemical_mass": 529997.0, "gene_names": "HERC2;AF189221.1;CG11734;Dmel\\CG11734;HERC2;dHERC2", "protein_name": "Probable E3 ubiquitin-protein ligase HERC2", "disease": [ { "disease_id": "DOID:0081203", "name": "autosomal recessive intellectual developmental disorder 38", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the HERC2 gene on chromosome 15q13.", "url": "https://disease-ontology.org/term/DOID:0081203", "evidence": [ { "id": "0081203", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081203" } ], "weight": 0.0 }, { "disease_id": "DOID:10123", "name": "pigmentation disease", "description": "A skin disease that is characterized by discoloration of the skin.", "url": "https://disease-ontology.org/term/DOID:10123", "evidence": [ { "id": "10123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10123" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VR91-1", "start_pos": "2546", "end_pos": "2546", "site_lbl": "Thr2546", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2546, "start_aa": "Thr", "end_pos": 2546, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2546", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VR91-1", "start_pos": "1776", "end_pos": "1776", "site_lbl": "Thr1776", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VR91", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VR91", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VR91" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VRB3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRB3", "url": "https://www.uniprot.org/uniprotkb/Q9VRB3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 520, "chemical_mass": 60763.0, "gene_names": "Cyp6v1;6v1;CG1829;Cyp6v1;Dmel\\CG1829;Dmel_CG1829", "protein_name": "Probable cytochrome P450 6v1", "disease": [ { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:0080630", "name": "B-lymphoblastic leukemia/lymphoma", "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow.", "url": "https://disease-ontology.org/term/DOID:0080630", "evidence": [ { "id": "0080630", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080630" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10825", "name": "essential hypertension", "description": "A hypertension with no known cause. It is the most common type of hypertension.", "url": "https://disease-ontology.org/term/DOID:10825", "evidence": [ { "id": "10825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10825" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:5773", "name": "oral submucous fibrosis", "description": "A mouth disease that is characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues.", "url": "https://disease-ontology.org/term/DOID:5773", "evidence": [ { "id": "5773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5773" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VRB3", "url": "https://www.uniprot.org/uniprotkb/Q9VRB3" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VRB3", "url": "https://www.uniprot.org/uniprotkb/Q9VRB3" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VRB3", "url": "https://www.uniprot.org/uniprotkb/Q9VRB3" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VRB3", "url": "https://www.uniprot.org/uniprotkb/Q9VRB3" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VRB3", "url": "https://www.uniprot.org/uniprotkb/Q9VRB3" } ], "pmid": "" } ], "biological_process": [ { "name": "response to DDT", "id": "GO:0046680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046680", "evidence": [ { "database": "UniProtKB", "id": "Q9VRB3", "url": "https://www.uniprot.org/uniprotkb/Q9VRB3" } ], "pmid": "" }, { "name": "insecticide catabolic process", "id": "GO:0046701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046701", "evidence": [ { "database": "UniProtKB", "id": "Q9VRB3", "url": "https://www.uniprot.org/uniprotkb/Q9VRB3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VRG7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 243, "chemical_mass": 28486.0, "gene_names": "Ctdnep1;Dd;20151539;BcDNA:LD08201;CG1696;Ctdnep1;DD;Dd;Dmel\\CG1696;Dmel_CG1696;anon-WO03040301.167;ddd;l(1)G0269", "protein_name": "CTD nuclear envelope phosphatase 1 homolog", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase complex", "id": "GO:0008287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008287", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "Nem1-Spo7 phosphatase complex", "id": "GO:0071595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071595", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "TIM23 mitochondrial import inner membrane translocase complex", "id": "GO:0005744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005744", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "phosphatase activator activity", "id": "GO:0019211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019211", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "positive regulation of triglyceride biosynthetic process", "id": "GO:0010867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010867", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "imaginal disc-derived wing vein specification", "id": "GO:0007474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007474", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "nuclear membrane biogenesis", "id": "GO:0101025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101025", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "membrane biogenesis", "id": "GO:0044091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044091", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "nuclear membrane organization", "id": "GO:0071763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071763", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG7", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VRJ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 726, "chemical_mass": 82534.0, "gene_names": "Gen;BcDNA:GM10765;CG10670;DmGEN;DmGen;Dmel\\CG10670;GEN;Gen;mus324", "protein_name": "Flap endonuclease GEN", "disease": [], "molecular_function": [ { "name": "single-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008310", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "DNA endonuclease activity", "id": "GO:0004520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004520", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "double-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008311", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "5'-3' DNA exonuclease activity", "id": "GO:0035312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035312", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "crossover junction DNA endonuclease activity", "id": "GO:0008821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008821", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "5'-flap endonuclease activity", "id": "GO:0017108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017108", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRJ0-1", "start_pos": "439", "end_pos": "439", "site_lbl": "Tyr439", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VRJ0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VRJ0" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VRJ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 108, "chemical_mass": 12082.0, "gene_names": "CG10674;Dmel\\CG10674", "protein_name": "Protein Asterix", "disease": [], "biological_process": [ { "name": "protein insertion into ER membrane", "id": "GO:0045048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045048", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ8" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "Q9VRJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VRM7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 543, "chemical_mass": 62448.0, "gene_names": "spo;307a1;CG10594;CYP307A1-Dm;CYP307A1;Cyp307a1;Dmel\\CG10594;Dmspo;Spo;spo", "protein_name": "Cytochrome P450 307a1", "disease": [ { "disease_id": "DOID:0050083", "name": "Keshan disease", "description": "A nutritional deficiency that is disease characterized by a cardiomyopathy secondary to selenium deficiency.", "url": "https://disease-ontology.org/term/DOID:0050083", "evidence": [ { "id": "0050083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050083" } ], "weight": 0.0 }, { "disease_id": "DOID:0050811", "name": "congenital adrenal hyperplasia", "description": "A steroid inherited metabolic disorder that is characterized by adrenal insufficiency and variable degrees of hyper or hypo androgyny manifestations resulting from steroidogenic enzyme deficiency.", "url": "https://disease-ontology.org/term/DOID:0050811", "evidence": [ { "id": "0050811", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050811" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0060673", "name": "Peters anomaly", "description": "A corneal disease characterized by a central corneal leukoma and absence of the posterior corneal stroma and Descemet membrane that has_material_basis_in mutation in the PAX6 gene on chromosome 11p13, the PITX2 gene on chromosome 4q25, the CYP1B1 gene on chromosome 2p22.2, or the FOXC1 gene on chromosome 6p25.3.", "url": "https://disease-ontology.org/term/DOID:0060673", "evidence": [ { "id": "0060673", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060673" } ], "weight": 0.0 }, { "disease_id": "DOID:0080611", "name": "anterior segment dysgenesis 6", "description": "An anterior segment dysgenesis that has_material_basis_in compound heterozygous mutation in the CYP1B1 gene on chromosome 2p22.", "url": "https://disease-ontology.org/term/DOID:0080611", "evidence": [ { "id": "0080611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080611" } ], "weight": 0.0 }, { "disease_id": "DOID:10211", "name": "cholelithiasis", "description": "", "url": "https://disease-ontology.org/term/DOID:10211", "evidence": [ { "id": "10211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10211" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1070", "name": "primary open angle glaucoma", "description": "An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.", "url": "https://disease-ontology.org/term/DOID:1070", "evidence": [ { "id": "1070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1070" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10892", "name": "hypospadias", "description": "A physical disorder characterized by an abnormally placed urethral opening on the underside of the penis or on the perineum.", "url": "https://disease-ontology.org/term/DOID:10892", "evidence": [ { "id": "10892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10892" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11211", "name": "buphthalmos", "description": "A hydrophthalmos characterized by early onset glaucoma in one or both eyes with elevated intraocular pressure, increased corneal diameter, and swelling of the globe and has_symptom early vision loss, photophobia, blepharospasm, tearing, increased corneal diameter, increased corneal thickness, and enlarged globe. Buphthalmos is caused by severe congenital defects of the trabecular meshwork and anterior chamber angle that block aqueous outflow and raises intraocular pressure, leading to optic nerve atrophy and early vision loss.", "url": "https://disease-ontology.org/term/DOID:11211", "evidence": [ { "id": "11211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11211" } ], "weight": 0.0 }, { "disease_id": "DOID:11212", "name": "hydrophthalmos", "description": "A primary congenital glaucoma characterized by early onset glaucoma in one or both eyes with elevated intraocular pressure and increased corneal diameter and has_symptom early vision loss, increased corneal diameter, and increased corneal thickness. Hydrophthalmus is caused by congenital defects of the trabecular meshwork and anterior chamber angle that block aqueous outflow and raises intraocular pressure, leading to optic nerve atrophy and early vision loss.", "url": "https://disease-ontology.org/term/DOID:11212", "evidence": [ { "id": "11212", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11212" } ], "weight": 0.0 }, { "disease_id": "DOID:114", "name": "heart disease", "description": "A cardiovascular system disease that involves the heart.", "url": "https://disease-ontology.org/term/DOID:114", "evidence": [ { "id": "114", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:114" } ], "weight": 0.0 }, { "disease_id": "DOID:11476", "name": "osteoporosis", "description": "A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.", "url": "https://disease-ontology.org/term/DOID:11476", "evidence": [ { "id": "11476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11476" } ], "weight": 0.0 }, { "disease_id": "DOID:11612", "name": "polycystic ovary syndrome", "description": "An ovarian dysfunction that is characterized by hyperandrogenism, polycystic ovaries, hirsutism, oligomenorrhea or amenorrhea, anovulation and excessive body weight.", "url": "https://disease-ontology.org/term/DOID:11612", "evidence": [ { "id": "11612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11612" } ], "weight": 0.0 }, { "disease_id": "DOID:11836", "name": "clubfoot", "description": "A bone development disease where one or both are inclined inwards, axially rotated outwards, and pointing downwards with concomitant soft tissue abnormalities.", "url": "https://disease-ontology.org/term/DOID:11836", "evidence": [ { "id": "11836", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11836" } ], "weight": 0.0 }, { "disease_id": "DOID:11934", "name": "head and neck cancer", "description": "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx.", "url": "https://disease-ontology.org/term/DOID:11934", "evidence": [ { "id": "11934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11934" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.", "url": "https://disease-ontology.org/term/DOID:12361", "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ], "weight": 0.0 }, { "disease_id": "DOID:12894", "name": "Sjogren's syndrome", "description": "An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.", "url": "https://disease-ontology.org/term/DOID:12894", "evidence": [ { "id": "12894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12894" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3121", "name": "gallbladder cancer", "description": "A biliary tract cancer that is located_in the gallbladder.", "url": "https://disease-ontology.org/term/DOID:3121", "evidence": [ { "id": "3121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3121" } ], "weight": 0.0 }, { "disease_id": "DOID:3132", "name": "porphyria cutanea tarda", "description": "An acute porphyria characterized by painful, blistering skin lesions that develop on sun-exposed skin.", "url": "https://disease-ontology.org/term/DOID:3132", "evidence": [ { "id": "3132", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3132" } ], "weight": 0.0 }, { "disease_id": "DOID:3458", "name": "breast adenocarcinoma", "description": "A breast carcinoma that originates in the milk ducts and/or lobules (glandular tissue) of the breast.", "url": "https://disease-ontology.org/term/DOID:3458", "evidence": [ { "id": "3458", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3458" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4607", "name": "biliary tract cancer", "description": "A hepatobiliary system cancer that results_in malignant growth located_in the gallbladder or located_in the bile duct.", "url": "https://disease-ontology.org/term/DOID:4607", "evidence": [ { "id": "4607", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4607" } ], "weight": 0.0 }, { "disease_id": "DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:5041", "evidence": [ { "id": "5041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5041" } ], "weight": 0.0 }, { "disease_id": "DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.", "url": "https://disease-ontology.org/term/DOID:552", "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6132", "name": "bronchitis", "description": "A bronchial disease that is an inflammation of the bronchial tubes. It is caused by bacteria and viruses. The disease has_symptom cough with mucus, has_symptom shortness of breath, has_symptom low fever and has_symptom chest tightness.", "url": "https://disease-ontology.org/term/DOID:6132", "evidence": [ { "id": "6132", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6132" } ], "weight": 0.0 }, { "disease_id": "DOID:6196", "name": "reactive arthritis", "description": "An arthritis that is an autoimmune disease which develops due to an infection located elsewhere in the body.", "url": "https://disease-ontology.org/term/DOID:6196", "evidence": [ { "id": "6196", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6196" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage.", "url": "https://disease-ontology.org/term/DOID:7147", "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:824", "name": "periodontitis", "description": "", "url": "https://disease-ontology.org/term/DOID:824", "evidence": [ { "id": "824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:824" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:8618", "name": "oral cavity cancer", "description": "A gastrointestinal system cancer that is located_in the oral cavity.", "url": "https://disease-ontology.org/term/DOID:8618", "evidence": [ { "id": "8618", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8618" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:9008", "name": "psoriatic arthritis", "description": "An arthritis that is characterized by joint inflammation that usually occurs in combination with psoriasis.", "url": "https://disease-ontology.org/term/DOID:9008", "evidence": [ { "id": "9008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9008" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cuticle development", "id": "GO:0042335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042335", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "embryonic digestive tract development", "id": "GO:0048566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048566", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "midgut development", "id": "GO:0007494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007494", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "ecdysone biosynthetic process", "id": "GO:0006697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006697", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "dorsal closure", "id": "GO:0007391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007391", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "head involution", "id": "GO:0008258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008258", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRM7-1", "start_pos": "219", "end_pos": "219", "site_lbl": "Ser219", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM7", "url": "https://www.uniprot.org/uniprotkb/Q9VRM7" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VRM7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VRM7" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VRP9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1044, "chemical_mass": 119060.0, "gene_names": "Bre1;BRE1;Bre-1;Bre1;CG10542;Dmel\\CG10542;Dmel_CG10542;EC3-8;bre-1;bre1;dBRE1;dBre1;l(3)01640", "protein_name": "E3 ubiquitin-protein ligase Bre1", "disease": [ { "disease_id": "DOID:12387", "name": "nephrogenic diabetes insipidus", "description": "A diabetes insipidus that is characterized by a complete or partial resistance of the kidneys to vasopressin (ADH).", "url": "https://disease-ontology.org/term/DOID:12387", "evidence": [ { "id": "12387", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12387" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "HULC complex", "id": "GO:0033503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033503", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" } ], "biological_process": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "positive regulation of cell differentiation", "id": "GO:0045597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045597", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "negative regulation of heterochromatin formation", "id": "GO:0031452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031452", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRP9-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Thr242", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VRP9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VRP9" } ] } ] }, { "uniprot_canonical_ac": "Q9VRP9-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VRP9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VRP9" } ] } ] }, { "uniprot_canonical_ac": "Q9VRP9-1", "start_pos": "632", "end_pos": "632", "site_lbl": "Ser632", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VRP9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VRP9" } ] } ] }, { "uniprot_canonical_ac": "Q9VRP9-1", "start_pos": "638", "end_pos": "638", "site_lbl": "Ser638", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP9", "url": "https://www.uniprot.org/uniprotkb/Q9VRP9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VRP9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VRP9" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VRQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 525, "chemical_mass": 58759.0, "gene_names": "PolE2;10489;CG10489;DNApol-epsilon58;DNApol-epsilon;DNApolE2;Dmel\\CG10489;POLE2;PolE2;Pole2;dpolepsilonp58;pol.epsilon 2", "protein_name": "DNA polymerase epsilon subunit 2", "disease": [], "cellular_component": [ { "name": "epsilon DNA polymerase complex", "id": "GO:0008622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008622", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of DNA endoreduplication", "id": "GO:0032877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032877", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" }, { "name": "DNA replication proofreading", "id": "GO:0045004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045004", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" }, { "name": "DNA endoreduplication", "id": "GO:0042023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042023", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" }, { "name": "positive regulation of cell cycle process", "id": "GO:0090068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090068", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" }, { "name": "mitotic DNA replication", "id": "GO:1902969", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902969", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRQ7-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Thr367", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 367, "start_aa": "Thr", "end_pos": 367, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr367", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VRY7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRY7", "url": "https://www.uniprot.org/uniprotkb/Q9VRY7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 659, "chemical_mass": 74025.0, "gene_names": "Rsph3;CG10099;CG14912;CG32392;Dmel\\CG32392;Dmel_CG32392;Rsph3;dRSPH3;rsp3", "protein_name": "", "disease": [ { "disease_id": "DOID:0110603", "name": "primary ciliary dyskinesia 32", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with near absence of radial spokes, respiratory distress in term neonates, impaired mucociliary clearance, chronic respiratory infections, bronchiectasis, and infertility and has_material_basis_in homozygous or compound heterozygous mutation in the RSPH3 gene on chromosome 6q25.", "url": "https://disease-ontology.org/term/DOID:0110603", "evidence": [ { "id": "0110603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110603" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VRY7", "url": "https://www.uniprot.org/uniprotkb/Q9VRY7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VRY7", "url": "https://www.uniprot.org/uniprotkb/Q9VRY7" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q9VRY7", "url": "https://www.uniprot.org/uniprotkb/Q9VRY7" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q9VRY7", "url": "https://www.uniprot.org/uniprotkb/Q9VRY7" } ], "pmid": "" } ], "biological_process": [ { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "Q9VRY7", "url": "https://www.uniprot.org/uniprotkb/Q9VRY7" } ], "pmid": "" }, { "name": "sperm individualization", "id": "GO:0007291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007291", "evidence": [ { "database": "UniProtKB", "id": "Q9VRY7", "url": "https://www.uniprot.org/uniprotkb/Q9VRY7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRY7-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Thr424", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 424, "start_aa": "Thr", "end_pos": 424, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr424", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VS05-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 676, "chemical_mass": 71063.0, "gene_names": "bin;BIN;Bin;CG18647;DmFoxF;Dmbin;Dmel\\CG18647;FOXF;FoxF;XIV;binI;bin;l(3)65CEe", "protein_name": "Forkhead box protein biniou", "disease": [ { "disease_id": "DOID:13042", "name": "persistent fetal circulation syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:13042", "evidence": [ { "id": "13042", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13042" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mesodermal cell fate commitment", "id": "GO:0001710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001710", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" }, { "name": "salivary gland morphogenesis", "id": "GO:0007435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007435", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9VS05", "url": "https://www.uniprot.org/uniprotkb/Q9VS05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VS50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1052, "chemical_mass": 117414.0, "gene_names": "eco;CG8598;Deco;Dmel\\CG8598;ECO;Eco1;Eco;deco;eco", "protein_name": "N-acetyltransferase eco", "disease": [ { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:5325", "name": "Roberts syndrome", "description": "A syndrome characterized by tetraphocomelia, craniofacial anomalies, growth retardation, intellectual disability, and cardiac and renal abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the ESCO2 gene on chromosome 8p21.1.", "url": "https://disease-ontology.org/term/DOID:5325", "evidence": [ { "id": "5325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5325" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein-lysine-acetyltransferase activity", "id": "GO:0061733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061733", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" } ], "pmid": "" }, { "name": "acetyltransferase activity", "id": "GO:0016407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016407", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VS50-1", "start_pos": "150", "end_pos": "150", "site_lbl": "Thr150", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 150, "start_aa": "Thr", "end_pos": 150, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr150", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VS50-1", "start_pos": "176", "end_pos": "176", "site_lbl": "Ser176", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VS50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VS50" } ] } ] }, { "uniprot_canonical_ac": "Q9VS50-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Ser177", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VS50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VS50" } ] } ] }, { "uniprot_canonical_ac": "Q9VS50-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Ser310", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VS50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VS50" } ] } ] }, { "uniprot_canonical_ac": "Q9VS50-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Ser312", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VS50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VS50" } ] } ] }, { "uniprot_canonical_ac": "Q9VS50-1", "start_pos": "314", "end_pos": "314", "site_lbl": "Ser314", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VS50", "url": "https://www.uniprot.org/uniprotkb/Q9VS50" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VS50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VS50" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VSA3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 419, "chemical_mass": 45871.0, "gene_names": "Mcad;ACAD;CG 12262;CG12262;Dmel\\CG12262;MCAD;Mcad;mcad", "protein_name": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "disease": [ { "disease_id": "DOID:0080153", "name": "medium chain acyl-CoA dehydrogenase deficiency", "description": "A lipid metabolism disorder that is characterized by a deficiency of the enzyme medium chain acyl-CoA dehydrogenase that results in the inability to convert medium chain fatty acids to energy, particularly during fasting.", "url": "https://disease-ontology.org/term/DOID:0080153", "evidence": [ { "id": "0080153", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080153" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "acyl-CoA dehydrogenase activity", "id": "GO:0003995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003995", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" }, { "name": "medium-chain fatty acyl-CoA dehydrogenase activity", "id": "GO:0070991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070991", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation using acyl-CoA dehydrogenase", "id": "GO:0033539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033539", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" }, { "name": "medium-chain fatty acid catabolic process", "id": "GO:0051793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051793", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VSA3-1", "start_pos": "347", "end_pos": "347", "site_lbl": "Ser347", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" }, { "database": "iPTMnet", "id": "Q9VSA3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VSA3" }, { "database": "PubMed", "id": "29563254", "url": "https://glygen.org/publication/PubMed/29563254" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Prevents phosphorylation by Pink1. Does not rescue climbing and flight defects in Pink1 mutants.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" }, { "database": "PubMed", "id": "29563254", "url": "https://glygen.org/publication/PubMed/29563254" } ] }, { "sequence_org": "S", "sequence_mut": "DD", "comment": "Phosphomimetic mutant that fully rescues climbing defects and significantly improves flight defects, and thorax and wing posture phenotypes in Pink1 mutants. No effect on acyl-CoA dehydrogenase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" }, { "database": "PubMed", "id": "29563254", "url": "https://glygen.org/publication/PubMed/29563254" } ] }, { "sequence_org": "S", "sequence_mut": "D", "comment": "Phosphomimetic mutant that fully rescues climbing defects and significantly improves flight defects, and thorax and wing posture phenotypes in Pink1 mutants. No effect on acyl-CoA dehydrogenase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSA3", "url": "https://www.uniprot.org/uniprotkb/Q9VSA3" }, { "database": "PubMed", "id": "29563254", "url": "https://glygen.org/publication/PubMed/29563254" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VSD7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSD7", "url": "https://www.uniprot.org/uniprotkb/Q9VSD7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 534, "chemical_mass": 59462.0, "gene_names": "ldbr;CG7942;DBR1;Dmel\\CG7942;Lbdr;Ldbr;ldbr", "protein_name": "Lariat debranching enzyme", "disease": [ { "disease_id": "DOID:936", "name": "brain disease", "description": "A central nervous system disease that is located_in the brain.", "url": "https://disease-ontology.org/term/DOID:936", "evidence": [ { "id": "936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:936" } ], "weight": 0.0 } ], "biological_process": [ { "name": "RNA splicing, via transesterification reactions", "id": "GO:0000375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000375", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD7", "url": "https://www.uniprot.org/uniprotkb/Q9VSD7" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD7", "url": "https://www.uniprot.org/uniprotkb/Q9VSD7" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD7", "url": "https://www.uniprot.org/uniprotkb/Q9VSD7" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA lariat debranching enzyme activity", "id": "GO:0008419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008419", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD7", "url": "https://www.uniprot.org/uniprotkb/Q9VSD7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD7", "url": "https://www.uniprot.org/uniprotkb/Q9VSD7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD7", "url": "https://www.uniprot.org/uniprotkb/Q9VSD7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VSJ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 693, "chemical_mass": 80026.0, "gene_names": "Exo70;CG7127;Dmel\\CG7127;Exo70p;Exo70;exo70", "protein_name": "Exocyst complex component 7", "disease": [ { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 } ], "biological_process": [ { "name": "synaptic vesicle targeting", "id": "GO:0016080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016080", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "synaptic assembly at neuromuscular junction", "id": "GO:0051124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051124", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "synaptic vesicle docking", "id": "GO:0016081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016081", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" } ], "cellular_component": [ { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VSJ8-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ8" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VSJ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VSJ8" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VSS1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 611, "chemical_mass": 69298.0, "gene_names": "pix;ABCE1;BEST:GH18088;CG5651;DmCG5651;Dmel\\CG5651;E3-c;Pix;pix", "protein_name": "Protein Pixie", "disease": [ { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, non-stop decay", "id": "GO:0070481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070481", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "translational termination", "id": "GO:0006415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006415", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VSS1-1", "start_pos": "146", "end_pos": "146", "site_lbl": "Pro146", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "Does not affect development. Viable but with reduced body and bristle size; when associated with L-38 or T-77.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" }, { "database": "PubMed", "id": "16291791", "url": "https://glygen.org/publication/PubMed/16291791" } ] } ] }, { "uniprot_canonical_ac": "Q9VSS1-1", "start_pos": "231", "end_pos": "231", "site_lbl": "Gln231", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "L", "comment": "Embryonic lethal.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" }, { "database": "PubMed", "id": "16291791", "url": "https://glygen.org/publication/PubMed/16291791" } ] } ] }, { "uniprot_canonical_ac": "Q9VSS1-1", "start_pos": "38", "end_pos": "38", "site_lbl": "Pro38", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "Larval lethal. Viable but with reduced body and bristle size; when associated with L-146.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" }, { "database": "PubMed", "id": "16291791", "url": "https://glygen.org/publication/PubMed/16291791" } ] } ] }, { "uniprot_canonical_ac": "Q9VSS1-1", "start_pos": "503", "end_pos": "503", "site_lbl": "Glu503", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Constitutively associates with the 40S ribosomal subunit.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" }, { "database": "PubMed", "id": "17392269", "url": "https://glygen.org/publication/PubMed/17392269" } ] } ] }, { "uniprot_canonical_ac": "Q9VSS1-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Ala77", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "T", "comment": "Embryonic lethal. Viable but with reduced body and bristle size; when associated with L-146.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS1", "url": "https://www.uniprot.org/uniprotkb/Q9VSS1" }, { "database": "PubMed", "id": "16291791", "url": "https://glygen.org/publication/PubMed/16291791" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VSS7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSS7", "url": "https://www.uniprot.org/uniprotkb/Q9VSS7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 250, "chemical_mass": 28564.0, "gene_names": "CG5280;Dmel\\CG5280", "protein_name": "UPF0193 protein EVG1 homolog", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VT57-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 454, "chemical_mass": 53682.0, "gene_names": "Cdk8;CDK8;CG10572;Cdk8;DmCdk8;Dmel\\CG10572;cdk8;dCdk8;dTRAP56;p58", "protein_name": "Cyclin-dependent kinase 8", "disease": [ { "disease_id": "DOID:0112221", "name": "developmental and epileptic encephalopathy 87", "description": "A developmental and epileptic encephalopathy characterized by global developmental delay, severely impaired motor and cognitive development, hypotonia, and onset of frequent refractory seizures or infantile spasms between 6 and 15 months of age that has_material_basis_in heterozygous mutation in the CDK19 gene on chromosome 6q21.", "url": "https://disease-ontology.org/term/DOID:0112221", "evidence": [ { "id": "0112221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112221" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat kinase activity", "id": "GO:0008353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008353", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "CKM complex", "id": "GO:1990508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990508", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "sex comb development", "id": "GO:0045498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045498", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" }, { "name": "imaginal disc-derived leg segmentation", "id": "GO:0036011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036011", "evidence": [ { "database": "UniProtKB", "id": "Q9VT57", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VTC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTC4", "url": "https://www.uniprot.org/uniprotkb/Q9VTC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 156, "chemical_mass": 17587.0, "gene_names": "galla-2;CG7949;CIAO2B;Dmel\\CG7949;Galla-2;Galla2;galla-2;galla2", "protein_name": "MIP18 family protein galla-2", "disease": [], "cellular_component": [ { "name": "cytosolic [4Fe-4S] assembly targeting complex", "id": "GO:0097361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097361", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC4", "url": "https://www.uniprot.org/uniprotkb/Q9VTC4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC4", "url": "https://www.uniprot.org/uniprotkb/Q9VTC4" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC4", "url": "https://www.uniprot.org/uniprotkb/Q9VTC4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC4", "url": "https://www.uniprot.org/uniprotkb/Q9VTC4" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC4", "url": "https://www.uniprot.org/uniprotkb/Q9VTC4" } ], "pmid": "" }, { "name": "[4Fe-4S] cluster assembly", "id": "GO:0044572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044572", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC4", "url": "https://www.uniprot.org/uniprotkb/Q9VTC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VTE0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 159, "chemical_mass": 17564.0, "gene_names": "Blos2;BLOS2;Blos2;CG14145;DmBlos2;Dmel\\CG14145;NP_648427;blos2", "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 2", "disease": [ { "disease_id": "DOID:3753", "name": "Hermansky-Pudlak syndrome", "description": "A syndrome characterized by oculocutaneous albinism, bleeding problems due to platelet storage pool defect, visual impairment and lysosomal accumulation of ceroid lipofuscin.", "url": "https://disease-ontology.org/term/DOID:3753", "evidence": [ { "id": "3753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3753" } ], "weight": 0.0 } ], "biological_process": [ { "name": "eye pigment granule organization", "id": "GO:0008057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008057", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" }, { "name": "organelle transport along microtubule", "id": "GO:0072384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072384", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" }, { "name": "autophagosome-lysosome fusion", "id": "GO:0061909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061909", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" }, { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasmic side of lysosomal membrane", "id": "GO:0098574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098574", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" }, { "name": "BORC complex", "id": "GO:0099078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099078", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" }, { "name": "BLOC-1 complex", "id": "GO:0031083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031083", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" }, { "name": "gamma-tubulin complex", "id": "GO:0000930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000930", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE0", "url": "https://www.uniprot.org/uniprotkb/Q9VTE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VTJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 494, "chemical_mass": 57723.0, "gene_names": "Fuca;CG33047;CG6128;DmFuca;Dmel\\CG6128;Fuca_Dm;Fuca;Fuc;a-FUC;alpha-FUC;fuc", "protein_name": "Putative alpha-L-fucosidase", "disease": [ { "disease_id": "DOID:14500", "name": "fucosidosis", "description": "", "url": "https://disease-ontology.org/term/DOID:14500", "evidence": [ { "id": "14500", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14500" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "biological_process": [ { "name": "binding of sperm to zona pellucida", "id": "GO:0007339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007339", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" }, { "name": "glycoside catabolic process", "id": "GO:0016139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016139", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" }, { "name": "fucose metabolic process", "id": "GO:0006004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006004", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" }, { "name": "sperm plasma membrane", "id": "GO:0097524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097524", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" }, { "name": "outer acrosomal membrane", "id": "GO:0002081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002081", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "fucose binding", "id": "GO:0042806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042806", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" }, { "name": "alpha-L-fucosidase activity", "id": "GO:0004560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004560", "evidence": [ { "database": "UniProtKB", "id": "Q9VTJ4", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VTJ4-1", "start_pos": "113", "end_pos": "113", "site_lbl": "Asn113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 113, "start_aa": "Asn", "end_pos": 113, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn113", "evidence": [ { "id": "Q9VTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VTJ4-1", "start_pos": "377", "end_pos": "377", "site_lbl": "Asn377", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 377, "start_aa": "Asn", "end_pos": 377, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn377", "evidence": [ { "id": "Q9VTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VTM0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 167, "chemical_mass": 18963.0, "gene_names": "Pldn;CG14133;Dmel\\CG14133;NP_648494;Pallidin;Pldn;pallidin;pldn", "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 6", "disease": [ { "disease_id": "DOID:0060547", "name": "Hermansky-Pudlak syndrome 9", "description": "A Hermansky-Pudlak syndrome that has_material_basis_in homozygous mutation in the gene encoding palladin (BLOC1S6) on chromosome 15q21.", "url": "https://disease-ontology.org/term/DOID:0060547", "evidence": [ { "id": "0060547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060547" } ], "weight": 0.0 }, { "disease_id": "DOID:2223", "name": "platelet storage pool deficiency", "description": "", "url": "https://disease-ontology.org/term/DOID:2223", "evidence": [ { "id": "2223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2223" } ], "weight": 0.0 }, { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 } ], "biological_process": [ { "name": "eye pigment granule organization", "id": "GO:0008057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008057", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" }, { "name": "synaptic vesicle recycling via endosome", "id": "GO:0036466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036466", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle cycle", "id": "GO:0098693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098693", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" }, { "name": "BLOC-1 complex", "id": "GO:0031083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031083", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" }, { "name": "type I terminal bouton", "id": "GO:0061174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061174", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" }, { "name": "postsynapse of neuromuscular junction", "id": "GO:0098975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098975", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM0", "url": "https://www.uniprot.org/uniprotkb/Q9VTM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VTT9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTT9", "url": "https://www.uniprot.org/uniprotkb/Q9VTT9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 492, "chemical_mass": 55408.0, "gene_names": "DEF8;BEST:GH12489;CG11534;DEF8;Def8;Dmel\\CG11534", "protein_name": "Differentially expressed in FDCP 8 homolog", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VTT9", "url": "https://www.uniprot.org/uniprotkb/Q9VTT9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VTU4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTU4", "url": "https://www.uniprot.org/uniprotkb/Q9VTU4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 539, "chemical_mass": 63223.0, "gene_names": "eIF3l;CG5642;Dmel\\CG5642;eIF3l", "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU4", "url": "https://www.uniprot.org/uniprotkb/Q9VTU4" } ], "pmid": "" }, { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU4", "url": "https://www.uniprot.org/uniprotkb/Q9VTU4" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU4", "url": "https://www.uniprot.org/uniprotkb/Q9VTU4" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU4", "url": "https://www.uniprot.org/uniprotkb/Q9VTU4" } ], "pmid": "" } ], "biological_process": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU4", "url": "https://www.uniprot.org/uniprotkb/Q9VTU4" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU4", "url": "https://www.uniprot.org/uniprotkb/Q9VTU4" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU4", "url": "https://www.uniprot.org/uniprotkb/Q9VTU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VU31-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU31", "url": "https://www.uniprot.org/uniprotkb/Q9VU31" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 265, "chemical_mass": 30279.0, "gene_names": "CG11263;Dmel\\CG11263", "protein_name": "Protein Exd1 homolog", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VU31", "url": "https://www.uniprot.org/uniprotkb/Q9VU31" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q9VU31", "url": "https://www.uniprot.org/uniprotkb/Q9VU31" } ], "pmid": "" } ], "cellular_component": [ { "name": "PET complex", "id": "GO:1990923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990923", "evidence": [ { "database": "UniProtKB", "id": "Q9VU31", "url": "https://www.uniprot.org/uniprotkb/Q9VU31" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "Q9VU31", "url": "https://www.uniprot.org/uniprotkb/Q9VU31" } ], "pmid": "" } ], "biological_process": [ { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "Q9VU31", "url": "https://www.uniprot.org/uniprotkb/Q9VU31" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VU95-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU95", "url": "https://www.uniprot.org/uniprotkb/Q9VU95" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 494, "chemical_mass": 54284.0, "gene_names": "CG8745;Dmel\\CG8745", "protein_name": "Alanine--glyoxylate aminotransferase 2-like", "disease": [], "molecular_function": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "Q9VU95", "url": "https://www.uniprot.org/uniprotkb/Q9VU95" } ], "pmid": "" }, { "name": "ethanolamine-phosphate phospho-lyase activity", "id": "GO:0050459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050459", "evidence": [ { "database": "UniProtKB", "id": "Q9VU95", "url": "https://www.uniprot.org/uniprotkb/Q9VU95" } ], "pmid": "" } ], "biological_process": [ { "name": "response to nicotine", "id": "GO:0035094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035094", "evidence": [ { "database": "UniProtKB", "id": "Q9VU95", "url": "https://www.uniprot.org/uniprotkb/Q9VU95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VUC6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1183, "chemical_mass": 133159.0, "gene_names": "Frl;CG13485;CG32138;CG43986;CG6807;Dmel\\CG32138;Frl;Q9VUC5_DROME;Q9VUC6_DROME;anon-WO0172774.98;frl", "protein_name": "Formin-like protein", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" }, { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" }, { "name": "ommatidial rotation", "id": "GO:0016318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016318", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VUC6-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Thr542", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 542, "start_aa": "Thr", "end_pos": 542, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr542", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VUC6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VUC6" } ] } ] }, { "uniprot_canonical_ac": "Q9VUC6-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Ser225", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC6", "url": "https://www.uniprot.org/uniprotkb/Q9VUC6" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VUC6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VUC6" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VUK8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 765, "chemical_mass": 85192.0, "gene_names": "GlyRS;Aat-gly;Aats-gly;CG6778;Dmel\\CG6778;GARS;GRS;Gars;GlyRS;aaRS(Gly);dGARS1;dGARS;dGars;gars;team", "protein_name": "Glycine--tRNA ligase", "disease": [ { "disease_id": "DOID:0050539", "name": "Charcot-Marie-Tooth disease type 2", "description": "A Charcot-Marie-Tooth disease characterized by abnormalities in the axon of the peripheral nerve cell.", "url": "https://disease-ontology.org/term/DOID:0050539", "evidence": [ { "id": "0050539", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050539" } ], "weight": 0.0 }, { "disease_id": "DOID:0110164", "name": "Charcot-Marie-Tooth disease type 2D", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in mutation in the GARS1 gene.", "url": "https://disease-ontology.org/term/DOID:0110164", "evidence": [ { "id": "0110164", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110164" } ], "weight": 0.0 }, { "disease_id": "DOID:0111203", "name": "autosomal dominant distal hereditary motor neuronopathy 5", "description": "An autosomal dominant distal hereditary motor neuronopathy that is characterized by onset of distal muscle weakness and atrophy predominantly affecting the upper limbs in the first few decades of life and that has_material_basis_in heterozygous mutation in the GARS gene on chromosome 7p14.", "url": "https://disease-ontology.org/term/DOID:0111203", "evidence": [ { "id": "0111203", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111203" } ], "weight": 0.0 }, { "disease_id": "DOID:10595", "name": "Charcot-Marie-Tooth disease", "description": "A neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm.", "url": "https://disease-ontology.org/term/DOID:10595", "evidence": [ { "id": "10595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10595" } ], "weight": 0.0 }, { "disease_id": "DOID:12377", "name": "spinal muscular atrophy", "description": "A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.", "url": "https://disease-ontology.org/term/DOID:12377", "evidence": [ { "id": "12377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12377" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" }, { "name": "glycine-tRNA ligase activity", "id": "GO:0004820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004820", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" } ], "biological_process": [ { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" }, { "name": "mitochondrial glycyl-tRNA aminoacylation", "id": "GO:0070150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070150", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" }, { "name": "glycyl-tRNA aminoacylation", "id": "GO:0006426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006426", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VUK8-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Thr46", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VUK8-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VUK8-1", "start_pos": "320", "end_pos": "320", "site_lbl": "Pro320", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "K", "comment": "When overexpressed in the whole body, leads to motor deficits, progressive neuromuscular junction (NMJ) denervation and pre-synaptic build-up of mutant GlyRS ultimately causing lethality. Similar effects are shown when overexpressed in the mesoderm or neurons. Accumulates at the synapse. When overexpressed in neurons, impairs progressively neuronal functionality and morphology. Toxicity might be mediated by modulation of the plexin-semaphorin signaling. Suppresses accumulation at the synapse, reduced fly viability and defective neuromuscular junction; when associated with 97-A--F-163 DEL.", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" }, { "database": "PubMed", "id": "24807208", "url": "https://glygen.org/publication/PubMed/24807208" }, { "database": "PubMed", "id": "29520219", "url": "https://glygen.org/publication/PubMed/29520219" }, { "database": "PubMed", "id": "25972375", "url": "https://glygen.org/publication/PubMed/25972375" } ] } ] }, { "uniprot_canonical_ac": "Q9VUK8-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Gly326", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "When overexpressed in the whole body or mesoderm, impairs development and reduces longevity. When overexpressed in neurons, impairs progressively neuronal functionality and morphology.", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" }, { "database": "PubMed", "id": "24807208", "url": "https://glygen.org/publication/PubMed/24807208" }, { "database": "PubMed", "id": "25972375", "url": "https://glygen.org/publication/PubMed/25972375" } ] } ] }, { "uniprot_canonical_ac": "Q9VUK8-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Met87", "weight": 0.0, "mutagenesis": [ { "sequence_org": "M", "sequence_mut": "T", "comment": "Results in increased localization to mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" }, { "database": "PubMed", "id": "17529987", "url": "https://glygen.org/publication/PubMed/17529987" } ] } ] }, { "uniprot_canonical_ac": "Q9VUK8-1", "start_pos": "98", "end_pos": "98", "site_lbl": "Pro98", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "Results in neuronal terminal arborization defects and loss of neuroblasts.", "evidence": [ { "database": "UniProtKB", "id": "Q9VUK8", "url": "https://www.uniprot.org/uniprotkb/Q9VUK8" }, { "database": "PubMed", "id": "17529987", "url": "https://glygen.org/publication/PubMed/17529987" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VUL9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUL9", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 503, "chemical_mass": 59160.0, "gene_names": "FucTA;3-FucT;CG6869;Dm alpha1;Dmel\\CG6869;FucTA;anon-EST:Posey285;fucTA", "protein_name": "Core alpha-(1,3)-fucosyltransferase", "disease": [ { "disease_id": "DOID:1508", "name": "candidiasis", "description": "An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.", "url": "https://disease-ontology.org/term/DOID:1508", "evidence": [ { "id": "1508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1508" } ], "weight": 0.0 } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL9", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL9", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9" } ], "pmid": "" }, { "name": "Golgi apparatus N-glycan diversification", "id": "GO:0016258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016258", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL9", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL9", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9" } ], "pmid": "" }, { "name": "Golgi medial cisterna", "id": "GO:0005797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005797", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL9", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9" } ], "pmid": "" } ], "molecular_function": [ { "name": "alpha-(1->3)-fucosyltransferase activity", "id": "GO:0046920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046920", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL9", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9" } ], "pmid": "" }, { "name": "glycoprotein 3-alpha-L-fucosyltransferase activity", "id": "GO:0018392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018392", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL9", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VUL9-1", "start_pos": "262", "end_pos": "262", "site_lbl": "Asn262", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 262, "start_aa": "Asn", "end_pos": 262, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn262", "evidence": [ { "id": "Q9VUL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VUL9-1", "start_pos": "295", "end_pos": "295", "site_lbl": "Asn295", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 295, "start_aa": "Asn", "end_pos": 295, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn295", "evidence": [ { "id": "Q9VUL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VUL9-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Asn299", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 299, "start_aa": "Asn", "end_pos": 299, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn299", "evidence": [ { "id": "Q9VUL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUL9#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VUT6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 590, "chemical_mass": 68100.0, "gene_names": "Pgant8;CG7297;Dmel\\CG7297;Pgant8;pgant8", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 8", "disease": [ { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "pmid": "" } ], "biological_process": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "Q9VUT6", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VUT6-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Asn241", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 241, "start_aa": "Asn", "end_pos": 241, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn241", "evidence": [ { "id": "Q9VUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VUT6-1", "start_pos": "77", "end_pos": "77", "site_lbl": "Asn77", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 77, "start_aa": "Asn", "end_pos": 77, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn77", "evidence": [ { "id": "Q9VUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUT6#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VV87-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 316, "chemical_mass": 36829.0, "gene_names": "Baldspot;Baldspot;CG 3971;CG3971;Dmel\\CG3971;ELOVL6;Elovl6;NEST:bs18f10;NEST:bs18g10;baldspot;blp;l(3)01895;l(3)02281;l(3)04106;l(3)neo21;l(3)neo22;noa", "protein_name": "Very long chain fatty acid elongase 6", "disease": [], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" }, { "name": "fatty acid elongation", "id": "GO:0030497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030497", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" }, { "name": "fatty acid elongation, monounsaturated fatty acid", "id": "GO:0034625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034625", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" }, { "name": "fatty acid elongation, polyunsaturated fatty acid", "id": "GO:0034626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034626", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" }, { "name": "long-chain fatty acid biosynthetic process", "id": "GO:0042759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042759", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" }, { "name": "fatty acid elongation, saturated fatty acid", "id": "GO:0019367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019367", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acid elongase activity", "id": "GO:0009922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009922", "evidence": [ { "database": "UniProtKB", "id": "Q9VV87", "url": "https://www.uniprot.org/uniprotkb/Q9VV87" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VV87-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Asn11", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 11, "start_aa": "Asn", "end_pos": 11, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn11", "evidence": [ { "id": "Q9VV87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV87#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VV87-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Asn242", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 242, "start_aa": "Asn", "end_pos": 242, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn242", "evidence": [ { "id": "Q9VV87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV87#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VVB4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVB4", "url": "https://www.uniprot.org/uniprotkb/Q9VVB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 555, "chemical_mass": 63013.0, "gene_names": "CG9951;Dmel\\CG9951", "protein_name": "Coiled-coil domain-containing protein 22 homolog", "disease": [ { "disease_id": "DOID:0060572", "name": "Ritscher-Schinzel syndrome 2", "description": "A Ritscher-Schinzel syndrome that has_material_basis_in mutation in the CCDC22 gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0060572", "evidence": [ { "id": "0060572", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060572" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "Q9VVB4", "url": "https://www.uniprot.org/uniprotkb/Q9VVB4" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": "GO:2000060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000060", "evidence": [ { "database": "UniProtKB", "id": "Q9VVB4", "url": "https://www.uniprot.org/uniprotkb/Q9VVB4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VVN4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 846, "chemical_mass": 96119.0, "gene_names": "mus304;ATRIP;CG7347;Dmel\\CG7347;Mus304;anon-WO0140519.82;atrip;mus(3)304;mus-304;mus304", "protein_name": "ATR-interacting protein mus304", "disease": [], "biological_process": [ { "name": "female meiosis chromosome segregation", "id": "GO:0016321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016321", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "female meiotic nuclear division", "id": "GO:0007143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007143", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "response to radiation", "id": "GO:0009314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009314", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "regulation of syncytial blastoderm mitotic cell cycle", "id": "GO:0007348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007348", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "imaginal disc development", "id": "GO:0007444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007444", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVN4-1", "start_pos": "600", "end_pos": "600", "site_lbl": "Gly600", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "In mus304-4; induces abnormal bristle morphology, decreased meiotic recombination and arrested embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" }, { "database": "PubMed", "id": "10733527", "url": "https://glygen.org/publication/PubMed/10733527" } ] } ] }, { "uniprot_canonical_ac": "Q9VVN4-1", "start_pos": "695", "end_pos": "695", "site_lbl": "Val695", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "E", "comment": "In mus304-3; induces abnormal bristle morphology, decreased meiotic recombination and arrested embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" }, { "database": "PubMed", "id": "10733527", "url": "https://glygen.org/publication/PubMed/10733527" } ] } ] }, { "uniprot_canonical_ac": "Q9VVN4-1", "start_pos": "718", "end_pos": "718", "site_lbl": "Gly718", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In mus304-6; induces abnormal bristle morphology, decreased meiotic recombination and arrested embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "Q9VVN4", "url": "https://www.uniprot.org/uniprotkb/Q9VVN4" }, { "database": "PubMed", "id": "10733527", "url": "https://glygen.org/publication/PubMed/10733527" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VVR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 539, "chemical_mass": 59142.0, "gene_names": "bora;CG6897;Dmel\\CG6897;bora", "protein_name": "Protein aurora borealis", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "pmid": "" }, { "name": "activation of protein kinase activity", "id": "GO:0032147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032147", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "pmid": "" }, { "name": "asymmetric protein localization involved in cell fate determination", "id": "GO:0045167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045167", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVR2-1", "start_pos": "383", "end_pos": "383", "site_lbl": "Ser383", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR2", "url": "https://www.uniprot.org/uniprotkb/Q9VVR2" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VVR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VVR2" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VVR9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVR9", "url": "https://www.uniprot.org/uniprotkb/Q9VVR9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 524, "chemical_mass": 60598.0, "gene_names": "Cyp12c1;12c1;CG4120;Cyp12C1;Cyp12c1;Cyp12c;Dmel\\CG4120;Dmel_CG4120;cyp12c1", "protein_name": "Probable cytochrome P450 12c1, mitochondrial", "disease": [ { "disease_id": "DOID:0050860", "name": "colorectal adenoma", "description": "An intestinal benign neoplasm that has_material_basis_in epithelial tissue of glandular origin and is located_in colon and located_in rectum.", "url": "https://disease-ontology.org/term/DOID:0050860", "evidence": [ { "id": "0050860", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050860" } ], "weight": 0.0 }, { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0061136", "name": "infantile hypercalcemia 1", "description": "A hypercalcemia that has_material_basis_in homozygous or compound heterozygous mutation in the CYP24A1 gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0061136", "evidence": [ { "id": "0061136", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061136" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 }, { "disease_id": "DOID:0080815", "name": "childhood-onset asthma", "description": "A chronic asthma that is characterized by first presentation in early childhood.", "url": "https://disease-ontology.org/term/DOID:0080815", "evidence": [ { "id": "0080815", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080815" } ], "weight": 0.0 }, { "disease_id": "DOID:0080886", "name": "vitamin D-dependent rickets type 1A", "description": "A vitamin D-dependent rickets that is characterized by abnormally low levels of calcitriol and that has_material_basis_in mutation in the gene encoding 25-hydroxyvitamin D3-1-alpha-hydroxylase (CYP27B1) on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0080886", "evidence": [ { "id": "0080886", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080886" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10609", "name": "rickets", "description": "A bone remodeling disease that has_material_basis_in impaired mineralization or calcification of bones before epiphyseal closure due to deficiency or impaired metabolism of vitamin D, phosphorus or calcium which results_in softening and deformity located_in bone.", "url": "https://disease-ontology.org/term/DOID:10609", "evidence": [ { "id": "10609", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10609" } ], "weight": 0.0 }, { "disease_id": "DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy.", "url": "https://disease-ontology.org/term/DOID:11714", "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1993", "name": "rectum cancer", "description": "A colorectal cancer that is located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:1993", "evidence": [ { "id": "1993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1993" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:2527", "name": "nephrosis", "description": "A proteinuria that is characterized by the leaking of blood protein into the urine, swelling or edema, and degenerative lesions without inflammation.", "url": "https://disease-ontology.org/term/DOID:2527", "evidence": [ { "id": "2527", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2527" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 }, { "disease_id": "DOID:3713", "name": "ovary adenocarcinoma", "description": "An ovarian carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3713", "evidence": [ { "id": "3713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3713" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3905", "name": "lung carcinoma", "description": "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.", "url": "https://disease-ontology.org/term/DOID:3905", "evidence": [ { "id": "3905", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3905" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:4810", "name": "cerebrotendinous xanthomatosis", "description": "A xanthomatosis that is characterized by a deficiency in the production of the bile acid, chenodeoxycholic acid that has_material_basis_in homozygous or compound heterozygous mutation in the CYP27A1 gene, which encodes sterol 27-hydroxylase, on chromosome 2q35.", "url": "https://disease-ontology.org/term/DOID:4810", "evidence": [ { "id": "4810", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4810" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:5041", "name": "esophageal cancer", "description": "A gastrointestinal system cancer that is located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:5041", "evidence": [ { "id": "5041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5041" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:893", "name": "Wilson disease", "description": "A metal metabolism disease that is characterized by excess copper stored in various body tissues, particularly the liver, brain, and corneas of the eyes.", "url": "https://disease-ontology.org/term/DOID:893", "evidence": [ { "id": "893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:893" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR9", "url": "https://www.uniprot.org/uniprotkb/Q9VVR9" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR9", "url": "https://www.uniprot.org/uniprotkb/Q9VVR9" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR9", "url": "https://www.uniprot.org/uniprotkb/Q9VVR9" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR9", "url": "https://www.uniprot.org/uniprotkb/Q9VVR9" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR9", "url": "https://www.uniprot.org/uniprotkb/Q9VVR9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VVR9", "url": "https://www.uniprot.org/uniprotkb/Q9VVR9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VW15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2226, "chemical_mass": 246266.0, "gene_names": "ash1;ASH-1;ASH1;Ash 1;Ash1;Ash;CG8887;Dmel\\CG8887;KMT2H;ash-1;ash1;ash;dash;l(3)76BDb;l(3)SG29a", "protein_name": "Histone-lysine N-methyltransferase ash1", "disease": [ { "disease_id": "DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.", "url": "https://disease-ontology.org/term/DOID:0060037", "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080231", "name": "autosomal dominant intellectual developmental disorder 52", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the ASH1L gene on chromosome 1q22.", "url": "https://disease-ontology.org/term/DOID:0080231", "evidence": [ { "id": "0080231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080231" } ], "weight": 0.0 }, { "disease_id": "DOID:1240", "name": "leukemia", "description": "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.", "url": "https://disease-ontology.org/term/DOID:1240", "evidence": [ { "id": "1240", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1240" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "histone H3K4 methyltransferase activity", "id": "GO:0042800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042800", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "histone H3K36 methyltransferase activity", "id": "GO:0046975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046975", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "histone acetyltransferase binding", "id": "GO:0035035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035035", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "histone H3K36 dimethyltransferase activity", "id": "GO:0140954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140954", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "histone H3K4 trimethyltransferase activity", "id": "GO:0140999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140999", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "histone methyltransferase complex", "id": "GO:0035097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "egg-laying behavior", "id": "GO:0018991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018991", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" }, { "name": "transposable element silencing by heterochromatin formation", "id": "GO:0141005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141005", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "1113", "end_pos": "1113", "site_lbl": "Thr1113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1113, "start_aa": "Thr", "end_pos": 1113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1113", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "2123", "end_pos": "2123", "site_lbl": "Thr2123", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2123, "start_aa": "Thr", "end_pos": 2123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2123", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "543", "end_pos": "543", "site_lbl": "Thr543", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 543, "start_aa": "Thr", "end_pos": 543, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr543", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Ser135", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VW15", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VW15" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Ser136", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VW15", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VW15" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "138", "end_pos": "138", "site_lbl": "Ser138", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VW15", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VW15" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VW15", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VW15" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "201", "end_pos": "201", "site_lbl": "Thr201", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VW15", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VW15" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "740", "end_pos": "740", "site_lbl": "Ser740", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VW15", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VW15" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "831", "end_pos": "831", "site_lbl": "Ser831", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VW15", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VW15" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "977", "end_pos": "977", "site_lbl": "Ser977", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VW15", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VW15" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "1284", "end_pos": "1284", "site_lbl": "Glu1284", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "In ash1-21; induces lethality between prepupal and late pupal stages.", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "8725238", "url": "https://glygen.org/publication/PubMed/8725238" } ] } ] }, { "uniprot_canonical_ac": "Q9VW15-1", "start_pos": "1473", "end_pos": "1473", "site_lbl": "Asn1473", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "I", "comment": "In ash1-10; induces lethality between prepupal and late pupal stages.", "evidence": [ { "database": "UniProtKB", "id": "Q9VW15", "url": "https://www.uniprot.org/uniprotkb/Q9VW15" }, { "database": "PubMed", "id": "8725238", "url": "https://glygen.org/publication/PubMed/8725238" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VW43-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW43", "url": "https://www.uniprot.org/uniprotkb/Q9VW43" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 504, "chemical_mass": 57720.0, "gene_names": "Cyp305a1;305a1;AAF49108.1;CG8733;CYP305A1-Dm;CYP305A1;Cyp305A1;Cyp305a1;Dmel\\CG8733", "protein_name": "Probable cytochrome P450 305a1", "disease": [ { "disease_id": "DOID:0050073", "name": "invasive aspergillosis", "description": "An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage.", "url": "https://disease-ontology.org/term/DOID:0050073", "evidence": [ { "id": "0050073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050073" } ], "weight": 0.0 }, { "disease_id": "DOID:0050083", "name": "Keshan disease", "description": "A nutritional deficiency that is disease characterized by a cardiomyopathy secondary to selenium deficiency.", "url": "https://disease-ontology.org/term/DOID:0050083", "evidence": [ { "id": "0050083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050083" } ], "weight": 0.0 }, { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0050855", "name": "renal fibrosis", "description": "A kidney disease that is characterized by progressive detrimental connective tissue deposition of the kidney parenchyma leading to deterioration of renal function.", "url": "https://disease-ontology.org/term/DOID:0050855", "evidence": [ { "id": "0050855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050855" } ], "weight": 0.0 }, { "disease_id": "DOID:0050868", "name": "hepatocellular adenoma", "description": "A liver benign neoplasm that is located_in liver cells and that is composed_of epithelial tissue in which tumor cells form glands or glandlike structures.", "url": "https://disease-ontology.org/term/DOID:0050868", "evidence": [ { "id": "0050868", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050868" } ], "weight": 0.0 }, { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080665", "name": "warfarin resistance", "description": "An inherited metabolic disorder that is characterized by a high tolerance for the drug warfarin.", "url": "https://disease-ontology.org/term/DOID:0080665", "evidence": [ { "id": "0080665", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080665" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:1073", "name": "renal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1073", "evidence": [ { "id": "1073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1073" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain.", "url": "https://disease-ontology.org/term/DOID:10923", "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:13922", "name": "eosinophilic esophagitis", "description": "An esophagitis characterized by inflammation involving eosinophils located_in esophagus.", "url": "https://disease-ontology.org/term/DOID:13922", "evidence": [ { "id": "13922", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13922" } ], "weight": 0.0 }, { "disease_id": "DOID:14067", "name": "Plasmodium falciparum malaria", "description": "A malaria described as a severe form of the disease caused by a parasite Plasmodium falciparum, which is marked by irrregular recurrence of paroxysms and prolonged or continuous fever.", "url": "https://disease-ontology.org/term/DOID:14067", "evidence": [ { "id": "14067", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14067" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2044", "name": "drug-induced hepatitis", "description": "", "url": "https://disease-ontology.org/term/DOID:2044", "evidence": [ { "id": "2044", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2044" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:4661", "name": "multiple chemical sensitivity", "description": "A syndrome that is an adverse physical reaction to low levels of many common chemicals.", "url": "https://disease-ontology.org/term/DOID:4661", "evidence": [ { "id": "4661", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4661" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:5520", "name": "head and neck squamous cell carcinoma", "description": "A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck.", "url": "https://disease-ontology.org/term/DOID:5520", "evidence": [ { "id": "5520", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5520" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:750", "name": "peptic ulcer disease", "description": "", "url": "https://disease-ontology.org/term/DOID:750", "evidence": [ { "id": "750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:750" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9828", "name": "neonatal abstinence syndrome", "description": "A withdrawal disorder that is characterized by a group of problems that occur in a newborn who was exposed to addictive illegal or prescription drugs while in the mother's womb or postnatally following the discontinuance of drug treatment.", "url": "https://disease-ontology.org/term/DOID:9828", "evidence": [ { "id": "9828", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9828" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9974", "name": "drug dependence", "description": "A substance dependence that involves the continued use of drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9974", "evidence": [ { "id": "9974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9974" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 }, { "disease_id": "DOID:9993", "name": "hypoglycemia", "description": "A glucose metabolism disease that is characterized by abnormally low levels of blood glucose.", "url": "https://disease-ontology.org/term/DOID:9993", "evidence": [ { "id": "9993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9993" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VW43", "url": "https://www.uniprot.org/uniprotkb/Q9VW43" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VW43", "url": "https://www.uniprot.org/uniprotkb/Q9VW43" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VW43", "url": "https://www.uniprot.org/uniprotkb/Q9VW43" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VW43", "url": "https://www.uniprot.org/uniprotkb/Q9VW43" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VW43", "url": "https://www.uniprot.org/uniprotkb/Q9VW43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VW71-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4699, "chemical_mass": 523781.0, "gene_names": "kug;CG7749;CT23445;Cad76E;DCad76E;Dmel\\CG7749;Dmel_CG7749;Fat-like;Fat2;Ftl;Kug;RE-A;fat2;fat;ft2;ftl;kug", "protein_name": "Fat-like cadherin-related tumor suppressor homolog", "disease": [ { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0080287", "name": "spinocerebellar ataxia 45", "description": "An autosomal dominant cerebellar ataxia that has_material_basis_in heterozygous mutation in the FAT2 gene on chromosome 5q33.", "url": "https://disease-ontology.org/term/DOID:0080287", "evidence": [ { "id": "0080287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080287" } ], "weight": 0.0 }, { "disease_id": "DOID:11727", "name": "facioscapulohumeral muscular dystrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:11727", "evidence": [ { "id": "11727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11727" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "hindgut morphogenesis", "id": "GO:0007442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007442", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "establishment of planar polarity of follicular epithelium", "id": "GO:0042247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042247", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "establishment or maintenance of actin cytoskeleton polarity", "id": "GO:0030950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030950", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "salivary gland development", "id": "GO:0007431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007431", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "positive regulation of innate immune response", "id": "GO:0045089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045089", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "protein localization to cell leading edge", "id": "GO:1902463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902463", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "foregut morphogenesis", "id": "GO:0007440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007440", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "growth of a germarium-derived egg chamber", "id": "GO:0007295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007295", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "centripetally migrating follicle cell migration", "id": "GO:0060269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060269", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "developmental growth", "id": "GO:0048589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048589", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "digestive tract development", "id": "GO:0048565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048565", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "establishment of planar polarity", "id": "GO:0001736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001736", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "tube morphogenesis", "id": "GO:0035239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035239", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "regulation of plasma membrane bounded cell projection organization", "id": "GO:0120035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120035", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "follicle cell of egg chamber migration", "id": "GO:0007297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007297", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "basal plasma membrane", "id": "GO:0009925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009925", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "cell trailing edge", "id": "GO:0031254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031254", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "actin-based cell projection", "id": "GO:0098858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098858", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "Q9VW71", "url": "https://www.uniprot.org/uniprotkb/Q9VW71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "1109", "end_pos": "1109", "site_lbl": "Asn1109", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1109, "start_aa": "Asn", "end_pos": 1109, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1109", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "1201", "end_pos": "1201", "site_lbl": "Asn1201", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1201, "start_aa": "Asn", "end_pos": 1201, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1201", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "1315", "end_pos": "1315", "site_lbl": "Asn1315", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1315, "start_aa": "Asn", "end_pos": 1315, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1315", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "1442", "end_pos": "1442", "site_lbl": "Asn1442", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1442, "start_aa": "Asn", "end_pos": 1442, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1442", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "1476", "end_pos": "1476", "site_lbl": "Asn1476", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1476, "start_aa": "Asn", "end_pos": 1476, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1476", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "1514", "end_pos": "1514", "site_lbl": "Asn1514", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1514, "start_aa": "Asn", "end_pos": 1514, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1514", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Asn159", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 159, "start_aa": "Asn", "end_pos": 159, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn159", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "367", "end_pos": "367", "site_lbl": "Asn367", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 367, "start_aa": "Asn", "end_pos": 367, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn367", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "530", "end_pos": "530", "site_lbl": "Thr530", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 530, "start_aa": "Thr", "end_pos": 530, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr530", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VW71", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VW71" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Asn68", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 68, "start_aa": "Asn", "end_pos": 68, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn68", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "782", "end_pos": "782", "site_lbl": "Asn782", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 782, "start_aa": "Asn", "end_pos": 782, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn782", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "846", "end_pos": "846", "site_lbl": "Asn846", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 846, "start_aa": "Asn", "end_pos": 846, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn846", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VW71-1", "start_pos": "926", "end_pos": "926", "site_lbl": "Asn926", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 926, "start_aa": "Asn", "end_pos": 926, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn926", "evidence": [ { "id": "Q9VW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW71#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWA8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 262, "chemical_mass": 29530.0, "gene_names": "FRG1;CG6480;DmFRG1;Dmel\\CG6480;FRG1;dFRG1", "protein_name": "Protein FRG1 homolog", "disease": [ { "disease_id": "DOID:11727", "name": "facioscapulohumeral muscular dystrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:11727", "evidence": [ { "id": "11727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11727" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" }, { "name": "striated muscle dense body", "id": "GO:0055120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055120", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" } ], "biological_process": [ { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" }, { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA8", "url": "https://www.uniprot.org/uniprotkb/Q9VWA8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWE0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1282, "chemical_mass": 142361.0, "gene_names": "dome;142932_at;CG14226;CT33841;DOME;Dmel\\CG14226;Domeless;Dome;Dom;anon-18DEb;domeMESO;dome;l(1)G0217;l(1)G0218;l(1)G0264;l(1)G0282;l(1)G0321;l(1)G0367;l(1)G0405;l(1)G0441;l(1)G0468;mom;vsp", "protein_name": "Cytokine receptor", "disease": [ { "disease_id": "DOID:934", "name": "viral infectious disease", "description": "A disease by infectious agent that results in infection, has_material_basis_in Viruses.", "url": "https://disease-ontology.org/term/DOID:934", "evidence": [ { "id": "934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:934" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "STAT family protein binding", "id": "GO:0097677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097677", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "SOCS family protein binding", "id": "GO:0097678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097678", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" } ], "biological_process": [ { "name": "hindgut morphogenesis", "id": "GO:0007442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007442", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "tissue regeneration", "id": "GO:0042246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042246", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "locomotor rhythm", "id": "GO:0045475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045475", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "determination of digestive tract left/right asymmetry", "id": "GO:0071907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071907", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "blastoderm segmentation", "id": "GO:0007350", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007350", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "wing disc morphogenesis", "id": "GO:0007472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007472", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" }, { "name": "apicolateral plasma membrane", "id": "GO:0016327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016327", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Asn114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 114, "start_aa": "Asn", "end_pos": 114, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn114", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "143", "end_pos": "143", "site_lbl": "Asn143", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 143, "start_aa": "Asn", "end_pos": 143, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn143", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Asn156", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 156, "start_aa": "Asn", "end_pos": 156, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn156", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "184", "end_pos": "184", "site_lbl": "Asn184", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 184, "start_aa": "Asn", "end_pos": 184, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn184", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "230", "end_pos": "230", "site_lbl": "Asn230", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 230, "start_aa": "Asn", "end_pos": 230, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn230", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Asn235", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 235, "start_aa": "Asn", "end_pos": 235, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn235", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "264", "end_pos": "264", "site_lbl": "Thr264", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 264, "start_aa": "Thr", "end_pos": 264, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr264", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Asn278", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 278, "start_aa": "Asn", "end_pos": 278, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn278", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "298", "end_pos": "298", "site_lbl": "Asn298", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 298, "start_aa": "Asn", "end_pos": 298, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn298", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "310", "end_pos": "310", "site_lbl": "Asn310", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 310, "start_aa": "Asn", "end_pos": 310, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn310", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "376", "end_pos": "376", "site_lbl": "Asn376", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 376, "start_aa": "Asn", "end_pos": 376, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn376", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Asn448", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 448, "start_aa": "Asn", "end_pos": 448, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn448", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Asn44", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 44, "start_aa": "Asn", "end_pos": 44, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn44", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "466", "end_pos": "466", "site_lbl": "Asn466", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 466, "start_aa": "Asn", "end_pos": 466, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn466", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "568", "end_pos": "568", "site_lbl": "Asn568", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 568, "start_aa": "Asn", "end_pos": 568, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn568", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "581", "end_pos": "581", "site_lbl": "Asn581", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 581, "start_aa": "Asn", "end_pos": 581, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn581", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "626", "end_pos": "626", "site_lbl": "Asn626", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 626, "start_aa": "Asn", "end_pos": 626, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn626", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "676", "end_pos": "676", "site_lbl": "Asn676", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 676, "start_aa": "Asn", "end_pos": 676, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn676", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "703", "end_pos": "703", "site_lbl": "Asn703", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 703, "start_aa": "Asn", "end_pos": 703, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn703", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "777", "end_pos": "777", "site_lbl": "Asn777", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 777, "start_aa": "Asn", "end_pos": 777, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn777", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "790", "end_pos": "790", "site_lbl": "Asn790", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 790, "start_aa": "Asn", "end_pos": 790, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn790", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "862", "end_pos": "862", "site_lbl": "Asn862", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 862, "start_aa": "Asn", "end_pos": 862, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn862", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "86", "end_pos": "86", "site_lbl": "Asn86", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 86, "start_aa": "Asn", "end_pos": 86, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn86", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Asn87", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 87, "start_aa": "Asn", "end_pos": 87, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn87", "evidence": [ { "id": "Q9VWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE0-1", "start_pos": "976", "end_pos": "976", "site_lbl": "Ser976", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE0", "url": "https://www.uniprot.org/uniprotkb/Q9VWE0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE0" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWE6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2111, "chemical_mass": 235187.0, "gene_names": "Elys;CG14215;Dmel\\CG14215;Dmel_CG14215;ELYS;Elys;dElys;elys", "protein_name": "Protein ELYS homolog", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1318", "end_pos": "1318", "site_lbl": "Thr1318", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1318, "start_aa": "Thr", "end_pos": 1318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1318", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VWE6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "2032", "end_pos": "2032", "site_lbl": "Thr2032", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2032, "start_aa": "Thr", "end_pos": 2032, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2032", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1274", "end_pos": "1274", "site_lbl": "Ser1274", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1522", "end_pos": "1522", "site_lbl": "Ser1522", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1525", "end_pos": "1525", "site_lbl": "Ser1525", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1551", "end_pos": "1551", "site_lbl": "Ser1551", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1692", "end_pos": "1692", "site_lbl": "Ser1692", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1695", "end_pos": "1695", "site_lbl": "Thr1695", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1831", "end_pos": "1831", "site_lbl": "Ser1831", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1834", "end_pos": "1834", "site_lbl": "Ser1834", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1840", "end_pos": "1840", "site_lbl": "Ser1840", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1863", "end_pos": "1863", "site_lbl": "Ser1863", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1870", "end_pos": "1870", "site_lbl": "Ser1870", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1880", "end_pos": "1880", "site_lbl": "Ser1880", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1886", "end_pos": "1886", "site_lbl": "Ser1886", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1888", "end_pos": "1888", "site_lbl": "Thr1888", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1934", "end_pos": "1934", "site_lbl": "Ser1934", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1939", "end_pos": "1939", "site_lbl": "Ser1939", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1950", "end_pos": "1950", "site_lbl": "Ser1950", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1953", "end_pos": "1953", "site_lbl": "Ser1953", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1956", "end_pos": "1956", "site_lbl": "Thr1956", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1957", "end_pos": "1957", "site_lbl": "Ser1957", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1958", "end_pos": "1958", "site_lbl": "Ser1958", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1962", "end_pos": "1962", "site_lbl": "Thr1962", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1975", "end_pos": "1975", "site_lbl": "Ser1975", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "1982", "end_pos": "1982", "site_lbl": "Ser1982", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Ser200", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "2025", "end_pos": "2025", "site_lbl": "Ser2025", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "2062", "end_pos": "2062", "site_lbl": "Ser2062", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "2065", "end_pos": "2065", "site_lbl": "Ser2065", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] }, { "uniprot_canonical_ac": "Q9VWE6-1", "start_pos": "2068", "end_pos": "2068", "site_lbl": "Ser2068", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE6", "url": "https://www.uniprot.org/uniprotkb/Q9VWE6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VWE6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWE6" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWF4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 387, "chemical_mass": 43742.0, "gene_names": "MKP-4;CG14211;DMKP-4;Dmel\\CG14211;MAPK;MKP-4;Mkp4", "protein_name": "Dual specificity protein phosphatase MPK-4", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of MAPK cascade", "id": "GO:0043409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043409", "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWF4-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Cys126", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes phosphatase activity. Loss of bsk/JNK binding. Reduced nuclear localization.", "evidence": [ { "database": "UniProtKB", "id": "Q9VWF4", "url": "https://www.uniprot.org/uniprotkb/Q9VWF4" }, { "database": "PubMed", "id": "18456458", "url": "https://glygen.org/publication/PubMed/18456458" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWH4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 377, "chemical_mass": 40844.0, "gene_names": "Idh3a;CG12233;Dmel\\CG12233;IDH3A;Idh3a;dIDH3a;idh3a;l (1) G0156;l(1)G0156;lethal (1) G0156", "protein_name": "Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "disease": [ { "disease_id": "DOID:0050709", "name": "early infantile epileptic encephalopathy", "description": "A neonatal period electroclinical syndrome that is characterized by tonic spasms and partial seizures.", "url": "https://disease-ontology.org/term/DOID:0050709", "evidence": [ { "id": "0050709", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050709" } ], "weight": 0.0 }, { "disease_id": "DOID:0112147", "name": "retinitis pigmentosa 90", "description": "A retinitis pigmentosa characterized by onset in the first decade of life of night blindness that has_material_basis_in homozygous or compound heterozygous mutation in the IDH3A gene on chromosome 15q25.1.", "url": "https://disease-ontology.org/term/DOID:0112147", "evidence": [ { "id": "0112147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112147" } ], "weight": 0.0 }, { "disease_id": "DOID:439", "name": "neuromuscular junction disease", "description": "A neuromuscular disease that is characterized by the disfunction of conduction through the neuromuscular junction.", "url": "https://disease-ontology.org/term/DOID:439", "evidence": [ { "id": "439", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:439" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase (NAD+) activity", "id": "GO:0004449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004449", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase complex (NAD+)", "id": "GO:0045242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045242", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "pmid": "" }, { "name": "isocitrate metabolic process", "id": "GO:0006102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006102", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH4", "url": "https://www.uniprot.org/uniprotkb/Q9VWH4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWH4-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 27, "start_aa": "Thr", "end_pos": 27, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr27", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWN4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1150, "chemical_mass": 128975.0, "gene_names": "Flacc;CG7358;Dmel\\CG7358;Flacc;Xio;flacc;xio", "protein_name": "Fl(2)d-associated complex component", "disease": [], "biological_process": [ { "name": "sex determination", "id": "GO:0007530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007530", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" }, { "name": "mRNA modification", "id": "GO:0016556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016556", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWN4", "url": "https://www.uniprot.org/uniprotkb/Q9VWN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWN4-1", "start_pos": "547", "end_pos": "547", "site_lbl": "Thr547", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 547, "start_aa": "Thr", "end_pos": 547, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr547", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWR2", "url": "https://www.uniprot.org/uniprotkb/Q9VWR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 490, "chemical_mass": 55713.0, "gene_names": "Cyp308a1;308a1;CG6585;Cyp308a1;Dmel\\CG6585", "protein_name": "Probable cytochrome P450 308a1", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VWR2", "url": "https://www.uniprot.org/uniprotkb/Q9VWR2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VWR2", "url": "https://www.uniprot.org/uniprotkb/Q9VWR2" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VWR2", "url": "https://www.uniprot.org/uniprotkb/Q9VWR2" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VWR2", "url": "https://www.uniprot.org/uniprotkb/Q9VWR2" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VWR2", "url": "https://www.uniprot.org/uniprotkb/Q9VWR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWR8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWR8", "url": "https://www.uniprot.org/uniprotkb/Q9VWR8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 872, "chemical_mass": 101097.0, "gene_names": "CG6659;Dmel\\CG6659", "protein_name": "C-mannosyltransferase dpy-19 homolog", "disease": [ { "disease_id": "DOID:0111156", "name": "spermatogenic failure 9", "description": "A male infertility characterized by round-headed spermatozoa lacking an acrosome and that has_material_basis_in autosomal recessive inheritance in a mutation in the DPY19L2 gene on chromosome 12q14.", "url": "https://disease-ontology.org/term/DOID:0111156", "evidence": [ { "id": "0111156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111156" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VWR8", "url": "https://www.uniprot.org/uniprotkb/Q9VWR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "Q9VWR8", "url": "https://www.uniprot.org/uniprotkb/Q9VWR8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein C-linked glycosylation", "id": "GO:0018103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018103", "evidence": [ { "database": "UniProtKB", "id": "Q9VWR8", "url": "https://www.uniprot.org/uniprotkb/Q9VWR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWR8-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Thr666", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 666, "start_aa": "Thr", "end_pos": 666, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr666", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWS4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 343, "chemical_mass": 37829.0, "gene_names": "wgn;CG6531;Dmel\\CG6531;Dmel_CG6531;TNFR;Vader;Wengen;Wgn;Wng;vader;wgn", "protein_name": "Tumor necrosis factor receptor superfamily member wgn", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" }, { "name": "positive regulation of programmed cell death", "id": "GO:0043068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043068", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" }, { "name": "photoreceptor cell axon guidance", "id": "GO:0072499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072499", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" }, { "name": "negative regulation of neuromuscular synaptic transmission", "id": "GO:1900074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900074", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" }, { "name": "positive regulation of neuron remodeling", "id": "GO:1904801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904801", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" } ], "molecular_function": [ { "name": "tumor necrosis factor receptor activity", "id": "GO:0005031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005031", "evidence": [ { "database": "UniProtKB", "id": "Q9VWS4", "url": "https://www.uniprot.org/uniprotkb/Q9VWS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VWW0-3", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 331, "chemical_mass": 34931.0, "gene_names": "CrebB;CG6103;CRE-BP;CREB-B;CREB-b;CREB2-b;CREB2a;CREB2b;CREB2;CREB;Creb B 17A;Creb-B;Creb17A;Creb2-b;Creb2.b;Creb2b;Creb2;CrebB-17A;CrebB-17B;CrebB17-A;CrebB;Creb;DM9;Dmel\\CG6103;FBgn0014467;S162;creb2;crebB;dCREB-2a;dCREB-2;dCREB-B;dCREB2-a;dCREB2-b;dCREB2a;dCREB2b;dCREB2;dCREB;dCbz;dCreb2-b;dCreb2b;dCreb2;dCrebB2;dcreb2-b;l(1)17Af", "protein_name": "Cyclic AMP response element-binding protein B", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0060001", "name": "withdrawal disorder", "description": "A substance-related disorder that occurs upon the abrupt discontinuation/separation or a decrease in dosage of the intake of medications, recreational drugs, and alcohol.", "url": "https://disease-ontology.org/term/DOID:0060001", "evidence": [ { "id": "0060001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060001" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10914", "name": "amnestic disorder", "description": "A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information.", "url": "https://disease-ontology.org/term/DOID:10914", "evidence": [ { "id": "10914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10914" } ], "weight": 0.0 }, { "disease_id": "DOID:10933", "name": "obsessive-compulsive disorder", "description": "An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions).", "url": "https://disease-ontology.org/term/DOID:10933", "evidence": [ { "id": "10933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10933" } ], "weight": 0.0 }, { "disease_id": "DOID:11206", "name": "opioid abuse", "description": "A substance abuse that involves the recurring use of opioid drugs despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:11206", "evidence": [ { "id": "11206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11206" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11870", "name": "Pick's disease", "description": "A frontotemporal dementia that is characterized by a spectrum of neuropsychiatric symptoms ranging from those that affect the patient's personality to those that cause a decline in cognitive function.", "url": "https://disease-ontology.org/term/DOID:11870", "evidence": [ { "id": "11870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11870" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2560", "name": "morphine dependence", "description": "An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2560", "evidence": [ { "id": "2560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2560" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:670", "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ], "weight": 0.0 }, { "disease_id": "DOID:809", "name": "cocaine abuse", "description": "A substance abuse that involves the recurring use of cocaine despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:809", "evidence": [ { "id": "809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:809" } ], "weight": 0.0 }, { "disease_id": "DOID:8725", "name": "vascular dementia", "description": "A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.", "url": "https://disease-ontology.org/term/DOID:8725", "evidence": [ { "id": "8725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8725" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9973", "name": "substance dependence", "description": "A substance-related disorder that involves the continued use of alcohol or other drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9973", "evidence": [ { "id": "9973", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9973" } ], "weight": 0.0 }, { "disease_id": "DOID:9974", "name": "drug dependence", "description": "A substance dependence that involves the continued use of drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9974", "evidence": [ { "id": "9974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9974" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of circadian sleep/wake cycle, sleep", "id": "GO:0045187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045187", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "learning or memory", "id": "GO:0007611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007611", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "positive regulation of feeding behavior", "id": "GO:2000253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000253", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "sleep", "id": "GO:0030431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030431", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "locomotor rhythm", "id": "GO:0045475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045475", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "thermosensory behavior", "id": "GO:0040040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040040", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "rhythmic behavior", "id": "GO:0007622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007622", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "medium-term memory", "id": "GO:0072375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072375", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "cAMP/PKA signal transduction", "id": "GO:0141156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141156", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWW0-3", "start_pos": "64", "end_pos": "64", "site_lbl": "Thr64", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWW0-3", "start_pos": "181", "end_pos": "181", "site_lbl": "Ser181", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" } ] } ] }, { "uniprot_canonical_ac": "Q9VWW0-3", "start_pos": "184", "end_pos": "184", "site_lbl": "Ser184", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" } ] } ] }, { "uniprot_canonical_ac": "Q9VWW0-3", "start_pos": "186", "end_pos": "186", "site_lbl": "Ser186", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" } ] } ] }, { "uniprot_canonical_ac": "Q9VWW0-3", "start_pos": "216", "end_pos": "216", "site_lbl": "Ser216", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" }, { "database": "iPTMnet", "id": "Q9VWW0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VWW0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" } ] } ] }, { "uniprot_canonical_ac": "Q9VWW0-3", "start_pos": "300", "end_pos": "300", "site_lbl": "Leu300", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "V", "comment": "Fails to block PKA-dependent activation by isoform E; in isoform G.", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" }, { "database": "PubMed", "id": "7651429", "url": "https://glygen.org/publication/PubMed/7651429" } ] } ] }, { "uniprot_canonical_ac": "Q9VWW0-3", "start_pos": "307", "end_pos": "307", "site_lbl": "Leu307", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "V", "comment": "Fails to block PKA-dependent activation by isoform E; in isoform G.", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW0", "url": "https://www.uniprot.org/uniprotkb/Q9VWW0" }, { "database": "PubMed", "id": "7651429", "url": "https://glygen.org/publication/PubMed/7651429" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VX31-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1105, "chemical_mass": 124890.0, "gene_names": "IntS2;CG8211;Dmel\\CG8211;Int2;IntS2;intS2", "protein_name": "Integrator complex subunit 2", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" }, { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "Q9VX31", "url": "https://www.uniprot.org/uniprotkb/Q9VX31" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VX31-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Thr371", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 371, "start_aa": "Thr", "end_pos": 371, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr371", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VX36-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 242, "chemical_mass": 26782.0, "gene_names": "ND-24;BEST:LP01573;CG 5703;CG5703;Dmel\\CG5703;Dmel_CG5703;ND-24;ND24;NDUFV2;NUHM;Ndufv2;Q9VX36;dNDUFV2A;dNDUFV2", "protein_name": "", "disease": [ { "disease_id": "DOID:0112092", "name": "nuclear type mitochondrial complex I deficiency 7", "description": "A nuclear type mitochondrial complex I deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the NDUFV2 gene on chromosome 18p11.22.", "url": "https://disease-ontology.org/term/DOID:0112092", "evidence": [ { "id": "0112092", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112092" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:700", "name": "mitochondrial metabolism disease", "description": "An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.", "url": "https://disease-ontology.org/term/DOID:700", "evidence": [ { "id": "700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:700" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "pmid": "" }, { "name": "NADH dehydrogenase (ubiquinone) activity", "id": "GO:0008137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008137", "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "Q9VX36", "url": "https://www.uniprot.org/uniprotkb/Q9VX36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VX98-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 189, "chemical_mass": 21349.0, "gene_names": "DENR;CG9099;DENR;Dmel\\CG9099", "protein_name": "Density-regulated protein homolog", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "biological_process": [ { "name": "translation reinitiation", "id": "GO:0002188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002188", "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "pmid": "" }, { "name": "positive regulation of insulin receptor signaling pathway", "id": "GO:0046628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046628", "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "pmid": "" }, { "name": "positive regulation of ecdysone receptor signaling pathway", "id": "GO:0120142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120142", "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "pmid": "" } ], "molecular_function": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "pmid": "" }, { "name": "mRNA 5'-UTR binding", "id": "GO:0048027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048027", "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "pmid": "" } ], "cellular_component": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q9VX98", "url": "https://www.uniprot.org/uniprotkb/Q9VX98" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VXA8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 375, "chemical_mass": 42903.0, "gene_names": "Rai1;CG32566;CG9125;Dmel\\CG9125;Rai1;dRai1", "protein_name": "Decapping and exoribonuclease protein Rai1", "disease": [], "molecular_function": [ { "name": "mRNA 5'-diphosphatase activity", "id": "GO:0034353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034353", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" }, { "name": "5'-3' RNA exonuclease activity", "id": "GO:0004534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004534", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" }, { "name": "RNA NAD+-cap (NAD+-forming) hydrolase activity", "id": "GO:0110152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110152", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" }, { "name": "NAD-cap decapping", "id": "GO:0110155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110155", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA8", "url": "https://www.uniprot.org/uniprotkb/Q9VXA8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VXG4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 511, "chemical_mass": 56215.0, "gene_names": "AnxB11;ANXB11;AnxB11;Anxb11;Axb11;BcDNA:GH16395;CG9968;Dmel\\CG9968;annexin", "protein_name": "Annexin B11", "disease": [ { "disease_id": "DOID:0060060", "name": "non-Hodgkin lymphoma", "description": "A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma.", "url": "https://disease-ontology.org/term/DOID:0060060", "evidence": [ { "id": "0060060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060060" } ], "weight": 0.0 }, { "disease_id": "DOID:0080225", "name": "amyotrophic lateral sclerosis type 23", "description": "An amyotrophic lateral sclerosis that has_material_basis_in heterozygous mutation in the ANXA11 gene on chromosome 10q22.", "url": "https://disease-ontology.org/term/DOID:0080225", "evidence": [ { "id": "0080225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080225" } ], "weight": 0.0 }, { "disease_id": "DOID:0081121", "name": "inclusion body myopathy and brain white matter abnormalities", "description": "An inclusion body myopathy with Paget disease of bone and frontotemporal dementia that is characterized by proximal limb girdle muscle weakness affecting the lower and upper limbs and resulting in gait difficulties and scapular winging and that has_material_basis_in heterozygous mutation in the ANXA11 gene on chromosome 10q22.", "url": "https://disease-ontology.org/term/DOID:0081121", "evidence": [ { "id": "0081121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081121" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:11383", "name": "cryptorchidism", "description": "", "url": "https://disease-ontology.org/term/DOID:11383", "evidence": [ { "id": "11383", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11383" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:4159", "name": "skin cancer", "description": "An integumentary system cancer located_in the skin that is the uncontrolled growth of abnormal skin cells.", "url": "https://disease-ontology.org/term/DOID:4159", "evidence": [ { "id": "4159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4159" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 }, { "disease_id": "DOID:893", "name": "Wilson disease", "description": "A metal metabolism disease that is characterized by excess copper stored in various body tissues, particularly the liver, brain, and corneas of the eyes.", "url": "https://disease-ontology.org/term/DOID:893", "evidence": [ { "id": "893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:893" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "pmid": "" } ], "biological_process": [ { "name": "response to calcium ion", "id": "GO:0051592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051592", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG4", "url": "https://www.uniprot.org/uniprotkb/Q9VXG4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VXG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2517, "chemical_mass": 289330.0, "gene_names": "mei-41;4252;ATR;CG4252;DmATR;Dmel\\CG4252;Dmmei41;MEI41/FRP1;MEI41;Mei-41/DATR;Mei-41;Mei41;atr;dATR;fs(1)M37;mei-195;mei-41;mei41;meiP41;mus(1)103;mus(1)104;mus-103;mus-104;mus103;mus104", "protein_name": "Serine/threonine-protein kinase ATR", "disease": [ { "disease_id": "DOID:0050569", "name": "Seckel syndrome", "description": "A syndrome characterized by intrauterine growth retardation and postnatal dwarfism with microcephaly and intellectual disability.", "url": "https://disease-ontology.org/term/DOID:0050569", "evidence": [ { "id": "0050569", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050569" } ], "weight": 0.0 }, { "disease_id": "DOID:0060060", "name": "non-Hodgkin lymphoma", "description": "A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma.", "url": "https://disease-ontology.org/term/DOID:0060060", "evidence": [ { "id": "0060060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060060" } ], "weight": 0.0 }, { "disease_id": "DOID:0070007", "name": "Seckel syndrome 1", "description": "A Seckel syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the ATR gene on chromosome 3q23.", "url": "https://disease-ontology.org/term/DOID:0070007", "evidence": [ { "id": "0070007", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070007" } ], "weight": 0.0 }, { "disease_id": "DOID:0080202", "name": "adenoid cystic carcinoma", "description": "An adenocarcinoma that is characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells.", "url": "https://disease-ontology.org/term/DOID:0080202", "evidence": [ { "id": "0080202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080202" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12704", "name": "ataxia telangiectasia", "description": "An autosomal recessive cerebellar ataxia that is characterized by cerebellar ataxia, telangiectases, immune defects, and a predisposition to malignancy and that has_material_basis_in homozygous or compound heterozygous mutation in the ATM gene on chromosome 11q22.", "url": "https://disease-ontology.org/term/DOID:12704", "evidence": [ { "id": "12704", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12704" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon.", "url": "https://disease-ontology.org/term/DOID:219", "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ], "weight": 0.0 }, { "disease_id": "DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.", "url": "https://disease-ontology.org/term/DOID:9261", "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ], "weight": 0.0 } ], "biological_process": [ { "name": "female meiosis chromosome segregation", "id": "GO:0016321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016321", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "double-strand break repair via single-strand annealing", "id": "GO:0045002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045002", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "response to radiation", "id": "GO:0009314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009314", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle phase transition", "id": "GO:1901990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901990", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "meiotic DNA double-strand break processing", "id": "GO:0000706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000706", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "regulation of double-strand break repair", "id": "GO:2000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000779", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "double-strand break repair via synthesis-dependent strand annealing", "id": "GO:0045003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045003", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "regulation of syncytial blastoderm mitotic cell cycle", "id": "GO:0007348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007348", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "cellularization", "id": "GO:0007349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007349", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "imaginal disc development", "id": "GO:0007444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007444", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "oocyte fate determination", "id": "GO:0030716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030716", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "1569", "end_pos": "1569", "site_lbl": "Ser1569", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VXG8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VXG8" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "1570", "end_pos": "1570", "site_lbl": "Tyr1570", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VXG8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VXG8" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "1573", "end_pos": "1573", "site_lbl": "Ser1573", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VXG8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VXG8" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "1575", "end_pos": "1575", "site_lbl": "Thr1575", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VXG8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VXG8" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "2032", "end_pos": "2032", "site_lbl": "His2032", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "In mei-41D12; induces a weak sensitivity to methanesulfonate.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "12807779", "url": "https://glygen.org/publication/PubMed/12807779" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "2322", "end_pos": "2322", "site_lbl": "Pro2322", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "In mei-41D5; induces a strong sensitivity to methanesulfonate.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "12807779", "url": "https://glygen.org/publication/PubMed/12807779" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "253", "end_pos": "253", "site_lbl": "Trp253", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "T", "comment": "In mei-41D12; induces a weak sensitivity to methanesulfonate.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "12807779", "url": "https://glygen.org/publication/PubMed/12807779" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Ala647", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "V", "comment": "In mei-41D3; induces a very strong sensitivity to methanesulfonate and female infertility.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "12807779", "url": "https://glygen.org/publication/PubMed/12807779" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "810", "end_pos": "810", "site_lbl": "Ser810", "weight": 0.0, "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "F", "comment": "In mei-41D9; induces some sensitivity to methanesulfonate.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "12807779", "url": "https://glygen.org/publication/PubMed/12807779" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "815", "end_pos": "815", "site_lbl": "Thr815", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "P", "comment": "In mei-41D15; induces some sensitivity to methanesulfonate.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "12807779", "url": "https://glygen.org/publication/PubMed/12807779" } ] } ] }, { "uniprot_canonical_ac": "Q9VXG8-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Leu818", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "F", "comment": "In mei-41D14; induces some sensitivity to methanesulfonate.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXG8", "url": "https://www.uniprot.org/uniprotkb/Q9VXG8" }, { "database": "PubMed", "id": "12807779", "url": "https://glygen.org/publication/PubMed/12807779" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VXJ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 598, "chemical_mass": 64073.0, "gene_names": "Mfe2;CG3415;DBP;DmMFE-2;Dmel\\CG3415;Dmel_CG3415;HSD17B4;MFE-2;MFE2;Mfe2", "protein_name": "Peroxisomal multifunctional enzyme type 2", "disease": [ { "disease_id": "DOID:0050857", "name": "Perrault syndrome", "description": "A syndrome that is characterized by sensorineural hearing loss and ovarian failure.", "url": "https://disease-ontology.org/term/DOID:0050857", "evidence": [ { "id": "0050857", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050857" } ], "weight": 0.0 }, { "disease_id": "DOID:0090031", "name": "D-bifunctional protein deficiency", "description": "A peroxisomal disease characterized by, in severe cases, infantile-onset of hypotonia, seizures, and abnormal facial features with most dying before age 2 years that has_material_basis_in homozygous or compound heterozygous mutation in the HSD17B4 gene on chromosome 5q2.", "url": "https://disease-ontology.org/term/DOID:0090031", "evidence": [ { "id": "0090031", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090031" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:13366", "name": "Stiff-Person syndrome", "description": "A movement disease that is of unknown etiology characterized by progressive rigidity.", "url": "https://disease-ontology.org/term/DOID:13366", "evidence": [ { "id": "13366", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13366" } ], "weight": 0.0 }, { "disease_id": "DOID:3146", "name": "lipid metabolism disorder", "description": "An inherited metabolic disorder that involves the creation and degradation of lipids.", "url": "https://disease-ontology.org/term/DOID:3146", "evidence": [ { "id": "3146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3146" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation using acyl-CoA oxidase", "id": "GO:0033540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033540", "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "estradiol 17-beta-dehydrogenase [NAD(P)+] activity", "id": "GO:0004303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004303", "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "pmid": "" }, { "name": "(2E)-enoyl-CoA hydratase activity", "id": "GO:0080023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080023", "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "pmid": "" }, { "name": "(3R)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity", "id": "GO:0106386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106386", "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "pmid": "" }, { "name": "3-hydroxyacyl-CoA dehydratase activity", "id": "GO:0018812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018812", "evidence": [ { "database": "UniProtKB", "id": "Q9VXJ0", "url": "https://www.uniprot.org/uniprotkb/Q9VXJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VXJ0-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Thr198", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 198, "start_aa": "Thr", "end_pos": 198, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr198", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VXT2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXT2", "url": "https://www.uniprot.org/uniprotkb/Q9VXT2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 333, "chemical_mass": 39887.0, "gene_names": "CG7872;Dmel\\CG7872", "protein_name": "DnaJ homolog subfamily C member 25 homolog", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT2", "url": "https://www.uniprot.org/uniprotkb/Q9VXT2" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT2", "url": "https://www.uniprot.org/uniprotkb/Q9VXT2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT2", "url": "https://www.uniprot.org/uniprotkb/Q9VXT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VXT5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXT5", "url": "https://www.uniprot.org/uniprotkb/Q9VXT5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 687, "chemical_mass": 78149.0, "gene_names": "Dmel\\CG9213;CG32585;CG9213;Dmel\\CG9213;Dmel_CG9213", "protein_name": "CWF19-like protein 2 homolog", "disease": [], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT5", "url": "https://www.uniprot.org/uniprotkb/Q9VXT5" } ], "pmid": "" } ], "cellular_component": [ { "name": "post-mRNA release spliceosomal complex", "id": "GO:0071014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071014", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT5", "url": "https://www.uniprot.org/uniprotkb/Q9VXT5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VXT5-1", "start_pos": "128", "end_pos": "128", "site_lbl": "Ser128", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT5", "url": "https://www.uniprot.org/uniprotkb/Q9VXT5" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VXT5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VXT5" } ] } ] }, { "uniprot_canonical_ac": "Q9VXT5-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Ser130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT5", "url": "https://www.uniprot.org/uniprotkb/Q9VXT5" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VXT5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VXT5" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VXY0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXY0", "url": "https://www.uniprot.org/uniprotkb/Q9VXY0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 495, "chemical_mass": 57189.0, "gene_names": "Cyp4s3;4s3;CG9081;Cyp4s3;Dmel\\CG9081;RE63964", "protein_name": "Probable cytochrome P450 4s3", "disease": [ { "disease_id": "DOID:0050664", "name": "Bietti crystalline corneoretinal dystrophy", "description": "A retinal degeneration that is characterized by crystals in the cornea, shiny deposits on the retina and progressive atrophy of the retina, choriocapillaris and choroid, has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the CYP4V2 gene on chromosome 4q35.", "url": "https://disease-ontology.org/term/DOID:0050664", "evidence": [ { "id": "0050664", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050664" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VXY0", "url": "https://www.uniprot.org/uniprotkb/Q9VXY0" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VXY0", "url": "https://www.uniprot.org/uniprotkb/Q9VXY0" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VXY0", "url": "https://www.uniprot.org/uniprotkb/Q9VXY0" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VXY0", "url": "https://www.uniprot.org/uniprotkb/Q9VXY0" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VXY0", "url": "https://www.uniprot.org/uniprotkb/Q9VXY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VXY0-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Thr39", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VY20-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 285, "chemical_mass": 32861.0, "gene_names": "Dmel\\CG5347;CG5347;Dmel\\CG5347;Dmel_CG5347", "protein_name": "RING-type E3 ubiquitin transferase", "disease": [ { "disease_id": "DOID:0112309", "name": "central precocious puberty 2", "description": "A central precocious puberty that has_material_basis_in heterozygous mutation on the paternal allele of the MKRN3 gene on chromosome 15q11.2.", "url": "https://disease-ontology.org/term/DOID:0112309", "evidence": [ { "id": "0112309", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112309" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "Q9VY20", "url": "https://www.uniprot.org/uniprotkb/Q9VY20" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYB0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 249, "chemical_mass": 27774.0, "gene_names": "BthD;BthD;CG11177;Dmel\\CG11177;SelH;dSelH;dselH;dselM", "protein_name": "Selenoprotein BthD", "disease": [ { "disease_id": "DOID:0050860", "name": "colorectal adenoma", "description": "An intestinal benign neoplasm that has_material_basis_in epithelial tissue of glandular origin and is located_in colon and located_in rectum.", "url": "https://disease-ontology.org/term/DOID:0050860", "evidence": [ { "id": "0050860", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050860" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 } ], "biological_process": [ { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" }, { "name": "response to redox state", "id": "GO:0051775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051775", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" }, { "name": "salivary gland boundary specification", "id": "GO:0007432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007432", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" }, { "name": "larval salivary gland morphogenesis", "id": "GO:0007436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007436", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VYB0-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Ser147", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VYB0", "url": "https://www.uniprot.org/uniprotkb/Q9VYB0" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VYB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VYB0" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYF8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYF8", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 301, "chemical_mass": 34338.0, "gene_names": "Coq5;CG2453;Coq5;Dmel\\CG2453;Dmel_CG2453", "protein_name": "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "disease": [ { "disease_id": "DOID:0050730", "name": "coenzyme Q10 deficiency disease", "description": "A mitochondrial metabolism disease that is characterized by a deficiency of CoQ10 resulting from reduced biosynthesis.", "url": "https://disease-ontology.org/term/DOID:0050730", "evidence": [ { "id": "0050730", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050730" } ], "weight": 0.0 }, { "disease_id": "DOID:0112138", "name": "primary coenzyme Q10 deficiency 9", "description": "A coenzyme Q10 deficiency disease characterized by onset in the first decade of life of cerebellar ataxia associated with cerebellar atrophy that has_material_basis_in mutation homozygous or compound heterozygous in the COQ5 gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0112138", "evidence": [ { "id": "0112138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112138" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "Q9VYF8", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VYF8", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ], "pmid": "" }, { "name": "ubiquinone biosynthesis complex", "id": "GO:0110142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110142", "evidence": [ { "database": "UniProtKB", "id": "Q9VYF8", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ], "pmid": "" } ], "biological_process": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "Q9VYF8", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q9VYF8", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ], "pmid": "" } ], "molecular_function": [ { "name": "2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity", "id": "GO:0008425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008425", "evidence": [ { "database": "UniProtKB", "id": "Q9VYF8", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 515, "chemical_mass": 58170.0, "gene_names": "Bap60;BAF60;BAP60;BAPp60;Bap60;CG4303;Dmel\\CG4303;bap60;dBAP60;i127;i133", "protein_name": "Brahma-associated protein of 60 kDa", "disease": [ { "disease_id": "DOID:0112372", "name": "Coffin-Siris syndrome 11", "description": "A Coffin-Siris syndrome characterized by global developmental delay and impaired intellectual development associated with hypotonia, feeding difficulties, and variable dysmorphic features that has_material_basis_in heterozygous mutation in the SMARCD1 gene on chromosome 12q13.12.", "url": "https://disease-ontology.org/term/DOID:0112372", "evidence": [ { "id": "0112372", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112372" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1925", "name": "Coffin-Siris syndrome", "description": "An autosomal dominant intellectual developmental disorder that is characterized by mental retardation associated with coarse facial features, hypertrichosis, sparse scalp hair, and hypoplastic or absent fifth fingernails or toenails.", "url": "https://disease-ontology.org/term/DOID:1925", "evidence": [ { "id": "1925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1925" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "myosin binding", "id": "GO:0017022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "brahma complex", "id": "GO:0035060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035060", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "negative regulation of neuroblast proliferation", "id": "GO:0007406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007406", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" }, { "name": "positive regulation of heterochromatin formation", "id": "GO:0031453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031453", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VYG2-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Lys158", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of DNA-binding. Does not affect function in vivo; when associated with A-166 and A-185.", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" }, { "database": "PubMed", "id": "16083904", "url": "https://glygen.org/publication/PubMed/16083904" } ] } ] }, { "uniprot_canonical_ac": "Q9VYG2-1", "start_pos": "166", "end_pos": "166", "site_lbl": "Lys166", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of DNA-binding. Does not affect function in vivo; when associated with A-158 and A-185.", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" }, { "database": "PubMed", "id": "16083904", "url": "https://glygen.org/publication/PubMed/16083904" } ] } ] }, { "uniprot_canonical_ac": "Q9VYG2-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Arg185", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Loss of DNA-binding. Does not affect function in vivo; when associated with A-158 and A-166.", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG2", "url": "https://www.uniprot.org/uniprotkb/Q9VYG2" }, { "database": "PubMed", "id": "16083904", "url": "https://glygen.org/publication/PubMed/16083904" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VYQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 483, "chemical_mass": 54790.0, "gene_names": "Cyp311a1;311a1;CG1488;CYP311A1;Cyp311a1;Dmel\\CG1488", "protein_name": "Probable cytochrome P450 311a1", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VYQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VYQ7" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VYQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VYQ7" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VYQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VYQ7" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VYQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VYQ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VYQ7", "url": "https://www.uniprot.org/uniprotkb/Q9VYQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYS4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1373, "chemical_mass": 151312.0, "gene_names": "wisp;CG15737;DmCG15737;Dmel\\CG15737;Dmel_CG15737;PAP;TAMP;TUTase2;Wispy;Wisp;fs(1)M19;wisp", "protein_name": "Poly(A) RNA polymerase gld-2 homolog B", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "poly(A) RNA polymerase activity", "id": "GO:1990817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990817", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" } ], "biological_process": [ { "name": "oocyte maturation", "id": "GO:0001556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001556", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "pronuclear fusion", "id": "GO:0007344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007344", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "egg activation", "id": "GO:0007343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007343", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "spindle assembly involved in female meiosis", "id": "GO:0007056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007056", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "positive regulation of antibacterial peptide biosynthetic process", "id": "GO:0006963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006963", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "sperm aster formation", "id": "GO:0035044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035044", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "pronuclear migration", "id": "GO:0035046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035046", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "cytosolic mRNA polyadenylation", "id": "GO:0180011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180011", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q9VYS4", "url": "https://www.uniprot.org/uniprotkb/Q9VYS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VYS4-1", "start_pos": "860", "end_pos": "860", "site_lbl": "Thr860", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 860, "start_aa": "Thr", "end_pos": 860, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr860", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VYS4-1", "start_pos": "926", "end_pos": "926", "site_lbl": "Thr926", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 926, "start_aa": "Thr", "end_pos": 926, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr926", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYV5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYV5", "url": "https://www.uniprot.org/uniprotkb/Q9VYV5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 619, "chemical_mass": 70206.0, "gene_names": "FucT6;6-FucT;BEST:CK00490;CG2448;CK00490;Dm alpha1;Dmel\\CG2448;Fuc-TVIII;FucT6;dalpha6Fut", "protein_name": "Alpha-(1,6)-fucosyltransferase", "disease": [ { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "alpha-(1->6)-fucosyltransferase activity", "id": "GO:0046921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046921", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV5", "url": "https://www.uniprot.org/uniprotkb/Q9VYV5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV5", "url": "https://www.uniprot.org/uniprotkb/Q9VYV5" } ], "pmid": "" }, { "name": "glycoprotein 6-alpha-L-fucosyltransferase activity", "id": "GO:0008424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008424", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV5", "url": "https://www.uniprot.org/uniprotkb/Q9VYV5" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV5", "url": "https://www.uniprot.org/uniprotkb/Q9VYV5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV5", "url": "https://www.uniprot.org/uniprotkb/Q9VYV5" } ], "pmid": "" }, { "name": "GDP-L-fucose metabolic process", "id": "GO:0046368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046368", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV5", "url": "https://www.uniprot.org/uniprotkb/Q9VYV5" } ], "pmid": "" }, { "name": "Golgi apparatus N-glycan diversification", "id": "GO:0016258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016258", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV5", "url": "https://www.uniprot.org/uniprotkb/Q9VYV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYY4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYY4", "url": "https://www.uniprot.org/uniprotkb/Q9VYY4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 574, "chemical_mass": 65380.0, "gene_names": "Cyp4g15;152658_at;4g15;CG11715;CYP4G15;Cyp4g15;Dmel\\CG11715;cyp4g15", "protein_name": "Cytochrome P450 4g15", "disease": [ { "disease_id": "DOID:0050664", "name": "Bietti crystalline corneoretinal dystrophy", "description": "A retinal degeneration that is characterized by crystals in the cornea, shiny deposits on the retina and progressive atrophy of the retina, choriocapillaris and choroid, has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the CYP4V2 gene on chromosome 4q35.", "url": "https://disease-ontology.org/term/DOID:0050664", "evidence": [ { "id": "0050664", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050664" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY4", "url": "https://www.uniprot.org/uniprotkb/Q9VYY4" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY4", "url": "https://www.uniprot.org/uniprotkb/Q9VYY4" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY4", "url": "https://www.uniprot.org/uniprotkb/Q9VYY4" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY4", "url": "https://www.uniprot.org/uniprotkb/Q9VYY4" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY4", "url": "https://www.uniprot.org/uniprotkb/Q9VYY4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 807, "chemical_mass": 92782.0, "gene_names": "Evi5;BcDNA:GH08923;BcDNA:LD11130;CG11727;Dmel\\CG11727;Evi5;MRE21", "protein_name": "Ecotropic viral integration site 5 ortholog", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VYY9-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VYY9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VYY9" } ] } ] }, { "uniprot_canonical_ac": "Q9VYY9-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Ser58", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VYY9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VYY9" } ] } ] }, { "uniprot_canonical_ac": "Q9VYY9-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Ser64", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VYY9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VYY9" } ] } ] }, { "uniprot_canonical_ac": "Q9VYY9-1", "start_pos": "160", "end_pos": "160", "site_lbl": "Arg160", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Does not affect subcellular location or interaction with Rab11. Fails to inactivate Rab11.", "evidence": [ { "database": "UniProtKB", "id": "Q9VYY9", "url": "https://www.uniprot.org/uniprotkb/Q9VYY9" }, { "database": "PubMed", "id": "22778279", "url": "https://glygen.org/publication/PubMed/22778279" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VYZ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 373, "chemical_mass": 44030.0, "gene_names": "Gr10b;CG12622;Dmel\\CG12622;GR10b;Gr10B2;Gr10b", "protein_name": "Putative gustatory receptor 10b", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZ49-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 592, "chemical_mass": 63596.0, "gene_names": "Arlr;CG2145;Dmel\\CG2145;Dmel_CG2145", "protein_name": "Endoribonuclease Arlr", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" }, { "name": "ribonuclease T2 activity", "id": "GO:0033897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033897", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of lipid catabolic process", "id": "GO:0050995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050995", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" }, { "name": "post-transcriptional gene silencing", "id": "GO:0016441", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016441", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ49", "url": "https://www.uniprot.org/uniprotkb/Q9VZ49" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Thr133", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 133, "start_aa": "Thr", "end_pos": 133, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr133", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Thr245", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 245, "start_aa": "Thr", "end_pos": 245, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr245", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "247", "end_pos": "247", "site_lbl": "Thr247", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 247, "start_aa": "Thr", "end_pos": 247, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "260", "end_pos": "260", "site_lbl": "Thr260", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "278", "end_pos": "278", "site_lbl": "Thr278", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 278, "start_aa": "Thr", "end_pos": 278, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr278", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "280", "end_pos": "280", "site_lbl": "Thr280", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 280, "start_aa": "Thr", "end_pos": 280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr280", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Thr282", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "292", "end_pos": "292", "site_lbl": "Thr292", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 292, "start_aa": "Thr", "end_pos": 292, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr292", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZ49-1", "start_pos": "84", "end_pos": "84", "site_lbl": "Thr84", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 84, "start_aa": "Thr", "end_pos": 84, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr84", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZ64-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ64", "url": "https://www.uniprot.org/uniprotkb/Q9VZ64" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 243, "chemical_mass": 26672.0, "gene_names": "Pgls;6PGL;CG17333;Dm6PGL;Dmel\\CG17333;PGLS;Pgls", "protein_name": "Probable 6-phosphogluconolactonase", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ64", "url": "https://www.uniprot.org/uniprotkb/Q9VZ64" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ64", "url": "https://www.uniprot.org/uniprotkb/Q9VZ64" } ], "pmid": "" }, { "name": "pentose-phosphate shunt, oxidative branch", "id": "GO:0009051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009051", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ64", "url": "https://www.uniprot.org/uniprotkb/Q9VZ64" } ], "pmid": "" } ], "molecular_function": [ { "name": "6-phosphogluconolactonase activity", "id": "GO:0017057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017057", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ64", "url": "https://www.uniprot.org/uniprotkb/Q9VZ64" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZD2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZD2", "url": "https://www.uniprot.org/uniprotkb/Q9VZD2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 238, "chemical_mass": 28070.0, "gene_names": "CG11342;Dmel\\CG11342", "protein_name": "Probable RNA methyltransferase CG11342", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZD2", "url": "https://www.uniprot.org/uniprotkb/Q9VZD2" } ], "pmid": "" } ], "biological_process": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q9VZD2", "url": "https://www.uniprot.org/uniprotkb/Q9VZD2" } ], "pmid": "" }, { "name": "negative regulation of pre-miRNA processing", "id": "GO:2000632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000632", "evidence": [ { "database": "UniProtKB", "id": "Q9VZD2", "url": "https://www.uniprot.org/uniprotkb/Q9VZD2" } ], "pmid": "" } ], "molecular_function": [ { "name": "O-methyltransferase activity", "id": "GO:0008171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008171", "evidence": [ { "database": "UniProtKB", "id": "Q9VZD2", "url": "https://www.uniprot.org/uniprotkb/Q9VZD2" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "Q9VZD2", "url": "https://www.uniprot.org/uniprotkb/Q9VZD2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZE6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZE6", "url": "https://www.uniprot.org/uniprotkb/Q9VZE6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 359, "chemical_mass": 41618.0, "gene_names": "CG11583;CG32253;Dmel\\CG11583;dBRX1", "protein_name": "Ribosome biogenesis protein BRX1 homolog", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE6", "url": "https://www.uniprot.org/uniprotkb/Q9VZE6" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE6", "url": "https://www.uniprot.org/uniprotkb/Q9VZE6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE6", "url": "https://www.uniprot.org/uniprotkb/Q9VZE6" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE6", "url": "https://www.uniprot.org/uniprotkb/Q9VZE6" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE6", "url": "https://www.uniprot.org/uniprotkb/Q9VZE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZH1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZH1", "url": "https://www.uniprot.org/uniprotkb/Q9VZH1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 291, "chemical_mass": 33117.0, "gene_names": "CG18675;Dmel\\CG18675", "protein_name": "Cilia- and flagella-associated protein 298", "disease": [ { "disease_id": "DOID:0110627", "name": "primary ciliary dyskinesia 26", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with inner and outer dynein arm defect, neonatal respiratory distress, recurrent upper and lower airway disease, bronchiectasis, and variable occurence of laterality defects and has_material_basis_in homozygous or compound heterozygous mutation in the C21ORF59 gene on chromosome 21q22.", "url": "https://disease-ontology.org/term/DOID:0110627", "evidence": [ { "id": "0110627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110627" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of cilium movement", "id": "GO:0003352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003352", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH1", "url": "https://www.uniprot.org/uniprotkb/Q9VZH1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZH2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1047, "chemical_mass": 111564.0, "gene_names": "mas;CG15002;Dmel\\CG15002;Mas;SPH79;c-SPH79;cSPH79;mas", "protein_name": "Protein masquerade", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "peripheral nervous system development", "id": "GO:0007422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007422", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "neuron projection fasciculation", "id": "GO:0106030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106030", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" }, { "name": "somatic muscle attachment to chitin-based cuticle", "id": "GO:0160175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160175", "evidence": [ { "database": "UniProtKB", "id": "Q9VZH2", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "251", "end_pos": "251", "site_lbl": "Asn251", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 251, "start_aa": "Asn", "end_pos": 251, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn251", "evidence": [ { "id": "Q9VZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "287", "end_pos": "287", "site_lbl": "Asn287", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 287, "start_aa": "Asn", "end_pos": 287, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn287", "evidence": [ { "id": "Q9VZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "382", "end_pos": "382", "site_lbl": "Thr382", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "507", "end_pos": "507", "site_lbl": "Thr507", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 507, "start_aa": "Thr", "end_pos": 507, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr507", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "511", "end_pos": "511", "site_lbl": "Thr511", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 511, "start_aa": "Thr", "end_pos": 511, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr511", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "582", "end_pos": "582", "site_lbl": "Asn582", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 582, "start_aa": "Asn", "end_pos": 582, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn582", "evidence": [ { "id": "Q9VZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "726", "end_pos": "726", "site_lbl": "Asn726", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 726, "start_aa": "Asn", "end_pos": 726, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn726", "evidence": [ { "id": "Q9VZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "794", "end_pos": "794", "site_lbl": "Asn794", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 794, "start_aa": "Asn", "end_pos": 794, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn794", "evidence": [ { "id": "Q9VZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9VZH2-1", "start_pos": "95", "end_pos": "95", "site_lbl": "Asn95", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 95, "start_aa": "Asn", "end_pos": 95, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn95", "evidence": [ { "id": "Q9VZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZH2#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZI2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1073, "chemical_mass": 118418.0, "gene_names": "Ack;ACK2;ACK;Ack;BcDNA:GH10777;CG14992;DACK;DAck;Dmel\\CG14992;dACK;p145", "protein_name": "Activated Cdc42 kinase Ack", "disease": [], "biological_process": [ { "name": "myosin filament assembly", "id": "GO:0031034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031034", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "cellular response to epidermal growth factor stimulus", "id": "GO:0071364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071364", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "sperm individualization", "id": "GO:0007291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007291", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "CTP biosynthetic process", "id": "GO:0006241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006241", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "dorsal closure", "id": "GO:0007391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007391", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "head involution", "id": "GO:0008258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008258", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "dorsal closure, amnioserosa morphology change", "id": "GO:0046664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046664", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" }, { "name": "cytoophidium", "id": "GO:0097268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097268", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZI2-1", "start_pos": "502", "end_pos": "502", "site_lbl": "Thr502", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 502, "start_aa": "Thr", "end_pos": 502, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr502", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VZI2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VZI2" } ] } ] }, { "uniprot_canonical_ac": "Q9VZI2-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Lys156", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of enzyme activity. Increase in apoptotic cells in the eye and wing. Increase in bristle number in the interommatidial lattice and decrease in pigment cell number. Disrupts vesicular localization of dock in spermatocytes. Fails to rescue the nurse cell plasma membrane defects and male sterility observed in null mutants. Fails to rescue the small eye phenotype induced by hid but able to rescue the small eye phenotype induced by rpr.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" }, { "database": "PubMed", "id": "23562806", "url": "https://glygen.org/publication/PubMed/23562806" }, { "database": "PubMed", "id": "22615583", "url": "https://glygen.org/publication/PubMed/22615583" }, { "database": "PubMed", "id": "11773052", "url": "https://glygen.org/publication/PubMed/11773052" }, { "database": "PubMed", "id": "25223282", "url": "https://glygen.org/publication/PubMed/25223282" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of enzyme activity. Many embryos die before hatching. Fails to promote yki-dependent tissue growth in the eye and wing. Overexpression in wing imaginal disks frequently results in wings with blisters and ectopic veins. Eyes are disorganized and ommatidia are almost completely absent, eye bristles are not present in posterior two-thirds of the eye and bristle clusters occur at the anterior end. Increased Egfr endocytosis in embryos. No effect on Dpp expression in the leading edge cells.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZI2", "url": "https://www.uniprot.org/uniprotkb/Q9VZI2" }, { "database": "PubMed", "id": "23579691", "url": "https://glygen.org/publication/PubMed/23579691" }, { "database": "PubMed", "id": "11997505", "url": "https://glygen.org/publication/PubMed/11997505" }, { "database": "PubMed", "id": "27462444", "url": "https://glygen.org/publication/PubMed/27462444" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZJ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 417, "chemical_mass": 48869.0, "gene_names": "Gr64d;CG14987;CG33157;Dmel64d;Dmel\\CG14987;GR64d;Gr64d;Gr64", "protein_name": "Gustatory receptor for sugar taste 64d", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of taste", "id": "GO:0050912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050912", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "sensory perception of sweet taste", "id": "GO:0050916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050916", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "proboscis extension reflex", "id": "GO:0007637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007637", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "sweet taste receptor activity", "id": "GO:0033041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033041", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "ionotropic taste receptor activity", "id": "GO:0170021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170021", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" }, { "name": "ionotropic sweet taste receptor activity", "id": "GO:0170023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170023", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ6", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZJ6-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Asn130", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 130, "start_aa": "Asn", "end_pos": 130, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn130", "evidence": [ { "id": "Q9VZJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ6#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9VZJ6-1", "start_pos": "372", "end_pos": "372", "site_lbl": "Thr372", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 372, "start_aa": "Thr", "end_pos": 372, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr372", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZJ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 338, "chemical_mass": 37844.0, "gene_names": "Mul1;CG1134;Dmel\\CG1134;MUL1;Mul1;mul1", "protein_name": "Mitochondrial E3 ubiquitin protein ligase 1", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZJ9-1", "start_pos": "307", "end_pos": "307", "site_lbl": "His307", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes ligase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ9" }, { "database": "PubMed", "id": "24898855", "url": "https://glygen.org/publication/PubMed/24898855" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZM7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZM7", "url": "https://www.uniprot.org/uniprotkb/Q9VZM7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 631, "chemical_mass": 72257.0, "gene_names": "IntS10;CG1120;Dmel\\CG1120;Int10;IntS10", "protein_name": "Integrator complex subunit 10", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VZM7", "url": "https://www.uniprot.org/uniprotkb/Q9VZM7" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "Q9VZM7", "url": "https://www.uniprot.org/uniprotkb/Q9VZM7" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "Q9VZM7", "url": "https://www.uniprot.org/uniprotkb/Q9VZM7" } ], "pmid": "" } ], "biological_process": [ { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "Q9VZM7", "url": "https://www.uniprot.org/uniprotkb/Q9VZM7" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "Q9VZM7", "url": "https://www.uniprot.org/uniprotkb/Q9VZM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZS3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 110, "chemical_mass": 12450.0, "gene_names": "eIF1;BcDNA:RE14985;CG17737;Dmel\\CG17737;EIF1;anon-EST:Posey272;dEIF1;eIF1", "protein_name": "Eukaryotic translation initiation factor eIF1", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "pmid": "" }, { "name": "formation of translation preinitiation complex", "id": "GO:0001731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001731", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "pmid": "" }, { "name": "multi-eIF complex", "id": "GO:0043614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043614", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZS3-1", "start_pos": "40", "end_pos": "40", "site_lbl": "Thr40", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VZS3", "url": "https://www.uniprot.org/uniprotkb/Q9VZS3" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VZS3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VZS3" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZU2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 500, "chemical_mass": 58106.0, "gene_names": "rasp;7F21;CG11495;Dmel\\CG11495;RASP;Rasp;Ski;cmn;cnm;l(3)63Bg;l(3)M47;l(3)SG3;l(3)m47;rasp;rsp;sig/ski;sit;ski/sit;ski", "protein_name": "Protein-cysteine N-palmitoyltransferase Rasp", "disease": [ { "disease_id": "DOID:0060644", "name": "chondrodysplasia-pseudohermaphroditism syndrome", "description": "A syndrome characterized by the clinical features of 46,XY complete gonadal dysgenesis in association with severe dwarfism with generalized chondrodysplasia.", "url": "https://disease-ontology.org/term/DOID:0060644", "evidence": [ { "id": "0060644", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060644" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" } ], "biological_process": [ { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "patched ligand maturation", "id": "GO:0007225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007225", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "N-terminal peptidyl-L-cysteine N-palmitoylation", "id": "GO:0018009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018009", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "epidermal growth factor receptor ligand maturation", "id": "GO:0038004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038004", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "segment polarity determination", "id": "GO:0007367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007367", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "dorsal appendage formation", "id": "GO:0046843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046843", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "wing disc anterior/posterior pattern formation", "id": "GO:0048100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048100", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "acyltransferase activity", "id": "GO:0016746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016746", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" }, { "name": "palmitoyltransferase activity", "id": "GO:0016409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016409", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU2", "url": "https://www.uniprot.org/uniprotkb/Q9VZU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZV5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZV5", "url": "https://www.uniprot.org/uniprotkb/Q9VZV5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 412, "chemical_mass": 45395.0, "gene_names": "CG14954;CG16745;CG32486;Dmel\\CG32486;anon-WO0118547.267;l(2)SH3 095;l(3)SH095", "protein_name": "Zinc finger TRAF-type-containing protein 1 homolog", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV5", "url": "https://www.uniprot.org/uniprotkb/Q9VZV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9VZZ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 878, "chemical_mass": 95536.0, "gene_names": "dos;141511_at;CG1044;DOS;Dmel\\CG1044;Dos;E(csw)3A;E(csw[CS])3A;EC3-4;Gab-1;Su(sev)3A;Su(sev[S11])3A;dos", "protein_name": "Protein daughter of sevenless", "disease": [ { "disease_id": "DOID:0110484", "name": "autosomal recessive nonsyndromic deafness 26", "description": "An autosomal recessive nonsyndromic deafness that has_material_basis_in homozygous mutation in the GAB1 gene on chromosome 4q31.", "url": "https://disease-ontology.org/term/DOID:0110484", "evidence": [ { "id": "0110484", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110484" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" }, { "name": "photoreceptor cell development", "id": "GO:0042461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042461", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" }, { "name": "regulation of Ras protein signal transduction", "id": "GO:0046578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046578", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" }, { "name": "anterior/posterior axis specification, embryo", "id": "GO:0008595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008595", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" }, { "name": "R7 cell fate commitment", "id": "GO:0007465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007465", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" }, { "name": "torso signaling pathway", "id": "GO:0008293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008293", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" }, { "name": "sevenless signaling pathway", "id": "GO:0045500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045500", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZZ9-1", "start_pos": "399", "end_pos": "399", "site_lbl": "Ser399", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9VZZ9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VZZ9" } ] } ] }, { "uniprot_canonical_ac": "Q9VZZ9-1", "start_pos": "481", "end_pos": "481", "site_lbl": "Thr481", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VZZ9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VZZ9" } ] } ] }, { "uniprot_canonical_ac": "Q9VZZ9-1", "start_pos": "771", "end_pos": "771", "site_lbl": "Thr771", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VZZ9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VZZ9" } ] } ] }, { "uniprot_canonical_ac": "Q9VZZ9-1", "start_pos": "801", "end_pos": "801", "site_lbl": "Tyr801", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "10601017", "url": "https://glygen.org/publication/PubMed/10601017" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9VZZ9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VZZ9" } ] } ], "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Abolishes function in photoreceptor cell development.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "10640704", "url": "https://glygen.org/publication/PubMed/10640704" } ] } ] }, { "uniprot_canonical_ac": "Q9VZZ9-1", "start_pos": "854", "end_pos": "854", "site_lbl": "Tyr854", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "10601017", "url": "https://glygen.org/publication/PubMed/10601017" }, { "database": "iPTMnet", "id": "Q9VZZ9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9VZZ9" } ] } ] }, { "uniprot_canonical_ac": "Q9VZZ9-1", "start_pos": "104", "end_pos": "104", "site_lbl": "Trp104", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Abolishes function in photoreceptor cell development.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "10640704", "url": "https://glygen.org/publication/PubMed/10640704" } ] } ] }, { "uniprot_canonical_ac": "Q9VZZ9-1", "start_pos": "644", "end_pos": "644", "site_lbl": "Arg644", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "K", "comment": "Impairs interaction with DRK.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "12128212", "url": "https://glygen.org/publication/PubMed/12128212" } ] } ] }, { "uniprot_canonical_ac": "Q9VZZ9-1", "start_pos": "696", "end_pos": "696", "site_lbl": "Arg696", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "K", "comment": "Impairs interaction with DRK.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ9" }, { "database": "PubMed", "id": "12128212", "url": "https://glygen.org/publication/PubMed/12128212" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W011-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W011", "url": "https://www.uniprot.org/uniprotkb/Q9W011" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 510, "chemical_mass": 58213.0, "gene_names": "Cyp4d20;4d20;CG16761;CYP4d20;Cyp4d20;Dmel\\CG16761;RH59895", "protein_name": "Probable cytochrome P450 4d20", "disease": [ { "disease_id": "DOID:0050664", "name": "Bietti crystalline corneoretinal dystrophy", "description": "A retinal degeneration that is characterized by crystals in the cornea, shiny deposits on the retina and progressive atrophy of the retina, choriocapillaris and choroid, has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the CYP4V2 gene on chromosome 4q35.", "url": "https://disease-ontology.org/term/DOID:0050664", "evidence": [ { "id": "0050664", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050664" } ], "weight": 0.0 }, { "disease_id": "DOID:0110861", "name": "autosomal recessive polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion.", "url": "https://disease-ontology.org/term/DOID:0110861", "evidence": [ { "id": "0110861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110861" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9W011", "url": "https://www.uniprot.org/uniprotkb/Q9W011" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9W011", "url": "https://www.uniprot.org/uniprotkb/Q9W011" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9W011", "url": "https://www.uniprot.org/uniprotkb/Q9W011" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9W011", "url": "https://www.uniprot.org/uniprotkb/Q9W011" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W011", "url": "https://www.uniprot.org/uniprotkb/Q9W011" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W056-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 451, "chemical_mass": 50042.0, "gene_names": "acs;CG1139;Dmel\\CG1139;acs", "protein_name": "Proton-coupled amino acid transporter-like protein acs", "disease": [ { "disease_id": "DOID:0112265", "name": "iminoglycinuria", "description": "A renal tubular transport disease characterized by impaired renal tube reabsorption of proline, hydroxyproline and glycine and elevated urine levels of the imino acids and glycine that has_material_basis_in homozygous mutation in SLC36A2 on chromosome 5q33.1 combined with either heterozygous mutation in SLC6A20 gene on chromosome 3p21.31 or homozygous mutation in SLC6A19 on chromosome 5p15.33.", "url": "https://disease-ontology.org/term/DOID:0112265", "evidence": [ { "id": "0112265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112265" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" }, { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" }, { "name": "basal plasma membrane", "id": "GO:0009925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009925", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" }, { "name": "basal labyrinth", "id": "GO:0033774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033774", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of growth", "id": "GO:0040008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040008", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "Q9W056", "url": "https://www.uniprot.org/uniprotkb/Q9W056" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W056-1", "start_pos": "299", "end_pos": "299", "site_lbl": "Asn299", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 299, "start_aa": "Asn", "end_pos": 299, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn299", "evidence": [ { "id": "Q9W056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W056#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W056-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Asn75", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 75, "start_aa": "Asn", "end_pos": 75, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn75", "evidence": [ { "id": "Q9W056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W056#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W088-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 431, "chemical_mass": 48009.0, "gene_names": "PolD2;12018;BcDNA:HL03874;CG12018;DNApolD1;Dmel\\CG12018;Pol31;PolD2", "protein_name": "DNA polymerase delta subunit 2", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA strand elongation involved in DNA replication", "id": "GO:0006271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006271", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" }, { "name": "mitotic DNA-templated DNA replication", "id": "GO:1990506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990506", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" } ], "cellular_component": [ { "name": "delta DNA polymerase complex", "id": "GO:0043625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043625", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" }, { "name": "zeta DNA polymerase complex", "id": "GO:0016035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016035", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9W088", "url": "https://www.uniprot.org/uniprotkb/Q9W088" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W092-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 484, "chemical_mass": 54122.0, "gene_names": "Cht2;CG2054;CHT2;Cht-2;Cht2;Cht;DmCHT2;DmCht2;Dmel\\CG2054;cht2", "protein_name": "Probable chitinase 2", "disease": [ { "disease_id": "DOID:0050073", "name": "invasive aspergillosis", "description": "An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage.", "url": "https://disease-ontology.org/term/DOID:0050073", "evidence": [ { "id": "0050073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050073" } ], "weight": 0.0 }, { "disease_id": "DOID:0050127", "name": "sinusitis", "description": "A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip.", "url": "https://disease-ontology.org/term/DOID:0050127", "evidence": [ { "id": "0050127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050127" } ], "weight": 0.0 }, { "disease_id": "DOID:10325", "name": "silicosis", "description": "A pneumoconiosis that is an inflammation and scarring of the upper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles.", "url": "https://disease-ontology.org/term/DOID:10325", "evidence": [ { "id": "10325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10325" } ], "weight": 0.0 }, { "disease_id": "DOID:12053", "name": "cryptococcosis", "description": "An opportunistic mycosis that results_in fungal infection and has_material_basis_in Cryptococcus neoformans or Cryptococcus gattii.", "url": "https://disease-ontology.org/term/DOID:12053", "evidence": [ { "id": "12053", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12053" } ], "weight": 0.0 }, { "disease_id": "DOID:2378", "name": "relapsing-remitting multiple sclerosis", "description": "A multiple sclerosis that is characterized by relapse (attacks of symptom flare-ups) followed by remission (periods of recovery). Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles.", "url": "https://disease-ontology.org/term/DOID:2378", "evidence": [ { "id": "2378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2378" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:8869", "name": "neuromyelitis optica", "description": "A central nervous system disease characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis).", "url": "https://disease-ontology.org/term/DOID:8869", "evidence": [ { "id": "8869", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8869" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "external side of apical plasma membrane", "id": "GO:0098591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098591", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" } ], "biological_process": [ { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "polysaccharide catabolic process", "id": "GO:0000272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000272", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "chitin catabolic process", "id": "GO:0006032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006032", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "chitin-based embryonic cuticle biosynthetic process", "id": "GO:0008362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008362", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "larval chitin-based cuticle development", "id": "GO:0008363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008363", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "ecdysis, chitin-based cuticle", "id": "GO:0018990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018990", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "regulation of tube size, open tracheal system", "id": "GO:0035151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035151", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitinase activity", "id": "GO:0004568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004568", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "endochitinase activity", "id": "GO:0008843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008843", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W092-1", "start_pos": "467", "end_pos": "467", "site_lbl": "Ser467", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W092", "url": "https://www.uniprot.org/uniprotkb/Q9W092" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W092", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W092" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W0Z5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W0Z5", "url": "https://www.uniprot.org/uniprotkb/Q9W0Z5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 536, "chemical_mass": 58337.0, "gene_names": "Atf-2;Atf-2;CG30420;CG3749;CG44247;Dmel\\CG44247;Dmel_CG44247;FBgn0050420", "protein_name": "Neural proliferation differentiation and control protein 1", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W0Z5", "url": "https://www.uniprot.org/uniprotkb/Q9W0Z5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W0Z5-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Thr343", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 343, "start_aa": "Thr", "end_pos": 343, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr343", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W0Z5-1", "start_pos": "458", "end_pos": "458", "site_lbl": "Thr458", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 458, "start_aa": "Thr", "end_pos": 458, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr458", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W130-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W130", "url": "https://www.uniprot.org/uniprotkb/Q9W130" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 522, "chemical_mass": 60538.0, "gene_names": "Cyp9c1;9c1;CG3616;CYP9C1;Cyp9C1;Cyp9c1;Dmel\\CG3616;P-450;P450", "protein_name": "Cytochrome P450 9c1", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0060903", "name": "thrombosis", "description": "A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.", "url": "https://disease-ontology.org/term/DOID:0060903", "evidence": [ { "id": "0060903", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060903" } ], "weight": 0.0 }, { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:0080630", "name": "B-lymphoblastic leukemia/lymphoma", "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow.", "url": "https://disease-ontology.org/term/DOID:0080630", "evidence": [ { "id": "0080630", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080630" } ], "weight": 0.0 }, { "disease_id": "DOID:0080998", "name": "acute necrotizing pancreatitis", "description": "An acute pancreatitis that is characterized by one or more areas of necrosis in the pancreas with varying degree of involvement of the surrounding tissues or organ systems.", "url": "https://disease-ontology.org/term/DOID:0080998", "evidence": [ { "id": "0080998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080998" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10825", "name": "essential hypertension", "description": "A hypertension with no known cause. It is the most common type of hypertension.", "url": "https://disease-ontology.org/term/DOID:10825", "evidence": [ { "id": "10825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10825" } ], "weight": 0.0 }, { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:11111", "name": "hydronephrosis", "description": "An urinary system disease that is characterized by swelling of one or both kidneys due to incomplete voiding of urine.", "url": "https://disease-ontology.org/term/DOID:11111", "evidence": [ { "id": "11111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11111" } ], "weight": 0.0 }, { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5773", "name": "oral submucous fibrosis", "description": "A mouth disease that is characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues.", "url": "https://disease-ontology.org/term/DOID:5773", "evidence": [ { "id": "5773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5773" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9477", "name": "pulmonary embolism", "description": "An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot.", "url": "https://disease-ontology.org/term/DOID:9477", "evidence": [ { "id": "9477", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9477" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9W130", "url": "https://www.uniprot.org/uniprotkb/Q9W130" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9W130", "url": "https://www.uniprot.org/uniprotkb/Q9W130" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9W130", "url": "https://www.uniprot.org/uniprotkb/Q9W130" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9W130", "url": "https://www.uniprot.org/uniprotkb/Q9W130" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W130", "url": "https://www.uniprot.org/uniprotkb/Q9W130" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W133-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W133", "url": "https://www.uniprot.org/uniprotkb/Q9W133" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 518, "chemical_mass": 59859.0, "gene_names": "Adck1;ADCK1;Adck1;Adck;CG3608;Dmel\\CG3608;cg3608;dADCK1", "protein_name": "AarF domain-containing kinase 1", "disease": [], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q9W133", "url": "https://www.uniprot.org/uniprotkb/Q9W133" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9W133", "url": "https://www.uniprot.org/uniprotkb/Q9W133" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9W133", "url": "https://www.uniprot.org/uniprotkb/Q9W133" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "Q9W133", "url": "https://www.uniprot.org/uniprotkb/Q9W133" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "Q9W133", "url": "https://www.uniprot.org/uniprotkb/Q9W133" } ], "pmid": "" }, { "name": "positive regulation of cristae formation", "id": "GO:1903852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903852", "evidence": [ { "database": "UniProtKB", "id": "Q9W133", "url": "https://www.uniprot.org/uniprotkb/Q9W133" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial fusion", "id": "GO:0010637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010637", "evidence": [ { "database": "UniProtKB", "id": "Q9W133", "url": "https://www.uniprot.org/uniprotkb/Q9W133" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1B0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1637, "chemical_mass": 186724.0, "gene_names": "gek;CG4012;Dmel\\CG4012;Gek;MRCKalpha;MRCK;MdaPk;Mrck;anon-WO0200864.1;dMRCK;gek;l(2)09373", "protein_name": "Serine/threonine-protein kinase Genghis Khan", "disease": [ { "disease_id": "DOID:0060669", "name": "cerebral cavernous malformation", "description": "A cerebrovascular disease that is characterized by dilated blood-filled capillaries lacking structural support.", "url": "https://disease-ontology.org/term/DOID:0060669", "evidence": [ { "id": "0060669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060669" } ], "weight": 0.0 }, { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" } ], "biological_process": [ { "name": "actin polymerization or depolymerization", "id": "GO:0008154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008154", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" }, { "name": "synaptic target recognition", "id": "GO:0008039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008039", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W1B0-1", "start_pos": "1584", "end_pos": "1584", "site_lbl": "Ser1584", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9W1B0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1B0" } ] } ] }, { "uniprot_canonical_ac": "Q9W1B0-1", "start_pos": "895", "end_pos": "895", "site_lbl": "Thr895", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1B0", "url": "https://www.uniprot.org/uniprotkb/Q9W1B0" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W1B0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1B0" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1H4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 747, "chemical_mass": 84719.0, "gene_names": "DNAlig1;CG5602;DNA-lig1;DNA-ligI;DNAlig1;Dlig-I;DmDNA Lig I;Dmel\\CG5602;LIG1;dDNAlig1", "protein_name": "DNA ligase 1", "disease": [ { "disease_id": "DOID:0061066", "name": "immunodeficiency 96", "description": "A primary immunodeficiency disease that is characterized by onset of recurrent, usually viral, respiratory infections in infancy or early childhood and that has_material_basis_in homozygous or compound heterozygous mutation in the LIG1 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0061066", "evidence": [ { "id": "0061066", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061066" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:612", "name": "primary immunodeficiency disease", "description": "An immune system disease that results when one or more essential parts of the immune system is missing or not working properly at birth due to a genetic mutation.", "url": "https://disease-ontology.org/term/DOID:612", "evidence": [ { "id": "612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:612" } ], "weight": 0.0 }, { "disease_id": "DOID:655", "name": "inherited metabolic disorder", "description": "A disease of metabolism that is characterized by enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to inherited enzyme abnormality.", "url": "https://disease-ontology.org/term/DOID:655", "evidence": [ { "id": "655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:655" } ], "weight": 0.0 }, { "disease_id": "DOID:7725", "name": "epilepsy with generalized tonic-clonic seizures", "description": "An adolescence-adult electroclinical syndrome starting in adolescence exhibiting generalized tonic-clonic seizures as the only seizure type.", "url": "https://disease-ontology.org/term/DOID:7725", "evidence": [ { "id": "7725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7725" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA biosynthetic process", "id": "GO:0071897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071897", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" }, { "name": "lagging strand elongation", "id": "GO:0006273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006273", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" }, { "name": "Okazaki fragment processing involved in mitotic DNA replication", "id": "GO:1903461", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903461", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" }, { "name": "DNA ligase (ATP) activity", "id": "GO:0003910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003910", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W1H4-1", "start_pos": "18", "end_pos": "18", "site_lbl": "Ser18", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W1H4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1H4" } ] } ] }, { "uniprot_canonical_ac": "Q9W1H4-1", "start_pos": "20", "end_pos": "20", "site_lbl": "Ser20", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W1H4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1H4" } ] } ] }, { "uniprot_canonical_ac": "Q9W1H4-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Ser42", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W1H4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1H4" } ] } ] }, { "uniprot_canonical_ac": "Q9W1H4-1", "start_pos": "44", "end_pos": "44", "site_lbl": "Ser44", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W1H4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1H4" } ] } ] }, { "uniprot_canonical_ac": "Q9W1H4-1", "start_pos": "46", "end_pos": "46", "site_lbl": "Ser46", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W1H4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1H4" } ] } ] }, { "uniprot_canonical_ac": "Q9W1H4-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W1H4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1H4" } ] } ] }, { "uniprot_canonical_ac": "Q9W1H4-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Ser65", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H4", "url": "https://www.uniprot.org/uniprotkb/Q9W1H4" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9W1H4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W1H4" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1I9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 455, "chemical_mass": 51838.0, "gene_names": "shu;CG4735;Dmel\\CG4735;Shu;shu", "protein_name": "Inactive peptidyl-prolyl cis-trans isomerase shutdown", "disease": [ { "disease_id": "DOID:0070576", "name": "spermatogenic failure 77", "description": "A spermatogenic failure characterized by extreme oligozoospermia or azoospermia that has_material_basis_in homozygous or compound heterozygous mutation in the FKBP6 gene on chromosome 7q11.23.", "url": "https://disease-ontology.org/term/DOID:0070576", "evidence": [ { "id": "0070576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070576" } ], "weight": 0.0 }, { "disease_id": "DOID:12336", "name": "male infertility", "description": "", "url": "https://disease-ontology.org/term/DOID:12336", "evidence": [ { "id": "12336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12336" } ], "weight": 0.0 }, { "disease_id": "DOID:1928", "name": "Williams-Beuren syndrome", "description": "A syndrome that is characterized by mild to moderate intellectual disability, a broad forehead, a short nose with a broad tip, full cheeks, and a wide mouth with full lips and difficulty with visual-spatial tasks and has_material_basis_in hemizygous deletion of 1.5 to 1.8 Mb on chromosome 7q11.23.", "url": "https://disease-ontology.org/term/DOID:1928", "evidence": [ { "id": "1928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1928" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "P granule", "id": "GO:0043186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043186", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "Yb body", "id": "GO:0070725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070725", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "piRNA processing", "id": "GO:0034587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034587", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "transposable element silencing", "id": "GO:0010526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010526", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "primary piRNA processing", "id": "GO:0140990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140990", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "secondary piRNA processing", "id": "GO:0140965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140965", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" } ], "molecular_function": [ { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W1I9-1", "start_pos": "335", "end_pos": "335", "site_lbl": "Ala335", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "T", "comment": "In PB70; weak allele that only affects female fertility without affecting male fertility.", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I9", "url": "https://www.uniprot.org/uniprotkb/Q9W1I9" }, { "database": "PubMed", "id": "10978289", "url": "https://glygen.org/publication/PubMed/10978289" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1N5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 406, "chemical_mass": 47559.0, "gene_names": "Gr59f;59E.1;CG33150;CG5365;Dmel\\CG33150;GR59E.1;GR59f;Gr59E1;Gr59f", "protein_name": "Putative gustatory receptor 59f", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of taste", "id": "GO:0050912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050912", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N5", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W1N5-1", "start_pos": "147", "end_pos": "147", "site_lbl": "Asn147", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 147, "start_aa": "Asn", "end_pos": 147, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn147", "evidence": [ { "id": "Q9W1N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9W1N5-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Asn254", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 254, "start_aa": "Asn", "end_pos": 254, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn254", "evidence": [ { "id": "Q9W1N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9W1N5-1", "start_pos": "401", "end_pos": "401", "site_lbl": "Asn401", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 401, "start_aa": "Asn", "end_pos": 401, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn401", "evidence": [ { "id": "Q9W1N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1N5#ptm_processing" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1U4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 626, "chemical_mass": 70053.0, "gene_names": "Klp59C;CG3219;DmCG3219;DmKLP59C;DmKlp59C;Dmel\\CG3219;KIF 2B;KIF2A/B/C;KLP59C;Klp59C", "protein_name": "Kinesin-like protein Klp59C", "disease": [ { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "kinetochore microtubule", "id": "GO:0005828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005828", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" } ], "biological_process": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U4", "url": "https://www.uniprot.org/uniprotkb/Q9W1U4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1V1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1V1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 690, "chemical_mass": 77946.0, "gene_names": "Art7;Art7;CG9882;DART7;Dmel\\CG9882;PRMT7;dart7", "protein_name": "Protein arginine N-methyltransferase 7", "disease": [], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V1" } ], "pmid": "" }, { "name": "peptidyl-arginine methylation", "id": "GO:0018216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018216", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-arginine N-methyltransferase activity", "id": "GO:0016274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016274", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V1" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V1" } ], "pmid": "" }, { "name": "protein-arginine omega-N symmetric methyltransferase activity", "id": "GO:0035243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035243", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1V3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 344, "chemical_mass": 34637.0, "gene_names": "Fib;CG9888;Dmel\\CG9888;Fibri;Fib;GCR-6;GCR6;Pen59C5;dFib;fibrillarin;fib;pen59C5", "protein_name": "rRNA 2'-O-methyltransferase fibrillarin", "disease": [], "biological_process": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "box C/D sno(s)RNA 3'-end processing", "id": "GO:0000494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000494", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "rRNA 2'-O-methylation", "id": "GO:0000451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000451", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "snoRNA guided rRNA 2'-O-methylation", "id": "GO:0000452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000452", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "rRNA methyltransferase activity", "id": "GO:0008649", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008649", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "histone H2AQ104 methyltransferase activity", "id": "GO:1990259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990259", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "dense fibrillar component", "id": "GO:0001651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001651", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "box C/D methylation guide snoRNP complex", "id": "GO:0031428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031428", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V3", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1X8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1X8", "url": "https://www.uniprot.org/uniprotkb/Q9W1X8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 321, "chemical_mass": 36123.0, "gene_names": "Gmer;CG3495;DmGMER;Dmel\\CG3495;GER;Gmer;gmer;l(2)SH1931", "protein_name": "Probable GDP-L-fucose synthase", "disease": [], "biological_process": [ { "name": "'de novo' GDP-L-fucose biosynthetic process", "id": "GO:0042351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042351", "evidence": [ { "database": "UniProtKB", "id": "Q9W1X8", "url": "https://www.uniprot.org/uniprotkb/Q9W1X8" } ], "pmid": "" } ], "molecular_function": [ { "name": "GDP-L-fucose synthase activity", "id": "GO:0050577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050577", "evidence": [ { "database": "UniProtKB", "id": "Q9W1X8", "url": "https://www.uniprot.org/uniprotkb/Q9W1X8" } ], "pmid": "" }, { "name": "GDP-mannose 3,5-epimerase activity", "id": "GO:0047918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047918", "evidence": [ { "database": "UniProtKB", "id": "Q9W1X8", "url": "https://www.uniprot.org/uniprotkb/Q9W1X8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W1X8", "url": "https://www.uniprot.org/uniprotkb/Q9W1X8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W1Y1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 203, "chemical_mass": 22781.0, "gene_names": "EMC8-9;BcDNA:SD01117;CG3501;Dmel\\CG3501;EMC8-9;EMC8/9;emc8/9", "protein_name": "ER membrane protein complex subunit 8/9 homolog", "disease": [], "cellular_component": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y1" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y1" } ], "pmid": "" } ], "biological_process": [ { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y1" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W223-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W223", "url": "https://www.uniprot.org/uniprotkb/Q9W223" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 512, "chemical_mass": 58679.0, "gene_names": "Cyp6d2;6d2;CG4373;Cyp6d2;Dmel\\CG4373", "protein_name": "Probable cytochrome P450 6d2", "disease": [ { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:0080630", "name": "B-lymphoblastic leukemia/lymphoma", "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow.", "url": "https://disease-ontology.org/term/DOID:0080630", "evidence": [ { "id": "0080630", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080630" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10825", "name": "essential hypertension", "description": "A hypertension with no known cause. It is the most common type of hypertension.", "url": "https://disease-ontology.org/term/DOID:10825", "evidence": [ { "id": "10825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10825" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:5773", "name": "oral submucous fibrosis", "description": "A mouth disease that is characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues.", "url": "https://disease-ontology.org/term/DOID:5773", "evidence": [ { "id": "5773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5773" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9W223", "url": "https://www.uniprot.org/uniprotkb/Q9W223" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9W223", "url": "https://www.uniprot.org/uniprotkb/Q9W223" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9W223", "url": "https://www.uniprot.org/uniprotkb/Q9W223" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "Q9W223", "url": "https://www.uniprot.org/uniprotkb/Q9W223" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W223", "url": "https://www.uniprot.org/uniprotkb/Q9W223" } ], "pmid": "" } ], "biological_process": [ { "name": "response to camptothecin", "id": "GO:1901563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901563", "evidence": [ { "database": "UniProtKB", "id": "Q9W223", "url": "https://www.uniprot.org/uniprotkb/Q9W223" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W256-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W256", "url": "https://www.uniprot.org/uniprotkb/Q9W256" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 155, "chemical_mass": 17370.0, "gene_names": "PolE4;11301;BcDNA:GM21739;CG11301;DNApolE4;Dmel\\CG11301;MES4;Mes4;NF-Yc;PolE4", "protein_name": "DNA polymerase epsilon subunit 4", "disease": [], "cellular_component": [ { "name": "epsilon DNA polymerase complex", "id": "GO:0008622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008622", "evidence": [ { "database": "UniProtKB", "id": "Q9W256", "url": "https://www.uniprot.org/uniprotkb/Q9W256" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W256", "url": "https://www.uniprot.org/uniprotkb/Q9W256" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q9W256", "url": "https://www.uniprot.org/uniprotkb/Q9W256" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q9W256", "url": "https://www.uniprot.org/uniprotkb/Q9W256" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W2P0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 565, "chemical_mass": 65823.0, "gene_names": "dgt3;CG3221;Dgt3;Dmel\\CG3221;dgt3;dim", "protein_name": "Augmin complex subunit dgt3", "disease": [], "biological_process": [ { "name": "regulation of microtubule nucleation", "id": "GO:0010968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010968", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "mitotic spindle-templated microtubule nucleation", "id": "GO:0090221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090221", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" }, { "name": "HAUS complex", "id": "GO:0070652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070652", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P0", "url": "https://www.uniprot.org/uniprotkb/Q9W2P0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W332-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3750, "chemical_mass": 418179.0, "gene_names": "Cubn;CG2996;CG32702;CT7882;Cubn;Dmel\\CG32702;cubilin;dCubn;tok-like", "protein_name": "Cubilin homolog", "disease": [ { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney.", "url": "https://disease-ontology.org/term/DOID:557", "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ], "weight": 0.0 } ], "biological_process": [ { "name": "renal protein absorption", "id": "GO:0097017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097017", "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "pmid": "" }, { "name": "nephrocyte filtration", "id": "GO:0097206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097206", "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "pmid": "" }, { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "Q9W332", "url": "https://www.uniprot.org/uniprotkb/Q9W332" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1119", "end_pos": "1119", "site_lbl": "Asn1119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1119, "start_aa": "Asn", "end_pos": 1119, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1119", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1152", "end_pos": "1152", "site_lbl": "Asn1152", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1152, "start_aa": "Asn", "end_pos": 1152, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1152", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "123", "end_pos": "123", "site_lbl": "Asn123", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 123, "start_aa": "Asn", "end_pos": 123, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn123", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1335", "end_pos": "1335", "site_lbl": "Asn1335", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1335, "start_aa": "Asn", "end_pos": 1335, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1335", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1359", "end_pos": "1359", "site_lbl": "Asn1359", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1359, "start_aa": "Asn", "end_pos": 1359, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1359", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1413", "end_pos": "1413", "site_lbl": "Asn1413", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1413, "start_aa": "Asn", "end_pos": 1413, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1413", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1424", "end_pos": "1424", "site_lbl": "Asn1424", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1424, "start_aa": "Asn", "end_pos": 1424, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1424", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1491", "end_pos": "1491", "site_lbl": "Asn1491", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1491, "start_aa": "Asn", "end_pos": 1491, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1491", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1694", "end_pos": "1694", "site_lbl": "Asn1694", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1694, "start_aa": "Asn", "end_pos": 1694, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1694", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "1908", "end_pos": "1908", "site_lbl": "Asn1908", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1908, "start_aa": "Asn", "end_pos": 1908, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1908", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2009", "end_pos": "2009", "site_lbl": "Asn2009", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2009, "start_aa": "Asn", "end_pos": 2009, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2009", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2092", "end_pos": "2092", "site_lbl": "Asn2092", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2092, "start_aa": "Asn", "end_pos": 2092, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2092", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2128", "end_pos": "2128", "site_lbl": "Asn2128", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2128, "start_aa": "Asn", "end_pos": 2128, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2128", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2152", "end_pos": "2152", "site_lbl": "Asn2152", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2152, "start_aa": "Asn", "end_pos": 2152, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2152", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2231", "end_pos": "2231", "site_lbl": "Asn2231", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2231, "start_aa": "Asn", "end_pos": 2231, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2231", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2377", "end_pos": "2377", "site_lbl": "Asn2377", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2377, "start_aa": "Asn", "end_pos": 2377, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2377", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2442", "end_pos": "2442", "site_lbl": "Asn2442", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2442, "start_aa": "Asn", "end_pos": 2442, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2442", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2655", "end_pos": "2655", "site_lbl": "Asn2655", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2655, "start_aa": "Asn", "end_pos": 2655, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2655", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2671", "end_pos": "2671", "site_lbl": "Asn2671", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2671, "start_aa": "Asn", "end_pos": 2671, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2671", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2682", "end_pos": "2682", "site_lbl": "Asn2682", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2682, "start_aa": "Asn", "end_pos": 2682, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2682", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2772", "end_pos": "2772", "site_lbl": "Asn2772", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2772, "start_aa": "Asn", "end_pos": 2772, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2772", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2885", "end_pos": "2885", "site_lbl": "Asn2885", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2885, "start_aa": "Asn", "end_pos": 2885, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2885", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2889", "end_pos": "2889", "site_lbl": "Asn2889", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2889, "start_aa": "Asn", "end_pos": 2889, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2889", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2960", "end_pos": "2960", "site_lbl": "Asn2960", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2960, "start_aa": "Asn", "end_pos": 2960, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2960", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2965", "end_pos": "2965", "site_lbl": "Asn2965", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2965, "start_aa": "Asn", "end_pos": 2965, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2965", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "2982", "end_pos": "2982", "site_lbl": "Asn2982", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 2982, "start_aa": "Asn", "end_pos": 2982, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2982", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "3040", "end_pos": "3040", "site_lbl": "Asn3040", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3040, "start_aa": "Asn", "end_pos": 3040, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3040", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "3074", "end_pos": "3074", "site_lbl": "Asn3074", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3074, "start_aa": "Asn", "end_pos": 3074, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3074", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "3160", "end_pos": "3160", "site_lbl": "Asn3160", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3160, "start_aa": "Asn", "end_pos": 3160, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3160", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "3256", "end_pos": "3256", "site_lbl": "Asn3256", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3256, "start_aa": "Asn", "end_pos": 3256, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3256", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "3427", "end_pos": "3427", "site_lbl": "Asn3427", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3427, "start_aa": "Asn", "end_pos": 3427, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3427", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "3543", "end_pos": "3543", "site_lbl": "Asn3543", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3543, "start_aa": "Asn", "end_pos": 3543, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3543", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "3572", "end_pos": "3572", "site_lbl": "Asn3572", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3572, "start_aa": "Asn", "end_pos": 3572, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3572", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "3645", "end_pos": "3645", "site_lbl": "Asn3645", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 3645, "start_aa": "Asn", "end_pos": 3645, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3645", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "424", "end_pos": "424", "site_lbl": "Asn424", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 424, "start_aa": "Asn", "end_pos": 424, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn424", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "448", "end_pos": "448", "site_lbl": "Asn448", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 448, "start_aa": "Asn", "end_pos": 448, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn448", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "51", "end_pos": "51", "site_lbl": "Asn51", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 51, "start_aa": "Asn", "end_pos": 51, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn51", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "542", "end_pos": "542", "site_lbl": "Asn542", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 542, "start_aa": "Asn", "end_pos": 542, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn542", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "548", "end_pos": "548", "site_lbl": "Asn548", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 548, "start_aa": "Asn", "end_pos": 548, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn548", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Asn609", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 609, "start_aa": "Asn", "end_pos": 609, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn609", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9W332-1", "start_pos": "871", "end_pos": "871", "site_lbl": "Asn871", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 871, "start_aa": "Asn", "end_pos": 871, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn871", "evidence": [ { "id": "Q9W332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W332#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W351-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 466, "chemical_mass": 52279.0, "gene_names": "Aladin;ALADIN;Aladin;CG16892;Dmel\\CG16892;aladin", "protein_name": "Aladin", "disease": [ { "disease_id": "DOID:0050602", "name": "triple-A syndrome", "description": "A syndrome characterized by achalasia, adrenal insufficiency and alacrima and has_material_basis_in mutations in the AAAS gene that encodes ALADIN within the nuclear envelope and results in dysfunction of the autonomic nervous system.", "url": "https://disease-ontology.org/term/DOID:0050602", "evidence": [ { "id": "0050602", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050602" } ], "weight": 0.0 }, { "disease_id": "DOID:9164", "name": "achalasia", "description": "An esophageal disease that is characterized by an inability of the esophagus to move food toward the stomach resulting from the lower esophogeal sphincter not fully relaxing during swallowing.", "url": "https://disease-ontology.org/term/DOID:9164", "evidence": [ { "id": "9164", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9164" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of protein localization to spindle pole body", "id": "GO:1902365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902365", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "nucleocytoplasmic transport", "id": "GO:0006913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006913", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "Q9W351", "url": "https://www.uniprot.org/uniprotkb/Q9W351" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W354-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 916, "chemical_mass": 105715.0, "gene_names": "Erk7;CG17441;CG2309;CG32703;Dmel\\CG32703;ERK7;ERK;Erk7;Erk;erk", "protein_name": "Extracellular signal-regulated kinase 7", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of protein secretion", "id": "GO:0050709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050709", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "negative regulation of cell size", "id": "GO:0045792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045792", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "ciliary transition zone assembly", "id": "GO:1905349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905349", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "MAP kinase activity", "id": "GO:0004707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004707", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W354-1", "start_pos": "373", "end_pos": "373", "site_lbl": "Thr373", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 373, "start_aa": "Thr", "end_pos": 373, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr373", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W354-1", "start_pos": "190", "end_pos": "190", "site_lbl": "Thr190", "weight": 0.0, "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Does not lead to transitional endoplasmic reticulum sites disassembly; when associated with F-192.", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" }, { "database": "PubMed", "id": "21847093", "url": "https://glygen.org/publication/PubMed/21847093" } ] } ] }, { "uniprot_canonical_ac": "Q9W354-1", "start_pos": "192", "end_pos": "192", "site_lbl": "Tyr192", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Does not lead to transitional endoplasmic reticulum sites disassembly; when associated with A-190.", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" }, { "database": "PubMed", "id": "21847093", "url": "https://glygen.org/publication/PubMed/21847093" } ] } ] }, { "uniprot_canonical_ac": "Q9W354-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Lys54", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Does not lead to transitional endoplasmic reticulum sites disassembly. Partially rescue transitional endoplasmic reticulum site disassembly induced by amino-acid starvation.", "evidence": [ { "database": "UniProtKB", "id": "Q9W354", "url": "https://www.uniprot.org/uniprotkb/Q9W354" }, { "database": "PubMed", "id": "21847093", "url": "https://glygen.org/publication/PubMed/21847093" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W396-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 240, "chemical_mass": 25974.0, "gene_names": "HP1b;CG7041;Dmel\\CG7041;Dmel_CG7041;HP1B;HP1b;HP1;Hp1b;hp1b", "protein_name": "", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "pmid": "" }, { "name": "chromocenter", "id": "GO:0010369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010369", "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "pmid": "" } ], "biological_process": [ { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "pmid": "" }, { "name": "negative regulation of heterochromatin formation", "id": "GO:0031452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031452", "evidence": [ { "database": "UniProtKB", "id": "Q9W396", "url": "https://www.uniprot.org/uniprotkb/Q9W396" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W3E1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3E1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1022, "chemical_mass": 113423.0, "gene_names": "IntS4;CG12113;Dmel\\CG12113;Int4;IntS4;l(1)G0095", "protein_name": "Integrator complex subunit 4", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E1" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E1" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E1" } ], "pmid": "" } ], "biological_process": [ { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E1" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E1" } ], "pmid": "" } ], "molecular_function": [ { "name": "inositol hexakisphosphate binding", "id": "GO:0000822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000822", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W3I9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 475, "chemical_mass": 53844.0, "gene_names": "Traf6;2;CG10961;DTRAF2;Dmel\\CG10961;Dmel_CG10961;EP325;TRAF-6;TRAF2;TRAF6;TRAF;Traf2;Traf6/2;Traf6;dTRAF2;dTRAF6;dTraf2;dTraf6;dtraf2;dtraf6;traf2;traf6", "protein_name": "", "disease": [ { "disease_id": "DOID:0060036", "name": "intrinsic cardiomyopathy", "description": "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause.", "url": "https://disease-ontology.org/term/DOID:0060036", "evidence": [ { "id": "0060036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060036" } ], "weight": 0.0 }, { "disease_id": "DOID:14793", "name": "hypohidrotic ectodermal dysplasia", "description": "An ectodermal dysplasia that is characterized by malformation of ectodermal (skin, hair, teeth and sweat glands) structures including hypotrichosis (sparseness of scalp and body hair), hypohidrosis (reduced ability to sweat), and hypodontia (congenital absence of teeth).", "url": "https://disease-ontology.org/term/DOID:14793", "evidence": [ { "id": "14793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14793" } ], "weight": 0.0 }, { "disease_id": "DOID:2600", "name": "laryngeal carcinoma", "description": "A larynx cancer that has_material_basis_in epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2600", "evidence": [ { "id": "2600", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2600" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "tumor necrosis factor receptor superfamily binding", "id": "GO:0032813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032813", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "tumor necrosis factor receptor binding", "id": "GO:0005164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005164", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "lipopolysaccharide-mediated signaling pathway", "id": "GO:0031663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031663", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "tumor necrosis factor-mediated signaling pathway", "id": "GO:0033209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033209", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:1903265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903265", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "regulation of defense response to virus", "id": "GO:0050688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050688", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "positive regulation of programmed cell death", "id": "GO:0043068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043068", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "dorsal closure", "id": "GO:0007391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007391", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "positive regulation of Toll signaling pathway", "id": "GO:0045752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045752", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "positive regulation of peptidoglycan recognition protein signaling pathway", "id": "GO:0061059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061059", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I9", "url": "https://www.uniprot.org/uniprotkb/Q9W3I9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W3I9-1", "start_pos": "56", "end_pos": "56", "site_lbl": "Thr56", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W3I9-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Thr70", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W3J8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3J8", "url": "https://www.uniprot.org/uniprotkb/Q9W3J8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 743, "chemical_mass": 88162.0, "gene_names": "CG10958;Dmel\\CG10958", "protein_name": "Dynein regulatory complex protein 1 homolog", "disease": [ { "disease_id": "DOID:0050144", "name": "Kartagener syndrome", "description": "A primary ciliary dyskinesia that is characterized by sinusitis, bronchiectasis and situs inversus with dextrocardia resulting from dysfunction of the cilia during embryologic development.", "url": "https://disease-ontology.org/term/DOID:0050144", "evidence": [ { "id": "0050144", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050144" } ], "weight": 0.0 }, { "disease_id": "DOID:0050545", "name": "visceral heterotaxy", "description": "A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.", "url": "https://disease-ontology.org/term/DOID:0050545", "evidence": [ { "id": "0050545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050545" } ], "weight": 0.0 }, { "disease_id": "DOID:0070579", "name": "spermatogenic failure 80", "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the sperm flagella, resulting in reduced or absent progressive sperm motility, that has_material_basis_in homozygous mutation in the DRC1 gene on chromosome 2p23.3.", "url": "https://disease-ontology.org/term/DOID:0070579", "evidence": [ { "id": "0070579", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070579" } ], "weight": 0.0 }, { "disease_id": "DOID:0110596", "name": "primary ciliary dyskinesia 21", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with a missing Nexin link, infantile onset of chronic sinopulmonary infections, and has_material_basis_in homozygous mutation in the DRC1 gene on chromosome 2p23.", "url": "https://disease-ontology.org/term/DOID:0110596", "evidence": [ { "id": "0110596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110596" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q9W3J8", "url": "https://www.uniprot.org/uniprotkb/Q9W3J8" } ], "pmid": "" }, { "name": "axonemal dynein complex", "id": "GO:0005858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005858", "evidence": [ { "database": "UniProtKB", "id": "Q9W3J8", "url": "https://www.uniprot.org/uniprotkb/Q9W3J8" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium-dependent cell motility", "id": "GO:0060285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060285", "evidence": [ { "database": "UniProtKB", "id": "Q9W3J8", "url": "https://www.uniprot.org/uniprotkb/Q9W3J8" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "Q9W3J8", "url": "https://www.uniprot.org/uniprotkb/Q9W3J8" } ], "pmid": "" }, { "name": "regulation of cilium movement", "id": "GO:0003352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003352", "evidence": [ { "database": "UniProtKB", "id": "Q9W3J8", "url": "https://www.uniprot.org/uniprotkb/Q9W3J8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W3L5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3L5", "url": "https://www.uniprot.org/uniprotkb/Q9W3L5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 542, "chemical_mass": 60747.0, "gene_names": "CG15333;CG18293;Dmel\\CG15333", "protein_name": "DM7 family protein CG15333", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W3Q4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3Q4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Q4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 552, "chemical_mass": 58618.0, "gene_names": "Dmel\\CG15478;CG15478;Dmel\\CG15478;Dmel_CG15478", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Q4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Q4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Q4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Q4" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Q4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Q4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Q4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Q4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W3Q4-1", "start_pos": "245", "end_pos": "245", "site_lbl": "Thr245", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 245, "start_aa": "Thr", "end_pos": 245, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr245", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W3Q4-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W3V8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3V8", "url": "https://www.uniprot.org/uniprotkb/Q9W3V8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 511, "chemical_mass": 57945.0, "gene_names": "xit;Alg8;CG4542;Dalg8;Dmel\\CG4542;Xit;dAlg8;xit", "protein_name": "Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "disease": [ { "disease_id": "DOID:0050570", "name": "congenital disorder of glycosylation type I", "description": "A congenital disorder of glycosylation characterized by under-glycosylated serum glycoproteins.", "url": "https://disease-ontology.org/term/DOID:0050570", "evidence": [ { "id": "0050570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050570" } ], "weight": 0.0 }, { "disease_id": "DOID:0060976", "name": "polycystic liver disease 3", "description": "A liver disease characterized by the development of multiple liver cysts that usually becomes apparent in adulthood that has_material_basis_in heterozygous mutation in the ALG8 gene on chromosome 11q14.", "url": "https://disease-ontology.org/term/DOID:0060976", "evidence": [ { "id": "0060976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060976" } ], "weight": 0.0 }, { "disease_id": "DOID:0080560", "name": "congenital disorder of glycosylation Ih", "description": "A congenital disorder of glycosylation I that is characterized by gastrointestinal symptoms (diarrhea, vomiting, feeding problems with failure to thrive, protein-losing enteropathy), edema and ascites (including hydrops fetalis), hepatomegaly, renal tubulopathy, coagulation anomalies due to thrombocytopenia, brain involvement (psychomotor delay, seizures, ataxia), facial dysmorphism (low-set ears and retrognathia), pes equinovarus, and muscular hypotonia and has_material_basis_in heterozygous mutation in the gene encoding dolichyl-P-glucose:Glc-1-Man-9-GlcNAc-2-PP-dolichyl-alpha-3-glucosyltransferase on chromosome 11q14.", "url": "https://disease-ontology.org/term/DOID:0080560", "evidence": [ { "id": "0080560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080560" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V8", "url": "https://www.uniprot.org/uniprotkb/Q9W3V8" } ], "pmid": "" } ], "biological_process": [ { "name": "dolichol-linked oligosaccharide biosynthetic process", "id": "GO:0006488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006488", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V8", "url": "https://www.uniprot.org/uniprotkb/Q9W3V8" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V8", "url": "https://www.uniprot.org/uniprotkb/Q9W3V8" } ], "pmid": "" } ], "molecular_function": [ { "name": "dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity", "id": "GO:0042283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042283", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V8", "url": "https://www.uniprot.org/uniprotkb/Q9W3V8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W3Y4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 977, "chemical_mass": 104466.0, "gene_names": "pigs;CG3973;Dmel\\CG3973;pigs;pig", "protein_name": "GAS2-like protein pickled eggs", "disease": [ { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of microtubule polymerization or depolymerization", "id": "GO:0031110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031110", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "actin crosslink formation", "id": "GO:0051764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051764", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "protein localization to microtubule plus-end", "id": "GO:1904825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904825", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "follicle cell of egg chamber development", "id": "GO:0030707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030707", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "follicle cell of egg chamber stalk formation", "id": "GO:0030713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030713", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q9W3Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W3Y4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W401-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W401", "url": "https://www.uniprot.org/uniprotkb/Q9W401" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 464, "chemical_mass": 51574.0, "gene_names": "Cs1;BEST:GM01832;CG 3861;CG3861;CS;Csyn;Dmel\\CG3861;Kdn;csyn;kdn;l (1) G0030;l(1)G0030;l(1)G0033;l(1)G0159", "protein_name": "Probable citrate synthase, mitochondrial", "disease": [ { "disease_id": "DOID:0050852", "name": "limb ischemia", "description": "An ischemia that is characterized by low blood supply to tissues in the limb due to interruption in the arterial blood supply.", "url": "https://disease-ontology.org/term/DOID:0050852", "evidence": [ { "id": "0050852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050852" } ], "weight": 0.0 }, { "disease_id": "DOID:0051064", "name": "left ventricular failure", "description": "A congestive heart failure that is characterized by dysfunction of the left ventricle, resulting insufficient delivery of blood to vital organs.", "url": "https://disease-ontology.org/term/DOID:0051064", "evidence": [ { "id": "0051064", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051064" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 }, { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9W401", "url": "https://www.uniprot.org/uniprotkb/Q9W401" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9W401", "url": "https://www.uniprot.org/uniprotkb/Q9W401" } ], "pmid": "" } ], "biological_process": [ { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "Q9W401", "url": "https://www.uniprot.org/uniprotkb/Q9W401" } ], "pmid": "" }, { "name": "citrate metabolic process", "id": "GO:0006101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006101", "evidence": [ { "database": "UniProtKB", "id": "Q9W401", "url": "https://www.uniprot.org/uniprotkb/Q9W401" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q9W401", "url": "https://www.uniprot.org/uniprotkb/Q9W401" } ], "pmid": "" } ], "molecular_function": [ { "name": "citrate synthase activity", "id": "GO:0036440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036440", "evidence": [ { "database": "UniProtKB", "id": "Q9W401", "url": "https://www.uniprot.org/uniprotkb/Q9W401" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W485-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1284, "chemical_mass": 137108.0, "gene_names": "IntS6;CG3125;Dmel\\CG3125;Int6;IntS6;l(1)G0060", "protein_name": "Integrator complex subunit 6", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" }, { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" } ], "biological_process": [ { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "Q9W485", "url": "https://www.uniprot.org/uniprotkb/Q9W485" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W485-1", "start_pos": "1274", "end_pos": "1274", "site_lbl": "Thr1274", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1274, "start_aa": "Thr", "end_pos": 1274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1274", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W485-1", "start_pos": "898", "end_pos": "898", "site_lbl": "Thr898", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 898, "start_aa": "Thr", "end_pos": 898, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr898", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W4M8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 188, "chemical_mass": 21425.0, "gene_names": "dgt4;BcDNA:SD26403;CG4865;Dgt4;Dmel\\CG4865;EG0007.10;EG:EG0007.10;dgt4;msd3", "protein_name": "Augmin complex subunit dgt4", "disease": [], "biological_process": [ { "name": "regulation of microtubule nucleation", "id": "GO:0010968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010968", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "mitotic spindle-templated microtubule nucleation", "id": "GO:0090221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090221", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" }, { "name": "HAUS complex", "id": "GO:0070652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070652", "evidence": [ { "database": "UniProtKB", "id": "Q9W4M8", "url": "https://www.uniprot.org/uniprotkb/Q9W4M8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W4M8-1", "start_pos": "6", "end_pos": "6", "site_lbl": "Thr6", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6, "start_aa": "Thr", "end_pos": 6, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W4S1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4S1", "url": "https://www.uniprot.org/uniprotkb/Q9W4S1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 582, "chemical_mass": 63369.0, "gene_names": "CG12206;Dmel\\CG12206", "protein_name": "Glutaredoxin domain-containing cysteine-rich protein CG12206", "disease": [ { "disease_id": "DOID:0110483", "name": "autosomal recessive nonsyndromic deafness 25", "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with moderate to profound, progressive hearing loss and has_material_basis_in mutation in the GRXCR1 gene on chromosome 4p13.", "url": "https://disease-ontology.org/term/DOID:0110483", "evidence": [ { "id": "0110483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110483" } ], "weight": 0.0 } ], "biological_process": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "Q9W4S1", "url": "https://www.uniprot.org/uniprotkb/Q9W4S1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W4X7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 269, "chemical_mass": 29946.0, "gene_names": "eIF3g1;CG8636;Dmel\\CG8636;cg8636;eIF s4;eIF-3ga;eIF-3;eIF3-S4;eIF3G1;eIF3g1;eIF3ga;eIF3g", "protein_name": "Eukaryotic translation initiation factor 3 subunit G-1", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "pmid": "" }, { "name": "formation of cytoplasmic translation initiation complex", "id": "GO:0001732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001732", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "pmid": "" } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 3 complex", "id": "GO:0005852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005852", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W4X7-1", "start_pos": "198", "end_pos": "198", "site_lbl": "Ser198", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W4X7", "url": "https://www.uniprot.org/uniprotkb/Q9W4X7" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9W4X7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W4X7" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W542-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 986, "chemical_mass": 110427.0, "gene_names": "mip130;86E4.4;CG3480;Dmel\\CG3480;Dmel_CG3480;EG:86E4.4;Mip130/TWIT;Mip130/Twt;Mip130;TWIT;Twit;Twt;mip130;twit", "protein_name": "", "disease": [], "cellular_component": [ { "name": "DRM complex", "id": "GO:0070176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070176", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "Myb complex", "id": "GO:0031523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031523", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" }, { "name": "eggshell chorion gene amplification", "id": "GO:0007307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007307", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9W542", "url": "https://www.uniprot.org/uniprotkb/Q9W542" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W590-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 606, "chemical_mass": 70246.0, "gene_names": "Ns3;A60;BACN32G11.5;CG14788;Dmel\\CG14788;Dmel_CG14788;EG:BACN32G11.5;NS3;Ns3;dNS3;dmNuc3;l(1)2Ad;l(1)BA11;l(1)G0431;ns3", "protein_name": "Large subunit GTPase 1 homolog", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" }, { "name": "ribosomal subunit export from nucleus", "id": "GO:0000054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000054", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" }, { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" }, { "name": "regulation of insulin receptor signaling pathway", "id": "GO:0046626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046626", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W590-1", "start_pos": "368", "end_pos": "368", "site_lbl": "Thr368", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 368, "start_aa": "Thr", "end_pos": 368, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr368", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W590-1", "start_pos": "276", "end_pos": "276", "site_lbl": "Ser276", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W590", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W590" } ] } ] }, { "uniprot_canonical_ac": "Q9W590-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Ser279", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9W590", "url": "https://www.uniprot.org/uniprotkb/Q9W590" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9W590", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W590" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W5N0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W5N0", "url": "https://www.uniprot.org/uniprotkb/Q9W5N0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 266, "chemical_mass": 29640.0, "gene_names": "Coa7;CG13865;CG40301;COA7;Coa7;Dmel\\CG13865;Dmel_CG13865;FBgn0039965;dCOA7", "protein_name": "Cytochrome c oxidase assembly factor 7 homolog", "disease": [ { "disease_id": "DOID:0070465", "name": "autosomal recessive spinocerebellar ataxia with axonal neuropathy 3", "description": "An autosomal recessive cerebellar ataxia characterized by onset of slowly progressive axonal peripheral neuropathy in the first decade of life, evident in distal muscle weakness and atrophy and distal sensory impairment, followed by cerebellar ataxia and atrophy that has_material_basis_in homozygous or compound heterozygous mutation in the COA7 gene on chromosome 1p32.3.", "url": "https://disease-ontology.org/term/DOID:0070465", "evidence": [ { "id": "0070465", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070465" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q9W5N0", "url": "https://www.uniprot.org/uniprotkb/Q9W5N0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "Q9W5N0", "url": "https://www.uniprot.org/uniprotkb/Q9W5N0" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "Q9W5N0", "url": "https://www.uniprot.org/uniprotkb/Q9W5N0" } ], "pmid": "" }, { "name": "respiratory chain complex IV assembly", "id": "GO:0008535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008535", "evidence": [ { "database": "UniProtKB", "id": "Q9W5N0", "url": "https://www.uniprot.org/uniprotkb/Q9W5N0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9W5X9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W5X9", "url": "https://www.uniprot.org/uniprotkb/Q9W5X9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 287, "chemical_mass": 32383.0, "gene_names": "lky;CG17003;Dmel\\CG17003;lky", "protein_name": "Alpha-tubulin N-acetyltransferase 2", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9W5X9", "url": "https://www.uniprot.org/uniprotkb/Q9W5X9" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "Q9W5X9", "url": "https://www.uniprot.org/uniprotkb/Q9W5X9" } ], "pmid": "" }, { "name": "fusome", "id": "GO:0045169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045169", "evidence": [ { "database": "UniProtKB", "id": "Q9W5X9", "url": "https://www.uniprot.org/uniprotkb/Q9W5X9" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q9W5X9", "url": "https://www.uniprot.org/uniprotkb/Q9W5X9" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "Q9W5X9", "url": "https://www.uniprot.org/uniprotkb/Q9W5X9" } ], "pmid": "" }, { "name": "regulation of microtubule cytoskeleton organization", "id": "GO:0070507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070507", "evidence": [ { "database": "UniProtKB", "id": "Q9W5X9", "url": "https://www.uniprot.org/uniprotkb/Q9W5X9" } ], "pmid": "" } ], "molecular_function": [ { "name": "tubulin N-acetyltransferase activity", "id": "GO:0019799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019799", "evidence": [ { "database": "UniProtKB", "id": "Q9W5X9", "url": "https://www.uniprot.org/uniprotkb/Q9W5X9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9XTM1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 710, "chemical_mass": 82031.0, "gene_names": "Sec10;CG6159;Dmel\\CG6159;P71;Sec10p;Sec10;dSec10;dsec10;sec10", "protein_name": "Exocyst complex component 5", "disease": [ { "disease_id": "DOID:0070314", "name": "obstructive nephropathy", "description": "A kidney disease characterized by kidney damage and dysfunction resulting from urinary tract obstruction.", "url": "https://disease-ontology.org/term/DOID:0070314", "evidence": [ { "id": "0070314", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070314" } ], "weight": 0.0 }, { "disease_id": "DOID:0080332", "name": "bicuspid aortic valve disease", "description": "An aortic valve disease that is characterized by the presence of abnormal two-leaflet aortic valve in at least 2 first-degree relatives.", "url": "https://disease-ontology.org/term/DOID:0080332", "evidence": [ { "id": "0080332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080332" } ], "weight": 0.0 } ], "biological_process": [ { "name": "synaptic vesicle targeting", "id": "GO:0016080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016080", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "synaptic vesicle docking", "id": "GO:0016081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016081", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" } ], "molecular_function": [ { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" } ], "cellular_component": [ { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "Q9XTM1", "url": "https://www.uniprot.org/uniprotkb/Q9XTM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9XTN4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 704, "chemical_mass": 77514.0, "gene_names": "brk;BRK;Brk;CG9653;Dm brk;Dmel\\CG9653;Dmel_CG9653;brk;ssg-1", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" }, { "name": "cell competition in a multicellular organism", "id": "GO:0035212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035212", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" }, { "name": "wing disc morphogenesis", "id": "GO:0007472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007472", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" }, { "name": "posterior Malpighian tubule development", "id": "GO:0061328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061328", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "Q9XTN4", "url": "https://www.uniprot.org/uniprotkb/Q9XTN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9XTN4-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Thr130", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9XYZ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1140, "chemical_mass": 126045.0, "gene_names": "pic;0263/16;1258/16;1366/03;153636_at;263/16;CG7769;D-DDB1;DDB-1;DDB1;Dbd1;Ddb1;Dmel\\CG7769;PIC;d-ddb1;dDDB1;dDdb1;ddb1;l(3)87Dh;l(3)S136603;pic", "protein_name": "DNA damage-binding protein 1", "disease": [ { "disease_id": "DOID:0050427", "name": "xeroderma pigmentosum", "description": "A syndrome that is characterized by a deficiency in the ability to repair ultraviolet damage that has_material_basis_in autosomal recessive inheritance of DNA repair.", "url": "https://disease-ontology.org/term/DOID:0050427", "evidence": [ { "id": "0050427", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050427" } ], "weight": 0.0 }, { "disease_id": "DOID:2033", "name": "communication disorder", "description": "A specific developmental disorder that involves specific developmental disorders of speech and language.", "url": "https://disease-ontology.org/term/DOID:2033", "evidence": [ { "id": "2033", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2033" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "eggshell chorion gene amplification", "id": "GO:0007307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007307", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" }, { "name": "wing disc development", "id": "GO:0035220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035220", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ5", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9XZ08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 972, "chemical_mass": 111000.0, "gene_names": "botv;BcDNA:LD21192;Botv;CG15110;DEXT3;DEXTL3;DExt3;Dextl3;Dmel\\CG15110;EXTL3;Extl3;botv;dExt3", "protein_name": "Exostosin-3", "disease": [ { "disease_id": "DOID:206", "name": "hereditary multiple exostoses", "description": "An exostosis that has_material_basis_in a mutation on the genes EXT1, EXT2 and EXT3 which results in multiple bony spurs throughout a child's growth.", "url": "https://disease-ontology.org/term/DOID:206", "evidence": [ { "id": "206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:206" } ], "weight": 0.0 } ], "biological_process": [ { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" }, { "name": "glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0001888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001888", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9XZ08-1", "start_pos": "218", "end_pos": "218", "site_lbl": "Asn218", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 218, "start_aa": "Asn", "end_pos": 218, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn218", "evidence": [ { "id": "Q9XZ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ08-1", "start_pos": "606", "end_pos": "606", "site_lbl": "Asn606", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 606, "start_aa": "Asn", "end_pos": 606, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn606", "evidence": [ { "id": "Q9XZ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ08-1", "start_pos": "643", "end_pos": "643", "site_lbl": "Asn643", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 643, "start_aa": "Asn", "end_pos": 643, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn643", "evidence": [ { "id": "Q9XZ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ08-1", "start_pos": "843", "end_pos": "843", "site_lbl": "Asn843", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 843, "start_aa": "Asn", "end_pos": 843, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn843", "evidence": [ { "id": "Q9XZ08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ08-1", "start_pos": "669", "end_pos": "669", "site_lbl": "Pro669", "weight": 0.0, "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "In botv510; induces defects in wing patterning due to impaired movement of morphogens.", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" }, { "database": "PubMed", "id": "14645127", "url": "https://glygen.org/publication/PubMed/14645127" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ08-1", "start_pos": "707", "end_pos": "707", "site_lbl": "Gly707", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In botv8; induces defects in wing patterning due to impaired movement of morphogens.", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" }, { "database": "PubMed", "id": "14998928", "url": "https://glygen.org/publication/PubMed/14998928" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ08-1", "start_pos": "821", "end_pos": "821", "site_lbl": "Gly821", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "D", "comment": "In botv514; induces defects in wing patterning due to impaired movement of morphogens.", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ08", "url": "https://www.uniprot.org/uniprotkb/Q9XZ08" }, { "database": "PubMed", "id": "14645127", "url": "https://glygen.org/publication/PubMed/14645127" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9XZ14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9XZ14", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 879, "chemical_mass": 100068.0, "gene_names": "goe;BcDNA:LD21405;CG9634;Dmel\\CG9634;Dmel_CG9634;Nepl2;goe", "protein_name": "Protein gone early", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ14", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ14", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ14", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14" } ], "pmid": "" }, { "name": "negative regulation of stem cell differentiation", "id": "GO:2000737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000737", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ14", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9XZ14-1", "start_pos": "180", "end_pos": "180", "site_lbl": "Asn180", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 180, "start_aa": "Asn", "end_pos": 180, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn180", "evidence": [ { "id": "Q9XZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ14-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Asn539", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 539, "start_aa": "Asn", "end_pos": 539, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn539", "evidence": [ { "id": "Q9XZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ14-1", "start_pos": "701", "end_pos": "701", "site_lbl": "Asn701", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 701, "start_aa": "Asn", "end_pos": 701, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn701", "evidence": [ { "id": "Q9XZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q9XZ14-1", "start_pos": "853", "end_pos": "853", "site_lbl": "Asn853", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 853, "start_aa": "Asn", "end_pos": 853, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn853", "evidence": [ { "id": "Q9XZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ14#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9XZT6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 250, "chemical_mass": 29088.0, "gene_names": "dnk;CG5452;DM-dNK;DNK;Dm-dNK;DmdNK;Dmel\\CG5452;dNK;dnk", "protein_name": "Deoxynucleoside kinase", "disease": [ { "disease_id": "DOID:0080120", "name": "mitochondrial DNA depletion syndrome 2", "description": "A mitochondrial DNA depletion syndrome that is characterized by childhood onset of muscle weakness associated with depletion of mtDNA in skeletal muscle, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the mitochondrial thymidine kinase gene on chromosome 16q21.", "url": "https://disease-ontology.org/term/DOID:0080120", "evidence": [ { "id": "0080120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080120" } ], "weight": 0.0 }, { "disease_id": "DOID:0111523", "name": "autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 3", "description": "A chronic progressive external ophthalmoplegia that has_material_basis_in homozygous or compound heterozygous mutation in TK2 on chromosome 16q21.", "url": "https://disease-ontology.org/term/DOID:0111523", "evidence": [ { "id": "0111523", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111523" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA biosynthetic process", "id": "GO:0071897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071897", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "nucleoside phosphate biosynthetic process", "id": "GO:1901293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901293", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "nucleoside salvage", "id": "GO:0043174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043174", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" } ], "molecular_function": [ { "name": "deoxyguanosine kinase activity", "id": "GO:0004138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004138", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "uridine kinase activity", "id": "GO:0004849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004849", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "deoxycytidine kinase activity", "id": "GO:0004137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004137", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "thymidine kinase activity", "id": "GO:0004797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004797", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "deoxynucleoside kinase activity", "id": "GO:0019136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019136", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "deoxyadenosine kinase activity", "id": "GO:0004136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004136", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "cytidine kinase activity", "id": "GO:0043771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043771", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9XZT6-1", "start_pos": "236", "end_pos": "236", "site_lbl": "Ser236", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9XZT6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9XZT6" } ] } ] }, { "uniprot_canonical_ac": "Q9XZT6-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Ser241", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" }, { "database": "PubMed", "id": "17372656", "url": "https://glygen.org/publication/PubMed/17372656" }, { "database": "iPTMnet", "id": "Q9XZT6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9XZT6" } ] } ] }, { "uniprot_canonical_ac": "Q9XZT6-1", "start_pos": "243", "end_pos": "243", "site_lbl": "Ser243", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "iPTMnet", "id": "Q9XZT6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9XZT6" } ] } ] }, { "uniprot_canonical_ac": "Q9XZT6-1", "start_pos": "45", "end_pos": "45", "site_lbl": "Asn45", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "D", "comment": "Reduces enzyme activity towards dA, dG, dT and dC about 5-fold.", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" }, { "database": "PubMed", "id": "16008571", "url": "https://glygen.org/publication/PubMed/16008571" } ] } ] }, { "uniprot_canonical_ac": "Q9XZT6-1", "start_pos": "64", "end_pos": "64", "site_lbl": "Asn64", "weight": 0.0, "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "D", "comment": "Reduces enzyme activity towards dT and dC about 500-fold. Reduces enzyme activity towards dG about 3900-fold. Reduces enzyme activity towards dA about 900-fold.", "evidence": [ { "database": "UniProtKB", "id": "Q9XZT6", "url": "https://www.uniprot.org/uniprotkb/Q9XZT6" }, { "database": "PubMed", "id": "16008571", "url": "https://glygen.org/publication/PubMed/16008571" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9Y0A7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 198, "chemical_mass": 22569.0, "gene_names": "amos;Amos;CG10393;Dmel\\CG10393;Roi;Tft;amos;asolo;bHLHa10;rolo", "protein_name": "Basic helix-loop-helix transcription factor amos", "disease": [ { "disease_id": "DOID:0060282", "name": "persistent hyperplastic primary vitreous", "description": "A developmental vitreous disease that is characterized by leukocoria, strabismus and vision loss, caused by failure of primary vitreous and hyaloid vasculature to regress during embryological development.", "url": "https://disease-ontology.org/term/DOID:0060282", "evidence": [ { "id": "0060282", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060282" } ], "weight": 0.0 }, { "disease_id": "DOID:0070612", "name": "autosomal dominant nonsyndromic deafness 89", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the ATOH1 gene on chromosome 4q22.", "url": "https://disease-ontology.org/term/DOID:0070612", "evidence": [ { "id": "0070612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070612" } ], "weight": 0.0 } ], "biological_process": [ { "name": "sensory organ boundary specification", "id": "GO:0008052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008052", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "neuron fate commitment", "id": "GO:0048663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048663", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "axon development", "id": "GO:0061564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061564", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "sensory organ precursor cell fate determination", "id": "GO:0016360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016360", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0A7", "url": "https://www.uniprot.org/uniprotkb/Q9Y0A7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9Y117-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 667, "chemical_mass": 76807.0, "gene_names": "Pgant3;BcDNA:GH09147;CG4445;Dmel\\CG4445;Pgant3;anon-WO0118547.119;pgant3;ppGalNAcT3", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 3", "disease": [], "biological_process": [ { "name": "regulation of cell adhesion mediated by integrin", "id": "GO:0033628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033628", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" }, { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" }, { "name": "protein O-linked glycosylation via N-acetyl-galactosamine", "id": "GO:0016266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016266", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" }, { "name": "cell-substrate adhesion", "id": "GO:0031589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031589", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" }, { "name": "extracellular matrix constituent secretion", "id": "GO:0070278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070278", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" }, { "name": "polypeptide N-acetylgalactosaminyltransferase activity", "id": "GO:0004653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004653", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9Y117-1", "start_pos": "129", "end_pos": "129", "site_lbl": "Asn129", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 129, "start_aa": "Asn", "end_pos": 129, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn129", "evidence": [ { "id": "Q9Y117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y117#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9Y117-1", "start_pos": "279", "end_pos": "279", "site_lbl": "Asn279", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 279, "start_aa": "Asn", "end_pos": 279, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn279", "evidence": [ { "id": "Q9Y117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y117#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9Y117-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Asn313", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 313, "start_aa": "Asn", "end_pos": 313, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn313", "evidence": [ { "id": "Q9Y117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y117#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9Y117-1", "start_pos": "433", "end_pos": "433", "site_lbl": "Asn433", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 433, "start_aa": "Asn", "end_pos": 433, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn433", "evidence": [ { "id": "Q9Y117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y117#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9Y117-1", "start_pos": "590", "end_pos": "590", "site_lbl": "Asn590", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 590, "start_aa": "Asn", "end_pos": 590, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn590", "evidence": [ { "id": "Q9Y117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y117#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9Y117-1", "start_pos": "75", "end_pos": "75", "site_lbl": "Asn75", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 75, "start_aa": "Asn", "end_pos": 75, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn75", "evidence": [ { "id": "Q9Y117", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y117#ptm_processing" } ] } ] }, { "uniprot_canonical_ac": "Q9Y117-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Arg130", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "C", "comment": "Does not affect subcellular location. Loss of catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y117", "url": "https://www.uniprot.org/uniprotkb/Q9Y117" }, { "database": "PubMed", "id": "20371600", "url": "https://glygen.org/publication/PubMed/20371600" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9Y118-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 431, "chemical_mass": 47046.0, "gene_names": "PolD3;BG:DS07295.3;BcDNA:GH08865;CG3975;DNApolD3;Dmel\\CG3975;Pol32;PolD3;pol32;rd", "protein_name": "DNA polymerase delta subunit 3", "disease": [], "molecular_function": [ { "name": "DNA polymerase processivity factor activity", "id": "GO:0030337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030337", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" } ], "cellular_component": [ { "name": "delta DNA polymerase complex", "id": "GO:0043625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043625", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "zeta DNA polymerase complex", "id": "GO:0016035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016035", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "protein-containing complex localization", "id": "GO:0031503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031503", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "double-strand break repair via break-induced replication", "id": "GO:0000727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000727", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "error-prone translesion synthesis", "id": "GO:0042276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042276", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "mitotic DNA replication", "id": "GO:1902969", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902969", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" }, { "name": "DNA synthesis involved in double-strand break repair via homologous recombination", "id": "GO:0043150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043150", "evidence": [ { "database": "UniProtKB", "id": "Q9Y118", "url": "https://www.uniprot.org/uniprotkb/Q9Y118" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "Q9Y140-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9Y140", "url": "https://www.uniprot.org/uniprotkb/Q9Y140" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 326, "chemical_mass": 35744.0, "gene_names": "BcDNA:GH06026;CG7601;DHRS7B;Dmel\\CG7601", "protein_name": "Dehydrogenase/reductase SDR family protein 7-like", "disease": [], "cellular_component": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "Q9Y140", "url": "https://www.uniprot.org/uniprotkb/Q9Y140" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9Y140", "url": "https://www.uniprot.org/uniprotkb/Q9Y140" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q9Y140", "url": "https://www.uniprot.org/uniprotkb/Q9Y140" } ], "pmid": "" } ], "molecular_function": [ { "name": "acylglycerone-phosphate reductase (NADP+) activity", "id": "GO:0000140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000140", "evidence": [ { "database": "UniProtKB", "id": "Q9Y140", "url": "https://www.uniprot.org/uniprotkb/Q9Y140" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A023GRW3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A023GRW3", "url": "https://www.uniprot.org/uniprotkb/A0A023GRW3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 949, "chemical_mass": 107664.0, "gene_names": "Dmel\\CG4896;CG4896;Dmel\\CG4896;Dmel_CG4896;cg4896", "protein_name": "RNA-binding protein 5-A", "disease": [ { "disease_id": "DOID:0111780", "name": "TARP syndrome", "description": "A syndrome characterized by talipes equinovarus, atrial septal defect, Robin sequence (micrognathia, cleft palate, and glossoptosis), and persistent left superior vena cava typically resulting in late prenatal or early postnatal mortality that has_material_basis_in hemizygous mutation in the RBM10 gene on chromosome Xp11.3.", "url": "https://disease-ontology.org/term/DOID:0111780", "evidence": [ { "id": "0111780", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111780" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A023GRW3", "url": "https://www.uniprot.org/uniprotkb/A0A023GRW3" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A023GRW3", "url": "https://www.uniprot.org/uniprotkb/A0A023GRW3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A023GRW3", "url": "https://www.uniprot.org/uniprotkb/A0A023GRW3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A023GRW3", "url": "https://www.uniprot.org/uniprotkb/A0A023GRW3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A023GRW3", "url": "https://www.uniprot.org/uniprotkb/A0A023GRW3" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A023GRW3", "url": "https://www.uniprot.org/uniprotkb/A0A023GRW3" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A023GRW3", "url": "https://www.uniprot.org/uniprotkb/A0A023GRW3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4JCS8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCS8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JCS8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 10639.0, "gene_names": "CG12901;CG12901;CG42733;Dmel\\CG42733;Dmel_CG42733;Tes85-2", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4JCV0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCV0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JCV0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 84, "chemical_mass": 9282.0, "gene_names": "Dmel\\CG42753;CG42753;Dmel\\CG42753;Dmel_CG42753", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4JCV9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCV9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JCV9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 64, "chemical_mass": 7489.0, "gene_names": "Dmel\\CG42851;CG42851;Dmel\\CG42851;Dmel_CG42851;chr2R_20696695_20697629.0", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4JCX8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCX8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JCX8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 146, "chemical_mass": 17144.0, "gene_names": "HDC14119;CG34053;CG42824;Dmel\\CG42824;Dmel_CG42824;FBgn0262006;HDC14119", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4JD85-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JD85", "url": "https://www.uniprot.org/uniprotkb/A0A0B4JD85" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 140, "chemical_mass": 15710.0, "gene_names": "Dmel\\CG42691;CG42691;Dmel\\CG42691;Dmel_CG42691", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K650-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K650", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K650" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 152, "chemical_mass": 17854.0, "gene_names": "chr3R_10081851_10082659.0;CG43179;Dmel\\CG43179;Dmel_CG43179;chr3R_10081851_10082659.0", "protein_name": "Serine protease gd N-terminal domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K6E5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6E5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6E5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 114, "chemical_mass": 13229.0, "gene_names": "Dmel\\CG34289;CG34289;Dmel\\CG34289;Dmel_CG34289", "protein_name": "RING-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6E5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6E5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K6I6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6I6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6I6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 508, "chemical_mass": 55454.0, "gene_names": "CT19744;Dmel\\CG31075;150697_at;CG31075;CG6309;CT19744;Dmel\\CG31075;Dmel_CG31075;GH20910p", "protein_name": "Aldehyde dehydrogenase domain-containing protein", "disease": [ { "disease_id": "DOID:3827", "name": "congenital diaphragmatic hernia", "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs.", "url": "https://disease-ontology.org/term/DOID:3827", "evidence": [ { "id": "3827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3827" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6I6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6I6" } ], "pmid": "" } ], "biological_process": [ { "name": "aldehyde metabolic process", "id": "GO:0006081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006081", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6I6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6I6" } ], "pmid": "" } ], "molecular_function": [ { "name": "retinal dehydrogenase (NAD+) activity", "id": "GO:0001758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001758", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6I6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6I6" } ], "pmid": "" }, { "name": "aldehyde dehydrogenase (NAD+) activity", "id": "GO:0004029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004029", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6I6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6I6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4K6I6-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K7S6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1965, "chemical_mass": 218731.0, "gene_names": "mld;CG13620;CG31312;CG33343;CG34100;CG9469;DTS-3;Dmel\\CG34100;Dmel_CG34100;L(3)3[DTS];Mld;l(3)3[DTS];l(3)DTS3;mld", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of circadian sleep/wake cycle, sleep", "id": "GO:0045938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045938", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" }, { "name": "ecdysone biosynthetic process", "id": "GO:0006697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006697", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7S6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4K7S6-1", "start_pos": "1698", "end_pos": "1698", "site_lbl": "Thr1698", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1698, "start_aa": "Thr", "end_pos": 1698, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1698", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7S6-1", "start_pos": "794", "end_pos": "794", "site_lbl": "Thr794", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 794, "start_aa": "Thr", "end_pos": 794, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr794", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7S6-1", "start_pos": "823", "end_pos": "823", "site_lbl": "Thr823", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 823, "start_aa": "Thr", "end_pos": 823, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr823", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K6Q5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6Q5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 365, "chemical_mass": 41219.0, "gene_names": "PIG-L;CG4433;Dmel\\CG4433;Dmel_CG4433;PIG-L;PIGL", "protein_name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "disease": [ { "disease_id": "DOID:0112152", "name": "CHIME syndrome", "description": "A syndrome characterized by colobomas, congenital heart defects, migratory ichthyosiform dermatosis, intellectual disability, and ear anomalies that has_material_basis_in homozygous or compound heterozygous mutation in the PIGL gene on chromosome 17p11.2.", "url": "https://disease-ontology.org/term/DOID:0112152", "evidence": [ { "id": "0112152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112152" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6Q5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6Q5" } ], "pmid": "" } ], "molecular_function": [ { "name": "N-acetylglucosaminylphosphatidylinositol deacetylase activity", "id": "GO:0000225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000225", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6Q5" } ], "pmid": "" } ], "biological_process": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6Q5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K6S7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6S7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6S7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 103, "chemical_mass": 12175.0, "gene_names": "CG30492;CG30492;CG43341;Dmel\\CG43341;Dmel_CG43341", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K701-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K701", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K701" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 234, "chemical_mass": 26689.0, "gene_names": "Pex11c;BcDNA:RE30473;CG13827;Dmel\\CG13827;Dmel_CG13827;PEX11C;Pex11c;Pex11", "protein_name": "", "disease": [], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K701", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K701" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K701", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K701" } ], "pmid": "" } ], "biological_process": [ { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K701", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K701" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K759-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K759", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K759" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 74, "chemical_mass": 5940.0, "gene_names": "Dmel\\CG14742;CG14742;DMG8-chr3R.14.009;Dmel\\CG14742;Dmel_CG14742", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K764-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K764", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K764" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 48, "chemical_mass": 5310.0, "gene_names": "Dmel\\CG43630;CG43630;Dmel\\CG43630;Dmel_CG43630", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K7B4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7B4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7B4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 172, "chemical_mass": 19648.0, "gene_names": "Dmel\\CG43318;CG14876;CG43318;Dmel\\CG43318;Dmel_CG43318", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K7C5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 220, "chemical_mass": 24435.0, "gene_names": "Fkbp14;BcDNA.GM07659;BcDNA:GH08925;BcDNA:GM07659;CG9847;Dmel\\CG9847;Dmel_CG9847;FKB13;FKBP13;FKBP14;Fkbp13;Fkbp14;GM07659;fkbp13;l(2)00734", "protein_name": "peptidylprolyl isomerase", "disease": [ { "disease_id": "DOID:0080735", "name": "Ehlers-Danlos syndrome kyphoscoliotic type 2", "description": "An Ehlers-Danlos syndrome that is characterized by severe muscle hypotonia at birth, progressive scoliosis, joint hypermobility, hyperelastic skin, myopathy, sensorineural hearing impairment, and normal pyridinoline excretion in urine and that has_material_basis_in homozygous or compound heterozygous mutation in the FKBP14 gene on chromosome 7p15.", "url": "https://disease-ontology.org/term/DOID:0080735", "evidence": [ { "id": "0080735", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080735" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" } ], "biological_process": [ { "name": "muscle cell cellular homeostasis", "id": "GO:0046716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046716", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" }, { "name": "imaginal disc development", "id": "GO:0007444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007444", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" }, { "name": "imaginal disc-derived wing margin morphogenesis", "id": "GO:0008587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008587", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K7C7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7C7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 90, "chemical_mass": 10318.0, "gene_names": "Dmel\\CG43094;CG43094;Dmel\\CG43094;Dmel_CG43094", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K7E8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7E8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7E8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 73, "chemical_mass": 8245.0, "gene_names": "Dmel\\CG43207;CG43207;DMG8-chr2R.33.031;Dmel\\CG43207;Dmel_CG43207;lincRNA.382", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K7I9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7I9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7I9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 82, "chemical_mass": 9086.0, "gene_names": "Dmel\\CG43267;CG43267;Dmel\\CG43267;Dmel_CG43267", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K7X0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7X0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7X0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 141, "chemical_mass": 16183.0, "gene_names": "Dmel\\CG43111;CG43111;Dmel\\CG43111;Dmel_CG43111", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K838-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K838", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K838" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 66, "chemical_mass": 7709.0, "gene_names": "Dmel\\CG43324;CG15844;CG43324;Dmel\\CG43324;Dmel_CG43324", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "disease": [], "molecular_function": [ { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K838", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K838" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K838", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K838" } ], "pmid": "" } ], "cellular_component": [ { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K838", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K838" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4K8B1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K8B1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K8B1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 342, "chemical_mass": 38190.0, "gene_names": "Dmel\\CG13562;CG13562;Dmel\\CG13562;Dmel_CG13562", "protein_name": "Lipase domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K8B1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K8B1" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K8B1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K8B1" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K8B1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K8B1" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K8B1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K8B1" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K8B1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K8B1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KED2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KED2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KED2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 293, "chemical_mass": 33068.0, "gene_names": "Dmel\\CG44102;CG44102;Dmel\\CG44102;Dmel_CG44102", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KEH1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEH1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEH1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 710, "chemical_mass": 79999.0, "gene_names": "FBXL9;CG8272;CT8327;Dmel\\CG8272;Dmel_CG8272;FBXL9", "protein_name": "F-box domain-containing protein", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEH1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEH1" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEH1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEH1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KEN4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 608, "chemical_mass": 68932.0, "gene_names": "Vang;CG8075;Dmel\\CG8075;Dmel_CG8075;Stbm;Stb;Strabismus;VANG;Van Gogh;Vang/Stbm;Vangl;Vang;stbm/vang;stbm;stb;strabismus/Van Gogh;strabismus;vang/stbm;vangogh/strabismus;vang", "protein_name": "Vang-like protein", "disease": [ { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 }, { "disease_id": "DOID:0080074", "name": "neural tube defect", "description": "A physical disorder characterized by incomplete closure of the neural tube.", "url": "https://disease-ontology.org/term/DOID:0080074", "evidence": [ { "id": "0080074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080074" } ], "weight": 0.0 }, { "disease_id": "DOID:0080700", "name": "caudal regression syndrome", "description": "A physical disorder that is characterized by impairment of the development of the lower half of the body.", "url": "https://disease-ontology.org/term/DOID:0080700", "evidence": [ { "id": "0080700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080700" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of axon extension", "id": "GO:0045773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045773", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "Wnt signaling pathway, planar cell polarity pathway", "id": "GO:0060071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060071", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "morphogenesis of a polarized epithelium", "id": "GO:0001738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001738", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "establishment of planar polarity", "id": "GO:0001736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001736", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "positive regulation of axon guidance", "id": "GO:1902669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902669", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "establishment of imaginal disc-derived wing hair orientation", "id": "GO:0001737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "ommatidial rotation", "id": "GO:0016318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016318", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" }, { "name": "establishment of ommatidial planar polarity", "id": "GO:0042067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042067", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEN4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEN4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KEY2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEY2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KEY2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 86, "chemical_mass": 9534.0, "gene_names": "Dmel\\CG43659;CG43659;Dm_2R:85606;Dmel\\CG43659;Dmel_CG43659", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KF86-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 852, "chemical_mass": 96352.0, "gene_names": "Atg9;ATG9;Atg9a;Atg9;CG3615;Dmel\\CG3615;Dmel_CG3615;atg9;dAtg9", "protein_name": "Autophagy-related protein 9", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "intestinal epithelial structure maintenance", "id": "GO:0060729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060729", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "larval midgut histolysis", "id": "GO:0035069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035069", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "larval midgut cell programmed cell death", "id": "GO:0035096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035096", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" } ], "molecular_function": [ { "name": "phospholipid scramblase activity", "id": "GO:0017128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017128", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF86", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF86" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KF86-1", "start_pos": "747", "end_pos": "747", "site_lbl": "Thr747", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 747, "start_aa": "Thr", "end_pos": 747, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr747", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KFC9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 881, "chemical_mass": 98662.0, "gene_names": "Dmel\\CG10073;CG10073;Dmel\\CG10073;Dmel_CG10073;FBgn0034440", "protein_name": "FXNA-like protease", "disease": [ { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC9" } ], "pmid": "" }, { "name": "metalloexopeptidase activity", "id": "GO:0008235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008235", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC9" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFC9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFC9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KFF2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFF2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFF2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 474, "chemical_mass": 53497.0, "gene_names": "Dmel\\CG43742;CG43742;Dmel\\CG43742;Dmel_CG43742;SP251", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFF2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFF2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFF2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFF2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFF2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFF2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFF2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFF2" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFF2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFF2" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFF2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFF2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KFL3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 605, "chemical_mass": 66877.0, "gene_names": "Kat60;CG10229;Dm-Kat60;DmCG10229;Dmel\\CG10229;Dmel_CG10229;KATNA1;Kat-60;Kat60;Katanin-60;kat-60;kat60;katanin-60;katanin60-dm", "protein_name": "Katanin p60 ATPase-containing subunit A1", "disease": [], "molecular_function": [ { "name": "microtubule severing ATPase activity", "id": "GO:0008568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008568", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "myosin binding", "id": "GO:0017022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule severing", "id": "GO:0051013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051013", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "microtubule depolymerization", "id": "GO:0007019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007019", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFL3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KFQ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 316, "chemical_mass": 36255.0, "gene_names": "Tsp86D;CG4591;Dm.Tsp86D;Dmel\\CG4591;Dmel_CG4591;Tsp86D;tsp86D", "protein_name": "Tetraspanin-33", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" }, { "name": "pore complex", "id": "GO:0046930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046930", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFQ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KFY0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 696, "chemical_mass": 75598.0, "gene_names": "dnr1;CG12489;DNR1;Dmel\\CG12489;Dmel_CG12489;Dnr-1;Dnr1;Mylip;dNR1;dnr1", "protein_name": "RING-type E3 ubiquitin transferase", "disease": [ { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "sleep", "id": "GO:0030431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030431", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria", "id": "GO:0002814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002814", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "negative regulation of peptidoglycan recognition protein signaling pathway", "id": "GO:0061060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061060", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" }, { "name": "negative regulation of antibacterial peptide biosynthetic process", "id": "GO:0002809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002809", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KFZ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 297, "chemical_mass": 32447.0, "gene_names": "Eglp4;Aqp4019;CG4019;Dmel\\CG4019;Dmel_CG4019;Eglp 4;Eglp4", "protein_name": "", "disease": [ { "disease_id": "DOID:0080122", "name": "Alpers-Huttenlocher syndrome", "description": "A mitochondrial DNA depletion syndrome that is characterized by a clinical triad of psychomotor retardation, intractable epilepsy, and liver failure in infants and young children, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the nuclear gene encoding mitochondrial DNA polymerase gamma (POLG) on chromosome 15q26.", "url": "https://disease-ontology.org/term/DOID:0080122", "evidence": [ { "id": "0080122", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080122" } ], "weight": 0.0 }, { "disease_id": "DOID:0080315", "name": "megalencephalic leukoencephalopathy with subcortical cysts", "description": "A leukodystorphy characterized by infantile-onset macrocephaly, often with mild neurologic signs at presentation (such as mild motor delay), which worse with time, leading to poor ambulation, falls, ataxia, spasticity, increasing seizures and cognitive decline.", "url": "https://disease-ontology.org/term/DOID:0080315", "evidence": [ { "id": "0080315", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080315" } ], "weight": 0.0 }, { "disease_id": "DOID:0080743", "name": "transverse myelitis", "description": "A myelitis that is characterized by a band-like sensation across the trunk of the body, with sensory changes below.", "url": "https://disease-ontology.org/term/DOID:0080743", "evidence": [ { "id": "0080743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080743" } ], "weight": 0.0 }, { "disease_id": "DOID:0081061", "name": "nephrogenic diabetes insipidus type 2", "description": "A nephrogenic diabetes insipidus that is characterized by the inability of the renal collecting ducts to absorb water in response to antidiuretic hormone and that has_material_basis_in heterozygous, homozygous, or compound heterozygous mutation in the gene encoding the aquaporin-2 water channel (AQP2), which maps to chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0081061", "evidence": [ { "id": "0081061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081061" } ], "weight": 0.0 }, { "disease_id": "DOID:0110251", "name": "cataract 15 multiple types", "description": "A cataract that has_material_basis_in heterozygous mutation in the MIP gene on chromosome 12q13.", "url": "https://disease-ontology.org/term/DOID:0110251", "evidence": [ { "id": "0110251", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110251" } ], "weight": 0.0 }, { "disease_id": "DOID:0110861", "name": "autosomal recessive polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion.", "url": "https://disease-ontology.org/term/DOID:0110861", "evidence": [ { "id": "0110861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110861" } ], "weight": 0.0 }, { "disease_id": "DOID:0111707", "name": "Bothnian type palmoplantar keratoderma", "description": "A nonepidermolytic palmoplantar keratoderma characterized by a diffuse nonepidermolytic form of palmoplantar keratoderma where the affected areas take on a white, spongy appearance upon exposure to water that has_material_basis_in heterozygous mutation in the AQP5 gene on chromosome 12q13.12.", "url": "https://disease-ontology.org/term/DOID:0111707", "evidence": [ { "id": "0111707", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111707" } ], "weight": 0.0 }, { "disease_id": "DOID:10140", "name": "dry eye syndrome", "description": "A lacrimal apparatus disease that is characterized by persistent irritation or burning of the coreneal surface.", "url": "https://disease-ontology.org/term/DOID:10140", "evidence": [ { "id": "10140", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10140" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 }, { "disease_id": "DOID:1210", "name": "optic neuritis", "description": "An optic nerve disease that results_in inflammation located_in optic nerve which may cause a complete or partial loss of vision.", "url": "https://disease-ontology.org/term/DOID:1210", "evidence": [ { "id": "1210", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1210" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:12387", "name": "nephrogenic diabetes insipidus", "description": "A diabetes insipidus that is characterized by a complete or partial resistance of the kidneys to vasopressin (ADH).", "url": "https://disease-ontology.org/term/DOID:12387", "evidence": [ { "id": "12387", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12387" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:1432", "name": "blindness", "description": "An eye disease characterized by a lack or loss of vision.", "url": "https://disease-ontology.org/term/DOID:1432", "evidence": [ { "id": "1432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1432" } ], "weight": 0.0 }, { "disease_id": "DOID:1727", "name": "retinal vein occlusion", "description": "", "url": "https://disease-ontology.org/term/DOID:1727", "evidence": [ { "id": "1727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1727" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1837", "name": "diabetic ketoacidosis", "description": "A metabolic acidosis that is characterized by the shift of acid-base status of the body toward the acid side accompanied by the accumulation of ketone bodies in body tissues and fluids, resulting from uncontrolled diabetes mellitus.", "url": "https://disease-ontology.org/term/DOID:1837", "evidence": [ { "id": "1837", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1837" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:3275", "name": "thymoma", "description": "A thymus cancer that derives_from epithelial cells located_in the thymus. The tumor cells in a thymoma look similar to the normal cells of the thymus, grow slowly, and rarely spread beyond the thymus.", "url": "https://disease-ontology.org/term/DOID:3275", "evidence": [ { "id": "3275", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3275" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:4724", "name": "brain edema", "description": "A brain disease that is characterized by excess accumulation of fluid in the intracellular and/or extracellular spaces of the brain, has_symptom nausea, has_symptom vomiting, has_symptom blurred vision, has_symptom seizure, has_symptom coma.", "url": "https://disease-ontology.org/term/DOID:4724", "evidence": [ { "id": "4724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4724" } ], "weight": 0.0 }, { "disease_id": "DOID:5679", "name": "retinal disease", "description": "An eye disease that is located_in the retina.", "url": "https://disease-ontology.org/term/DOID:5679", "evidence": [ { "id": "5679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5679" } ], "weight": 0.0 }, { "disease_id": "DOID:636", "name": "central pontine myelinolysis", "description": "A demyelination disease that is characterized by severe damage to the myelin sheath of the pons' nerve cells and has_symptom acute paralysis, has_symptom dysphagia, and has_symptom dysarthria.", "url": "https://disease-ontology.org/term/DOID:636", "evidence": [ { "id": "636", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:636" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:8869", "name": "neuromyelitis optica", "description": "A central nervous system disease characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis).", "url": "https://disease-ontology.org/term/DOID:8869", "evidence": [ { "id": "8869", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8869" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9246", "name": "cerebral amyloid angiopathy", "description": "An amyloidosis where amyloid protein progressively deposits in cerebral blood vessel walls with subsequent degenerative vascular changes that usually result in spontaneous cerebral hemorrhage, ischemic lesions and progressive dementia.", "url": "https://disease-ontology.org/term/DOID:9246", "evidence": [ { "id": "9246", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9246" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9409", "name": "diabetes insipidus", "description": "A kidney disease that is characterized by polydipsia and polyuria with a dilute urine having a specific gravity less than 1.010, hypernatremia, and dehydration.", "url": "https://disease-ontology.org/term/DOID:9409", "evidence": [ { "id": "9409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9409" } ], "weight": 0.0 }, { "disease_id": "DOID:9428", "name": "intracranial hypertension", "description": "A brain disease that is characterized by high pressure inside the skull, the brain tissue and cerebrospinal fluid, has_symptom headache, has_symptom vomiting, has_symptom altered mental status, has_symptom papilledema.", "url": "https://disease-ontology.org/term/DOID:9428", "evidence": [ { "id": "9428", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9428" } ], "weight": 0.0 }, { "disease_id": "DOID:9849", "name": "Meniere's disease", "description": "A vestibular disease characterized by vertigo, low-pitched tinnitus and hearing loss.", "url": "https://disease-ontology.org/term/DOID:9849", "evidence": [ { "id": "9849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9849" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" }, { "name": "water transport", "id": "GO:0006833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006833", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" }, { "name": "renal system process", "id": "GO:0003014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003014", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" } ], "molecular_function": [ { "name": "channel activity", "id": "GO:0015267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015267", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" }, { "name": "water channel activity", "id": "GO:0015250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015250", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFZ1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KFZ1-1", "start_pos": "119", "end_pos": "119", "site_lbl": "Thr119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 119, "start_aa": "Thr", "end_pos": 119, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr119", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KGB6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGB6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGB6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 43, "chemical_mass": 4865.0, "gene_names": "Dmel\\CG44174;CG44174;Dmel\\CG44174;Dmel_CG44174;lincRNA.811", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KGD2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGD2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGD2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 50, "chemical_mass": 5702.0, "gene_names": "Dmel\\CG44038;CG44038;Dmel\\CG44038;Dmel_CG44038;FBgn0264830", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KGE5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1207, "chemical_mass": 130151.0, "gene_names": "bon;0241/08;0249/12;0434/20;0487/06;06;08;12;150268_at;150269_at;20;Bonus;Bon;CG15687;CG5206;Dmel\\CG5206;Dmel_CG5206;anon-WO0118547.418;bon;l(3)S043420", "protein_name": "", "disease": [], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" }, { "name": "epidermal cell fate specification", "id": "GO:0009957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009957", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGE5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KGE5-1", "start_pos": "452", "end_pos": "452", "site_lbl": "Thr452", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 452, "start_aa": "Thr", "end_pos": 452, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr452", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KGH8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGH8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 202, "chemical_mass": 21344.0, "gene_names": "Dmel\\CG34135;CG34135;Dmel\\CG34135;Dmel_CG34135", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KGI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1408, "chemical_mass": 157866.0, "gene_names": "Mrp5;CG4562;CT14766;DmCG4562;Dme_CG4562;Dmel\\CG4562;Dmel_CG4562;Mrp5;dMRP5", "protein_name": "", "disease": [ { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "pmid": "" }, { "name": "ABC-type heme transporter activity", "id": "GO:0015439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015439", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "pmid": "" }, { "name": "heme export", "id": "GO:0097037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097037", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KGI4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGI4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGI4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 198, "chemical_mass": 22126.0, "gene_names": "Dmel\\CG31206;CG31206;Dmel\\CG31206;Dmel_CG31206;NEST:bs16c12", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KGW6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 509, "chemical_mass": 51274.0, "gene_names": "Ssdp;CG7187;Dmel\\CG7187;Dmel_CG7187;Ssdp;l(3)neo48;ssdp", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" } ], "molecular_function": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" }, { "name": "sequence-specific single stranded DNA binding", "id": "GO:0098847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098847", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGW6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KGW6-1", "start_pos": "65", "end_pos": "65", "site_lbl": "Val65", "weight": 0.0, "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "K", "comment": "Impairs interaction with Chi.", "evidence": [ { "database": "UniProtKB", "id": "Q9VEB9", "url": "https://www.uniprot.org/uniprotkb/Q9VEB9" }, { "database": "PubMed", "id": "31570581", "url": "https://glygen.org/publication/PubMed/31570581" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KGW6-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Phe66", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "E", "comment": "Impairs interaction with Chi; when associated with A-69 and A-70.", "evidence": [ { "database": "UniProtKB", "id": "Q9VEB9", "url": "https://www.uniprot.org/uniprotkb/Q9VEB9" }, { "database": "PubMed", "id": "31570581", "url": "https://glygen.org/publication/PubMed/31570581" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KGW6-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Asp68", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "R", "comment": "Impairs interaction with Chi.", "evidence": [ { "database": "UniProtKB", "id": "Q9VEB9", "url": "https://www.uniprot.org/uniprotkb/Q9VEB9" }, { "database": "PubMed", "id": "31570581", "url": "https://glygen.org/publication/PubMed/31570581" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KGW6-1", "start_pos": "69", "end_pos": "69", "site_lbl": "Leu69", "weight": 0.0, "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Impairs interaction with Chi; when associated with E-66 and A-70.", "evidence": [ { "database": "UniProtKB", "id": "Q9VEB9", "url": "https://www.uniprot.org/uniprotkb/Q9VEB9" }, { "database": "PubMed", "id": "31570581", "url": "https://glygen.org/publication/PubMed/31570581" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KGW6-1", "start_pos": "70", "end_pos": "70", "site_lbl": "Tyr70", "weight": 0.0, "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Impairs interaction with Chi; when associated with E-66 and A-69.", "evidence": [ { "database": "UniProtKB", "id": "Q9VEB9", "url": "https://www.uniprot.org/uniprotkb/Q9VEB9" }, { "database": "PubMed", "id": "31570581", "url": "https://glygen.org/publication/PubMed/31570581" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KGZ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 340, "chemical_mass": 36362.0, "gene_names": "MBD-like;3;CG8208;Dm Mbd2/3;DmMbd2/3;Dmel\\CG8208;Dmel_CG8208;MBD-like;MBD2-3;MBD2/3;MBD2;MBD3;dMBD-like;dMBD2/3;dMbD2/3", "protein_name": "", "disease": [ { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.", "url": "https://disease-ontology.org/term/DOID:7148", "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ], "weight": 0.0 }, { "disease_id": "DOID:8456", "name": "choline deficiency disease", "description": "A nutritional deficiency disease that is characterized by deficiency of choline, which has been associated with development of fatty liver, and possibly has_material_basis_in inadequate intake and exacerbated by a genetic predisposition.", "url": "https://disease-ontology.org/term/DOID:8456", "evidence": [ { "id": "8456", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8456" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "DNA methylation-dependent constitutive heterochromatin formation", "id": "GO:0006346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006346", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "NuRD complex", "id": "GO:0016581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016581", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" }, { "name": "methyl-CpG binding", "id": "GO:0008327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008327", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGZ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KH03-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH03", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH03" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 284, "chemical_mass": 31819.0, "gene_names": "Tsp96F;BcDNA:LD19727;CG6120;Dm.Tsp96F;Dmel\\CG6120;Dmel_CG6120;LD19727;Tsp96F;tsp96F", "protein_name": "Tetraspanin", "disease": [ { "disease_id": "DOID:0081149", "name": "common variable immunodeficiency 6", "description": "A common variable immunodeficiency that has_material_basis_in homozygous mutation in the CD81 gene on chromosome 11p.", "url": "https://disease-ontology.org/term/DOID:0081149", "evidence": [ { "id": "0081149", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081149" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2526", "name": "prostate adenocarcinoma", "description": "A prostate carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:2526", "evidence": [ { "id": "2526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2526" } ], "weight": 0.0 }, { "disease_id": "DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2671", "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ], "weight": 0.0 }, { "disease_id": "DOID:2893", "name": "cervix carcinoma", "description": "A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2893", "evidence": [ { "id": "2893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2893" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:3459", "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH03", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH03" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH03", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH03" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KHK1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 597, "chemical_mass": 68620.0, "gene_names": "slmb;BcDNA:GM02031;Beta-TRCP1;CG3412;Dmel\\CG3412;Dmel_CG3412;FBXW1;MENE (3R)-B;MENE(3R)-B;SLIMB;SLMB;Slimb/Beta-TRCP1;Slimb/beta-TRCP;Slimb/beta-TrCP;Slimb/betaTrCP;Slimb;Slmb;beta-TRCP;beta-TrCP;betaTrCP;crd;ica;l(3)00295;shv;slimb;slmb;wel", "protein_name": "", "disease": [ { "disease_id": "DOID:1838", "name": "Menkes disease", "description": "", "url": "https://disease-ontology.org/term/DOID:1838", "evidence": [ { "id": "1838", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1838" } ], "weight": 0.0 } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of glial cell proliferation", "id": "GO:0060253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060253", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "locomotor rhythm", "id": "GO:0045475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045475", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "establishment of epithelial cell polarity", "id": "GO:0090162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090162", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "regulation of centriole replication", "id": "GO:0046599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046599", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "regulation of establishment of cell polarity", "id": "GO:2000114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000114", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "regulation of chromosome condensation", "id": "GO:0060623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060623", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "germarium-derived female germ-line cyst encapsulation", "id": "GO:0030708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030708", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "germarium-derived female germ-line cyst formation", "id": "GO:0030727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030727", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "germarium-derived egg chamber formation", "id": "GO:0007293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007293", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "chorion-containing eggshell formation", "id": "GO:0007304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007304", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "oocyte axis specification", "id": "GO:0007309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007309", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "follicle cell of egg chamber development", "id": "GO:0030707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030707", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "follicle cell of egg chamber stalk formation", "id": "GO:0030713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030713", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "oocyte localization involved in germarium-derived egg chamber formation", "id": "GO:0030720", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030720", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "dorsal appendage formation", "id": "GO:0046843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046843", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "positive regulation of border follicle cell migration", "id": "GO:1903688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903688", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of nurse cell apoptotic process", "id": "GO:0045849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045849", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "positive regulation of protein catabolic process", "id": "GO:0045732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045732", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "regulation of proteasomal protein catabolic process", "id": "GO:0061136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061136", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of antimicrobial peptide production", "id": "GO:0002785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002785", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "positive regulation of Toll signaling pathway", "id": "GO:0045752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045752", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "negative regulation of peptidoglycan recognition protein signaling pathway", "id": "GO:0061060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061060", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "positive regulation of neuron remodeling", "id": "GO:1904801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904801", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "positive regulation of synaptonemal complex assembly", "id": "GO:1905088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905088", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "beta-catenin destruction complex binding", "id": "GO:1904713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904713", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" } ], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHK1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6M3Q9L5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 891, "chemical_mass": 99021.0, "gene_names": "PIP5K59B;CG17281;CG3682;Dmel\\CG3682;Dmel_CG3682;PI4P5K;PIP5K 59B;PIP5K59B;PIP5K;PIPK59B;dPIP5K59B;dPIP5K;dpip5k", "protein_name": "", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 5-kinase activity", "id": "GO:0016308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016308", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" }, { "name": "rhabdomere microvillus membrane", "id": "GO:0035997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035997", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" } ], "biological_process": [ { "name": "phototransduction, visible light", "id": "GO:0007603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007603", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol biosynthetic process", "id": "GO:0010513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010513", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" }, { "name": "cellular response to light stimulus", "id": "GO:0071482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071482", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" }, { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q9L5", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q9L5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A6M3Q9L5-1", "start_pos": "550", "end_pos": "550", "site_lbl": "Thr550", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 550, "start_aa": "Thr", "end_pos": 550, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr550", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7S9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7S9", "url": "https://www.uniprot.org/uniprotkb/A1Z7S9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 170, "chemical_mass": 19622.0, "gene_names": "Tsen15;BcDNA:GM04716;CG30343;Dmel\\CG30343;Dmel_CG30343;TSEN15;Tsen15", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S9", "url": "https://www.uniprot.org/uniprotkb/A1Z7S9" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S9", "url": "https://www.uniprot.org/uniprotkb/A1Z7S9" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S9", "url": "https://www.uniprot.org/uniprotkb/A1Z7S9" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S9", "url": "https://www.uniprot.org/uniprotkb/A1Z7S9" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S9", "url": "https://www.uniprot.org/uniprotkb/A1Z7S9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z6P8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6P8", "url": "https://www.uniprot.org/uniprotkb/A1Z6P8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1006, "chemical_mass": 113842.0, "gene_names": "Epac;CG15235;CG3427;CG34392;D-EPAC;D-Epac;Dm_2R:10367;Dmel\\CG34392;Dmel_CG34392;Epac;epac", "protein_name": "", "disease": [ { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of Rap protein signal transduction", "id": "GO:0032487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032487", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P8", "url": "https://www.uniprot.org/uniprotkb/A1Z6P8" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P8", "url": "https://www.uniprot.org/uniprotkb/A1Z6P8" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P8", "url": "https://www.uniprot.org/uniprotkb/A1Z6P8" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P8", "url": "https://www.uniprot.org/uniprotkb/A1Z6P8" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z6P8", "url": "https://www.uniprot.org/uniprotkb/A1Z6P8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z6P8-1", "start_pos": "650", "end_pos": "650", "site_lbl": "Thr650", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 650, "start_aa": "Thr", "end_pos": 650, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr650", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KHF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHF1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 524, "chemical_mass": 60415.0, "gene_names": "MICU3;CG4662;Dmel\\CG4662;Dmel_CG4662;MICU3;micu3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHF1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHF1" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHF1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHF1" } ], "pmid": "" }, { "name": "uniplex complex", "id": "GO:1990246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990246", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHF1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHF1" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHF1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHF1" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHF1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHF1" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium import into the mitochondrion", "id": "GO:0036444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036444", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHF1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHF1" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHF1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI51", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3003, "chemical_mass": 322066.0, "gene_names": "Bicra;Bicra;CG11873;Dmel\\CG11873;Dmel_CG11873;anon-WO0140519.162", "protein_name": "", "disease": [ { "disease_id": "DOID:0112370", "name": "Coffin-Siris syndrome 12", "description": "A Coffin-Siris syndrome characterized by global developmental delay with variably impaired intellectual development, speech and language delay, and behavioral abnormalities, such as autism or hyperactivity that has_material_basis_in heterozygous mutation in the BICRA gene on chromosome 19q13.33.", "url": "https://disease-ontology.org/term/DOID:0112370", "evidence": [ { "id": "0112370", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112370" } ], "weight": 0.0 }, { "disease_id": "DOID:1925", "name": "Coffin-Siris syndrome", "description": "An autosomal dominant intellectual developmental disorder that is characterized by mental retardation associated with coarse facial features, hypertrichosis, sparse scalp hair, and hypoplastic or absent fifth fingernails or toenails.", "url": "https://disease-ontology.org/term/DOID:1925", "evidence": [ { "id": "1925", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1925" } ], "weight": 0.0 } ], "biological_process": [ { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI51", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI51" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI51", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI51" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI51", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI51" } ], "pmid": "" } ], "cellular_component": [ { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI51", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI51" } ], "pmid": "" }, { "name": "brahma complex", "id": "GO:0035060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035060", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI51", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "1183", "end_pos": "1183", "site_lbl": "Thr1183", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1183, "start_aa": "Thr", "end_pos": 1183, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1183", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "1185", "end_pos": "1185", "site_lbl": "Thr1185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1185, "start_aa": "Thr", "end_pos": 1185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1185", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "1465", "end_pos": "1465", "site_lbl": "Thr1465", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1465, "start_aa": "Thr", "end_pos": 1465, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1465", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "1730", "end_pos": "1730", "site_lbl": "Thr1730", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1730, "start_aa": "Thr", "end_pos": 1730, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1730", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "1856", "end_pos": "1856", "site_lbl": "Thr1856", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1856, "start_aa": "Thr", "end_pos": 1856, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1856", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "2119", "end_pos": "2119", "site_lbl": "Thr2119", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2119, "start_aa": "Thr", "end_pos": 2119, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2119", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "241", "end_pos": "241", "site_lbl": "Thr241", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 241, "start_aa": "Thr", "end_pos": 241, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr241", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Thr71", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "744", "end_pos": "744", "site_lbl": "Thr744", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 744, "start_aa": "Thr", "end_pos": 744, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr744", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "770", "end_pos": "770", "site_lbl": "Thr770", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 770, "start_aa": "Thr", "end_pos": 770, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr770", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "start_pos": "975", "end_pos": "975", "site_lbl": "Thr975", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 975, "start_aa": "Thr", "end_pos": 975, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr975", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LF16-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF16", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF16" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 452, "chemical_mass": 51574.0, "gene_names": "Dmel\\CG1407;CG1407;Dmel\\CG1407;Dmel_CG1407;ZDHHC15", "protein_name": "Palmitoyltransferase", "disease": [ { "disease_id": "DOID:225", "name": "syndrome", "description": "A disease characterized by a group of signs and symptoms that occur together and characterize a particular abnormality.", "url": "https://disease-ontology.org/term/DOID:225", "evidence": [ { "id": "225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:225" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF16", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF16" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF16", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF16" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF16", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF16" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF16", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF16" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF16", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF16" } ], "pmid": "" }, { "name": "synaptic vesicle maturation", "id": "GO:0016188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016188", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF16", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF16" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBW6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBW6", "url": "https://www.uniprot.org/uniprotkb/A1ZBW6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 726, "chemical_mass": 82630.0, "gene_names": "Dmel\\CG11180;CG11180;Dmel\\CG11180;Dmel_CG11180", "protein_name": "G-patch domain-containing protein", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW6", "url": "https://www.uniprot.org/uniprotkb/A1ZBW6" } ], "pmid": "" }, { "name": "telomerase inhibitor activity", "id": "GO:0010521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010521", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW6", "url": "https://www.uniprot.org/uniprotkb/A1ZBW6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW6", "url": "https://www.uniprot.org/uniprotkb/A1ZBW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "E1JIH3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 844, "chemical_mass": 93910.0, "gene_names": "Unc-115a;CG31352;CG9489;Dmel\\CG31352;Dmel_CG31352;Dunc-115;Unc-115a;Unc-115b;anon-WO0140519.21;dunc-115;unc-115;unc-15a", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" }, { "name": "photoreceptor cell axon guidance", "id": "GO:0072499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072499", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1JIH3", "url": "https://www.uniprot.org/uniprotkb/E1JIH3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "M9MRJ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRJ1", "url": "https://www.uniprot.org/uniprotkb/M9MRJ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 984, "chemical_mass": 104194.0, "gene_names": "CG16851;CG31846;CR31846;mdcds_2231;BcDNA:GH04046;BcDNA:HL01958;CG16850;CG16851;CG31846;CG31847;CG42784;CR31846;Dm_2L:67149;Dmel\\CG42784;Dmel_CG42784;mdcds_2231", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9MRJ1", "url": "https://www.uniprot.org/uniprotkb/M9MRJ1" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "M9MRJ1", "url": "https://www.uniprot.org/uniprotkb/M9MRJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "M9MRJ1", "url": "https://www.uniprot.org/uniprotkb/M9MRJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "M9NEB2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1273, "chemical_mass": 137409.0, "gene_names": "Mbs;04;0573/06;06;0953/04;CG32156;CG5600;CG5891;DMBS;DMYPT;DMbs;Dmel\\CG32156;Dmel_CG32156;MBS;Mbs;Mypt;l(3)03802;l(3)72Dd;l(3)S005331b;l(3)S057306b;l(3)S057306;l(3)S095304;l(3)j3B4;l(3)j7A1;mbs", "protein_name": "Protein phosphatase 1 regulatory subunit 12B", "disease": [], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "myosin phosphatase regulator activity", "id": "GO:0017020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017020", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of locomotor rhythm", "id": "GO:1904059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904059", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "epidermis development", "id": "GO:0008544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008544", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "germline ring canal formation", "id": "GO:0030725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030725", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "dorsal closure", "id": "GO:0007391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007391", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "imaginal disc morphogenesis", "id": "GO:0007560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007560", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "imaginal disc-derived wing hair organization", "id": "GO:0035317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035317", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "regulation of compound eye photoreceptor development", "id": "GO:0045314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045314", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "apical cortex", "id": "GO:0045179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045179", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9NEB2", "url": "https://www.uniprot.org/uniprotkb/M9NEB2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NEB2-1", "start_pos": "1032", "end_pos": "1032", "site_lbl": "Thr1032", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1032, "start_aa": "Thr", "end_pos": 1032, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1032", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NEB2-1", "start_pos": "33", "end_pos": "33", "site_lbl": "Thr33", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NEB2-1", "start_pos": "691", "end_pos": "691", "site_lbl": "Thr691", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 691, "start_aa": "Thr", "end_pos": 691, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr691", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NEB2-1", "start_pos": "711", "end_pos": "711", "site_lbl": "Thr711", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 711, "start_aa": "Thr", "end_pos": 711, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr711", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6M3Q7H0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1170, "chemical_mass": 125656.0, "gene_names": "psq;BTB-V;BtbV;CG2368;Dmel\\CG2368;Dmel_CG2368;Lola;PSQ;Pipsqueak;Piq;Psq;eyeful;pip;psk;psq-1;psq;rum;zep", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "POZ domain binding", "id": "GO:0031208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031208", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "embryonic pattern specification", "id": "GO:0009880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009880", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "anterior/posterior axis specification, embryo", "id": "GO:0008595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008595", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "pole plasm assembly", "id": "GO:0007315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007315", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7H0", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7H0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z6Z8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1800, "chemical_mass": 208245.0, "gene_names": "didum;43CD;CG2146;Didum;DmV;Dmel\\CG2146;Dmel_CG2146;M5;MYOV;Myo1C;Myo5;MyoV43CD;MyoV;NEST:bs14c05;NMC7;didum;dmM5;myoV;soy", "protein_name": "", "disease": [ { "disease_id": "DOID:0060775", "name": "microvillus inclusion disease", "description": "A congenital diarrhea characterized by onset of intractable life-threatening watery diarrhea during infancy, lack of microvilli on the surface of enterocytes and occurrence of intracellular vacuolar structures containing microvilli that has_material_basis_in homozygous or compound heterozygous mutation in the MYO5B gene on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0060775", "evidence": [ { "id": "0060775", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060775" } ], "weight": 0.0 }, { "disease_id": "DOID:0060832", "name": "Griscelli syndrome type 1", "description": "A Griscelli syndrome characterized by silvery gray sheen of the hair, hypopigmentation of the skin and neurological impairment without immunodeficiency that has_material_basis_in mutations in the MYO5A gene on chromosome 15q21.2.", "url": "https://disease-ontology.org/term/DOID:0060832", "evidence": [ { "id": "0060832", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060832" } ], "weight": 0.0 }, { "disease_id": "DOID:0070221", "name": "progressive familial intrahepatic cholestasis", "description": "An intrahepatic cholestasis characterized by early onset of chronic unremitting cholestasis of hepatocellular origin that progresses to hepatic fibrosis, cirrhosis, and end-stage liver disease before adulthood.", "url": "https://disease-ontology.org/term/DOID:0070221", "evidence": [ { "id": "0070221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070221" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "myosin V complex", "id": "GO:0031475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031475", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "rhabdomere", "id": "GO:0016028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016028", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrion transport along microtubule", "id": "GO:0047497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047497", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "sperm individualization", "id": "GO:0007291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007291", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "anterior/posterior axis specification, embryo", "id": "GO:0008595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008595", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "rhabdomere development", "id": "GO:0042052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042052", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "positive regulation of pole plasm oskar mRNA localization", "id": "GO:0045856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045856", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "myosin light chain binding", "id": "GO:0032027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032027", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "calcium-dependent ATPase activity", "id": "GO:0030899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030899", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z6Z8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8DYB7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 816, "chemical_mass": 90485.0, "gene_names": "Dyb;CG8529;DmDYB;Dmel\\CG8529;Dmel_CG8529;Dyb", "protein_name": "", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:0060480", "name": "left ventricular noncompaction", "description": "An intrinsic cardiomyopathy characterized by distinctive (spongy) morphological appearance of the LV myocardium.", "url": "https://disease-ontology.org/term/DOID:0060480", "evidence": [ { "id": "0060480", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060480" } ], "weight": 0.0 }, { "disease_id": "DOID:0061184", "name": "myopathy with myalgia, increased serum creatine kinase, and with or without episodic rhabdomyolysis 2", "description": "A muscular disease characterized by myalgia, muscle cramps, exercise intolerance, and increased serum creatine kinase with onset between the first and fourth decades of life that has_material_basis_in heterozygous mutation in the DTNA gene on chromosome 18q12.", "url": "https://disease-ontology.org/term/DOID:0061184", "evidence": [ { "id": "0061184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061184" } ], "weight": 0.0 }, { "disease_id": "DOID:11723", "name": "Duchenne muscular dystrophy", "description": "A muscular dystrophy that has_material_basis_in X-linked mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing muscle weakness and muscle atrophy initially involving the lower extremities and eventually affecting the whole body. It affects males whereas females can be carriers. The symptoms start before the age of six and may appear at infancy.", "url": "https://disease-ontology.org/term/DOID:11723", "evidence": [ { "id": "11723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11723" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "dystrophin-associated glycoprotein complex", "id": "GO:0016010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016010", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" } ], "biological_process": [ { "name": "muscle cell cellular homeostasis", "id": "GO:0046716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046716", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "maintenance of presynaptic active zone structure", "id": "GO:0048790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048790", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "regulation of neurotransmitter secretion", "id": "GO:0046928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046928", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" }, { "name": "synaptic signaling", "id": "GO:0099536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099536", "evidence": [ { "database": "UniProtKB", "id": "A8DYB7", "url": "https://www.uniprot.org/uniprotkb/A8DYB7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B7YZT5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1364, "chemical_mass": 155371.0, "gene_names": "Pld;CG12110;Dmel\\CG12110;Dmel_CG12110;MitoPLD;PC-Pld;PLD;Pld;dPLD;dPld;phospholipase D;pld1;pld", "protein_name": "Phospholipase", "disease": [ { "disease_id": "DOID:0080633", "name": "developmental cardiac valvular defect", "description": "A physical disorder that has_material_basis_in homozygous or compound heterozygous mutation in the PLD1 gene on chromosome 3q26.", "url": "https://disease-ontology.org/term/DOID:0080633", "evidence": [ { "id": "0080633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080633" } ], "weight": 0.0 }, { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phospholipase D activity", "id": "GO:0004630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004630", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "positive regulation of Golgi vesicle fusion to target membrane", "id": "GO:0048215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048215", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "cellularization", "id": "GO:0007349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007349", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "gastrulation involving germ band extension", "id": "GO:0010004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010004", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "regulation of vesicle-mediated transport", "id": "GO:0060627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060627", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" } ], "cellular_component": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B7YZT5", "url": "https://www.uniprot.org/uniprotkb/B7YZT5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7YZT5-1", "start_pos": "506", "end_pos": "506", "site_lbl": "Thr506", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 506, "start_aa": "Thr", "end_pos": 506, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr506", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "M9MRX4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 13559, "chemical_mass": 1488354.0, "gene_names": "Ank2;Ank2;CG18025;CG18227;CG18768;CG32373;CG32375;CG32377;CG34121;CG34158;CG34416;CG42734;CG7462;CG7493;DAnk2;Dank2;Dmel\\CG42734;Dmel_CG42734;ESTS:149B10S;SP2523;ank2-L;ank2;dank2;sp2523", "protein_name": "", "disease": [ { "disease_id": "DOID:0050824", "name": "sinoatrial node disease", "description": "A heart conduction disease that is characterized by dysfunction of the impulse-generating (pacemaker) tissue located in the right atrium of the heart which generates normal sinus rhythm.", "url": "https://disease-ontology.org/term/DOID:0050824", "evidence": [ { "id": "0050824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050824" } ], "weight": 0.0 }, { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0111700", "name": "ankyrin-B-related cardiac arrhythmia", "description": "A heart disease characterized by a broad spectrum of cardiac arrhythmias including; bradycardia, sinus arrhythmia, delayed conduction/conduction block, idiopathic ventricular fibrillation, and catecholaminergic polymorphic ventricular tachycardia that has_material_basis_in heterozygous mutation in the ANK2 gene on chromosome 4q25-q26.", "url": "https://disease-ontology.org/term/DOID:0111700", "evidence": [ { "id": "0111700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111700" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:13884", "name": "sick sinus syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:13884", "evidence": [ { "id": "13884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13884" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2843", "name": "long QT syndrome", "description": "An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (TDP, a form of irregular heartbeat that originates from the ventricles).", "url": "https://disease-ontology.org/term/DOID:2843", "evidence": [ { "id": "2843", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2843" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "presynaptic periactive zone", "id": "GO:0036062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036062", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "neuron cellular homeostasis", "id": "GO:0070050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070050", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "short-term memory", "id": "GO:0007614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007614", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "positive regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045887", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" }, { "name": "negative regulation of neuromuscular synaptic transmission", "id": "GO:1900074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900074", "evidence": [ { "database": "UniProtKB", "id": "M9MRX4", "url": "https://www.uniprot.org/uniprotkb/M9MRX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "11126", "end_pos": "11126", "site_lbl": "Thr11126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11126, "start_aa": "Thr", "end_pos": 11126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11126", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "11171", "end_pos": "11171", "site_lbl": "Thr11171", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11171, "start_aa": "Thr", "end_pos": 11171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11171", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "1729", "end_pos": "1729", "site_lbl": "Ser1729", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1729, "start_aa": "Ser", "end_pos": 1729, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1729", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9MRX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9MRX4" }, { "id": "12185", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12185" }, { "id": "11334", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11334" }, { "id": "13414", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/13414" }, { "id": "12451", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12451" }, { "id": "11329", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11329" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "1785", "end_pos": "1785", "site_lbl": "Ser1785", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1785, "start_aa": "Ser", "end_pos": 1785, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1785", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9MRX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9MRX4" }, { "id": "12185", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12185" }, { "id": "11334", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11334" }, { "id": "13414", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/13414" }, { "id": "12451", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12451" }, { "id": "11329", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11329" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "2352", "end_pos": "2352", "site_lbl": "Thr2352", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2352, "start_aa": "Thr", "end_pos": 2352, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2352", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "2378", "end_pos": "2378", "site_lbl": "Thr2378", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 2378, "start_aa": "Thr", "end_pos": 2378, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2378", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9MRX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9MRX4" }, { "id": "11334", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11334" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "2385", "end_pos": "2385", "site_lbl": "Thr2385", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 2385, "start_aa": "Thr", "end_pos": 2385, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2385", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9MRX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9MRX4" }, { "id": "12185", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12185" }, { "id": "11334", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11334" }, { "id": "13414", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/13414" }, { "id": "12451", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12451" }, { "id": "11329", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11329" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "3225", "end_pos": "3225", "site_lbl": "Thr3225", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 3225, "start_aa": "Thr", "end_pos": 3225, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3225", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9MRX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9MRX4" }, { "id": "12185", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12185" }, { "id": "11334", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11334" }, { "id": "13414", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/13414" }, { "id": "12451", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12451" }, { "id": "11329", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11329" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "5472", "end_pos": "5472", "site_lbl": "Ser5472", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 5472, "start_aa": "Ser", "end_pos": 5472, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser5472", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9MRX4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9MRX4" }, { "id": "12185", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12185" }, { "id": "11334", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11334" }, { "id": "13414", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/13414" }, { "id": "12451", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12451" }, { "id": "11329", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11329" } ] } ] }, { "uniprot_canonical_ac": "M9MRX4-1", "start_pos": "880", "end_pos": "880", "site_lbl": "Thr880", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 880, "start_aa": "Thr", "end_pos": 880, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr880", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8G0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8G0", "url": "https://www.uniprot.org/uniprotkb/A1Z8G0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 595, "chemical_mass": 66674.0, "gene_names": "metro;CG13219;CG18338;CG30021;Dmel\\CG30021;Dmel_CG30021;FBgn0050021;Metro;metro;met", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z8G0", "url": "https://www.uniprot.org/uniprotkb/A1Z8G0" } ], "pmid": "" }, { "name": "subsynaptic reticulum", "id": "GO:0071212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071212", "evidence": [ { "database": "UniProtKB", "id": "A1Z8G0", "url": "https://www.uniprot.org/uniprotkb/A1Z8G0" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A1Z8G0", "url": "https://www.uniprot.org/uniprotkb/A1Z8G0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z8G0", "url": "https://www.uniprot.org/uniprotkb/A1Z8G0" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A1Z8G0", "url": "https://www.uniprot.org/uniprotkb/A1Z8G0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "A1Z8G0", "url": "https://www.uniprot.org/uniprotkb/A1Z8G0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B7Z0E5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1647, "chemical_mass": 188661.0, "gene_names": "mfr;CG5747;Dmel\\CG5747;Dmel_CG5747;Otoferlin;mfr", "protein_name": "", "disease": [ { "disease_id": "DOID:0070199", "name": "Miyoshi muscular dystrophy 1", "description": "A Miyoshi muscular dystrophy that has_material_basis_in mutation in the DYSF gene on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0070199", "evidence": [ { "id": "0070199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070199" } ], "weight": 0.0 }, { "disease_id": "DOID:0110276", "name": "autosomal recessive limb-girdle muscular dystrophy type 2B", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding the skeletal muscle protein dysferlin (DYSF) on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0110276", "evidence": [ { "id": "0110276", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110276" } ], "weight": 0.0 }, { "disease_id": "DOID:0110535", "name": "autosomal recessive nonsyndromic deafness 9", "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with usually severe to profound, stable hearing loss and has_material_basis_in mutation in the OTOF gene on chromosome 2p23.", "url": "https://disease-ontology.org/term/DOID:0110535", "evidence": [ { "id": "0110535", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110535" } ], "weight": 0.0 }, { "disease_id": "DOID:0111187", "name": "distal myopathy with anterior tibial onset", "description": "A distal myopathy that is characterized by onset at 14-28 years of age starting first in the anterior tibial muscles and involving both upper and lower proximal muscles that has_material_basis_in homozygous mutation in the gene encoding dysferlin (DYSF) on chromosome 2p13.", "url": "https://disease-ontology.org/term/DOID:0111187", "evidence": [ { "id": "0111187", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111187" } ], "weight": 0.0 }, { "disease_id": "DOID:11720", "name": "distal myopathy", "description": "A muscular dystrophy that is characterized by predominant weakness and atrophy beginning in the feet and/or hands.", "url": "https://disease-ontology.org/term/DOID:11720", "evidence": [ { "id": "11720", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11720" } ], "weight": 0.0 }, { "disease_id": "DOID:11724", "name": "limb-girdle muscular dystrophy", "description": "A muscular dystrophy that is characterized by weakening of the muscles of the hip and shoulders which comprise the limb girdle muscles.", "url": "https://disease-ontology.org/term/DOID:11724", "evidence": [ { "id": "11724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11724" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:14735", "name": "hereditary angioedema", "description": "An angioedema that is characterized by recurrent episodes of severe swelling of the skin and mucous membranes.", "url": "https://disease-ontology.org/term/DOID:14735", "evidence": [ { "id": "14735", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14735" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "biological_process": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" }, { "name": "synaptic vesicle exocytosis", "id": "GO:0016079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016079", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" }, { "name": "egg activation", "id": "GO:0007343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007343", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" }, { "name": "sperm plasma membrane disassembly", "id": "GO:0035045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035045", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" }, { "name": "chorion-containing eggshell pattern formation", "id": "GO:0030381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030381", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" }, { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E5", "url": "https://www.uniprot.org/uniprotkb/B7Z0E5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7Z0E5-1", "start_pos": "282", "end_pos": "282", "site_lbl": "Thr282", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 282, "start_aa": "Thr", "end_pos": 282, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8JQV3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JQV3", "url": "https://www.uniprot.org/uniprotkb/A8JQV3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 882, "chemical_mass": 96405.0, "gene_names": "Dmel\\CG17816;CG17816;Dmel\\CG17816;Dmel_CG17816", "protein_name": "Nuclear protein MDM1", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8JQV3", "url": "https://www.uniprot.org/uniprotkb/A8JQV3" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A8JQV3", "url": "https://www.uniprot.org/uniprotkb/A8JQV3" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A8JQV3", "url": "https://www.uniprot.org/uniprotkb/A8JQV3" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A8JQV3", "url": "https://www.uniprot.org/uniprotkb/A8JQV3" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of centriole replication", "id": "GO:0046600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046600", "evidence": [ { "database": "UniProtKB", "id": "A8JQV3", "url": "https://www.uniprot.org/uniprotkb/A8JQV3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "M9NFI9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2148, "chemical_mass": 233441.0, "gene_names": "Spn;BcDNA:GM16129;CG16757;Dmel\\CG16757;Dmel_CG16757;E62;EL62;Spn;c62E-5;l(3)06911;spn", "protein_name": "Neurabin-1", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "apical cortex", "id": "GO:0045179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045179", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "neurexin family protein binding", "id": "GO:0042043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042043", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "negative regulation of presynaptic active zone assembly", "id": "GO:1905519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905519", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "M9NFI9", "url": "https://www.uniprot.org/uniprotkb/M9NFI9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NFI9-1", "start_pos": "2010", "end_pos": "2010", "site_lbl": "Thr2010", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2010, "start_aa": "Thr", "end_pos": 2010, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2010", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "M9NEH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NEH9", "url": "https://www.uniprot.org/uniprotkb/M9NEH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 573, "chemical_mass": 58090.0, "gene_names": "mub;CG7437;Dmel\\CG7437;Dmel_CG7437;MRE17;MUB;Mub;anon-WO0172774.33;anon-WO0172774.35;anon-WO0172774.36;anon-WO0172774.37;l(3)04093;l(3)j6B10;l(3)j8B3;mub", "protein_name": "", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "M9NEH9", "url": "https://www.uniprot.org/uniprotkb/M9NEH9" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "M9NEH9", "url": "https://www.uniprot.org/uniprotkb/M9NEH9" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "M9NEH9", "url": "https://www.uniprot.org/uniprotkb/M9NEH9" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "M9NEH9", "url": "https://www.uniprot.org/uniprotkb/M9NEH9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9NEH9", "url": "https://www.uniprot.org/uniprotkb/M9NEH9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9NEH9", "url": "https://www.uniprot.org/uniprotkb/M9NEH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NEH9-1", "start_pos": "412", "end_pos": "412", "site_lbl": "Thr412", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 412, "start_aa": "Thr", "end_pos": 412, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr412", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0S0WPM5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WPM5", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WPM5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 336, "chemical_mass": 36938.0, "gene_names": "Dmel\\CG13685;CG13685;Dmel\\CG13685;Dmel_CG13685", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KHJ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 907, "chemical_mass": 101468.0, "gene_names": "Grik;CG5621;CT17756;DKaiRIC;DmelCG5621;Dmel\\CG5621;Dmel_CG5621;Grik;KaiR1C;anon-WO0138359.5", "protein_name": "", "disease": [ { "disease_id": "DOID:0081182", "name": "autosomal recessive intellectual developmental disorder 6", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the ionotropic glutamate receptor-6 gene (GRIK2) on chromosome 6q16.", "url": "https://disease-ontology.org/term/DOID:0081182", "evidence": [ { "id": "0081182", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081182" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1825", "name": "childhood absence epilepsy", "description": "A childhood electroclinical syndrome that is characterized by brief and frequent absence seizures in children with age of onset between four and ten years.", "url": "https://disease-ontology.org/term/DOID:1825", "evidence": [ { "id": "1825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1825" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "kainate selective glutamate receptor activity", "id": "GO:0015277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015277", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" }, { "name": "glutamate receptor activity", "id": "GO:0008066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008066", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of synaptic activity", "id": "GO:0060025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060025", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KHJ0-1", "start_pos": "185", "end_pos": "185", "site_lbl": "Thr185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 185, "start_aa": "Thr", "end_pos": 185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr185", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "H9XVP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3186, "chemical_mass": 360416.0, "gene_names": "unc-13;CG2999;DUNC-13;Dmel\\CG2999;Dmel_CG2999;Dunc-13;Dunc13;Munc-13/UNC-13;Munc-13;UNC-13-B;UNC-13;UNC13A;UNC13B;Unc-13;Unc13A;Unc13B;Unc13;dUNC-13;dUnc-13;drunc13;dunc-13;l(4)ry16;unc-13;unc13A;unc", "protein_name": "", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "diacylglycerol binding", "id": "GO:0019992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019992", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "syntaxin-1 binding", "id": "GO:0017075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017075", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" } ], "cellular_component": [ { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" } ], "biological_process": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "synaptic vesicle exocytosis", "id": "GO:0016079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016079", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "synaptic vesicle docking", "id": "GO:0016081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016081", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "dense core granule priming", "id": "GO:0061789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061789", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" }, { "name": "synaptic vesicle tethering involved in synaptic vesicle exocytosis", "id": "GO:0099069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099069", "evidence": [ { "database": "UniProtKB", "id": "H9XVP2", "url": "https://www.uniprot.org/uniprotkb/H9XVP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "H9XVP2-1", "start_pos": "870", "end_pos": "870", "site_lbl": "Thr870", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 870, "start_aa": "Thr", "end_pos": 870, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr870", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6H2EF03-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EF03", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EF03" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 397, "chemical_mass": 44708.0, "gene_names": "Dmel\\CG5768;CG5768;Dmel_CG5768", "protein_name": "Membrane-associated protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KHD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 740, "chemical_mass": 80023.0, "gene_names": "Octalpha2R;CG18208;DmOctalpha2R;Dmel\\CG18208;Dmel_CG18208;Octalpha2R;Octalpha", "protein_name": "", "disease": [ { "disease_id": "DOID:0050440", "name": "familial partial lipodystrophy", "description": "A partial lipodystrophy characterized by abnormal subcutaneous adipose tissue distribution beginning in late childhood or early adult life.", "url": "https://disease-ontology.org/term/DOID:0050440", "evidence": [ { "id": "0050440", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050440" } ], "weight": 0.0 }, { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:2560", "name": "morphine dependence", "description": "An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2560", "evidence": [ { "id": "2560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2560" } ], "weight": 0.0 }, { "disease_id": "DOID:302", "name": "substance abuse", "description": "A substance-related disorder that involves a maladaptive pattern of substance use leading to significant impairment in functioning.", "url": "https://disease-ontology.org/term/DOID:302", "evidence": [ { "id": "302", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:302" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHD0" } ], "pmid": "" } ], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHD0" } ], "pmid": "" }, { "name": "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "id": "GO:0007193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007193", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHD0" } ], "pmid": "" } ], "molecular_function": [ { "name": "heterotrimeric G-protein binding", "id": "GO:0032795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032795", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHD0" } ], "pmid": "" }, { "name": "G protein-coupled amine receptor activity", "id": "GO:0008227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008227", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHD0" } ], "pmid": "" }, { "name": "octopamine receptor activity", "id": "GO:0004989", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004989", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHD0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KHD0-1", "start_pos": "487", "end_pos": "487", "site_lbl": "Thr487", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 487, "start_aa": "Thr", "end_pos": 487, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr487", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KH20-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 775, "chemical_mass": 85245.0, "gene_names": "nerfin-2;CG12809;Dmel\\CG12809;Dmel_CG12809;Nerfin;nerfin-2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" }, { "name": "regulation of cell cycle process", "id": "GO:0010564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010564", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH20", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH20" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KH20-1", "start_pos": "100", "end_pos": "100", "site_lbl": "Thr100", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 100, "start_aa": "Thr", "end_pos": 100, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr100", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KH20-1", "start_pos": "96", "end_pos": "96", "site_lbl": "Thr96", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 96, "start_aa": "Thr", "end_pos": 96, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr96", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B7YZX6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZX6", "url": "https://www.uniprot.org/uniprotkb/B7YZX6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1406, "chemical_mass": 153643.0, "gene_names": "Dmel\\CG10600;CG10600;Dmel\\CG10600;Dmel_CG10600", "protein_name": "Round spermatid basic protein 1-like protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B7YZX6", "url": "https://www.uniprot.org/uniprotkb/B7YZX6" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone H4K20 demethylase activity", "id": "GO:0035575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035575", "evidence": [ { "database": "UniProtKB", "id": "B7YZX6", "url": "https://www.uniprot.org/uniprotkb/B7YZX6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7YZX6-1", "start_pos": "145", "end_pos": "145", "site_lbl": "Thr145", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 145, "start_aa": "Thr", "end_pos": 145, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr145", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "B7YZX6-1", "start_pos": "87", "end_pos": "87", "site_lbl": "Thr87", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 87, "start_aa": "Thr", "end_pos": 87, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr87", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6H2EJG3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4065, "chemical_mass": 466027.0, "gene_names": "Dhc36C;CG5526;DHC7A;DHC;Dhc 36C;Dhc36C;Dhc36c;Dhc;Dmel\\CG5526;Dmel_CG5526;dhc", "protein_name": "Dynein axonemal heavy chain 7", "disease": [ { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "axonemal dynein complex", "id": "GO:0005858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005858", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "inner dynein arm", "id": "GO:0036156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036156", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJG3", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJG3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A6H2EJG3-1", "start_pos": "1969", "end_pos": "1969", "site_lbl": "Thr1969", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1969, "start_aa": "Thr", "end_pos": 1969, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1969", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EJG3-1", "start_pos": "2093", "end_pos": "2093", "site_lbl": "Thr2093", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2093, "start_aa": "Thr", "end_pos": 2093, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2093", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EJG3-1", "start_pos": "2159", "end_pos": "2159", "site_lbl": "Thr2159", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2159, "start_aa": "Thr", "end_pos": 2159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2159", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EJG3-1", "start_pos": "2547", "end_pos": "2547", "site_lbl": "Thr2547", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2547, "start_aa": "Thr", "end_pos": 2547, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2547", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "E1JI40-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 555, "chemical_mass": 63092.0, "gene_names": "verm;CG8756;DmCDA2;Dmel\\CG8756;Dmel_CG8756;LCBP1;N63;Verm;hlm;l(3)76BDx;verm", "protein_name": "", "disease": [], "biological_process": [ { "name": "trachea morphogenesis", "id": "GO:0060439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060439", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "visual behavior", "id": "GO:0007632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007632", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "dorsal trunk growth, open tracheal system", "id": "GO:0035001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035001", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "regulation of tube length, open tracheal system", "id": "GO:0035159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035159", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "adult chitin-based cuticle development", "id": "GO:0008365", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008365", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "larval chitin-based cuticle development", "id": "GO:0008363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008363", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "E1JI40", "url": "https://www.uniprot.org/uniprotkb/E1JI40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E1JI40-1", "start_pos": "259", "end_pos": "259", "site_lbl": "Thr259", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 259, "start_aa": "Thr", "end_pos": 259, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr259", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "E1JI40", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/E1JI40" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0C4DHC8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHC8", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHC8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 564, "chemical_mass": 63039.0, "gene_names": "Aldh-III;ALDH-III;ALDH;Aldh-III;AldhIII;CG11140;CT41571;Dhap;Dmel\\CG11140;Dmel_CG11140;FALDH;l(2)03610", "protein_name": "", "disease": [ { "disease_id": "DOID:14501", "name": "Sjogren-Larsson syndrome", "description": "A syndrome that is characterized by ichthyosis, mental retardation, spastic paraparesis, macular dystrophy, and leukoencephalopathy, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the aldehyde dehydrogenase 3 family member A2 (ALDH3A2) gene, which encodes fatty aldehyde dehydrogenase, on chromosome 17p11.", "url": "https://disease-ontology.org/term/DOID:14501", "evidence": [ { "id": "14501", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14501" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 } ], "biological_process": [ { "name": "aldehyde metabolic process", "id": "GO:0006081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006081", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHC8", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHC8" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor", "id": "GO:0016620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016620", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHC8", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHC8" } ], "pmid": "" }, { "name": "aldehyde dehydrogenase (NAD+) activity", "id": "GO:0004029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004029", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHC8", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHC8" } ], "pmid": "" }, { "name": "farnesal dehydrogenase (NAD+) activity", "id": "GO:0120553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120553", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHC8", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHC8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHC8", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHC8" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHC8", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHC8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHC8", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8DYA3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3131, "chemical_mass": 336605.0, "gene_names": "tou;CG10897;Dm Tou;Dmel\\CG10897;Dmel_CG10897;EP(2)0622;EP0622;EP622;TIP5;TOU;Tou;VI;anon-48Ad;gene VI;tou", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" } ], "biological_process": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" }, { "name": "negative regulation of transcription elongation by RNA polymerase I", "id": "GO:2001208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001208", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" } ], "cellular_component": [ { "name": "ISWI-type complex", "id": "GO:0031010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031010", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A8DYA3", "url": "https://www.uniprot.org/uniprotkb/A8DYA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "2926", "end_pos": "2926", "site_lbl": "Thr2926", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2926, "start_aa": "Thr", "end_pos": 2926, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2926", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "2936", "end_pos": "2936", "site_lbl": "Thr2936", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2936, "start_aa": "Thr", "end_pos": 2936, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2936", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "2940", "end_pos": "2940", "site_lbl": "Thr2940", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2940, "start_aa": "Thr", "end_pos": 2940, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2940", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "2947", "end_pos": "2947", "site_lbl": "Thr2947", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2947, "start_aa": "Thr", "end_pos": 2947, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2947", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "658", "end_pos": "658", "site_lbl": "Ser658", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 658, "start_aa": "Ser", "end_pos": 658, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser658", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DYA3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DYA3" } ] } ] }, { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "664", "end_pos": "664", "site_lbl": "Thr664", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 664, "start_aa": "Thr", "end_pos": 664, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr664", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DYA3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DYA3" } ] } ] }, { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "665", "end_pos": "665", "site_lbl": "Thr665", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 665, "start_aa": "Thr", "end_pos": 665, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr665", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DYA3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DYA3" } ] } ] }, { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Ser666", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 666, "start_aa": "Ser", "end_pos": 666, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser666", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DYA3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DYA3" } ] } ] }, { "uniprot_canonical_ac": "A8DYA3-1", "start_pos": "696", "end_pos": "696", "site_lbl": "Ser696", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 696, "start_aa": "Ser", "end_pos": 696, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser696", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DYA3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DYA3" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B9A0M5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 133, "chemical_mass": 15281.0, "gene_names": "Cby;CBY;CG13415;Cby;Dmel\\CG13415;Dmel_CG13415;cby", "protein_name": "", "disease": [ { "disease_id": "DOID:10754", "name": "otitis media", "description": "A otitis which involves inflammation of the middle ear.", "url": "https://disease-ontology.org/term/DOID:10754", "evidence": [ { "id": "10754", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10754" } ], "weight": 0.0 }, { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ciliary basal body-plasma membrane docking", "id": "GO:0097711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097711", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "intraciliary transport involved in cilium assembly", "id": "GO:0035735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035735", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "protein localization to ciliary transition zone", "id": "GO:1904491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904491", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "ciliary transition zone assembly", "id": "GO:1905349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905349", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" } ], "cellular_component": [ { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "distal portion of axoneme", "id": "GO:0120135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120135", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" }, { "name": "ciliary cap", "id": "GO:0061822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061822", "evidence": [ { "database": "UniProtKB", "id": "B9A0M5", "url": "https://www.uniprot.org/uniprotkb/B9A0M5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LGJ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGJ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 537, "chemical_mass": 60627.0, "gene_names": "Gpat4;4;CG3209;DmGPAT3/4;Dmel\\CG3209;Dmel_CG3209;GPAT4;GPAT;Gpat4;dGPAT4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGJ9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGJ9" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGJ9" } ], "pmid": "" } ], "molecular_function": [ { "name": "glycerol-3-phosphate O-acyltransferase activity", "id": "GO:0004366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004366", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8JR01-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JR01", "url": "https://www.uniprot.org/uniprotkb/A8JR01" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3090, "chemical_mass": 343124.0, "gene_names": "kmr;CG14365;CG14366;CG34383;CG9322;Dm_3R:52023;Dmel\\CG34383;Dmel_CG34383;PLEKHA4;kmr", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8JR01", "url": "https://www.uniprot.org/uniprotkb/A8JR01" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JR01", "url": "https://www.uniprot.org/uniprotkb/A8JR01" } ], "pmid": "" }, { "name": "extrinsic component of cytoplasmic side of plasma membrane", "id": "GO:0031234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031234", "evidence": [ { "database": "UniProtKB", "id": "A8JR01", "url": "https://www.uniprot.org/uniprotkb/A8JR01" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "A8JR01", "url": "https://www.uniprot.org/uniprotkb/A8JR01" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of establishment of planar polarity", "id": "GO:0090175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090175", "evidence": [ { "database": "UniProtKB", "id": "A8JR01", "url": "https://www.uniprot.org/uniprotkb/A8JR01" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JR01-1", "start_pos": "1185", "end_pos": "1185", "site_lbl": "Thr1185", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1185, "start_aa": "Thr", "end_pos": 1185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1185", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8JR01-1", "start_pos": "1431", "end_pos": "1431", "site_lbl": "Thr1431", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1431, "start_aa": "Thr", "end_pos": 1431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1431", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8JR01-1", "start_pos": "1433", "end_pos": "1433", "site_lbl": "Thr1433", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1433, "start_aa": "Thr", "end_pos": 1433, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1433", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8JR01-1", "start_pos": "328", "end_pos": "328", "site_lbl": "Thr328", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 328, "start_aa": "Thr", "end_pos": 328, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr328", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8JR01-1", "start_pos": "511", "end_pos": "511", "site_lbl": "Thr511", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 511, "start_aa": "Thr", "end_pos": 511, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr511", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A4D6K4L3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4L3", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4L3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 613, "chemical_mass": 69073.0, "gene_names": "Patsas;CG6618;Dmel\\CG6618;Dmel_CG6618;Patsas", "protein_name": "Palmitoyltransferase", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4L3", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4L3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4L3", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4L3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4L3", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4L3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0S0WNI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WNI0", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WNI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 596, "chemical_mass": 68451.0, "gene_names": "CG14538;CG14538;CG46025;CG7196;Dmel\\CG46025;Dmel_CG46025", "protein_name": "DNA double-strand break repair Rad50 ATPase", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0S0WNI0-1", "start_pos": "21", "end_pos": "21", "site_lbl": "Thr21", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8W8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1983, "chemical_mass": 220591.0, "gene_names": "garz;ARF1GEF;ArfGEF;CG 8487;CG8487;Dmel\\CG8487;Dmel_CG8487;GBF1;GEF;Garz;ang;garz", "protein_name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "disease": [ { "disease_id": "DOID:0110202", "name": "Charcot-Marie-Tooth disease dominant intermediate A", "description": "A Charcot-Marie-Tooth disease intermediate type that has_material_basis_in variation in the region 10q24.1-q25.1.", "url": "https://disease-ontology.org/term/DOID:0110202", "evidence": [ { "id": "0110202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110202" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "Golgi cis cisterna", "id": "GO:0000137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000137", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "secretion by cell", "id": "GO:0032940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032940", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "salivary gland development", "id": "GO:0007431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007431", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "epithelial cell development", "id": "GO:0002064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002064", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "endomembrane system organization", "id": "GO:0010256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010256", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "lumen formation, open tracheal system", "id": "GO:0035149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035149", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "ARF protein signal transduction", "id": "GO:0032011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032011", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "positive regulation of endocytosis", "id": "GO:0045807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045807", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "regulation of tube diameter, open tracheal system", "id": "GO:0035158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035158", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A1Z8W8", "url": "https://www.uniprot.org/uniprotkb/A1Z8W8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z8W8-1", "start_pos": "1711", "end_pos": "1711", "site_lbl": "Thr1711", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1711, "start_aa": "Thr", "end_pos": 1711, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1711", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8W8-1", "start_pos": "1958", "end_pos": "1958", "site_lbl": "Thr1958", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1958, "start_aa": "Thr", "end_pos": 1958, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1958", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9Q2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q2", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 200, "chemical_mass": 22732.0, "gene_names": "Obp50a;CG30067;DmelObp50a;Dmel\\CG30067;Dmel_CG30067;Obp50a;anon-AE003814.2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q2", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q2" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q2", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q2" } ], "pmid": "" } ], "molecular_function": [ { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q2", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A4UZL3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1141, "chemical_mass": 127910.0, "gene_names": "Ehbp1;2R11;CG15609;Dmel\\CG15609;Dmel_CG15609;EHBP1;Ehbp1;dEHBP-1;dEHBP1;ehbp1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "basement membrane constituent secretion", "id": "GO:0061864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061864", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "basolateral protein secretion", "id": "GO:0110010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110010", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "regulation of basement membrane organization", "id": "GO:0110011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110011", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" }, { "name": "sensory organ precursor cell division", "id": "GO:0045035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045035", "evidence": [ { "database": "UniProtKB", "id": "A4UZL3", "url": "https://www.uniprot.org/uniprotkb/A4UZL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "D1YSG0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 8933, "chemical_mass": 1000078.0, "gene_names": "bt;39c-18;Bt;CG10285;CG1479;CG32019;CT3598;CT8086;Dmel\\CG32019;Dmel_CG32019;Prj;bt;l(2)23;l(2)2;l(4)102CDa;l(4)21;l(4)23;l(4)2;l(4)37;l(4)38;l(4)PT-2;projectin;titin", "protein_name": "", "disease": [ { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0081341", "name": "congenital myopathy 5", "description": "A congenital myopathy that is characterized by the onset of muscle weakness in infancy manifest as neonatal hypotonia, delayed motor development, and often distal contractures and that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding titin (TTN) on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0081341", "evidence": [ { "id": "0081341", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081341" } ], "weight": 0.0 }, { "disease_id": "DOID:0110283", "name": "autosomal recessive limb-girdle muscular dystrophy type 2J", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous mutation in the titin gene (TTN).", "url": "https://disease-ontology.org/term/DOID:0110283", "evidence": [ { "id": "0110283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110283" } ], "weight": 0.0 }, { "disease_id": "DOID:0110315", "name": "hypertrophic cardiomyopathy 9", "description": "A familial hypertrophic cardiomyopathy that has_material_basis_in heterozygous mutation in the TTN gene on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0110315", "evidence": [ { "id": "0110315", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110315" } ], "weight": 0.0 }, { "disease_id": "DOID:0110430", "name": "dilated cardiomyopathy 1G", "description": "A dilated cardiomyopathy that has_material_basis_in mutation in the TTN gene on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0110430", "evidence": [ { "id": "0110430", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110430" } ], "weight": 0.0 }, { "disease_id": "DOID:0111078", "name": "tibial muscular dystrophy", "description": "A distal myopathy that is characterized by autosomal dominant inheritance of late-onset muscular dystrophy beginning in the anterior compartment of the legs that has_material_basis_in heterozygous mutation in the gene encoding the giant skeletal muscle protein titin (TTN) on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0111078", "evidence": [ { "id": "0111078", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111078" } ], "weight": 0.0 }, { "disease_id": "DOID:0111188", "name": "myofibrillar myopathy 9", "description": "A myofibrillar myopathy characterized by adult onset of slowly progressive muscle weakness involving the diaphragm and resulting in respiratory insufficiency that has_material_basis_in heterozygous mutation in the TTN gene on chromosome 2q31.", "url": "https://disease-ontology.org/term/DOID:0111188", "evidence": [ { "id": "0111188", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111188" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of developmental process", "id": "GO:0050793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050793", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "muscle thin filament assembly", "id": "GO:0071689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071689", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "regulation of multicellular organismal process", "id": "GO:0051239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051239", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" } ], "cellular_component": [ { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "D1YSG0", "url": "https://www.uniprot.org/uniprotkb/D1YSG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "D1YSG0-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Thr258", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 258, "start_aa": "Thr", "end_pos": 258, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr258", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "D1YSG0-1", "start_pos": "4967", "end_pos": "4967", "site_lbl": "Thr4967", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4967, "start_aa": "Thr", "end_pos": 4967, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4967", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "D1YSG0-1", "start_pos": "6194", "end_pos": "6194", "site_lbl": "Thr6194", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6194, "start_aa": "Thr", "end_pos": 6194, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6194", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8DYY1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYY1", "url": "https://www.uniprot.org/uniprotkb/A8DYY1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 554, "chemical_mass": 64270.0, "gene_names": "CG9524;Dmel\\CG31886;anon-WO0172774.161;CG31886;CG9524;Dmel\\CG31886;Dmel_CG31886;anon-WO0172774.159;anon-WO0172774.161", "protein_name": "E3 ubiquitin-protein ligase APD1-4 middle domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8JNS4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 635, "chemical_mass": 68856.0, "gene_names": "stv;CG10745;CG14108;CG32130;Dmel\\CG32130;Dmel_CG32130;GH04349;Stv;cg32130;dBAG3;l(3)00543;stv", "protein_name": "", "disease": [ { "disease_id": "DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle.", "url": "https://disease-ontology.org/term/DOID:0050700", "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ], "weight": 0.0 }, { "disease_id": "DOID:0051042", "name": "autosomal dominant distal hereditary motor neuronopathy 15", "description": "An autosomal dominant distal hereditary motor neuronopathy that is characterized by adult onset of slowly progressive distal weakness and atrophy of the lower limbs associated with absent reflexes and that has_material_basis_in heterozygous mutation in the BAG3 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0051042", "evidence": [ { "id": "0051042", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051042" } ], "weight": 0.0 }, { "disease_id": "DOID:0051043", "name": "Charcot-Marie-Tooth disease axonal type 2JJ", "description": "A Charcot-Marie-Tooth disease type 2 that is characterized by adult onset of distal sensory impairment and distal muscle weakness and atrophy predominantly affecting the lower limbs and that has_material_basis_in heterozygous mutation in the BAG3 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0051043", "evidence": [ { "id": "0051043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051043" } ], "weight": 0.0 }, { "disease_id": "DOID:0080097", "name": "myofibrillar myopathy 6", "description": "A myofibrillar myopathy that is characterized by onset in the first decade of progressive generalized and proximal muscle weakness, respiratory insufficiency, cardiomyopathy, and skeletal deformities related to muscle weakness and that has_material_basis_in heterozygous mutation in the BAG3 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0080097", "evidence": [ { "id": "0080097", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080097" } ], "weight": 0.0 }, { "disease_id": "DOID:0110448", "name": "dilated cardiomyopathy 1HH", "description": "A dilated cardiomyopathy that has_material_basis_in mutation in the BAG3 gene on chromosome 10q26.11.", "url": "https://disease-ontology.org/term/DOID:0110448", "evidence": [ { "id": "0110448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110448" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" }, { "name": "heat shock protein binding", "id": "GO:0031072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031072", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A8JNS4", "url": "https://www.uniprot.org/uniprotkb/A8JNS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JNS4-1", "start_pos": "242", "end_pos": "242", "site_lbl": "Thr242", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 242, "start_aa": "Thr", "end_pos": 242, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr242", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "M9MSL4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1065, "chemical_mass": 123763.0, "gene_names": "Cep135;BLD10;Bld-10;Bld10p;Bld10;CEP135;CG17081;Cep135/bld10;Cep135;DBld10;DCep135/Bld10;DCep135;DmBLD10;Dmel\\CG17081;Dmel_CG17081;bld10;dbld10", "protein_name": "", "disease": [ { "disease_id": "DOID:0070282", "name": "primary autosomal recessive microcephaly 8", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the CEP135 gene on chromosome 4q.", "url": "https://disease-ontology.org/term/DOID:0070282", "evidence": [ { "id": "0070282", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070282" } ], "weight": 0.0 }, { "disease_id": "DOID:0111924", "name": "spermatogenic failure 26", "description": "A spermatogenic failure due to acephalic spermatozoa that is characterized by acephalic spermatozoa due to breakage at the midpiece of the sperm that has_material_basis_in homozygous or compound heterozygous mutation in the TSGA10 gene on chromosome 2q11.2.", "url": "https://disease-ontology.org/term/DOID:0111924", "evidence": [ { "id": "0111924", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111924" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "asymmetric neuroblast division", "id": "GO:0055059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055059", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "mitotic centrosome separation", "id": "GO:0007100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007100", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "M9MSL4", "url": "https://www.uniprot.org/uniprotkb/M9MSL4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9MSL4-1", "start_pos": "491", "end_pos": "491", "site_lbl": "Thr491", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 491, "start_aa": "Thr", "end_pos": 491, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr491", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B7YZW3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZW3", "url": "https://www.uniprot.org/uniprotkb/B7YZW3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2064, "chemical_mass": 223201.0, "gene_names": "mtgo;CG13260;CG13261;CG31738;CG42389;CG4668;CT15043;CT15049;Dmel\\CG42389;Dmel_CG42389;anon-EST:Liang-1.16;clone 1.16;mtgo", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B7YZW3", "url": "https://www.uniprot.org/uniprotkb/B7YZW3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7YZW3-1", "start_pos": "1876", "end_pos": "1876", "site_lbl": "Thr1876", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1876, "start_aa": "Thr", "end_pos": 1876, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1876", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "B7YZW3-1", "start_pos": "432", "end_pos": "432", "site_lbl": "Thr432", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 432, "start_aa": "Thr", "end_pos": 432, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr432", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "M9MRW9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRW9", "url": "https://www.uniprot.org/uniprotkb/M9MRW9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 161, "chemical_mass": 19081.0, "gene_names": "Dmel\\CG42654;CG42654;Dmel\\CG42654;Dmel_CG42654", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0S0WP14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 811, "chemical_mass": 88050.0, "gene_names": "caps;BcDNA:LD07388;CAPS;CG11282;CT31495;Caps;Dmel\\CG11282;Dmel_CG11282;caps;l(3)02937;l(3)rM632", "protein_name": "", "disease": [], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "larval salivary gland morphogenesis", "id": "GO:0007436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007436", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "branch fusion, open tracheal system", "id": "GO:0035147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035147", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "photoreceptor cell axon guidance", "id": "GO:0072499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072499", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" } ], "cellular_component": [ { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" }, { "name": "muscle cell projection", "id": "GO:0036194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036194", "evidence": [ { "database": "UniProtKB", "id": "A0A0S0WP14", "url": "https://www.uniprot.org/uniprotkb/A0A0S0WP14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0S0WP14-1", "start_pos": "711", "end_pos": "711", "site_lbl": "Thr711", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 711, "start_aa": "Thr", "end_pos": 711, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr711", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0S0WP14-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Thr713", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 713, "start_aa": "Thr", "end_pos": 713, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr713", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0S0WP14-1", "start_pos": "768", "end_pos": "768", "site_lbl": "Thr768", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 768, "start_aa": "Thr", "end_pos": 768, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr768", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8DYW8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYW8", "url": "https://www.uniprot.org/uniprotkb/A8DYW8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 959, "chemical_mass": 104862.0, "gene_names": "RapGAP1;CG13789;CG13790;CG13791;CG33529;CG34374;CG44086;CG6682;Dmel\\CG44086;Dmel_CG44086;FBpp0111515;Q9VM02_DROME;RapGAP1;RapGAP;RapGap1;Rapgap1;rapGAP1;rapgap1;rapgap", "protein_name": "", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 }, { "disease_id": "DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland.", "url": "https://disease-ontology.org/term/DOID:3969", "evidence": [ { "id": "3969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3969" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A8DYW8", "url": "https://www.uniprot.org/uniprotkb/A8DYW8" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A8DYW8", "url": "https://www.uniprot.org/uniprotkb/A8DYW8" } ], "pmid": "" } ], "cellular_component": [ { "name": "germ plasm", "id": "GO:0060293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060293", "evidence": [ { "database": "UniProtKB", "id": "A8DYW8", "url": "https://www.uniprot.org/uniprotkb/A8DYW8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8DYW8-1", "start_pos": "234", "end_pos": "234", "site_lbl": "Thr234", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 234, "start_aa": "Thr", "end_pos": 234, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr234", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DYW8-1", "start_pos": "671", "end_pos": "671", "site_lbl": "Thr671", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 671, "start_aa": "Thr", "end_pos": 671, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr671", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B7Z0R3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0R3", "url": "https://www.uniprot.org/uniprotkb/B7Z0R3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 500, "chemical_mass": 53713.0, "gene_names": "CG14525;CG31046;CG14522;CG14524;CG14525;CG31046;CG33203;Dmel\\CG33203;Dmel_CG33203", "protein_name": "Progestin and adipoQ receptor family member 4", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7Z0R3", "url": "https://www.uniprot.org/uniprotkb/B7Z0R3" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B7Z0R3", "url": "https://www.uniprot.org/uniprotkb/B7Z0R3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7Z0R3-1", "start_pos": "54", "end_pos": "54", "site_lbl": "Thr54", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B7Z0M7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0M7", "url": "https://www.uniprot.org/uniprotkb/B7Z0M7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1224, "chemical_mass": 133145.0, "gene_names": "Sordl;CG4836;DM_7300579;Dmel\\CG4836;Dmel_CG4836;SODH-1;Srd;anon-WO0140519.105;anon-WO0140519.33;bs15h04.y1;bs36e10.y1", "protein_name": "Alcohol dehydrogenase-like N-terminal domain-containing protein", "disease": [], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B7Z0M7", "url": "https://www.uniprot.org/uniprotkb/B7Z0M7" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "B7Z0M7", "url": "https://www.uniprot.org/uniprotkb/B7Z0M7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B7Z0M7", "url": "https://www.uniprot.org/uniprotkb/B7Z0M7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0C4FEI3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0C4FEI3", "url": "https://www.uniprot.org/uniprotkb/A0A0C4FEI3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1029, "chemical_mass": 113020.0, "gene_names": "Dmel\\CG6184;CG6184;Dmel\\CG6184;Dmel_CG6184", "protein_name": "FAM234A/B beta-propeller domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4FEI3", "url": "https://www.uniprot.org/uniprotkb/A0A0C4FEI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0C4FEI3-1", "start_pos": "818", "end_pos": "818", "site_lbl": "Thr818", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 818, "start_aa": "Thr", "end_pos": 818, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr818", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8DZ15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DZ15", "url": "https://www.uniprot.org/uniprotkb/A8DZ15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 292, "chemical_mass": 33020.0, "gene_names": "Dmel\\CG34171;CG34171;Dmel\\CG34171;Dmel_CG34171;SPH244", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A8DZ15", "url": "https://www.uniprot.org/uniprotkb/A8DZ15" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A8DZ15", "url": "https://www.uniprot.org/uniprotkb/A8DZ15" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A8DZ15", "url": "https://www.uniprot.org/uniprotkb/A8DZ15" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A8DZ15", "url": "https://www.uniprot.org/uniprotkb/A8DZ15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "M9MSK1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MSK1", "url": "https://www.uniprot.org/uniprotkb/M9MSK1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 356, "chemical_mass": 39027.0, "gene_names": "Dmel\\CG32846;CG32846;Dmel\\CG32846;Dmel_CG32846", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9MSK1-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Thr337", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 337, "start_aa": "Thr", "end_pos": 337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B7YZP6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1102, "chemical_mass": 121629.0, "gene_names": "sona;CG11169;CG9850;Dimp;Dmel\\CG9850;Dmel_CG9850;Sona;dimp;sona", "protein_name": "", "disease": [ { "disease_id": "DOID:0050784", "name": "primary progressive multiple sclerosis", "description": "A multiple sclerosis that is characterized by steady worsening of neurologic functioning, without any distinct relapses or periods of remission. The rate of progression may vary over time, with occasional plateaus or temporary improvements, but the progression is continuous.", "url": "https://disease-ontology.org/term/DOID:0050784", "evidence": [ { "id": "0050784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050784" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11383", "name": "cryptorchidism", "description": "", "url": "https://disease-ontology.org/term/DOID:11383", "evidence": [ { "id": "11383", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11383" } ], "weight": 0.0 }, { "disease_id": "DOID:12336", "name": "male infertility", "description": "", "url": "https://disease-ontology.org/term/DOID:12336", "evidence": [ { "id": "12336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12336" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2378", "name": "relapsing-remitting multiple sclerosis", "description": "A multiple sclerosis that is characterized by relapse (attacks of symptom flare-ups) followed by remission (periods of recovery). Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles.", "url": "https://disease-ontology.org/term/DOID:2378", "evidence": [ { "id": "2378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2378" } ], "weight": 0.0 }, { "disease_id": "DOID:5199", "name": "ureteral obstruction", "description": "An urinary tract obstruction that is characterized by a blockage in one or both of the tubes (ureters) that carry urine from the kidneys to the bladder.", "url": "https://disease-ontology.org/term/DOID:5199", "evidence": [ { "id": "5199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5199" } ], "weight": 0.0 }, { "disease_id": "DOID:5200", "name": "urinary tract obstruction", "description": "", "url": "https://disease-ontology.org/term/DOID:5200", "evidence": [ { "id": "5200", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5200" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" }, { "name": "membrane protein ectodomain proteolysis", "id": "GO:0006509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006509", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" }, { "name": "positive regulation of Wnt protein secretion", "id": "GO:0061357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061357", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" }, { "name": "imaginal disc-derived appendage development", "id": "GO:0048737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048737", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" }, { "name": "Golgi-associated vesicle", "id": "GO:0005798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005798", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "B7YZP6", "url": "https://www.uniprot.org/uniprotkb/B7YZP6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7YZP6-1", "start_pos": "927", "end_pos": "927", "site_lbl": "Thr927", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 927, "start_aa": "Thr", "end_pos": 927, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr927", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "B7YZP6-1", "start_pos": "938", "end_pos": "938", "site_lbl": "Thr938", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 938, "start_aa": "Thr", "end_pos": 938, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr938", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KH14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH14", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 164, "chemical_mass": 18234.0, "gene_names": "Dmel\\CG5447;CG5447;Dmel\\CG5447;Dmel_CG5447", "protein_name": "Ras modification protein ERF4", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH14", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH14" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH14", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH14" } ], "pmid": "" }, { "name": "palmitoyltransferase complex", "id": "GO:0002178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002178", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH14", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH14" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH14", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH14" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH14", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KH14-1", "start_pos": "8", "end_pos": "8", "site_lbl": "Thr8", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 8, "start_aa": "Thr", "end_pos": 8, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr8", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KH71-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KH71", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KH71" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 60, "chemical_mass": 6190.0, "gene_names": "Dmel\\CG44040;CG44040;Dmel\\CG44040;Dmel_CG44040", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KHA8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHA8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHA8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1597, "chemical_mass": 178035.0, "gene_names": "Dmel\\CG14322;CG14322;Dmel\\CG14322;Dmel_CG14322", "protein_name": "Zinc finger protein 106", "disease": [ { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHA8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHA8" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHA8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHA8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHA8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHA8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHA8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHA8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KHC1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHC1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 93, "chemical_mass": 11007.0, "gene_names": "Dmel\\CG44158;CG44158;Dmel\\CG44158;Dmel_CG44158", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A126GUT7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A126GUT7", "url": "https://www.uniprot.org/uniprotkb/A0A126GUT7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 671, "chemical_mass": 76796.0, "gene_names": "Dmel\\CG12402;CG12402;Dmel\\CG12402;Dmel_CG12402;FBXL11", "protein_name": "F-box domain-containing protein", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUT7", "url": "https://www.uniprot.org/uniprotkb/A0A126GUT7" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUT7", "url": "https://www.uniprot.org/uniprotkb/A0A126GUT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A126GUT7-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A126GUT7-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Thr57", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KHX7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1591, "chemical_mass": 178868.0, "gene_names": "Gcn2;CG1609;DGCN2;Dmel\\CG1609;Dmel_CG1609;GCN-2;GCN2;Gcn-2;Gcn2;dGCN2;dGcn2;gcn2", "protein_name": "non-specific serine/threonine protein kinase", "disease": [ { "disease_id": "DOID:0081269", "name": "pulmonary venoocclusive disease 2", "description": "A pulmonary venoocclusive disease that has_material_basis_in homozygous or compound heterozygous mutation in the EIF2AK4 gene on chromosome 15q15 and that is characterized histologically by widespread fibrous intimal proliferation of septal veins and preseptal venules, and is frequently associated with pulmonary capillary dilatation and proliferation.", "url": "https://disease-ontology.org/term/DOID:0081269", "evidence": [ { "id": "0081269", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081269" } ], "weight": 0.0 }, { "disease_id": "DOID:5453", "name": "pulmonary venoocclusive disease", "description": "A pulmonary hypertension that is characterized by pulmonary venous constriction or occlusion, resulting in pulmonary hypertension.", "url": "https://disease-ontology.org/term/DOID:5453", "evidence": [ { "id": "5453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5453" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "eukaryotic translation initiation factor 2alpha kinase activity", "id": "GO:0004694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004694", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of metabolic process", "id": "GO:0009893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009893", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "positive regulation of cell size", "id": "GO:0045793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045793", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "negative regulation of translational initiation in response to stress", "id": "GO:0032057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032057", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHX7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KHY1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHY1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHY1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 328, "chemical_mass": 37713.0, "gene_names": "anon-WO0118547.412;CG2126;Dmel\\CG2126;Dmel_CG2126;anon-WO0118547.412", "protein_name": "JNK1/MAPK8-associated membrane protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHY1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHY1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHY1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHY1" } ], "pmid": "" } ], "biological_process": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHY1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHY1" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHY1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHY1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KI44-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI44", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI44" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1433, "chemical_mass": 157858.0, "gene_names": "Tusp;CG5586;DMG2-MB6.chr3R.24.043;Dmel\\CG5586;Dmel_CG5586;TUSP;Tusp", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI44", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI44" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI44", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI44" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI44", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI44" } ], "pmid": "" }, { "name": "SNARE complex assembly", "id": "GO:0035493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035493", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI44", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI44" } ], "pmid": "" }, { "name": "synaptic signaling", "id": "GO:0099536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099536", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI44", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI44" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KI44-1", "start_pos": "930", "end_pos": "930", "site_lbl": "Thr930", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 930, "start_aa": "Thr", "end_pos": 930, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr930", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4KI44-1", "start_pos": "968", "end_pos": "968", "site_lbl": "Thr968", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 968, "start_aa": "Thr", "end_pos": 968, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr968", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4KI01-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI01", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI01" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 218, "chemical_mass": 24582.0, "gene_names": "CG1540;Dmel\\CG31051;CG1540;CG31051;CT3186;Dmel\\CG31051;Dmel_CG31051", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LEE2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LEE2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LEE2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 174, "chemical_mass": 20762.0, "gene_names": "Dmel\\CG12836;CG12836;Dmel\\CG12836;Dmel_CG12836;mdcds_19139", "protein_name": "Tctex1 domain-containing protein 2", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LEE2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LEE2" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LEE2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LEE2" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LEE2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LEE2" } ], "pmid": "" } ], "molecular_function": [ { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LEE2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LEE2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7K4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7K4", "url": "https://www.uniprot.org/uniprotkb/A1Z7K4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 227, "chemical_mass": 25273.0, "gene_names": "Dmel\\CG8248;CG8248;Dmel\\CG8248;Dmel_CG8248", "protein_name": "Transmembrane protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LET0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LET0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LET0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 543, "chemical_mass": 61945.0, "gene_names": "Dmel\\CG7737;CG7737;Dmel\\CG7737;Dmel_CG7737;PAOX", "protein_name": "Amine oxidase domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LET0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LET0" } ], "pmid": "" } ], "molecular_function": [ { "name": "polyamine oxidase activity", "id": "GO:0046592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046592", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LET0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LET0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7S3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 686, "chemical_mass": 74701.0, "gene_names": "Rab32;24652026;24652028;A1Z7S1;CG8024;DRABR1;DmRab32;Dmel\\CG8024;Dmel_CG8024;DrabRP1;Ltd;RAB-RP1;RAB7L;RP1;Rab-RP1/CG8024;Rab-RP1;Rab-r1;Rab32/RP1;Rab32;Rab7L1;RabRP1;anon-WO0118547.106;beck;ltd;rab32", "protein_name": "", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:3753", "name": "Hermansky-Pudlak syndrome", "description": "A syndrome characterized by oculocutaneous albinism, bleeding problems due to platelet storage pool defect, visual impairment and lysosomal accumulation of ceroid lipofuscin.", "url": "https://disease-ontology.org/term/DOID:3753", "evidence": [ { "id": "3753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3753" } ], "weight": 0.0 }, { "disease_id": "DOID:576", "name": "proteinuria", "description": "A kidney disease that is characterized by the presence of excess proteins in the urine.", "url": "https://disease-ontology.org/term/DOID:576", "evidence": [ { "id": "576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:576" } ], "weight": 0.0 } ], "biological_process": [ { "name": "eye pigment granule organization", "id": "GO:0008057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008057", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "regulation of lipid storage", "id": "GO:0010883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010883", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "compound eye pigmentation", "id": "GO:0048072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048072", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "mitochondrial transport", "id": "GO:0006839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006839", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "melanosome organization", "id": "GO:0032438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032438", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "ommochrome biosynthetic process", "id": "GO:0006727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006727", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A1Z7S3", "url": "https://www.uniprot.org/uniprotkb/A1Z7S3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z7S3-1", "start_pos": "211", "end_pos": "211", "site_lbl": "Thr211", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 211, "start_aa": "Thr", "end_pos": 211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr211", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A1Z7S3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A1Z7S3" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LF36-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF36", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF36" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 76, "chemical_mass": 8357.0, "gene_names": "COX7CL;CG44296;COX7CL;Dmel\\CG44296;Dmel_CG44296", "protein_name": "Cytochrome c oxidase subunit 7C, mitochondrial", "disease": [ { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF36", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF36" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF36", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF36" } ], "pmid": "" }, { "name": "respiratory chain complex IV", "id": "GO:0045277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045277", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF36", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF36" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial electron transport, cytochrome c to oxygen", "id": "GO:0006123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006123", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF36", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF36" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LF84-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LF84", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LF84" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 214, "chemical_mass": 25533.0, "gene_names": "Dmel\\CG44341;CG44341;Dmel\\CG44341;Dmel_CG44341", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LFF6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LFF6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LFF6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 594, "chemical_mass": 62822.0, "gene_names": "Dmel\\CG8180;CG8180;Dmel\\CG8180;Dmel_CG8180", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4LFF6-1", "start_pos": "578", "end_pos": "578", "site_lbl": "Thr578", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 578, "start_aa": "Thr", "end_pos": 578, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr578", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZA45-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA45", "url": "https://www.uniprot.org/uniprotkb/A1ZA45" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1263, "chemical_mass": 132388.0, "gene_names": "CG12966;CG12967;CG12305;CG12966;CG12967;CG30089;Dmel\\CG30089;Dmel_CG30089", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZA45-1", "start_pos": "1142", "end_pos": "1142", "site_lbl": "Thr1142", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1142, "start_aa": "Thr", "end_pos": 1142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1142", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LFN2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LFN2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LFN2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 27, "chemical_mass": 3256.0, "gene_names": "Dmel\\CG45087;CG45087;Dmel\\CG45087;Dmel_CG45087;Dromel_CG17725_FBtr0086701_pepck_uORF", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "B7YZK8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1517, "chemical_mass": 164252.0, "gene_names": "tn;Abba;CG15105;Dmel\\CG15105;Dmel_CG15105;TRIM32;Thin;Tn;abba;l(2)tn;tn", "protein_name": "", "disease": [ { "disease_id": "DOID:0110161", "name": "Charcot-Marie-Tooth disease type 2R", "description": "A Charcot-Marie-Tooth disease type 2 that has_material_basis_in homozygous or compound heterozygous mutation in the TRIM2 gene on chromosome 4q.", "url": "https://disease-ontology.org/term/DOID:0110161", "evidence": [ { "id": "0110161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110161" } ], "weight": 0.0 }, { "disease_id": "DOID:0110274", "name": "autosomal recessive limb-girdle muscular dystrophy", "description": "A limb-girdle muscular dystrophy has_material_basis_in autosomal recessive inheritance.", "url": "https://disease-ontology.org/term/DOID:0110274", "evidence": [ { "id": "0110274", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110274" } ], "weight": 0.0 }, { "disease_id": "DOID:0110282", "name": "autosomal recessive limb-girdle muscular dystrophy type 2H", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in mutation in the gene encoding tripartite motif-containing protein-32 (TRIM32) on chromosome 9q.", "url": "https://disease-ontology.org/term/DOID:0110282", "evidence": [ { "id": "0110282", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110282" } ], "weight": 0.0 }, { "disease_id": "DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration.", "url": "https://disease-ontology.org/term/DOID:9884", "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" } ], "biological_process": [ { "name": "muscle cell cellular homeostasis", "id": "GO:0046716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046716", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "striated muscle contraction", "id": "GO:0006941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006941", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "muscle cell development", "id": "GO:0055001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055001", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "myofibril assembly", "id": "GO:0030239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030239", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "positive regulation of glycolytic process", "id": "GO:0045821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045821", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "larval locomotory behavior", "id": "GO:0008345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008345", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" }, { "name": "positive regulation of amino acid biosynthetic process", "id": "GO:2000284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000284", "evidence": [ { "database": "UniProtKB", "id": "B7YZK8", "url": "https://www.uniprot.org/uniprotkb/B7YZK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "B7YZK8-1", "start_pos": "925", "end_pos": "925", "site_lbl": "Thr925", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 925, "start_aa": "Thr", "end_pos": 925, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr925", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LFY6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LFY6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LFY6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 375, "chemical_mass": 43048.0, "gene_names": "CG15672;Dmel\\CG30222;CG12709;CG15672;CG30222;Dmel\\CG30222;Dmel_CG30222", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LG18-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LG18" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 740, "chemical_mass": 83339.0, "gene_names": "Dmel\\CG9313;CG9313;Dmel\\CG9313;Dmel_CG9313", "protein_name": "Dynein intermediate chain 2, ciliary", "disease": [ { "disease_id": "DOID:0050144", "name": "Kartagener syndrome", "description": "A primary ciliary dyskinesia that is characterized by sinusitis, bronchiectasis and situs inversus with dextrocardia resulting from dysfunction of the cilia during embryologic development.", "url": "https://disease-ontology.org/term/DOID:0050144", "evidence": [ { "id": "0050144", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050144" } ], "weight": 0.0 }, { "disease_id": "DOID:0050545", "name": "visceral heterotaxy", "description": "A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.", "url": "https://disease-ontology.org/term/DOID:0050545", "evidence": [ { "id": "0050545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050545" } ], "weight": 0.0 }, { "disease_id": "DOID:0110594", "name": "primary ciliary dyskinesia 1", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with outer dynein arm defect and in about half of patients situs inversus and has_material_basis_in compound heterozygous mutation in the DNAI1 gene on chromosome 9p13.", "url": "https://disease-ontology.org/term/DOID:0110594", "evidence": [ { "id": "0110594", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110594" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LG18" } ], "pmid": "" }, { "name": "outer dynein arm", "id": "GO:0036157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036157", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LG18" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LG18" } ], "pmid": "" }, { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LG18" } ], "pmid": "" }, { "name": "outer dynein arm assembly", "id": "GO:0036158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036158", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LG18" } ], "pmid": "" } ], "molecular_function": [ { "name": "dynein light chain binding", "id": "GO:0045503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045503", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LG18" } ], "pmid": "" }, { "name": "dynein heavy chain binding", "id": "GO:0045504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045504", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LG18", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LG18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LGG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1423, "chemical_mass": 155860.0, "gene_names": "Dmel\\CG3328;CG3328;Dmel\\CG3328;Dmel_CG3328", "protein_name": "Myelin regulatory factor", "disease": [ { "disease_id": "DOID:0080634", "name": "nanophthalmos", "description": "A microphthalmia that is characterized by a small eye with a short axial length, severe hyperopia, an elevated lens/eye ratio, and a high incidence of angle-closure glaucoma.", "url": "https://disease-ontology.org/term/DOID:0080634", "evidence": [ { "id": "0080634", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080634" } ], "weight": 0.0 }, { "disease_id": "DOID:1405", "name": "primary angle-closure glaucoma", "description": "An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.", "url": "https://disease-ontology.org/term/DOID:1405", "evidence": [ { "id": "1405", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1405" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:3827", "name": "congenital diaphragmatic hernia", "description": "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs.", "url": "https://disease-ontology.org/term/DOID:3827", "evidence": [ { "id": "3827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3827" } ], "weight": 0.0 }, { "disease_id": "DOID:5614", "name": "eye disease", "description": "An eye and adnexa disease that is located_in the eye.", "url": "https://disease-ontology.org/term/DOID:5614", "evidence": [ { "id": "5614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5614" } ], "weight": 0.0 }, { "disease_id": "DOID:9834", "name": "hyperopia", "description": "A refractive error that is characterized by rays of light entering the eye parallel to the optic axis are brought to a focus behind the retina, as a result of the eyeball being too short from front to back.", "url": "https://disease-ontology.org/term/DOID:9834", "evidence": [ { "id": "9834", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9834" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" }, { "name": "protein autoprocessing", "id": "GO:0016540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016540", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGG8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4LGG8-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Thr312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 312, "start_aa": "Thr", "end_pos": 312, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr312", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LGH8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGH8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 457, "chemical_mass": 52404.0, "gene_names": "Dmel\\CG3860;CG3860;Dmel\\CG3860;Dmel_CG3860", "protein_name": "Oxysterol-binding protein", "disease": [ { "disease_id": "DOID:0050545", "name": "visceral heterotaxy", "description": "A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.", "url": "https://disease-ontology.org/term/DOID:0050545", "evidence": [ { "id": "0050545", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050545" } ], "weight": 0.0 }, { "disease_id": "DOID:0110588", "name": "autosomal dominant nonsyndromic deafness 67", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in mutation in the OSBPL2 gene on chromosome 20q13.", "url": "https://disease-ontology.org/term/DOID:0110588", "evidence": [ { "id": "0110588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110588" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGH8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGH8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGH8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGH8" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGH8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGH8" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGH8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGH8" } ], "pmid": "" } ], "molecular_function": [ { "name": "sterol binding", "id": "GO:0032934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032934", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGH8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGH8" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGH8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGH8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LGP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGP2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 38, "chemical_mass": 4377.0, "gene_names": "Hdac3-5'utr;CG45100;Dmel\\CG45100;Dmel_CG45100;Dmel_Hdac3_uORF;Hdac3-5'utr", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LGW0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LGW0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LGW0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 58, "chemical_mass": 6511.0, "gene_names": "Dmel\\CG45545;CG45545;Dmel\\CG45545;Dmel_CG45545;FBgn0267105", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZB14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB14", "url": "https://www.uniprot.org/uniprotkb/A1ZB14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1284, "chemical_mass": 141378.0, "gene_names": "Elk;CG5076;Dmel\\CG5076;Dmel_CG5076;Elk;dmELK;elk", "protein_name": "", "disease": [ { "disease_id": "DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina.", "url": "https://disease-ontology.org/term/DOID:8466", "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ], "weight": 0.0 } ], "biological_process": [ { "name": "potassium ion transport", "id": "GO:0006813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006813", "evidence": [ { "database": "UniProtKB", "id": "A1ZB14", "url": "https://www.uniprot.org/uniprotkb/A1ZB14" } ], "pmid": "" }, { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "A1ZB14", "url": "https://www.uniprot.org/uniprotkb/A1ZB14" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A1ZB14", "url": "https://www.uniprot.org/uniprotkb/A1ZB14" } ], "pmid": "" } ], "cellular_component": [ { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A1ZB14", "url": "https://www.uniprot.org/uniprotkb/A1ZB14" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1ZB14", "url": "https://www.uniprot.org/uniprotkb/A1ZB14" } ], "pmid": "" } ], "molecular_function": [ { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A1ZB14", "url": "https://www.uniprot.org/uniprotkb/A1ZB14" } ], "pmid": "" }, { "name": "voltage-gated monoatomic cation channel activity", "id": "GO:0022843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022843", "evidence": [ { "database": "UniProtKB", "id": "A1ZB14", "url": "https://www.uniprot.org/uniprotkb/A1ZB14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZB14-1", "start_pos": "1059", "end_pos": "1059", "site_lbl": "Thr1059", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1059, "start_aa": "Thr", "end_pos": 1059, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1059", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1ZB14-1", "start_pos": "1112", "end_pos": "1112", "site_lbl": "Thr1112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1112, "start_aa": "Thr", "end_pos": 1112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1112", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LHA8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHA8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHA8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 539, "chemical_mass": 60908.0, "gene_names": "BcDNA:AT11052;CG9803;BcDNA:AT11052;CG30416;CG9803;Dmel\\CG30416;Dmel_CG30416", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LHG3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHG3", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHG3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 84, "chemical_mass": 9141.0, "gene_names": "Dmel\\CG45218;CG45218;Dmel\\CG45218;Dmel_CG45218;FBgn0266745", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LHJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 89, "chemical_mass": 9839.0, "gene_names": "Dmel\\CG45079;CG45079;Dmel\\CG45079;Dmel_CG45079", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LHM7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 789, "chemical_mass": 85787.0, "gene_names": "Cad96Cb;CG10421;CG13664;CT29262;Cad96Cb;Cad96C;DCad96Cb;Dmel\\CG13664;Dmel_CG13664;cad96Cb;cad96C;cg13664", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHM7", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LHY0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 186, "chemical_mass": 21032.0, "gene_names": "ymp;BcDNA:AT03213;CG12250;Dmel\\CG12250;Dmel_CG12250;ymp", "protein_name": "", "disease": [], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY0" } ], "pmid": "" } ], "cellular_component": [ { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY0" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY0", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LHR4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1224, "chemical_mass": 138463.0, "gene_names": "GABA-B-R2;:GABA-B-R2;BcDNA:GH07312;CG6706;D-GABA-B-R2;D-GABA[[B]]R2;D-Gaba2;Dmel\\CG6706;Dmel_CG6706;GABA B R2;GABA-B-R2;GABA-BR2;GABA-[[B]]R2;GABA2;GABAB(R2);GABAB-R2;GABABR-R2;GABABR2;GABA[[B]]-R2;GABA[[B]]R2;GB2;GBR;GH07312;anon-WO0170980.58;anon-WO0170980.59;dGB2", "protein_name": "Gamma-aminobutyric acid type B receptor subunit 2", "disease": [ { "disease_id": "DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine.", "url": "https://disease-ontology.org/term/DOID:0050742", "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ], "weight": 0.0 }, { "disease_id": "DOID:0080291", "name": "developmental and epileptic encephalopathy 59", "description": "A developmental and epileptic encephalopathy characterized by severe global developmental delay and onset of seizures in the first months of life that has_material_basis_in heterozygous mutation in the GABBR2 gene on chromosome 9q22.", "url": "https://disease-ontology.org/term/DOID:0080291", "evidence": [ { "id": "0080291", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080291" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "biological_process": [ { "name": "olfactory behavior", "id": "GO:0042048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042048", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "id": "GO:0007193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007193", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "negative regulation of insulin secretion", "id": "GO:0046676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046676", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "cellular response to mechanical stimulus", "id": "GO:0071260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "negative regulation of synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031631", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "G protein-coupled receptor heterodimeric complex", "id": "GO:0038039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038039", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" }, { "name": "G protein-coupled GABA receptor activity", "id": "GO:0004965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004965", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHR4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHR4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B4LIB4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIB4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 65, "chemical_mass": 7729.0, "gene_names": "Dmel\\CG44259;CG44259;Dmel\\CG44259;Dmel_CG44259;FBgn0265199", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0B7P7M6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P7M6", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P7M6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 890, "chemical_mass": 104907.0, "gene_names": "l(2)41Ab;1(2R)B;41Ab;CG40214;CG40334;CG41265;Dmel\\CG41265;Dmel_CG41265;GroupI;l(2)41Ab;l(2)EMS45-10;l(2R)B", "protein_name": "", "disease": [ { "disease_id": "DOID:0110623", "name": "primary ciliary dyskinesia 15", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with inner dynein arm defect, axonemal disorganization, recurrent respiratory infections and has_material_basis_in homozygous or compound heterozygous mutation in the CCDC40 gene on chromosome 17q25.", "url": "https://disease-ontology.org/term/DOID:0110623", "evidence": [ { "id": "0110623", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110623" } ], "weight": 0.0 }, { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P7M6", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P7M6" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P7M6", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P7M6" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P7M6", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P7M6" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P7M6", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P7M6" } ], "pmid": "" }, { "name": "inner dynein arm assembly", "id": "GO:0036159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036159", "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P7M6", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P7M6" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P7M6", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P7M6" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0A0B7P7M6", "url": "https://www.uniprot.org/uniprotkb/A0A0B7P7M6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0C4DH96-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DH96", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DH96" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1174, "chemical_mass": 126147.0, "gene_names": "side-V;34371;CG13546;CG13547;CG13548;CG30188;CG34371;CT32921;CT32922;Dmel\\CG34371;Dmel_CG34371;side-V", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DH96", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DH96" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0C4DH96-1", "start_pos": "989", "end_pos": "989", "site_lbl": "Thr989", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 989, "start_aa": "Thr", "end_pos": 989, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr989", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0C4DH96", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0C4DH96" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A8JQT5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4273, "chemical_mass": 473474.0, "gene_names": "Cdep;BcDNA:AT26639;BcDNA:RH50880;CDEP;CG1283;CG2008;CG31536;CG34306;CG44193;Cdep;Dmel\\CG44193;Dmel_CG44193;cdep;i23", "protein_name": "Moesin/ezrin/radixin homolog 1", "disease": [ { "disease_id": "DOID:0111790", "name": "congenital nystagmus 1", "description": "A congenital nystagmus that has_material_basis_in mutation in the FRMD7 gene (FERM domain-containing-7) on chromosome Xq26.", "url": "https://disease-ontology.org/term/DOID:0111790", "evidence": [ { "id": "0111790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111790" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "rhabdomere", "id": "GO:0016028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016028", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" } ], "biological_process": [ { "name": "Rac protein signal transduction", "id": "GO:0016601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016601", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" }, { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A8JQT5", "url": "https://www.uniprot.org/uniprotkb/A8JQT5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JQT5-1", "start_pos": "2792", "end_pos": "2792", "site_lbl": "Thr2792", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2792, "start_aa": "Thr", "end_pos": 2792, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2792", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8JQT5-1", "start_pos": "3810", "end_pos": "3810", "site_lbl": "Thr3810", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3810, "start_aa": "Thr", "end_pos": 3810, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3810", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8JQT5-1", "start_pos": "57", "end_pos": "57", "site_lbl": "Thr57", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A0C4DHA5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHA5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHA5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 49581.0, "gene_names": "Dmel\\CG1116;Rgp1;CG1116;Dmel\\CG1116;Dmel_CG1116;Rgp1;anon-WO0118547.337;cg1116", "protein_name": "RAB6A-GEF complex partner protein 2", "disease": [], "cellular_component": [ { "name": "Ric1-Rgp1 guanyl-nucleotide exchange factor complex", "id": "GO:0034066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034066", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHA5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHA5" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHA5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHA5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHA5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHA5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHA5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHA5" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHA5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHA5" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A0C4DHA5", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DHA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A126GUR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A126GUR2", "url": "https://www.uniprot.org/uniprotkb/A0A126GUR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 666, "chemical_mass": 67087.0, "gene_names": "mdcds_43655;CG31556;CG46026;Dmel\\CG46026;Dmel_CG46026;mdcds_43655", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A140SRF8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 265, "chemical_mass": 29687.0, "gene_names": "Rer1;CG11857;Dmel\\CG11857;Dmel_CG11857", "protein_name": "Protein RER1", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "pmid": "" }, { "name": "protein retention in ER lumen", "id": "GO:0006621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006621", "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "pmid": "" }, { "name": "cellular response to unfolded protein", "id": "GO:0034620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034620", "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "pmid": "" }, { "name": "cell competition in a multicellular organism", "id": "GO:0035212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035212", "evidence": [ { "database": "UniProtKB", "id": "A0A140SRF8", "url": "https://www.uniprot.org/uniprotkb/A0A140SRF8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A1W5PX42-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A1W5PX42", "url": "https://www.uniprot.org/uniprotkb/A0A1W5PX42" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 57, "chemical_mass": 6529.0, "gene_names": "CR42848;CG46304;CR42848;Dmel\\CG46304;Dmel_CG46304", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A1W5Q0T5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A1W5Q0T5", "url": "https://www.uniprot.org/uniprotkb/A0A1W5Q0T5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 42, "chemical_mass": 4978.0, "gene_names": "Dmel\\CG46309;CG46309;Dmel\\CG46309;Dmel_CG46309;PRL-1-5'utr", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A1Z1CH18-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CH18", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CH18" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 571, "chemical_mass": 64038.0, "gene_names": "Dmel\\CG11498;CG11498;Dmel\\CG11498;Dmel_CG11498", "protein_name": "Mitochondria-eating protein", "disease": [], "cellular_component": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CH18", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CH18" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CH18", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CH18" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CH18", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CH18" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial protein catabolic process", "id": "GO:0035694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035694", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CH18", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CH18" } ], "pmid": "" }, { "name": "mitophagy by internal vacuole formation", "id": "GO:0035695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035695", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CH18", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CH18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A1Z1CK50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK50", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 194, "chemical_mass": 22688.0, "gene_names": "Dmel\\CG34308;CG34308;Dmel\\CG34308;Dmel_CG34308", "protein_name": "RING-type E3 ubiquitin transferase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK50", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK50" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK50", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK50" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK50", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK50" } ], "pmid": "" }, { "name": "ubiquitin-like protein conjugating enzyme binding", "id": "GO:0044390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044390", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK50", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK50" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK50", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK50" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK50", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK50" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CK50", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CK50" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A1Z1CK50-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Thr189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A1Z1CLY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A1Z1CLY5", "url": "https://www.uniprot.org/uniprotkb/A0A1Z1CLY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 30, "chemical_mass": 3867.0, "gene_names": "CG13004-5'utr;CG13004-5'utr;CG46306;Dmel\\CG46306;Dmel_CG46306", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A2U8U1P3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A2U8U1P3", "url": "https://www.uniprot.org/uniprotkb/A0A2U8U1P3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 433, "chemical_mass": 50576.0, "gene_names": "Cyp9f3;9f3p;CG17875;CR17875;Cyp9f3Psi;Cyp9f3p;Cyp9f3;Dmel\\CG17875;Dmel_CG17875", "protein_name": "", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0060903", "name": "thrombosis", "description": "A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.", "url": "https://disease-ontology.org/term/DOID:0060903", "evidence": [ { "id": "0060903", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060903" } ], "weight": 0.0 }, { "disease_id": "DOID:0070658", "name": "alcohol-associated liver disease", "description": "A liver disease resulting from excessive alcohol intake.", "url": "https://disease-ontology.org/term/DOID:0070658", "evidence": [ { "id": "0070658", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070658" } ], "weight": 0.0 }, { "disease_id": "DOID:0080630", "name": "B-lymphoblastic leukemia/lymphoma", "description": "A B-cell acute lymphoblastic leukemia that is characterized by the presence of too many B-cell lymphoblasts in the blood and bone marrow.", "url": "https://disease-ontology.org/term/DOID:0080630", "evidence": [ { "id": "0080630", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080630" } ], "weight": 0.0 }, { "disease_id": "DOID:0080998", "name": "acute necrotizing pancreatitis", "description": "An acute pancreatitis that is characterized by one or more areas of necrosis in the pancreas with varying degree of involvement of the surrounding tissues or organ systems.", "url": "https://disease-ontology.org/term/DOID:0080998", "evidence": [ { "id": "0080998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080998" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10825", "name": "essential hypertension", "description": "A hypertension with no known cause. It is the most common type of hypertension.", "url": "https://disease-ontology.org/term/DOID:10825", "evidence": [ { "id": "10825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10825" } ], "weight": 0.0 }, { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:11111", "name": "hydronephrosis", "description": "An urinary system disease that is characterized by swelling of one or both kidneys due to incomplete voiding of urine.", "url": "https://disease-ontology.org/term/DOID:11111", "evidence": [ { "id": "11111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11111" } ], "weight": 0.0 }, { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:5773", "name": "oral submucous fibrosis", "description": "A mouth disease that is characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues.", "url": "https://disease-ontology.org/term/DOID:5773", "evidence": [ { "id": "5773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5773" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9477", "name": "pulmonary embolism", "description": "An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot.", "url": "https://disease-ontology.org/term/DOID:9477", "evidence": [ { "id": "9477", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9477" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A2U8U1P3", "url": "https://www.uniprot.org/uniprotkb/A0A2U8U1P3" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A2U8U1P3", "url": "https://www.uniprot.org/uniprotkb/A0A2U8U1P3" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A2U8U1P3", "url": "https://www.uniprot.org/uniprotkb/A0A2U8U1P3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A384ZD34-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 341, "chemical_mass": 38787.0, "gene_names": "mIF3;CG13163;Dmel\\CG13163;Dmel_CG13163;mIF3", "protein_name": "", "disease": [ { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 } ], "biological_process": [ { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "pmid": "" }, { "name": "mitochondrial translational initiation", "id": "GO:0070124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070124", "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "pmid": "" }, { "name": "translation factor activity, RNA binding", "id": "GO:0008135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008135", "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A384ZD34", "url": "https://www.uniprot.org/uniprotkb/A0A384ZD34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A4D6K3L8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K3L8", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K3L8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 530, "chemical_mass": 59687.0, "gene_names": "Dmel\\CG9706;CG9706;Dmel_CG9706", "protein_name": "Acetyl-coenzyme A transporter 1", "disease": [ { "disease_id": "DOID:0110794", "name": "hereditary spastic paraplegia 42", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the SLC33A1 gene on chromosome 3q25.31.", "url": "https://disease-ontology.org/term/DOID:0110794", "evidence": [ { "id": "0110794", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110794" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K3L8", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K3L8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K3L8", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K3L8" } ], "pmid": "" } ], "molecular_function": [ { "name": "acetyl-CoA transmembrane transporter activity", "id": "GO:0008521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008521", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K3L8", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K3L8" } ], "pmid": "" } ], "biological_process": [ { "name": "acetyl-CoA transmembrane transport", "id": "GO:0035348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035348", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K3L8", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K3L8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A4D6K4B0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4B0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4B0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 65, "chemical_mass": 7538.0, "gene_names": "Dmel\\CG46383;CG46383;Dmel_CG46383", "protein_name": "RING-type domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4B0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4B0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4B0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4B0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K4B0", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K4B0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A4D6K823-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 439, "chemical_mass": 49161.0, "gene_names": "nmo;CG7892;Dmel\\CG7892;Dmel_CG7892;NEMO/NLK;NEMO;NLK;Nemo;Nlk;Nmo;ORE-6;adk1;adk;anon-EST:Gibbs3;anon-EST:Liang-2.43;anon-WO0118547.332;anon-WO0140519.256;anon-WO0172774.138;clone 2.43;nmo", "protein_name": "Mitogen-activated protein kinase", "disease": [ { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "MAP kinase activity", "id": "GO:0004707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004707", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "regulation of establishment of planar polarity", "id": "GO:0090175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090175", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "wing disc dorsal/ventral pattern formation", "id": "GO:0048190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048190", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "positive regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045887", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "imaginal disc-derived wing vein specification", "id": "GO:0007474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007474", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "ommatidial rotation", "id": "GO:0016318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016318", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" }, { "name": "gravitaxis", "id": "GO:0042332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042332", "evidence": [ { "database": "UniProtKB", "id": "A0A4D6K823", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6F7RXE0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6F7RXE0", "url": "https://www.uniprot.org/uniprotkb/A0A6F7RXE0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 431, "chemical_mass": 49030.0, "gene_names": "Dmel\\CG11670;CG11670;Dmel_CG11670;SP27", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7RXE0", "url": "https://www.uniprot.org/uniprotkb/A0A6F7RXE0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7RXE0", "url": "https://www.uniprot.org/uniprotkb/A0A6F7RXE0" } ], "pmid": "" } ], "biological_process": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7RXE0", "url": "https://www.uniprot.org/uniprotkb/A0A6F7RXE0" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7RXE0", "url": "https://www.uniprot.org/uniprotkb/A0A6F7RXE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6F7S5S7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6F7S5S7", "url": "https://www.uniprot.org/uniprotkb/A0A6F7S5S7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 343, "chemical_mass": 38163.0, "gene_names": "Cp7Fa;A;CG15348;CG15349;CG33962;Cp7Fa;Dmel\\CG33962;Dmel_CG33962", "protein_name": "", "disease": [], "molecular_function": [ { "name": "structural constituent of egg chorion", "id": "GO:0005213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005213", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7S5S7", "url": "https://www.uniprot.org/uniprotkb/A0A6F7S5S7" } ], "pmid": "" } ], "biological_process": [ { "name": "chorion-containing eggshell formation", "id": "GO:0007304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007304", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7S5S7", "url": "https://www.uniprot.org/uniprotkb/A0A6F7S5S7" } ], "pmid": "" } ], "cellular_component": [ { "name": "egg chorion", "id": "GO:0042600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042600", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7S5S7", "url": "https://www.uniprot.org/uniprotkb/A0A6F7S5S7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6H2EDS4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EDS4", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EDS4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 42, "chemical_mass": 4935.0, "gene_names": "lncRNA:CR45045;CG45045;CR45045;Dmel\\CG45045;Dmel_CG45045", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6H2EE55-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EE55", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EE55" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1186, "chemical_mass": 129253.0, "gene_names": "Dmel\\CG14431;CG14431;Dmel_CG14431", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EE55", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EE55" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EE55", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EE55" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A6H2EE55-1", "start_pos": "189", "end_pos": "189", "site_lbl": "Thr189", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr189", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EE55-1", "start_pos": "235", "end_pos": "235", "site_lbl": "Thr235", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 235, "start_aa": "Thr", "end_pos": 235, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr235", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EE55-1", "start_pos": "599", "end_pos": "599", "site_lbl": "Thr599", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 599, "start_aa": "Thr", "end_pos": 599, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr599", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EE55-1", "start_pos": "647", "end_pos": "647", "site_lbl": "Thr647", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 647, "start_aa": "Thr", "end_pos": 647, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr647", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6H2EFK9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EFK9", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EFK9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 31, "chemical_mass": 3732.0, "gene_names": "Dmel\\CG46458;CG46458;Dmel_CG46458", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6H2EFZ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EFZ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 117, "chemical_mass": 13930.0, "gene_names": "Dmel\\CG46440;CG46440;Dmel_CG46440", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6H2EJX8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EJX8", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EJX8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 55, "chemical_mass": 6035.0, "gene_names": "Dmel\\CG43610;CG43610;CR43610;Dmel_CG43610;lincRNA.59;lncRNA:CR43610", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6I8WFJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6I8WFJ4", "url": "https://www.uniprot.org/uniprotkb/A0A6I8WFJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 129, "chemical_mass": 14217.0, "gene_names": "Gpa2;CG17878;Dmel\\CG17878;Dmel_CG17878;GPA2;Gpa2;gpa2", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A6I8WFJ4", "url": "https://www.uniprot.org/uniprotkb/A0A6I8WFJ4" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A6I8WFJ4", "url": "https://www.uniprot.org/uniprotkb/A0A6I8WFJ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "hormone receptor binding", "id": "GO:0051427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051427", "evidence": [ { "database": "UniProtKB", "id": "A0A6I8WFJ4", "url": "https://www.uniprot.org/uniprotkb/A0A6I8WFJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6M3Q719-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q719", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q719" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 72, "chemical_mass": 8304.0, "gene_names": "Dmel\\CG46412;CG46412;Dmel_CG46412", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6M3Q7P3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q7P3", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7P3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 60, "chemical_mass": 6788.0, "gene_names": "Dmel\\CG46395;CG46395;Dmel_CG46395", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6M3Q8D7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q8D7", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q8D7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 88, "chemical_mass": 9806.0, "gene_names": "Dmel\\CG45273;CG45273;CR45273;Dmel_CG45273;lncRNA:CR45273", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6M3Q933-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3Q933", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q933" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 34, "chemical_mass": 3734.0, "gene_names": "Dmel\\CG46462;CG46462;Dmel_CG46462", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A0A6M3QGN8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6M3QGN8", "url": "https://www.uniprot.org/uniprotkb/A0A6M3QGN8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 33, "chemical_mass": 3783.0, "gene_names": "Dmel\\CG46435;CG46435;Dmel_CG46435", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z6I7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1460, "chemical_mass": 165061.0, "gene_names": "BubR1;13;31/13;BUB1;BUBR1;BcDNA:LD23835;Bub1;BubR1;CG 7838;CG7838;DmBUB1;DmBubRI;Dmbub1;Dmel\\CG7838;Dmel_CG7838;bub1;bubR1;bubr1;dBUB1;l(2)k03113;l(2)k06109;mcl(2)Z1525", "protein_name": "", "disease": [ { "disease_id": "DOID:0051041", "name": "primary autosomal recessive microcephaly 30", "description": "A primary autosomal recessive microcephaly that is characterized by small head circumference, poor overall growth, and global developmental delay with variably impaired intellectual development and that has_material_basis_in homozygous or compound heterozygous mutation in the BUB1 gene on chromosome 2q13.", "url": "https://disease-ontology.org/term/DOID:0051041", "evidence": [ { "id": "0051041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051041" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "female meiosis sister chromatid cohesion", "id": "GO:0007066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007066", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "meiotic sister chromatid cohesion, centromeric", "id": "GO:0051754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051754", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "regulation of exit from mitosis", "id": "GO:0007096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007096", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "regulation of mitotic sister chromatid separation", "id": "GO:0010965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010965", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "male meiosis sister chromatid cohesion", "id": "GO:0007065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007065", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "synaptonemal complex organization", "id": "GO:0070193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070193", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A1Z6I7", "url": "https://www.uniprot.org/uniprotkb/A1Z6I7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z6I7-1", "start_pos": "610", "end_pos": "610", "site_lbl": "Thr610", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 610, "start_aa": "Thr", "end_pos": 610, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr610", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z6K9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6K9", "url": "https://www.uniprot.org/uniprotkb/A1Z6K9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 504, "chemical_mass": 59002.0, "gene_names": "Dmel\\CG17994;CG17994;Dmel\\CG17994;Dmel_CG17994", "protein_name": "Trichohyalin", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z6L4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6L4", "url": "https://www.uniprot.org/uniprotkb/A1Z6L4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 166, "chemical_mass": 18515.0, "gene_names": "Dmel\\CG15233;BEST:LD11861;CG15233;Dmel\\CG15233;Dmel_CG15233", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z6L8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6L8", "url": "https://www.uniprot.org/uniprotkb/A1Z6L8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 191, "chemical_mass": 22106.0, "gene_names": "Dmel\\CG33919;CG33919;Dmel\\CG33919;Dmel_CG33919", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z6Q3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6Q3", "url": "https://www.uniprot.org/uniprotkb/A1Z6Q3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 656, "chemical_mass": 76926.0, "gene_names": "Dmel\\CG9447;CG9447;Dmel\\CG9447;Dmel_CG9447", "protein_name": "Acyltransferase 3 domain-containing protein", "disease": [], "molecular_function": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "A1Z6Q3", "url": "https://www.uniprot.org/uniprotkb/A1Z6Q3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z6W2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z6W2", "url": "https://www.uniprot.org/uniprotkb/A1Z6W2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 708, "chemical_mass": 81433.0, "gene_names": "Dmel\\CG30384;CG11074;CG30384;Dmel\\CG30384;Dmel_CG30384", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z707-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z707", "url": "https://www.uniprot.org/uniprotkb/A1Z707" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 713, "chemical_mass": 79753.0, "gene_names": "Gpo2;146747_at;CG2137;Dmel\\CG2137;Dmel_CG2137;GPO-2;GPO;Gpo2;Gpo;alpha-GPO;gpo-2", "protein_name": "Glycerol-3-phosphate dehydrogenase", "disease": [ { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "glycerol-3-phosphate dehydrogenase (quinone) activity", "id": "GO:0004368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004368", "evidence": [ { "database": "UniProtKB", "id": "A1Z707", "url": "https://www.uniprot.org/uniprotkb/A1Z707" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A1Z707", "url": "https://www.uniprot.org/uniprotkb/A1Z707" } ], "pmid": "" } ], "biological_process": [ { "name": "glycerol-3-phosphate shuttle", "id": "GO:0006127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006127", "evidence": [ { "database": "UniProtKB", "id": "A1Z707", "url": "https://www.uniprot.org/uniprotkb/A1Z707" } ], "pmid": "" }, { "name": "glycerol-3-phosphate metabolic process", "id": "GO:0006072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006072", "evidence": [ { "database": "UniProtKB", "id": "A1Z707", "url": "https://www.uniprot.org/uniprotkb/A1Z707" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A1Z707", "url": "https://www.uniprot.org/uniprotkb/A1Z707" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z765-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z765", "url": "https://www.uniprot.org/uniprotkb/A1Z765" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 202, "chemical_mass": 21652.0, "gene_names": "Dmel\\CG12159;CG12159;Dmel\\CG12159;Dmel_CG12159", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z765", "url": "https://www.uniprot.org/uniprotkb/A1Z765" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z777-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z777", "url": "https://www.uniprot.org/uniprotkb/A1Z777" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 148, "chemical_mass": 16964.0, "gene_names": "Dmel\\CG30378;CBP6;CG30378;Dmel\\CG30378;Dmel_CG30378;NEST:bs08d04", "protein_name": "EF-hand domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z777", "url": "https://www.uniprot.org/uniprotkb/A1Z777" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A1Z777", "url": "https://www.uniprot.org/uniprotkb/A1Z777" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A1Z777", "url": "https://www.uniprot.org/uniprotkb/A1Z777" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "A1Z777", "url": "https://www.uniprot.org/uniprotkb/A1Z777" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A1Z777", "url": "https://www.uniprot.org/uniprotkb/A1Z777" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7D2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7D2", "url": "https://www.uniprot.org/uniprotkb/A1Z7D2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 399, "chemical_mass": 43616.0, "gene_names": "CG2280;CG2280;CG30371;Dmel\\CG30371;Dmel_CG30371;SP80a;SP80", "protein_name": "", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D2", "url": "https://www.uniprot.org/uniprotkb/A1Z7D2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D2", "url": "https://www.uniprot.org/uniprotkb/A1Z7D2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D2", "url": "https://www.uniprot.org/uniprotkb/A1Z7D2" } ], "pmid": "" }, { "name": "defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D2", "url": "https://www.uniprot.org/uniprotkb/A1Z7D2" } ], "pmid": "" }, { "name": "positive regulation of melanization defense response", "id": "GO:0035008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035008", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D2", "url": "https://www.uniprot.org/uniprotkb/A1Z7D2" } ], "pmid": "" }, { "name": "Toll receptor ligand protein activation cascade", "id": "GO:0160032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160032", "evidence": [ { "database": "UniProtKB", "id": "A1Z7D2", "url": "https://www.uniprot.org/uniprotkb/A1Z7D2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z7D2-1", "start_pos": "294", "end_pos": "294", "site_lbl": "Thr294", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 294, "start_aa": "Thr", "end_pos": 294, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr294", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7K8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7K8", "url": "https://www.uniprot.org/uniprotkb/A1Z7K8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 34401.0, "gene_names": "AIMP1;AIMP1;CG8235;Dmel\\CG8235;Dmel_CG8235", "protein_name": "", "disease": [ { "disease_id": "DOID:0060790", "name": "hypomyelinating leukodystrophy 3", "description": "A hypomyelinating leukodystrophy characterized by autosomal recessive inheritance of early infantile onset of global developmental delay, lack of development, lack of speech acquisition, and peripheral spasticity associated with decreased myelination in the central nervous system that has_material_basis_in homozygous mutation in the AIMP1 gene on chromosome 4q24.", "url": "https://disease-ontology.org/term/DOID:0060790", "evidence": [ { "id": "0060790", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060790" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z7K8", "url": "https://www.uniprot.org/uniprotkb/A1Z7K8" } ], "pmid": "" }, { "name": "aminoacyl-tRNA synthetase multienzyme complex", "id": "GO:0017101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017101", "evidence": [ { "database": "UniProtKB", "id": "A1Z7K8", "url": "https://www.uniprot.org/uniprotkb/A1Z7K8" } ], "pmid": "" } ], "molecular_function": [ { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A1Z7K8", "url": "https://www.uniprot.org/uniprotkb/A1Z7K8" } ], "pmid": "" } ], "biological_process": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A1Z7K8", "url": "https://www.uniprot.org/uniprotkb/A1Z7K8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7L6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7L6", "url": "https://www.uniprot.org/uniprotkb/A1Z7L6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 335, "chemical_mass": 36456.0, "gene_names": "Dmel\\CG8229;Uspl1l;CG8229;Dmel\\CG8229;Dmel_CG8229;Uspl1l", "protein_name": "", "disease": [], "cellular_component": [ { "name": "super elongation complex", "id": "GO:0032783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032783", "evidence": [ { "database": "UniProtKB", "id": "A1Z7L6", "url": "https://www.uniprot.org/uniprotkb/A1Z7L6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z7L6-1", "start_pos": "254", "end_pos": "254", "site_lbl": "Thr254", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 254, "start_aa": "Thr", "end_pos": 254, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr254", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7M0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7M0", "url": "https://www.uniprot.org/uniprotkb/A1Z7M0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 245, "chemical_mass": 26785.0, "gene_names": "spab;CG8216;Dmel\\CG8216;Dmel_CG8216;spab", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7P1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7P1", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 623, "chemical_mass": 69917.0, "gene_names": "Pgm2a;CG8073;Dmel\\CG8073;Dmel_CG8073;Pgm2a;Pmm45A", "protein_name": "", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P1", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ], "pmid": "" }, { "name": "phosphoglucomutase activity", "id": "GO:0004614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004614", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P1", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ], "pmid": "" }, { "name": "phosphopentomutase activity", "id": "GO:0008973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008973", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P1", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P1", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ], "pmid": "" } ], "biological_process": [ { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P1", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ], "pmid": "" }, { "name": "purine ribonucleoside salvage", "id": "GO:0006166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006166", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P1", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7P3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7P3", "url": "https://www.uniprot.org/uniprotkb/A1Z7P3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 453, "chemical_mass": 51126.0, "gene_names": "Phax;BEST:GH22533;CG8069;Dmel\\CG8069;Dmel_CG8069;Phax;dPHAX", "protein_name": "Phosphorylated adapter RNA export protein", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P3", "url": "https://www.uniprot.org/uniprotkb/A1Z7P3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P3", "url": "https://www.uniprot.org/uniprotkb/A1Z7P3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P3", "url": "https://www.uniprot.org/uniprotkb/A1Z7P3" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P3", "url": "https://www.uniprot.org/uniprotkb/A1Z7P3" } ], "pmid": "" }, { "name": "snRNA export from nucleus", "id": "GO:0006408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006408", "evidence": [ { "database": "UniProtKB", "id": "A1Z7P3", "url": "https://www.uniprot.org/uniprotkb/A1Z7P3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z7P3-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z7T9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7T9", "url": "https://www.uniprot.org/uniprotkb/A1Z7T9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 875, "chemical_mass": 94702.0, "gene_names": "BcDNA:GH21254;BcDNA:GH21254;CG13739;Dmel\\CG13739;Dmel_CG13739", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z824-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z824", "url": "https://www.uniprot.org/uniprotkb/A1Z824" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 340, "chemical_mass": 38123.0, "gene_names": "SP15;CG12133;Dmel\\CG12133;Dmel_CG12133;SP15", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A1Z824", "url": "https://www.uniprot.org/uniprotkb/A1Z824" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1Z824", "url": "https://www.uniprot.org/uniprotkb/A1Z824" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1Z824", "url": "https://www.uniprot.org/uniprotkb/A1Z824" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1Z824", "url": "https://www.uniprot.org/uniprotkb/A1Z824" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A1Z824", "url": "https://www.uniprot.org/uniprotkb/A1Z824" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z885-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z885", "url": "https://www.uniprot.org/uniprotkb/A1Z885" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 198, "chemical_mass": 23229.0, "gene_names": "Dmel\\CG33477;CG33477;Dmel\\CG33477;Dmel_CG33477", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8D1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 899, "chemical_mass": 101471.0, "gene_names": "Pex6;CG11919;CG30019;DmCG11919;DmelPex6;Dmel\\CG11919;Dmel_CG11919;PEX6;Pex6", "protein_name": "Peroxisomal ATPase PEX6", "disease": [ { "disease_id": "DOID:0080377", "name": "peroxisomal biogenesis disorder", "description": "A peroxisomal biogenesis disorder that has_material_basis_in defects in PEX genes.", "url": "https://disease-ontology.org/term/DOID:0080377", "evidence": [ { "id": "0080377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080377" } ], "weight": 0.0 }, { "disease_id": "DOID:0080479", "name": "peroxisome biogenesis disorder 4A", "description": "A Zellweger syndrome that has_material_basis_in homozygous or compound heterozygous mutation in the PEX6 gene on chromosome 6p21.1.", "url": "https://disease-ontology.org/term/DOID:0080479", "evidence": [ { "id": "0080479", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080479" } ], "weight": 0.0 }, { "disease_id": "DOID:0080624", "name": "Heimler syndrome 2", "description": "A peroxisomal biogenesis disorder that is characterized by sensorineural hearing loss, generalised enamel hypoplasia of the permanent dentition with normal primary dentition, and nail defects and has_material_basis_in compound heterozygous mutation in the PEX6 gene on chromosome 6p21.", "url": "https://disease-ontology.org/term/DOID:0080624", "evidence": [ { "id": "0080624", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080624" } ], "weight": 0.0 }, { "disease_id": "DOID:0081433", "name": "Peroxisome biogenesis disorder 4B", "description": "A peroxisomal biogenesis disorder that is characterized by the overlapping phenotypes of neonatal adrenoleukodystrophy and infantile Refsum disease and that has_material_basis_in homozygous or compound heterozygous mutation in the PEX6 gene on chromosome 6p21.1, or overexpression of a heterozygous mutation in PEX6 due to allelic expression imbalance resulting from a polymorphism on the mutant allele in the PEX6 3-prime UTR.", "url": "https://disease-ontology.org/term/DOID:0081433", "evidence": [ { "id": "0081433", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081433" } ], "weight": 0.0 }, { "disease_id": "DOID:906", "name": "peroxisomal disease", "description": "An inherited metabolic disorder that involves peroxisome malfunction.", "url": "https://disease-ontology.org/term/DOID:906", "evidence": [ { "id": "906", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:906" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ubiquitin-modified protein reader activity", "id": "GO:0140036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140036", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" }, { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein unfolding", "id": "GO:0043335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043335", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" }, { "name": "peroxisome organization", "id": "GO:0007031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007031", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix", "id": "GO:0016558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016558", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" }, { "name": "protein import into peroxisome matrix, receptor recycling", "id": "GO:0016562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016562", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" } ], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A1Z8D1", "url": "https://www.uniprot.org/uniprotkb/A1Z8D1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8E3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8E3", "url": "https://www.uniprot.org/uniprotkb/A1Z8E3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 165, "chemical_mass": 18881.0, "gene_names": "Obp47a;47a;CG12944;DmelObp47a;Dmel\\CG12944;Dmel_CG12944;Obp47a", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z8E3", "url": "https://www.uniprot.org/uniprotkb/A1Z8E3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1Z8E3", "url": "https://www.uniprot.org/uniprotkb/A1Z8E3" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A1Z8E3", "url": "https://www.uniprot.org/uniprotkb/A1Z8E3" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A1Z8E3", "url": "https://www.uniprot.org/uniprotkb/A1Z8E3" } ], "pmid": "" } ], "molecular_function": [ { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A1Z8E3", "url": "https://www.uniprot.org/uniprotkb/A1Z8E3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8G3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8G3", "url": "https://www.uniprot.org/uniprotkb/A1Z8G3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 120, "chemical_mass": 13205.0, "gene_names": "cg13227;CG13227;Dmel\\CG13227;Dmel_CG13227;cg13227", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8G8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8G8", "url": "https://www.uniprot.org/uniprotkb/A1Z8G8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 237, "chemical_mass": 24055.0, "gene_names": "Dmel\\CG13226;CG13226;Dmel\\CG13226;Dmel_CG13226", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8I9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8I9", "url": "https://www.uniprot.org/uniprotkb/A1Z8I9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 199, "chemical_mass": 21889.0, "gene_names": "Obp47b;CG13208;DmelObp47b;Dmel\\CG13208;Dmel_CG13208;Obp47b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z8I9", "url": "https://www.uniprot.org/uniprotkb/A1Z8I9" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A1Z8I9", "url": "https://www.uniprot.org/uniprotkb/A1Z8I9" } ], "pmid": "" } ], "molecular_function": [ { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A1Z8I9", "url": "https://www.uniprot.org/uniprotkb/A1Z8I9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8J8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8J8", "url": "https://www.uniprot.org/uniprotkb/A1Z8J8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 253, "chemical_mass": 25707.0, "gene_names": "Dmel\\CG30025;CG30025;Dmel\\CG30025;Dmel_CG30025;SP215", "protein_name": "trypsin", "disease": [ { "disease_id": "DOID:0110057", "name": "amelogenesis imperfecta type 2A1", "description": "An amelogenesis imperfecta that has_material_basis_in homozygous mutation in the kallikrein-4 gene (KLK4) on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0110057", "evidence": [ { "id": "0110057", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110057" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A1Z8J8", "url": "https://www.uniprot.org/uniprotkb/A1Z8J8" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "A1Z8J8", "url": "https://www.uniprot.org/uniprotkb/A1Z8J8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z8J8", "url": "https://www.uniprot.org/uniprotkb/A1Z8J8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1Z8J8", "url": "https://www.uniprot.org/uniprotkb/A1Z8J8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8J9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8J9", "url": "https://www.uniprot.org/uniprotkb/A1Z8J9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 81, "chemical_mass": 9546.0, "gene_names": "Dmel\\CG13202;CG13202;Dmel\\CG13202;Dmel_CG13202", "protein_name": "Dynein attachment factor N-terminal domain-containing protein", "disease": [ { "disease_id": "DOID:0110621", "name": "primary ciliary dyskinesia 17", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with inner and outer dynein arm defect, early infantile onset of respiratory distress, and variable occurence of laterality defects and has_material_basis_in homozygous mutation in the CCDC103 gene on chromosome 17q21.", "url": "https://disease-ontology.org/term/DOID:0110621", "evidence": [ { "id": "0110621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110621" } ], "weight": 0.0 }, { "disease_id": "DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube.", "url": "https://disease-ontology.org/term/DOID:9562", "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A1Z8J9", "url": "https://www.uniprot.org/uniprotkb/A1Z8J9" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A1Z8J9", "url": "https://www.uniprot.org/uniprotkb/A1Z8J9" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "A1Z8J9", "url": "https://www.uniprot.org/uniprotkb/A1Z8J9" } ], "pmid": "" } ], "cellular_component": [ { "name": "outer dynein arm", "id": "GO:0036157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036157", "evidence": [ { "database": "UniProtKB", "id": "A1Z8J9", "url": "https://www.uniprot.org/uniprotkb/A1Z8J9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8K5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8K5", "url": "https://www.uniprot.org/uniprotkb/A1Z8K5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 541, "chemical_mass": 58960.0, "gene_names": "anon-EST:Posey175;CG13203;Dmel\\CG13203;Dmel_CG13203;anon-EST:Posey175", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8L5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8L5", "url": "https://www.uniprot.org/uniprotkb/A1Z8L5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 228, "chemical_mass": 25261.0, "gene_names": "Dmel\\CG30026;CG30026;Dmel\\CG30026;Dmel_CG30026", "protein_name": "Integumentary mucin C.1-like", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8N9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8N9", "url": "https://www.uniprot.org/uniprotkb/A1Z8N9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 600, "chemical_mass": 69568.0, "gene_names": "Ir48b;48b;CG13195;DmelIR48b;Dmel\\CG13195;Dmel_CG13195;IR48b;Ir48b", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "A1Z8N9", "url": "https://www.uniprot.org/uniprotkb/A1Z8N9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z8N9", "url": "https://www.uniprot.org/uniprotkb/A1Z8N9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z8N9", "url": "https://www.uniprot.org/uniprotkb/A1Z8N9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "A1Z8N9", "url": "https://www.uniprot.org/uniprotkb/A1Z8N9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8R1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1025, "chemical_mass": 113760.0, "gene_names": "exp;CG13188;Dmel\\CG13188;Dmel_CG13188;Exp;exp", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of developmental process", "id": "GO:0050793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050793", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" }, { "name": "trachea morphogenesis", "id": "GO:0060439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060439", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" }, { "name": "post-embryonic development", "id": "GO:0009791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009791", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" }, { "name": "regulation of multicellular organismal process", "id": "GO:0051239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051239", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" }, { "name": "chitin-based embryonic cuticle biosynthetic process", "id": "GO:0008362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008362", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" }, { "name": "cytoplasmic side of apical plasma membrane", "id": "GO:0098592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098592", "evidence": [ { "database": "UniProtKB", "id": "A1Z8R1", "url": "https://www.uniprot.org/uniprotkb/A1Z8R1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z8R1-1", "start_pos": "957", "end_pos": "957", "site_lbl": "Thr957", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 957, "start_aa": "Thr", "end_pos": 957, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr957", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8R1-1", "start_pos": "984", "end_pos": "984", "site_lbl": "Thr984", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 984, "start_aa": "Thr", "end_pos": 984, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr984", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8U0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2396, "chemical_mass": 279578.0, "gene_names": "Prp8;A1Z8U0;CG8877;Dmel\\CG8877;Dmel_CG8877;E-2e;Prp8;prp8", "protein_name": "Pre-mRNA-processing-splicing factor 8", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0110403", "name": "retinitis pigmentosa 13", "description": "A retinitis pigmentosa that has_material_basis_in mutations in the PRPF8 gene on chromosome 17p13.3.", "url": "https://disease-ontology.org/term/DOID:0110403", "evidence": [ { "id": "0110403", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110403" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "pre-mRNA intronic binding", "id": "GO:0097157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097157", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "U2 snRNA binding", "id": "GO:0030620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "snRNA binding", "id": "GO:0017069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017069", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "U6 snRNA binding", "id": "GO:0017070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "U5 snRNA binding", "id": "GO:0030623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030623", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "small nuclear ribonucleoprotein complex", "id": "GO:0030532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030532", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "U5 snRNP", "id": "GO:0005682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005682", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" } ], "biological_process": [ { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" }, { "name": "ventral cord development", "id": "GO:0007419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007419", "evidence": [ { "database": "UniProtKB", "id": "A1Z8U0", "url": "https://www.uniprot.org/uniprotkb/A1Z8U0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8Y8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y8", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 166, "chemical_mass": 18966.0, "gene_names": "Cpr49Ad;CG8836;Cpr49Ad;Dmel\\CG8836;Dmel_CG8836", "protein_name": "", "disease": [], "molecular_function": [ { "name": "structural constituent of chitin-based larval cuticle", "id": "GO:0008010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008010", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y8", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y8" } ], "pmid": "" } ], "biological_process": [ { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y8", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y8" } ], "pmid": "" } ], "cellular_component": [ { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y8", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z8Z8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8Z8", "url": "https://www.uniprot.org/uniprotkb/A1Z8Z8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 467, "chemical_mass": 51331.0, "gene_names": "Dmel\\CG13157;CG13157;Dmel\\CG13157;Dmel_CG13157", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z8Z8-1", "start_pos": "272", "end_pos": "272", "site_lbl": "Thr272", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 272, "start_aa": "Thr", "end_pos": 272, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr272", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8Z8-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z910-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z910", "url": "https://www.uniprot.org/uniprotkb/A1Z910" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 633, "chemical_mass": 73797.0, "gene_names": "Nepl10;CG8550;Dmel\\CG8550;Dmel_CG8550;Nepl10", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z910", "url": "https://www.uniprot.org/uniprotkb/A1Z910" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1Z910", "url": "https://www.uniprot.org/uniprotkb/A1Z910" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z931-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z931", "url": "https://www.uniprot.org/uniprotkb/A1Z931" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 225, "chemical_mass": 26208.0, "gene_names": "Dmel\\CG33792;CG33792;Dmel\\CG33792;Dmel_CG33792", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z959-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z959", "url": "https://www.uniprot.org/uniprotkb/A1Z959" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 263, "chemical_mass": 29726.0, "gene_names": "Dmel\\CG30486;CG30486;Dmel\\CG30486;Dmel_CG30486", "protein_name": "SCP domain-containing protein", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "A1Z959", "url": "https://www.uniprot.org/uniprotkb/A1Z959" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z959", "url": "https://www.uniprot.org/uniprotkb/A1Z959" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1Z959", "url": "https://www.uniprot.org/uniprotkb/A1Z959" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z968-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z968", "url": "https://www.uniprot.org/uniprotkb/A1Z968" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1488, "chemical_mass": 162869.0, "gene_names": "NAT1;CG3845;Dmel\\CG3845;Dmel_CG3845;NAT1;Nat1;dNAT1;l(2)01424", "protein_name": "Eukaryotic translation initiation factor 4 gamma 2", "disease": [ { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A1Z968", "url": "https://www.uniprot.org/uniprotkb/A1Z968" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A1Z968", "url": "https://www.uniprot.org/uniprotkb/A1Z968" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A1Z968", "url": "https://www.uniprot.org/uniprotkb/A1Z968" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A1Z968", "url": "https://www.uniprot.org/uniprotkb/A1Z968" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "A1Z968", "url": "https://www.uniprot.org/uniprotkb/A1Z968" } ], "pmid": "" } ], "cellular_component": [ { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "A1Z968", "url": "https://www.uniprot.org/uniprotkb/A1Z968" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z968-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Thr105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 105, "start_aa": "Thr", "end_pos": 105, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr105", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z968-1", "start_pos": "115", "end_pos": "115", "site_lbl": "Thr115", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A1Z968", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A1Z968" } ] } ] }, { "uniprot_canonical_ac": "A1Z968-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Thr431", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 431, "start_aa": "Thr", "end_pos": 431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr431", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z968-1", "start_pos": "97", "end_pos": "97", "site_lbl": "Ser97", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 97, "start_aa": "Ser", "end_pos": 97, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser97", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A1Z968", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A1Z968" } ] } ] }, { "uniprot_canonical_ac": "A1Z968-1", "start_pos": "997", "end_pos": "997", "site_lbl": "Thr997", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 997, "start_aa": "Thr", "end_pos": 997, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr997", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z977-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z977", "url": "https://www.uniprot.org/uniprotkb/A1Z977" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 20927.0, "gene_names": "Dmel\\CG33798;BP1039;CG33798;Dmel\\CG33798;Dmel_CG33798", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9D0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9D0", "url": "https://www.uniprot.org/uniprotkb/A1Z9D0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 83, "chemical_mass": 9564.0, "gene_names": "BcDNA:AT19876;BcDNA:AT19876;CG30065;Dmel\\CG30065;Dmel_CG30065", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9F4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9F4", "url": "https://www.uniprot.org/uniprotkb/A1Z9F4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 490, "chemical_mass": 54793.0, "gene_names": "Nadk1b;CG30063;CG33156;CG6152;Dmel\\CG33156;Dmel_CG33156;NADK;Nadk1b", "protein_name": "NAD(+) kinase", "disease": [], "biological_process": [ { "name": "NADP+ biosynthetic process", "id": "GO:0006741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006741", "evidence": [ { "database": "UniProtKB", "id": "A1Z9F4", "url": "https://www.uniprot.org/uniprotkb/A1Z9F4" } ], "pmid": "" }, { "name": "NAD+ metabolic process", "id": "GO:0019674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019674", "evidence": [ { "database": "UniProtKB", "id": "A1Z9F4", "url": "https://www.uniprot.org/uniprotkb/A1Z9F4" } ], "pmid": "" } ], "molecular_function": [ { "name": "NAD+ kinase activity", "id": "GO:0003951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003951", "evidence": [ { "database": "UniProtKB", "id": "A1Z9F4", "url": "https://www.uniprot.org/uniprotkb/A1Z9F4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z9F4", "url": "https://www.uniprot.org/uniprotkb/A1Z9F4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A1Z9F4", "url": "https://www.uniprot.org/uniprotkb/A1Z9F4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z9F4", "url": "https://www.uniprot.org/uniprotkb/A1Z9F4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9G6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9G6", "url": "https://www.uniprot.org/uniprotkb/A1Z9G6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 607, "chemical_mass": 69024.0, "gene_names": "mst101(2);CG6209;Dmel\\CG6209;Dmel_CG6209;mst101(2)", "protein_name": "Axoneme-associated protein mst101(2)", "disease": [], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A1Z9G6", "url": "https://www.uniprot.org/uniprotkb/A1Z9G6" } ], "pmid": "" } ], "cellular_component": [ { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A1Z9G6", "url": "https://www.uniprot.org/uniprotkb/A1Z9G6" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "A1Z9G6", "url": "https://www.uniprot.org/uniprotkb/A1Z9G6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9I2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9I2", "url": "https://www.uniprot.org/uniprotkb/A1Z9I2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 912, "chemical_mass": 106215.0, "gene_names": "Dmel\\CG30484;CG13342;CG30484;Dmel\\CG30484;Dmel_CG30484", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z9I2-1", "start_pos": "535", "end_pos": "535", "site_lbl": "Thr535", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 535, "start_aa": "Thr", "end_pos": 535, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr535", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9M0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9M0", "url": "https://www.uniprot.org/uniprotkb/A1Z9M0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 307, "chemical_mass": 34180.0, "gene_names": "Dmel\\CG18324;CG18324;Dmel\\CG18324;Dmel_CG18324", "protein_name": "Solute carrier family 25 member 35", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M0", "url": "https://www.uniprot.org/uniprotkb/A1Z9M0" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M0", "url": "https://www.uniprot.org/uniprotkb/A1Z9M0" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial transmembrane transport", "id": "GO:1990542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990542", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M0", "url": "https://www.uniprot.org/uniprotkb/A1Z9M0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9M6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 549, "chemical_mass": 60838.0, "gene_names": "VGAT;CG8394.2;CG8394;Dmel\\CG8394;Dmel_CG8394;VGAT;VIAAT;Vgat;dVGAT;vGAT", "protein_name": "Vesicular inhibitory amino acid transporter", "disease": [ { "disease_id": "DOID:0060170", "name": "generalized epilepsy with febrile seizures plus", "description": "An idiopathic generalized epilepsy that is characterized by febrile seizures often with accessory afebrile generalized tonic-clonic seizures with childhood onset.", "url": "https://disease-ontology.org/term/DOID:0060170", "evidence": [ { "id": "0060170", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060170" } ], "weight": 0.0 }, { "disease_id": "DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood.", "url": "https://disease-ontology.org/term/DOID:0112202", "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "glycine transmembrane transporter activity", "id": "GO:0015187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015187", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid transmembrane transporter activity", "id": "GO:0015185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015185", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid:proton antiporter activity", "id": "GO:0140800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140800", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" } ], "biological_process": [ { "name": "glycine transport", "id": "GO:0015816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015816", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "sleep", "id": "GO:0030431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030431", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "visual behavior", "id": "GO:0007632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007632", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid transport", "id": "GO:0015812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015812", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid import", "id": "GO:0051939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051939", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "neurotransmitter loading into synaptic vesicle", "id": "GO:0098700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098700", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "synaptic transmission, GABAergic", "id": "GO:0051932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051932", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" } ], "cellular_component": [ { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "inhibitory synapse", "id": "GO:0060077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060077", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "dendrite terminus", "id": "GO:0044292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044292", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "A1Z9M6", "url": "https://www.uniprot.org/uniprotkb/A1Z9M6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9Q6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q6", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 196, "chemical_mass": 22225.0, "gene_names": "Obp50e;CG13939;DmelObp50e;Dmel\\CG13939;Dmel_CG13939;Obp50e", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q6", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q6" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q6", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q6" } ], "pmid": "" } ], "molecular_function": [ { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q6", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9Q8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 504, "chemical_mass": 56343.0, "gene_names": "Dh44-R1;CG8422;DH-R;DH44-R1;DH44R1;DH[[44]]-R1;Dh44-R1;Dh44R1;DmeCG8422;Dmel\\CG8422;Dmel_CG8422;anon-WO0170980.100;anon-WO0170980.101", "protein_name": "Diuretic hormone receptor", "disease": [ { "disease_id": "DOID:0050696", "name": "fetal alcohol spectrum disorder", "description": "A specific developmental disorder and physical disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of alcohol during pregnancy.", "url": "https://disease-ontology.org/term/DOID:0050696", "evidence": [ { "id": "0050696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050696" } ], "weight": 0.0 }, { "disease_id": "DOID:0060180", "name": "colitis", "description": "An inflammatory bowel disease that involves inflammation located_in colon.", "url": "https://disease-ontology.org/term/DOID:0060180", "evidence": [ { "id": "0060180", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060180" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:12918", "name": "thromboangiitis obliterans", "description": "", "url": "https://disease-ontology.org/term/DOID:12918", "evidence": [ { "id": "12918", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12918" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 }, { "disease_id": "DOID:3877", "name": "functional colonic disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3877", "evidence": [ { "id": "3877", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3877" } ], "weight": 0.0 }, { "disease_id": "DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip.", "url": "https://disease-ontology.org/term/DOID:4483", "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ], "weight": 0.0 }, { "disease_id": "DOID:767", "name": "muscular atrophy", "description": "", "url": "https://disease-ontology.org/term/DOID:767", "evidence": [ { "id": "767", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:767" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9778", "name": "irritable bowel syndrome", "description": "An intestinal disease that is characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause.", "url": "https://disease-ontology.org/term/DOID:9778", "evidence": [ { "id": "9778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9778" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" } ], "biological_process": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" }, { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" }, { "name": "G protein-coupled peptide receptor activity", "id": "GO:0008528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" }, { "name": "calcitonin receptor activity", "id": "GO:0004948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004948", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" }, { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" }, { "name": "diuretic hormone receptor activity", "id": "GO:0008036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008036", "evidence": [ { "database": "UniProtKB", "id": "A1Z9Q8", "url": "https://www.uniprot.org/uniprotkb/A1Z9Q8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9S6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9S6", "url": "https://www.uniprot.org/uniprotkb/A1Z9S6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3257, "chemical_mass": 355974.0, "gene_names": "Su(var)2-HP2;CG12864;Dmel\\CG12864;Dmel_CG12864;HP2;Hp2;SU(VAR)2-HP2;Su(var)2-HP2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S6", "url": "https://www.uniprot.org/uniprotkb/A1Z9S6" } ], "pmid": "" } ], "cellular_component": [ { "name": "condensed chromosome", "id": "GO:0000793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000793", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S6", "url": "https://www.uniprot.org/uniprotkb/A1Z9S6" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S6", "url": "https://www.uniprot.org/uniprotkb/A1Z9S6" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S6", "url": "https://www.uniprot.org/uniprotkb/A1Z9S6" } ], "pmid": "" } ], "biological_process": [ { "name": "mitotic chromosome condensation", "id": "GO:0007076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007076", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S6", "url": "https://www.uniprot.org/uniprotkb/A1Z9S6" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S6", "url": "https://www.uniprot.org/uniprotkb/A1Z9S6" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S6", "url": "https://www.uniprot.org/uniprotkb/A1Z9S6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z9S6-1", "start_pos": "2346", "end_pos": "2346", "site_lbl": "Thr2346", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2346, "start_aa": "Thr", "end_pos": 2346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2346", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z9S6-1", "start_pos": "2348", "end_pos": "2348", "site_lbl": "Thr2348", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2348, "start_aa": "Thr", "end_pos": 2348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2348", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z9S6-1", "start_pos": "855", "end_pos": "855", "site_lbl": "Thr855", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 855, "start_aa": "Thr", "end_pos": 855, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr855", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9S8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9S8", "url": "https://www.uniprot.org/uniprotkb/A1Z9S8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 437, "chemical_mass": 51083.0, "gene_names": "Dmel\\CG12863;CG12863;Dmel\\CG12863;Dmel_CG12863", "protein_name": "Zinc finger CCHC domain-containing protein 4", "disease": [], "biological_process": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S8", "url": "https://www.uniprot.org/uniprotkb/A1Z9S8" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S8", "url": "https://www.uniprot.org/uniprotkb/A1Z9S8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S8", "url": "https://www.uniprot.org/uniprotkb/A1Z9S8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S8", "url": "https://www.uniprot.org/uniprotkb/A1Z9S8" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S8", "url": "https://www.uniprot.org/uniprotkb/A1Z9S8" } ], "pmid": "" }, { "name": "rRNA (adenine-N6-)-methyltransferase activity", "id": "GO:0008988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008988", "evidence": [ { "database": "UniProtKB", "id": "A1Z9S8", "url": "https://www.uniprot.org/uniprotkb/A1Z9S8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1Z9V4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9V4", "url": "https://www.uniprot.org/uniprotkb/A1Z9V4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 224, "chemical_mass": 25025.0, "gene_names": "CT28709;CG10205;CT28709;Dmel\\CG10205;Dmel_CG10205", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZA17-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA17", "url": "https://www.uniprot.org/uniprotkb/A1ZA17" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 594, "chemical_mass": 69505.0, "gene_names": "Ir52d;52d;CG12961;CG30464;DmelIR52d;Dmel\\CG30464;Dmel_CG30464;IR52d;Ir52d", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "A1ZA17", "url": "https://www.uniprot.org/uniprotkb/A1ZA17" } ], "pmid": "" }, { "name": "reproductive behavior", "id": "GO:0019098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019098", "evidence": [ { "database": "UniProtKB", "id": "A1ZA17", "url": "https://www.uniprot.org/uniprotkb/A1ZA17" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1ZA17", "url": "https://www.uniprot.org/uniprotkb/A1ZA17" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1ZA17", "url": "https://www.uniprot.org/uniprotkb/A1ZA17" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "A1ZA17", "url": "https://www.uniprot.org/uniprotkb/A1ZA17" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZA22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA22", "url": "https://www.uniprot.org/uniprotkb/A1ZA22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 455, "chemical_mass": 50671.0, "gene_names": "eIF2Bgamma;CG8190;Dmel\\CG8190;Dmel_CG8190;eIF2B-gamma;eIF2Bgamma", "protein_name": "Translation initiation factor eIF2B subunit gamma", "disease": [ { "disease_id": "DOID:0060868", "name": "leukoencephalopathy with vanishing white matter", "description": "A leukodystrophy characterized by variable neurologic features resulting from deficiency in astrocyte maturation, including progressive cerebellar ataxia, spasticity, and cognitive impairment associated with white matter lesions on brain imaging with onset from early infancy to adulthood.", "url": "https://disease-ontology.org/term/DOID:0060868", "evidence": [ { "id": "0060868", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060868" } ], "weight": 0.0 }, { "disease_id": "DOID:0070372", "name": "leukoencephalopathy with vanishing white matter 3", "description": "A leukoencephalopathy with vanishing white matter that has_material_basis_in homozygous or compound heterozygous mutation in the EIF2B3 gene on chromosome 1p34.", "url": "https://disease-ontology.org/term/DOID:0070372", "evidence": [ { "id": "0070372", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070372" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cytoplasmic translational initiation", "id": "GO:0002183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002183", "evidence": [ { "database": "UniProtKB", "id": "A1ZA22", "url": "https://www.uniprot.org/uniprotkb/A1ZA22" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "A1ZA22", "url": "https://www.uniprot.org/uniprotkb/A1ZA22" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A1ZA22", "url": "https://www.uniprot.org/uniprotkb/A1ZA22" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A1ZA22", "url": "https://www.uniprot.org/uniprotkb/A1ZA22" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2B complex", "id": "GO:0005851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005851", "evidence": [ { "database": "UniProtKB", "id": "A1ZA22", "url": "https://www.uniprot.org/uniprotkb/A1ZA22" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A1ZA22", "url": "https://www.uniprot.org/uniprotkb/A1ZA22" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A1ZA22", "url": "https://www.uniprot.org/uniprotkb/A1ZA22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZA41-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA41", "url": "https://www.uniprot.org/uniprotkb/A1ZA41" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 287, "chemical_mass": 33171.0, "gene_names": "Dmel\\CG33461;CG30086;CG33461;CG8215;Dmel\\CG33461;Dmel_CG33461;SP239;SP41", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A1ZA41", "url": "https://www.uniprot.org/uniprotkb/A1ZA41" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1ZA41", "url": "https://www.uniprot.org/uniprotkb/A1ZA41" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1ZA41", "url": "https://www.uniprot.org/uniprotkb/A1ZA41" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A1ZA41", "url": "https://www.uniprot.org/uniprotkb/A1ZA41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZA51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA51", "url": "https://www.uniprot.org/uniprotkb/A1ZA51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 488, "chemical_mass": 55228.0, "gene_names": "HDC06631;BP1080;CG33465;CR33465;Dmel\\CG33465;Dmel_CG33465;HDC06631;SPH241", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1ZA51", "url": "https://www.uniprot.org/uniprotkb/A1ZA51" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1ZA51", "url": "https://www.uniprot.org/uniprotkb/A1ZA51" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A1ZA51", "url": "https://www.uniprot.org/uniprotkb/A1ZA51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZA86-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZA86", "url": "https://www.uniprot.org/uniprotkb/A1ZA86" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 314, "chemical_mass": 35436.0, "gene_names": "Dmel\\CG8401;CG8401;Dmel\\CG8401;Dmel_CG8401", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A1ZA86", "url": "https://www.uniprot.org/uniprotkb/A1ZA86" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1ZA86", "url": "https://www.uniprot.org/uniprotkb/A1ZA86" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAC2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAC2", "url": "https://www.uniprot.org/uniprotkb/A1ZAC2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 192, "chemical_mass": 21405.0, "gene_names": "Dmel\\CG7786;CG7786;DM33;DM7;Dmel\\CG7786;Dmel_CG7786", "protein_name": "BZIP domain-containing protein", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZAC2", "url": "https://www.uniprot.org/uniprotkb/A1ZAC2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A1ZAC2", "url": "https://www.uniprot.org/uniprotkb/A1ZAC2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A1ZAC2", "url": "https://www.uniprot.org/uniprotkb/A1ZAC2" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A1ZAC2", "url": "https://www.uniprot.org/uniprotkb/A1ZAC2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A1ZAC2", "url": "https://www.uniprot.org/uniprotkb/A1ZAC2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAP0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAP0", "url": "https://www.uniprot.org/uniprotkb/A1ZAP0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 498, "chemical_mass": 57268.0, "gene_names": "SmydA-6;CG9642;Dmel\\CG9642;Dmel_CG9642;SmydA-6", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A1ZAP0", "url": "https://www.uniprot.org/uniprotkb/A1ZAP0" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A1ZAP0", "url": "https://www.uniprot.org/uniprotkb/A1ZAP0" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A1ZAP0", "url": "https://www.uniprot.org/uniprotkb/A1ZAP0" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A1ZAP0", "url": "https://www.uniprot.org/uniprotkb/A1ZAP0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAR2", "url": "https://www.uniprot.org/uniprotkb/A1ZAR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 338, "chemical_mass": 40056.0, "gene_names": "Dmel\\CG17287;CG17287;Dmel\\CG17287;Dmel_CG17287", "protein_name": "Palmitoyltransferase", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A1ZAR2", "url": "https://www.uniprot.org/uniprotkb/A1ZAR2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A1ZAR2", "url": "https://www.uniprot.org/uniprotkb/A1ZAR2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1ZAR2", "url": "https://www.uniprot.org/uniprotkb/A1ZAR2" } ], "pmid": "" } ], "biological_process": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A1ZAR2", "url": "https://www.uniprot.org/uniprotkb/A1ZAR2" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A1ZAR2", "url": "https://www.uniprot.org/uniprotkb/A1ZAR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAR4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAR4", "url": "https://www.uniprot.org/uniprotkb/A1ZAR4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 189, "chemical_mass": 19248.0, "gene_names": "Dmel\\CG30457;CG17288;CG30457-PA;CG30457;Dmel\\CG30457;Dmel_CG30457", "protein_name": "Skin secretory protein xP2-like", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAS8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAS8", "url": "https://www.uniprot.org/uniprotkb/A1ZAS8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 754, "chemical_mass": 83892.0, "gene_names": "EDTP;BcDNA:LD23181;CG6542;D-EDTP;Dmel\\CG6542;Dmel_CG6542;EDTP;anon-WO0118547.124", "protein_name": "", "disease": [ { "disease_id": "DOID:0111223", "name": "centronuclear myopathy 1", "description": "An autosomal dominant centronuclear myopathy characterized by slowly progressive muscle wasting and weakness involving mainly the limb girdle, trunk, and neck muscles that has_material_basis_in heterozygous mutation in DNM2 on 19p13.2.", "url": "https://disease-ontology.org/term/DOID:0111223", "evidence": [ { "id": "0111223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111223" } ], "weight": 0.0 } ], "biological_process": [ { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "A1ZAS8", "url": "https://www.uniprot.org/uniprotkb/A1ZAS8" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "A1ZAS8", "url": "https://www.uniprot.org/uniprotkb/A1ZAS8" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate phosphatase activity", "id": "GO:0004438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004438", "evidence": [ { "database": "UniProtKB", "id": "A1ZAS8", "url": "https://www.uniprot.org/uniprotkb/A1ZAS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAW6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAW6", "url": "https://www.uniprot.org/uniprotkb/A1ZAW6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 155, "chemical_mass": 17426.0, "gene_names": "BcDNA:RE11282;BcDNA:RE11282;CG30105;Dmel\\CG30105;Dmel_CG30105", "protein_name": "", "disease": [ { "disease_id": "DOID:0050629", "name": "Aicardi-Goutieres syndrome", "description": "A syndrome that is a genetically heterogeneous encephalopathy characterized in its most severe form by cerebral atrophy, leukodystrophy, intracranial calcifications, chronic cerebrospinal fluid lymphocytosis, increased CSF alpha-interferon, and negative serologic investigations for common prenatal infections.", "url": "https://disease-ontology.org/term/DOID:0050629", "evidence": [ { "id": "0050629", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050629" } ], "weight": 0.0 } ], "biological_process": [ { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW6", "url": "https://www.uniprot.org/uniprotkb/A1ZAW6" } ], "pmid": "" } ], "cellular_component": [ { "name": "ribonuclease H2 complex", "id": "GO:0032299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032299", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW6", "url": "https://www.uniprot.org/uniprotkb/A1ZAW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAW7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 702, "chemical_mass": 76809.0, "gene_names": "ND-51L1;CG11423;Dmel\\CG11423;Dmel_CG11423;ND-51L1;ND51L1;NUBM;dNDUFV1B", "protein_name": "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial", "disease": [ { "disease_id": "DOID:0060536", "name": "mitochondrial complex I deficiency", "description": "A mitochondrial metabolism disease characterized by a wide range of manifestations including marked and often fatal lactic acidosis, cardiomyopathy, leukoencephalopathy, pure myopathy and hepatopathy with tubulopathy. Among the numerous clinical phenotypes observed are Leigh syndrome, Leber hereditary optic neuropathy and MELAS syndrome. It can have material basis in mutations in multiple different genes, both nuclear-encoded and mitochondrial-encoded.", "url": "https://disease-ontology.org/term/DOID:0060536", "evidence": [ { "id": "0060536", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060536" } ], "weight": 0.0 }, { "disease_id": "DOID:0112082", "name": "nuclear type mitochondrial complex I deficiency 4", "description": "A nuclear type mitochondrial complex I deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the NDUFV1 gene on chromosome 11q13.2.", "url": "https://disease-ontology.org/term/DOID:0112082", "evidence": [ { "id": "0112082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112082" } ], "weight": 0.0 }, { "disease_id": "DOID:700", "name": "mitochondrial metabolism disease", "description": "An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.", "url": "https://disease-ontology.org/term/DOID:700", "evidence": [ { "id": "700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:700" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "pmid": "" }, { "name": "NADH dehydrogenase (ubiquinone) activity", "id": "GO:0008137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008137", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "pmid": "" }, { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW7", "url": "https://www.uniprot.org/uniprotkb/A1ZAW7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZAW7-1", "start_pos": "210", "end_pos": "210", "site_lbl": "Thr210", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 210, "start_aa": "Thr", "end_pos": 210, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr210", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW7-1", "start_pos": "246", "end_pos": "246", "site_lbl": "Thr246", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAX7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAX7", "url": "https://www.uniprot.org/uniprotkb/A1ZAX7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 126, "chemical_mass": 13634.0, "gene_names": "CG14481;CG14481;CG42562;Dmel\\CG42562;Dmel_CG42562", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZAZ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAZ2", "url": "https://www.uniprot.org/uniprotkb/A1ZAZ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 894, "chemical_mass": 99035.0, "gene_names": "Sardh;CG6385;Dmel\\CG6385;Dmel_CG6385;Sardh;sardh", "protein_name": "", "disease": [ { "disease_id": "DOID:0112307", "name": "sarcosinemia", "description": "An amino acid metabolic disorder characterized by increased concentrations of sarcosine in plasma and urine that has_material_basis_in homozygous or compound heterozygous mutation in the SARDH gene on chromosome 9q34.2.", "url": "https://disease-ontology.org/term/DOID:0112307", "evidence": [ { "id": "0112307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112307" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZAZ2", "url": "https://www.uniprot.org/uniprotkb/A1ZAZ2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A1ZAZ2", "url": "https://www.uniprot.org/uniprotkb/A1ZAZ2" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A1ZAZ2", "url": "https://www.uniprot.org/uniprotkb/A1ZAZ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "sarcosine dehydrogenase activity", "id": "GO:0008480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008480", "evidence": [ { "database": "UniProtKB", "id": "A1ZAZ2", "url": "https://www.uniprot.org/uniprotkb/A1ZAZ2" } ], "pmid": "" } ], "biological_process": [ { "name": "sarcosine catabolic process", "id": "GO:1901053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901053", "evidence": [ { "database": "UniProtKB", "id": "A1ZAZ2", "url": "https://www.uniprot.org/uniprotkb/A1ZAZ2" } ], "pmid": "" }, { "name": "S-adenosylmethionine cycle", "id": "GO:0033353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033353", "evidence": [ { "database": "UniProtKB", "id": "A1ZAZ2", "url": "https://www.uniprot.org/uniprotkb/A1ZAZ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZB21-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB21", "url": "https://www.uniprot.org/uniprotkb/A1ZB21" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 253, "chemical_mass": 25957.0, "gene_names": "Dmel\\CG5767;CG5767;CT18118;Dmel\\CG5767;Dmel_CG5767", "protein_name": "Protein TsetseEP domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZB55-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB55", "url": "https://www.uniprot.org/uniprotkb/A1ZB55" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 188, "chemical_mass": 21553.0, "gene_names": "Dmel\\CG18537;CG18537;Dmel\\CG18537;Dmel_CG18537", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZB70-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB70", "url": "https://www.uniprot.org/uniprotkb/A1ZB70" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 222, "chemical_mass": 25310.0, "gene_names": "GstE5;CG17527;DmGSTE5;Dmel\\CG17527;Dmel_CG17527;GSTE5;GstE5;gstE5;gste5", "protein_name": "", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A1ZB70", "url": "https://www.uniprot.org/uniprotkb/A1ZB70" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZB70", "url": "https://www.uniprot.org/uniprotkb/A1ZB70" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A1ZB70", "url": "https://www.uniprot.org/uniprotkb/A1ZB70" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZB71-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZB71", "url": "https://www.uniprot.org/uniprotkb/A1ZB71" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 222, "chemical_mass": 25015.0, "gene_names": "GstE6;CG17530;CT38747;DmGSTE6;Dmel\\CG17530;Dmel_CG17530;E6;GSTE6;GstE6;gstE6;gste6", "protein_name": "", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A1ZB71", "url": "https://www.uniprot.org/uniprotkb/A1ZB71" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "A1ZB71", "url": "https://www.uniprot.org/uniprotkb/A1ZB71" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZB71", "url": "https://www.uniprot.org/uniprotkb/A1ZB71" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A1ZB71", "url": "https://www.uniprot.org/uniprotkb/A1ZB71" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBF7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBF7", "url": "https://www.uniprot.org/uniprotkb/A1ZBF7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 904, "chemical_mass": 104348.0, "gene_names": "Vha100-3;BcDNA:AT03238;CG30329;Dmel\\CG30329;Dmel_CG30329;Vha100-3;vha100-3", "protein_name": "V-type proton ATPase subunit a", "disease": [ { "disease_id": "DOID:0061166", "name": "autosomal recessive distal renal tubular acidosis 3 with or without sensorineural hearing loss", "description": "A renal tubular transport disease characterized by the failure of the kidney to produce an appropriately acid urine in the presence of systemic metabolic acidosis or after acid loading, due to failure of hydrogen ion secretion or bicarbonate reabsorption in the distal nephron that has_material_basis_in homozygous mutation in the ATP6N1B gene on chromosome 7q34.", "url": "https://disease-ontology.org/term/DOID:0061166", "evidence": [ { "id": "0061166", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061166" } ], "weight": 0.0 }, { "disease_id": "DOID:0070390", "name": "developmental and epileptic encephalopathy 104", "description": "A developmental and epileptic encephalopathy characterized by developmental delay in the first few months of life and drug-resistant focal and generalized tonic-clonic seizures that has_material_basis_in heterozygous mutation in the ATP6V0A1 on chromosome 17q21.", "url": "https://disease-ontology.org/term/DOID:0070390", "evidence": [ { "id": "0070390", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070390" } ], "weight": 0.0 }, { "disease_id": "DOID:0110942", "name": "autosomal recessive osteopetrosis 1", "description": "An osteopetrosis characterized by autosomal recessive inheritance that has_material_basis_in homozygous or compound heterozygous mutation in the TCIRG1 gene on chromosome 11q13.2.", "url": "https://disease-ontology.org/term/DOID:0110942", "evidence": [ { "id": "0110942", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110942" } ], "weight": 0.0 }, { "disease_id": "DOID:11836", "name": "clubfoot", "description": "A bone development disease where one or both are inclined inwards, axially rotated outwards, and pointing downwards with concomitant soft tissue abnormalities.", "url": "https://disease-ontology.org/term/DOID:11836", "evidence": [ { "id": "11836", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11836" } ], "weight": 0.0 }, { "disease_id": "DOID:14219", "name": "renal tubular acidosis", "description": "A renal tubular transport disease characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic acidosis.", "url": "https://disease-ontology.org/term/DOID:14219", "evidence": [ { "id": "14219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14219" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1ZBF7", "url": "https://www.uniprot.org/uniprotkb/A1ZBF7" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase complex", "id": "GO:0016471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016471", "evidence": [ { "database": "UniProtKB", "id": "A1ZBF7", "url": "https://www.uniprot.org/uniprotkb/A1ZBF7" } ], "pmid": "" }, { "name": "vacuolar proton-transporting V-type ATPase, V0 domain", "id": "GO:0000220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000220", "evidence": [ { "database": "UniProtKB", "id": "A1ZBF7", "url": "https://www.uniprot.org/uniprotkb/A1ZBF7" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A1ZBF7", "url": "https://www.uniprot.org/uniprotkb/A1ZBF7" } ], "pmid": "" }, { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "A1ZBF7", "url": "https://www.uniprot.org/uniprotkb/A1ZBF7" } ], "pmid": "" } ], "biological_process": [ { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "A1ZBF7", "url": "https://www.uniprot.org/uniprotkb/A1ZBF7" } ], "pmid": "" }, { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "A1ZBF7", "url": "https://www.uniprot.org/uniprotkb/A1ZBF7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBI8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBI8", "url": "https://www.uniprot.org/uniprotkb/A1ZBI8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 222, "chemical_mass": 25120.0, "gene_names": "AANATL6;AANATL6;CG18606;Dmel\\CG18606;Dmel_CG18606", "protein_name": "aralkylamine N-acetyltransferase", "disease": [], "molecular_function": [ { "name": "aralkylamine N-acetyltransferase activity", "id": "GO:0004059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004059", "evidence": [ { "database": "UniProtKB", "id": "A1ZBI8", "url": "https://www.uniprot.org/uniprotkb/A1ZBI8" } ], "pmid": "" }, { "name": "N-acetyltransferase activity", "id": "GO:0008080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008080", "evidence": [ { "database": "UniProtKB", "id": "A1ZBI8", "url": "https://www.uniprot.org/uniprotkb/A1ZBI8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBM3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBM3", "url": "https://www.uniprot.org/uniprotkb/A1ZBM3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1366, "chemical_mass": 153507.0, "gene_names": "Oseg6;CG11237;Dmel\\CG11237;Dmel_CG11237;IFT144;OSEG6;OSEG;Oseg6;WDR19;Wdr19;oseg6", "protein_name": "", "disease": [ { "disease_id": "DOID:0050576", "name": "Senior-Loken syndrome", "description": "A syndrome characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease.", "url": "https://disease-ontology.org/term/DOID:0050576", "evidence": [ { "id": "0050576", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050576" } ], "weight": 0.0 }, { "disease_id": "DOID:0050876", "name": "Caroli disease", "description": "A bile duct disease that is characterized by abnormal dilatation of the intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:0050876", "evidence": [ { "id": "0050876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050876" } ], "weight": 0.0 }, { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 }, { "disease_id": "DOID:0070571", "name": "spermatogenic failure 72", "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the sperm flagella, resulting in lack of sperm motility, that has_material_basis_in homozygous mutation in the WDR19 gene on chromosome 4p14.", "url": "https://disease-ontology.org/term/DOID:0070571", "evidence": [ { "id": "0070571", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070571" } ], "weight": 0.0 }, { "disease_id": "DOID:0080806", "name": "cranioectodermal dysplasia 4", "description": "A cranioectodermal dysplasia that has_material_basis_in compound heterozygous mutation in the WDR19 gene on chromosome 4p14.", "url": "https://disease-ontology.org/term/DOID:0080806", "evidence": [ { "id": "0080806", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080806" } ], "weight": 0.0 }, { "disease_id": "DOID:0110089", "name": "asphyxiating thoracic dystrophy 5", "description": "An asphyxiating thoracic dystrophy that has_material_basis_in homozygous mutation in the WDR19 gene on chromosome 4p14.", "url": "https://disease-ontology.org/term/DOID:0110089", "evidence": [ { "id": "0110089", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110089" } ], "weight": 0.0 }, { "disease_id": "DOID:0111121", "name": "nephronophthisis 13", "description": "A nephronophthisis that has_material_basis_in homozygous or compound heterozygous mutation in the WDR19 gene on chromosome 4p14.", "url": "https://disease-ontology.org/term/DOID:0111121", "evidence": [ { "id": "0111121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111121" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM3", "url": "https://www.uniprot.org/uniprotkb/A1ZBM3" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM3", "url": "https://www.uniprot.org/uniprotkb/A1ZBM3" } ], "pmid": "" }, { "name": "intraciliary transport particle A", "id": "GO:0030991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030991", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM3", "url": "https://www.uniprot.org/uniprotkb/A1ZBM3" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM3", "url": "https://www.uniprot.org/uniprotkb/A1ZBM3" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM3", "url": "https://www.uniprot.org/uniprotkb/A1ZBM3" } ], "pmid": "" }, { "name": "intraciliary retrograde transport", "id": "GO:0035721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035721", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM3", "url": "https://www.uniprot.org/uniprotkb/A1ZBM3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBM9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBM9", "url": "https://www.uniprot.org/uniprotkb/A1ZBM9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 632, "chemical_mass": 74565.0, "gene_names": "Ir56d;56d;CG15904;DmelIR56d;Dmel\\CG15904;Dmel_CG15904;IR56d;Ir56d", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM9", "url": "https://www.uniprot.org/uniprotkb/A1ZBM9" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of taste", "id": "GO:0050912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050912", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM9", "url": "https://www.uniprot.org/uniprotkb/A1ZBM9" } ], "pmid": "" }, { "name": "proboscis extension reflex", "id": "GO:0007637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007637", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM9", "url": "https://www.uniprot.org/uniprotkb/A1ZBM9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM9", "url": "https://www.uniprot.org/uniprotkb/A1ZBM9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM9", "url": "https://www.uniprot.org/uniprotkb/A1ZBM9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM9", "url": "https://www.uniprot.org/uniprotkb/A1ZBM9" } ], "pmid": "" }, { "name": "ionotropic taste receptor activity", "id": "GO:0170021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0170021", "evidence": [ { "database": "UniProtKB", "id": "A1ZBM9", "url": "https://www.uniprot.org/uniprotkb/A1ZBM9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBM9-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Thr188", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBP7", "url": "https://www.uniprot.org/uniprotkb/A1ZBP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 137, "chemical_mass": 14828.0, "gene_names": "Obp56b;56b;CG15129;CG30129;DmelObp56b;Dmel\\CG30129;Dmel_CG30129;OBP56b;Obp56b", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP7", "url": "https://www.uniprot.org/uniprotkb/A1ZBP7" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP7", "url": "https://www.uniprot.org/uniprotkb/A1ZBP7" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP7", "url": "https://www.uniprot.org/uniprotkb/A1ZBP7" } ], "pmid": "" }, { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP7", "url": "https://www.uniprot.org/uniprotkb/A1ZBP7" } ], "pmid": "" } ], "molecular_function": [ { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP7", "url": "https://www.uniprot.org/uniprotkb/A1ZBP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBP9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBP9", "url": "https://www.uniprot.org/uniprotkb/A1ZBP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 245, "chemical_mass": 28055.0, "gene_names": "Obp56c;56c;CG15129;CG30128;DmelObp56c;Dmel\\CG30128;Dmel_CG30128;OBP56c;Obp56c", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP9", "url": "https://www.uniprot.org/uniprotkb/A1ZBP9" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP9", "url": "https://www.uniprot.org/uniprotkb/A1ZBP9" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP9", "url": "https://www.uniprot.org/uniprotkb/A1ZBP9" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP9", "url": "https://www.uniprot.org/uniprotkb/A1ZBP9" } ], "pmid": "" } ], "molecular_function": [ { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A1ZBP9", "url": "https://www.uniprot.org/uniprotkb/A1ZBP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBP9-1", "start_pos": "101", "end_pos": "101", "site_lbl": "Thr101", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 101, "start_aa": "Thr", "end_pos": 101, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr101", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1385, "chemical_mass": 154819.0, "gene_names": "18w;18-wheeler;18-w;18W;18w;CG8896;CT25100;Dmel\\CG8896;Dmel_CG8896;EP-709;Toll-2;Toll2;l(2)00053;tlr;toll-2;toll", "protein_name": "", "disease": [], "molecular_function": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "antibacterial humoral response", "id": "GO:0019731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019731", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "axis elongation", "id": "GO:0003401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003401", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "convergent extension", "id": "GO:0060026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060026", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "follicle cell of egg chamber migration", "id": "GO:0007297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007297", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "ventral cord development", "id": "GO:0007419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007419", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" }, { "name": "eggshell formation", "id": "GO:0030703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030703", "evidence": [ { "database": "UniProtKB", "id": "A1ZBR2", "url": "https://www.uniprot.org/uniprotkb/A1ZBR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBR2-1", "start_pos": "1235", "end_pos": "1235", "site_lbl": "Thr1235", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1235, "start_aa": "Thr", "end_pos": 1235, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1235", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.7" }, { "uniprot_canonical_ac": "A1ZBU6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBU6", "url": "https://www.uniprot.org/uniprotkb/A1ZBU6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 27906.0, "gene_names": "BcDNA:RE70748;BcDNA:RE70748;CG30151;Dmel\\CG30151;Dmel_CG30151", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1ZBU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBU9", "url": "https://www.uniprot.org/uniprotkb/A1ZBU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 476, "chemical_mass": 54220.0, "gene_names": "Dmel\\CG13423;CG13423;Dmel\\CG13423;Dmel_CG13423", "protein_name": "Bleomycin hydrolase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZBU9", "url": "https://www.uniprot.org/uniprotkb/A1ZBU9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A1ZBU9", "url": "https://www.uniprot.org/uniprotkb/A1ZBU9" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A1ZBU9", "url": "https://www.uniprot.org/uniprotkb/A1ZBU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1ZBV0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBV0", "url": "https://www.uniprot.org/uniprotkb/A1ZBV0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 105, "chemical_mass": 11677.0, "gene_names": "Dmel\\CG13427;CG13427;Dmel\\CG13427;Dmel_CG13427", "protein_name": "", "disease": [], "cellular_component": [ { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A1ZBV0", "url": "https://www.uniprot.org/uniprotkb/A1ZBV0" } ], "pmid": "" } ], "biological_process": [ { "name": "gastrulation", "id": "GO:0007369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007369", "evidence": [ { "database": "UniProtKB", "id": "A1ZBV0", "url": "https://www.uniprot.org/uniprotkb/A1ZBV0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8DYA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYA9", "url": "https://www.uniprot.org/uniprotkb/A8DYA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 129, "chemical_mass": 14631.0, "gene_names": "Dmel\\CG34230;CG34230;Dmel\\CG34230;Dmel_CG34230", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8DYC6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYC6", "url": "https://www.uniprot.org/uniprotkb/A8DYC6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 266, "chemical_mass": 31192.0, "gene_names": "Dmel\\CG34315;CG34315;Dmel\\CG34315;Dmel_CG34315", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8DYP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 459, "chemical_mass": 53811.0, "gene_names": "cGlr2;CG30424;Dmel\\CG30424;cGLR2;cGlr2;mdcds_18556", "protein_name": "Cyclic GMP-AMP synthase-like receptor 2", "disease": [], "molecular_function": [ { "name": "2',3'-cyclic GMP-AMP synthase activity", "id": "GO:0061501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061501", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "3',2'-cyclic GMP-AMP synthase activity", "id": "GO:0140700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140700", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" } ], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "immune response involved in response to exogenous dsRNA", "id": "GO:1902615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902615", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" }, { "name": "cGAS/STING signaling pathway", "id": "GO:0140896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140896", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8DYP7-1", "start_pos": "256", "end_pos": "256", "site_lbl": "Lys256", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "E", "comment": "Abolished binding to nucleic acid activator, leading to impaired antiviral immunity; when associated with E-267 or E-271.", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" }, { "database": "PubMed", "id": "34261128", "url": "https://glygen.org/publication/PubMed/34261128" } ] } ] }, { "uniprot_canonical_ac": "A8DYP7-1", "start_pos": "267", "end_pos": "267", "site_lbl": "Arg267", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Abolished binding to nucleic acid activator, leading to impaired antiviral immunity; when associated with E-256.", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" }, { "database": "PubMed", "id": "34261128", "url": "https://glygen.org/publication/PubMed/34261128" } ] } ] }, { "uniprot_canonical_ac": "A8DYP7-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Arg271", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Abolished binding to nucleic acid activator, leading to impaired antiviral immunity; when associated with E-256.", "evidence": [ { "database": "UniProtKB", "id": "A8DYP7", "url": "https://www.uniprot.org/uniprotkb/A8DYP7" }, { "database": "PubMed", "id": "34261128", "url": "https://glygen.org/publication/PubMed/34261128" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8DYU5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYU5", "url": "https://www.uniprot.org/uniprotkb/A8DYU5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 83, "chemical_mass": 9236.0, "gene_names": "Dmel\\CG34176;CG34176;Dmel\\CG34176;Dmel_CG34176", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8DYY2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DYY2", "url": "https://www.uniprot.org/uniprotkb/A8DYY2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 203, "chemical_mass": 23384.0, "gene_names": "Dmel\\CG34181;CG34181;Dmel\\CG34181;Dmel_CG34181", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JNI2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1655, "chemical_mass": 185904.0, "gene_names": "Srrm234;BcDNA:GH04236;CG7971;Dmel\\CG7971;Dmel_CG7971;SRm300;Srrm234;anon-EST:fe1A7", "protein_name": "", "disease": [ { "disease_id": "DOID:0061045", "name": "autosomal dominant intellectual developmental disorder 72", "description": "An autosomal dominant intellectual developmental disorder characterized by developmental delay, predominant speech delay, autistic or attention-deficit/hyperactivity disorder features, overfriendliness, generalized hypotonia, overweight/obesity, and dysmorphic features that has_material_basis_in heterozygous mutation in the SRRM2 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0061045", "evidence": [ { "id": "0061045", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061045" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A8JNI2", "url": "https://www.uniprot.org/uniprotkb/A8JNI2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JNI2-1", "start_pos": "916", "end_pos": "916", "site_lbl": "Thr916", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 916, "start_aa": "Thr", "end_pos": 916, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr916", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JNM1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNM1", "url": "https://www.uniprot.org/uniprotkb/A8JNM1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1717, "chemical_mass": 188938.0, "gene_names": "form3;CG14824;CG18138;CG32384;CG33556;CG8633;DIA-like;Dmel\\CG33556;Dmel_CG33556;Form3;Formin3;INF2;ah1644;form3;formin/DIA-like;form", "protein_name": "", "disease": [ { "disease_id": "DOID:0110205", "name": "Charcot-Marie-Tooth disease dominant intermediate E", "description": "A Charcot-Marie-Tooth disease intermediate type that has_material_basis_in heterozygous mutation in the INF2 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0110205", "evidence": [ { "id": "0110205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110205" } ], "weight": 0.0 }, { "disease_id": "DOID:0111130", "name": "focal segmental glomerulosclerosis 5", "description": "A focal segmental glomerulosclerosis that has_material_basis_in an autosomal dominant mutation of the INF2 gene on chromosome 14q32.33.", "url": "https://disease-ontology.org/term/DOID:0111130", "evidence": [ { "id": "0111130", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111130" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A8JNM1", "url": "https://www.uniprot.org/uniprotkb/A8JNM1" } ], "pmid": "" } ], "biological_process": [ { "name": "branch fusion, open tracheal system", "id": "GO:0035147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035147", "evidence": [ { "database": "UniProtKB", "id": "A8JNM1", "url": "https://www.uniprot.org/uniprotkb/A8JNM1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JNM1-1", "start_pos": "171", "end_pos": "171", "site_lbl": "Thr171", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JNP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 310, "chemical_mass": 34379.0, "gene_names": "I-2;CG10574;DI-2;Dm I-2;Dmel\\CG10574;Dmel_CG10574;I-2Dm;I-2PP1;I-2;I2;SET", "protein_name": "", "disease": [], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" }, { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" }, { "name": "protein phosphatase inhibitor activity", "id": "GO:0004864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004864", "evidence": [ { "database": "UniProtKB", "id": "A8JNP7", "url": "https://www.uniprot.org/uniprotkb/A8JNP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JNQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNQ7", "url": "https://www.uniprot.org/uniprotkb/A8JNQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 206, "chemical_mass": 23433.0, "gene_names": "Dmel\\CG34238;CG34238;Dmel\\CG34238;Dmel_CG34238", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JNS2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNS2", "url": "https://www.uniprot.org/uniprotkb/A8JNS2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 247, "chemical_mass": 27983.0, "gene_names": "Dmel\\CG34428;CG14116;CG34428;Dmel_CG34428", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JNS3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNS3", "url": "https://www.uniprot.org/uniprotkb/A8JNS3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 249, "chemical_mass": 27862.0, "gene_names": "Dmel\\CG34429;CG14116;CG34429;Dmel\\CG34429;Dmel_CG34429", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JPJ8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 421, "chemical_mass": 48616.0, "gene_names": "ppk31;CG31065;Dmel\\CG31065;Dmel_CG31065;Ppk31;ppk31", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A8JPJ8", "url": "https://www.uniprot.org/uniprotkb/A8JPJ8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JQT2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JQT2", "url": "https://www.uniprot.org/uniprotkb/A8JQT2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 532, "chemical_mass": 63077.0, "gene_names": "CG12584;CG12584;CG34425;CG41467;Dmel\\CG34425;Dmel_CG34425", "protein_name": "Trichohyalin", "disease": [], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A8JQT2", "url": "https://www.uniprot.org/uniprotkb/A8JQT2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JRF0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JRF0", "url": "https://www.uniprot.org/uniprotkb/A8JRF0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 266, "chemical_mass": 30212.0, "gene_names": "CG16918;CG16918;CG34437;Dmel\\CG34437;Dmel_CG34437;SPH201b;SPH201", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A8JRF0", "url": "https://www.uniprot.org/uniprotkb/A8JRF0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JUR0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 563, "chemical_mass": 62479.0, "gene_names": "Dmel\\CG8028;CG8028;Dmel\\CG8028;Dmel_CG8028;MCT", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" } ], "biological_process": [ { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" }, { "name": "monocarboxylic acid transport", "id": "GO:0015718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015718", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" }, { "name": "renal tubular secretion", "id": "GO:0097254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097254", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" } ], "molecular_function": [ { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A8JUR0", "url": "https://www.uniprot.org/uniprotkb/A8JUR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JUR3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 609, "chemical_mass": 70291.0, "gene_names": "Ir10a;10a;CG12623;CG12624;CG34143;DmelIR10a;Dmel\\CG34143;Dmel_CG34143;IR10a;Ir10a", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "A8JUR3", "url": "https://www.uniprot.org/uniprotkb/A8JUR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JUS8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JUS8", "url": "https://www.uniprot.org/uniprotkb/A8JUS8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 177, "chemical_mass": 20233.0, "gene_names": "Dmel\\CG13373;CG13373;Dmel\\CG13373;Dmel_CG13373", "protein_name": "Apoptosis regulatory protein Siva", "disease": [], "biological_process": [ { "name": "extrinsic apoptotic signaling pathway", "id": "GO:0097191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097191", "evidence": [ { "database": "UniProtKB", "id": "A8JUS8", "url": "https://www.uniprot.org/uniprotkb/A8JUS8" } ], "pmid": "" } ], "molecular_function": [ { "name": "CD27 receptor binding", "id": "GO:0005175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005175", "evidence": [ { "database": "UniProtKB", "id": "A8JUS8", "url": "https://www.uniprot.org/uniprotkb/A8JUS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7YZH0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZH0", "url": "https://www.uniprot.org/uniprotkb/B7YZH0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 145, "chemical_mass": 16296.0, "gene_names": "CG13353;CG13353;CG42287;Dmel\\CG42287;Dmel_CG42287", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7YZL9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1500, "chemical_mass": 166756.0, "gene_names": "Fak;CG10023;CT28129;DFAK;DFak56;DFak;Dfak56;Dfak;DmFAK;Dmel\\CG10023;Dmel_CG10023;FAK65D;FAK;Fak56D;Fak56;Fak;dFak;fak56D;fak56;fak;pFAK;ptk2", "protein_name": "", "disease": [ { "disease_id": "DOID:0060074", "name": "ductal carcinoma in situ", "description": "A breast carcinoma in situ that is characterized by being non-invasive, not having spread outside of the duct into the surrounding breast tissue, has_material_basis_in abnormally proliferating cells, derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:0060074", "evidence": [ { "id": "0060074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060074" } ], "weight": 0.0 }, { "disease_id": "DOID:0080365", "name": "endometrial hyperplasia", "description": "An uterine benign neoplasm that is characterized by excessive proliferation of the cells of the endometrium.", "url": "https://disease-ontology.org/term/DOID:0080365", "evidence": [ { "id": "0080365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080365" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10952", "name": "nephritis", "description": "A kidney disease that is characterized by an inflammation of the kidneys.", "url": "https://disease-ontology.org/term/DOID:10952", "evidence": [ { "id": "10952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10952" } ], "weight": 0.0 }, { "disease_id": "DOID:11713", "name": "diabetic angiopathy", "description": "A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.", "url": "https://disease-ontology.org/term/DOID:11713", "evidence": [ { "id": "11713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11713" } ], "weight": 0.0 }, { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:2893", "name": "cervix carcinoma", "description": "A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2893", "evidence": [ { "id": "2893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2893" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues.", "url": "https://disease-ontology.org/term/DOID:326", "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:4001", "name": "ovarian carcinoma", "description": "An ovarian cancer that has_material_basis_in epithelial tissue and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:4001", "evidence": [ { "id": "4001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4001" } ], "weight": 0.0 }, { "disease_id": "DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix.", "url": "https://disease-ontology.org/term/DOID:4362", "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ], "weight": 0.0 }, { "disease_id": "DOID:4676", "name": "uremia", "description": "", "url": "https://disease-ontology.org/term/DOID:4676", "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ], "weight": 0.0 }, { "disease_id": "DOID:4780", "name": "anti-basement membrane glomerulonephritis", "description": "A Goodpasture syndrome that is characterized by damage to only kidney capillaries.", "url": "https://disease-ontology.org/term/DOID:4780", "evidence": [ { "id": "4780", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4780" } ], "weight": 0.0 }, { "disease_id": "DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:5409", "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" } ], "cellular_component": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "type Ib terminal bouton", "id": "GO:0061176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061176", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "type Is terminal bouton", "id": "GO:0061177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061177", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "negative regulation of receptor recycling", "id": "GO:0001920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001920", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "signal complex assembly", "id": "GO:0007172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007172", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" }, { "name": "negative regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045886", "evidence": [ { "database": "UniProtKB", "id": "B7YZL9", "url": "https://www.uniprot.org/uniprotkb/B7YZL9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7YZM8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 957, "chemical_mass": 108178.0, "gene_names": "BBS9;BBS9;BcDNA:RH67628;CG15666;Dmel\\CG15666;Dmel_CG15666", "protein_name": "", "disease": [ { "disease_id": "DOID:0110131", "name": "Bardet-Biedl syndrome 9", "description": "A Bardet-Biedl syndrome that has_material_basis_in homozygosity or compound heterozygosity for mutations in the PTHB1 gene on chromosome 7p14.", "url": "https://disease-ontology.org/term/DOID:0110131", "evidence": [ { "id": "0110131", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110131" } ], "weight": 0.0 }, { "disease_id": "DOID:1935", "name": "Bardet-Biedl syndrome", "description": "A syndrome that results from mutations in multiple BBS genes affecting cellular cilia structure or function (ciliopathy) resulting in variable presentation and characterized principally by obesity, retinitis pigmentosa,vision loss, polydactyly, mental retardation, hypogonadism, and renal failure in some cases.", "url": "https://disease-ontology.org/term/DOID:1935", "evidence": [ { "id": "1935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1935" } ], "weight": 0.0 }, { "disease_id": "DOID:2340", "name": "craniosynostosis", "description": "A synostosis that results_in premature fusion located_in skull.", "url": "https://disease-ontology.org/term/DOID:2340", "evidence": [ { "id": "2340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2340" } ], "weight": 0.0 }, { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "pmid": "" }, { "name": "BBSome", "id": "GO:0034464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034464", "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "B7YZM8", "url": "https://www.uniprot.org/uniprotkb/B7YZM8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7YZN3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZN3", "url": "https://www.uniprot.org/uniprotkb/B7YZN3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 202, "chemical_mass": 23493.0, "gene_names": "Dmel\\CG42364;CG15675;CG42364;Dmel\\CG42364;Dmel_CG42364", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7YZQ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZQ6", "url": "https://www.uniprot.org/uniprotkb/B7YZQ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 574, "chemical_mass": 66287.0, "gene_names": "Ir60d;60d;CG13582;CG42291;DmelIR60d;Dmel\\CG42291;Dmel_CG42291;IR60d;Ir60d", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "B7YZQ6", "url": "https://www.uniprot.org/uniprotkb/B7YZQ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "B7YZQ6", "url": "https://www.uniprot.org/uniprotkb/B7YZQ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7YZQ6", "url": "https://www.uniprot.org/uniprotkb/B7YZQ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7YZU6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 109, "chemical_mass": 13240.0, "gene_names": "halo;CG7428;Dmel\\CG7428;Dmel_CG7428;halo", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" }, { "name": "lipid droplet transport along microtubule", "id": "GO:0031887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031887", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" } ], "molecular_function": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "B7YZU6", "url": "https://www.uniprot.org/uniprotkb/B7YZU6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7Z0E0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 479, "chemical_mass": 53643.0, "gene_names": "Idh;CG7176;CT22171;Dmel\\CG7176;Dmel_CG7176;ICDH;IDH (CG7176);IDH-NADP;IDH1;IDH2;IDH;Idh-NADP;Idh;cIdh;dIDH2;idh;isocitrate dehydrogenase;l(3)L3852", "protein_name": "Isocitrate dehydrogenase [NADP]", "disease": [ { "disease_id": "DOID:0050575", "name": "D-2-hydroxyglutaric aciduria", "description": "An 2-hydroxyglutaric aciduria that involves developmental delay, seizures, weak muscle tone (hypotonia), and abnormalities in the largest part of the brain (the cerebrum), which controls many important functions such as muscle movement, speech, vision, thinking, emotion, and memory.", "url": "https://disease-ontology.org/term/DOID:0050575", "evidence": [ { "id": "0050575", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050575" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.", "url": "https://disease-ontology.org/term/DOID:3068", "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell.", "url": "https://disease-ontology.org/term/DOID:3907", "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:417", "name": "autoimmune disease", "description": "An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.", "url": "https://disease-ontology.org/term/DOID:417", "evidence": [ { "id": "417", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:417" } ], "weight": 0.0 }, { "disease_id": "DOID:5016", "name": "hepatocellular clear cell carcinoma", "description": "", "url": "https://disease-ontology.org/term/DOID:5016", "evidence": [ { "id": "5016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5016" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "biological_process": [ { "name": "NADP+ metabolic process", "id": "GO:0006739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006739", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "tricarboxylic acid cycle", "id": "GO:0006099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "isocitrate metabolic process", "id": "GO:0006102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006102", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "glyoxylate cycle", "id": "GO:0006097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006097", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" } ], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "isocitrate dehydrogenase (NADP+) activity", "id": "GO:0004450", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004450", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B7Z0E0", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7Z0E3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0E3", "url": "https://www.uniprot.org/uniprotkb/B7Z0E3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 37840.0, "gene_names": "CT32600;Dmel\\CG13305;BcDNA:RE33542;CG13305;CT32600;Dmel\\CG13305;Dmel_CG13305", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7Z0K3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 455, "chemical_mass": 51193.0, "gene_names": "Dmel\\CG14866;CG14866;Dmel\\CG14866;Dmel_CG14866", "protein_name": "C-type lectin domain-containing protein", "disease": [ { "disease_id": "DOID:0050598", "name": "extrapulmonary tuberculosis", "description": "A tuberculosis that occurs at body sites other than the lung.", "url": "https://disease-ontology.org/term/DOID:0050598", "evidence": [ { "id": "0050598", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050598" } ], "weight": 0.0 }, { "disease_id": "DOID:0050827", "name": "rheumatic heart disease", "description": "A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords.", "url": "https://disease-ontology.org/term/DOID:0050827", "evidence": [ { "id": "0050827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050827" } ], "weight": 0.0 }, { "disease_id": "DOID:0080599", "name": "Coronavirus infectious disease", "description": "A viral infectious disease that has_material_basis_in Coronavirus.", "url": "https://disease-ontology.org/term/DOID:0080599", "evidence": [ { "id": "0080599", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080599" } ], "weight": 0.0 }, { "disease_id": "DOID:11650", "name": "bronchopulmonary dysplasia", "description": "A lung disease that is characterized by underdeveloped lungs in newborns that can be easily irritated or inflamed after birth resulting in damage to the alveoli of the lungs and bronchi. Most newborns who develop BPD are born more than 10 weeks before their due dates, weigh less than 2 pounds at birth, and have breathing problems.", "url": "https://disease-ontology.org/term/DOID:11650", "evidence": [ { "id": "11650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11650" } ], "weight": 0.0 }, { "disease_id": "DOID:12205", "name": "dengue disease", "description": "A viral infectious disease that results in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom severe headache, has symptom severe pain behind the eyes, has symptom joint pain, has symptom muscle and bone pain, has symptom rash, and has symptom mild bleeding.", "url": "https://disease-ontology.org/term/DOID:12205", "evidence": [ { "id": "12205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12205" } ], "weight": 0.0 }, { "disease_id": "DOID:12206", "name": "dengue hemorrhagic fever", "description": "A dengue disease that occurs when a person experiences a second infection with a heterologous Dengue virus (Orthoflavivirus denguei) serotype, which is transmitted_by Aedes mosquito bite. The infection has_symptom hemorrhagic lesions of the skin, has_symptom thrombocytopenia, has_symptom reduction in the fluid part of the blood, and has_symptom high fever. Four distinct Dengue virus serotypes have been identified.", "url": "https://disease-ontology.org/term/DOID:12206", "evidence": [ { "id": "12206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12206" } ], "weight": 0.0 }, { "disease_id": "DOID:13564", "name": "aspergillosis", "description": "An opportunistic mycosis that involves a spectrum of diseases of humans and animals caused by members of the genus Aspergillus infecting lungs, brain, kidney, heart, bone, eyes, sinuses, skin and gastrointestinal tract. It is a serious illnesses in people with a weakened immune system.", "url": "https://disease-ontology.org/term/DOID:13564", "evidence": [ { "id": "13564", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13564" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.", "url": "https://disease-ontology.org/term/DOID:399", "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:635", "name": "acquired immunodeficiency syndrome", "description": "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.", "url": "https://disease-ontology.org/term/DOID:635", "evidence": [ { "id": "635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:635" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "B7Z0K3", "url": "https://www.uniprot.org/uniprotkb/B7Z0K3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7Z0L3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 31019.0, "gene_names": "CG5240;CG31266;CG5240;Dmel\\CG31266;Dmel_CG31266;SPH146a;SPH146", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "B7Z0L3", "url": "https://www.uniprot.org/uniprotkb/B7Z0L3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7Z0S9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 243, "chemical_mass": 27841.0, "gene_names": "GstD11;BcDNA:RE72392;CG17639;DmGSTD11;Dmel\\CG17639;Dmel_CG17639;GSTD11;GstD11;cg17639;gstd11", "protein_name": "", "disease": [], "molecular_function": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "pmid": "" } ], "biological_process": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "B7Z0S9", "url": "https://www.uniprot.org/uniprotkb/B7Z0S9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "B7Z0X5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 608, "chemical_mass": 71243.0, "gene_names": "Ir7e;7e;CG15327;CG42293;DmelIR7e;Dmel\\CG42293;Dmel_CG42293;IR7e;Ir7e", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "B7Z0X5", "url": "https://www.uniprot.org/uniprotkb/B7Z0X5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E1JH12-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JH12", "url": "https://www.uniprot.org/uniprotkb/E1JH12" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 67, "chemical_mass": 7996.0, "gene_names": "Dmel\\CG42615;CG42615;Dmel\\CG42615;Dmel_CG42615;gft", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E1JHF6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHF6", "url": "https://www.uniprot.org/uniprotkb/E1JHF6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 91, "chemical_mass": 10709.0, "gene_names": "Dmel\\CG42470;CG42470;Dmel\\CG42470;Dmel_CG42470", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E1JHF9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHF9", "url": "https://www.uniprot.org/uniprotkb/E1JHF9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 215, "chemical_mass": 24011.0, "gene_names": "Dmel\\CG14932;CG14932;Dmel\\CG14932;Dmel_CG14932", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E1JHF9-1", "start_pos": "149", "end_pos": "149", "site_lbl": "Thr149", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 149, "start_aa": "Thr", "end_pos": 149, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr149", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E1JHS7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHS7", "url": "https://www.uniprot.org/uniprotkb/E1JHS7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 82, "chemical_mass": 9623.0, "gene_names": "Dmel\\CG42467;CG42467;Dmel\\CG42467;Dmel_CG42467", "protein_name": "Seminal fluid protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "E1JHS7", "url": "https://www.uniprot.org/uniprotkb/E1JHS7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E1JHT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 496, "chemical_mass": 54978.0, "gene_names": "Dmel\\CG12194;anon-EST:Posey105;CG12194;Dmel\\CG12194;Dmel_CG12194;anon-EST:Posey105", "protein_name": "Lysosomal dipeptide transporter MFSD1", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "E1JHT4", "url": "https://www.uniprot.org/uniprotkb/E1JHT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E1JJ15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJ15", "url": "https://www.uniprot.org/uniprotkb/E1JJ15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 142, "chemical_mass": 15720.0, "gene_names": "Dmel\\CG42592;CG42592;Dmel\\CG42592;Dmel_CG42592", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E1JJ89-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJ89", "url": "https://www.uniprot.org/uniprotkb/E1JJ89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 559, "chemical_mass": 62597.0, "gene_names": "CT41336;CG18249;CT41336;Dmel\\CG18249;Dmel_CG18249", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "E1JJ89-1", "start_pos": "52", "end_pos": "52", "site_lbl": "Thr52", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E1JJS0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E1JJS0", "url": "https://www.uniprot.org/uniprotkb/E1JJS0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 92, "chemical_mass": 10654.0, "gene_names": "Dmel\\CG42578;CG42578;Dmel\\CG42578;Dmel_CG42578", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E2QCN8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E2QCN8", "url": "https://www.uniprot.org/uniprotkb/E2QCN8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 123, "chemical_mass": 13519.0, "gene_names": "Dmel\\CG15870;CG15870;Dmel\\CG15870;Dmel_CG15870", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E2QCZ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E2QCZ5", "url": "https://www.uniprot.org/uniprotkb/E2QCZ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 726, "chemical_mass": 82361.0, "gene_names": "Dmel\\CG7706;CG7706;Dmel\\CG7706;Dmel_CG7706", "protein_name": "FHA domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E2QCZ5", "url": "https://www.uniprot.org/uniprotkb/E2QCZ5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "E2QD54-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "E2QD54", "url": "https://www.uniprot.org/uniprotkb/E2QD54" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 553, "chemical_mass": 62389.0, "gene_names": "natalisin;CG14842;CG14843;CG34388;Dmel\\CG34388;Dmel_CG34388;NTL;Ntl;natalisin;ntl", "protein_name": "", "disease": [], "biological_process": [ { "name": "male mating behavior", "id": "GO:0060179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060179", "evidence": [ { "database": "UniProtKB", "id": "E2QD54", "url": "https://www.uniprot.org/uniprotkb/E2QD54" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E2QD54", "url": "https://www.uniprot.org/uniprotkb/E2QD54" } ], "pmid": "" } ], "molecular_function": [ { "name": "neuropeptide activity", "id": "GO:0160041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160041", "evidence": [ { "database": "UniProtKB", "id": "E2QD54", "url": "https://www.uniprot.org/uniprotkb/E2QD54" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9MRH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRH9", "url": "https://www.uniprot.org/uniprotkb/M9MRH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 186, "chemical_mass": 20706.0, "gene_names": "Dmel\\CG42711;CG42711;Dmel\\CG42711;Dmel_CG42711", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9MRN0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRN0", "url": "https://www.uniprot.org/uniprotkb/M9MRN0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 145, "chemical_mass": 15630.0, "gene_names": "Dmel\\CG42809;CG16849;CG42809;Dmel\\CG42809;Dmel_CG42809", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9MRN0-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Thr53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9MRN7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRN7", "url": "https://www.uniprot.org/uniprotkb/M9MRN7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 167, "chemical_mass": 17879.0, "gene_names": "Dmel\\CG42846;CG42846;Dmel\\CG42846;Dmel_CG42846", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9MRP4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRP4", "url": "https://www.uniprot.org/uniprotkb/M9MRP4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 494, "chemical_mass": 56638.0, "gene_names": "Dmel\\CG13924;CG13924;Dmel\\CG13924;Dmel_CG13924", "protein_name": "Coiled-coil domain-containing protein 181", "disease": [], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "M9MRP4", "url": "https://www.uniprot.org/uniprotkb/M9MRP4" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "M9MRP4", "url": "https://www.uniprot.org/uniprotkb/M9MRP4" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "M9MRP4", "url": "https://www.uniprot.org/uniprotkb/M9MRP4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9MRP4-1", "start_pos": "330", "end_pos": "330", "site_lbl": "Thr330", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 330, "start_aa": "Thr", "end_pos": 330, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr330", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9MRQ3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRQ3", "url": "https://www.uniprot.org/uniprotkb/M9MRQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 49, "chemical_mass": 5700.0, "gene_names": "Dmel\\CG42659;CG42659;Dmel\\CG42659;Dmel_CG42659;noncoding_3557", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9MRV6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MRV6", "url": "https://www.uniprot.org/uniprotkb/M9MRV6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 79, "chemical_mass": 8820.0, "gene_names": "Dmel\\CG42718;CG42718;Dmel\\CG42718;Dmel_CG42718", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9MS52-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9MS52", "url": "https://www.uniprot.org/uniprotkb/M9MS52" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 32, "chemical_mass": 3149.0, "gene_names": "Dmel\\CG42852;CG42852;Dmel\\CG42852;Dmel_CG42852;lincRNA.585", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NCQ5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NCQ5", "url": "https://www.uniprot.org/uniprotkb/M9NCQ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 42, "chemical_mass": 4719.0, "gene_names": "Dmel\\CG43403;CG43403;Dmel\\CG43403;Dmel_CG43403", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9ND23-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9ND23", "url": "https://www.uniprot.org/uniprotkb/M9ND23" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 82, "chemical_mass": 9257.0, "gene_names": "Dmel\\CG43056;CG43056;Dmel\\CG43056;Dmel_CG43056", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NDP8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDP8", "url": "https://www.uniprot.org/uniprotkb/M9NDP8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 143, "chemical_mass": 16666.0, "gene_names": "Dmel\\CG43294;CG43294;Dmel\\CG43294;Dmel_CG43294", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "M9NDP8", "url": "https://www.uniprot.org/uniprotkb/M9NDP8" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "M9NDP8", "url": "https://www.uniprot.org/uniprotkb/M9NDP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NDQ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDQ6", "url": "https://www.uniprot.org/uniprotkb/M9NDQ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 81, "chemical_mass": 9204.0, "gene_names": "chr3L_13830834_13831226.0;CG43184;Dmel\\CG43184;Dmel_CG43184;FBgn0262813;chr3L_13830834_13831226.0", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NDU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NDU9", "url": "https://www.uniprot.org/uniprotkb/M9NDU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 70, "chemical_mass": 8203.0, "gene_names": "Dmel\\CG43156;CG43156;Dmel\\CG43156;Dmel_CG43156;lincRNA.980", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NE05-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NE05", "url": "https://www.uniprot.org/uniprotkb/M9NE05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2192, "chemical_mass": 244593.0, "gene_names": "nrm;CG32458;CG41452;CG43079;CG8779;CT16082;Dmel\\CG43079;Dmel_CG43079;nrm", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9NE05", "url": "https://www.uniprot.org/uniprotkb/M9NE05" } ], "pmid": "" } ], "biological_process": [ { "name": "synaptic target recognition", "id": "GO:0008039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008039", "evidence": [ { "database": "UniProtKB", "id": "M9NE05", "url": "https://www.uniprot.org/uniprotkb/M9NE05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NE05-1", "start_pos": "1593", "end_pos": "1593", "site_lbl": "Thr1593", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1593, "start_aa": "Thr", "end_pos": 1593, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1593", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NE05-1", "start_pos": "1814", "end_pos": "1814", "site_lbl": "Thr1814", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1814, "start_aa": "Thr", "end_pos": 1814, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1814", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9NE05-1", "start_pos": "690", "end_pos": "690", "site_lbl": "Thr690", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 690, "start_aa": "Thr", "end_pos": 690, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr690", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9NE05", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9NE05" } ] } ] }, { "uniprot_canonical_ac": "M9NE05-1", "start_pos": "692", "end_pos": "692", "site_lbl": "Thr692", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 692, "start_aa": "Thr", "end_pos": 692, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr692", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9NE05", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9NE05" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NE75-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NE75", "url": "https://www.uniprot.org/uniprotkb/M9NE75" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 60, "chemical_mass": 7059.0, "gene_names": "lincRNA.945;CG43288;Dmel\\CG43288;Dmel_CG43288;lincRNA.945", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NET3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NET3", "url": "https://www.uniprot.org/uniprotkb/M9NET3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 32, "chemical_mass": 3727.0, "gene_names": "lincRNA.182;CG43354;Dmel\\CG43354;Dmel_CG43354;lincRNA.182", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NF24-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NF24", "url": "https://www.uniprot.org/uniprotkb/M9NF24" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 628, "chemical_mass": 65322.0, "gene_names": "Dmel\\CG43332;BG:DS01523.2;CG15291;CG32972;CG43332;Dmel\\CG43332;Dmel_CG43332", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NF55-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NF55", "url": "https://www.uniprot.org/uniprotkb/M9NF55" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 174, "chemical_mass": 20933.0, "gene_names": "Dmel\\CG43075;CG43075;Dmel\\CG43075;Dmel_CG43075", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NFG6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFG6", "url": "https://www.uniprot.org/uniprotkb/M9NFG6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 72, "chemical_mass": 8040.0, "gene_names": "UQCR-6.4L;CG43206;Dmel\\CG43206;Dmel_CG43206;UQCR-6.4L;chr3L_16559870_16560394.0", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "M9NFG6", "url": "https://www.uniprot.org/uniprotkb/M9NFG6" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial electron transport, ubiquinol to cytochrome c", "id": "GO:0006122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006122", "evidence": [ { "database": "UniProtKB", "id": "M9NFG6", "url": "https://www.uniprot.org/uniprotkb/M9NFG6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0KHR3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1520, "chemical_mass": 163622.0, "gene_names": "baz;BAZ;Baz/Par-3;Baz/Par3;Bazooka;Baz;CG5055;D-Par3;D-par3;Dmel\\CG5055;Dmel_CG5055;PAR-3;PAR3;Par-3;Par3;baz;dPar-3;l(1)G0484;par-3;par3", "protein_name": "", "disease": [ { "disease_id": "DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development.", "url": "https://disease-ontology.org/term/DOID:0060037", "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ], "weight": 0.0 } ], "biological_process": [ { "name": "establishment of apical/basal cell polarity", "id": "GO:0035089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035089", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "negative regulation of filopodium assembly", "id": "GO:0051490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051490", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "branching involved in open tracheal system development", "id": "GO:0060446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060446", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "asymmetric neuroblast division", "id": "GO:0055059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055059", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "zonula adherens assembly", "id": "GO:0045186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045186", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "photoreceptor cell morphogenesis", "id": "GO:0008594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008594", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "asymmetric protein localization involved in cell fate determination", "id": "GO:0045167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045167", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "follicle cell of egg chamber-cell adhesion", "id": "GO:0007299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007299", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "Malpighian tubule development", "id": "GO:0072002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072002", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "germarium-derived oocyte fate determination", "id": "GO:0007294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007294", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "oocyte anterior/posterior axis specification", "id": "GO:0007314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007314", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "germ-band extension", "id": "GO:0007377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007377", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "oocyte microtubule cytoskeleton organization", "id": "GO:0016325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016325", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "border follicle cell delamination", "id": "GO:0030709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030709", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "axis elongation", "id": "GO:0003401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003401", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "regulation of establishment of planar polarity", "id": "GO:0090175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090175", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "apical protein localization", "id": "GO:0045176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045176", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" } ], "cellular_component": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "spot adherens junction", "id": "GO:0005914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005914", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "cytoplasmic side of apical plasma membrane", "id": "GO:0098592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098592", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "PAR polarity complex", "id": "GO:0120157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120157", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" }, { "name": "phosphatidic acid binding", "id": "GO:0070300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070300", "evidence": [ { "database": "UniProtKB", "id": "Q0KHR3", "url": "https://www.uniprot.org/uniprotkb/Q0KHR3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0E9H9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2016, "chemical_mass": 222102.0, "gene_names": "Dscam1;43Bc;CG17800;CT39257;DSCAM1;DSCAM;DScam;DmDscam;Dm_2R:13579;Dm_2R:13612;Dmel\\CG17800;Dmel_CG17800;DsCam;Dscam-hv;Dscam1;Dscam;Dsm;Neu1;dScam;dscam1;dscam;l(2)05518;l(2)43Bc;p270", "protein_name": "Cell adhesion molecule Dscam1", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080849", "name": "ocular motor apraxia, Cogan type", "description": "An eye disease that is characterized by defective or absent horizontal voluntary eye movements, and defective or absent horizontal ocular attraction movements.", "url": "https://disease-ontology.org/term/DOID:0080849", "evidence": [ { "id": "0080849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080849" } ], "weight": 0.0 }, { "disease_id": "DOID:1279", "name": "ocular motility disease", "description": "", "url": "https://disease-ontology.org/term/DOID:1279", "evidence": [ { "id": "1279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1279" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 } ], "biological_process": [ { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "central nervous system morphogenesis", "id": "GO:0021551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021551", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of touch", "id": "GO:0050976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050976", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "peripheral nervous system development", "id": "GO:0007422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007422", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axonal fasciculation", "id": "GO:0007413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007413", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "detection of molecule of bacterial origin", "id": "GO:0032490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032490", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axon extension involved in axon guidance", "id": "GO:0048846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048846", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "ventral cord development", "id": "GO:0007419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007419", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" }, { "name": "axon guidance receptor activity", "id": "GO:0008046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008046", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1022", "end_pos": "1022", "site_lbl": "Asn1022", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1022, "start_aa": "Asn", "end_pos": 1022, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1022", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1055", "end_pos": "1055", "site_lbl": "Asn1055", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1055, "start_aa": "Asn", "end_pos": 1055, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1055", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1113", "end_pos": "1113", "site_lbl": "Thr1113", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1113, "start_aa": "Thr", "end_pos": 1113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1113", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1186", "end_pos": "1186", "site_lbl": "Asn1186", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1186, "start_aa": "Asn", "end_pos": 1186, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1186", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "1219", "end_pos": "1219", "site_lbl": "Thr1219", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1219, "start_aa": "Thr", "end_pos": 1219, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1219", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "325", "end_pos": "325", "site_lbl": "Asn325", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G22768VO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "4X9F", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9F" }, { "id": "4X9F", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9F" }, { "id": "4X9G", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9G" }, { "id": "4X9G", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9G" }, { "id": "4XHQ", "database": "PDB", "url": "https://www.rcsb.org/structure/4XHQ" }, { "id": "4XHQ", "database": "PDB", "url": "https://www.rcsb.org/structure/4XHQ" }, { "id": "4X9F|B|291", "database": "", "url": "" }, { "id": "4X9G|B|291", "database": "", "url": "" }, { "id": "4X9G|A|291", "database": "", "url": "" }, { "id": "4XHQ|A|290", "database": "", "url": "" } ] }, { "glytoucan_ac": "G81315DD", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X8X|B|291", "database": "", "url": "" }, { "id": "4X8X|A|291", "database": "", "url": "" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 325, "start_aa": "Asn", "end_pos": 325, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn325", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" }, { "id": "27386517", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/27386517" }, { "id": "17721508", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/17721508" }, { "id": "4XHQ", "database": "PDB", "url": "https://www.rcsb.org/sequence/4XHQ" }, { "id": "2V5M", "database": "PDB", "url": "https://www.rcsb.org/sequence/2V5M" }, { "id": "18805093", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18805093" }, { "id": "3DMK", "database": "PDB", "url": "https://www.rcsb.org/sequence/3DMK" }, { "id": "4X83", "database": "PDB", "url": "https://www.rcsb.org/structure/4X83" }, { "id": "4X83", "database": "PDB", "url": "https://www.rcsb.org/structure/4X83" }, { "id": "4X9B", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9B" }, { "id": "4X9B", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9B" }, { "id": "4X9H", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9H" }, { "id": "4X9H", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9H" }, { "id": "4X83|D|291", "database": "", "url": "" }, { "id": "4X83|B|291", "database": "", "url": "" }, { "id": "4X83|A|291", "database": "", "url": "" }, { "id": "4X9B|A|294", "database": "", "url": "" }, { "id": "4X9B|B|294", "database": "", "url": "" }, { "id": "4X9H|B|297", "database": "", "url": "" }, { "id": "4X9H|A|297", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Thr457", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 457, "start_aa": "Thr", "end_pos": 457, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr457", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Asn492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 492, "start_aa": "Asn", "end_pos": 492, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn492", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "18805093", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18805093" }, { "id": "3DMK", "database": "PDB", "url": "https://www.rcsb.org/sequence/3DMK" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "53", "end_pos": "53", "site_lbl": "Asn53", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G22573RC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X9B", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9B" }, { "id": "4X9B", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9B" }, { "id": "4XB8", "database": "PDB", "url": "https://www.rcsb.org/structure/4XB8" }, { "id": "4XB8", "database": "PDB", "url": "https://www.rcsb.org/structure/4XB8" }, { "id": "4X8X|B|18", "database": "", "url": "" }, { "id": "4X9B|A|18", "database": "", "url": "" }, { "id": "4XB8|A|18", "database": "", "url": "" } ] }, { "glytoucan_ac": "G22768VO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "4X9F", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9F" }, { "id": "4X9F", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9F" }, { "id": "4X9G", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9G" }, { "id": "4X9G", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9G" }, { "id": "4X9F|A|18", "database": "", "url": "" }, { "id": "4X9G|A|18", "database": "", "url": "" } ] }, { "glytoucan_ac": "G81315DD", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X8X", "database": "PDB", "url": "https://www.rcsb.org/structure/4X8X" }, { "id": "4X9H", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9H" }, { "id": "4X9H", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9H" }, { "id": "4X9I", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9I" }, { "id": "4X9I", "database": "PDB", "url": "https://www.rcsb.org/structure/4X9I" }, { "id": "4X8X|A|18", "database": "", "url": "" }, { "id": "4X9H|B|18", "database": "", "url": "" }, { "id": "4X9H|A|18", "database": "", "url": "" }, { "id": "4X9I|A|18", "database": "", "url": "" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 53, "start_aa": "Asn", "end_pos": 53, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn53", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "27386517", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/27386517" }, { "id": "17721508", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/17721508" }, { "id": "18805093", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18805093" }, { "id": "4XHQ", "database": "PDB", "url": "https://www.rcsb.org/sequence/4XHQ" }, { "id": "2V5M", "database": "PDB", "url": "https://www.rcsb.org/sequence/2V5M" }, { "id": "2V5R", "database": "PDB", "url": "https://www.rcsb.org/sequence/2V5R" }, { "id": "3DMK", "database": "PDB", "url": "https://www.rcsb.org/sequence/3DMK" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" }, { "id": "4XB8", "database": "PDB", "url": "https://www.rcsb.org/structure/4XB8" }, { "id": "4XB8", "database": "PDB", "url": "https://www.rcsb.org/structure/4XB8" }, { "id": "4XB8|B|18", "database": "", "url": "" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "577", "end_pos": "577", "site_lbl": "Asn577", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 577, "start_aa": "Asn", "end_pos": 577, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn577", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "18805093", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/18805093" }, { "id": "3DMK", "database": "PDB", "url": "https://www.rcsb.org/sequence/3DMK" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "755", "end_pos": "755", "site_lbl": "Thr755", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 755, "start_aa": "Thr", "end_pos": 755, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr755", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "820", "end_pos": "820", "site_lbl": "Asn820", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 820, "start_aa": "Asn", "end_pos": 820, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn820", "evidence": [ { "id": "Q0E9H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ] } ] }, { "uniprot_canonical_ac": "Q0E9H9-1", "start_pos": "530", "end_pos": "530", "site_lbl": "Arg530", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "W", "comment": "In DscamR496W; loss of function probably due to disruption of the intramolecular binding interface between Ig-like domains 5 and 6; dorsal lobe nerve tract does not form and the medial lobe fails to extend to the midline.", "evidence": [ { "database": "UniProtKB", "id": "Q0E9H9", "url": "https://www.uniprot.org/uniprotkb/Q0E9H9" }, { "database": "PubMed", "id": "18805093", "url": "https://glygen.org/publication/PubMed/18805093" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VB15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 717, "chemical_mass": 77997.0, "gene_names": "tau;BcDNA:RE16764;CG12881;CG31057;CG31058;CG34294;CG45110;CG5606;Dmel\\CG45110;Dmel_CG45110;Tau;d-tau;dTAU;dTau;dtau;tao;tau", "protein_name": "Microtubule-associated protein", "disease": [ { "disease_id": "DOID:0050741", "name": "alcohol dependence", "description": "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.", "url": "https://disease-ontology.org/term/DOID:0050741", "evidence": [ { "id": "0050741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050741" } ], "weight": 0.0 }, { "disease_id": "DOID:0051060", "name": "frontotemporal dementia 1", "description": "A frontotemporal dementia that has_material_basis_in heterozygous mutation in the MAPT gene, which encodes microtubule-associated protein tau, on chromosome 17q21.", "url": "https://disease-ontology.org/term/DOID:0051060", "evidence": [ { "id": "0051060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051060" } ], "weight": 0.0 }, { "disease_id": "DOID:0060892", "name": "late onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.", "url": "https://disease-ontology.org/term/DOID:0060892", "evidence": [ { "id": "0060892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060892" } ], "weight": 0.0 }, { "disease_id": "DOID:0080855", "name": "Parkinsonism", "description": "A movement disorder that is characterized by disturbances of balance, gait and posture.", "url": "https://disease-ontology.org/term/DOID:0080855", "evidence": [ { "id": "0080855", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080855" } ], "weight": 0.0 }, { "disease_id": "DOID:0081292", "name": "traumatic brain injury", "description": "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.", "url": "https://disease-ontology.org/term/DOID:0081292", "evidence": [ { "id": "0081292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081292" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10914", "name": "amnestic disorder", "description": "A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information.", "url": "https://disease-ontology.org/term/DOID:10914", "evidence": [ { "id": "10914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10914" } ], "weight": 0.0 }, { "disease_id": "DOID:11870", "name": "Pick's disease", "description": "A frontotemporal dementia that is characterized by a spectrum of neuropsychiatric symptoms ranging from those that affect the patient's personality to those that cause a decline in cognitive function.", "url": "https://disease-ontology.org/term/DOID:11870", "evidence": [ { "id": "11870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11870" } ], "weight": 0.0 }, { "disease_id": "DOID:11949", "name": "Creutzfeldt-Jakob disease", "description": "", "url": "https://disease-ontology.org/term/DOID:11949", "evidence": [ { "id": "11949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11949" } ], "weight": 0.0 }, { "disease_id": "DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons.", "url": "https://disease-ontology.org/term/DOID:1289", "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ], "weight": 0.0 }, { "disease_id": "DOID:1307", "name": "dementia", "description": "A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.", "url": "https://disease-ontology.org/term/DOID:1307", "evidence": [ { "id": "1307", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1307" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 }, { "disease_id": "DOID:1561", "name": "cognitive disorder", "description": "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.", "url": "https://disease-ontology.org/term/DOID:1561", "evidence": [ { "id": "1561", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1561" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:678", "name": "progressive supranuclear palsy", "description": "A movement disease that is characterized by serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. It involves gradual deterioration and death of specific volumes of the brain.", "url": "https://disease-ontology.org/term/DOID:678", "evidence": [ { "id": "678", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:678" } ], "weight": 0.0 }, { "disease_id": "DOID:680", "name": "tauopathy", "description": "A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.", "url": "https://disease-ontology.org/term/DOID:680", "evidence": [ { "id": "680", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:680" } ], "weight": 0.0 }, { "disease_id": "DOID:8725", "name": "vascular dementia", "description": "A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.", "url": "https://disease-ontology.org/term/DOID:8725", "evidence": [ { "id": "8725", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8725" } ], "weight": 0.0 }, { "disease_id": "DOID:9255", "name": "frontotemporal dementia", "description": "A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language.", "url": "https://disease-ontology.org/term/DOID:9255", "evidence": [ { "id": "9255", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9255" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "rhabdomere morphogenesis", "id": "GO:0061541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061541", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "branching involved in open tracheal system development", "id": "GO:0060446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060446", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" }, { "name": "lumen formation, open tracheal system", "id": "GO:0035149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035149", "evidence": [ { "database": "UniProtKB", "id": "Q9VB15", "url": "https://www.uniprot.org/uniprotkb/Q9VB15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VB15-1", "start_pos": "486", "end_pos": "486", "site_lbl": "Thr486", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 486, "start_aa": "Thr", "end_pos": 486, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr486", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V435-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 890, "chemical_mass": 101860.0, "gene_names": "yuri;BG:DS05639.1;BG:DS07851.11;CG11860;CG12635;CG31732;Dmel\\CG31732;Dmel_CG31732;Yuri;yuri", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "nuclear lamina", "id": "GO:0005652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005652", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "investment cone", "id": "GO:0070865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070865", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" } ], "biological_process": [ { "name": "gravitaxis", "id": "GO:0042332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042332", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "protein localization to nuclear envelope", "id": "GO:0090435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090435", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "nuclear envelope organization", "id": "GO:0006998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006998", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "sperm individualization", "id": "GO:0007291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007291", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" }, { "name": "nuclear pore localization", "id": "GO:0051664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051664", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "Q9V435", "url": "https://www.uniprot.org/uniprotkb/Q9V435" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VHR2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1876, "chemical_mass": 206681.0, "gene_names": "CG11729;CG42286;CT32186;GS3056;MRE1;anon-EST:Posey178;43462;BcDNA:AT05815;BcDNA:GH22170;CG11718;CG11729;CG11730;CG11731;CG11733;CG31264;CG31369;CG31462;CG42285;CG42286;CG43462;CG45263;CT32186;Dmel\\CG45263;Dmel_CG45263;GH22170;GS3056;MRE1;anon-EST:Posey178", "protein_name": "Ig-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" } ], "biological_process": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q9VHR2", "url": "https://www.uniprot.org/uniprotkb/Q9VHR2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "1617", "end_pos": "1617", "site_lbl": "Thr1617", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1617, "start_aa": "Thr", "end_pos": 1617, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1617", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "1652", "end_pos": "1652", "site_lbl": "Thr1652", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1652, "start_aa": "Thr", "end_pos": 1652, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1652", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "1838", "end_pos": "1838", "site_lbl": "Thr1838", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1838, "start_aa": "Thr", "end_pos": 1838, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1838", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "326", "end_pos": "326", "site_lbl": "Ser326", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 326, "start_aa": "Ser", "end_pos": 326, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser326", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VHR2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VHR2" } ] } ] }, { "uniprot_canonical_ac": "Q9VHR2-1", "start_pos": "334", "end_pos": "334", "site_lbl": "Thr334", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 334, "start_aa": "Thr", "end_pos": 334, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr334", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VHR2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VHR2" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NFQ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 962, "chemical_mass": 96880.0, "gene_names": "Rbfox1;A2BP1;A2bp1;BcDNA:GM06073;CG14155;CG18441;CG32062;Dmel\\CG32062;Dmel_CG32062;Rbfox1;Rbox1;cg18441;dA2BP1;rbfox1", "protein_name": "", "disease": [ { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:11722", "name": "myotonic dystrophy type 1", "description": "A myotonic disease that is characterized by progressive muscle wasting and weakness affecting the distal skeletal and smooth muscles of lower legs, hands, neck, and face along with myotonia and cataracts and has_material_basis_in the autosomal dominant inheritance of the DMPK gene containing an expansion of a CTG trinucleotide repeat in the non-coding region.", "url": "https://disease-ontology.org/term/DOID:11722", "evidence": [ { "id": "11722", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11722" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3454", "name": "brain infarction", "description": "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain.", "url": "https://disease-ontology.org/term/DOID:3454", "evidence": [ { "id": "3454", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3454" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9955", "name": "hypoplastic left heart syndrome", "description": "A congenital heart disease characterized by abnormal development of the left-sided structures of the heart.", "url": "https://disease-ontology.org/term/DOID:9955", "evidence": [ { "id": "9955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9955" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "nuclear stress granule", "id": "GO:0097165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097165", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "imaginal disc-derived wing vein specification", "id": "GO:0007474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007474", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "germarium-derived oocyte differentiation", "id": "GO:0030706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030706", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "memory", "id": "GO:0007613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007613", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "Cajal body organization", "id": "GO:0030576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030576", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "cellular response to chemical stress", "id": "GO:0062197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062197", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "M9NFQ7", "url": "https://www.uniprot.org/uniprotkb/M9NFQ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NFQ7-1", "start_pos": "284", "end_pos": "284", "site_lbl": "Thr284", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 284, "start_aa": "Thr", "end_pos": 284, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr284", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KVY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2777, "chemical_mass": 297664.0, "gene_names": "PsGEF;CG14045;CG14047;CG43947;DmPsGEF;Dmel\\CG43947;Dmel_CG43947;EG:BACH48C10.4;EG:BACH7M4.1;EG:BACH7M4.2;FBgn0264598;PsGEF;PsGef;null;psGEF", "protein_name": "", "disease": [], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of Rac protein signal transduction", "id": "GO:0035022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035022", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "positive regulation of ruffle assembly", "id": "GO:1900029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900029", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7KVY9", "url": "https://www.uniprot.org/uniprotkb/Q7KVY9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KVY9-1", "start_pos": "1756", "end_pos": "1756", "site_lbl": "Thr1756", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1756, "start_aa": "Thr", "end_pos": 1756, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1756", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHU0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2263, "chemical_mass": 243755.0, "gene_names": "CG12432;CG8557;CG12432;CG43658;CG8557;Dmel\\CG43658;Dmel_CG43658", "protein_name": "DH domain-containing protein", "disease": [ { "disease_id": "DOID:0050668", "name": "alcohol-related birth defects", "description": "A fetal alcohol spectrum disorder that results in damage to organs, bones, or muscles due to prenatal alcohol exposure.", "url": "https://disease-ontology.org/term/DOID:0050668", "evidence": [ { "id": "0050668", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050668" } ], "weight": 0.0 }, { "disease_id": "DOID:0050933", "name": "ovarian serous carcinoma", "description": "An ovarian carcinoma that has_material_basis_in the lining of the ovary and produces a serum-like fluid.", "url": "https://disease-ontology.org/term/DOID:0050933", "evidence": [ { "id": "0050933", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050933" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:6212", "name": "ovarian endometrial cancer", "description": "An ovary epithelial cancer that has_material_basis_in the endometrium and is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:6212", "evidence": [ { "id": "6212", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6212" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "M9PHU0", "url": "https://www.uniprot.org/uniprotkb/M9PHU0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PHU0-1", "start_pos": "369", "end_pos": "369", "site_lbl": "Thr369", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 369, "start_aa": "Thr", "end_pos": 369, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr369", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KUQ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2147, "chemical_mass": 245500.0, "gene_names": "Lmpt;BcDNA:RE37250;CG11914;CG11915;CG11916;CG32171;CG33256;CG42679;CG9959;Dmel\\CG42679;Dmel_CG42679;Lmpt;lmpt", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" }, { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" } ], "biological_process": [ { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "Q7KUQ6", "url": "https://www.uniprot.org/uniprotkb/Q7KUQ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KUQ6-1", "start_pos": "1114", "end_pos": "1114", "site_lbl": "Thr1114", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1114, "start_aa": "Thr", "end_pos": 1114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1114", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PFZ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 773, "chemical_mass": 78192.0, "gene_names": "Nopp140;CG7421;DmNopp140;Dmel\\CG7421;Dmel_CG7421;NCL;Nopp- 140;Nopp140;nopp140", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "pmid": "" } ], "biological_process": [ { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "pmid": "" }, { "name": "rRNA 2'-O-methylation", "id": "GO:0000451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000451", "evidence": [ { "database": "UniProtKB", "id": "M9PFZ1", "url": "https://www.uniprot.org/uniprotkb/M9PFZ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "339", "end_pos": "339", "site_lbl": "Thr339", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 339, "start_aa": "Thr", "end_pos": 339, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr339", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "371", "end_pos": "371", "site_lbl": "Thr371", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 371, "start_aa": "Thr", "end_pos": 371, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr371", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "403", "end_pos": "403", "site_lbl": "Thr403", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 403, "start_aa": "Thr", "end_pos": 403, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr403", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "408", "end_pos": "408", "site_lbl": "Thr408", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 408, "start_aa": "Thr", "end_pos": 408, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr408", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFZ1-1", "start_pos": "436", "end_pos": "436", "site_lbl": "Thr436", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 436, "start_aa": "Thr", "end_pos": 436, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr436", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCE3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCE3", "url": "https://www.uniprot.org/uniprotkb/M9PCE3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1901, "chemical_mass": 213595.0, "gene_names": "Dmel\\CG18304;CG13774;CG18304;Dmel\\CG18304;Dmel_CG18304", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PB01-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2397, "chemical_mass": 262843.0, "gene_names": "Wdr62;CG7337;Dmel\\CG7337;Dmel_CG7337;Q0E8U7_DROME;WDR62;Wdr62;wdr62", "protein_name": "", "disease": [ { "disease_id": "DOID:0070293", "name": "primary autosomal recessive microcephaly 2 with or without cortical malformations", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the WDR62 gene on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0070293", "evidence": [ { "id": "0070293", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070293" } ], "weight": 0.0 }, { "disease_id": "DOID:0070296", "name": "autosomal recessive primary microcephaly", "description": "A primary microcephaly characterized by microcephaly present at birth, where the brain is small but has normal architecture, and nonprogressive mental retardation that has_material_basis_in an autosomal recessive mutation.", "url": "https://disease-ontology.org/term/DOID:0070296", "evidence": [ { "id": "0070296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070296" } ], "weight": 0.0 }, { "disease_id": "DOID:0080918", "name": "polymicrogyria", "description": "A brain disease that is characterized by malformation of the developing brain characterized by abnormal cortical lamination and an unusual folding pattern of the cerebral cortex such that all or part of the brain surface is taken up by an excessive number of small folds (gyri).", "url": "https://disease-ontology.org/term/DOID:0080918", "evidence": [ { "id": "0080918", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080918" } ], "weight": 0.0 }, { "disease_id": "DOID:0111127", "name": "nephronophthisis 20", "description": "A nephronophthisis that has_material_basis_in homozygous or compound heterozygous mutation in the MAPKBP1 gene on chromosome 15q15.", "url": "https://disease-ontology.org/term/DOID:0111127", "evidence": [ { "id": "0111127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111127" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" }, { "name": "interphase microtubule organizing center", "id": "GO:0031021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031021", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" }, { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "M9PB01", "url": "https://www.uniprot.org/uniprotkb/M9PB01" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PB01-1", "start_pos": "223", "end_pos": "223", "site_lbl": "Thr223", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 223, "start_aa": "Thr", "end_pos": 223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr223", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VIM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIM4", "url": "https://www.uniprot.org/uniprotkb/Q9VIM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 117, "chemical_mass": 13869.0, "gene_names": "38C.48;Dmel\\CG15130;38C.48;CG15130;Dmel\\CG15130;Dmel_CG15130", "protein_name": "Transmembrane inner ear expressed protein", "disease": [ { "disease_id": "DOID:0110512", "name": "autosomal recessive nonsyndromic deafness 6", "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with severe to profound, stable hearing loss and has_material_basis_in mutation in the TMIE gene on chromosome 3p21.", "url": "https://disease-ontology.org/term/DOID:0110512", "evidence": [ { "id": "0110512", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110512" } ], "weight": 0.0 }, { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V9N3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 425, "chemical_mass": 48041.0, "gene_names": "Dmel\\CG3635;CG3635;Dmel\\CG3635;Dmel_CG3635", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 } ], "biological_process": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "pmid": "" } ], "molecular_function": [ { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "pmid": "" }, { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9V9N3", "url": "https://www.uniprot.org/uniprotkb/Q9V9N3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9V9N3-1", "start_pos": "343", "end_pos": "343", "site_lbl": "Thr343", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 343, "start_aa": "Thr", "end_pos": 343, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr343", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PC26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PC26", "url": "https://www.uniprot.org/uniprotkb/M9PC26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2021, "chemical_mass": 225996.0, "gene_names": "CG10020;CG31772;CG31959;CG10020;CG31772;CG31959;CG43707;Dmel\\CG43707;Dmel_CG43707", "protein_name": "", "disease": [], "cellular_component": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "M9PC26", "url": "https://www.uniprot.org/uniprotkb/M9PC26" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PC26-1", "start_pos": "829", "end_pos": "829", "site_lbl": "Thr829", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 829, "start_aa": "Thr", "end_pos": 829, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr829", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PC26-1", "start_pos": "947", "end_pos": "947", "site_lbl": "Thr947", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 947, "start_aa": "Thr", "end_pos": 947, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr947", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PC26-1", "start_pos": "966", "end_pos": "966", "site_lbl": "Thr966", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 966, "start_aa": "Thr", "end_pos": 966, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr966", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IPJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 711, "chemical_mass": 78469.0, "gene_names": "Nhe3;CG11328;DmNHE3;Dmel\\CG11328;Dmel_CG11328;NHE3;NHE;Nhe3;nhe3", "protein_name": "Sodium/hydrogen exchanger", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0060825", "name": "Christianson syndrome", "description": "A syndromic X-linked intellectual disability characterized by microcephaly, impaired ocular movements, progressive severe global developmental delay, developmental regression, hypotonia, abnormal movements, and early-onset seizures of variable types that has_material_basis_in mutation in hemizygous mutation in the SLC9A6 gene on chromosome Xq26.", "url": "https://disease-ontology.org/term/DOID:0060825", "evidence": [ { "id": "0060825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060825" } ], "weight": 0.0 }, { "disease_id": "DOID:0111844", "name": "X-linked intellectual developmental disorder 108", "description": "A syndromic X-linked intellectual disability characterized by global developmental delay, delayed walking, and poor speech acquisition that has_material_basis_in hemizygous mutation in the SLC9A7 gene on chromosome Xp11.3.", "url": "https://disease-ontology.org/term/DOID:0111844", "evidence": [ { "id": "0111844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111844" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of pH", "id": "GO:0006885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006885", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" }, { "name": "sodium ion import across plasma membrane", "id": "GO:0098719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", "evidence": [ { "database": "UniProtKB", "id": "Q8IPJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IPJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCG3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2298, "chemical_mass": 260629.0, "gene_names": "Ziz;BcDNA:RH71439;CG15819;CG42533;CG6630;Dm ziz;Dmel\\CG42533;Dmel_CG42533;Ziz", "protein_name": "", "disease": [], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "pmid": "" }, { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "M9PCG3", "url": "https://www.uniprot.org/uniprotkb/M9PCG3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PCG3-1", "start_pos": "861", "end_pos": "861", "site_lbl": "Thr861", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 861, "start_aa": "Thr", "end_pos": 861, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr861", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHU7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1248, "chemical_mass": 135157.0, "gene_names": "CG43113;CG5741;CG43113;CG43783;CG5741;Dmel\\CG43783;Dmel_CG43783", "protein_name": "SMP-LTD domain-containing protein", "disease": [], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "M9PHU7", "url": "https://www.uniprot.org/uniprotkb/M9PHU7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PHU7-1", "start_pos": "172", "end_pos": "172", "site_lbl": "Thr172", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 172, "start_aa": "Thr", "end_pos": 172, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PF47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 760, "chemical_mass": 82239.0, "gene_names": "FoxK;CG11799;DmLD16137;DmMNF;Dmel\\CG11799;Dmel_CG11799;FoxK;MNF;Mnf;dFoxK;fd68A;fork head transcription factor long isoform;fork head transcription factor short isoform", "protein_name": "", "disease": [], "biological_process": [ { "name": "visceral mesoderm-endoderm interaction involved in midgut development", "id": "GO:0007495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007495", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "midgut development", "id": "GO:0007494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007494", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PF47", "url": "https://www.uniprot.org/uniprotkb/M9PF47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCD4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1214, "chemical_mass": 136092.0, "gene_names": "Liprin-alpha;CG11199;DLiprin-alpha;DLiprin;Dliprin-alpha;Dmel\\CG11199;Dmel_CG11199;LIP.1;LIP1;LIP;LPR;Liprin-alpha;Liprin;lip-alpha;liprin-alpha;liprin;lpr;oos", "protein_name": "", "disease": [], "biological_process": [ { "name": "presynapse assembly", "id": "GO:0099054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099054", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synaptic assembly at neuromuscular junction", "id": "GO:0051124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051124", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "axon extension", "id": "GO:0048675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "regulation of axon extension involved in axon guidance", "id": "GO:0048841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048841", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "retinal ganglion cell axon guidance", "id": "GO:0031290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031290", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "photoreceptor cell morphogenesis", "id": "GO:0008594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008594", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "axon target recognition", "id": "GO:0007412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007412", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "R7 cell development", "id": "GO:0045467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045467", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synaptic vesicle localization", "id": "GO:0097479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097479", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "presynaptic active zone organization", "id": "GO:1990709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990709", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" } ], "cellular_component": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" }, { "name": "presynaptic cytosol", "id": "GO:0099523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099523", "evidence": [ { "database": "UniProtKB", "id": "M9PCD4", "url": "https://www.uniprot.org/uniprotkb/M9PCD4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VKI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2189, "chemical_mass": 251504.0, "gene_names": "cmet;CENP-E meta;CENP-E;CENP-META;CENP-Meta;CENPE;CENPmeta;CG6392;Cenp-E;Cenp-M;Cenp-meta;Cenp_E;Cmet;DmCmeta;DmCmet;Dmel\\CG6392;Dmel_CG6392;KIF 10;KIF10;cmet;l(2)04431", "protein_name": "", "disease": [ { "disease_id": "DOID:0070283", "name": "primary autosomal recessive microcephaly 13", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the CENPE gene on chromosome 4q24.", "url": "https://disease-ontology.org/term/DOID:0070283", "evidence": [ { "id": "0070283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070283" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q9VKI0", "url": "https://www.uniprot.org/uniprotkb/Q9VKI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VIM1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIM1", "url": "https://www.uniprot.org/uniprotkb/Q9VIM1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 714, "chemical_mass": 77801.0, "gene_names": "CG11016;CG11017;Dmel\\CG31688;38C.49;38C.52;CG11016;CG11017;CG11019;CG18597;CG31688-PA;CG31688;Dmel\\CG31688;Dmel_CG31688", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PER3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PER3", "url": "https://www.uniprot.org/uniprotkb/M9PER3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 599, "chemical_mass": 68741.0, "gene_names": "Dmel\\CG13293;CG13293;Dmel\\CG13293;Dmel_CG13293", "protein_name": "Protein SCAI", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PER3", "url": "https://www.uniprot.org/uniprotkb/M9PER3" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "M9PER3", "url": "https://www.uniprot.org/uniprotkb/M9PER3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PER3", "url": "https://www.uniprot.org/uniprotkb/M9PER3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PF57-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1385, "chemical_mass": 154599.0, "gene_names": "BcDNA:RH19933;CG14172;CG32049;CG32051;CG8154;CG8163;BcDNA:RE55923;BcDNA:RH19933;CG14172;CG32049;CG32050;CG32051;CG33205;CG43897;CG8154;CG8163;Dmel\\CG43897;Dmel_CG43897", "protein_name": "Zasp-like motif domain-containing protein", "disease": [], "biological_process": [ { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "M9PF57", "url": "https://www.uniprot.org/uniprotkb/M9PF57" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PF57-1", "start_pos": "353", "end_pos": "353", "site_lbl": "Thr353", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 353, "start_aa": "Thr", "end_pos": 353, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr353", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PF57-1", "start_pos": "471", "end_pos": "471", "site_lbl": "Thr471", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 471, "start_aa": "Thr", "end_pos": 471, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr471", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PF57-1", "start_pos": "938", "end_pos": "938", "site_lbl": "Thr938", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 938, "start_aa": "Thr", "end_pos": 938, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr938", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PER1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 447, "chemical_mass": 47924.0, "gene_names": "Atg18a;ATG18.1;ATG18a;ATG18;Atg18A;Atg18a;Atg18;CG7986;Dmel\\CG7986;Dmel_CG7986;atg18.1;atg18a;atg18", "protein_name": "", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "regulation of defense response to virus", "id": "GO:0050688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050688", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "glycophagy", "id": "GO:0061723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061723", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "larval midgut histolysis", "id": "GO:0035069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035069", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "larval midgut cell programmed cell death", "id": "GO:0035096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035096", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "T-tubule organization", "id": "GO:0033292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033292", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "nucleophagy", "id": "GO:0044804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044804", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "pexophagy", "id": "GO:0000425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000425", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate binding", "id": "GO:0080025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080025", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "M9PER1", "url": "https://www.uniprot.org/uniprotkb/M9PER1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PGC0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 368, "chemical_mass": 42260.0, "gene_names": "M6;CG7540;Dmel\\CG7540;Dmel_CG7540;M6;dM6a;m6", "protein_name": "", "disease": [ { "disease_id": "DOID:0110773", "name": "hereditary spastic paraplegia 2", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the PLP1 gene on chromosome Xq22.2.", "url": "https://disease-ontology.org/term/DOID:0110773", "evidence": [ { "id": "0110773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110773" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:3210", "name": "Pelizaeus-Merzbacher disease", "description": "A hypomyelinating leukodystrophy characterized by impaired myelin formation, nystagmus, spastic quadriplegia, ataxia, and developmental delay that has_material_basis_in mutation in the PLP1 gene on chromosome Xq22.", "url": "https://disease-ontology.org/term/DOID:3210", "evidence": [ { "id": "3210", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3210" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "tricellular tight junction", "id": "GO:0061689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061689", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" } ], "biological_process": [ { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "positive phototaxis", "id": "GO:0046956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046956", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "tricellular tight junction assembly", "id": "GO:1904274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904274", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" }, { "name": "maintenance of epithelial integrity, open tracheal system", "id": "GO:0035160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035160", "evidence": [ { "database": "UniProtKB", "id": "M9PGC0", "url": "https://www.uniprot.org/uniprotkb/M9PGC0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 887, "chemical_mass": 95553.0, "gene_names": "Hk;CG17779;CG2287;CG32688;CG34319;CG43388;Dm_X:51771;Dmel\\CG43388;Dmel_CG43388;HK;Hk;hk;lincRNA.975", "protein_name": "", "disease": [ { "disease_id": "DOID:0060410", "name": "chromosome 1p36 deletion syndrome", "description": "A chromosomal deletion syndrome that has_material_basis_in by deletion of the chromosome 1p36 region and is characterized by severe intellectual disability, a small head, deep-set eyes with straight eyebrows, midface hypoplasia, a broad, flat nose, a pointed chin and low-set ears.", "url": "https://disease-ontology.org/term/DOID:0060410", "evidence": [ { "id": "0060410", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060410" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" } ], "molecular_function": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "alcohol dehydrogenase (NADP+) activity", "id": "GO:0008106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008106", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "potassium channel activator activity", "id": "GO:0099104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099104", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of circadian sleep/wake cycle, sleep", "id": "GO:0045938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045938", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "circadian sleep/wake cycle, sleep", "id": "GO:0050802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050802", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" }, { "name": "regulation of potassium ion transmembrane transport", "id": "GO:1901379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901379", "evidence": [ { "database": "UniProtKB", "id": "M9PHI0", "url": "https://www.uniprot.org/uniprotkb/M9PHI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PHI0-1", "start_pos": "200", "end_pos": "200", "site_lbl": "Thr200", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 200, "start_aa": "Thr", "end_pos": 200, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr200", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PBJ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3664, "chemical_mass": 412844.0, "gene_names": "zormin;BcDNA:GH09541;CG11850;CG11952;CG11953;CG1282;CG32307;CG32309;CG32310;CG32311;CG33484;CG5699;CT36990;Dmel\\CG33484;Dmel_CG33484;Zormin;zormin", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "M9PBJ1", "url": "https://www.uniprot.org/uniprotkb/M9PBJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "2215", "end_pos": "2215", "site_lbl": "Thr2215", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2215, "start_aa": "Thr", "end_pos": 2215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2215", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "2438", "end_pos": "2438", "site_lbl": "Thr2438", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 2438, "start_aa": "Thr", "end_pos": 2438, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2438", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PBJ1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PBJ1" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "2641", "end_pos": "2641", "site_lbl": "Thr2641", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2641, "start_aa": "Thr", "end_pos": 2641, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2641", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "3012", "end_pos": "3012", "site_lbl": "Thr3012", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3012, "start_aa": "Thr", "end_pos": 3012, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3012", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "3014", "end_pos": "3014", "site_lbl": "Thr3014", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3014, "start_aa": "Thr", "end_pos": 3014, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3014", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "3195", "end_pos": "3195", "site_lbl": "Thr3195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3195, "start_aa": "Thr", "end_pos": 3195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3195", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PBJ1-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPI3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1998, "chemical_mass": 221393.0, "gene_names": "Cda5;BcDNA:RH43162;CG2761;CG2776;CG31973;Cda5;DmCDA5;Dmel\\CG31973;Dmel_CG31973", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" }, { "name": "chitin deacetylase activity", "id": "GO:0004099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004099", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" }, { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds", "id": "GO:0016810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016810", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI3", "url": "https://www.uniprot.org/uniprotkb/Q9VPI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VPI3-1", "start_pos": "1470", "end_pos": "1470", "site_lbl": "Thr1470", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1470, "start_aa": "Thr", "end_pos": 1470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1470", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VPI3-1", "start_pos": "337", "end_pos": "337", "site_lbl": "Thr337", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 337, "start_aa": "Thr", "end_pos": 337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PG15-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1062, "chemical_mass": 116711.0, "gene_names": "SPoCk;2;ATP2C1/2;ATP2CD1;CG14449;CG32451;CG7651;Dmel\\CG32451;Dmel_CG32451;SPoCK;SPoCk;anon-WO0118547.249;sPoCk", "protein_name": "P-type Ca(2+) transporter", "disease": [ { "disease_id": "DOID:0050429", "name": "Hailey-Hailey disease", "description": "A pemphigus that is characterized by recurring blistering most commonly occurring in the folds of the skin, particularly the groin and axillary regions, and has_material_basis_in mutations in the ATP2C1 gene that result in loss of adhesion within the skin. Other sites of the body, such as the neck, perianal, and submammary regions, may likewise be affected.", "url": "https://disease-ontology.org/term/DOID:0050429", "evidence": [ { "id": "0050429", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050429" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "P-type calcium transporter activity", "id": "GO:0005388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005388", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "P-type manganese transporter activity", "id": "GO:0140613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140613", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "peroxisomal membrane transport", "id": "GO:0015919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015919", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "calcium ion transmembrane transport", "id": "GO:0070588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "manganese ion transport", "id": "GO:0006828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006828", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "calcium ion transport from cytosol to endoplasmic reticulum", "id": "GO:1903515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903515", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "Golgi calcium ion transmembrane transport", "id": "GO:0061856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061856", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" } ], "cellular_component": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "M9PG15", "url": "https://www.uniprot.org/uniprotkb/M9PG15" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PG15-1", "start_pos": "685", "end_pos": "685", "site_lbl": "Thr685", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 685, "start_aa": "Thr", "end_pos": 685, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr685", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PFY3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFY3", "url": "https://www.uniprot.org/uniprotkb/M9PFY3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1549, "chemical_mass": 166718.0, "gene_names": "CG33291;CG11250;CG33291;CG33292;CG43980;Dmel\\CG43980;Dmel_CG43980", "protein_name": "BTB domain-containing protein", "disease": [], "molecular_function": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "M9PFY3", "url": "https://www.uniprot.org/uniprotkb/M9PFY3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PFY3-1", "start_pos": "1196", "end_pos": "1196", "site_lbl": "Thr1196", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1196, "start_aa": "Thr", "end_pos": 1196, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1196", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFY3-1", "start_pos": "321", "end_pos": "321", "site_lbl": "Thr321", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 321, "start_aa": "Thr", "end_pos": 321, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr321", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFY3-1", "start_pos": "422", "end_pos": "422", "site_lbl": "Thr422", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 422, "start_aa": "Thr", "end_pos": 422, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr422", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PFY3-1", "start_pos": "80", "end_pos": "80", "site_lbl": "Thr80", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 80, "start_aa": "Thr", "end_pos": 80, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr80", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQ43-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ43", "url": "https://www.uniprot.org/uniprotkb/Q8IQ43" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 764, "chemical_mass": 87067.0, "gene_names": "Dmel\\CG11227;CG11227;Dmel\\CG11227;Dmel_CG11227", "protein_name": "DUF4729 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PI51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 447, "chemical_mass": 48891.0, "gene_names": "Dmel\\CG10089;CG10089;Dmel\\CG10089;Dmel_CG10089", "protein_name": "Dual specificity protein phosphatase 15", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "M9PI51", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PC61-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PC61", "url": "https://www.uniprot.org/uniprotkb/M9PC61" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 606, "chemical_mass": 69811.0, "gene_names": "Dmel\\CG31664;CG15622;CG31664;Dmel_CG31664", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQ73-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1107, "chemical_mass": 121987.0, "gene_names": "corn;CG32386;CG32390;CG42278;CG8621;Corn;Dmel\\CG42278;Dmel_CG42278;corn", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of exocytosis", "id": "GO:0045921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045921", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ73", "url": "https://www.uniprot.org/uniprotkb/Q8IQ73" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQ73-1", "start_pos": "158", "end_pos": "158", "site_lbl": "Thr158", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 158, "start_aa": "Thr", "end_pos": 158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr158", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IQ73-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDR5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDR5", "url": "https://www.uniprot.org/uniprotkb/Q9VDR5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 86, "chemical_mass": 9903.0, "gene_names": "Dmel\\CG4783;GH26202;CG4783;Dmel\\CG4783;Dmel_CG4783;GH26202", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VAV5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 5080, "chemical_mass": 581089.0, "gene_names": "Dhc98D;CG1842;DHC6;DHC;Dhc98D;Dhc;Dmel\\CG1842;Dmel_CG1842;dhc", "protein_name": "", "disease": [ { "disease_id": "DOID:0060250", "name": "idiopathic scoliosis", "description": "A scoliosis with no known cause.", "url": "https://disease-ontology.org/term/DOID:0060250", "evidence": [ { "id": "0060250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060250" } ], "weight": 0.0 }, { "disease_id": "DOID:0111910", "name": "spermatogenic failure", "description": "A male infertility characterized by disruption of the process of sperm development from diploid cells into mature haploid spermatozoa.", "url": "https://disease-ontology.org/term/DOID:0111910", "evidence": [ { "id": "0111910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111910" } ], "weight": 0.0 }, { "disease_id": "DOID:0112336", "name": "spermatogenic failure 56", "description": "A spermatogenic failure characterized by male infertility due to multiple morphologic abnormalities of the flagella with severely reduced sperm motility that has_material_basis_in homozygous or compound heterozygous mutation in the DNAH10 gene on chromosome 12q24.31.", "url": "https://disease-ontology.org/term/DOID:0112336", "evidence": [ { "id": "0112336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112336" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "inner dynein arm assembly", "id": "GO:0036159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036159", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "inner dynein arm", "id": "GO:0036156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036156", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV5", "url": "https://www.uniprot.org/uniprotkb/Q9VAV5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VAV5-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VAV5-1", "start_pos": "2659", "end_pos": "2659", "site_lbl": "Thr2659", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2659, "start_aa": "Thr", "end_pos": 2659, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2659", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VAV5-1", "start_pos": "3205", "end_pos": "3205", "site_lbl": "Thr3205", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3205, "start_aa": "Thr", "end_pos": 3205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3205", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VMN3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 438, "chemical_mass": 50410.0, "gene_names": "Cdkl;AC018104;CG7236/Cdk1l;CG7236;Cdk1l;Dmel\\CG7236;Dmel_CG7236;KKIALRE", "protein_name": "Cyclin-dependent kinase-like 2", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN3", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KTA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 626, "chemical_mass": 68800.0, "gene_names": "Gpo3;BG:DS08249.2;CG7311;Dmel\\CG7311;Dmel_CG7311;GPO-3;GPO;Gpo3;Gpo;alpha-GPO;gpo-3", "protein_name": "Glycerol-3-phosphate dehydrogenase", "disease": [], "molecular_function": [ { "name": "glycerol-3-phosphate dehydrogenase (quinone) activity", "id": "GO:0004368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004368", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" } ], "biological_process": [ { "name": "glycerol-3-phosphate metabolic process", "id": "GO:0006072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006072", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" }, { "name": "glycerol-3-phosphate shuttle", "id": "GO:0006127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006127", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q7KTA9", "url": "https://www.uniprot.org/uniprotkb/Q7KTA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KTA9-1", "start_pos": "313", "end_pos": "313", "site_lbl": "Thr313", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VJ99-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJ99", "url": "https://www.uniprot.org/uniprotkb/Q9VJ99" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 258, "chemical_mass": 29717.0, "gene_names": "CT35055;Dmel\\CG15155;CG15155;CT35055;Dmel\\CG15155;Dmel_CG15155", "protein_name": "GCN5-related N-acetyltransferase Rv2170-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ99", "url": "https://www.uniprot.org/uniprotkb/Q9VJ99" } ], "pmid": "" }, { "name": "glycine N-acyltransferase activity", "id": "GO:0047961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047961", "evidence": [ { "database": "UniProtKB", "id": "Q9VJ99", "url": "https://www.uniprot.org/uniprotkb/Q9VJ99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PE53-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1069, "chemical_mass": 116706.0, "gene_names": "mwh;BP1018;CG13913;CG34022;CG43772;Dmel\\CG43772;Dmel_CG43772;Mwh;mwh", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "regulation of cell morphogenesis", "id": "GO:0022604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022604", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "establishment of planar polarity", "id": "GO:0001736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001736", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "imaginal disc-derived wing hair site selection", "id": "GO:0035320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035320", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "imaginal disc-derived wing hair organization", "id": "GO:0035317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035317", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PE53", "url": "https://www.uniprot.org/uniprotkb/M9PE53" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PE53-1", "start_pos": "949", "end_pos": "949", "site_lbl": "Thr949", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 949, "start_aa": "Thr", "end_pos": 949, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr949", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VMY0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 319, "chemical_mass": 36069.0, "gene_names": "jet;CG8873;Dmel\\CG8873;Dmel_CG8873;FBXL15;JETLAG;JET;Jet;jet", "protein_name": "", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "pmid": "" } ], "biological_process": [ { "name": "locomotor rhythm", "id": "GO:0045475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045475", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q9VMY0", "url": "https://www.uniprot.org/uniprotkb/Q9VMY0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q86B99-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q86B99", "url": "https://www.uniprot.org/uniprotkb/Q86B99" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 893, "chemical_mass": 98063.0, "gene_names": "CG18546;CG14732;CG18546;CG31211;Dmel\\CG31211;Dmel_CG31211;anon-WO03070958.3;cDNA", "protein_name": "Arginine/serine-rich protein PNISR", "disease": [], "cellular_component": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q86B99", "url": "https://www.uniprot.org/uniprotkb/Q86B99" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "Q86B99", "url": "https://www.uniprot.org/uniprotkb/Q86B99" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q86B99", "url": "https://www.uniprot.org/uniprotkb/Q86B99" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q59E43-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 140, "chemical_mass": 15273.0, "gene_names": "Dmel\\CG32576;anon-AE003501.1;BcDNA:RE29988;CG32576;Dmel\\CG32576;Dmel_CG32576;NEST:bs01h05;anon-AE003501.1", "protein_name": "Vesicle transport protein GOT1B", "disease": [], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" } ], "biological_process": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q59E43", "url": "https://www.uniprot.org/uniprotkb/Q59E43" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1220, "chemical_mass": 135807.0, "gene_names": "stumps;0837/10;10;CG18485;CG31317;CG3375;C;DOF;Dmel\\CG31317;Dmel_CG31317;Dof/stumps/heartbroken;Dof;Hbr/Dof;Hbr;P1740;Stumps;anon-EST:CL47;anon-estC;dof/hbr/sms;dof/hbr;dof1;dof;gene C;hbr;heartbroken/dof;heartbroken;i21;i28;l(3)09904;l(3)S083710;sms;stumps/dof;stumps", "protein_name": "", "disease": [ { "disease_id": "DOID:1580", "name": "diffuse scleroderma", "description": "", "url": "https://disease-ontology.org/term/DOID:1580", "evidence": [ { "id": "1580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1580" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:7188", "name": "autoimmune thyroiditis", "description": "An autoimmune disease of endocrine system that involves inflammation located_in thyroid gland caused by the immune system reacting against its own tissues.", "url": "https://disease-ontology.org/term/DOID:7188", "evidence": [ { "id": "7188", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7188" } ], "weight": 0.0 }, { "disease_id": "DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales.", "url": "https://disease-ontology.org/term/DOID:8893", "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ], "weight": 0.0 }, { "disease_id": "DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.", "url": "https://disease-ontology.org/term/DOID:9074", "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "biological_process": [ { "name": "glial cell development", "id": "GO:0021782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021782", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "mesodermal cell migration", "id": "GO:0008078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008078", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "mesodermal cell fate commitment", "id": "GO:0001710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001710", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008543", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "tracheal outgrowth, open tracheal system", "id": "GO:0007426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007426", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "epithelial cell migration, open tracheal system", "id": "GO:0007427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007427", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "epithelial cell fate determination, open tracheal system", "id": "GO:0007425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007425", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane receptor protein tyrosine kinase adaptor activity", "id": "GO:0005068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005068", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor binding", "id": "GO:0005104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005104", "evidence": [ { "database": "UniProtKB", "id": "Q9VFI0", "url": "https://www.uniprot.org/uniprotkb/Q9VFI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VFI0-1", "start_pos": "1057", "end_pos": "1057", "site_lbl": "Thr1057", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1057, "start_aa": "Thr", "end_pos": 1057, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1057", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VFI0-1", "start_pos": "1067", "end_pos": "1067", "site_lbl": "Thr1067", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1067, "start_aa": "Thr", "end_pos": 1067, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1067", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8MLX0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1161, "chemical_mass": 130934.0, "gene_names": "Dmel\\CG3216;CG3216;Dmel\\CG3216;Dmel_CG3216;GYC", "protein_name": "Guanylate cyclase", "disease": [ { "disease_id": "DOID:0070316", "name": "Miura type epiphyseal chondrodysplasia", "description": "A bone developmental disease characterized by tall stature, scoliosis and macrodactyly of the great toes that has_material_basis_in heterozygous mutation in the NPR2 gene on chromosome 9p13.", "url": "https://disease-ontology.org/term/DOID:0070316", "evidence": [ { "id": "0070316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070316" } ], "weight": 0.0 }, { "disease_id": "DOID:0080006", "name": "bone development disease", "description": "A bone disease that results_in abnormal growth and development located_in bone or located_in cartilage.", "url": "https://disease-ontology.org/term/DOID:0080006", "evidence": [ { "id": "0080006", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080006" } ], "weight": 0.0 }, { "disease_id": "DOID:0080050", "name": "acromesomelic dysplasia, Maroteaux type", "description": "An acromesomelic dysplasia that has_material_basis_in homozygous or compound heterozygous mutation in the NPR2 gene, which encodes natriuretic peptide receptor B, on chromosome 9p13.", "url": "https://disease-ontology.org/term/DOID:0080050", "evidence": [ { "id": "0080050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080050" } ], "weight": 0.0 }, { "disease_id": "DOID:10825", "name": "essential hypertension", "description": "A hypertension with no known cause. It is the most common type of hypertension.", "url": "https://disease-ontology.org/term/DOID:10825", "evidence": [ { "id": "10825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10825" } ], "weight": 0.0 }, { "disease_id": "DOID:4480", "name": "achondroplasia", "description": "An osteochondrodysplasia that is characterized by short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and midface hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, genu varum, and trident hand and that has_material_basis_in heterozygous mutation in the fibroblast growth factor receptor-3 gene (FGFR3) on chromosome 4p16.3. Achondroplasia results in dwarfism due to the abnormal ossification of cartilage in the long bone.", "url": "https://disease-ontology.org/term/DOID:4480", "evidence": [ { "id": "4480", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4480" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "guanylate cyclase activity", "id": "GO:0004383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004383", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "peptide receptor activity", "id": "GO:0001653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001653", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "cGMP biosynthetic process", "id": "GO:0006182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006182", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" }, { "name": "receptor guanylyl cyclase signaling pathway", "id": "GO:0007168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007168", "evidence": [ { "database": "UniProtKB", "id": "Q8MLX0", "url": "https://www.uniprot.org/uniprotkb/Q8MLX0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VK51-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1112, "chemical_mass": 127938.0, "gene_names": "ACXA;AC62D;ACXA;AC;Ac62D;CG17176;DACXA;Dmel\\CG17176;Dmel_CG17176", "protein_name": "adenylate cyclase", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" } ], "biological_process": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "cyclic nucleotide biosynthetic process", "id": "GO:0009190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009190", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VK51", "url": "https://www.uniprot.org/uniprotkb/Q9VK51" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABI9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABI9", "url": "https://www.uniprot.org/uniprotkb/Q4ABI9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 181, "chemical_mass": 20947.0, "gene_names": "Dmel\\CG33725;CG33725;Dmel\\CG33725;Dmel_CG33725", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IMT8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 246, "chemical_mass": 27585.0, "gene_names": "veli;CG7662;D-veli;DLin-7;DLin7;Dmel\\CG7662;Dmel_CG7662;Dveli;Flin-7;LIN7;Lin-7;Lin7;Veli;d-Veli;dLin-7;dLin7;dVeli;lin-7;lin7;veli", "protein_name": "Protein lin-7 homolog", "disease": [], "cellular_component": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "subapical complex", "id": "GO:0035003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035003", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "MPP7-DLG1-LIN7 complex", "id": "GO:0097025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097025", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" }, { "name": "synaptic vesicle transport", "id": "GO:0048489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048489", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT8", "url": "https://www.uniprot.org/uniprotkb/Q8IMT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0KI93-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 630, "chemical_mass": 67470.0, "gene_names": "Whamy;CG12946;Dmel\\CG12946;Dmel_CG12946;Whamy;whamy", "protein_name": "", "disease": [], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "myoblast fusion", "id": "GO:0007520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007520", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "positive regulation of actin nucleation", "id": "GO:0051127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051127", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "Q0KI93", "url": "https://www.uniprot.org/uniprotkb/Q0KI93" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0KI93-1", "start_pos": "289", "end_pos": "289", "site_lbl": "Thr289", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 289, "start_aa": "Thr", "end_pos": 289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr289", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0KI93-1", "start_pos": "333", "end_pos": "333", "site_lbl": "Thr333", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 333, "start_aa": "Thr", "end_pos": 333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr333", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q0KI93-1", "start_pos": "492", "end_pos": "492", "site_lbl": "Thr492", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 492, "start_aa": "Thr", "end_pos": 492, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr492", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VAC9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAC9", "url": "https://www.uniprot.org/uniprotkb/Q9VAC9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 384, "chemical_mass": 40233.0, "gene_names": "cg7903;CG7903;Dmel\\CG7903;Dmel_CG7903;cg7903", "protein_name": "RRM domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9VAC9", "url": "https://www.uniprot.org/uniprotkb/Q9VAC9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IMH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 659, "chemical_mass": 74277.0, "gene_names": "Dmel\\CG31019;CG31019;Dmel\\CG31019;Dmel_CG31019", "protein_name": "Peptidase M14 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q8IMH9", "url": "https://www.uniprot.org/uniprotkb/Q8IMH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8INN6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 784, "chemical_mass": 86261.0, "gene_names": "Unc-115b;CG31332;CG9489;Dmel\\CG31332;Dmel_CG31332;Unc-115a;Unc-115b;anon-WO0140519.9;unc-115", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" } ], "biological_process": [ { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "Q8INN6", "url": "https://www.uniprot.org/uniprotkb/Q8INN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q59E63-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 396, "chemical_mass": 44685.0, "gene_names": "Dmel\\CG11406;CG11406;Dmel\\CG11406;Dmel_CG11406", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" }, { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q59E63", "url": "https://www.uniprot.org/uniprotkb/Q59E63" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0E8Q7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1597, "chemical_mass": 182701.0, "gene_names": "Eato;BG:DS00797.5;CG31731;CG7491;CG7559;D00797.5;DS00797.5;DmCG31731;Dmel\\CG31731;Dmel_CG31731;Eato", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" } ], "molecular_function": [ { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q0E8Q7", "url": "https://www.uniprot.org/uniprotkb/Q0E8Q7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VKT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKT4", "url": "https://www.uniprot.org/uniprotkb/Q9VKT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 409, "chemical_mass": 46997.0, "gene_names": "w-cup;BcDNA:AT31112;CG7363;Dmel\\CG7363;Dmel_CG7363;w-cup", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NFY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NFY9", "url": "https://www.uniprot.org/uniprotkb/M9NFY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 169, "chemical_mass": 19795.0, "gene_names": "Dmel\\CG43090;CG43090;Dmel\\CG43090;Dmel_CG43090", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9NFY9-1", "start_pos": "124", "end_pos": "124", "site_lbl": "Thr124", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 124, "start_aa": "Thr", "end_pos": 124, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr124", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9NFY9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9NFY9" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9NGE9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 362, "chemical_mass": 41401.0, "gene_names": "MB8.chrX.pasa.104-MIP02663;CG43088;Dmel\\CG43088;Dmel_CG43088;MB8.chrX.pasa.104-MIP02663;MB8.chrX.pasa.104", "protein_name": "DDE Tnp4 domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "pmid": "" }, { "name": "nuclease activity", "id": "GO:0004518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004518", "evidence": [ { "database": "UniProtKB", "id": "M9NGE9", "url": "https://www.uniprot.org/uniprotkb/M9NGE9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PBD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBD0", "url": "https://www.uniprot.org/uniprotkb/M9PBD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 35, "chemical_mass": 3870.0, "gene_names": "Dmel\\CG43220;CG43220;DMG8-chr2L.31.003;Dmel\\CG43220;Dmel_CG43220", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PBI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBI0", "url": "https://www.uniprot.org/uniprotkb/M9PBI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 182, "chemical_mass": 21187.0, "gene_names": "Dmel\\CG32313;CG32313;Dmel\\CG32313;Dmel_CG32313", "protein_name": "SCP domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "M9PBI0", "url": "https://www.uniprot.org/uniprotkb/M9PBI0" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "M9PBI0", "url": "https://www.uniprot.org/uniprotkb/M9PBI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PBM5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBM5", "url": "https://www.uniprot.org/uniprotkb/M9PBM5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 682, "chemical_mass": 77542.0, "gene_names": "NEST:bs23f04;BcDNA:GH10778;CG31920;CG33992;CG43755;Dmel\\CG43755;Dmel_CG43755;NEST:bs21f09;NEST:bs23f04;anon-WO0140519.62", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PBM5-1", "start_pos": "420", "end_pos": "420", "site_lbl": "Ser420", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 420, "start_aa": "Ser", "end_pos": 420, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser420", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PBM5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PBM5" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PBV9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PBV9", "url": "https://www.uniprot.org/uniprotkb/M9PBV9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 71, "chemical_mass": 8580.0, "gene_names": "Dmel\\CG43886;CG43886;Dmel\\CG43886;Dmel_CG43886;lincRNA.469", "protein_name": "Rod shape-determining protein MreD", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCF9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 646, "chemical_mass": 70350.0, "gene_names": "Dmel\\CG9541;CG9541;Dmel\\CG9541;Dmel_CG9541", "protein_name": "Adenylate kinase isoenzyme 5", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" }, { "name": "UMP kinase activity", "id": "GO:0033862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033862", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" } ], "biological_process": [ { "name": "UDP biosynthetic process", "id": "GO:0006225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006225", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" }, { "name": "CDP biosynthetic process", "id": "GO:0046705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046705", "evidence": [ { "database": "UniProtKB", "id": "M9PCF9", "url": "https://www.uniprot.org/uniprotkb/M9PCF9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 587, "chemical_mass": 62565.0, "gene_names": "Sox21b;CG13483;CG32139;CG6419;Dmel\\CG32139;Dmel_CG32139;SOXB2.2;Sox B2-2;Sox21B;Sox21b;SoxB2.2", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PCG2", "url": "https://www.uniprot.org/uniprotkb/M9PCG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PCG2-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "M9PCG2-1", "start_pos": "359", "end_pos": "359", "site_lbl": "Thr359", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 359, "start_aa": "Thr", "end_pos": 359, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr359", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCH7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCH7", "url": "https://www.uniprot.org/uniprotkb/M9PCH7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 54, "chemical_mass": 6691.0, "gene_names": "Dmel\\CG43815;CG43815;Dmel\\CG43815;Dmel_CG43815;FBgn0264363", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCI3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCI3", "url": "https://www.uniprot.org/uniprotkb/M9PCI3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 84, "chemical_mass": 9679.0, "gene_names": "Dmel\\CG43703;CG43703;Dmel\\CG43703;Dmel_CG43703", "protein_name": "BPTI/Kunitz inhibitor domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "M9PCI3", "url": "https://www.uniprot.org/uniprotkb/M9PCI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCP3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1318, "chemical_mass": 147820.0, "gene_names": "mdcds_8484;CG9044;CT25972;Dmel\\CG9044;Dmel_CG9044;mdcds_8484", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "M9PCP3", "url": "https://www.uniprot.org/uniprotkb/M9PCP3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCS7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCS7", "url": "https://www.uniprot.org/uniprotkb/M9PCS7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 37, "chemical_mass": 3912.0, "gene_names": "Dmel\\CG43813;CG43813;Dmel\\CG43813;Dmel_CG43813", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 648, "chemical_mass": 73696.0, "gene_names": "Ir31a;31a;CG31718;DmelIR31a;Dmel\\CG31718;Dmel_CG31718;IR31a;Ir31a", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus involved in sensory perception", "id": "GO:0050907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050907", "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "M9PCT4", "url": "https://www.uniprot.org/uniprotkb/M9PCT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PCZ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 761, "chemical_mass": 81614.0, "gene_names": "SoxN;CG18024;DM64;Dmel\\CG18024;Dmel_CG18024;SOX29F;SOXB1;Sox B1;SoxN;Sry-rDM64;soxNeuro;soxN", "protein_name": "", "disease": [ { "disease_id": "DOID:0111779", "name": "X-linked panhypopituitarism", "description": "A combined pituitary hormone deficiency that has_material_basis_in duplications in the SOX3 gene on chromosome Xq27.1.", "url": "https://disease-ontology.org/term/DOID:0111779", "evidence": [ { "id": "0111779", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111779" } ], "weight": 0.0 } ], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "regulation of neurogenesis", "id": "GO:0050767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050767", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "regulation of neural precursor cell proliferation", "id": "GO:2000177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000177", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "segment polarity determination", "id": "GO:0007367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007367", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "chitin-based larval cuticle pattern formation", "id": "GO:0035293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035293", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "M9PCZ7", "url": "https://www.uniprot.org/uniprotkb/M9PCZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PCZ7-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 621, "start_aa": "Thr", "end_pos": 621, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr621", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PE01-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 538, "chemical_mass": 61617.0, "gene_names": "Eip63E;CG10579;Dmel\\CG10579;Dmel_CG10579;EIP63E;Eip63E;L63;PFTAIRE;Pftaire;cdc2-63E", "protein_name": "cyclin-dependent kinase", "disease": [ { "disease_id": "DOID:0050453", "name": "lissencephaly", "description": "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation.", "url": "https://disease-ontology.org/term/DOID:0050453", "evidence": [ { "id": "0050453", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050453" } ], "weight": 0.0 }, { "disease_id": "DOID:0112231", "name": "lissencephaly 7 with cerebellar hypoplasia", "description": "A lissencephaly characterized by lack of psychomotor development, facial dysmorphism, arthrogryposis, and early-onset intractable seizures resulting in death in infancy that has_material_basis_in homozygous or compound heterozygous mutation in the CDK5 gene on chromosome 7q36.1.", "url": "https://disease-ontology.org/term/DOID:0112231", "evidence": [ { "id": "0112231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112231" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" } ], "biological_process": [ { "name": "developmental growth", "id": "GO:0048589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048589", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "regulation of cell cycle phase transition", "id": "GO:1901987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901987", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "embryonic development via the syncytial blastoderm", "id": "GO:0001700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001700", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "instar larval development", "id": "GO:0002168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002168", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" }, { "name": "metamorphosis", "id": "GO:0007552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007552", "evidence": [ { "database": "UniProtKB", "id": "M9PE01", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PEA4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEA4", "url": "https://www.uniprot.org/uniprotkb/M9PEA4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 379, "chemical_mass": 43210.0, "gene_names": "Dmel\\CG10479;CG10479;Dmel\\CG10479;Dmel_CG10479", "protein_name": "SH2 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PED9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PED9", "url": "https://www.uniprot.org/uniprotkb/M9PED9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 486, "chemical_mass": 54363.0, "gene_names": "Dmel\\CG15412;CG15412;Dmel\\CG15412;Dmel_CG15412", "protein_name": "", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "M9PED9", "url": "https://www.uniprot.org/uniprotkb/M9PED9" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "M9PED9", "url": "https://www.uniprot.org/uniprotkb/M9PED9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KU89-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1904, "chemical_mass": 210734.0, "gene_names": "Pura;CG33167;CG33275;CG7511;CG7513;CG7515;CG7520;Dmel\\CG33275;Dmel_CG33275;Pura", "protein_name": "", "disease": [], "biological_process": [ { "name": "regulation of locomotor rhythm", "id": "GO:1904059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904059", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q7KU89", "url": "https://www.uniprot.org/uniprotkb/Q7KU89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KU89-1", "start_pos": "1195", "end_pos": "1195", "site_lbl": "Thr1195", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1195, "start_aa": "Thr", "end_pos": 1195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1195", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KU89-1", "start_pos": "741", "end_pos": "741", "site_lbl": "Thr741", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 741, "start_aa": "Thr", "end_pos": 741, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr741", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PEG1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEG1", "url": "https://www.uniprot.org/uniprotkb/M9PEG1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 694, "chemical_mass": 75620.0, "gene_names": "Dmel\\CG44195;CG44195;Dmel\\CG44195;Dmel_CG44195", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PEG1-1", "start_pos": "297", "end_pos": "297", "site_lbl": "Thr297", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 297, "start_aa": "Thr", "end_pos": 297, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr297", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PEG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEG2", "url": "https://www.uniprot.org/uniprotkb/M9PEG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 273, "chemical_mass": 30852.0, "gene_names": "Dmel\\CG13288;dmCG13288;CG13288;Dmel\\CG13288;Dmel_CG13288;dmCG13288", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PEG2", "url": "https://www.uniprot.org/uniprotkb/M9PEG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PEJ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEJ6", "url": "https://www.uniprot.org/uniprotkb/M9PEJ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 105, "chemical_mass": 11243.0, "gene_names": "Dmel\\CG43915;CG43915;Dmel\\CG43915;Dmel_CG43915", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PEJ6", "url": "https://www.uniprot.org/uniprotkb/M9PEJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PEP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1703, "chemical_mass": 188332.0, "gene_names": "Ac13E;AC 13E;AC13E;Ac13E;Ac35C;CG9210;DAC9;Dmel\\CG9210;Dmel_CG9210;ac13e;dADCY9", "protein_name": "Adenylate cyclase type 9", "disease": [ { "disease_id": "DOID:12716", "name": "newborn respiratory distress syndrome", "description": "A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.", "url": "https://disease-ontology.org/term/DOID:12716", "evidence": [ { "id": "12716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12716" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness.", "url": "https://disease-ontology.org/term/DOID:9415", "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" } ], "biological_process": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "M9PEP2", "url": "https://www.uniprot.org/uniprotkb/M9PEP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PEY3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PEY3", "url": "https://www.uniprot.org/uniprotkb/M9PEY3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 81, "chemical_mass": 9573.0, "gene_names": "Dmel\\CG43993;CG43993;Dmel\\CG43993;Dmel_CG43993", "protein_name": "Seminal fluid protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PF61-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 350, "chemical_mass": 40137.0, "gene_names": "Ar1;34F4T;AR;Akr1B;CG6084;Dmel\\CG6084;ESTS:34F4T;dAR1", "protein_name": "Aldo-keto reductase 1B", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:4195", "name": "hyperglycemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4195", "evidence": [ { "id": "4195", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4195" } ], "weight": 0.0 }, { "disease_id": "DOID:4500", "name": "hypokalemia", "description": "", "url": "https://disease-ontology.org/term/DOID:4500", "evidence": [ { "id": "4500", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4500" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision.", "url": "https://disease-ontology.org/term/DOID:83", "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9743", "name": "diabetic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:9743", "evidence": [ { "id": "9743", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9743" } ], "weight": 0.0 }, { "disease_id": "DOID:9870", "name": "galactosemia", "description": "A carbohydrate metabolic disorder that involves a defect in galactose metabolism resulting in toxic levels of galactose 1-phosphate in various tissues.", "url": "https://disease-ontology.org/term/DOID:9870", "evidence": [ { "id": "9870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9870" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" } ], "molecular_function": [ { "name": "aldose reductase (NADPH) activity", "id": "GO:0004032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004032", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "L-glucuronate reductase activity", "id": "GO:0047939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047939", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "prostaglandin H2 endoperoxidase reductase activity", "id": "GO:0036130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036130", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "glycerol dehydrogenase (NADP+) activity", "id": "GO:0047956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047956", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "allyl-alcohol dehydrogenase activity", "id": "GO:0047655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047655", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" } ], "biological_process": [ { "name": "sorbitol biosynthetic process", "id": "GO:0006061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006061", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "fructose biosynthetic process", "id": "GO:0046370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046370", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "D-glucuronate catabolic process to D-xylulose 5-phosphate", "id": "GO:0019640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019640", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" }, { "name": "polyol biosynthetic process", "id": "GO:0046173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046173", "evidence": [ { "database": "UniProtKB", "id": "M9PF61", "url": "https://www.uniprot.org/uniprotkb/M9PF61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PF81-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF81", "url": "https://www.uniprot.org/uniprotkb/M9PF81" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 356, "chemical_mass": 38795.0, "gene_names": "Dmel\\CG7906;CG7906;Dmel\\CG7906;Dmel_CG7906", "protein_name": "Kazal-like domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PF84-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 818, "chemical_mass": 90298.0, "gene_names": "klu;CG12296;Dmel\\CG12296;Dmel_CG12296;KLU;Klu;P09036;klu;l(3)09036;l(3)10052", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "neurogenesis", "id": "GO:0022008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022008", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "neuronal stem cell population maintenance", "id": "GO:0097150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097150", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "regulation of stem cell division", "id": "GO:2000035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000035", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "regulation of neuroblast proliferation", "id": "GO:1902692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902692", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "R7 cell differentiation", "id": "GO:0045466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045466", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "positive regulation of compound eye retinal cell programmed cell death", "id": "GO:0046672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046672", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "neuroblast development", "id": "GO:0014019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014019", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "sensory organ precursor cell fate determination", "id": "GO:0016360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016360", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "larval feeding behavior", "id": "GO:0030536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030536", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PF84", "url": "https://www.uniprot.org/uniprotkb/M9PF84" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PF84-1", "start_pos": "594", "end_pos": "594", "site_lbl": "Thr594", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 594, "start_aa": "Thr", "end_pos": 594, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr594", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PFA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 412, "chemical_mass": 46885.0, "gene_names": "Dmel\\CG10654;CG10654;Dmel\\CG10654;Dmel_CG10654", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "M9PFA9", "url": "https://www.uniprot.org/uniprotkb/M9PFA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PFK3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFK3", "url": "https://www.uniprot.org/uniprotkb/M9PFK3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 240, "chemical_mass": 26503.0, "gene_names": "BcDNA:RH23514;BcDNA:RH23514;CG16743;Dmel\\CG16743;Dmel_CG16743", "protein_name": "CG16743 protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q86BI6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 31993.0, "gene_names": "Dmel\\CG33061;CG13057;CG33061;Dmel\\CG33061;Dmel_CG33061", "protein_name": "Trimeric intracellular cation channel type B", "disease": [ { "disease_id": "DOID:0110343", "name": "osteogenesis imperfecta type 14", "description": "An osteogenesis imperfecta that has_material_basis_in mutation in the TMEM38B gene on chromosome 9q31.", "url": "https://disease-ontology.org/term/DOID:0110343", "evidence": [ { "id": "0110343", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110343" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" } ], "molecular_function": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" }, { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" } ], "biological_process": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q86BI6", "url": "https://www.uniprot.org/uniprotkb/Q86BI6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PFR6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 188, "chemical_mass": 20453.0, "gene_names": "mbf1;BcDNA:GH10148;BcDNA:GM01267;CG4143;Dmel\\CG4143;Dmel_CG4143;MBF-1;MBF1;MRE4;Mbf-1;Mbf1;mbf1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "M9PFR6", "url": "https://www.uniprot.org/uniprotkb/M9PFR6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PFU2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 889, "chemical_mass": 96043.0, "gene_names": "Crtc;CG6064;CRTC;Crtc;Dmel\\CG6064;Dmel_CG6064;MTORC1;ORE-12;TOR-C2;TORC1;TORC2;TORC;Tor-C2;cg6064;crtc;dTORC2;dTORC;mTORC1;mTORC", "protein_name": "", "disease": [ { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "cAMP response element binding protein binding", "id": "GO:0008140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008140", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "cellular response to cAMP", "id": "GO:0071320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071320", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "M9PFU2", "url": "https://www.uniprot.org/uniprotkb/M9PFU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PFU4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFU4", "url": "https://www.uniprot.org/uniprotkb/M9PFU4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 374, "chemical_mass": 42925.0, "gene_names": "Dmel\\CG44006;CG34252;CG44006;Dmel\\CG44006;Dmel_CG44006", "protein_name": "F-box domain-containing protein", "disease": [], "molecular_function": [ { "name": "SCF ubiquitin ligase complex binding", "id": "GO:1905761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905761", "evidence": [ { "database": "UniProtKB", "id": "M9PFU4", "url": "https://www.uniprot.org/uniprotkb/M9PFU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PFX3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PFX3", "url": "https://www.uniprot.org/uniprotkb/M9PFX3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 118, "chemical_mass": 13976.0, "gene_names": "Dmel\\CG43954;CG43954;Dmel\\CG43954;Dmel_CG43954", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PFX3", "url": "https://www.uniprot.org/uniprotkb/M9PFX3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PG08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 783, "chemical_mass": 89669.0, "gene_names": "RhoBTB;28574635;CG5701;Dmel\\CG5701;Dmel_CG5701;RhoBTB;RhoGTPase;RhoX", "protein_name": "", "disease": [ { "disease_id": "DOID:0070375", "name": "developmental and epileptic encephalopathy 64", "description": "A developmental and epileptic encephalopathy characterized by infantile onset of seizures, severe intellectual disabilities, impaired motor functions, movement disorders, and postnatal microcephaly that has_material_basis_in heterozygous mutation in the RHOBTB2 gene on chromosome 8p21.", "url": "https://disease-ontology.org/term/DOID:0070375", "evidence": [ { "id": "0070375", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070375" } ], "weight": 0.0 } ], "biological_process": [ { "name": "developmental process involved in reproduction", "id": "GO:0003006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003006", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "cortical cytoskeleton organization", "id": "GO:0030865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030865", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "ameboidal-type cell migration", "id": "GO:0001667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001667", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "cellular process involved in reproduction in multicellular organism", "id": "GO:0022412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022412", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "melanotic encapsulation of foreign target", "id": "GO:0035011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035011", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "hemocyte migration", "id": "GO:0035099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035099", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "M9PG08", "url": "https://www.uniprot.org/uniprotkb/M9PG08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PG08-1", "start_pos": "27", "end_pos": "27", "site_lbl": "Thr27", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 27, "start_aa": "Thr", "end_pos": 27, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr27", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "M9PG08", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=M9PG08" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PGH7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1657, "chemical_mass": 183541.0, "gene_names": "G9a;CG2995;Dmel\\CG2995;Dmel_CG2995;EG:BACR37P7.2;EHMT;G9ae;G9a;cab65850 G9a Dm;dG9a", "protein_name": "", "disease": [ { "disease_id": "DOID:0050156", "name": "idiopathic pulmonary fibrosis", "description": "A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.", "url": "https://disease-ontology.org/term/DOID:0050156", "evidence": [ { "id": "0050156", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050156" } ], "weight": 0.0 }, { "disease_id": "DOID:0050696", "name": "fetal alcohol spectrum disorder", "description": "A specific developmental disorder and physical disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of alcohol during pregnancy.", "url": "https://disease-ontology.org/term/DOID:0050696", "evidence": [ { "id": "0050696", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050696" } ], "weight": 0.0 }, { "disease_id": "DOID:0060352", "name": "Kleefstra syndrome 1", "description": "A Kleefstra syndrome that is characterized by severe mental retardation, hypotonia, microcephaly, epileptic seizures, flat face with hypertelorism, synophrys, anteverted nares, everted lower lip, carp mouth with macroglossia, and heart defects and that has_material_basis_in a microdeletion in the chromosome region 9q34.3 or by a point mutation in the EHMT1 gene located in that region.", "url": "https://disease-ontology.org/term/DOID:0060352", "evidence": [ { "id": "0060352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060352" } ], "weight": 0.0 }, { "disease_id": "DOID:0080597", "name": "Kleefstra syndrome", "description": "A syndrome that is characterized by developmental delay and intellectual disability, severely limited or absent speech, and weak muscle tone.", "url": "https://disease-ontology.org/term/DOID:0080597", "evidence": [ { "id": "0080597", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080597" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:934", "name": "viral infectious disease", "description": "A disease by infectious agent that results in infection, has_material_basis_in Viruses.", "url": "https://disease-ontology.org/term/DOID:934", "evidence": [ { "id": "934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:934" } ], "weight": 0.0 }, { "disease_id": "DOID:986", "name": "alopecia areata", "description": "An autoimmune disease resulting in the loss of hair on the scalp and elsewhere on the body initially causing bald spots.", "url": "https://disease-ontology.org/term/DOID:986", "evidence": [ { "id": "986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:986" } ], "weight": 0.0 } ], "biological_process": [ { "name": "habituation", "id": "GO:0046959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046959", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "short-term memory", "id": "GO:0007614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007614", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "larval locomotory behavior", "id": "GO:0008345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008345", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "facultative heterochromatin formation", "id": "GO:0140718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140718", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "polytene chromosome interband", "id": "GO:0005705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005705", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K9 methyltransferase activity", "id": "GO:0046974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046974", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K9 monomethyltransferase activity", "id": "GO:0140948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140948", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K9 dimethyltransferase activity", "id": "GO:0140942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140942", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K27 monomethyltransferase activity", "id": "GO:0140953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140953", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K9 trimethyltransferase activity", "id": "GO:0140949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140949", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H4 methyltransferase activity", "id": "GO:0140939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140939", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K27 trimethyltransferase activity", "id": "GO:0140951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140951", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" }, { "name": "histone H3K27 dimethyltransferase activity", "id": "GO:0140952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140952", "evidence": [ { "database": "UniProtKB", "id": "M9PGH7", "url": "https://www.uniprot.org/uniprotkb/M9PGH7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PGR0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PGR0", "url": "https://www.uniprot.org/uniprotkb/M9PGR0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 176, "chemical_mass": 19794.0, "gene_names": "Dlip1;CG15367;DIP1;Dip1;Dlip1;Dmel\\CG15367;Dmel_CG15367;dip1;dlip", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PGR0", "url": "https://www.uniprot.org/uniprotkb/M9PGR0" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PGR0", "url": "https://www.uniprot.org/uniprotkb/M9PGR0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHC0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHC0", "url": "https://www.uniprot.org/uniprotkb/M9PHC0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 261, "chemical_mass": 30604.0, "gene_names": "Dmel\\CG32718;CG32718;Dmel\\CG32718;Dmel_CG32718", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PH26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 191, "chemical_mass": 21445.0, "gene_names": "HLH4C;CG3052;Dmel\\CG3052;Dmel_CG3052;DroNHLH;EG:84H4.2;HLH4C;bHLH36", "protein_name": "", "disease": [], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "M9PH26", "url": "https://www.uniprot.org/uniprotkb/M9PH26" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "M9PH26-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHF7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHF7", "url": "https://www.uniprot.org/uniprotkb/M9PHF7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 432, "chemical_mass": 47654.0, "gene_names": "Dmel\\CG12992;CG12992;Dmel\\CG12992;Dmel_CG12992", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHI7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 261, "chemical_mass": 28835.0, "gene_names": "kri;CG5537;Dmel\\CG5537;Dmel_CG5537;anon-EST:Posey275;kri;uprt", "protein_name": "Uracil phosphoribosyltransferase homolog", "disease": [], "molecular_function": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "pmid": "" }, { "name": "uracil phosphoribosyltransferase activity", "id": "GO:0004845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004845", "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PHI7", "url": "https://www.uniprot.org/uniprotkb/M9PHI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHK6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHK6", "url": "https://www.uniprot.org/uniprotkb/M9PHK6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 586, "chemical_mass": 64914.0, "gene_names": "Dmel\\CG14221;CG14221;Dmel\\CG14221;Dmel_CG14221", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHS8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 519, "chemical_mass": 60183.0, "gene_names": "Dmel\\CG9784;CG9784;Dmel\\CG9784;Dmel_CG9784;IPP;lincRNA.S9473", "protein_name": "Inositol polyphosphate-related phosphatase domain-containing protein", "disease": [ { "disease_id": "DOID:0050588", "name": "muscular dystrophy-dystroglycanopathy type B1", "description": "A congenital muscular dystrophy characterized by muscle weakness, cognitive impairment and brain abnormalities and has_material_basis_in mutation to the POMT1 gene that encodes O-mannosyltransferase.", "url": "https://disease-ontology.org/term/DOID:0050588", "evidence": [ { "id": "0050588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050588" } ], "weight": 0.0 }, { "disease_id": "DOID:0080197", "name": "congenital muscular dystrophy with cataracts and intellectual disability", "description": "A congenital muscular dystrophy characterized by onset of progressive muscle weakness in early childhood with autosomal recessive inheritance that has_material_basis_in homozygous or compound heterozygous mutation in the INPP5K gene (607875) on chromosome 17p13.", "url": "https://disease-ontology.org/term/DOID:0080197", "evidence": [ { "id": "0080197", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080197" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" } ], "biological_process": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "id": "GO:0004439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004439", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0034485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034485", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" }, { "name": "inositol trisphosphate phosphatase activity", "id": "GO:0046030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046030", "evidence": [ { "database": "UniProtKB", "id": "M9PHS8", "url": "https://www.uniprot.org/uniprotkb/M9PHS8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHT8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 496, "chemical_mass": 55070.0, "gene_names": "CT15971;CG4991;CT15971;Dmel\\CG4991;Dmel_CG4991", "protein_name": "Amino acid transporter transmembrane domain-containing protein", "disease": [ { "disease_id": "DOID:0112265", "name": "iminoglycinuria", "description": "A renal tubular transport disease characterized by impaired renal tube reabsorption of proline, hydroxyproline and glycine and elevated urine levels of the imino acids and glycine that has_material_basis_in homozygous mutation in SLC36A2 on chromosome 5q33.1 combined with either heterozygous mutation in SLC6A20 gene on chromosome 3p21.31 or homozygous mutation in SLC6A19 on chromosome 5p15.33.", "url": "https://disease-ontology.org/term/DOID:0112265", "evidence": [ { "id": "0112265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112265" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" }, { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" } ], "cellular_component": [ { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "M9PHT8", "url": "https://www.uniprot.org/uniprotkb/M9PHT8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PHX0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PHX0", "url": "https://www.uniprot.org/uniprotkb/M9PHX0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 345, "chemical_mass": 39524.0, "gene_names": "Dmel\\CG43843;CG15049;CG43843;Dmel\\CG43843;Dmel_CG43843", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PI41-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1858, "chemical_mass": 211780.0, "gene_names": "sti;CG10522;CIT-K;CIT;Citron K;Citron;DCK;Dmel\\CG10522;Dmel_CG10522;STI;anon-WO0118547.388;cit;ck;dck;l(3)7m-62;l(3)7m62;l(3)SG21;sti/Citron;sti", "protein_name": "non-specific serine/threonine protein kinase", "disease": [ { "disease_id": "DOID:0070288", "name": "primary autosomal recessive microcephaly 17", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the CIT gene on chromosome 12q24.", "url": "https://disease-ontology.org/term/DOID:0070288", "evidence": [ { "id": "0070288", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070288" } ], "weight": 0.0 }, { "disease_id": "DOID:0070297", "name": "primary microcephaly", "description": "A microcephaly characterized by microcephaly present at birth, where the brain is small but has normal architecture, and nonprogressive mental retardation.", "url": "https://disease-ontology.org/term/DOID:0070297", "evidence": [ { "id": "0070297", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070297" } ], "weight": 0.0 }, { "disease_id": "DOID:0081292", "name": "traumatic brain injury", "description": "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head.", "url": "https://disease-ontology.org/term/DOID:0081292", "evidence": [ { "id": "0081292", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081292" } ], "weight": 0.0 }, { "disease_id": "DOID:10907", "name": "microcephaly", "description": "A congenital nervous system abnormality that is characterized by a significantly smaller than normal head in infants.", "url": "https://disease-ontology.org/term/DOID:10907", "evidence": [ { "id": "10907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10907" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "actomyosin contractile ring", "id": "GO:0005826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005826", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "actomyosin contractile ring assembly", "id": "GO:0000915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000915", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "regulation of cytokinesis, actomyosin contractile ring assembly", "id": "GO:2000431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000431", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "male meiosis cytokinesis", "id": "GO:0007112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007112", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" }, { "name": "ventral cord development", "id": "GO:0007419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007419", "evidence": [ { "database": "UniProtKB", "id": "M9PI41", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q59E08-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E08", "url": "https://www.uniprot.org/uniprotkb/Q59E08" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 271, "chemical_mass": 31109.0, "gene_names": "Jhbp6;BcDNA:LP08817;CG14457;CG18618;Dmel\\CG14457;Dmel_CG14457;JHBP6;Jhbp6", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q59E08", "url": "https://www.uniprot.org/uniprotkb/Q59E08" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q59E08", "url": "https://www.uniprot.org/uniprotkb/Q59E08" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "M9PJS6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "M9PJS6", "url": "https://www.uniprot.org/uniprotkb/M9PJS6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 603, "chemical_mass": 65049.0, "gene_names": "CG17602;Dmel\\CG17600;CG17600;CG17602;Dmel\\CG17600;Dmel_CG17600", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "M9PJS6", "url": "https://www.uniprot.org/uniprotkb/M9PJS6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "O76888-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O76888", "url": "https://www.uniprot.org/uniprotkb/O76888" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 116, "chemical_mass": 12646.0, "gene_names": "Dmel\\CG14795;CG14795;Dmel\\CG14795;Dmel_CG14795;EG:196F3.3", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "O96532-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 535, "chemical_mass": 59417.0, "gene_names": "Rad17;24;CG7825;DmRad17/24;Dmel\\CG7825;Dmel_CG7825;Rad17", "protein_name": "", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "Rad17 RFC-like complex", "id": "GO:0031389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031389", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "chromosome, telomeric repeat region", "id": "GO:0140445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140445", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "mitotic intra-S DNA damage checkpoint signaling", "id": "GO:0031573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031573", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "O96532", "url": "https://www.uniprot.org/uniprotkb/O96532" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "O96532-1", "start_pos": "136", "end_pos": "136", "site_lbl": "Thr136", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "O96532-1", "start_pos": "28", "end_pos": "28", "site_lbl": "Thr28", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0E8E7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 276, "chemical_mass": 31468.0, "gene_names": "Tsen34;CG13470;CG33260;Dmel\\CG33260;Dmel_CG33260;TSEN34;Tsen34", "protein_name": "tRNA-splicing endonuclease subunit Sen34", "disease": [ { "disease_id": "DOID:0060269", "name": "pontocerebellar hypoplasia type 2C", "description": "A severe pontocerebellar hypoplasia that is characterized by progressive microcephaly, extrapyramidal dyskinesia, seizure and failure to thrive, has_material_basis_in autosomal recessive inheritance of mutation in the TSEN34 gene.", "url": "https://disease-ontology.org/term/DOID:0060269", "evidence": [ { "id": "0060269", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060269" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" }, { "name": "tRNA-intron endonuclease complex", "id": "GO:0000214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000214", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" }, { "name": "tRNA-type intron splice site recognition and cleavage", "id": "GO:0000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000379", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" }, { "name": "tRNA-intron lyase activity", "id": "GO:0000213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000213", "evidence": [ { "database": "UniProtKB", "id": "Q0E8E7", "url": "https://www.uniprot.org/uniprotkb/Q0E8E7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0E8H9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 622, "chemical_mass": 70558.0, "gene_names": "Hexo1;CG1318;DmHex1;Dmel\\CG1318;Dmel_CG1318;HEX 1;HEX1;HEXO1;Hexo1", "protein_name": "beta-N-acetylhexosaminidase", "disease": [ { "disease_id": "DOID:12377", "name": "spinal muscular atrophy", "description": "A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.", "url": "https://disease-ontology.org/term/DOID:12377", "evidence": [ { "id": "12377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12377" } ], "weight": 0.0 }, { "disease_id": "DOID:3211", "name": "lysosomal storage disease", "description": "An inherited metabolic disorder that involve an abnormal accumulation of substances inside the lysosome resulting from defects in lysosomal function.", "url": "https://disease-ontology.org/term/DOID:3211", "evidence": [ { "id": "3211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3211" } ], "weight": 0.0 }, { "disease_id": "DOID:3320", "name": "Tay-Sachs disease", "description": "A GM2 gangliosidosis that is characterized onset in infancy of developmental retardation, followed by paralysis, dementia and blindness, with death in the second or third year of life and has_material_basis_in homozygous or compound heterozygous mutation in the alpha subunit of the hexosaminidase A gene (HEXA) on chromosome 15q23.", "url": "https://disease-ontology.org/term/DOID:3320", "evidence": [ { "id": "3320", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3320" } ], "weight": 0.0 }, { "disease_id": "DOID:3323", "name": "Sandhoff disease", "description": "A GM2 gangliosidosis that is characterized by an accumulation of GM2 gangliosides, particularly in neurons, and that has_material_basis_in mutation in the beta subunit of hexosaminidase (HEXB) on chromosome 5q13.", "url": "https://disease-ontology.org/term/DOID:3323", "evidence": [ { "id": "3323", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3323" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "glycosaminoglycan metabolic process", "id": "GO:0030203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030203", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "chondroitin sulfate proteoglycan catabolic process", "id": "GO:0030207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030207", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "chitin catabolic process", "id": "GO:0006032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006032", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "rhodopsin biosynthetic process", "id": "GO:0016063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016063", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" } ], "molecular_function": [ { "name": "beta-N-acetylglucosaminidase activity", "id": "GO:0016231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016231", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" }, { "name": "beta-N-acetylhexosaminidase activity", "id": "GO:0004563", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004563", "evidence": [ { "database": "UniProtKB", "id": "Q0E8H9", "url": "https://www.uniprot.org/uniprotkb/Q0E8H9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0E8H9-1", "start_pos": "144", "end_pos": "144", "site_lbl": "Thr144", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 144, "start_aa": "Thr", "end_pos": 144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr144", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0E8V6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 384, "chemical_mass": 43396.0, "gene_names": "Spn28Da;CG12318;CG31902;Dmel\\CG31902;Dmel_CG31902;Spn28Da", "protein_name": "", "disease": [ { "disease_id": "DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract.", "url": "https://disease-ontology.org/term/DOID:0050589", "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ], "weight": 0.0 }, { "disease_id": "DOID:0050831", "name": "familial encephalopathy with neuroserpin inclusion bodies", "description": "A neurodegenerative disease that is characterized by intraneuronal inclusions of mutant neuroserpin resulting in progressive encephalopathy, dementia and seizures and has_material_basis_in a mutation in the SERPINI1 gene inherited in an in autosomal dominant pattern.", "url": "https://disease-ontology.org/term/DOID:0050831", "evidence": [ { "id": "0050831", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050831" } ], "weight": 0.0 }, { "disease_id": "DOID:0051054", "name": "coarctation of the aorta", "description": "A congenital heart disease that is characterized by the luminal narrowing of the thoracic aortic arch, typically located just beyond the left subclavian artery. This narrowing creates an obstruction that can lead to significant cardiovascular complications, including systemic hypertension, left ventricular hypertrophy, and eventually heart failure.", "url": "https://disease-ontology.org/term/DOID:0051054", "evidence": [ { "id": "0051054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051054" } ], "weight": 0.0 }, { "disease_id": "DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen.", "url": "https://disease-ontology.org/term/DOID:0051061", "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ], "weight": 0.0 }, { "disease_id": "DOID:0060186", "name": "chemical colitis", "description": "A colitis caused_by introduction of various chemicals.", "url": "https://disease-ontology.org/term/DOID:0060186", "evidence": [ { "id": "0060186", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060186" } ], "weight": 0.0 }, { "disease_id": "DOID:0060189", "name": "ileitis", "description": "An inflammatory bowel disease characterized by inflammation located_in ileum, has_symptom diarrhea, has_symptom abdominal pain, often in the right lower quadrant, has_symptom weight loss.", "url": "https://disease-ontology.org/term/DOID:0060189", "evidence": [ { "id": "0060189", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060189" } ], "weight": 0.0 }, { "disease_id": "DOID:0060224", "name": "atrial fibrillation", "description": "A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.", "url": "https://disease-ontology.org/term/DOID:0060224", "evidence": [ { "id": "0060224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060224" } ], "weight": 0.0 }, { "disease_id": "DOID:0060903", "name": "thrombosis", "description": "A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.", "url": "https://disease-ontology.org/term/DOID:0060903", "evidence": [ { "id": "0060903", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060903" } ], "weight": 0.0 }, { "disease_id": "DOID:0070508", "name": "metabolic dysfunction and alcohol associated liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and elevated alcohol consumption. This disease is distinguished from MASLD by increased alcohol consumption and from ALD by the evidence of one or more of the specified cardiometabolic risk factors. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0070508", "evidence": [ { "id": "0070508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070508" } ], "weight": 0.0 }, { "disease_id": "DOID:0070555", "name": "Nagashima-type palmoplantar keratosis", "description": "A nonepidermolytic palmoplantar keratoderma characterized by mild, well-demarcated, diffuse erythematous hyperkeratosis that is nonprogressive after the second decade of life which extends onto the dorsal surfaces of the palms and feet and the Achilles tendon area, with a high frequency of hyperhidrosis on the palms and soles and without flexion contractures or constricting bands that has_material_basis_in homozygous or compound heterozygous mutation in the SERPINB7 gene on chromosome 18q21.33.", "url": "https://disease-ontology.org/term/DOID:0070555", "evidence": [ { "id": "0070555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070555" } ], "weight": 0.0 }, { "disease_id": "DOID:0080322", "name": "polycystic kidney disease", "description": "A cystic kidney disease that is characterized by the growth of fluid-filled cysts in the kidneys that reduces kidney function and may lead to kidney failure.", "url": "https://disease-ontology.org/term/DOID:0080322", "evidence": [ { "id": "0080322", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080322" } ], "weight": 0.0 }, { "disease_id": "DOID:0090030", "name": "corticosteroid-binding globulin deficiency", "description": "An adrenal gland disease characterized by decreased levels of serum corticosteroid-binding globulin and cortisol, and in some cases hypo- or hypertension, and muscle fatigue that has_material_basis_in heterozygous or homozygous mutation in the SERPINA6 gene on chromosome 14q32.", "url": "https://disease-ontology.org/term/DOID:0090030", "evidence": [ { "id": "0090030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090030" } ], "weight": 0.0 }, { "disease_id": "DOID:10159", "name": "osteonecrosis", "description": "An ischemic bone disease that results_in necrosis located_in bone.", "url": "https://disease-ontology.org/term/DOID:10159", "evidence": [ { "id": "10159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10159" } ], "weight": 0.0 }, { "disease_id": "DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.", "url": "https://disease-ontology.org/term/DOID:10591", "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:10762", "name": "portal hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:10762", "evidence": [ { "id": "10762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10762" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:10808", "name": "gastric ulcer", "description": "", "url": "https://disease-ontology.org/term/DOID:10808", "evidence": [ { "id": "10808", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10808" } ], "weight": 0.0 }, { "disease_id": "DOID:10952", "name": "nephritis", "description": "A kidney disease that is characterized by an inflammation of the kidneys.", "url": "https://disease-ontology.org/term/DOID:10952", "evidence": [ { "id": "10952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10952" } ], "weight": 0.0 }, { "disease_id": "DOID:11049", "name": "meconium aspiration syndrome", "description": "A lung disease that is characterized by a newborn breathing in a mixture of meconium and amniotic fluid into the lungs around the time of delivery.", "url": "https://disease-ontology.org/term/DOID:11049", "evidence": [ { "id": "11049", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11049" } ], "weight": 0.0 }, { "disease_id": "DOID:11111", "name": "hydronephrosis", "description": "An urinary system disease that is characterized by swelling of one or both kidneys due to incomplete voiding of urine.", "url": "https://disease-ontology.org/term/DOID:11111", "evidence": [ { "id": "11111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11111" } ], "weight": 0.0 }, { "disease_id": "DOID:11123", "name": "IgA vasculitis", "description": "A hypersensitivity vasculitis that is characterized by purpura (purplish plaques), arthralgia, gastrointestinal upset, and/or glomerulonephritis, and may be related to increased immune response following an infection.", "url": "https://disease-ontology.org/term/DOID:11123", "evidence": [ { "id": "11123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11123" } ], "weight": 0.0 }, { "disease_id": "DOID:11247", "name": "disseminated intravascular coagulation", "description": "", "url": "https://disease-ontology.org/term/DOID:11247", "evidence": [ { "id": "11247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11247" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:11396", "name": "pulmonary edema", "description": "A respiratory failure that is characterized by the accumulation of fluid in the lung tissues causing disturbance of the gas exchange that may lead to respiratory failure.", "url": "https://disease-ontology.org/term/DOID:11396", "evidence": [ { "id": "11396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11396" } ], "weight": 0.0 }, { "disease_id": "DOID:11446", "name": "sciatic neuropathy", "description": "", "url": "https://disease-ontology.org/term/DOID:11446", "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ], "weight": 0.0 }, { "disease_id": "DOID:11716", "name": "prediabetes syndrome", "description": "A glucose metabolism disease that is characterized by blood glucose levels are high, but not high enough to be classified as type 2 diabetes.", "url": "https://disease-ontology.org/term/DOID:11716", "evidence": [ { "id": "11716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11716" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:11949", "name": "Creutzfeldt-Jakob disease", "description": "", "url": "https://disease-ontology.org/term/DOID:11949", "evidence": [ { "id": "11949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11949" } ], "weight": 0.0 }, { "disease_id": "DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.", "url": "https://disease-ontology.org/term/DOID:11984", "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ], "weight": 0.0 }, { "disease_id": "DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods.", "url": "https://disease-ontology.org/term/DOID:1205", "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ], "weight": 0.0 }, { "disease_id": "DOID:12185", "name": "otosclerosis", "description": "An otitis interna characterized by isolated endochondral bone sclerosis of the labyrinthine capsule.", "url": "https://disease-ontology.org/term/DOID:12185", "evidence": [ { "id": "12185", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12185" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12351", "name": "alcoholic hepatitis", "description": "", "url": "https://disease-ontology.org/term/DOID:12351", "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:13025", "name": "retinopathy of prematurity", "description": "", "url": "https://disease-ontology.org/term/DOID:13025", "evidence": [ { "id": "13025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13025" } ], "weight": 0.0 }, { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 }, { "disease_id": "DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid.", "url": "https://disease-ontology.org/term/DOID:13141", "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ], "weight": 0.0 }, { "disease_id": "DOID:13372", "name": "alpha 1-antitrypsin deficiency", "description": "A plasma protein metabolism disease that has_material_basis_in defective production of the protease inhibitor alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells.", "url": "https://disease-ontology.org/term/DOID:13372", "evidence": [ { "id": "13372", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13372" } ], "weight": 0.0 }, { "disease_id": "DOID:13884", "name": "sick sinus syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:13884", "evidence": [ { "id": "13884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13884" } ], "weight": 0.0 }, { "disease_id": "DOID:14115", "name": "toxic shock syndrome", "description": "A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.", "url": "https://disease-ontology.org/term/DOID:14115", "evidence": [ { "id": "14115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14115" } ], "weight": 0.0 }, { "disease_id": "DOID:14499", "name": "Fabry disease", "description": "A sphingolipidosis that is characterized by the buildup of globotriaosylceramide in the body's cells and has_material_basis_in X-linked inherited mutations in the GLA gene, encoding alpha-galactosidase A, on chromosome Xq22.", "url": "https://disease-ontology.org/term/DOID:14499", "evidence": [ { "id": "14499", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14499" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1580", "name": "diffuse scleroderma", "description": "", "url": "https://disease-ontology.org/term/DOID:1580", "evidence": [ { "id": "1580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1580" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1875", "name": "impotence", "description": "A sexual dysfunction that is characterized by persistent or recurrent inability to achieve or to maintain an erection during sexual activity.", "url": "https://disease-ontology.org/term/DOID:1875", "evidence": [ { "id": "1875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1875" } ], "weight": 0.0 }, { "disease_id": "DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries.", "url": "https://disease-ontology.org/term/DOID:1936", "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ], "weight": 0.0 }, { "disease_id": "DOID:2018", "name": "hyperinsulinism", "description": "", "url": "https://disease-ontology.org/term/DOID:2018", "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries.", "url": "https://disease-ontology.org/term/DOID:2349", "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ], "weight": 0.0 }, { "disease_id": "DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.", "url": "https://disease-ontology.org/term/DOID:2377", "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ], "weight": 0.0 }, { "disease_id": "DOID:2450", "name": "central retinal vein occlusion", "description": "", "url": "https://disease-ontology.org/term/DOID:2450", "evidence": [ { "id": "2450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2450" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:2913", "name": "acute pancreatitis", "description": "A pancreatitis that is characterized by inflammation of the pancreas over a short period of time and has symptoms of severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock.", "url": "https://disease-ontology.org/term/DOID:2913", "evidence": [ { "id": "2913", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2913" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia.", "url": "https://disease-ontology.org/term/DOID:2945", "evidence": [ { "id": "2945", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2945" } ], "weight": 0.0 }, { "disease_id": "DOID:2986", "name": "IgA glomerulonephritis", "description": "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus.", "url": "https://disease-ontology.org/term/DOID:2986", "evidence": [ { "id": "2986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2986" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3407", "name": "carotid artery disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3407", "evidence": [ { "id": "3407", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3407" } ], "weight": 0.0 }, { "disease_id": "DOID:3525", "name": "middle cerebral artery infarction", "description": "", "url": "https://disease-ontology.org/term/DOID:3525", "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ], "weight": 0.0 }, { "disease_id": "DOID:3587", "name": "pancreatic ductal carcinoma", "description": "A pancreatic carcinoma located_in the pancreatic duct.", "url": "https://disease-ontology.org/term/DOID:3587", "evidence": [ { "id": "3587", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3587" } ], "weight": 0.0 }, { "disease_id": "DOID:3755", "name": "antithrombin III deficiency", "description": "A thrombophilia that is characterized by the tendency to form clots in the veins.", "url": "https://disease-ontology.org/term/DOID:3755", "evidence": [ { "id": "3755", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3755" } ], "weight": 0.0 }, { "disease_id": "DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes.", "url": "https://disease-ontology.org/term/DOID:3770", "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:409", "name": "liver disease", "description": "", "url": "https://disease-ontology.org/term/DOID:409", "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ], "weight": 0.0 }, { "disease_id": "DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.", "url": "https://disease-ontology.org/term/DOID:418", "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:4780", "name": "anti-basement membrane glomerulonephritis", "description": "A Goodpasture syndrome that is characterized by damage to only kidney capillaries.", "url": "https://disease-ontology.org/term/DOID:4780", "evidence": [ { "id": "4780", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4780" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 }, { "disease_id": "DOID:6713", "name": "cerebrovascular disease", "description": "An vascular disease that is characterized by dysfunction of the blood vessels supplying the brain.", "url": "https://disease-ontology.org/term/DOID:6713", "evidence": [ { "id": "6713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6713" } ], "weight": 0.0 }, { "disease_id": "DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint.", "url": "https://disease-ontology.org/term/DOID:8398", "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:865", "name": "vasculitis", "description": "A vascular disease that is characterized by inflammation of the blood vessels.", "url": "https://disease-ontology.org/term/DOID:865", "evidence": [ { "id": "865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:865" } ], "weight": 0.0 }, { "disease_id": "DOID:8805", "name": "intermediate coronary syndrome", "description": "", "url": "https://disease-ontology.org/term/DOID:8805", "evidence": [ { "id": "8805", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8805" } ], "weight": 0.0 }, { "disease_id": "DOID:8923", "name": "skin melanoma", "description": "A skin cancer that has_material_basis_in melanocytes.", "url": "https://disease-ontology.org/term/DOID:8923", "evidence": [ { "id": "8923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8923" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9675", "name": "pulmonary emphysema", "description": "A chronic obstructive pulmonary disease that is characterized by permanent enlargement of air spaces distal to the terminal bronchioles and the destruction of the alveolar walls.", "url": "https://disease-ontology.org/term/DOID:9675", "evidence": [ { "id": "9675", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9675" } ], "weight": 0.0 }, { "disease_id": "DOID:988", "name": "mitral valve prolapse", "description": "A mitral valve disease where one or both of the cusps of the mitral valve bulge or collapse backward in the left atrium during systole.", "url": "https://disease-ontology.org/term/DOID:988", "evidence": [ { "id": "988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:988" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of proteolysis", "id": "GO:0045861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045861", "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q0E8V6", "url": "https://www.uniprot.org/uniprotkb/Q0E8V6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0E9B1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0E9B1", "url": "https://www.uniprot.org/uniprotkb/Q0E9B1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21484.0, "gene_names": "CR33632;CG33632;CR33632;Dmel\\CG33632;Dmel_CG33632", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0KI05-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4842, "chemical_mass": 553527.0, "gene_names": "Dmel\\CG3339;CG3339;DHC5;Dmel\\CG3339;Dmel_CG3339", "protein_name": "", "disease": [ { "disease_id": "DOID:0050144", "name": "Kartagener syndrome", "description": "A primary ciliary dyskinesia that is characterized by sinusitis, bronchiectasis and situs inversus with dextrocardia resulting from dysfunction of the cilia during embryologic development.", "url": "https://disease-ontology.org/term/DOID:0050144", "evidence": [ { "id": "0050144", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050144" } ], "weight": 0.0 }, { "disease_id": "DOID:0110605", "name": "primary ciliary dyskinesia 7", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with chronic respiratory infections, chronic sinusitis, recurrent bronchitis, and pneumonia beginning in infancy or early childhood and has_material_basis_in mutation in the DNAH11 gene on chromosome 7p21.", "url": "https://disease-ontology.org/term/DOID:0110605", "evidence": [ { "id": "0110605", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110605" } ], "weight": 0.0 }, { "disease_id": "DOID:0111853", "name": "primary ciliary dyskinesia 40", "description": "A primary ciliary dyskinesia characterized by a subtle defect in the bend of the distal portion of the cilia, reduced ciliary clearance in-vitro, relatively mild respiratory phenotype and laterality defects in all reported patients that has_material_basis_in homozygous or compound heterozygous mutation in the DNAH9 gene on chromosome 17p12.", "url": "https://disease-ontology.org/term/DOID:0111853", "evidence": [ { "id": "0111853", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111853" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cilium movement involved in cell motility", "id": "GO:0060294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060294", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "minus-end-directed microtubule motor activity", "id": "GO:0008569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008569", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "outer dynein arm", "id": "GO:0036157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036157", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "Q0KI05", "url": "https://www.uniprot.org/uniprotkb/Q0KI05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q0KI05-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0KI25-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1125, "chemical_mass": 126543.0, "gene_names": "CG13825;Dmel\\CG4467;CG13825;CG4467;Dmel\\CG4467;Dmel_CG4467", "protein_name": "Endoplasmic reticulum aminopeptidase 2", "disease": [ { "disease_id": "DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells.", "url": "https://disease-ontology.org/term/DOID:127", "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ], "weight": 0.0 }, { "disease_id": "DOID:13129", "name": "severe pre-eclampsia", "description": "A pre-eclampsia that has_symptom at least one of the following: SBP of 160mm HG or higher or DPB of 110mm HG or higher on 2 occasions at least 6 hours apart, proteinuria more than 5g in a 24-hour collection, pulmonary edema or cyanosis, oliguria, persistent headaches, epigastric pain and/or impaired liver function, thrombocytopenia, oligohydramnios, decreased fetal growth or placental abruption.", "url": "https://disease-ontology.org/term/DOID:13129", "evidence": [ { "id": "13129", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13129" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2871", "name": "endometrial carcinoma", "description": "A endometrial cancer that is located_in the tissue lining the uterus.", "url": "https://disease-ontology.org/term/DOID:2871", "evidence": [ { "id": "2871", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2871" } ], "weight": 0.0 }, { "disease_id": "DOID:2893", "name": "cervix carcinoma", "description": "A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.", "url": "https://disease-ontology.org/term/DOID:2893", "evidence": [ { "id": "2893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2893" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:8488", "name": "polyhydramnios", "description": "A placenta disease that is characterized by an excess of amniotic fluid in the amniotic sac.", "url": "https://disease-ontology.org/term/DOID:8488", "evidence": [ { "id": "8488", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8488" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q0KI25", "url": "https://www.uniprot.org/uniprotkb/Q0KI25" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0KI77-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 388, "chemical_mass": 43792.0, "gene_names": "Dmel\\CG11598;CG11598;Dmel\\CG11598;Dmel_CG11598", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 } ], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q0KI77", "url": "https://www.uniprot.org/uniprotkb/Q0KI77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q0KI91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q0KI91", "url": "https://www.uniprot.org/uniprotkb/Q0KI91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 171, "chemical_mass": 19937.0, "gene_names": "Dmel\\CG12817;BcDNA:RE53107;CG12817;Dmel\\CG12817;Dmel_CG12817", "protein_name": "EF-hand domain-containing protein", "disease": [], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q0KI91", "url": "https://www.uniprot.org/uniprotkb/Q0KI91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q2MGK5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGK5", "url": "https://www.uniprot.org/uniprotkb/Q2MGK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 690, "chemical_mass": 79235.0, "gene_names": "Dmel\\CG4970;CG32953;CG4970;Dmel\\CG4970;Dmel_CG4970;anon-WO0140519.184", "protein_name": "CCDC113/CCDC96 coiled-coil domain-containing protein", "disease": [], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK5", "url": "https://www.uniprot.org/uniprotkb/Q2MGK5" } ], "pmid": "" } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK5", "url": "https://www.uniprot.org/uniprotkb/Q2MGK5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK5", "url": "https://www.uniprot.org/uniprotkb/Q2MGK5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q2MGK5-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 107, "start_aa": "Ser", "end_pos": 107, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser107", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q2MGK5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q2MGK5" } ] } ] }, { "uniprot_canonical_ac": "Q2MGK5-1", "start_pos": "406", "end_pos": "406", "site_lbl": "Thr406", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 406, "start_aa": "Thr", "end_pos": 406, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr406", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q2MGL5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGL5", "url": "https://www.uniprot.org/uniprotkb/Q2MGL5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21422.0, "gene_names": "Dmel\\CG33764;CG33764;Dmel\\CG33764;Dmel_CG33764", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q2MGL8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 310, "chemical_mass": 35801.0, "gene_names": "Dmel\\CG33966;CG1211;CG33966;Dmel\\CG33966;Dmel_CG33966", "protein_name": "CRAL-TRIO domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "pmid": "" }, { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "pmid": "" } ], "cellular_component": [ { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "pmid": "" } ], "biological_process": [ { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "Q2MGL8", "url": "https://www.uniprot.org/uniprotkb/Q2MGL8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q2MGP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGP2", "url": "https://www.uniprot.org/uniprotkb/Q2MGP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 160, "chemical_mass": 18734.0, "gene_names": "Dmel\\CG33665;CG33665;Dmel\\CG33665;Dmel_CG33665", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q2MGP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2MGP7", "url": "https://www.uniprot.org/uniprotkb/Q2MGP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 160, "chemical_mass": 18712.0, "gene_names": "Dmel\\CG33664;CG33664;Dmel\\CG33664;Dmel_CG33664", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q2PE06-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PE06", "url": "https://www.uniprot.org/uniprotkb/Q2PE06" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 325, "chemical_mass": 37660.0, "gene_names": "Dmel\\CG34025;BP1082;CG34025;Dmel\\CG34025;Dmel_CG34025;HDC08169", "protein_name": "F-box domain-containing protein", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q2PE06", "url": "https://www.uniprot.org/uniprotkb/Q2PE06" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q2PE06", "url": "https://www.uniprot.org/uniprotkb/Q2PE06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q2PE19-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q2PE19", "url": "https://www.uniprot.org/uniprotkb/Q2PE19" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 281, "chemical_mass": 30356.0, "gene_names": "BP1015;BP1015;CG34040;Dmel\\CG34040;Dmel_CG34040", "protein_name": "DUF753 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q2PE19-1", "start_pos": "208", "end_pos": "208", "site_lbl": "Thr208", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4AB27-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1288, "chemical_mass": 148074.0, "gene_names": "Myo95E;95E;CG31134;CG31135;CG5501;Dm95E;DmAE003746;Dmel\\CG5501;Dmel_CG5501;Myo5;Myo95E;myo 95E", "protein_name": "", "disease": [ { "disease_id": "DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem.", "url": "https://disease-ontology.org/term/DOID:10003", "evidence": [ { "id": "10003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" } ], "cellular_component": [ { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" }, { "name": "actin filament-based movement", "id": "GO:0030048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030048", "evidence": [ { "database": "UniProtKB", "id": "Q4AB27", "url": "https://www.uniprot.org/uniprotkb/Q4AB27" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q4AB27-1", "start_pos": "374", "end_pos": "374", "site_lbl": "Thr374", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 374, "start_aa": "Thr", "end_pos": 374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr374", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABD8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 256, "chemical_mass": 26360.0, "gene_names": "His1:CG33807;CG33807;Dmel\\CG33807;Dmel_CG33807;His1:CG33807", "protein_name": "", "disease": [ { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" } ], "molecular_function": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "nucleosomal DNA binding", "id": "GO:0031492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031492", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "chromosome condensation", "id": "GO:0030261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" }, { "name": "negative regulation of DNA recombination", "id": "GO:0045910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045910", "evidence": [ { "database": "UniProtKB", "id": "Q4ABD8", "url": "https://www.uniprot.org/uniprotkb/Q4ABD8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q4ABD8-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Thr43", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 43, "start_aa": "Thr", "end_pos": 43, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr43", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABF1", "url": "https://www.uniprot.org/uniprotkb/Q4ABF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21164.0, "gene_names": "Dmel\\CG33928;CG33928;Dmel\\CG33928;Dmel_CG33928", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABF4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABF4", "url": "https://www.uniprot.org/uniprotkb/Q4ABF4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 173, "chemical_mass": 20559.0, "gene_names": "Dmel\\CG33679;BP1003;CG33679;Dmel\\CG33679;Dmel_CG33679", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABF8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABF8", "url": "https://www.uniprot.org/uniprotkb/Q4ABF8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 20748.0, "gene_names": "Dmel\\CG33643;CG33643;Dmel\\CG33643;Dmel_CG33643", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABG8", "url": "https://www.uniprot.org/uniprotkb/Q4ABG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 180, "chemical_mass": 21314.0, "gene_names": "Dmel\\CG33723;CG33723;Dmel\\CG33723;Dmel_CG33723", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABH5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABH5", "url": "https://www.uniprot.org/uniprotkb/Q4ABH5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 20608.0, "gene_names": "Dmel\\CG33771;CG14458;CG33771;Dmel\\CG33771;Dmel_CG33771", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABJ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABJ1", "url": "https://www.uniprot.org/uniprotkb/Q4ABJ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 21260.0, "gene_names": "Dmel\\CG33689;CG33689;Dmel\\CG33689;Dmel_CG33689", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABJ4", "url": "https://www.uniprot.org/uniprotkb/Q4ABJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 178, "chemical_mass": 21341.0, "gene_names": "Dmel\\CG33795;CG33795;Dmel\\CG33795;Dmel_CG33795", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q4ABK1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q4ABK1", "url": "https://www.uniprot.org/uniprotkb/Q4ABK1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 172, "chemical_mass": 20251.0, "gene_names": "Dmel\\CG33777;CG33777;Dmel\\CG33777;Dmel_CG33777", "protein_name": "MD-2-related lipid-recognition domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IP19-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1081, "chemical_mass": 113665.0, "gene_names": "dac;BG:DS02780.3;CG4952;DAC;Dac2-3;Dachshund;Dach;Dac;Dm-DAC;Dmel\\CG4952;Dmel_CG4952;dach;dac;l(2)36Ae;l(2)rK364;spn", "protein_name": "", "disease": [], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "leg disc proximal/distal pattern formation", "id": "GO:0007479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007479", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "genital disc morphogenesis", "id": "GO:0007483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007483", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "spermathecum morphogenesis", "id": "GO:0035211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035211", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "genital disc development", "id": "GO:0035215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035215", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "genital disc sexually dimorphic development", "id": "GO:0035263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035263", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "compound eye photoreceptor development", "id": "GO:0042051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042051", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "photoreceptor cell fate specification", "id": "GO:0043704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043704", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "antennal joint development", "id": "GO:0048098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048098", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q8IP19", "url": "https://www.uniprot.org/uniprotkb/Q8IP19" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IP19-1", "start_pos": "706", "end_pos": "706", "site_lbl": "Thr706", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 706, "start_aa": "Thr", "end_pos": 706, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr706", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q59E04-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 276, "chemical_mass": 29995.0, "gene_names": "7B2;7B2;CG1168;Dmel\\CG1168;FBgn0040073;d7B2", "protein_name": "Neuroendocrine protein 7B2", "disease": [ { "disease_id": "DOID:3946", "name": "pituitary-dependent Cushing's disease", "description": "", "url": "https://disease-ontology.org/term/DOID:3946", "evidence": [ { "id": "3946", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3946" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" } ], "biological_process": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" }, { "name": "regulation of hormone secretion", "id": "GO:0046883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046883", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" }, { "name": "positive regulation of proteolysis", "id": "GO:0045862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045862", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" } ], "molecular_function": [ { "name": "peptidase activator activity", "id": "GO:0016504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016504", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "Q59E04", "url": "https://www.uniprot.org/uniprotkb/Q59E04" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q59E05-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 337, "chemical_mass": 39178.0, "gene_names": "Dmel\\CG14667;CG14667;Dmel\\CG14667;Dmel_CG14667", "protein_name": "Transcription factor Ouib", "disease": [], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q59E05", "url": "https://www.uniprot.org/uniprotkb/Q59E05" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q76NR6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 319, "chemical_mass": 35360.0, "gene_names": "regucalcin;CG1803;Dmel\\CG1803;Dmel_CG1803;Regucalcin;RgN;T1;regucalcin", "protein_name": "Regucalcin", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "L-ascorbic acid biosynthetic process", "id": "GO:0019853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019853", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" } ], "molecular_function": [ { "name": "gluconolactonase activity", "id": "GO:0004341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004341", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q76NR6", "url": "https://www.uniprot.org/uniprotkb/Q76NR6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KS21-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KS21", "url": "https://www.uniprot.org/uniprotkb/Q7KS21" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 219, "chemical_mass": 24439.0, "gene_names": "Dmel\\CG33342;BP1089;CG33342;Dmel\\CG33342;Dmel_CG33342;mdcds_42691", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KSA2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KSA2", "url": "https://www.uniprot.org/uniprotkb/Q7KSA2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 394, "chemical_mass": 44210.0, "gene_names": "Dmel\\CG31223;CG15694;CG31223;Dmel_CG31223", "protein_name": "HIT-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KSA2", "url": "https://www.uniprot.org/uniprotkb/Q7KSA2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KSA2-1", "start_pos": "191", "end_pos": "191", "site_lbl": "Thr191", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 191, "start_aa": "Thr", "end_pos": 191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr191", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDS9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1363, "chemical_mass": 155497.0, "gene_names": "Ask1;ASK1;Ask1;Ask;CG4720;D-ASK;DASK1;DASK;DPk92B/ASK1;Dmel\\CG4720;Dmel_CG4720;MEKK5/ASK1;Pk92B;ask1;dASK1;dASK;dAsk1;pk92B", "protein_name": "", "disease": [ { "disease_id": "DOID:10976", "name": "membranous glomerulonephritis", "description": "", "url": "https://disease-ontology.org/term/DOID:10976", "evidence": [ { "id": "10976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10976" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 }, { "disease_id": "DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.", "url": "https://disease-ontology.org/term/DOID:3526", "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ], "weight": 0.0 }, { "disease_id": "DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia.", "url": "https://disease-ontology.org/term/DOID:5844", "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ], "weight": 0.0 }, { "disease_id": "DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:670", "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ], "weight": 0.0 }, { "disease_id": "DOID:8677", "name": "perinatal necrotizing enterocolitis", "description": "", "url": "https://disease-ontology.org/term/DOID:8677", "evidence": [ { "id": "8677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8677" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "MAP kinase kinase kinase activity", "id": "GO:0004709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004709", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" } ], "biological_process": [ { "name": "MAPK cascade", "id": "GO:0000165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000165", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" }, { "name": "regulation of adult chitin-containing cuticle pigmentation", "id": "GO:0048082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048082", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" } ], "cellular_component": [ { "name": "protein kinase complex", "id": "GO:1902911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902911", "evidence": [ { "database": "UniProtKB", "id": "Q9VDS9", "url": "https://www.uniprot.org/uniprotkb/Q9VDS9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDS9-1", "start_pos": "107", "end_pos": "107", "site_lbl": "Ser107", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 107, "start_aa": "Ser", "end_pos": 107, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser107", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VDS9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VDS9" } ] } ] }, { "uniprot_canonical_ac": "Q9VDS9-1", "start_pos": "1214", "end_pos": "1214", "site_lbl": "Thr1214", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1214, "start_aa": "Thr", "end_pos": 1214, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1214", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VDS9-1", "start_pos": "1344", "end_pos": "1344", "site_lbl": "Thr1344", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1344, "start_aa": "Thr", "end_pos": 1344, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1344", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VEC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEC4", "url": "https://www.uniprot.org/uniprotkb/Q9VEC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 450, "chemical_mass": 50716.0, "gene_names": "Dmel\\CG7208;CG 7208;CG7208;Dmel\\CG7208;Dmel_CG7208", "protein_name": "DUF4780 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KSK1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 516, "chemical_mass": 56620.0, "gene_names": "Sp212;CG33329;Dmel\\CG33329;Dmel_CG33329;ORE-5;SP212;Sp212", "protein_name": "", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "pmid": "" }, { "name": "response to bacterium", "id": "GO:0009617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009617", "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "pmid": "" }, { "name": "response to fungus", "id": "GO:0009620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009620", "evidence": [ { "database": "UniProtKB", "id": "Q7KSK1", "url": "https://www.uniprot.org/uniprotkb/Q7KSK1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KSK1-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KSK1-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KSK1-1", "start_pos": "250", "end_pos": "250", "site_lbl": "Thr250", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KT14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 197, "chemical_mass": 23032.0, "gene_names": "CheB38b;38E.23;CG33321;CG9329;CheB38b;Dmel\\CG33321;Dmel_CG33321", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" }, { "name": "detection of pheromone", "id": "GO:0043695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043695", "evidence": [ { "database": "UniProtKB", "id": "Q7KT14", "url": "https://www.uniprot.org/uniprotkb/Q7KT14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KT22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1292, "chemical_mass": 145261.0, "gene_names": "Dme_CG9270;CG9270;DmCG9270;Dme_CG9270;Dmel\\CG9270;Dmel_CG9270", "protein_name": "", "disease": [ { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q7KT22", "url": "https://www.uniprot.org/uniprotkb/Q7KT22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KT60-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT60", "url": "https://www.uniprot.org/uniprotkb/Q7KT60" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2353, "chemical_mass": 268823.0, "gene_names": "anon-WO03042407.98;BG:DS02740.18;CG31817;DS02740.18;Dmel\\CG31817;Dmel_CG31817;anon-WO03042407.98;anon-WO03042407.99", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KT77-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 876, "chemical_mass": 100981.0, "gene_names": "Dmel\\CG33310;BG:DS00929.6;CG15274;CG33310;Dmel\\CG33310;Dmel_CG33310;NaKbeta", "protein_name": "", "disease": [], "biological_process": [ { "name": "intracellular sodium ion homeostasis", "id": "GO:0006883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006883", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" }, { "name": "intracellular potassium ion homeostasis", "id": "GO:0030007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030007", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" }, { "name": "sodium ion export across plasma membrane", "id": "GO:0036376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036376", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" }, { "name": "potassium ion import across plasma membrane", "id": "GO:1990573", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990573", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" } ], "cellular_component": [ { "name": "sodium:potassium-exchanging ATPase complex", "id": "GO:0005890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005890", "evidence": [ { "database": "UniProtKB", "id": "Q7KT77", "url": "https://www.uniprot.org/uniprotkb/Q7KT77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KTG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4333, "chemical_mass": 494320.0, "gene_names": "Apoltp;ApoLTPII;ApoLTPI;ApoLTP;Apoltp;CG15828;CT39214;Dmel\\CG15828;Dmel_CG15828;LTP;Ltp;apoLTP;apoltp;ltp", "protein_name": "", "disease": [ { "disease_id": "DOID:0111061", "name": "familial hypobetalipoproteinemia 2", "description": "A hypobetalipoproteinemia that has_material_basis_in homozygous or compound heterozygous mutation in the ANGPTL3 gene on chromosome 1p31.", "url": "https://disease-ontology.org/term/DOID:0111061", "evidence": [ { "id": "0111061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111061" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.", "url": "https://disease-ontology.org/term/DOID:9452", "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of lipid transport", "id": "GO:0032370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032370", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "sterol transport", "id": "GO:0015918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015918", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "transport across blood-brain barrier", "id": "GO:0150104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150104", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "acylglycerol transport", "id": "GO:0034196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034196", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "lipoprotein particle receptor binding", "id": "GO:0070325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070325", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "nutrient reservoir activity", "id": "GO:0045735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045735", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" }, { "name": "basal part of cell", "id": "GO:0045178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045178", "evidence": [ { "database": "UniProtKB", "id": "Q7KTG2", "url": "https://www.uniprot.org/uniprotkb/Q7KTG2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KTH6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTH6", "url": "https://www.uniprot.org/uniprotkb/Q7KTH6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 689, "chemical_mass": 79664.0, "gene_names": "CG13394;CG13394;CG42820;Dmel\\CG42820;Dmel_CG42820", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KTJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 264, "chemical_mass": 29678.0, "gene_names": "Dmel\\CG8349;CG8349;Dmel\\CG8349;Dmel_CG8349", "protein_name": "cytidine deaminase", "disease": [ { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "cytidine deaminase activity", "id": "GO:0004126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004126", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleobase-containing small molecule metabolic process", "id": "GO:0055086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055086", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" }, { "name": "pyrimidine-containing compound metabolic process", "id": "GO:0072527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072527", "evidence": [ { "database": "UniProtKB", "id": "Q7KTJ2", "url": "https://www.uniprot.org/uniprotkb/Q7KTJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KTJ2-1", "start_pos": "169", "end_pos": "169", "site_lbl": "Thr169", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 169, "start_aa": "Thr", "end_pos": 169, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr169", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VM74-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 715, "chemical_mass": 77438.0, "gene_names": "Nha1;CG10806;DmNHA1;Dmel\\CG10806;Dmel_CG10806;NHA1;Nha1;nha1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" }, { "name": "chloride transmembrane transporter activity", "id": "GO:0015108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015108", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" } ], "biological_process": [ { "name": "renal sodium ion transport", "id": "GO:0003096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003096", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "Q9VM74", "url": "https://www.uniprot.org/uniprotkb/Q9VM74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VM74-1", "start_pos": "39", "end_pos": "39", "site_lbl": "Thr39", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KUG3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUG3", "url": "https://www.uniprot.org/uniprotkb/Q7KUG3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 88, "chemical_mass": 9680.0, "gene_names": "CG6100;CG14139;CG32084;CG33270;CG6100;Dmel\\CG33270;Dmel_CG33270;FBgn0053270", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KUI9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUI9", "url": "https://www.uniprot.org/uniprotkb/Q7KUI9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 208, "chemical_mass": 24044.0, "gene_names": "Dmel\\CG33262;CG33262;Dmel\\CG33262;Dmel_CG33262", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KUV8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KUV8", "url": "https://www.uniprot.org/uniprotkb/Q7KUV8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 305, "chemical_mass": 34985.0, "gene_names": "Dmel\\CG6023;CG6023;Dmel\\CG6023;Dmel_CG6023", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KV35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KV35", "url": "https://www.uniprot.org/uniprotkb/Q7KV35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1584, "chemical_mass": 174342.0, "gene_names": "Dmel\\CG33235;CG15192;CG33235;Dmel\\CG33235;Dmel_CG33235", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q7KV35-1", "start_pos": "1383", "end_pos": "1383", "site_lbl": "Thr1383", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1383, "start_aa": "Thr", "end_pos": 1383, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1383", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q7KV35-1", "start_pos": "163", "end_pos": "163", "site_lbl": "Thr163", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 163, "start_aa": "Thr", "end_pos": 163, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr163", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q7KV35", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q7KV35" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7KVP9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 769, "chemical_mass": 88011.0, "gene_names": "Xpd;CG9433;DhR3;DhXPD;DmXPD;Dmel\\CG9433;Dmel_CG9433;ERCC2;XPD/ERCC2;XPD;Xpd;l(2)SH2 2137;l(2)SH2137;xpd", "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "disease": [ { "disease_id": "DOID:0050427", "name": "xeroderma pigmentosum", "description": "A syndrome that is characterized by a deficiency in the ability to repair ultraviolet damage that has_material_basis_in autosomal recessive inheritance of DNA repair.", "url": "https://disease-ontology.org/term/DOID:0050427", "evidence": [ { "id": "0050427", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050427" } ], "weight": 0.0 }, { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:0060655", "name": "autosomal recessive congenital ichthyosis", "description": "An ichthyosis that is characterized by autosomal recessive inheritance and abnormal skin scaling over the whole body due to a defect in keratinization.", "url": "https://disease-ontology.org/term/DOID:0060655", "evidence": [ { "id": "0060655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060655" } ], "weight": 0.0 }, { "disease_id": "DOID:0080912", "name": "cerebrooculofacioskeletal syndrome 2", "description": "A cerebrooculofacioskeletal syndrome that has_material_basis_in compound heterozygous mutation in the DNA repair gene XPD (ERCC2) on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0080912", "evidence": [ { "id": "0080912", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080912" } ], "weight": 0.0 }, { "disease_id": "DOID:0110845", "name": "xeroderma pigmentosum group D", "description": "A xeroderma pigmentosum that has_material_basis_in homozygous or compound heterozygous mutation in the excision repair gene ERCC2 on chromosome 19q13.", "url": "https://disease-ontology.org/term/DOID:0110845", "evidence": [ { "id": "0110845", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110845" } ], "weight": 0.0 }, { "disease_id": "DOID:0111873", "name": "photosensitive trichothiodystrophy 1", "description": "A photosensitive trichothiodystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the ERCC2 gene on chromosome 19q13.32.", "url": "https://disease-ontology.org/term/DOID:0111873", "evidence": [ { "id": "0111873", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111873" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach.", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder.", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ], "weight": 0.0 }, { "disease_id": "DOID:11088", "name": "asphyxia neonatorum", "description": "A respiratory system disease that is characterized by deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain.", "url": "https://disease-ontology.org/term/DOID:11088", "evidence": [ { "id": "11088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11088" } ], "weight": 0.0 }, { "disease_id": "DOID:12689", "name": "acoustic neuroma", "description": "", "url": "https://disease-ontology.org/term/DOID:12689", "evidence": [ { "id": "12689", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12689" } ], "weight": 0.0 }, { "disease_id": "DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability.", "url": "https://disease-ontology.org/term/DOID:14250", "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye.", "url": "https://disease-ontology.org/term/DOID:1909", "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ], "weight": 0.0 }, { "disease_id": "DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium.", "url": "https://disease-ontology.org/term/DOID:2152", "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ], "weight": 0.0 }, { "disease_id": "DOID:2960", "name": "photosensitive trichothiodystrophy", "description": "A trichothiodystrophy characterized by skin that is extremely sensitive to ultraviolet (UV) rays from sunlight.", "url": "https://disease-ontology.org/term/DOID:2960", "evidence": [ { "id": "2960", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2960" } ], "weight": 0.0 }, { "disease_id": "DOID:2962", "name": "Cockayne syndrome", "description": "A syndrome that is characterized by an abnormally small head size (microcephaly), a failure to gain weight and grow at the expected rate (failure to thrive) leading to very short stature, and delayed development.", "url": "https://disease-ontology.org/term/DOID:2962", "evidence": [ { "id": "2962", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2962" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:37", "name": "skin disease", "description": "An integumentary system disease that is located_in skin.", "url": "https://disease-ontology.org/term/DOID:37", "evidence": [ { "id": "37", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:37" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 }, { "disease_id": "DOID:635", "name": "acquired immunodeficiency syndrome", "description": "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.", "url": "https://disease-ontology.org/term/DOID:635", "evidence": [ { "id": "635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:635" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 }, { "disease_id": "DOID:9655", "name": "oral mucosa leukoplakia", "description": "A mouth disease that is characterized by a white patch or plaque that develops in the oral cavity and is strongly associated with smoking.", "url": "https://disease-ontology.org/term/DOID:9655", "evidence": [ { "id": "9655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9655" } ], "weight": 0.0 }, { "disease_id": "DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging.", "url": "https://disease-ontology.org/term/DOID:9669", "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "5'-3' DNA helicase activity", "id": "GO:0043139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043139", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription factor TFIIH holo complex", "id": "GO:0005675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005675", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription factor TFIIH core complex", "id": "GO:0000439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000439", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "polytene chromosome puff", "id": "GO:0005703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005703", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "polytene chromosome interband", "id": "GO:0005705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005705", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "response to UV", "id": "GO:0009411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009411", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "negative regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010972", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "RNA polymerase II promoter clearance", "id": "GO:0001111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001111", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "transcription open complex formation at RNA polymerase II promoter", "id": "GO:0001113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001113", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "regulation of chromosome segregation", "id": "GO:0051983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051983", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "hair cell differentiation", "id": "GO:0035315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035315", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "positive regulation of mitotic recombination", "id": "GO:0045951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045951", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" }, { "name": "regulation of syncytial blastoderm mitotic cell cycle", "id": "GO:0007348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007348", "evidence": [ { "database": "UniProtKB", "id": "Q7KVP9", "url": "https://www.uniprot.org/uniprotkb/Q7KVP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7PLB8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2394, "chemical_mass": 266851.0, "gene_names": "FASN3;80Ff;CG17374;DM_7289423;Dmel\\CG17374;Dmel_CG17374;FASN3;FASN[CG17374];FAS[CG17374];FAS;fasn3;l(3)80Ff;l(3)Lh4B;l4B", "protein_name": "Fatty acid synthase", "disease": [ { "disease_id": "DOID:0080000", "name": "muscular disease", "description": "A musculoskeletal system disease that affects the muscles.", "url": "https://disease-ontology.org/term/DOID:0080000", "evidence": [ { "id": "0080000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080000" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "biological_process": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphopantetheine binding", "id": "GO:0031177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031177", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "fatty acid synthase activity", "id": "GO:0004312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004312", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "[acyl-carrier-protein] S-acetyltransferase activity", "id": "GO:0004313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004313", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "3-oxoacyl-[acyl-carrier-protein] synthase activity", "id": "GO:0004315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004315", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0004316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004316", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "fatty acyl-[ACP] hydrolase activity", "id": "GO:0016297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016297", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity", "id": "GO:0019171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019171", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" }, { "name": "enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "id": "GO:0141148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141148", "evidence": [ { "database": "UniProtKB", "id": "Q7PLB8", "url": "https://www.uniprot.org/uniprotkb/Q7PLB8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q7PLI0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 781, "chemical_mass": 86823.0, "gene_names": "p120ctn;CG17484;Dmel\\CG17484;Dmel_CG17484;Dp120[ctn];Dp120ctn;P120-catenin;P120ctn;P120;dP120ctn;dp120ctn;p120[ctn];p120ctn;p120", "protein_name": "", "disease": [ { "disease_id": "DOID:0050431", "name": "arrhythmogenic right ventricular cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle and limited or no involvement of the left ventricle.", "url": "https://disease-ontology.org/term/DOID:0050431", "evidence": [ { "id": "0050431", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050431" } ], "weight": 0.0 }, { "disease_id": "DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells.", "url": "https://disease-ontology.org/term/DOID:0050866", "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0080346", "name": "blepharocheilodontic syndrome 2", "description": "A blepharocheilodontic syndrome that has_material_basis_in heterozygous mutation in the CTNND1 gene on chromosome 11q12.", "url": "https://disease-ontology.org/term/DOID:0080346", "evidence": [ { "id": "0080346", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080346" } ], "weight": 0.0 }, { "disease_id": "DOID:0110077", "name": "arrhythmogenic right ventricular dysplasia 9", "description": "An arrhythmogenic right ventricular dysplasia that has_material_basis_in heterozygous mutations in the PKP2 gene on chromosome 12p11.", "url": "https://disease-ontology.org/term/DOID:0110077", "evidence": [ { "id": "0110077", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110077" } ], "weight": 0.0 }, { "disease_id": "DOID:11198", "name": "DiGeorge syndrome", "description": "A syndrome that has_material_basis_in a large deletion of the chromosome 22q11.2 region which includes the DGS gene needed for development of the thymus and related glands with subsequent lack of T-cell production.", "url": "https://disease-ontology.org/term/DOID:11198", "evidence": [ { "id": "11198", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11198" } ], "weight": 0.0 }, { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 }, { "disease_id": "DOID:2121", "name": "ectodermal dysplasia", "description": "A syndrome characterized by abnormal development in 2 or more ectodermal structures (hair, nails, teeth, and sweat glands) without other systemic findings.", "url": "https://disease-ontology.org/term/DOID:2121", "evidence": [ { "id": "2121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2121" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries.", "url": "https://disease-ontology.org/term/DOID:6432", "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" } ], "biological_process": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "dendritic spine morphogenesis", "id": "GO:0060997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060997", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "adherens junction maintenance", "id": "GO:0034334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034334", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" } ], "molecular_function": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "Q7PLI0", "url": "https://www.uniprot.org/uniprotkb/Q7PLI0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q86BI5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q86BI5", "url": "https://www.uniprot.org/uniprotkb/Q86BI5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 13838.0, "gene_names": "CG13057;CG13057;CG33060;Dmel\\CG33060;Dmel_CG33060", "protein_name": "Protein dpy-30 homolog", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IML0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 373, "chemical_mass": 42066.0, "gene_names": "Dmel\\CG14507;CG14507;Dmel\\CG14507;Dmel_CG14507", "protein_name": "Phospholipase A2", "disease": [ { "disease_id": "DOID:0111677", "name": "familial benign fleck retina", "description": "A retinal disease characterized by a striking pattern of diffuse, yellow-white, fleck-like lesions extending to the far periphery of the retina but with no apparent visual or electrophysiologic deficits that has_material_basis_in homozygous or compound heterozygous mutation in the PLA2G5 gene on chromosome 1p36.13.", "url": "https://disease-ontology.org/term/DOID:0111677", "evidence": [ { "id": "0111677", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111677" } ], "weight": 0.0 }, { "disease_id": "DOID:11151", "name": "cholecystolithiasis", "description": "", "url": "https://disease-ontology.org/term/DOID:11151", "evidence": [ { "id": "11151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11151" } ], "weight": 0.0 }, { "disease_id": "DOID:11204", "name": "allergic conjunctivitis", "description": "A chronic conjunctivitis that is an inflammation of the conjunctiva involing red, itchy, and watery eyes a resulting from an exposure to an allergen or an irritant.", "url": "https://disease-ontology.org/term/DOID:11204", "evidence": [ { "id": "11204", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11204" } ], "weight": 0.0 }, { "disease_id": "DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.", "url": "https://disease-ontology.org/term/DOID:11394", "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ], "weight": 0.0 }, { "disease_id": "DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.", "url": "https://disease-ontology.org/term/DOID:1596", "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:8534", "name": "gastroesophageal reflux disease", "description": "", "url": "https://disease-ontology.org/term/DOID:8534", "evidence": [ { "id": "8534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8534" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" }, { "name": "arachidonate secretion", "id": "GO:0050482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050482", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" } ], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "Q8IML0", "url": "https://www.uniprot.org/uniprotkb/Q8IML0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IMQ3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMQ3", "url": "https://www.uniprot.org/uniprotkb/Q8IMQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 988, "chemical_mass": 110326.0, "gene_names": "Dmel\\CG31077;CG31077;Dmel\\CG31077;Dmel_CG31077", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IMQ3", "url": "https://www.uniprot.org/uniprotkb/Q8IMQ3" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q8IMQ3", "url": "https://www.uniprot.org/uniprotkb/Q8IMQ3" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q8IMQ3", "url": "https://www.uniprot.org/uniprotkb/Q8IMQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IMR4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 402, "chemical_mass": 44796.0, "gene_names": "Yif1;CG5484;COP;Dmel\\CG5484;Dmel_CG5484;Yif1;anon-WO0118547.366;doc", "protein_name": "", "disease": [ { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" } ], "biological_process": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" }, { "name": "positive regulation of synapse pruning", "id": "GO:1905808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905808", "evidence": [ { "database": "UniProtKB", "id": "Q8IMR4", "url": "https://www.uniprot.org/uniprotkb/Q8IMR4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IMT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IMT4", "url": "https://www.uniprot.org/uniprotkb/Q8IMT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 428, "chemical_mass": 49978.0, "gene_names": "CG13665;CG13665;CG31288;Dmel\\CG31288;Dmel_CG31288;Dro11-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q8IMT4", "url": "https://www.uniprot.org/uniprotkb/Q8IMT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IN22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 381, "chemical_mass": 44955.0, "gene_names": "Gr93d;93F.4;CG31335;DmGr93d;Dmel\\CG31335;Dmel_CG31335;GR93F.4;GR93d;Gr93F4;Gr93d", "protein_name": "Gustatory receptor", "disease": [], "biological_process": [ { "name": "male courtship behavior", "id": "GO:0008049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008049", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "chemosensory behavior", "id": "GO:0007635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007635", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "sensory perception of taste", "id": "GO:0050909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050909", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" }, { "name": "taste receptor activity", "id": "GO:0008527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008527", "evidence": [ { "database": "UniProtKB", "id": "Q8IN22", "url": "https://www.uniprot.org/uniprotkb/Q8IN22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8ING0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 520, "chemical_mass": 57228.0, "gene_names": "CG9645;CG31326;CG9645;Dmel\\CG31326;Dmel_CG31326;SPH144;cg9645", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "pmid": "" } ], "molecular_function": [ { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "Q8ING0", "url": "https://www.uniprot.org/uniprotkb/Q8ING0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8ING1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8ING1", "url": "https://www.uniprot.org/uniprotkb/Q8ING1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 861, "chemical_mass": 98033.0, "gene_names": "Dmel\\CG31327;BcDNA:AT17065;CG31327;Dmel\\CG31327;Dmel_CG31327", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8ING1-1", "start_pos": "291", "end_pos": "291", "site_lbl": "Thr291", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 291, "start_aa": "Thr", "end_pos": 291, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr291", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8INY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8INY9", "url": "https://www.uniprot.org/uniprotkb/Q8INY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 212, "chemical_mass": 24534.0, "gene_names": "Dmel\\CG31804;CG31804;Dmel\\CG31804;Dmel_CG31804;NEST:bs12c10;NEST:bs13h04;NEST:bs27h11;NEST:bs34f07", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IP11-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 233, "chemical_mass": 26411.0, "gene_names": "Tsen2;CG31812;Dmel\\CG31812;Dmel_CG31812;TSEN2;Tsen2", "protein_name": "tRNA-intron lyase", "disease": [ { "disease_id": "DOID:0060268", "name": "pontocerebellar hypoplasia type 2B", "description": "A severe pontocerebellar hypoplasia that is characterized by progressive microcephaly, clonus, dysphagia and failure to thrive, has_material_basis_in autosomal recessive inheritance of mutation in the TSEN2 gene.", "url": "https://disease-ontology.org/term/DOID:0060268", "evidence": [ { "id": "0060268", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060268" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" }, { "name": "tRNA-intron endonuclease complex", "id": "GO:0000214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000214", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" } ], "biological_process": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" }, { "name": "tRNA-type intron splice site recognition and cleavage", "id": "GO:0000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000379", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" } ], "molecular_function": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" }, { "name": "tRNA-intron lyase activity", "id": "GO:0000213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000213", "evidence": [ { "database": "UniProtKB", "id": "Q8IP11", "url": "https://www.uniprot.org/uniprotkb/Q8IP11" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IPE5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPE5", "url": "https://www.uniprot.org/uniprotkb/Q8IPE5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 14042.0, "gene_names": "pal;CG31882;Dmel\\CG31882;Dmel_CG31882;NEST:bs35a07;bs35a07.y1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IPE5", "url": "https://www.uniprot.org/uniprotkb/Q8IPE5" } ], "pmid": "" } ], "biological_process": [ { "name": "sperm DNA condensation", "id": "GO:0035092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035092", "evidence": [ { "database": "UniProtKB", "id": "Q8IPE5", "url": "https://www.uniprot.org/uniprotkb/Q8IPE5" } ], "pmid": "" } ], "molecular_function": [ { "name": "H3-H4 histone complex chaperone activity", "id": "GO:0000510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000510", "evidence": [ { "database": "UniProtKB", "id": "Q8IPE5", "url": "https://www.uniprot.org/uniprotkb/Q8IPE5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IPF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPF1", "url": "https://www.uniprot.org/uniprotkb/Q8IPF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 123, "chemical_mass": 14949.0, "gene_names": "anon-AE003623.1;CG31609;Dmel\\CG31609;Dmel_CG31609;anon-AE003623.1", "protein_name": "BPTI/Kunitz inhibitor domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "Q8IPF1", "url": "https://www.uniprot.org/uniprotkb/Q8IPF1" } ], "pmid": "" }, { "name": "toxin activity", "id": "GO:0090729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090729", "evidence": [ { "database": "UniProtKB", "id": "Q8IPF1", "url": "https://www.uniprot.org/uniprotkb/Q8IPF1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IPF1", "url": "https://www.uniprot.org/uniprotkb/Q8IPF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IPR5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPR5", "url": "https://www.uniprot.org/uniprotkb/Q8IPR5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 35498.0, "gene_names": "Dmel\\CG15594;CG15594;Dmel\\CG15594;Dmel_CG15594", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VP68-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VP68", "url": "https://www.uniprot.org/uniprotkb/Q9VP68" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 446, "chemical_mass": 47074.0, "gene_names": "Dmel\\CG10512;CG10512;Dmel\\CG10512;Dmel_CG10512", "protein_name": "", "disease": [], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VP68", "url": "https://www.uniprot.org/uniprotkb/Q9VP68" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VP68-1", "start_pos": "395", "end_pos": "395", "site_lbl": "Thr395", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IPW2-2", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 548, "chemical_mass": 60406.0, "gene_names": "dock;2L19;CG3727;DOCK;Dm0447;Dmel\\CG3727;Dock;Nck;dck;dock;doc;l(2)04723", "protein_name": "SH2/SH3 adapter protein dreadlocks", "disease": [], "biological_process": [ { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "myoblast fusion", "id": "GO:0007520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007520", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" }, { "name": "male germline ring canal", "id": "GO:0035323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035323", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IPW2-2", "start_pos": "186", "end_pos": "186", "site_lbl": "Trp186", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "K", "comment": "Probably disrupts the binding pocket of SH3 domain 1. No effect on interaction with Pak. Unable to rescue R cell projection phenotype in loss of function mutants; when associated with Q-336.", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" }, { "database": "PubMed", "id": "10399914", "url": "https://glygen.org/publication/PubMed/10399914" }, { "database": "PubMed", "id": "9482841", "url": "https://glygen.org/publication/PubMed/9482841" } ] } ] }, { "uniprot_canonical_ac": "Q8IPW2-2", "start_pos": "289", "end_pos": "289", "site_lbl": "Trp289", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "K", "comment": "Probably disrupts the binding pocket of SH3 domain 2. Disrupts interaction with Pak. Unable to rescue R cell projection phenotype in loss of function mutants.", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" }, { "database": "PubMed", "id": "10399914", "url": "https://glygen.org/publication/PubMed/10399914" }, { "database": "PubMed", "id": "9482841", "url": "https://glygen.org/publication/PubMed/9482841" } ] } ] }, { "uniprot_canonical_ac": "Q8IPW2-2", "start_pos": "363", "end_pos": "363", "site_lbl": "Trp363", "weight": 0.0, "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "K", "comment": "Probably disrupts the binding pocket of SH3 domain 3. No effect on interaction with Pak. Unable to rescue R cell projection phenotype in loss of function mutants; when associated with Q-336.", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" }, { "database": "PubMed", "id": "9482841", "url": "https://glygen.org/publication/PubMed/9482841" }, { "database": "PubMed", "id": "10399914", "url": "https://glygen.org/publication/PubMed/10399914" } ] } ] }, { "uniprot_canonical_ac": "Q8IPW2-2", "start_pos": "474", "end_pos": "474", "site_lbl": "Arg474", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Probably disrupts SH2 phosphotyrosine binding pocket. Unable to rescue R cell projection phenotype in loss of function mutants; when associated with K-48 or K-225.", "evidence": [ { "database": "UniProtKB", "id": "Q8IPW2", "url": "https://www.uniprot.org/uniprotkb/Q8IPW2" }, { "database": "PubMed", "id": "9482841", "url": "https://glygen.org/publication/PubMed/9482841" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IPX4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 192, "chemical_mass": 21952.0, "gene_names": "CG16933;CG16933;CG31659;Dmel\\CG31659;Dmel_CG31659", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" }, { "name": "response to reactive oxygen species", "id": "GO:0000302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000302", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8IPX4", "url": "https://www.uniprot.org/uniprotkb/Q8IPX4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQ06-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ06", "url": "https://www.uniprot.org/uniprotkb/Q8IQ06" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 109, "chemical_mass": 12293.0, "gene_names": "BEST:RH19272;BEST:RH19272;CG31777;Dmel\\CG31777;Dmel_CG31777", "protein_name": "BPTI/Kunitz inhibitor domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ06", "url": "https://www.uniprot.org/uniprotkb/Q8IQ06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQ79-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 253, "chemical_mass": 29067.0, "gene_names": "sphinx1;CG32383;CG8555;Dmel\\CG32383;Dmel_CG32383;SPH194a;SPH194;Sphinx-1;Sphinx1;Spx1;sphinx-1;sphinx1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "defense response to Gram-negative bacterium", "id": "GO:0050829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050829", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" }, { "name": "Toll receptor ligand protein activation cascade", "id": "GO:0160032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160032", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ79", "url": "https://www.uniprot.org/uniprotkb/Q8IQ79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQ88-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ88", "url": "https://www.uniprot.org/uniprotkb/Q8IQ88" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 760, "chemical_mass": 83551.0, "gene_names": "Dmel\\CG14837;CG14837;Dmel\\CG14837;Dmel_CG14837", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQ89-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 291, "chemical_mass": 33062.0, "gene_names": "Dmel\\CG32376;CG32376;CG8528;Dmel\\CG32376;Dmel_CG32376;SP148b;SP148", "protein_name": "Peptidase S1 domain-containing protein", "disease": [ { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "pmid": "" }, { "name": "digestion", "id": "GO:0007586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007586", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "pmid": "" }, { "name": "hemolymph coagulation", "id": "GO:0042381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042381", "evidence": [ { "database": "UniProtKB", "id": "Q8IQ89", "url": "https://www.uniprot.org/uniprotkb/Q8IQ89" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQ89-1", "start_pos": "41", "end_pos": "41", "site_lbl": "Thr41", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 81, "chemical_mass": 9455.0, "gene_names": "ghi;CG32038;Dmel\\CG32038;Dmel_CG32038;fro;ghi", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" }, { "name": "actomyosin contractile ring contraction", "id": "GO:0000916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000916", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" }, { "name": "meiotic spindle organization", "id": "GO:0000212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000212", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" }, { "name": "meiosis I cytokinesis", "id": "GO:0007110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007110", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" }, { "name": "meiosis II cytokinesis", "id": "GO:0007111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007111", "evidence": [ { "database": "UniProtKB", "id": "Q8IQC4", "url": "https://www.uniprot.org/uniprotkb/Q8IQC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IQC4-1", "start_pos": "62", "end_pos": "62", "site_lbl": "Thr62", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQE7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQE7", "url": "https://www.uniprot.org/uniprotkb/Q8IQE7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 110, "chemical_mass": 12066.0, "gene_names": "Dmel\\CG32074;CG32074;Dmel\\CG32074;Dmel_CG32074", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQJ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 269, "chemical_mass": 30096.0, "gene_names": "Dmel\\CG10725;CG10725;Dmel\\CG10725;Dmel_CG10725", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ4" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ4" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q8IQJ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQJ4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQY1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQY1", "url": "https://www.uniprot.org/uniprotkb/Q8IQY1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 104, "chemical_mass": 11952.0, "gene_names": "Dmel\\CG32551;CG32551;Dmel\\CG32551;Dmel_CG32551", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IQZ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IQZ4", "url": "https://www.uniprot.org/uniprotkb/Q8IQZ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 239, "chemical_mass": 27082.0, "gene_names": "CG7871;CG32554;CG7871;Dmel\\CG32554;Dmel_CG32554", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IR50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IR50", "url": "https://www.uniprot.org/uniprotkb/Q8IR50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 262, "chemical_mass": 28863.0, "gene_names": "betaNACtes6;CG32598;Dmel\\CG32598;Dmel_CG32598;bNACtes6;betaNACtes6", "protein_name": "Transcription factor BTF3", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IR50", "url": "https://www.uniprot.org/uniprotkb/Q8IR50" } ], "pmid": "" }, { "name": "nascent polypeptide-associated complex", "id": "GO:0005854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005854", "evidence": [ { "database": "UniProtKB", "id": "Q8IR50", "url": "https://www.uniprot.org/uniprotkb/Q8IR50" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IR73-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IR73", "url": "https://www.uniprot.org/uniprotkb/Q8IR73" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 101, "chemical_mass": 11535.0, "gene_names": "Dmel\\CG32643;CG32643;Dmel\\CG32643;Dmel_CG32643;NEST:bs08h10", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IRA7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRA7", "url": "https://www.uniprot.org/uniprotkb/Q8IRA7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 565, "chemical_mass": 66380.0, "gene_names": "Dmel\\CG32246;CG32246;Dmel\\CG32246;Dmel_CG32246", "protein_name": "Nucleoporin Ndc1", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IRA7-1", "start_pos": "417", "end_pos": "417", "site_lbl": "Thr417", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 417, "start_aa": "Thr", "end_pos": 417, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr417", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IRB3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRB3", "url": "https://www.uniprot.org/uniprotkb/Q8IRB3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 415, "chemical_mass": 45017.0, "gene_names": "Dmel\\CG32241;CG32241;Dmel\\CG32241;Dmel_CG32241", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IRB3-1", "start_pos": "390", "end_pos": "390", "site_lbl": "Thr390", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 390, "start_aa": "Thr", "end_pos": 390, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr390", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q8IRB3-1", "start_pos": "68", "end_pos": "68", "site_lbl": "Thr68", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IRD1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 717, "chemical_mass": 80236.0, "gene_names": "Dmel\\CG12010;CG12010;Dmel\\CG12010;Dmel_CG12010", "protein_name": "AAA+ ATPase domain-containing protein", "disease": [ { "disease_id": "DOID:0050565", "name": "autosomal recessive nonsyndromic deafness", "description": "A nonsyndromic deafness characterized by an autosomal recessive inheritance mode.", "url": "https://disease-ontology.org/term/DOID:0050565", "evidence": [ { "id": "0050565", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050565" } ], "weight": 0.0 } ], "biological_process": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "mitotic spindle disassembly", "id": "GO:0051228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051228", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" } ], "cellular_component": [ { "name": "VCP-NPL4-UFD1 AAA ATPase complex", "id": "GO:0034098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034098", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q8IRD1", "url": "https://www.uniprot.org/uniprotkb/Q8IRD1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q8IRD1-1", "start_pos": "55", "end_pos": "55", "site_lbl": "Thr55", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IRF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1164, "chemical_mass": 133110.0, "gene_names": "CG8970;AC;CG32305;CG8970;Dmel\\CG32305;Dmel_CG32305", "protein_name": "adenylate cyclase", "disease": [ { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression.", "url": "https://disease-ontology.org/term/DOID:3312", "evidence": [ { "id": "3312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3312" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "adenylate cyclase activity", "id": "GO:0004016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004016", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" } ], "biological_process": [ { "name": "cAMP biosynthetic process", "id": "GO:0006171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006171", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q8IRF5", "url": "https://www.uniprot.org/uniprotkb/Q8IRF5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IRH3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRH3", "url": "https://www.uniprot.org/uniprotkb/Q8IRH3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 767, "chemical_mass": 90219.0, "gene_names": "Dmel\\CG32320;CG32320;Dmel\\CG32320;Dmel_CG32320", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8IRH3", "url": "https://www.uniprot.org/uniprotkb/Q8IRH3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IRK9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 197, "chemical_mass": 22845.0, "gene_names": "Rab9D;CG32678;Dmel\\CG32678;Dmel_CG32678;Rab9D;anon-AE003451.1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" } ], "cellular_component": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" } ], "biological_process": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "Q8IRK9", "url": "https://www.uniprot.org/uniprotkb/Q8IRK9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8IRL0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8IRL0", "url": "https://www.uniprot.org/uniprotkb/Q8IRL0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1506, "chemical_mass": 169458.0, "gene_names": "Dmel\\CG32681;CG32681;Dmel\\CG32681;Dmel_CG32681", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8MLP8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 247, "chemical_mass": 28183.0, "gene_names": "Not11;C2orf29;CG13567;Dmel\\CG13567;Dmel_CG13567;NOT11;Not11", "protein_name": "CCR4-NOT transcription complex subunit 11", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "CCR4-NOT complex", "id": "GO:0030014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030014", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0000289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000289", "evidence": [ { "database": "UniProtKB", "id": "Q8MLP8", "url": "https://www.uniprot.org/uniprotkb/Q8MLP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8MLS3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLS3", "url": "https://www.uniprot.org/uniprotkb/Q8MLS3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 122, "chemical_mass": 12825.0, "gene_names": "Dmel\\CG30413;CG30413;Dmel\\CG30413;Dmel_CG30413", "protein_name": "Salivary secreted peptide", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8MLU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MLU9", "url": "https://www.uniprot.org/uniprotkb/Q8MLU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2979, "chemical_mass": 321313.0, "gene_names": "Dmel\\CG13492;CG13492;Dmel\\CG13492;Dmel_CG13492", "protein_name": "DUF753 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q8MMD6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 497, "chemical_mass": 54835.0, "gene_names": "MFS1;CG11682;CG30272;Dmel\\CG30272;Dmel_CG30272;MFS1", "protein_name": "Putative inorganic phosphate cotransporter", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q8MMD6", "url": "https://www.uniprot.org/uniprotkb/Q8MMD6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9I7L3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7L3", "url": "https://www.uniprot.org/uniprotkb/Q9I7L3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 211, "chemical_mass": 23891.0, "gene_names": "Dmel\\CG17917;CG17917;Dmel\\CG17917;Dmel_CG17917", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9I7L3", "url": "https://www.uniprot.org/uniprotkb/Q9I7L3" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "Q9I7L3", "url": "https://www.uniprot.org/uniprotkb/Q9I7L3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9I7M8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 699, "chemical_mass": 79823.0, "gene_names": "Ku80;BG:DS09217.6;CG18801;DmKu80;Dmel\\CG18801;Dmel_CG18801;KU80;Ku80;Ku;ku80", "protein_name": "ATP-dependent DNA helicase II subunit 2", "disease": [ { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1749", "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ], "weight": 0.0 }, { "disease_id": "DOID:1993", "name": "rectum cancer", "description": "A colorectal cancer that is located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:1993", "evidence": [ { "id": "1993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1993" } ], "weight": 0.0 }, { "disease_id": "DOID:2513", "name": "basal cell carcinoma", "description": "A skin carcinoma affecting basal cells.", "url": "https://disease-ontology.org/term/DOID:2513", "evidence": [ { "id": "2513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2513" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow.", "url": "https://disease-ontology.org/term/DOID:9538", "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "response to ethanol", "id": "GO:0045471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045471", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" } ], "cellular_component": [ { "name": "Ku70:Ku80 complex", "id": "GO:0043564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043564", "evidence": [ { "database": "UniProtKB", "id": "Q9I7M8", "url": "https://www.uniprot.org/uniprotkb/Q9I7M8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V3R0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 254, "chemical_mass": 29030.0, "gene_names": "BG:BACR44L22.6;BG:BACR44L22.6;CG7631;Dmel\\CG7631;Dmel_CG7631", "protein_name": "Metalloendopeptidase", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9V3R0", "url": "https://www.uniprot.org/uniprotkb/Q9V3R0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V3Y0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 215, "chemical_mass": 24244.0, "gene_names": "Ankrd49;Ankrd49;BG:DS00929.2;C3;CG4140;DAnkrd49;Dmel\\CG4140;br10;l(2)35Be;l(2)br10", "protein_name": "Ankyrin repeat domain-containing protein 49", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of establishment of planar polarity", "id": "GO:0090175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090175", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9V3Y0-1", "start_pos": "156", "end_pos": "156", "site_lbl": "Ala156", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "T", "comment": "Lethal. Pupal wings containing clones display reduced levels of dsh, reduced asymmetric localization of stan, delayed trichome initiation, and formation of trichomes in the cell center rather than at the distal cell edge; when associated with A-87.", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" }, { "database": "PubMed", "id": "32750048", "url": "https://glygen.org/publication/PubMed/32750048" } ] } ] }, { "uniprot_canonical_ac": "Q9V3Y0-1", "start_pos": "87", "end_pos": "87", "site_lbl": "His87", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "Y", "comment": "Lethal. Pupal wings containing clones display reduced levels of dsh, reduced asymmetric localization of stan, delayed trichome initiation, and formation of trichomes in the cell center rather than at the distal cell edge; when associated with T-156.", "evidence": [ { "database": "UniProtKB", "id": "Q9V3Y0", "url": "https://www.uniprot.org/uniprotkb/Q9V3Y0" }, { "database": "PubMed", "id": "32750048", "url": "https://glygen.org/publication/PubMed/32750048" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V421-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 253, "chemical_mass": 29304.0, "gene_names": "BG:BACR44L22.3;BACR44L22.3;BG:BACR44L22.3;CG15253;Dmel\\CG15253;Dmel_CG15253", "protein_name": "Metalloendopeptidase", "disease": [], "molecular_function": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9V421", "url": "https://www.uniprot.org/uniprotkb/Q9V421" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V9P0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 390, "chemical_mass": 44184.0, "gene_names": "Dmel\\CG6675;CG6675;Dmel\\CG6675;Dmel_CG6675", "protein_name": "Lipase domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9V9P0", "url": "https://www.uniprot.org/uniprotkb/Q9V9P0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V9Q1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9Q1", "url": "https://www.uniprot.org/uniprotkb/Q9V9Q1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 631, "chemical_mass": 73056.0, "gene_names": "gi7302136;CG11630;Dmel\\CG11630;Dmel_CG11630;gi7302136", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Q1", "url": "https://www.uniprot.org/uniprotkb/Q9V9Q1" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Q1", "url": "https://www.uniprot.org/uniprotkb/Q9V9Q1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V9V4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9V4", "url": "https://www.uniprot.org/uniprotkb/Q9V9V4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 298, "chemical_mass": 34834.0, "gene_names": "Dmel\\CG11550;CG11550;Dmel\\CG11550;Dmel_CG11550", "protein_name": "CRAL-TRIO domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "Q9V9V4", "url": "https://www.uniprot.org/uniprotkb/Q9V9V4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V9W5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 50266.0, "gene_names": "Dmel\\CG1638;CG1638;Dmel\\CG1638;Dmel_CG1638;bs31f06.y1", "protein_name": "HotDog ACOT-type domain-containing protein", "disease": [], "molecular_function": [ { "name": "acetyl-CoA hydrolase activity", "id": "GO:0003986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003986", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" }, { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" } ], "biological_process": [ { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W5", "url": "https://www.uniprot.org/uniprotkb/Q9V9W5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V9W7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2089, "chemical_mass": 239692.0, "gene_names": "rod;CG1569;Dmel\\CG1569;Dmel_CG1569;EP3408;ROD;Rod1;Rod;pNB20A;rod", "protein_name": "", "disease": [], "cellular_component": [ { "name": "kinetochore microtubule", "id": "GO:0005828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005828", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "RZZ complex", "id": "GO:1990423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990423", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "acroblast", "id": "GO:0036063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036063", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of chromosome separation", "id": "GO:1905818", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905818", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "protein localization to kinetochore involved in kinetochore assembly", "id": "GO:1903394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903394", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051988", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "regulation of mitotic metaphase/anaphase transition", "id": "GO:0030071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030071", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "mitotic sister chromatid segregation", "id": "GO:0000070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" }, { "name": "protein localization to kinetochore", "id": "GO:0034501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" } ], "molecular_function": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9V9W7", "url": "https://www.uniprot.org/uniprotkb/Q9V9W7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9V9Y8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9V9Y8", "url": "https://www.uniprot.org/uniprotkb/Q9V9Y8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 298, "chemical_mass": 33487.0, "gene_names": "CAH6;CAH6;CG3669;Dmel\\CG3669;Dmel_CG3669", "protein_name": "Carbonic anhydrase", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0050997", "name": "cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome", "description": "A syndrome characterized by congenital onset of nonprogressive cerebellar ataxia, disturbed equilibrium, and mental retardation, associated with cerebellar hypoplasia.", "url": "https://disease-ontology.org/term/DOID:0050997", "evidence": [ { "id": "0050997", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050997" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:0111371", "name": "isolated hyperchlorhidrosis", "description": "A skin disease characterized by excessive loss of salt in sweat resulting in low levels of salt in the blood in the absence of other symptoms that has_material_basis_in homozygous or compound heterozygous mutation in the CA12 gene on chromosome 15q22.2.", "url": "https://disease-ontology.org/term/DOID:0111371", "evidence": [ { "id": "0111371", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111371" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:234", "name": "colon adenocarcinoma", "description": "A colon carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:234", "evidence": [ { "id": "234", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:234" } ], "weight": 0.0 }, { "disease_id": "DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.", "url": "https://disease-ontology.org/term/DOID:3748", "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ], "weight": 0.0 }, { "disease_id": "DOID:3883", "name": "Lynch syndrome", "description": "A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.", "url": "https://disease-ontology.org/term/DOID:3883", "evidence": [ { "id": "3883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3883" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:5015", "name": "fibrolamellar carcinoma", "description": "A hepatocellular carcinoma characterized microscopically by laminated fibrous layers interspersed between the tumour cells. The polygonal, deeply eosinophilic tumor cells arise in non-cirrhotic livers.", "url": "https://disease-ontology.org/term/DOID:5015", "evidence": [ { "id": "5015", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5015" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Y8", "url": "https://www.uniprot.org/uniprotkb/Q9V9Y8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Y8", "url": "https://www.uniprot.org/uniprotkb/Q9V9Y8" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "Q9V9Y8", "url": "https://www.uniprot.org/uniprotkb/Q9V9Y8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VA61-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 542, "chemical_mass": 62120.0, "gene_names": "PH4alphaNE2;CG9720;Dmel\\CG9720;Dmel_CG9720;PH4-alpha-NE2;PH4alphaNE2", "protein_name": "procollagen-proline 4-dioxygenase", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" } ], "biological_process": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q9VA61", "url": "https://www.uniprot.org/uniprotkb/Q9VA61" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VA77-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 666, "chemical_mass": 75264.0, "gene_names": "Dmel\\CG15534;CG15534;Dmel\\CG15534;Dmel_CG15534;aSMase;alphaSmase", "protein_name": "Sphingomyelin phosphodiesterase", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" } ], "biological_process": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "sphingomyelin catabolic process", "id": "GO:0006685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006685", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "hydrolase activity, acting on glycosyl bonds", "id": "GO:0016798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016798", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" }, { "name": "acid sphingomyelin phosphodiesterase activity", "id": "GO:0061750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061750", "evidence": [ { "database": "UniProtKB", "id": "Q9VA77", "url": "https://www.uniprot.org/uniprotkb/Q9VA77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VAN1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAN1", "url": "https://www.uniprot.org/uniprotkb/Q9VAN1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 168, "chemical_mass": 18884.0, "gene_names": "Dmel\\CG14515;CG14515;Dmel\\CG14515;Dmel_CG14515", "protein_name": "Reelin domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VAN1", "url": "https://www.uniprot.org/uniprotkb/Q9VAN1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VAQ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VAQ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 414, "chemical_mass": 46367.0, "gene_names": "Ssl2;CG11833;DmSSl2;Dmel\\CG11833;Dmel_CG11833;SSl2;Ssl2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VAQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VAQ9" } ], "pmid": "" }, { "name": "arylesterase activity", "id": "GO:0004064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004064", "evidence": [ { "database": "UniProtKB", "id": "Q9VAQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VAQ9" } ], "pmid": "" }, { "name": "lyase activity", "id": "GO:0016829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016829", "evidence": [ { "database": "UniProtKB", "id": "Q9VAQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VAQ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VAV6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 421, "chemical_mass": 48425.0, "gene_names": "Myst5;CG1894;Dmel\\CG1894;Dmel_CG1894;HAT;dmHAG407", "protein_name": "Histone acetyltransferase", "disease": [ { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:4467", "name": "clear cell renal cell carcinoma", "description": "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope.", "url": "https://disease-ontology.org/term/DOID:4467", "evidence": [ { "id": "4467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4467" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "MSL complex", "id": "GO:0072487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072487", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "NSL complex", "id": "GO:0044545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044545", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" }, { "name": "histone H4K16 acetyltransferase activity", "id": "GO:0046972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046972", "evidence": [ { "database": "UniProtKB", "id": "Q9VAV6", "url": "https://www.uniprot.org/uniprotkb/Q9VAV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VAW1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 970, "chemical_mass": 112796.0, "gene_names": "Moca-cyp;BEST:LD38313;CG1866;Dmel\\CG1866;Dmel_CG1866;Moca-cyp;anon-WO0147981.13;anon-WO0147981.4;anon-WO0147981.5;moca", "protein_name": "peptidylprolyl isomerase", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" } ], "molecular_function": [ { "name": "cyclosporin A binding", "id": "GO:0016018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016018", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "Q9VAW1", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VB06-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB06", "url": "https://www.uniprot.org/uniprotkb/Q9VB06" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 398, "chemical_mass": 45842.0, "gene_names": "HSPBAP1;CG12879;CG43320;Dmel\\CG43320;Dmel_CG43320;HSPBAP1", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VB06", "url": "https://www.uniprot.org/uniprotkb/Q9VB06" } ], "pmid": "" } ], "molecular_function": [ { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "Q9VB06", "url": "https://www.uniprot.org/uniprotkb/Q9VB06" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian behavior", "id": "GO:0048512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048512", "evidence": [ { "database": "UniProtKB", "id": "Q9VB06", "url": "https://www.uniprot.org/uniprotkb/Q9VB06" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VB32-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VB32", "url": "https://www.uniprot.org/uniprotkb/Q9VB32" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 898, "chemical_mass": 103537.0, "gene_names": "Dmel\\CG13978;CG13978;Dmel\\CG13978;Dmel_CG13978", "protein_name": "GPI ethanolamine phosphate transferase 1", "disease": [ { "disease_id": "DOID:0080138", "name": "multiple congenital anomalies-hypotonia-seizures syndrome 1", "description": "A multiple congenital anomalies-hypotonia-seizures syndrome that is characterized by neonatal hypotonia, lack of psychomotor development, seizures, dysmorphic features, and variable congenital anomalies involving the cardiac, urinary, and gastrointestinal systems and has_material_basis_in homozygous mutation in the PIGN gene on chromosome 18q21.", "url": "https://disease-ontology.org/term/DOID:0080138", "evidence": [ { "id": "0080138", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080138" } ], "weight": 0.0 }, { "disease_id": "DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies.", "url": "https://disease-ontology.org/term/DOID:4621", "evidence": [ { "id": "4621", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mannose-ethanolamine phosphotransferase activity", "id": "GO:0051377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051377", "evidence": [ { "database": "UniProtKB", "id": "Q9VB32", "url": "https://www.uniprot.org/uniprotkb/Q9VB32" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VB32", "url": "https://www.uniprot.org/uniprotkb/Q9VB32" } ], "pmid": "" } ], "biological_process": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "Q9VB32", "url": "https://www.uniprot.org/uniprotkb/Q9VB32" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VBE8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBE8", "url": "https://www.uniprot.org/uniprotkb/Q9VBE8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 121, "chemical_mass": 13462.0, "gene_names": "Dmel\\CG14237;CG14237;Dmel\\CG14237;Dmel_CG14237", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VBK7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 677, "chemical_mass": 77620.0, "gene_names": "Mco3;CG5959;Dmel\\CG5959;Dmel_CG5959;MCO3;MIP26036;Mco3;dMCO3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" } ], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" }, { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" } ], "biological_process": [ { "name": "copper ion homeostasis", "id": "GO:0055070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055070", "evidence": [ { "database": "UniProtKB", "id": "Q9VBK7", "url": "https://www.uniprot.org/uniprotkb/Q9VBK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VBK7-1", "start_pos": "318", "end_pos": "318", "site_lbl": "Thr318", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VBQ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 432, "chemical_mass": 49220.0, "gene_names": "Dmel\\CG4582;CG4582;Dmel\\CG4582;Dmel_CG4582", "protein_name": "Lipase domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VBQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VBS5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBS5", "url": "https://www.uniprot.org/uniprotkb/Q9VBS5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 415, "chemical_mass": 48044.0, "gene_names": "Dmel\\CG10559;CG10559;Dmel\\CG10559;Dmel_CG10559;Dro16-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q9VBS5", "url": "https://www.uniprot.org/uniprotkb/Q9VBS5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VBV9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBV9", "url": "https://www.uniprot.org/uniprotkb/Q9VBV9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 506, "chemical_mass": 55425.0, "gene_names": "Dmel\\CG31103;CG13655;CG31103;Dmel\\CG31103;Dmel_CG31103", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VBV9", "url": "https://www.uniprot.org/uniprotkb/Q9VBV9" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VBV9", "url": "https://www.uniprot.org/uniprotkb/Q9VBV9" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VBV9", "url": "https://www.uniprot.org/uniprotkb/Q9VBV9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VBW4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBW4", "url": "https://www.uniprot.org/uniprotkb/Q9VBW4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 235, "chemical_mass": 27051.0, "gene_names": "Dmel\\CG13653;CG13653;Dmel\\CG13653;Dmel_CG13653", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VBX3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 48705.0, "gene_names": "vig2;BcDNA:SD06613;CG11844;Dmel\\CG11844;Dmel_CG11844;Hero45;Vig2;anon-WO0118547.290;vig-2;vig2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" }, { "name": "polytene chromosome chromocenter", "id": "GO:0005701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005701", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" }, { "name": "polytene chromosome puff", "id": "GO:0005703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005703", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" } ], "biological_process": [ { "name": "heterochromatin organization", "id": "GO:0070828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070828", "evidence": [ { "database": "UniProtKB", "id": "Q9VBX3", "url": "https://www.uniprot.org/uniprotkb/Q9VBX3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VBZ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VBZ2", "url": "https://www.uniprot.org/uniprotkb/Q9VBZ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 222, "chemical_mass": 24565.0, "gene_names": "Dmel\\CG11786;CG11786;Dmel\\CG11786;Dmel_CG11786", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VBZ2-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VC32-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 841, "chemical_mass": 91815.0, "gene_names": "niki;CG10951;Dmel\\CG10951;Dmel_CG10951;NEK1;Niki;niki", "protein_name": "", "disease": [ { "disease_id": "DOID:0060259", "name": "renal-hepatic-pancreatic dysplasia", "description": "A physical disorder characterized by pancreatic fibrosis, renal dysplasia and hepatic dysgenesis; it is usual fatal soon after birth.", "url": "https://disease-ontology.org/term/DOID:0060259", "evidence": [ { "id": "0060259", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060259" } ], "weight": 0.0 }, { "disease_id": "DOID:0060558", "name": "lethal congenital contracture syndrome", "description": "A syndrome characterized by congenital nonprogressive joint contractures. The contractures can involve the upper or lower limbs and/or the vertebral column, leading to various degrees of flexion or extension limitations evident at birth.", "url": "https://disease-ontology.org/term/DOID:0060558", "evidence": [ { "id": "0060558", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060558" } ], "weight": 0.0 }, { "disease_id": "DOID:0081378", "name": "amyotrophic lateral sclerosis type 24", "description": "An amyotrophic lateral sclerosis that is characterized by adult-onset loss of motor neurons and that has_material_basis_in heterozygous mutation in the NEK1 gene on chromosome 4q33.", "url": "https://disease-ontology.org/term/DOID:0081378", "evidence": [ { "id": "0081378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081378" } ], "weight": 0.0 }, { "disease_id": "DOID:0110861", "name": "autosomal recessive polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion.", "url": "https://disease-ontology.org/term/DOID:0110861", "evidence": [ { "id": "0110861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110861" } ], "weight": 0.0 }, { "disease_id": "DOID:0111120", "name": "nephronophthisis 9", "description": "A nephronophthisis that has_material_basis_in homozygous mutation in the NEK8 gene on chromosome 17q11.", "url": "https://disease-ontology.org/term/DOID:0111120", "evidence": [ { "id": "0111120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111120" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q9VC32", "url": "https://www.uniprot.org/uniprotkb/Q9VC32" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VC68-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VC68", "url": "https://www.uniprot.org/uniprotkb/Q9VC68" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 280, "chemical_mass": 32025.0, "gene_names": "Dmel\\CG13622;CG13622;Dmel\\CG13622;Dmel_CG13622", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 306, "chemical_mass": 36088.0, "gene_names": "TBC1d7;BcDNA:LD17019;CG6182;Dmel\\CG6182;Dmel_CG6182;TBC1D7;TBC1d7;dTBC1D7", "protein_name": "TBC1 domain family member 7", "disease": [], "cellular_component": [ { "name": "TSC1-TSC2 complex", "id": "GO:0033596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033596", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" }, { "name": "TSC1-TSC2 complex binding", "id": "GO:0062078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062078", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" } ], "biological_process": [ { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "Q9VCC4", "url": "https://www.uniprot.org/uniprotkb/Q9VCC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 311, "chemical_mass": 35796.0, "gene_names": "Dmel\\CG10300;CG10300;Dmel\\CG10300;Dmel_CG10300", "protein_name": "CRAL-TRIO domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ2" } ], "pmid": "" }, { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ2" } ], "pmid": "" } ], "biological_process": [ { "name": "intermembrane lipid transfer", "id": "GO:0120009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120009", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCJ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 372, "chemical_mass": 42180.0, "gene_names": "Dmel\\CG16710;CG16710;Dmel\\CG16710;Dmel_CG16710;SP16;cSP16", "protein_name": "CLIP domain-containing serine protease", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VCJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VCJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCL3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCL3", "url": "https://www.uniprot.org/uniprotkb/Q9VCL3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 540, "chemical_mass": 62243.0, "gene_names": "Ugt303B2;CG10168;Dmel\\CG10168;Dmel_CG10168;UGT303B2;Ugt303B2", "protein_name": "", "disease": [], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VCL3", "url": "https://www.uniprot.org/uniprotkb/Q9VCL3" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VCL3", "url": "https://www.uniprot.org/uniprotkb/Q9VCL3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VCL3-1", "start_pos": "61", "end_pos": "61", "site_lbl": "Thr61", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCM8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 479, "chemical_mass": 54385.0, "gene_names": "Dmel\\CG4408;BEST:GH09055;CG4408;Dmel\\CG4408;Dmel_CG4408", "protein_name": "Zinc carboxypeptidase A 1", "disease": [ { "disease_id": "DOID:0060752", "name": "familial temporal lobe epilepsy 5", "description": "A temporal lobe epilepsy that has_material_basis_in heterozygous mutation in the CPA6 gene on chromosome 8q13.", "url": "https://disease-ontology.org/term/DOID:0060752", "evidence": [ { "id": "0060752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060752" } ], "weight": 0.0 }, { "disease_id": "DOID:0111308", "name": "familial febrile seizures 11", "description": "A familial febrile seizures that has_material_basis_in homozygous mutation in the CPA6 gene on chromosome 8p13.2.", "url": "https://disease-ontology.org/term/DOID:0111308", "evidence": [ { "id": "0111308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111308" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:2228", "name": "thrombocytosis", "description": "A blood platelet disease that is characterized by the presence of high platelet counts in the blood.", "url": "https://disease-ontology.org/term/DOID:2228", "evidence": [ { "id": "2228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2228" } ], "weight": 0.0 }, { "disease_id": "DOID:4989", "name": "pancreatitis", "description": "A pancreas disease that is characterized by inflammation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:4989", "evidence": [ { "id": "4989", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4989" } ], "weight": 0.0 }, { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "Q9VCM8", "url": "https://www.uniprot.org/uniprotkb/Q9VCM8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VCM8-1", "start_pos": "457", "end_pos": "457", "site_lbl": "Thr457", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 457, "start_aa": "Thr", "end_pos": 457, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr457", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCN6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 718, "chemical_mass": 81738.0, "gene_names": "Cdc16;APC6;Apc6;CDC16;CG6759;Cdc16;Dmcdc16;Dmel\\CG6759;Dmel_CG6759;cdc16", "protein_name": "", "disease": [], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "positive regulation of mitotic metaphase/anaphase transition", "id": "GO:0045842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045842", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "regulation of mitotic metaphase/anaphase transition", "id": "GO:0030071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030071", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "compound eye photoreceptor cell differentiation", "id": "GO:0001751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001751", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" }, { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" } ], "molecular_function": [ { "name": "enzyme-substrate adaptor activity", "id": "GO:0140767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140767", "evidence": [ { "database": "UniProtKB", "id": "Q9VCN6", "url": "https://www.uniprot.org/uniprotkb/Q9VCN6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCQ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 211, "chemical_mass": 23509.0, "gene_names": "Dmel\\CG13829;CG13829;Dmel\\CG13829;Dmel_CG13829", "protein_name": "", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ2" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ2" } ], "pmid": "" } ], "biological_process": [ { "name": "vacuolar proton-transporting V-type ATPase complex assembly", "id": "GO:0070072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070072", "evidence": [ { "database": "UniProtKB", "id": "Q9VCQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VCQ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCT6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCT6", "url": "https://www.uniprot.org/uniprotkb/Q9VCT6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 466, "chemical_mass": 53239.0, "gene_names": "Dmel\\CG13840;CG13840;Dmel\\CG13840;Dmel_CG13840", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCV8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCV8", "url": "https://www.uniprot.org/uniprotkb/Q9VCV8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 772, "chemical_mass": 89202.0, "gene_names": "Dmel\\CG13842;CG13842;Dmel\\CG13842;Dmel_CG13842", "protein_name": "Coiled-coil protein 142 C-terminal domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VCW2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 830, "chemical_mass": 92829.0, "gene_names": "cd;CG6969;Dmel\\CG6969;Dmel_CG6969;HPX6;PHS;cd", "protein_name": "", "disease": [ { "disease_id": "DOID:0050328", "name": "congenital hypothyroidism", "description": "A hypothyroidism that is present at birth.", "url": "https://disease-ontology.org/term/DOID:0050328", "evidence": [ { "id": "0050328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050328" } ], "weight": 0.0 }, { "disease_id": "DOID:0080162", "name": "lupus nephritis", "description": "A glomerulonephritis that is characterized by inflammation of the kidneys resulting from systemic lupus erythematosus.", "url": "https://disease-ontology.org/term/DOID:0080162", "evidence": [ { "id": "0080162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080162" } ], "weight": 0.0 }, { "disease_id": "DOID:0080348", "name": "Alzheimer's disease 1", "description": "An Alzheimer's disease that has_material_basis_in mutation heterozygous mutation in the APP gene, which encodes the amyloid precursor protein, on chromosome 21q21.", "url": "https://disease-ontology.org/term/DOID:0080348", "evidence": [ { "id": "0080348", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080348" } ], "weight": 0.0 }, { "disease_id": "DOID:0112186", "name": "thyroid dyshormonogenesis 2A", "description": "A familial thyroid dyshormonogenesis that has_material_basis_in homozygous or compound heterozygous mutation in TPO on chromosome 2p25.3.", "url": "https://disease-ontology.org/term/DOID:0112186", "evidence": [ { "id": "0112186", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112186" } ], "weight": 0.0 }, { "disease_id": "DOID:1287", "name": "cardiovascular system disease", "description": "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.", "url": "https://disease-ontology.org/term/DOID:1287", "evidence": [ { "id": "1287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1287" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1591", "name": "renovascular hypertension", "description": "", "url": "https://disease-ontology.org/term/DOID:1591", "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ], "weight": 0.0 }, { "disease_id": "DOID:161", "name": "keratosis", "description": "A skin disease characterized_by growth of keratin on the skin or mucous membranes.", "url": "https://disease-ontology.org/term/DOID:161", "evidence": [ { "id": "161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:161" } ], "weight": 0.0 }, { "disease_id": "DOID:1679", "name": "cystitis", "description": "A bladder disease that is characterized by inflammation of the bladder.", "url": "https://disease-ontology.org/term/DOID:1679", "evidence": [ { "id": "1679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1679" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney.", "url": "https://disease-ontology.org/term/DOID:2921", "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both.", "url": "https://disease-ontology.org/term/DOID:3083", "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 }, { "disease_id": "DOID:865", "name": "vasculitis", "description": "A vascular disease that is characterized by inflammation of the blood vessels.", "url": "https://disease-ontology.org/term/DOID:865", "evidence": [ { "id": "865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:865" } ], "weight": 0.0 }, { "disease_id": "DOID:874", "name": "bacterial pneumonia", "description": "A pneumonia involving inflammation of the lungs caused by bacteria.", "url": "https://disease-ontology.org/term/DOID:874", "evidence": [ { "id": "874", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:874" } ], "weight": 0.0 }, { "disease_id": "DOID:9362", "name": "status asthmaticus", "description": "An acute asthma that is characterized by an acute episode with a progressive severity that is poorly responsive to standard therapeutic measures, regardless of disease severity or phenotypic variant.", "url": "https://disease-ontology.org/term/DOID:9362", "evidence": [ { "id": "9362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9362" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "pigment granule", "id": "GO:0048770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048770", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" } ], "biological_process": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "kynurenine metabolic process", "id": "GO:0070189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070189", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "cellular process involved in reproduction in multicellular organism", "id": "GO:0022412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022412", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "ommochrome biosynthetic process", "id": "GO:0006727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006727", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" }, { "name": "peroxidase activity", "id": "GO:0004601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004601", "evidence": [ { "database": "UniProtKB", "id": "Q9VCW2", "url": "https://www.uniprot.org/uniprotkb/Q9VCW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VD47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD47", "url": "https://www.uniprot.org/uniprotkb/Q9VD47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 444, "chemical_mass": 49232.0, "gene_names": "Dmel\\CG13407;CG13407;Dmel\\CG13407;Dmel_CG13407", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VD62-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 562, "chemical_mass": 64813.0, "gene_names": "Qsox3;CG6690;Dmel\\CG6690;Dmel_CG6690;Qsox3", "protein_name": "Sulfhydryl oxidase", "disease": [ { "disease_id": "DOID:14679", "name": "VACTERL association", "description": "A syndrome that is characterized by the presence of at least three of the following: vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities.", "url": "https://disease-ontology.org/term/DOID:14679", "evidence": [ { "id": "14679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14679" } ], "weight": 0.0 } ], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "mating", "id": "GO:0007618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007618", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" } ], "molecular_function": [ { "name": "flavin-dependent sulfhydryl oxidase activity", "id": "GO:0016971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016971", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "Q9VD62", "url": "https://www.uniprot.org/uniprotkb/Q9VD62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VD91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VD91", "url": "https://www.uniprot.org/uniprotkb/Q9VD91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 260, "chemical_mass": 29788.0, "gene_names": "Jhbp16;CG15497;Dmel\\CG15497;Dmel_CG15497;JHBP16;Jhbp16", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VD91", "url": "https://www.uniprot.org/uniprotkb/Q9VD91" } ], "pmid": "" } ], "biological_process": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "Q9VD91", "url": "https://www.uniprot.org/uniprotkb/Q9VD91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDA3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 200, "chemical_mass": 22517.0, "gene_names": "CheB93a;CG15503;CheB93a;Dmel\\CG15503;Dmel_CG15503", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" }, { "name": "detection of pheromone", "id": "GO:0043695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043695", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA3", "url": "https://www.uniprot.org/uniprotkb/Q9VDA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDA5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDA5", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 526, "chemical_mass": 59654.0, "gene_names": "Ugt49B2;CG6475;Dmel\\CG6475;Dmel_CG6475;UGT49B2;Ugt49B2", "protein_name": "UDP-glucuronosyltransferase", "disease": [ { "disease_id": "DOID:10211", "name": "cholelithiasis", "description": "", "url": "https://disease-ontology.org/term/DOID:10211", "evidence": [ { "id": "10211", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10211" } ], "weight": 0.0 }, { "disease_id": "DOID:11151", "name": "cholecystolithiasis", "description": "", "url": "https://disease-ontology.org/term/DOID:11151", "evidence": [ { "id": "11151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11151" } ], "weight": 0.0 }, { "disease_id": "DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus.", "url": "https://disease-ontology.org/term/DOID:1380", "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2739", "name": "Gilbert syndrome", "description": "A bilirubin metabolic disorder that involves elevated levels of unconjugated bilirubin as bilirubin is not being conjugated as a result of reduced glucuronyltransferase activity.", "url": "https://disease-ontology.org/term/DOID:2739", "evidence": [ { "id": "2739", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2739" } ], "weight": 0.0 }, { "disease_id": "DOID:2741", "name": "bilirubin metabolic disorder", "description": "An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism.", "url": "https://disease-ontology.org/term/DOID:2741", "evidence": [ { "id": "2741", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2741" } ], "weight": 0.0 }, { "disease_id": "DOID:3803", "name": "Crigler-Najjar syndrome", "description": "A bilirubin metabolic disorder that involves a build up of bilirubin as bilirubin is not being broken down as a result of a lack or deficiency of the enzyme uridine diphosphate glycosyltransferase (UGT).", "url": "https://disease-ontology.org/term/DOID:3803", "evidence": [ { "id": "3803", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3803" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells.", "url": "https://disease-ontology.org/term/DOID:4947", "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ], "weight": 0.0 }, { "disease_id": "DOID:4988", "name": "alcoholic pancreatitis", "description": "", "url": "https://disease-ontology.org/term/DOID:4988", "evidence": [ { "id": "4988", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4988" } ], "weight": 0.0 }, { "disease_id": "DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:7998", "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ], "weight": 0.0 }, { "disease_id": "DOID:8692", "name": "myeloid leukemia", "description": "A leukemia that is located_in myeloid tissue.", "url": "https://disease-ontology.org/term/DOID:8692", "evidence": [ { "id": "8692", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8692" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA5", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA5", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VDA5", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDD4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDD4", "url": "https://www.uniprot.org/uniprotkb/Q9VDD4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 428, "chemical_mass": 48855.0, "gene_names": "Dmel\\CG5810;CG5810;CT18214;Dmel\\CG5810;Dmel_CG5810", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 325, "chemical_mass": 35636.0, "gene_names": "dmrt93B;CG5737;Dmel\\CG5737;Dmel_CG5737;dmrt93B;dmrt93b", "protein_name": "", "disease": [ { "disease_id": "DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40.", "url": "https://disease-ontology.org/term/DOID:5426", "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q9VDF1", "url": "https://www.uniprot.org/uniprotkb/Q9VDF1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDF1-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Thr32", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 32, "start_aa": "Thr", "end_pos": 32, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr32", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDN3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 678, "chemical_mass": 76752.0, "gene_names": "Ir92a;92a;CG15685;DmelIR92a;Dmel\\CG15685;Dmel_CG15685;IR92a;Ir92a", "protein_name": "", "disease": [], "biological_process": [ { "name": "cellular response to ammonium ion", "id": "GO:0071242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071242", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "positive regulation of calcium-mediated signaling", "id": "GO:0050850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050850", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "cellular response to amine stimulus", "id": "GO:0071418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071418", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" } ], "molecular_function": [ { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" }, { "name": "extracellular ammonia-gated monoatomic ion channel activity", "id": "GO:0036081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036081", "evidence": [ { "database": "UniProtKB", "id": "Q9VDN3", "url": "https://www.uniprot.org/uniprotkb/Q9VDN3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDN3-1", "start_pos": "161", "end_pos": "161", "site_lbl": "Thr161", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDP6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDP6", "url": "https://www.uniprot.org/uniprotkb/Q9VDP6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 461, "chemical_mass": 49823.0, "gene_names": "Dmel\\CG17199;CG17199;Dmel\\CG17199;Dmel_CG17199", "protein_name": "", "disease": [], "molecular_function": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VDP6", "url": "https://www.uniprot.org/uniprotkb/Q9VDP6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VDP6-1", "start_pos": "159", "end_pos": "159", "site_lbl": "Thr159", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 159, "start_aa": "Thr", "end_pos": 159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr159", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDU4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 537, "chemical_mass": 60202.0, "gene_names": "Acsx1L;Acsx1L;CG6300;Dmel\\CG6300;Dmel_CG6300", "protein_name": "", "disease": [], "biological_process": [ { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "pmid": "" }, { "name": "fatty-acyl-CoA biosynthetic process", "id": "GO:0046949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046949", "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "pmid": "" } ], "cellular_component": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "pmid": "" } ], "molecular_function": [ { "name": "long-chain fatty acid-CoA ligase activity", "id": "GO:0004467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004467", "evidence": [ { "database": "UniProtKB", "id": "Q9VDU4", "url": "https://www.uniprot.org/uniprotkb/Q9VDU4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDY6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 368, "chemical_mass": 41742.0, "gene_names": "Polr2M;CG3773;Dmel\\CG3773;Dmel_CG3773;Gdn1;Gdown1;Polr2M;anon-EST:fe2D10;anon-EST:fe2D12", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" }, { "name": "RNA polymerase II, core complex", "id": "GO:0005665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005665", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" } ], "biological_process": [ { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" } ], "molecular_function": [ { "name": "transcription elongation factor activity", "id": "GO:0003711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003711", "evidence": [ { "database": "UniProtKB", "id": "Q9VDY6", "url": "https://www.uniprot.org/uniprotkb/Q9VDY6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VDZ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 459, "chemical_mass": 52875.0, "gene_names": "CG117799;BEST:GM03811;BcDNA:GM03811;CG117799;CG11779;Dmel\\CG11779;Dmel_CG11779;GH-18370", "protein_name": "Mitochondrial import inner membrane translocase subunit TIM44", "disease": [ { "disease_id": "DOID:13207", "name": "proliferative diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:13207", "evidence": [ { "id": "13207", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13207" } ], "weight": 0.0 }, { "disease_id": "DOID:8161", "name": "oncocytic carcinoma of the thyroid", "description": "A thyroid gland follicular carcinoma that is characterized by the presence of large cells with eosinophilic granular cytoplasm and pleomorphic nuclei with prominent, eosinophilic nucleoli.", "url": "https://disease-ontology.org/term/DOID:8161", "evidence": [ { "id": "8161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8161" } ], "weight": 0.0 }, { "disease_id": "DOID:8947", "name": "diabetic retinopathy", "description": "", "url": "https://disease-ontology.org/term/DOID:8947", "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" }, { "name": "PAM complex, Tim23 associated import motor", "id": "GO:0001405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001405", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" } ], "biological_process": [ { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "Q9VDZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VDZ7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VEH2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEH2", "url": "https://www.uniprot.org/uniprotkb/Q9VEH2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 260, "chemical_mass": 29157.0, "gene_names": "Dmel\\CG7523;CG7523;Dmel\\CG7523;Dmel_CG7523", "protein_name": "Transmembrane protein 192", "disease": [], "cellular_component": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH2", "url": "https://www.uniprot.org/uniprotkb/Q9VEH2" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH2", "url": "https://www.uniprot.org/uniprotkb/Q9VEH2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VEH5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEH5", "url": "https://www.uniprot.org/uniprotkb/Q9VEH5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 181, "chemical_mass": 18171.0, "gene_names": "AttD;ATTD;AttD;Attacin D;Att;CG7629;Dmel\\CG7629;Dmel_CG7629;att D;attD;attacin-D;att", "protein_name": "", "disease": [], "biological_process": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH5", "url": "https://www.uniprot.org/uniprotkb/Q9VEH5" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH5", "url": "https://www.uniprot.org/uniprotkb/Q9VEH5" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "Q9VEH5", "url": "https://www.uniprot.org/uniprotkb/Q9VEH5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VEH5-1", "start_pos": "37", "end_pos": "37", "site_lbl": "Thr37", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VEK5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 465, "chemical_mass": 50947.0, "gene_names": "Dmel\\CG17283;CG17283;Dmel\\CG17283;Dmel_CG17283", "protein_name": "Peptidase A1 domain-containing protein", "disease": [], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "pmid": "" } ], "cellular_component": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "pmid": "" } ], "molecular_function": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "Q9VEK5", "url": "https://www.uniprot.org/uniprotkb/Q9VEK5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VEL5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEL5", "url": "https://www.uniprot.org/uniprotkb/Q9VEL5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 225, "chemical_mass": 25026.0, "gene_names": "CG5329;CG31418;CG5329;Dmel\\CG31418;Dmel_CG31418", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VEL5", "url": "https://www.uniprot.org/uniprotkb/Q9VEL5" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VEL5", "url": "https://www.uniprot.org/uniprotkb/Q9VEL5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VEL5-1", "start_pos": "25", "end_pos": "25", "site_lbl": "Thr25", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VEL5-1", "start_pos": "29", "end_pos": "29", "site_lbl": "Thr29", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VEM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 643, "chemical_mass": 73515.0, "gene_names": "Dmel\\CG5265;CG5265;CRAT;CrAT;Dmel\\CG5265;Dmel_CG5265", "protein_name": "Choline/carnitine acyltransferase domain-containing protein", "disease": [ { "disease_id": "DOID:0110734", "name": "neurodegeneration with brain iron accumulation", "description": "A neurodegenerative disease characterized by progressive iron accumulation in the basal ganglia and other regions of the brain, resulting in extrapyramidal movements, such as parkinsonism and dystonia.", "url": "https://disease-ontology.org/term/DOID:0110734", "evidence": [ { "id": "0110734", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110734" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation using acyl-CoA oxidase", "id": "GO:0033540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033540", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" }, { "name": "carnitine metabolic process, CoA-linked", "id": "GO:0019254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019254", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" } ], "molecular_function": [ { "name": "carnitine O-acetyltransferase activity", "id": "GO:0004092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004092", "evidence": [ { "database": "UniProtKB", "id": "Q9VEM4", "url": "https://www.uniprot.org/uniprotkb/Q9VEM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VEN2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 979, "chemical_mass": 109539.0, "gene_names": "cal1;CAL1;CG5148;CLD2;Cal1;Dmel\\CG5148;Dmel_CG5148;cal1", "protein_name": "", "disease": [], "biological_process": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "female meiosis chromosome segregation", "id": "GO:0016321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016321", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "CENP-A containing chromatin assembly", "id": "GO:0034080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034080", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "Q9VEN2", "url": "https://www.uniprot.org/uniprotkb/Q9VEN2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VEN2-1", "start_pos": "512", "end_pos": "512", "site_lbl": "Thr512", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 512, "start_aa": "Thr", "end_pos": 512, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr512", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VET3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VET3", "url": "https://www.uniprot.org/uniprotkb/Q9VET3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 119, "chemical_mass": 13471.0, "gene_names": "Dmel\\CG14903;CG14903;Dmel\\CG14903;Dmel_CG14903", "protein_name": "peptidyl-tRNA hydrolase", "disease": [], "molecular_function": [ { "name": "peptidyl-tRNA hydrolase activity", "id": "GO:0004045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004045", "evidence": [ { "database": "UniProtKB", "id": "Q9VET3", "url": "https://www.uniprot.org/uniprotkb/Q9VET3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VEV6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 286, "chemical_mass": 32540.0, "gene_names": "Dmel\\CG14881;CG14881;Dmel\\CG14881;Dmel_CG14881", "protein_name": "MaoC-like domain-containing protein", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-hydroxyacyl-CoA dehydratase activity", "id": "GO:0018812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018812", "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "pmid": "" }, { "name": "(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity", "id": "GO:0019171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019171", "evidence": [ { "database": "UniProtKB", "id": "Q9VEV6", "url": "https://www.uniprot.org/uniprotkb/Q9VEV6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 562, "chemical_mass": 60433.0, "gene_names": "Amt;Amt;CG6499;Dmel\\CG6499;Dmel_CG6499", "protein_name": "Ammonium transporter", "disease": [ { "disease_id": "DOID:14219", "name": "renal tubular acidosis", "description": "A renal tubular transport disease characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic acidosis.", "url": "https://disease-ontology.org/term/DOID:14219", "evidence": [ { "id": "14219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14219" } ], "weight": 0.0 } ], "biological_process": [ { "name": "cellular response to ammonium ion", "id": "GO:0071242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071242", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" }, { "name": "ammonium homeostasis", "id": "GO:0097272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097272", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" }, { "name": "ammonium transmembrane transport", "id": "GO:0072488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072488", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" }, { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ammonium channel activity", "id": "GO:0008519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008519", "evidence": [ { "database": "UniProtKB", "id": "Q9VFA9", "url": "https://www.uniprot.org/uniprotkb/Q9VFA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFE1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFE1", "url": "https://www.uniprot.org/uniprotkb/Q9VFE1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 364, "chemical_mass": 41222.0, "gene_names": "Dmel\\CG14861;CG14861;Dmel\\CG14861;Dmel_CG14861", "protein_name": "EF-hand domain-containing protein", "disease": [], "molecular_function": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9VFE1", "url": "https://www.uniprot.org/uniprotkb/Q9VFE1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFN1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFN1", "url": "https://www.uniprot.org/uniprotkb/Q9VFN1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 319, "chemical_mass": 35669.0, "gene_names": "Dmel\\CG14357;CG14357;Dmel\\CG14357;Dmel_CG14357", "protein_name": "C2H2-type domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFS4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFS4", "url": "https://www.uniprot.org/uniprotkb/Q9VFS4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 310, "chemical_mass": 35393.0, "gene_names": "Dmel\\CG14367;CG14367;Dmel\\CG14367;Dmel_CG14367", "protein_name": "Cilia- and flagella-associated protein 36", "disease": [], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VFS4", "url": "https://www.uniprot.org/uniprotkb/Q9VFS4" } ], "pmid": "" } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q9VFS4", "url": "https://www.uniprot.org/uniprotkb/Q9VFS4" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "Q9VFS4", "url": "https://www.uniprot.org/uniprotkb/Q9VFS4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFU2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFU2", "url": "https://www.uniprot.org/uniprotkb/Q9VFU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 112, "chemical_mass": 12160.0, "gene_names": "Dmel\\CG14369;CG14369;Dmel\\CG14369;Dmel_CG14369", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFU4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFU4", "url": "https://www.uniprot.org/uniprotkb/Q9VFU4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 194, "chemical_mass": 21192.0, "gene_names": "Dmel\\CG12538;CG12538;Dmel\\CG12538;Dmel_CG12538", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFW3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFW3", "url": "https://www.uniprot.org/uniprotkb/Q9VFW3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 183, "chemical_mass": 21453.0, "gene_names": "CheA87a;CG14379;CheA87a;Dmel\\CG14379;Dmel_CG14379", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VFW3", "url": "https://www.uniprot.org/uniprotkb/Q9VFW3" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory perception of chemical stimulus", "id": "GO:0007606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007606", "evidence": [ { "database": "UniProtKB", "id": "Q9VFW3", "url": "https://www.uniprot.org/uniprotkb/Q9VFW3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VFY4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VFY4", "url": "https://www.uniprot.org/uniprotkb/Q9VFY4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 168, "chemical_mass": 19105.0, "gene_names": "Dmel\\CG14380;CG14380;Dmel\\CG14380;Dmel_CG14380", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VG30-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG30", "url": "https://www.uniprot.org/uniprotkb/Q9VG30" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 530, "chemical_mass": 59128.0, "gene_names": "Ugt37A2;CG5724;Dmel\\CG5724;Dmel_CG5724;UGT37A2;Ugt37A2", "protein_name": "", "disease": [ { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VG30", "url": "https://www.uniprot.org/uniprotkb/Q9VG30" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VG30", "url": "https://www.uniprot.org/uniprotkb/Q9VG30" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VG47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 430, "chemical_mass": 49177.0, "gene_names": "Dmel\\CG11608;CG11608;Dmel\\CG11608;Dmel_CG11608", "protein_name": "Lipase", "disease": [ { "disease_id": "DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31.", "url": "https://disease-ontology.org/term/DOID:0080217", "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ], "weight": 0.0 }, { "disease_id": "DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.", "url": "https://disease-ontology.org/term/DOID:14497", "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ], "weight": 0.0 } ], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" } ], "molecular_function": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VG47", "url": "https://www.uniprot.org/uniprotkb/Q9VG47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VG62-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG62", "url": "https://www.uniprot.org/uniprotkb/Q9VG62" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 485, "chemical_mass": 53165.0, "gene_names": "trus;CG5333;Dmel\\CG5333;Dmel_CG5333;trus", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VG62", "url": "https://www.uniprot.org/uniprotkb/Q9VG62" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9VG62", "url": "https://www.uniprot.org/uniprotkb/Q9VG62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VG62-1", "start_pos": "35", "end_pos": "35", "site_lbl": "Thr35", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VG72-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 501, "chemical_mass": 58790.0, "gene_names": "Dmel\\CG5245;CG5245;Dmel\\CG5245;Dmel_CG5245;anon-WO0118547.611", "protein_name": "Zinc finger protein 865", "disease": [], "biological_process": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VG72", "url": "https://www.uniprot.org/uniprotkb/Q9VG72" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VGB6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 292, "chemical_mass": 32963.0, "gene_names": "Pgam2;CG17645;Dmel\\CG17645;Dmel_CG17645;Pglym87;Pglym;pglym87", "protein_name": "Phosphoglycerate mutase", "disease": [ { "disease_id": "DOID:0080108", "name": "myoglobinuria", "description": "A myopathy that is characterized by an increased urinary excretion of myoglobin.", "url": "https://disease-ontology.org/term/DOID:0080108", "evidence": [ { "id": "0080108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080108" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "bisphosphoglycerate mutase activity", "id": "GO:0004082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004082", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" }, { "name": "phosphoglycerate mutase activity", "id": "GO:0004619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004619", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" } ], "biological_process": [ { "name": "gluconeogenesis", "id": "GO:0006094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006094", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" }, { "name": "canonical glycolysis", "id": "GO:0061621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061621", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB6", "url": "https://www.uniprot.org/uniprotkb/Q9VGB6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VGB8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGB8", "url": "https://www.uniprot.org/uniprotkb/Q9VGB8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 267, "chemical_mass": 29147.0, "gene_names": "Dmel\\CG3916;CG3916;Dmel\\CG3916;Dmel_CG3916;SP154", "protein_name": "trypsin", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB8", "url": "https://www.uniprot.org/uniprotkb/Q9VGB8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB8", "url": "https://www.uniprot.org/uniprotkb/Q9VGB8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VGB8", "url": "https://www.uniprot.org/uniprotkb/Q9VGB8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VGQ3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 264, "chemical_mass": 29513.0, "gene_names": "scpr-A;CG5207;Dmel\\CG5207;Dmel_CG5207;SCPR-A;bs03f04.y1;cg5207;scp-A;scpr-A", "protein_name": "Venom allergen-1", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ3" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VGQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VGT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGT4", "url": "https://www.uniprot.org/uniprotkb/Q9VGT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 521, "chemical_mass": 59682.0, "gene_names": "Ugt302E1;AC 006491C;CG4739;Dmel\\CG4739;Dmel_CG4739;UGT302E1;Ugt302E1;Ugt86Dc", "protein_name": "UDP-glucuronosyltransferase", "disease": [], "molecular_function": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VGT4", "url": "https://www.uniprot.org/uniprotkb/Q9VGT4" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q9VGT4", "url": "https://www.uniprot.org/uniprotkb/Q9VGT4" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VGT4", "url": "https://www.uniprot.org/uniprotkb/Q9VGT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VGW4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VGW4", "url": "https://www.uniprot.org/uniprotkb/Q9VGW4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2851, "chemical_mass": 319200.0, "gene_names": "Dmel\\CG14692;CG14692;Dmel\\CG14692;Dmel_CG14692", "protein_name": "RIIa domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VGW4-1", "start_pos": "2238", "end_pos": "2238", "site_lbl": "Thr2238", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2238, "start_aa": "Thr", "end_pos": 2238, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2238", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VGW4-1", "start_pos": "609", "end_pos": "609", "site_lbl": "Thr609", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 609, "start_aa": "Thr", "end_pos": 609, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr609", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VH13-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH13", "url": "https://www.uniprot.org/uniprotkb/Q9VH13" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 240, "chemical_mass": 25422.0, "gene_names": "Dmel\\CG12420;CG12420;Dmel\\CG12420;Dmel_CG12420", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VH59-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 265, "chemical_mass": 30988.0, "gene_names": "Dmel\\CG8534;CG8534;Dmel\\CG8534;Dmel_CG8534", "protein_name": "Elongation of very long chain fatty acids protein", "disease": [], "cellular_component": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" } ], "biological_process": [ { "name": "sphingolipid biosynthetic process", "id": "GO:0030148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030148", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "fatty acid elongation", "id": "GO:0030497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030497", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "fatty acid elongation, monounsaturated fatty acid", "id": "GO:0034625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034625", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "fatty acid elongation, polyunsaturated fatty acid", "id": "GO:0034626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034626", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "fatty acid elongation, saturated fatty acid", "id": "GO:0019367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019367", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" }, { "name": "very long-chain fatty acid biosynthetic process", "id": "GO:0042761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042761", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" } ], "molecular_function": [ { "name": "fatty acid elongase activity", "id": "GO:0009922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009922", "evidence": [ { "database": "UniProtKB", "id": "Q9VH59", "url": "https://www.uniprot.org/uniprotkb/Q9VH59" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VHF6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 520, "chemical_mass": 59764.0, "gene_names": "Aduk;ADUK;Aduk;CG8866;Dmel\\CG8866;Dmel_CG8866;UNC 51-like;dULK3", "protein_name": "Serine/threonine-protein kinase ULK3", "disease": [], "biological_process": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "Q9VHF6", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VHG7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 277, "chemical_mass": 31807.0, "gene_names": "Dmel\\CG16736;CG16736;Dmel\\CG16736;Dmel_CG16736", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" } ], "biological_process": [ { "name": "sulfate transmembrane transport", "id": "GO:1902358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902358", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "thiosulfate transport", "id": "GO:0015709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015709", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "oxaloacetate transport", "id": "GO:0015729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015729", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "phosphate ion transmembrane transport", "id": "GO:0035435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035435", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "succinate transmembrane transport", "id": "GO:0071422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071422", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "malate transmembrane transport", "id": "GO:0071423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071423", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" } ], "molecular_function": [ { "name": "sulfate transmembrane transporter activity", "id": "GO:0015116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015116", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "thiosulfate transmembrane transporter activity", "id": "GO:0015117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015117", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "oxaloacetate transmembrane transporter activity", "id": "GO:0015131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015131", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "malate transmembrane transporter activity", "id": "GO:0015140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015140", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" }, { "name": "succinate transmembrane transporter activity", "id": "GO:0015141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015141", "evidence": [ { "database": "UniProtKB", "id": "Q9VHG7", "url": "https://www.uniprot.org/uniprotkb/Q9VHG7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VHG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHG8", "url": "https://www.uniprot.org/uniprotkb/Q9VHG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 51012.0, "gene_names": "Dmel\\CG16734;CG16734;Dmel\\CG16734;Dmel_CG16734", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VHM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 346, "chemical_mass": 40730.0, "gene_names": "ranshi;CG9793;Dmel\\CG9793;Dmel_CG9793;ranshi", "protein_name": "", "disease": [], "biological_process": [ { "name": "oocyte differentiation", "id": "GO:0009994", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009994", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "germarium-derived oocyte differentiation", "id": "GO:0030706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030706", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" } ], "cellular_component": [ { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "Q9VHM4", "url": "https://www.uniprot.org/uniprotkb/Q9VHM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VHU7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 490, "chemical_mass": 55989.0, "gene_names": "CG7553;CG15864;CG7553;Dmel\\CG15864;Dmel_CG15864", "protein_name": "procollagen-proline 4-dioxygenase", "disease": [], "molecular_function": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q9VHU7", "url": "https://www.uniprot.org/uniprotkb/Q9VHU7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VHV9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VHV9", "url": "https://www.uniprot.org/uniprotkb/Q9VHV9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 536, "chemical_mass": 58823.0, "gene_names": "Dmel\\CG7900;CG7900;Dmel\\CG7900;Dmel_CG7900", "protein_name": "Amidase domain-containing protein", "disease": [ { "disease_id": "DOID:0060367", "name": "Parkinson's disease 1", "description": "A late onset Parkinson's disease that has_material_basis_in mutation in the alpha-synuclein gene on chromosome 4q22.1.", "url": "https://disease-ontology.org/term/DOID:0060367", "evidence": [ { "id": "0060367", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060367" } ], "weight": 0.0 }, { "disease_id": "DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences.", "url": "https://disease-ontology.org/term/DOID:1574", "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ], "weight": 0.0 }, { "disease_id": "DOID:303", "name": "substance-related disorder", "description": "A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning.", "url": "https://disease-ontology.org/term/DOID:303", "evidence": [ { "id": "303", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:303" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 }, { "disease_id": "DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine.", "url": "https://disease-ontology.org/term/DOID:9975", "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "fatty acid amide hydrolase activity", "id": "GO:0017064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017064", "evidence": [ { "database": "UniProtKB", "id": "Q9VHV9", "url": "https://www.uniprot.org/uniprotkb/Q9VHV9" } ], "pmid": "" }, { "name": "monoacylglycerol lipase activity", "id": "GO:0047372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "Q9VHV9", "url": "https://www.uniprot.org/uniprotkb/Q9VHV9" } ], "pmid": "" } ], "biological_process": [ { "name": "fatty acid catabolic process", "id": "GO:0009062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009062", "evidence": [ { "database": "UniProtKB", "id": "Q9VHV9", "url": "https://www.uniprot.org/uniprotkb/Q9VHV9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VI35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VI35", "url": "https://www.uniprot.org/uniprotkb/Q9VI35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 195, "chemical_mass": 22321.0, "gene_names": "CG2337;CG2337;CG31482;Dmel\\CG31482;Dmel_CG31482", "protein_name": "SCP domain-containing protein", "disease": [ { "disease_id": "DOID:3498", "name": "pancreatic ductal adenocarcinoma", "description": "A pancreatic adenocarcinoma that derives_from pancreatic duct cells.", "url": "https://disease-ontology.org/term/DOID:3498", "evidence": [ { "id": "3498", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3498" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VI35", "url": "https://www.uniprot.org/uniprotkb/Q9VI35" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VI35", "url": "https://www.uniprot.org/uniprotkb/Q9VI35" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VI49-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VI49", "url": "https://www.uniprot.org/uniprotkb/Q9VI49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1047, "chemical_mass": 115206.0, "gene_names": "BcDNA:GH19145;BG:DS00464.1;BcDNA:GH19145;CG1979;Dmel\\CG1979;Dmel_CG1979", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VI69-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VI69", "url": "https://www.uniprot.org/uniprotkb/Q9VI69" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 147, "chemical_mass": 17096.0, "gene_names": "Dmel\\CG14610;CG14610;Dmel\\CG14610;Dmel_CG14610", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VIG0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 347, "chemical_mass": 39253.0, "gene_names": "Dmel\\CG9257;CG9257;Dmel\\CG9257;Dmel_CG9257", "protein_name": "Malectin domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "pmid": "" } ], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VIG0", "url": "https://www.uniprot.org/uniprotkb/Q9VIG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VIH0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 388, "chemical_mass": 43511.0, "gene_names": "Nthl1;9272;CG9272;Dmel\\CG9272;Dmel_CG9272;NTH1;NTHL1;Nth1;Nthl1", "protein_name": "Endonuclease III homolog", "disease": [ { "disease_id": "DOID:0080411", "name": "familial adenomatous polyposis 3", "description": "A familial adenomatous polyposis that has_material_basis_in homozygous or compound heterozygous mutation in the NTHL1 gene on chromosome 16p13.", "url": "https://disease-ontology.org/term/DOID:0080411", "evidence": [ { "id": "0080411", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080411" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "class I DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0140078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140078", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity", "id": "GO:0000703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000703", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" } ], "biological_process": [ { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" }, { "name": "base-excision repair, AP site formation", "id": "GO:0006285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006285", "evidence": [ { "database": "UniProtKB", "id": "Q9VIH0", "url": "https://www.uniprot.org/uniprotkb/Q9VIH0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VIK3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIK3", "url": "https://www.uniprot.org/uniprotkb/Q9VIK3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 448, "chemical_mass": 51013.0, "gene_names": "Dmel\\CG9316;38E.9;CG9316;Dmel\\CG9316;Dmel_CG9316;FBXL10", "protein_name": "F-box domain-containing protein", "disease": [], "cellular_component": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK3", "url": "https://www.uniprot.org/uniprotkb/Q9VIK3" } ], "pmid": "" } ], "biological_process": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q9VIK3", "url": "https://www.uniprot.org/uniprotkb/Q9VIK3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VIL6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VIL6", "url": "https://www.uniprot.org/uniprotkb/Q9VIL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 233, "chemical_mass": 26176.0, "gene_names": "38D.19;38D.19;CG15475;Dmel\\CG15475;Dmel_CG15475", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VJC8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJC8", "url": "https://www.uniprot.org/uniprotkb/Q9VJC8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 206, "chemical_mass": 22514.0, "gene_names": "Dmel\\CG15142;CG15142;Dmel\\CG15142;Dmel_CG15142", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC8", "url": "https://www.uniprot.org/uniprotkb/Q9VJC8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VJC8", "url": "https://www.uniprot.org/uniprotkb/Q9VJC8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VJU2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 224, "chemical_mass": 25270.0, "gene_names": "NimC3;BG:DS05899.2;CG16880;Dmel\\CG16880;Dmel_CG16880;I(2)34Fa;NimC3;br30;l(2)34Fa;l(2)br30;l(2)k00811;l34Fa;nimC3", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "pmid": "" } ], "biological_process": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "Q9VJU2", "url": "https://www.uniprot.org/uniprotkb/Q9VJU2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VJW0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VJW0", "url": "https://www.uniprot.org/uniprotkb/Q9VJW0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 169, "chemical_mass": 19510.0, "gene_names": "Dmel\\CG16888;CG16888;Dmel\\CG16888;Dmel_CG16888", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VK49-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VK49", "url": "https://www.uniprot.org/uniprotkb/Q9VK49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 282, "chemical_mass": 32180.0, "gene_names": "Dmel\\CG16800;CG16800;Dmel\\CG16800;Dmel_CG16800", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VKA3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 701, "chemical_mass": 78092.0, "gene_names": "ZnT33D;CG17215;CG31860;Dmel\\CG31860;Dmel_CG31860;ZNT33D;ZnT33D;cg31860;dZnT33D", "protein_name": "", "disease": [ { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 } ], "biological_process": [ { "name": "detoxification of zinc ion", "id": "GO:0010312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010312", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "zinc ion transmembrane transport", "id": "GO:0071577", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071577", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "zinc ion transport", "id": "GO:0006829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006829", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "response to zinc ion", "id": "GO:0010043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010043", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "intracellular zinc ion homeostasis", "id": "GO:0006882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006882", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion transmembrane transporter activity", "id": "GO:0005385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005385", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "Q9VKA3", "url": "https://www.uniprot.org/uniprotkb/Q9VKA3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VKE6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKE6", "url": "https://www.uniprot.org/uniprotkb/Q9VKE6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 584, "chemical_mass": 67250.0, "gene_names": "Mal-B1;CG14934;Dmel\\CG14934;Dmel_CG14934;Drome_B1;Mal-B1;mal_B1", "protein_name": "alpha-glucosidase", "disease": [ { "disease_id": "DOID:9266", "name": "cystinuria", "description": "An amino acid metabolic disorder that involves the formation of cystine stones in the kidneys, ureter, and bladder.", "url": "https://disease-ontology.org/term/DOID:9266", "evidence": [ { "id": "9266", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9266" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "alpha-1,4-glucosidase activity", "id": "GO:0004558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004558", "evidence": [ { "database": "UniProtKB", "id": "Q9VKE6", "url": "https://www.uniprot.org/uniprotkb/Q9VKE6" } ], "pmid": "" } ], "biological_process": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q9VKE6", "url": "https://www.uniprot.org/uniprotkb/Q9VKE6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VKH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1931, "chemical_mass": 221829.0, "gene_names": "cana;CENP-E ana;CENPana;CG32955;CG33694;CG4831;CP15516;Cana;Cenp-E;Cenp_E;DmCana;Dmel\\CG33694;Dmel_CG33694;KIF 10;KIF10;cana;l(2)k07716", "protein_name": "", "disease": [ { "disease_id": "DOID:0070283", "name": "primary autosomal recessive microcephaly 13", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the CENPE gene on chromosome 4q24.", "url": "https://disease-ontology.org/term/DOID:0070283", "evidence": [ { "id": "0070283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070283" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "plus-end-directed microtubule motor activity", "id": "GO:0008574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008574", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q9VKH9", "url": "https://www.uniprot.org/uniprotkb/Q9VKH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VKH9-1", "start_pos": "1884", "end_pos": "1884", "site_lbl": "Thr1884", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1884, "start_aa": "Thr", "end_pos": 1884, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1884", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VKR1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 281, "chemical_mass": 31707.0, "gene_names": "Dmel\\CG17118;CG17118;Dmel\\CG17118;Dmel_CG17118", "protein_name": "CFA20 domain-containing protein", "disease": [], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" }, { "name": "positive regulation of cell motility", "id": "GO:2000147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000147", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency involved in ciliary motility", "id": "GO:0060296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060296", "evidence": [ { "database": "UniProtKB", "id": "Q9VKR1", "url": "https://www.uniprot.org/uniprotkb/Q9VKR1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VL26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL26", "url": "https://www.uniprot.org/uniprotkb/Q9VL26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 183, "chemical_mass": 21384.0, "gene_names": "BcDNA:LD02427;BcDNA:LD02427;CG5727;Dmel\\CG5727;Dmel_CG5727", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VL47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL47", "url": "https://www.uniprot.org/uniprotkb/Q9VL47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 734, "chemical_mass": 84400.0, "gene_names": "Dmel\\CG13127;CG13127;Dmel\\CG13127;Dmel_CG13127", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VL77-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 10725.0, "gene_names": "Dmel\\CG4537;CG4537;Dmel\\CG4537;Dmel_CG4537", "protein_name": "Cysteine-rich PDZ-binding protein", "disease": [ { "disease_id": "DOID:2732", "name": "Rothmund-Thomson syndrome", "description": "A skin disease characterized by poikiloderma, congenital bone defects, and an increased risk of osteosarcoma in childhood and skin cancer later in life that has_material_basis_in homozygous or compound heterozygous mutation in the DNA helicase gene RECQL4 on chromosome 8q24.", "url": "https://disease-ontology.org/term/DOID:2732", "evidence": [ { "id": "2732", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2732" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "Q9VL77", "url": "https://www.uniprot.org/uniprotkb/Q9VL77" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VLB4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLB4", "url": "https://www.uniprot.org/uniprotkb/Q9VLB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 328, "chemical_mass": 32588.0, "gene_names": "CG17022;CG17022;CG31883;Dmel\\CG31883;Dmel_CG31883;anon-WO0140519.218", "protein_name": "", "disease": [], "biological_process": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VLB4", "url": "https://www.uniprot.org/uniprotkb/Q9VLB4" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VLB4", "url": "https://www.uniprot.org/uniprotkb/Q9VLB4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VLB4-1", "start_pos": "66", "end_pos": "66", "site_lbl": "Thr66", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VLB4-1", "start_pos": "79", "end_pos": "79", "site_lbl": "Thr79", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VLB4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VLB4" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VLG0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 146, "chemical_mass": 16456.0, "gene_names": "Dmel\\CG18662;CG18662;Dmel\\CG18662;Dmel_CG18662", "protein_name": "Sex-regulated protein janus-B", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "pmid": "" } ], "biological_process": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein histidine phosphatase activity", "id": "GO:0101006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101006", "evidence": [ { "database": "UniProtKB", "id": "Q9VLG0", "url": "https://www.uniprot.org/uniprotkb/Q9VLG0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VLH6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLH6", "url": "https://www.uniprot.org/uniprotkb/Q9VLH6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 250, "chemical_mass": 27440.0, "gene_names": "CG18663;CG18663;CG32983;Dmel\\CG32983;Dmel_CG32983", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VLL6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLL6", "url": "https://www.uniprot.org/uniprotkb/Q9VLL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 284, "chemical_mass": 29225.0, "gene_names": "Dmel\\CG13386;CG13386;Dmel\\CG13386;Dmel_CG13386", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VLN0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 381, "chemical_mass": 41475.0, "gene_names": "Dmel\\CG13390;CG13390;Dmel\\CG13390;Dmel_CG13390", "protein_name": "Mitochondrial ribosome-associated GTPase 2", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "Q9VLN0", "url": "https://www.uniprot.org/uniprotkb/Q9VLN0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VLU9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VLU9", "url": "https://www.uniprot.org/uniprotkb/Q9VLU9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 358, "chemical_mass": 39925.0, "gene_names": "Dmel\\CG7231;CG7231;Dmel\\CG7231;Dmel_CG7231", "protein_name": "Menorin-like domain-containing protein", "disease": [ { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VLU9", "url": "https://www.uniprot.org/uniprotkb/Q9VLU9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VM54-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM54", "url": "https://www.uniprot.org/uniprotkb/Q9VM54" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 359, "chemical_mass": 41461.0, "gene_names": "Dmel\\CG43322;CG13776;CG43322;Dmel\\CG43322;Dmel_CG43322", "protein_name": "J domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VME8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 504, "chemical_mass": 58910.0, "gene_names": "ppk14;CG9501;Dmel\\CG9501;Dmel_CG9501;PPK14;Ppk14;ppk14", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" } ], "biological_process": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" } ], "molecular_function": [ { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "Q9VME8", "url": "https://www.uniprot.org/uniprotkb/Q9VME8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VMK7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMK7", "url": "https://www.uniprot.org/uniprotkb/Q9VMK7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 11730.0, "gene_names": "Dmel\\CG13998;CG13998;Dmel\\CG13998;Dmel_CG13998", "protein_name": "", "disease": [], "biological_process": [ { "name": "vitelline membrane formation involved in chorion-containing eggshell formation", "id": "GO:0007305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007305", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK7", "url": "https://www.uniprot.org/uniprotkb/Q9VMK7" } ], "pmid": "" } ], "cellular_component": [ { "name": "egg chorion", "id": "GO:0042600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042600", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK7", "url": "https://www.uniprot.org/uniprotkb/Q9VMK7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VML2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 3489, "chemical_mass": 389825.0, "gene_names": "bchs;Alfy;BcDNA:SD12984;Bchs;Beach1;CG14001;CG9011;DBEACH1;Dmel\\CG14001;Dmel_CG14001;EP2299;alfy;bchd;bchs;beach", "protein_name": "", "disease": [ { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0070295", "name": "primary autosomal dominant microcephaly 18", "description": "A primary microcephaly that has_material_basis_in heterozygous mutation in the WDFY3 gene on chromosome 4q21.", "url": "https://disease-ontology.org/term/DOID:0070295", "evidence": [ { "id": "0070295", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070295" } ], "weight": 0.0 }, { "disease_id": "DOID:2935", "name": "Chediak-Higashi syndrome", "description": "A syndrome characterized by oculocutaneous albinism, immune deficiency, coagulation deficiency and neuropathy and that has_material_basis_in homozygous or compound heterozygous mutation in the lysosomal trafficking regulator gene (LYST) on chromosome 1q42.", "url": "https://disease-ontology.org/term/DOID:2935", "evidence": [ { "id": "2935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2935" } ], "weight": 0.0 } ], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "positive regulation of organ growth", "id": "GO:0046622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046622", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "fasciculation of motor neuron axon", "id": "GO:0097156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097156", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "regulation of protein ubiquitination", "id": "GO:0031396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031396", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "chaeta development", "id": "GO:0022416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022416", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VML2", "url": "https://www.uniprot.org/uniprotkb/Q9VML2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VML2-1", "start_pos": "2314", "end_pos": "2314", "site_lbl": "Thr2314", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2314, "start_aa": "Thr", "end_pos": 2314, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2314", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VML2-1", "start_pos": "42", "end_pos": "42", "site_lbl": "Thr42", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VMX7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 266, "chemical_mass": 28720.0, "gene_names": "Jon25Bi;25B;CG8867;Dmel\\CG8867;Dmel_CG8867;Jon25Bi;Jon25B;Jon25i;Jon25;SP137;Ser4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "endopeptidase activity", "id": "GO:0004175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004175", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" }, { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX7", "url": "https://www.uniprot.org/uniprotkb/Q9VMX7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VN30-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1079, "chemical_mass": 126895.0, "gene_names": "sac;CG14651;Dmel\\CG14651;Dmel_CG14651;sac", "protein_name": "", "disease": [], "biological_process": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" } ], "cellular_component": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" }, { "name": "dynein complex", "id": "GO:0030286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030286", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" } ], "molecular_function": [ { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" }, { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "Q9VN30", "url": "https://www.uniprot.org/uniprotkb/Q9VN30" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VN42-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN42", "url": "https://www.uniprot.org/uniprotkb/Q9VN42" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 226, "chemical_mass": 25971.0, "gene_names": "Dlip2;CG9771;DIP2;Dip2;Dlip2;Dmel\\CG9771;Dmel_CG9771;dip2;dmDIP2;sip4", "protein_name": "", "disease": [], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VN42", "url": "https://www.uniprot.org/uniprotkb/Q9VN42" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9VN42", "url": "https://www.uniprot.org/uniprotkb/Q9VN42" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VN65-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN65", "url": "https://www.uniprot.org/uniprotkb/Q9VN65" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 97, "chemical_mass": 11965.0, "gene_names": "Dmel\\CG14659;CG14659;Dmel\\CG14659;Dmel_CG14659", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VNF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 438, "chemical_mass": 46379.0, "gene_names": "anon-WO0118547.367;CG12170;Dmel\\CG12170;Dmel_CG12170;anon-WO0118547.367", "protein_name": "3-oxoacyl-[acyl-carrier-protein] synthase", "disease": [], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "pmid": "" } ], "biological_process": [ { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "pmid": "" }, { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "pmid": "" } ], "molecular_function": [ { "name": "3-oxoacyl-[acyl-carrier-protein] synthase activity", "id": "GO:0004315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004315", "evidence": [ { "database": "UniProtKB", "id": "Q9VNF5", "url": "https://www.uniprot.org/uniprotkb/Q9VNF5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VNN0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNN0", "url": "https://www.uniprot.org/uniprotkb/Q9VNN0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 351, "chemical_mass": 38478.0, "gene_names": "Osi10a;10a_CG15593;CG15593;CG46436;Dmel\\CG46436;Dmel_CG46436;Osi10a;Osi10", "protein_name": "", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN0", "url": "https://www.uniprot.org/uniprotkb/Q9VNN0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN0", "url": "https://www.uniprot.org/uniprotkb/Q9VNN0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VNN0-1", "start_pos": "125", "end_pos": "125", "site_lbl": "Thr125", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 125, "start_aa": "Thr", "end_pos": 125, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr125", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VNU3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNU3", "url": "https://www.uniprot.org/uniprotkb/Q9VNU3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 538, "chemical_mass": 64375.0, "gene_names": "Dmel\\CG11449;CG11449;Dmel\\CG11449;Dmel_CG11449", "protein_name": "Cilia- and flagella-associated protein 45", "disease": [ { "disease_id": "DOID:0051025", "name": "visceral heterotaxy 11", "description": "A visceral heterotaxy that is characterized by a failure to generate normal left-right visceral asymmetry during embryogenesis, which can result in heterotaxy syndrome or situs inversus totalis and that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP45 gene on chromosome 1q23.", "url": "https://disease-ontology.org/term/DOID:0051025", "evidence": [ { "id": "0051025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051025" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU3", "url": "https://www.uniprot.org/uniprotkb/Q9VNU3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VNU3-1", "start_pos": "103", "end_pos": "103", "site_lbl": "Thr103", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VNU3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VNU3" } ] } ] }, { "uniprot_canonical_ac": "Q9VNU3-1", "start_pos": "105", "end_pos": "105", "site_lbl": "Ser105", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 105, "start_aa": "Ser", "end_pos": 105, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser105", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VNU3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VNU3" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VNY9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNY9", "url": "https://www.uniprot.org/uniprotkb/Q9VNY9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 192, "chemical_mass": 20819.0, "gene_names": "Dmel\\CG14573;CG14573;Dmel\\CG14573;Dmel_CG14573", "protein_name": "DUF4794 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VNZ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 642, "chemical_mass": 73674.0, "gene_names": "Pykl5;CG11249;Dmel\\CG11249;Dmel_CG11249", "protein_name": "", "disease": [], "molecular_function": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" }, { "name": "potassium ion binding", "id": "GO:0030955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030955", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" } ], "biological_process": [ { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "Q9VNZ9", "url": "https://www.uniprot.org/uniprotkb/Q9VNZ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPB4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPB4", "url": "https://www.uniprot.org/uniprotkb/Q9VPB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 340, "chemical_mass": 38217.0, "gene_names": "Dmel\\CG3698;CG3698;Dmel\\CG3698;Dmel_CG3698", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPD9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPD9", "url": "https://www.uniprot.org/uniprotkb/Q9VPD9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 504, "chemical_mass": 55360.0, "gene_names": "Dmel\\CG17637;CG17637;Dmel\\CG17637;Dmel_CG17637", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VPD9", "url": "https://www.uniprot.org/uniprotkb/Q9VPD9" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VPD9", "url": "https://www.uniprot.org/uniprotkb/Q9VPD9" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VPD9", "url": "https://www.uniprot.org/uniprotkb/Q9VPD9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4K7E5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7E5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7E5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 110, "chemical_mass": 12730.0, "gene_names": "lincRNA.337;CG43272;Dmel\\CG43272;Dmel_CG43272", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1ZAQ3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 682, "chemical_mass": 79724.0, "gene_names": "CG15612;Dmel\\CG46491;CG15612;CG15613;CG30456;CG46491;Dmel\\CG46491;Dmel_CG46491", "protein_name": "DH domain-containing protein", "disease": [ { "disease_id": "DOID:0061036", "name": "autosomal dominant intellectual developmental disorder 63 with macrocephaly", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in heterozygous mutation in the TRIO gene on chromosome 5p15.", "url": "https://disease-ontology.org/term/DOID:0061036", "evidence": [ { "id": "0061036", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061036" } ], "weight": 0.0 }, { "disease_id": "DOID:0070074", "name": "autosomal dominant intellectual developmental disorder 44", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the TRIO gene on chromosome 5p15.2.", "url": "https://disease-ontology.org/term/DOID:0070074", "evidence": [ { "id": "0070074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070074" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A1ZAQ3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZAQ3-1", "start_pos": "170", "end_pos": "170", "site_lbl": "Thr170", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 170, "start_aa": "Thr", "end_pos": 170, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr170", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4K651-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 784, "chemical_mass": 86177.0, "gene_names": "Best1;Best1;CG6264;Dbest;Dmel\\CG6264;Dmel_CG6264;anon-WO0118547.380;best;dBest1;dbest1;dmBest1", "protein_name": "", "disease": [ { "disease_id": "DOID:0050661", "name": "vitelliform macular dystrophy", "description": "A macular degeneration that it is characterized by the disruption of cells in a small area near the center of the retina, the macula and may cause progressive vision loss.", "url": "https://disease-ontology.org/term/DOID:0050661", "evidence": [ { "id": "0050661", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050661" } ], "weight": 0.0 }, { "disease_id": "DOID:0050662", "name": "bestrophinopathy", "description": "A macular degeneration that is characterized by central vision loss, an absent electrooculogram light rise and a reduced electroretinogram, has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the BEST1 gene on chromosome 11q12.", "url": "https://disease-ontology.org/term/DOID:0050662", "evidence": [ { "id": "0050662", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050662" } ], "weight": 0.0 }, { "disease_id": "DOID:0080685", "name": "aortic dissection", "description": "An aortic disease that is characterized by tearing of the intimal layer of the aorta resulting in separation of the layers of the aortic wall.", "url": "https://disease-ontology.org/term/DOID:0080685", "evidence": [ { "id": "0080685", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080685" } ], "weight": 0.0 }, { "disease_id": "DOID:0110396", "name": "retinitis pigmentosa 50", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the BEST1 gene on chromosome 11q13.", "url": "https://disease-ontology.org/term/DOID:0110396", "evidence": [ { "id": "0110396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110396" } ], "weight": 0.0 }, { "disease_id": "DOID:0111569", "name": "autosomal dominant vitreoretinochoroidopathy", "description": "A hereditary retinal dystrophy characterized by abnormal chorioretinal hypopigmentation and hyperpigmentation typically lying between the vortex veins and the ora serrata for 360 degrees and other ocular developmental anomalies that has_material_basis_in heterozygous mutation in the BEST1 gene on chromosome 11q12.3.", "url": "https://disease-ontology.org/term/DOID:0111569", "evidence": [ { "id": "0111569", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111569" } ], "weight": 0.0 }, { "disease_id": "DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss.", "url": "https://disease-ontology.org/term/DOID:4448", "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "volume-sensitive chloride channel activity", "id": "GO:0072320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072320", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" } ], "biological_process": [ { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "chloride transport", "id": "GO:0006821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006821", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "intracellular water homeostasis", "id": "GO:0009992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009992", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" }, { "name": "chloride transmembrane transport", "id": "GO:1902476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902476", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K651", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K651" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4K651-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Thr498", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1Z7I1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 620, "chemical_mass": 71227.0, "gene_names": "Dmel\\CG14744;CG14744;Dmel\\CG14744;Dmel_CG14744", "protein_name": "Sodium/calcium exchanger membrane region domain-containing protein", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "mitochondrial crista", "id": "GO:0030061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030061", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" } ], "biological_process": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "monoatomic cation transport", "id": "GO:0006812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006812", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" } ], "molecular_function": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" }, { "name": "calcium:sodium antiporter activity", "id": "GO:0005432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005432", "evidence": [ { "database": "UniProtKB", "id": "A1Z7I1", "url": "https://www.uniprot.org/uniprotkb/A1Z7I1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1ZAW0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1722, "chemical_mass": 197765.0, "gene_names": "Dcr-2;CG6493;DCR-2;DCR2;DICER-2;DICER;Dcr-2;Dcr2;Dcr;Dicer-II;Dicer2;Dicer;DmDcr-2;Dmel\\CG6493;Dmel_CG6493;cg6493;dDcr2;dcr-2;dcr2;dcr;dic2;dicer-2;dicer2;dicer;dmDcr-2", "protein_name": "Endoribonuclease Dcr-2", "disease": [], "biological_process": [ { "name": "RISC complex assembly", "id": "GO:0070922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070922", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "positive regulation of defense response to virus by host", "id": "GO:0002230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002230", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated post-transcriptional gene silencing", "id": "GO:0035194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035194", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "siRNA processing", "id": "GO:0030422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030422", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "cellular response to virus", "id": "GO:0098586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098586", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "positive regulation of innate immune response", "id": "GO:0045089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045089", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "detection of virus", "id": "GO:0009597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009597", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "RNAi-mediated antiviral immune response", "id": "GO:0009616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009616", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "dosage compensation by hyperactivation of X chromosome", "id": "GO:0009047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009047", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "positive regulation of Toll signaling pathway", "id": "GO:0045752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045752", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "global gene silencing by mRNA cleavage", "id": "GO:0098795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098795", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "lncRNA catabolic process", "id": "GO:0110064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110064", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "siRNA binding", "id": "GO:0035197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035197", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "ribonuclease III activity", "id": "GO:0004525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004525", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "deoxyribonuclease I activity", "id": "GO:0004530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004530", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on RNA", "id": "GO:0008186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008186", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "RISC complex", "id": "GO:0016442", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016442", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" }, { "name": "RISC-loading complex", "id": "GO:0070578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070578", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1566", "end_pos": "1566", "site_lbl": "Thr1566", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1566, "start_aa": "Thr", "end_pos": 1566, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1566", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1210", "end_pos": "1210", "site_lbl": "Glu1210", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "V", "comment": "No effect on RNAi silencing activity.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1217", "end_pos": "1217", "site_lbl": "Asp1217", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Unable to unwind blunt termini (BLT) dsRNAs and fails to rescue loss of RNA silencing activity in mutants. No effect on binding to BLT or 3' overhanging (3'ovr) termini dsRNAs; when associated with A-1476. No effect on binding to 3' overhanging (3'ovr) termini but abolishes binding to BLT dsRNAs; when associated with A-34 and A-1476.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "25891075", "url": "https://glygen.org/publication/PubMed/25891075" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1237", "end_pos": "1237", "site_lbl": "Glu1237", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "No effect on RNAi silencing activity.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1330", "end_pos": "1330", "site_lbl": "Arg1330", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Loss of dimerization, likely affecting formation of the initial binding complex with loqs and dsRNA.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "35768513", "url": "https://glygen.org/publication/PubMed/35768513" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1371", "end_pos": "1371", "site_lbl": "Glu1371", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Loss of RNAi silencing activity. Decreased processing of dsRNAs into SiRNAs. No effect on mRNA cleavage.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1476", "end_pos": "1476", "site_lbl": "Asp1476", "weight": 0.0, "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Unable to unwind blunt termini (BLT) dsRNAs and fails to rescue loss of RNA silencing activity in mutants. No effect on binding to BLT or 3' overhanging (3'ovr) termini dsRNAs; when associated with A-1217. No effect on binding to 3' overhanging (3'ovr) termini but abolishes binding to BLT dsRNAs; when associated with A-34 and A-1217.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "25891075", "url": "https://glygen.org/publication/PubMed/25891075" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "1617", "end_pos": "1617", "site_lbl": "Glu1617", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Loss of RNAi silencing activity. Decreased processing of dsRNAs into SiRNAs. No effect on mRNA cleavage.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "173", "end_pos": "173", "site_lbl": "Gly173", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Decreased production of siRNAs from dsRNA precursors.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "225", "end_pos": "225", "site_lbl": "Phe225", "weight": 0.0, "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "G", "comment": "Reduced RNAi activity due to decreased generation of siRNAs from endogenous and viral dsRNAs. In vitro, abolishes ATP-dependent cleavage of blunt termini (BLT) dsRNAs but has no effect on ATP-independent cleavage of 3' overhanging (3'ovr) termini dsRNAs. Decreased binding affinities for BLT and 3'ovr dsRNAs. Binding affinity for BLT dsRNAs is further decreased by addition of ATP. Also displays severely reduced binding to loqs (isoform PD). No effect on ATP hydrolysis. Abolishes binding to BLT and 3'ovr dsRNAs; when associated with A-493 and A-596.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "31", "end_pos": "31", "site_lbl": "Gly31", "weight": 0.0, "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "R", "comment": "Disrupts ATP binding and thus ATP hydrolysis. Also effects binding to dsRNA substrates and siRNA unwinding by the RISC-loading complex is decreased. Severely reduced RNAi activity due to decreased generation of siRNAs from endogenous and viral dsRNAs. Abolishes ATP-dependent cleavage of blunt termini (BLT) dsRNAs but has no effect on ATP-independent cleavage of 3' overhanging (3'ovr) termini dsRNAs. Decreased binding affinities for BLT and 3'ovr dsRNAs. Also reduces binding to loqs. Fails to rescue loss of RNA silencing activity in mutants.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "21419681", "url": "https://glygen.org/publication/PubMed/21419681" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" }, { "database": "PubMed", "id": "15550672", "url": "https://glygen.org/publication/PubMed/15550672" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" }, { "database": "PubMed", "id": "15066283", "url": "https://glygen.org/publication/PubMed/15066283" }, { "database": "PubMed", "id": "34590626", "url": "https://glygen.org/publication/PubMed/34590626" }, { "database": "PubMed", "id": "24488111", "url": "https://glygen.org/publication/PubMed/24488111" }, { "database": "PubMed", "id": "34257295", "url": "https://glygen.org/publication/PubMed/34257295" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "324", "end_pos": "324", "site_lbl": "Arg324", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Decreased binding to r2d2.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "331", "end_pos": "331", "site_lbl": "Glu331", "weight": 0.0, "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "R", "comment": "Decreased binding to r2d2.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Lys34", "weight": 0.0, "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "ATPase-defective. Unable to unwind blunt termini (BLT) dsRNAs but is able to bind BLT dsRNAs. No effect on binding to 3' overhanging (3'ovr) termini but abolishes binding to BLT dsRNAs; when associated with A-1217 and A-1476.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "25891075", "url": "https://glygen.org/publication/PubMed/25891075" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "500", "end_pos": "500", "site_lbl": "Ala500", "weight": 0.0, "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "V", "comment": "Increased viral replication of the Sindbis virus (SINV).", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "24009507", "url": "https://glygen.org/publication/PubMed/24009507" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "743", "end_pos": "743", "site_lbl": "His743", "weight": 0.0, "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Partially rescues RNA silencing activity in mutants. Abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-752, A-759, A-943 and A-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "752", "end_pos": "752", "site_lbl": "Arg752", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. Partially rescues RNA silencing activity in mutants. Abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-743, A-759, A-943 and A-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "759", "end_pos": "759", "site_lbl": "Arg759", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. Partially rescues RNA silencing activity in mutants. Abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-743, A-752, A-943 and A-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" }, { "database": "PubMed", "id": "35768503", "url": "https://glygen.org/publication/PubMed/35768503" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "943", "end_pos": "943", "site_lbl": "Arg943", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. However, has no effect on RNA cleavage rates, when associated with A-956. Decreased siRNA length fidelity, partially rescues RNA silencing activity in mutants and abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-743, A-752, A-759 and A-956. Abolishes binding to BLT and 3'ovr dsRNAs; when associated with G-225 and A-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] }, { "sequence_org": "R", "sequence_mut": "E", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. However, has no effect on RNA cleavage rates, when associated with E-956.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] } ] }, { "uniprot_canonical_ac": "A1ZAW0-1", "start_pos": "956", "end_pos": "956", "site_lbl": "Arg956", "weight": 0.0, "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. However, has no effect on RNA cleavage rates when associated with A-943. Partially rescues RNA silencing activity in mutants. Abolishes cleavage of 3' overhanging (3'ovr) termini dsRNAs but has no effect on cleavage of blunt termini (BLT) dsRNAs, when associated with A-743, A-752, A-759 and A-943. Abolishes binding to BLT and 3'ovr dsRNAs; when associated with G-225 and A-493.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "29269422", "url": "https://glygen.org/publication/PubMed/29269422" }, { "database": "PubMed", "id": "32843367", "url": "https://glygen.org/publication/PubMed/32843367" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] }, { "sequence_org": "R", "sequence_mut": "E", "comment": "Decreased siRNA length fidelity. Abundance of 21-nucleotide siRNAs produced by the enzyme is decreased whereas the abundance of both 20- and 22-nucleotide siRNAs is increased. However, has no effect on RNA cleavage rates, when associated with E-943.", "evidence": [ { "database": "UniProtKB", "id": "A1ZAW0", "url": "https://www.uniprot.org/uniprotkb/A1ZAW0" }, { "database": "PubMed", "id": "27872309", "url": "https://glygen.org/publication/PubMed/27872309" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A126GUN8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 760, "chemical_mass": 83489.0, "gene_names": "Klp54D;CG15844;CG43323;DmKlp54D;Dmel\\CG43323;Dmel_CG43323;KIF 12;KIF12;KLP1;KLP54D;Klp1;Klp54D", "protein_name": "Kinesin-like protein", "disease": [ { "disease_id": "DOID:0070221", "name": "progressive familial intrahepatic cholestasis", "description": "An intrahepatic cholestasis characterized by early onset of chronic unremitting cholestasis of hepatocellular origin that progresses to hepatic fibrosis, cirrhosis, and end-stage liver disease before adulthood.", "url": "https://disease-ontology.org/term/DOID:0070221", "evidence": [ { "id": "0070221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070221" } ], "weight": 0.0 }, { "disease_id": "DOID:0080547", "name": "metabolic dysfunction-associated steatohepatitis", "description": "A metabolic dysfunction-associated steatotic liver disease characterized by the presence of inflammation with hepatocyte injury such as ballooning, with or without fibrosis.", "url": "https://disease-ontology.org/term/DOID:0080547", "evidence": [ { "id": "0080547", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080547" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" } ], "cellular_component": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" }, { "name": "kinesin complex", "id": "GO:0005871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005871", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" } ], "biological_process": [ { "name": "microtubule-based movement", "id": "GO:0007018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007018", "evidence": [ { "database": "UniProtKB", "id": "A0A126GUN8", "url": "https://www.uniprot.org/uniprotkb/A0A126GUN8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A126GUN8-1", "start_pos": "666", "end_pos": "666", "site_lbl": "Thr666", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 666, "start_aa": "Thr", "end_pos": 666, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr666", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4K6N2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 520, "chemical_mass": 59473.0, "gene_names": "FoxP;CG16899;CG32937;CG43067;DmFoxP;Dmcg16899;Dmel\\CG43067;Dmel_CG43067;FoxP;dFoxP;fd85E", "protein_name": "", "disease": [ { "disease_id": "DOID:0050200", "name": "Korean hemorrhagic fever", "description": "A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Hantaan virus, which is transmitted_by the eurasian field mouse, Apodemus agrarius, or has_material_basis_in Seoul virus, which is transmitted_by norwegian rat, Rattus norvegicus. The infection has_symptom headache, has_symptom back pain, has_symptom abdominal pain, has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom blurred vision, has_symptom flushing of the face, has_symptom redness of the eyes, has_symptom rash, has_symptom low blood pressure, has_symptom acute shock, has_symptom vascular leakage, and has_symptom acute kidney failure, which can cause severe fluid overload.", "url": "https://disease-ontology.org/term/DOID:0050200", "evidence": [ { "id": "0050200", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050200" } ], "weight": 0.0 }, { "disease_id": "DOID:0050523", "name": "adult T-cell leukemia/lymphoma", "description": "A T-cell acute leukemia that results_in abnormal increase of lymphocytes, derives_from T-cells, has_material_basis_in human T-cell leukemia virus type 1 (Deltaretrovirus priTlym1), which is transmitted_by sexual contact, transmitted_by contaminated needles used by intravenous-drug users, and transmitted_by breast feeding. The infection results_in_formation_of skin lesions.", "url": "https://disease-ontology.org/term/DOID:0050523", "evidence": [ { "id": "0050523", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050523" } ], "weight": 0.0 }, { "disease_id": "DOID:0060038", "name": "specific developmental disorder", "description": "A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination.", "url": "https://disease-ontology.org/term/DOID:0060038", "evidence": [ { "id": "0060038", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060038" } ], "weight": 0.0 }, { "disease_id": "DOID:0060041", "name": "autism spectrum disorder", "description": "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.", "url": "https://disease-ontology.org/term/DOID:0060041", "evidence": [ { "id": "0060041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060041" } ], "weight": 0.0 }, { "disease_id": "DOID:0081267", "name": "graft-versus-host disease", "description": "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.", "url": "https://disease-ontology.org/term/DOID:0081267", "evidence": [ { "id": "0081267", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081267" } ], "weight": 0.0 }, { "disease_id": "DOID:0090110", "name": "immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome", "description": "An autoimmune disease that is characterized by onset in infancy of refractory diarrhea, endocrinopathies, type 1 diabetes mellitus, and dermatitis that has_material_basis_in X-linked recessive mutation in the forkhead box P3 (FOXP3) gene on chromosome Xp11.", "url": "https://disease-ontology.org/term/DOID:0090110", "evidence": [ { "id": "0090110", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090110" } ], "weight": 0.0 }, { "disease_id": "DOID:0090131", "name": "complex cortical dysplasia with other brain malformations", "description": "A brain disease characterized by aberrant neuronal migration and disturbed axonal guidance resulting in variable brain malformations.", "url": "https://disease-ontology.org/term/DOID:0090131", "evidence": [ { "id": "0090131", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090131" } ], "weight": 0.0 }, { "disease_id": "DOID:0111275", "name": "speech-language disorder-1", "description": "A speech disorder characterized by severe orofacial dyspraxia resulting in largely incomprehensible speech that has_material_basis_in heterozygous mutation in FOXP2 on 7q31.1.", "url": "https://disease-ontology.org/term/DOID:0111275", "evidence": [ { "id": "0111275", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111275" } ], "weight": 0.0 }, { "disease_id": "DOID:0111331", "name": "intellectual disability-severe speech delay-mild dysmorphism syndrome", "description": "A syndromic intellectual disability characterized by global developmental delay with moderate to severe speech delay, dysmorphic craniofacial features, and gross motor skill delays that particularly affects expressive speech that has_material_basis_in heterozygous mutation in the FOXP1 gene on chromosome 3p13.", "url": "https://disease-ontology.org/term/DOID:0111331", "evidence": [ { "id": "0111331", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111331" } ], "weight": 0.0 }, { "disease_id": "DOID:106", "name": "pleural tuberculosis", "description": "An extrapulmonary tuberculosis that results_in lymphocyte-predominant exudative pleural effusion, located_in pleura. This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac.", "url": "https://disease-ontology.org/term/DOID:106", "evidence": [ { "id": "106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:106" } ], "weight": 0.0 }, { "disease_id": "DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries.", "url": "https://disease-ontology.org/term/DOID:10763", "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ], "weight": 0.0 }, { "disease_id": "DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age.", "url": "https://disease-ontology.org/term/DOID:1094", "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ], "weight": 0.0 }, { "disease_id": "DOID:11166", "name": "Human papillomavirus infectious disease", "description": "A viral infectious disease that has_material_basis_in human papillomaviruses, which establish productive infections only in the stratified epithelium of the skin or mucous membranes. These viruses cause warts and sometimes tumors. They are transmitted_by sexual contact.", "url": "https://disease-ontology.org/term/DOID:11166", "evidence": [ { "id": "11166", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11166" } ], "weight": 0.0 }, { "disease_id": "DOID:11168", "name": "anogenital venereal wart", "description": "A viral infectious disease that results_in infection located_in skin of vagina, cervix, uterus, anus, penis, scrotum, mouth, or throat, has_material_basis_in human papillomaviruses (types 6 and 11), which are transmitted_by direct contact with the skin during oral, genital, or anal sex with an infected partner. The infection has_symptom anogenital warts.", "url": "https://disease-ontology.org/term/DOID:11168", "evidence": [ { "id": "11168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11168" } ], "weight": 0.0 }, { "disease_id": "DOID:11263", "name": "chlamydia", "description": "A commensal bacterial infectious disease that is caused by Chlamydia trachomatis.", "url": "https://disease-ontology.org/term/DOID:11263", "evidence": [ { "id": "11263", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11263" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:1255", "name": "trichostrongyloidiasis", "description": "A parasitic helminthiasis infectious disease that involves parasitic infection of animals and humans by nematodes of the superfamily Trichostrongyloidea.", "url": "https://disease-ontology.org/term/DOID:1255", "evidence": [ { "id": "1255", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1255" } ], "weight": 0.0 }, { "disease_id": "DOID:12849", "name": "autistic disorder", "description": "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years.", "url": "https://disease-ontology.org/term/DOID:12849", "evidence": [ { "id": "12849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12849" } ], "weight": 0.0 }, { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 }, { "disease_id": "DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone.", "url": "https://disease-ontology.org/term/DOID:1459", "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ], "weight": 0.0 }, { "disease_id": "DOID:1470", "name": "major depressive disorder", "description": "A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.", "url": "https://disease-ontology.org/term/DOID:1470", "evidence": [ { "id": "1470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1470" } ], "weight": 0.0 }, { "disease_id": "DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth.", "url": "https://disease-ontology.org/term/DOID:1682", "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ], "weight": 0.0 }, { "disease_id": "DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.", "url": "https://disease-ontology.org/term/DOID:1883", "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ], "weight": 0.0 }, { "disease_id": "DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice.", "url": "https://disease-ontology.org/term/DOID:2043", "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ], "weight": 0.0 }, { "disease_id": "DOID:2799", "name": "bronchiolitis obliterans", "description": "A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults.", "url": "https://disease-ontology.org/term/DOID:2799", "evidence": [ { "id": "2799", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2799" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:289", "name": "endometriosis", "description": "A female reproductive system disease characterized by the growth of endometrial tissue outside the uterine body.", "url": "https://disease-ontology.org/term/DOID:289", "evidence": [ { "id": "289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:289" } ], "weight": 0.0 }, { "disease_id": "DOID:2938", "name": "Epstein-Barr virus infectious disease", "description": "A viral infectious disease that has_material_basis_in Human gammaherpesvirus 4 (Lymphocryptovirus humangamma4).", "url": "https://disease-ontology.org/term/DOID:2938", "evidence": [ { "id": "2938", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2938" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:321", "name": "HTLV-1-associated myelopathy/tropical spastic paraparesis", "description": "A viral infectious disease that results in inflammation located in spinal cord, has_material_basis_in human T-cell leukemia virus type 1 (Deltaretrovirus priTlym1), which is transmitted by sexual contact, and transmitted by breast feeding. The infection has symptom spastic weakness of both legs, has symptom muscle stiffness, has symptom sensory disturbance, and has symptom spasms.", "url": "https://disease-ontology.org/term/DOID:321", "evidence": [ { "id": "321", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:321" } ], "weight": 0.0 }, { "disease_id": "DOID:3744", "name": "cervical squamous cell carcinoma", "description": "A cervix carcinoma that has_material_basis_in squamous cells of the cervix.", "url": "https://disease-ontology.org/term/DOID:3744", "evidence": [ { "id": "3744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3744" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:401", "name": "multidrug-resistant tuberculosis", "description": "A tuberculosis that is resistant to isoniazid and rifampicin, the two most powerful first-line anti-TB drugs.", "url": "https://disease-ontology.org/term/DOID:401", "evidence": [ { "id": "401", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:401" } ], "weight": 0.0 }, { "disease_id": "DOID:4166", "name": "syphilis", "description": "A primary bacterial infectious disease that is a sexually transmitted systemic disease, has_material_basis_in Treponema pallidum subsp pallidum, which is transmitted_by sexual contact, transmitted_by blood product transfusion, transmitted_by congenital method from mother to fetus or transmitted_by contact with infectious lesions. If left untreated, produces chancres, rashes, and systemic lesions in a clinical course with three stages continued over many years.", "url": "https://disease-ontology.org/term/DOID:4166", "evidence": [ { "id": "4166", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4166" } ], "weight": 0.0 }, { "disease_id": "DOID:4186", "name": "articulation disorder", "description": "A speech disorder that involves mispronouncing speech sounds by omitting, distorting, substituting, or adding sounds which can make speech difficult to understand.", "url": "https://disease-ontology.org/term/DOID:4186", "evidence": [ { "id": "4186", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4186" } ], "weight": 0.0 }, { "disease_id": "DOID:4428", "name": "dyslexia", "description": "A reading disorder resulting from a developmental reading disability involving the inability to process graphic symbols resulting in impairment of reading ability.", "url": "https://disease-ontology.org/term/DOID:4428", "evidence": [ { "id": "4428", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4428" } ], "weight": 0.0 }, { "disease_id": "DOID:4914", "name": "esophagus adenocarcinoma", "description": "An esophageal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:4914", "evidence": [ { "id": "4914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4914" } ], "weight": 0.0 }, { "disease_id": "DOID:4928", "name": "intrahepatic cholangiocarcinoma", "description": "A cholangiocarcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree.", "url": "https://disease-ontology.org/term/DOID:4928", "evidence": [ { "id": "4928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4928" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:8283", "name": "peritonitis", "description": "A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.", "url": "https://disease-ontology.org/term/DOID:8283", "evidence": [ { "id": "8283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8283" } ], "weight": 0.0 }, { "disease_id": "DOID:8568", "name": "infectious mononucleosis", "description": "A viral infectious disease that results in inflammation, located in pharynx, has_material_basis_in Human herpesvirus 4 (Lymphocryptovirus humangamma4) and has symptom fever, has symptom fatigue, has symptom lymphadenopathy, and has symptom splenomegaly.", "url": "https://disease-ontology.org/term/DOID:8568", "evidence": [ { "id": "8568", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8568" } ], "weight": 0.0 }, { "disease_id": "DOID:9111", "name": "cutaneous leishmaniasis", "description": "A leishmaniasis that involves skin infection caused by Leishmania species, resulting in one or more cutaneous lesions.", "url": "https://disease-ontology.org/term/DOID:9111", "evidence": [ { "id": "9111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9111" } ], "weight": 0.0 }, { "disease_id": "DOID:9169", "name": "Wiskott-Aldrich syndrome", "description": "A syndrome that is characterized by abnormal immune system function and a reduced ability to form blood clots resulting from a decrease in the number and size of blood cell fragments involved in clotting (microthrombocytopenia).", "url": "https://disease-ontology.org/term/DOID:9169", "evidence": [ { "id": "9169", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9169" } ], "weight": 0.0 }, { "disease_id": "DOID:9206", "name": "Barrett's esophagus", "description": "An esophageal disease characterized by a change of normal esophageal squamous epithelium to a columnar and intestinal-type epithelium.", "url": "https://disease-ontology.org/term/DOID:9206", "evidence": [ { "id": "9206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9206" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:93", "name": "language disorder", "description": "A communication disorder that involves the processing of linguistic information.", "url": "https://disease-ontology.org/term/DOID:93", "evidence": [ { "id": "93", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:93" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 }, { "disease_id": "DOID:9955", "name": "hypoplastic left heart syndrome", "description": "A congenital heart disease characterized by abnormal development of the left-sided structures of the heart.", "url": "https://disease-ontology.org/term/DOID:9955", "evidence": [ { "id": "9955", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9955" } ], "weight": 0.0 } ], "biological_process": [ { "name": "operant conditioning", "id": "GO:0035106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035106", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "locomotion", "id": "GO:0040011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040011", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "male courtship behavior, veined wing generated song production", "id": "GO:0045433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045433", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6N2", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6N2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JE21-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1484, "chemical_mass": 162616.0, "gene_names": "mmd;CG15603;CG15604;CG42252;CG9163;CT26192;Dmel\\CG42252;Dmel_CG42252;mmd", "protein_name": "", "disease": [ { "disease_id": "DOID:0080434", "name": "developmental and epileptic encephalopathy 61", "description": "A developmental and epileptic encephalopathy that has_material_basis_in homozygous or compound heterozygous mutation in the ADAM22 gene on chromosome 7q21.", "url": "https://disease-ontology.org/term/DOID:0080434", "evidence": [ { "id": "0080434", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080434" } ], "weight": 0.0 } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "X2JE21", "url": "https://www.uniprot.org/uniprotkb/X2JE21" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JAM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 4526, "chemical_mass": 496785.0, "gene_names": "Svil;CG1141;CG12790;CG13797;CG13798;CG13799;CG13800;CG16763;CG16764;CG32306;CG33231;CG33232;CG42669;CG45186;Dmel\\CG45186;Dmel_CG45186;Svil;c62E-11", "protein_name": "", "disease": [ { "disease_id": "DOID:0112108", "name": "myofibrillar myopathy 10", "description": "A myofibrillar myopathy characterized by onset of muscle pain, cramping, and exercise fatigue in the first or second decades of life that has_material_basis_in homozygous or compound heterozygous mutation in the SVIL gene on chromosome 10p11.23.", "url": "https://disease-ontology.org/term/DOID:0112108", "evidence": [ { "id": "0112108", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112108" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" } ], "biological_process": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "actin filament capping", "id": "GO:0051693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051693", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "actin polymerization or depolymerization", "id": "GO:0008154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008154", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" }, { "name": "actin filament severing", "id": "GO:0051014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051014", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" } ], "cellular_component": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "X2JAM4", "url": "https://www.uniprot.org/uniprotkb/X2JAM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JAM4-1", "start_pos": "1450", "end_pos": "1450", "site_lbl": "Thr1450", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1450, "start_aa": "Thr", "end_pos": 1450, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1450", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAM4-1", "start_pos": "1993", "end_pos": "1993", "site_lbl": "Thr1993", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1993, "start_aa": "Thr", "end_pos": 1993, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1993", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAM4-1", "start_pos": "2804", "end_pos": "2804", "site_lbl": "Thr2804", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2804, "start_aa": "Thr", "end_pos": 2804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2804", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAM4-1", "start_pos": "494", "end_pos": "494", "site_lbl": "Thr494", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 494, "start_aa": "Thr", "end_pos": 494, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr494", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A023GPK8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1447, "chemical_mass": 158042.0, "gene_names": "fred;CG12675;CG31774;CG3390;CG3393;CT11413;Dmel\\CG31774;Dmel_CG31774;Fred;fred", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" } ], "biological_process": [ { "name": "sensory organ development", "id": "GO:0007423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007423", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "adult chitin-based cuticle pattern formation", "id": "GO:0035018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035018", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" }, { "name": "regulation of establishment of planar polarity", "id": "GO:0090175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090175", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A023GPK8", "url": "https://www.uniprot.org/uniprotkb/A0A023GPK8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A023GPK8-1", "start_pos": "1205", "end_pos": "1205", "site_lbl": "Thr1205", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1205, "start_aa": "Thr", "end_pos": 1205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1205", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A023GPK8-1", "start_pos": "135", "end_pos": "135", "site_lbl": "Thr135", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JNK4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 665, "chemical_mass": 74103.0, "gene_names": "Cip4;CG11341;CG15015;CIP4;Cip4;DCIP4;Dmel\\CG15015;Dmel_CG15015;cip4;dCIP4;dcip4", "protein_name": "", "disease": [ { "disease_id": "DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.", "url": "https://disease-ontology.org/term/DOID:12858", "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "GTPase activating protein binding", "id": "GO:0032794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032794", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" } ], "biological_process": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "negative regulation of actin nucleation", "id": "GO:0051126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051126", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "mesoderm development", "id": "GO:0007498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007498", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "plasma membrane tubulation", "id": "GO:0097320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097320", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "regulation of synaptic assembly at neuromuscular junction", "id": "GO:0008582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008582", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "germarium-derived female germ-line cyst encapsulation", "id": "GO:0030708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030708", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "regulation of adherens junction organization", "id": "GO:1903391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903391", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "cellularization", "id": "GO:0007349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007349", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "imaginal disc-derived wing hair organization", "id": "GO:0035317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035317", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" }, { "name": "negative regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045886", "evidence": [ { "database": "UniProtKB", "id": "A8JNK4", "url": "https://www.uniprot.org/uniprotkb/A8JNK4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JEY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 798, "chemical_mass": 91522.0, "gene_names": "AMPdeam;AMP deam;AMPdeam;CG11058;CG11065;CG15762;CG32626;Dmel\\CG32626;Dmel_CG32626", "protein_name": "AMP deaminase", "disease": [ { "disease_id": "DOID:0051064", "name": "left ventricular failure", "description": "A congestive heart failure that is characterized by dysfunction of the left ventricle, resulting insufficient delivery of blood to vital organs.", "url": "https://disease-ontology.org/term/DOID:0051064", "evidence": [ { "id": "0051064", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051064" } ], "weight": 0.0 }, { "disease_id": "DOID:0060264", "name": "pontocerebellar hypoplasia", "description": "A neurodegenerative disease that is characterized by underdevelopment of the pons and cerebellum.", "url": "https://disease-ontology.org/term/DOID:0060264", "evidence": [ { "id": "0060264", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060264" } ], "weight": 0.0 }, { "disease_id": "DOID:0060278", "name": "pontocerebellar hypoplasia type 9", "description": "A pontocerebellar hypoplasia that is characterized by progressive microcephaly, spasticity, seizure and brain atrophy, has_material_basis_in autosomal recessive inheritance of mutation in the AMPD2 gene.", "url": "https://disease-ontology.org/term/DOID:0060278", "evidence": [ { "id": "0060278", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060278" } ], "weight": 0.0 }, { "disease_id": "DOID:0110814", "name": "hereditary spastic paraplegia 63", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the AMPD2 gene on chromosome 1p13.", "url": "https://disease-ontology.org/term/DOID:0110814", "evidence": [ { "id": "0110814", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110814" } ], "weight": 0.0 }, { "disease_id": "DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.", "url": "https://disease-ontology.org/term/DOID:3393", "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ], "weight": 0.0 }, { "disease_id": "DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:3910", "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ], "weight": 0.0 }, { "disease_id": "DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.", "url": "https://disease-ontology.org/term/DOID:6000", "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" } ], "molecular_function": [ { "name": "AMP deaminase activity", "id": "GO:0003876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003876", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" } ], "biological_process": [ { "name": "IMP salvage", "id": "GO:0032264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032264", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" }, { "name": "AMP metabolic process", "id": "GO:0046033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046033", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" }, { "name": "IMP biosynthetic process", "id": "GO:0006188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006188", "evidence": [ { "database": "UniProtKB", "id": "X2JEY5", "url": "https://www.uniprot.org/uniprotkb/X2JEY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VZ41-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 532, "chemical_mass": 60690.0, "gene_names": "SmydA-4;CG11160;Dmel\\CG11160;Dmel_CG11160;SmydA-4", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" } ], "molecular_function": [ { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "N-methyltransferase activity", "id": "GO:0008170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008170", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "protein methyltransferase activity", "id": "GO:0008276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008276", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ41", "url": "https://www.uniprot.org/uniprotkb/Q9VZ41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9W4S3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4S3", "url": "https://www.uniprot.org/uniprotkb/Q9W4S3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 558, "chemical_mass": 66127.0, "gene_names": "Dmel\\CG10801;CG10801;Dmel\\CG10801;Dmel_CG10801", "protein_name": "BACK domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9W4G6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4G6", "url": "https://www.uniprot.org/uniprotkb/Q9W4G6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1893, "chemical_mass": 211120.0, "gene_names": "CG2861;Dmel\\CG2861;CG2861;Dmel\\CG2861;Dmel_CG2861", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W4G6-1", "start_pos": "595", "end_pos": "595", "site_lbl": "Thr595", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 595, "start_aa": "Thr", "end_pos": 595, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr595", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVM0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 630, "chemical_mass": 68916.0, "gene_names": "Dmel\\CG5535;anon-WO0118547.111;CG5535;Dmel\\CG5535;Dmel_CG5535;anon-WO0118547.111", "protein_name": "Cationic amino acid transporter C-terminal domain-containing protein", "disease": [ { "disease_id": "DOID:0111666", "name": "proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome", "description": "A syndrome characterized by hydranencephaly, glomeruloid vasculopathy of the central nervous system and retinal vessels, diffuse clastic ischemic lesions of the brain stem, basal ganglia, and spinal cord with calcifications, and fetal akinesia with arthrogryposis that has_material_basis_in homozygous or compound heterozygous mutation in the FLVCR2 gene on chromosome 14q24.3.", "url": "https://disease-ontology.org/term/DOID:0111666", "evidence": [ { "id": "0111666", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111666" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" } ], "molecular_function": [ { "name": "amino acid transmembrane transporter activity", "id": "GO:0015171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015171", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-ornithine transmembrane transporter activity", "id": "GO:0000064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000064", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-lysine transmembrane transporter activity", "id": "GO:0015189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015189", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-arginine transmembrane transporter activity", "id": "GO:0061459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" } ], "biological_process": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-arginine import across plasma membrane", "id": "GO:0097638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097638", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" }, { "name": "L-ornithine transmembrane transport", "id": "GO:1903352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903352", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM0", "url": "https://www.uniprot.org/uniprotkb/Q9VVM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVM0-1", "start_pos": "112", "end_pos": "112", "site_lbl": "Thr112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VR26-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 456, "chemical_mass": 54834.0, "gene_names": "Dmel\\CG3294;CG3294;Dmel\\CG3294;Dmel_CG3294;cg3294", "protein_name": "", "disease": [ { "disease_id": "DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets.", "url": "https://disease-ontology.org/term/DOID:0050908", "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ], "weight": 0.0 }, { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "pre-mRNA 3'-splice site binding", "id": "GO:0030628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030628", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" } ], "cellular_component": [ { "name": "U2AF complex", "id": "GO:0089701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0089701", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "Q9VR26", "url": "https://www.uniprot.org/uniprotkb/Q9VR26" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JFW7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JFW7", "url": "https://www.uniprot.org/uniprotkb/X2JFW7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 134, "chemical_mass": 14399.0, "gene_names": "Dmel\\CG34331;CG34331;Dmel\\CG34331;Dmel_CG34331", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9W4I6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4I6", "url": "https://www.uniprot.org/uniprotkb/Q9W4I6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 583, "chemical_mass": 62897.0, "gene_names": "Dmel\\CG3081;CG3081;Dmel\\CG3081;Dmel_CG3081;EG:84H4.4", "protein_name": "DUF4812 domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2803, "chemical_mass": 302857.0, "gene_names": "Nuak;CG11870;CG11871;CG11872;CG43143;Dmel\\CG43143;Dmel_CG43143;EMK/KIAA0537;KIAA0537;NUAK;Nuak1;Nuak;Omphk1", "protein_name": "", "disease": [ { "disease_id": "DOID:0060668", "name": "anencephaly", "description": "A congenital nervous system abnormality characterized by failure of the anterior neuropore to close resulting in partial or complete absence of the cranial vault accompanied by absence of overlying tissues, including the brain and cerebral hemispheres, skull and scalp.", "url": "https://disease-ontology.org/term/DOID:0060668", "evidence": [ { "id": "0060668", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060668" } ], "weight": 0.0 }, { "disease_id": "DOID:13223", "name": "uterine fibroid", "description": "An uterine benign neoplasm derived from the smooth muscle layer of the uterus.", "url": "https://disease-ontology.org/term/DOID:13223", "evidence": [ { "id": "13223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13223" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A6H2EG35", "url": "https://www.uniprot.org/uniprotkb/A0A6H2EG35" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "1039", "end_pos": "1039", "site_lbl": "Thr1039", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1039, "start_aa": "Thr", "end_pos": 1039, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1039", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "1046", "end_pos": "1046", "site_lbl": "Thr1046", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1046, "start_aa": "Thr", "end_pos": 1046, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1046", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A6H2EG35", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A6H2EG35" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "1047", "end_pos": "1047", "site_lbl": "Ser1047", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1047, "start_aa": "Ser", "end_pos": 1047, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1047", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A6H2EG35", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A6H2EG35" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "2072", "end_pos": "2072", "site_lbl": "Thr2072", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2072, "start_aa": "Thr", "end_pos": 2072, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2072", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "2074", "end_pos": "2074", "site_lbl": "Thr2074", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2074, "start_aa": "Thr", "end_pos": 2074, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2074", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "2519", "end_pos": "2519", "site_lbl": "Thr2519", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2519, "start_aa": "Thr", "end_pos": 2519, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2519", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "531", "end_pos": "531", "site_lbl": "Thr531", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "669", "end_pos": "669", "site_lbl": "Thr669", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 669, "start_aa": "Thr", "end_pos": 669, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr669", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A6H2EG35-1", "start_pos": "713", "end_pos": "713", "site_lbl": "Ser713", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 713, "start_aa": "Ser", "end_pos": 713, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser713", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A6H2EG35", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A6H2EG35" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1Z9K9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z9K9", "url": "https://www.uniprot.org/uniprotkb/A1Z9K9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 160, "chemical_mass": 18633.0, "gene_names": "CG13353;Dmel\\CG42288;CG13353;CG42288;Dmel\\CG42288;Dmel_CG42288", "protein_name": "", "disease": [], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1Z9K9", "url": "https://www.uniprot.org/uniprotkb/A1Z9K9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4KHG9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHG9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHG9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 819, "chemical_mass": 92010.0, "gene_names": "Dmel\\CG13643;CG13642;CG13643;Dmel\\CG13643;Dmel_CG13643", "protein_name": "Chitin-binding type-2 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHG9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHG9" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHG9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHG9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KHG9-1", "start_pos": "312", "end_pos": "312", "site_lbl": "Thr312", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 312, "start_aa": "Thr", "end_pos": 312, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr312", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1ZBC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1471, "chemical_mass": 158176.0, "gene_names": "Sik3;CG15072;CG18604;CG42856;Dmel\\CG42856;Dmel_CG42856;EMK/KIAA0999;KIAA0999;SIK3;SIK;Sik3", "protein_name": "non-specific serine/threonine protein kinase", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" } ], "biological_process": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "negative regulation of triglyceride catabolic process", "id": "GO:0010897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010897", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "circadian sleep/wake cycle, sleep", "id": "GO:0050802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050802", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" }, { "name": "positive regulation of pentose-phosphate shunt", "id": "GO:1905857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905857", "evidence": [ { "database": "UniProtKB", "id": "A1ZBC4", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBC4-1", "start_pos": "1127", "end_pos": "1127", "site_lbl": "Thr1127", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1127, "start_aa": "Thr", "end_pos": 1127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1127", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9W233-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W233", "url": "https://www.uniprot.org/uniprotkb/Q9W233" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 813, "chemical_mass": 89190.0, "gene_names": "Idit;33143;CG13509;CG33143;CG4232;Dmel\\CG33143;Dmel_CG33143;mdcds_16487", "protein_name": "Fibronectin type-III domain-containing protein", "disease": [], "biological_process": [ { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "Q9W233", "url": "https://www.uniprot.org/uniprotkb/Q9W233" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1Z782-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 646, "chemical_mass": 71722.0, "gene_names": "Dmel\\CG8726;CG8726;Dmel\\CG8726;Dmel_CG8726", "protein_name": "PX domain-containing protein kinase-like protein", "disease": [ { "disease_id": "DOID:2835", "name": "polycythemia due to hypoxia", "description": "", "url": "https://disease-ontology.org/term/DOID:2835", "evidence": [ { "id": "2835", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2835" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" } ], "biological_process": [ { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A1Z782", "url": "https://www.uniprot.org/uniprotkb/A1Z782" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1Z830-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 485, "chemical_mass": 53881.0, "gene_names": "ptch;CG12128;Dmel\\CG12128;Dmel_CG12128", "protein_name": "28S rRNA (uridine-N(3))-methyltransferase", "disease": [], "cellular_component": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" } ], "molecular_function": [ { "name": "rRNA (uridine-N3-)-methyltransferase activity", "id": "GO:0070042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070042", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" }, { "name": "S-adenosyl-L-methionine binding", "id": "GO:1904047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904047", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA base methylation", "id": "GO:0070475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070475", "evidence": [ { "database": "UniProtKB", "id": "A1Z830", "url": "https://www.uniprot.org/uniprotkb/A1Z830" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1Z8F4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2577, "chemical_mass": 276829.0, "gene_names": "shn;BEST:SD06302;CG7734;Dmel\\CG7734;EP(2)2359;EP2359;SD06302;SHN;Schnurri;Shn;l(2)04738;quo;shn", "protein_name": "Protein schnurri", "disease": [ { "disease_id": "DOID:0050787", "name": "juvenile polyposis syndrome", "description": "A gastrointestinal system disease that is characterized by predisposition to hamartomatous benign polyps in the gastrointestinal tract, specifically in the stomach, small intestine, colon, and rectum.", "url": "https://disease-ontology.org/term/DOID:0050787", "evidence": [ { "id": "0050787", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050787" } ], "weight": 0.0 }, { "disease_id": "DOID:0070073", "name": "autosomal dominant intellectual developmental disorder 43", "description": "An autosomal dominant intellectual developmental disorder characterized by delayed psychomotor development with impaired intellectual development and poor speech, hypotonia, and nonspecific dysmorphic features that has_material_basis_in an autosomal dominant mutation of the HIVEP2 gene on chromosome 6q24.2.", "url": "https://disease-ontology.org/term/DOID:0070073", "evidence": [ { "id": "0070073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070073" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.", "url": "https://disease-ontology.org/term/DOID:5419", "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "midgut development", "id": "GO:0007494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007494", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "ectoderm development", "id": "GO:0007398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007398", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "Malpighian tubule morphogenesis", "id": "GO:0007443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007443", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "negative regulation of salivary gland boundary specification", "id": "GO:0045705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045705", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "wing disc dorsal/ventral pattern formation", "id": "GO:0048190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048190", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "1060", "end_pos": "1060", "site_lbl": "Thr1060", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1060, "start_aa": "Thr", "end_pos": 1060, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1060", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "1062", "end_pos": "1062", "site_lbl": "Thr1062", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1062, "start_aa": "Thr", "end_pos": 1062, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1062", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "1514", "end_pos": "1514", "site_lbl": "Thr1514", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1514, "start_aa": "Thr", "end_pos": 1514, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1514", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "823", "end_pos": "823", "site_lbl": "Thr823", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 823, "start_aa": "Thr", "end_pos": 823, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr823", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A1Z8F4-1", "start_pos": "517", "end_pos": "517", "site_lbl": "Cys517", "weight": 0.0, "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Results in ectopic venation of developing wings; when associated with 486-S--S-489. Phenotype is more severe when also associated with 1834-N--N-1838 and 1846-S--S-1849.", "evidence": [ { "database": "UniProtKB", "id": "A1Z8F4", "url": "https://www.uniprot.org/uniprotkb/A1Z8F4" }, { "database": "PubMed", "id": "38344065", "url": "https://glygen.org/publication/PubMed/38344065" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9W2Z7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2Z7", "url": "https://www.uniprot.org/uniprotkb/Q9W2Z7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 364, "chemical_mass": 38031.0, "gene_names": "CG12634;CG12649;CG18512;Dmel\\CG32694;BcDNA:RE02049;CG12634;CG12649;CG18512;CG32694;Dmel\\CG32694;Dmel_CG32694", "protein_name": "Cell wall protein DAN4", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W2Z7-1", "start_pos": "126", "end_pos": "126", "site_lbl": "Thr126", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 126, "start_aa": "Thr", "end_pos": 126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr126", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VRW2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1320, "chemical_mass": 146536.0, "gene_names": "AMT;Dmel\\CG10226;AMT;CG10226;DmCG10226;Dmel\\CG10226;Dmel_CG10226", "protein_name": "Multidrug resistance protein homolog 65", "disease": [ { "disease_id": "DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep.", "url": "https://disease-ontology.org/term/DOID:0050848", "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ], "weight": 0.0 }, { "disease_id": "DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin.", "url": "https://disease-ontology.org/term/DOID:0050861", "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ], "weight": 0.0 }, { "disease_id": "DOID:0060643", "name": "primary sclerosing cholangitis", "description": "A sclerosing cholangitis characterized by fibroobliterative inflammation of the biliary tract, leading to cirrhosis and portal hypertension.", "url": "https://disease-ontology.org/term/DOID:0060643", "evidence": [ { "id": "0060643", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060643" } ], "weight": 0.0 }, { "disease_id": "DOID:0060750", "name": "familial temporal lobe epilepsy 3", "description": "A temporal lobe epilepsy characterized by simple or complex partial seizures often accompanied by intense feelings of deja or altered awareness and that has_material_basis_in variation in the chromosome region 4q13.2-q21.3.", "url": "https://disease-ontology.org/term/DOID:0060750", "evidence": [ { "id": "0060750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060750" } ], "weight": 0.0 }, { "disease_id": "DOID:0070223", "name": "progressive familial intrahepatic cholestasis 3", "description": "A progressive familial intrahepatic cholestasis characterized by autosomal recessive inheritance of intrahepatic cholestasis and elevated serum GGT1 activity that has_material_basis_in mutation in the ABCB4 gene on chromosome 7q21.12.", "url": "https://disease-ontology.org/term/DOID:0070223", "evidence": [ { "id": "0070223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070223" } ], "weight": 0.0 }, { "disease_id": "DOID:0070229", "name": "intrahepatic cholestasis of pregnancy 3", "description": "An intrahepatic cholestasis of pregnancy characterized by autosomal dominant inheritance that has_material_basis_in mutation in the ABCB4 gene on chromosome 7q21.", "url": "https://disease-ontology.org/term/DOID:0070229", "evidence": [ { "id": "0070229", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070229" } ], "weight": 0.0 }, { "disease_id": "DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.", "url": "https://disease-ontology.org/term/DOID:0080208", "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ], "weight": 0.0 }, { "disease_id": "DOID:0080797", "name": "nasal type extranodal NK/T-cell lymphoma", "description": "A mature T-cell and NK-cell lymphoma that is characterized by an often angiocentric and angiodestructive cellular infiltrate composed of EBV positive NK/T cells.", "url": "https://disease-ontology.org/term/DOID:0080797", "evidence": [ { "id": "0080797", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080797" } ], "weight": 0.0 }, { "disease_id": "DOID:0110893", "name": "inflammatory bowel disease 13", "description": "An inflammatory bowel disease that has_material_basis_in variation in the ABCB1 gene on chromosome 7q21.1.", "url": "https://disease-ontology.org/term/DOID:0110893", "evidence": [ { "id": "0110893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110893" } ], "weight": 0.0 }, { "disease_id": "DOID:10159", "name": "osteonecrosis", "description": "An ischemic bone disease that results_in necrosis located_in bone.", "url": "https://disease-ontology.org/term/DOID:10159", "evidence": [ { "id": "10159", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10159" } ], "weight": 0.0 }, { "disease_id": "DOID:10939", "name": "antisocial personality disorder", "description": "A personality disorder that involves a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood.", "url": "https://disease-ontology.org/term/DOID:10939", "evidence": [ { "id": "10939", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10939" } ], "weight": 0.0 }, { "disease_id": "DOID:1168", "name": "familial hyperlipidemia", "description": "A lipid metabolism disease that is characterized by elevated levels of lipids in the blood.", "url": "https://disease-ontology.org/term/DOID:1168", "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ], "weight": 0.0 }, { "disease_id": "DOID:12236", "name": "primary biliary cholangitis", "description": "A liver cirrhosis characterized by chronic and slow progressive destruction of intrahepatic bile ducts.", "url": "https://disease-ontology.org/term/DOID:12236", "evidence": [ { "id": "12236", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12236" } ], "weight": 0.0 }, { "disease_id": "DOID:12365", "name": "malaria", "description": "A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.", "url": "https://disease-ontology.org/term/DOID:12365", "evidence": [ { "id": "12365", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12365" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:13413", "name": "hepatic encephalopathy", "description": "A brain disease that is characterized by loss of brain function, the occurrence of confusion, altered level of consciousness, and coma that results when the liver is unable to remove toxins from the blood.", "url": "https://disease-ontology.org/term/DOID:13413", "evidence": [ { "id": "13413", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13413" } ], "weight": 0.0 }, { "disease_id": "DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum.", "url": "https://disease-ontology.org/term/DOID:13580", "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ], "weight": 0.0 }, { "disease_id": "DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs.", "url": "https://disease-ontology.org/term/DOID:1485", "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ], "weight": 0.0 }, { "disease_id": "DOID:1824", "name": "status epilepticus", "description": "", "url": "https://disease-ontology.org/term/DOID:1824", "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ], "weight": 0.0 }, { "disease_id": "DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.", "url": "https://disease-ontology.org/term/DOID:1826", "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ], "weight": 0.0 }, { "disease_id": "DOID:1849", "name": "cannabis dependence", "description": "A drug dependence that involves the continued use of cannabis despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:1849", "evidence": [ { "id": "1849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1849" } ], "weight": 0.0 }, { "disease_id": "DOID:1852", "name": "intrahepatic cholestasis", "description": "A cholestasis characterized by impairment of the bile flow caused by obstruction located_in liver.", "url": "https://disease-ontology.org/term/DOID:1852", "evidence": [ { "id": "1852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1852" } ], "weight": 0.0 }, { "disease_id": "DOID:1949", "name": "cholecystitis", "description": "A cholangitis that is characterized by an inflammation that is located in the gallbladder.", "url": "https://disease-ontology.org/term/DOID:1949", "evidence": [ { "id": "1949", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1949" } ], "weight": 0.0 }, { "disease_id": "DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children.", "url": "https://disease-ontology.org/term/DOID:2154", "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ], "weight": 0.0 }, { "disease_id": "DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand.", "url": "https://disease-ontology.org/term/DOID:2316", "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:2559", "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:2917", "name": "cryoglobulinemia", "description": "A hypersensitivity reaction type IV disease that involves large amounts of cryoglobulins in the blood which become thick or gel-like in cold temperatures.", "url": "https://disease-ontology.org/term/DOID:2917", "evidence": [ { "id": "2917", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2917" } ], "weight": 0.0 }, { "disease_id": "DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis.", "url": "https://disease-ontology.org/term/DOID:2957", "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ], "weight": 0.0 }, { "disease_id": "DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin.", "url": "https://disease-ontology.org/term/DOID:2987", "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ], "weight": 0.0 }, { "disease_id": "DOID:3008", "name": "invasive ductal carcinoma", "description": "A breast ductal carcinoma that is characterized by infiltration into the fibrous or fatty tissue of the breast outside of the duct where it originated.", "url": "https://disease-ontology.org/term/DOID:3008", "evidence": [ { "id": "3008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3008" } ], "weight": 0.0 }, { "disease_id": "DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine.", "url": "https://disease-ontology.org/term/DOID:3070", "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ], "weight": 0.0 }, { "disease_id": "DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.", "url": "https://disease-ontology.org/term/DOID:3328", "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ], "weight": 0.0 }, { "disease_id": "DOID:3602", "name": "toxic encephalopathy", "description": "A nervous system disease that results from exposure to neurotoxicants and is characterized by an altered mental status, memory loss, and visual problems.", "url": "https://disease-ontology.org/term/DOID:3602", "evidence": [ { "id": "3602", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3602" } ], "weight": 0.0 }, { "disease_id": "DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.", "url": "https://disease-ontology.org/term/DOID:3908", "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ], "weight": 0.0 }, { "disease_id": "DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney.", "url": "https://disease-ontology.org/term/DOID:4450", "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ], "weight": 0.0 }, { "disease_id": "DOID:4481", "name": "allergic rhinitis", "description": "A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites.", "url": "https://disease-ontology.org/term/DOID:4481", "evidence": [ { "id": "4481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4481" } ], "weight": 0.0 }, { "disease_id": "DOID:5082", "name": "liver cirrhosis", "description": "", "url": "https://disease-ontology.org/term/DOID:5082", "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ], "weight": 0.0 }, { "disease_id": "DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.", "url": "https://disease-ontology.org/term/DOID:526", "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ], "weight": 0.0 }, { "disease_id": "DOID:635", "name": "acquired immunodeficiency syndrome", "description": "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.", "url": "https://disease-ontology.org/term/DOID:635", "evidence": [ { "id": "635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:635" } ], "weight": 0.0 }, { "disease_id": "DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.", "url": "https://disease-ontology.org/term/DOID:684", "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores.", "url": "https://disease-ontology.org/term/DOID:8577", "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ], "weight": 0.0 }, { "disease_id": "DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine.", "url": "https://disease-ontology.org/term/DOID:8778", "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 }, { "disease_id": "DOID:9974", "name": "drug dependence", "description": "A substance dependence that involves the continued use of drugs despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9974", "evidence": [ { "id": "9974", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9974" } ], "weight": 0.0 }, { "disease_id": "DOID:9976", "name": "heroin dependence", "description": "An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.", "url": "https://disease-ontology.org/term/DOID:9976", "evidence": [ { "id": "9976", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9976" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "efflux transmembrane transporter activity", "id": "GO:0015562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015562", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "ATP-binding cassette (ABC) transporter complex", "id": "GO:0043190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043190", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" } ], "biological_process": [ { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "renal tubular secretion", "id": "GO:0097254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097254", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" }, { "name": "xenobiotic transport", "id": "GO:0042908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042908", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW2", "url": "https://www.uniprot.org/uniprotkb/Q9VRW2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRW2-1", "start_pos": "19", "end_pos": "19", "site_lbl": "Thr19", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JE74-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1170, "chemical_mass": 127040.0, "gene_names": "X11L;CG5675;CG5678;Dmel\\CG5675;Dmel_CG5675;Dmint1;Dmint;MINT;Mint;X11-like;X11/Mint;X11Lalpha;X11L;X11;dX11/Mint;dX11Lalpha;dX11L;dX11;x11/Mint;x11Lalpha", "protein_name": "", "disease": [], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" } ], "molecular_function": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "X2JE74", "url": "https://www.uniprot.org/uniprotkb/X2JE74" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JE74-1", "start_pos": "58", "end_pos": "58", "site_lbl": "Thr58", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JE74-1", "start_pos": "896", "end_pos": "896", "site_lbl": "Thr896", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 896, "start_aa": "Thr", "end_pos": 896, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr896", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VW79-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW79", "url": "https://www.uniprot.org/uniprotkb/Q9VW79" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 126, "chemical_mass": 13832.0, "gene_names": "Dmel\\CG14187;CG14187;Dmel\\CG14187;Dmel_CG14187", "protein_name": "", "disease": [], "biological_process": [ { "name": "chorion-containing eggshell formation", "id": "GO:0007304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007304", "evidence": [ { "database": "UniProtKB", "id": "Q9VW79", "url": "https://www.uniprot.org/uniprotkb/Q9VW79" } ], "pmid": "" } ], "cellular_component": [ { "name": "egg chorion", "id": "GO:0042600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042600", "evidence": [ { "database": "UniProtKB", "id": "Q9VW79", "url": "https://www.uniprot.org/uniprotkb/Q9VW79" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4KI34-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 941, "chemical_mass": 98521.0, "gene_names": "cindr;BcDNA:GH03163;CD2AP;CG11316;CG1408;CG31012;Cindir;Cindr;Dmel\\CG31012;Dmel_CG31012;cindr", "protein_name": "", "disease": [ { "disease_id": "DOID:0111999", "name": "immunodeficiency 61", "description": "A B cell deficiency characterized by onset in early childhood of recurrent infections due to an intrinsic defect in the ability of B cells to produce antibodies that has_material_basis_in hemizygous mutation in the SH3KBP1 gene on chromosome Xp22.12.", "url": "https://disease-ontology.org/term/DOID:0111999", "evidence": [ { "id": "0111999", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111999" } ], "weight": 0.0 }, { "disease_id": "DOID:0112245", "name": "focal segmental glomerulosclerosis 3", "description": "A focal segmental glomerulosclerosis that has_material_basis_in loss of function mutation in the CD2AP gene on chromosome 6p12.3.", "url": "https://disease-ontology.org/term/DOID:0112245", "evidence": [ { "id": "0112245", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112245" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "", "url": "https://disease-ontology.org/term/DOID:1312", "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ], "weight": 0.0 }, { "disease_id": "DOID:680", "name": "tauopathy", "description": "A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain.", "url": "https://disease-ontology.org/term/DOID:680", "evidence": [ { "id": "680", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:680" } ], "weight": 0.0 }, { "disease_id": "DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease.", "url": "https://disease-ontology.org/term/DOID:783", "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ], "weight": 0.0 } ], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "intercellular bridge organization", "id": "GO:0043063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043063", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "positive regulation of receptor-mediated endocytosis", "id": "GO:0048260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048260", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "adherens junction assembly", "id": "GO:0034333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034333", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "compound eye morphogenesis", "id": "GO:0001745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001745", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" } ], "molecular_function": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "GTPase activating protein binding", "id": "GO:0032794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032794", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" } ], "cellular_component": [ { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" }, { "name": "apical cortex", "id": "GO:0045179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045179", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KI34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JQY2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JQY2", "url": "https://www.uniprot.org/uniprotkb/A8JQY2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 581, "chemical_mass": 63256.0, "gene_names": "Dmel\\CG12213;anon-87Ab;3;87A7-9/3;CG12213;Dmel\\CG12213;Dmel_CG12213;anon-87Ab", "protein_name": "Golgi integral membrane protein 4", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4K6X8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K6X8", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K6X8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 34463.0, "gene_names": "Dmel\\CG11693;CG11693;Dmel\\CG11693;Dmel_CG11693", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4KF34-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 835, "chemical_mass": 94174.0, "gene_names": "CG12167;CG12167;CG12168;CG31550;Dmel\\CG31550;Dmel_CG31550", "protein_name": "G-patch domain-containing protein", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KF34", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KF34" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4KF34-1", "start_pos": "392", "end_pos": "392", "site_lbl": "Thr392", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 392, "start_aa": "Thr", "end_pos": 392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr392", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JF48-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JF48", "url": "https://www.uniprot.org/uniprotkb/X2JF48" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 923, "chemical_mass": 105076.0, "gene_names": "Dmel\\CG6324;CG6324;Dmel\\CG6324;Dmel_CG6324", "protein_name": "", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "X2JF48", "url": "https://www.uniprot.org/uniprotkb/X2JF48" } ], "pmid": "" } ], "biological_process": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "X2JF48", "url": "https://www.uniprot.org/uniprotkb/X2JF48" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VWP5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2486, "chemical_mass": 259465.0, "gene_names": "htk;ARID4B;CG34422;CG7274;CG7282;Dmel\\CG34422;Dmel_CG34422;Htk;Q9VWP3_DROME;htk", "protein_name": "", "disease": [ { "disease_id": "DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.", "url": "https://disease-ontology.org/term/DOID:9119", "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" } ], "molecular_function": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "transcription coregulator binding", "id": "GO:0001221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001221", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP5", "url": "https://www.uniprot.org/uniprotkb/Q9VWP5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1310", "end_pos": "1310", "site_lbl": "Thr1310", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1310, "start_aa": "Thr", "end_pos": 1310, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1310", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1407", "end_pos": "1407", "site_lbl": "Thr1407", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1407, "start_aa": "Thr", "end_pos": 1407, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1407", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1608", "end_pos": "1608", "site_lbl": "Thr1608", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1608, "start_aa": "Thr", "end_pos": 1608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1608", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1620", "end_pos": "1620", "site_lbl": "Thr1620", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1620, "start_aa": "Thr", "end_pos": 1620, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1620", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "1953", "end_pos": "1953", "site_lbl": "Thr1953", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1953, "start_aa": "Thr", "end_pos": 1953, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1953", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "2112", "end_pos": "2112", "site_lbl": "Thr2112", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2112, "start_aa": "Thr", "end_pos": 2112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2112", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "456", "end_pos": "456", "site_lbl": "Thr456", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VWP5-1", "start_pos": "844", "end_pos": "844", "site_lbl": "Thr844", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 844, "start_aa": "Thr", "end_pos": 844, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr844", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VYL1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 572, "chemical_mass": 64317.0, "gene_names": "Fpgs1;CG2543;Dmel\\CG2543;Dmel_CG2543;Fpgs1;Fpgs", "protein_name": "Folylpolyglutamate synthase", "disease": [], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "tetrahydrofolylpolyglutamate synthase activity", "id": "GO:0004326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004326", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" } ], "biological_process": [ { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" }, { "name": "tetrahydrofolylpolyglutamate biosynthetic process", "id": "GO:0046901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046901", "evidence": [ { "database": "UniProtKB", "id": "Q9VYL1", "url": "https://www.uniprot.org/uniprotkb/Q9VYL1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9W398-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W398", "url": "https://www.uniprot.org/uniprotkb/Q9W398" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 146, "chemical_mass": 16119.0, "gene_names": "CG15366;CG7267;CG15366;CG44325;CG7267;Dmel\\CG44325;Dmel_CG44325", "protein_name": "", "disease": [], "biological_process": [ { "name": "septate junction assembly", "id": "GO:0019991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019991", "evidence": [ { "database": "UniProtKB", "id": "Q9W398", "url": "https://www.uniprot.org/uniprotkb/Q9W398" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W398", "url": "https://www.uniprot.org/uniprotkb/Q9W398" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8DZ29-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1919, "chemical_mass": 211123.0, "gene_names": "eIF4G1;CG10811;Dmel\\CG10811;Dmel_CG10811;EIF4G1;EIF4G;Eif4G;deIF4G;eIF-4G;eIF4G1;eIF4G;eIF4g;eiF-4G;p200", "protein_name": "", "disease": [ { "disease_id": "DOID:0060892", "name": "late onset Parkinson's disease", "description": "A Parkinson's disease characterized by onset of motor symptoms typically after 60 years of age.", "url": "https://disease-ontology.org/term/DOID:0060892", "evidence": [ { "id": "0060892", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060892" } ], "weight": 0.0 }, { "disease_id": "DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.", "url": "https://disease-ontology.org/term/DOID:14330", "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "eukaryotic initiation factor 4E binding", "id": "GO:0008190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008190", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "A8DZ29", "url": "https://www.uniprot.org/uniprotkb/A8DZ29" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "1412", "end_pos": "1412", "site_lbl": "Thr1412", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1412, "start_aa": "Thr", "end_pos": 1412, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1412", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "1414", "end_pos": "1414", "site_lbl": "Thr1414", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1414, "start_aa": "Thr", "end_pos": 1414, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1414", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "539", "end_pos": "539", "site_lbl": "Ser539", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 539, "start_aa": "Ser", "end_pos": 539, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser539", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DZ29", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DZ29" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "562", "end_pos": "562", "site_lbl": "Ser562", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 562, "start_aa": "Ser", "end_pos": 562, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser562", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DZ29", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DZ29" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "564", "end_pos": "564", "site_lbl": "Thr564", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 564, "start_aa": "Thr", "end_pos": 564, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr564", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DZ29", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DZ29" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Thr569", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 569, "start_aa": "Thr", "end_pos": 569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr569", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "586", "end_pos": "586", "site_lbl": "Thr586", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 586, "start_aa": "Thr", "end_pos": 586, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr586", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "624", "end_pos": "624", "site_lbl": "Ser624", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 624, "start_aa": "Ser", "end_pos": 624, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser624", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A8DZ29", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A8DZ29" } ] } ] }, { "uniprot_canonical_ac": "A8DZ29-1", "start_pos": "715", "end_pos": "715", "site_lbl": "Thr715", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 715, "start_aa": "Thr", "end_pos": 715, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr715", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A6F7R657-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 709, "chemical_mass": 79477.0, "gene_names": "wdb;0318/07;07;B56-2;BEST:LD02456;BcDNA:LD34343;CG5643;Dmel\\CG5643;Dmel_CG5643;EP3559;LD02456;PP2-AB;PP2A-B';PP2A[B'-2];PP2A;PP2a;WDB;Wdb;Widerborst;dB56-2;dPP2A-B56-2;dPP2A;l(3)S031807;wbd;wdb", "protein_name": "", "disease": [ { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death.", "url": "https://disease-ontology.org/term/DOID:224", "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ], "weight": 0.0 } ], "biological_process": [ { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of lipid storage", "id": "GO:0010888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010888", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "meiotic spindle assembly", "id": "GO:0090306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090306", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "maintenance of sister chromatid cohesion", "id": "GO:0034086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034086", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" }, { "name": "protein phosphatase activator activity", "id": "GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "A0A6F7R657", "url": "https://www.uniprot.org/uniprotkb/A0A6F7R657" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2238, "chemical_mass": 255301.0, "gene_names": "brp;BRP;Brp;Bruchpilot;CG12932;CG12933;CG1931;CG30336;CG30337;CG34146;CG42344;Cast;Dmel\\CG42344;Dmel_CG42344;MAbnc82;Mabnc82;NC82;Nc82;brp;mAb nc82;mAbnc82;nc-82;nc82", "protein_name": "Protein bruchpilot", "disease": [], "biological_process": [ { "name": "cytoskeletal matrix organization at active zone", "id": "GO:0048789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048789", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synaptic vesicle clustering", "id": "GO:0097091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097091", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "maintenance of presynaptic active zone structure", "id": "GO:0048790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048790", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "presynaptic active zone organization", "id": "GO:1990709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990709", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "adult locomotory behavior", "id": "GO:0008344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "short-term memory", "id": "GO:0007614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007614", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "neurotransmitter secretion", "id": "GO:0007269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007269", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031630", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "presynaptic active zone assembly", "id": "GO:1904071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904071", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synapse maturation", "id": "GO:0060074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060074", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "anesthesia-resistant memory", "id": "GO:0007615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007615", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synaptic vesicle tethering involved in synaptic vesicle exocytosis", "id": "GO:0099069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099069", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "regulation of calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0150037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150037", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" } ], "cellular_component": [ { "name": "presynaptic active zone cytoplasmic component", "id": "GO:0098831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098831", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "cytoskeleton of presynaptic active zone", "id": "GO:0048788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048788", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "T-bar", "id": "GO:0098986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098986", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" }, { "name": "synaptic vesicle, readily releasable pool", "id": "GO:1990474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990474", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" } ], "molecular_function": [ { "name": "structural constituent of presynaptic active zone", "id": "GO:0098882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098882", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "151", "end_pos": "151", "site_lbl": "Thr151", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1677", "end_pos": "1677", "site_lbl": "Thr1677", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1677, "start_aa": "Thr", "end_pos": 1677, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1677", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K7K9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "569", "end_pos": "569", "site_lbl": "Thr569", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 569, "start_aa": "Thr", "end_pos": 569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr569", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0A0B4K7K9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1028", "end_pos": "1028", "site_lbl": "Ser1028", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1080", "end_pos": "1080", "site_lbl": "Thr1080", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1081", "end_pos": "1081", "site_lbl": "Ser1081", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "114", "end_pos": "114", "site_lbl": "Ser114", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "118", "end_pos": "118", "site_lbl": "Ser118", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Tyr130", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Ser133", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "137", "end_pos": "137", "site_lbl": "Ser137", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "139", "end_pos": "139", "site_lbl": "Ser139", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1666", "end_pos": "1666", "site_lbl": "Ser1666", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1668", "end_pos": "1668", "site_lbl": "Ser1668", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1679", "end_pos": "1679", "site_lbl": "Ser1679", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1681", "end_pos": "1681", "site_lbl": "Ser1681", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "16", "end_pos": "16", "site_lbl": "Ser16", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "1854", "end_pos": "1854", "site_lbl": "Ser1854", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "187", "end_pos": "187", "site_lbl": "Ser187", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "188", "end_pos": "188", "site_lbl": "Ser188", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "197", "end_pos": "197", "site_lbl": "Ser197", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "32", "end_pos": "32", "site_lbl": "Ser32", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "34", "end_pos": "34", "site_lbl": "Ser34", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "43", "end_pos": "43", "site_lbl": "Ser43", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "59", "end_pos": "59", "site_lbl": "Thr59", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "60", "end_pos": "60", "site_lbl": "Ser60", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "71", "end_pos": "71", "site_lbl": "Ser71", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Ser73", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "90", "end_pos": "90", "site_lbl": "Ser90", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Reduced hatching rate and disturbed axonal transport of active zone proteins; when associated with 71-A--A-73.", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "924", "end_pos": "924", "site_lbl": "Ser924", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "925", "end_pos": "925", "site_lbl": "Ser925", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4K7K9-1", "start_pos": "926", "end_pos": "926", "site_lbl": "Ser926", "weight": 0.0, "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4K7K9", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7K9" }, { "database": "PubMed", "id": "30745339", "url": "https://glygen.org/publication/PubMed/30745339" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1ZBJ6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1379, "chemical_mass": 147988.0, "gene_names": "Rgk1;CG30127;CG44011;CG9811;CT27512;Dmel\\CG44011;Dmel_CG44011;RGK1;Rgk1;rgk1", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" } ], "biological_process": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "anesthesia-resistant memory", "id": "GO:0007615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007615", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" }, { "name": "medium-term memory", "id": "GO:0072375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072375", "evidence": [ { "database": "UniProtKB", "id": "A1ZBJ6", "url": "https://www.uniprot.org/uniprotkb/A1ZBJ6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A1ZBJ6-1", "start_pos": "838", "end_pos": "838", "site_lbl": "Thr838", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 838, "start_aa": "Thr", "end_pos": 838, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr838", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4LHY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 728, "chemical_mass": 77510.0, "gene_names": "Lnk;CG 17367;CG17367;CG5908;Dmel\\CG17367;Dmel_CG17367;LNK;Lnk;SH2B;dSH2B;lnk", "protein_name": "", "disease": [ { "disease_id": "DOID:0060398", "name": "chromosome 16p11.2 deletion syndrome, 220-kb", "description": "A chromosomal deletion syndrome that is characterized by developmental delay, mild intellectual disability and autism spectrum disorder and that has_material_basis_in a partial deletion of the short arm of chromosome 16, specifically a deletion of a 220-kb region on chromosome 16p11.2 (chr16:28.73-28.95 Mb) encompassing approximately 9 genes, including the SH2B1 gene.", "url": "https://disease-ontology.org/term/DOID:0060398", "evidence": [ { "id": "0060398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060398" } ], "weight": 0.0 }, { "disease_id": "DOID:0060652", "name": "familial erythrocytosis 1", "description": "A primary polycythemia that has_material_basis_in mutation in the gene encoding the erythropoietin receptor. It is characterized by increased serum red blood cell mass and hemoglobin concentration, hypersensitivity of erythroid progenitors to EPO, and low serum levels of EPO.", "url": "https://disease-ontology.org/term/DOID:0060652", "evidence": [ { "id": "0060652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060652" } ], "weight": 0.0 }, { "disease_id": "DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.", "url": "https://disease-ontology.org/term/DOID:0080199", "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ], "weight": 0.0 }, { "disease_id": "DOID:2224", "name": "essential thrombocythemia", "description": "A myeloproliferative neoplasm that is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage and that results_in the overproduction of platelets.", "url": "https://disease-ontology.org/term/DOID:2224", "evidence": [ { "id": "2224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2224" } ], "weight": 0.0 }, { "disease_id": "DOID:4971", "name": "myelofibrosis", "description": "A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.", "url": "https://disease-ontology.org/term/DOID:4971", "evidence": [ { "id": "4971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4971" } ], "weight": 0.0 }, { "disease_id": "DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells.", "url": "https://disease-ontology.org/term/DOID:8552", "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 }, { "disease_id": "DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.", "url": "https://disease-ontology.org/term/DOID:9744", "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ], "weight": 0.0 } ], "biological_process": [ { "name": "female mating behavior", "id": "GO:0060180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060180", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "regulation of growth", "id": "GO:0040008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040008", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "carbohydrate homeostasis", "id": "GO:0033500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033500", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "positive regulation of protein localization to cell cortex", "id": "GO:1904778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904778", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" } ], "molecular_function": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase adaptor activity", "id": "GO:0005068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005068", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LHY5", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4LHY5-1", "start_pos": "22", "end_pos": "22", "site_lbl": "Thr22", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "A0A0B4LHY5-1", "start_pos": "400", "end_pos": "400", "site_lbl": "Thr400", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 400, "start_aa": "Thr", "end_pos": 400, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr400", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JCX9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 218, "chemical_mass": 24511.0, "gene_names": "Ptth;CG13687;Dmel\\CG13687;Dmel_CG13687;PTTH;Ptth;ptth", "protein_name": "", "disease": [], "cellular_component": [ { "name": "varicosity", "id": "GO:0043196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043196", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" } ], "molecular_function": [ { "name": "prothoracicotrophic hormone activity", "id": "GO:0018445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018445", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" } ], "biological_process": [ { "name": "negative phototaxis", "id": "GO:0046957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046957", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" }, { "name": "metamorphosis", "id": "GO:0007552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007552", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" }, { "name": "torso signaling pathway", "id": "GO:0008293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008293", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" }, { "name": "positive regulation of ecdysteroid biosynthetic process", "id": "GO:0045998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045998", "evidence": [ { "database": "UniProtKB", "id": "X2JCX9", "url": "https://www.uniprot.org/uniprotkb/X2JCX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4KFE4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 728, "chemical_mass": 81815.0, "gene_names": "Acsl;4;7447;ACSL1;ACSL3/4;ACSL3;ACS;Acsl;CG8732;Dmel\\CG8732;Dmel_CG8732;FACS;FCS;acsl;anon-WO0172774.173;dAcsl;dFAC;l(2)05847;l(2)44DEa;l(2)7447;l(2)SH0465;l(2)SH2 0465;l(2)k05304", "protein_name": "long-chain-fatty-acid--CoA ligase", "disease": [ { "disease_id": "DOID:0050776", "name": "non-syndromic X-linked intellectual disability", "description": "A non-syndromic intellectual disability characterized by a X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0050776", "evidence": [ { "id": "0050776", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050776" } ], "weight": 0.0 }, { "disease_id": "DOID:0112050", "name": "non-syndromic X-linked intellectual disability 63", "description": "A non-syndromic X-linked intellectual disability characterized by moderate to severe nonprogressive intellectual disability in males and moderate intellectual disability to normal intelligence in females that has_material_basis_in heterozygous mutation in the ACSL4 gene on chromosome Xq23.", "url": "https://disease-ontology.org/term/DOID:0112050", "evidence": [ { "id": "0112050", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112050" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills.", "url": "https://disease-ontology.org/term/DOID:1059", "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ], "weight": 0.0 }, { "disease_id": "DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung.", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ], "weight": 0.0 }, { "disease_id": "DOID:14501", "name": "Sjogren-Larsson syndrome", "description": "A syndrome that is characterized by ichthyosis, mental retardation, spastic paraparesis, macular dystrophy, and leukoencephalopathy, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the aldehyde dehydrogenase 3 family member A2 (ALDH3A2) gene, which encodes fatty aldehyde dehydrogenase, on chromosome 17p11.", "url": "https://disease-ontology.org/term/DOID:14501", "evidence": [ { "id": "14501", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14501" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "long-chain fatty acid-CoA ligase activity", "id": "GO:0004467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004467", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "palmitoyl-CoA ligase activity", "id": "GO:0090433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090433", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" } ], "biological_process": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "segmentation", "id": "GO:0035282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035282", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "positive regulation of triglyceride storage", "id": "GO:0010890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010890", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "long-chain fatty-acyl-CoA biosynthetic process", "id": "GO:0035338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035338", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "long-chain fatty-acyl-CoA metabolic process", "id": "GO:0035336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035336", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" }, { "name": "phosphatidylglycerol biosynthetic process", "id": "GO:0006655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006655", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KFE4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFE4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A1ZBW0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 502, "chemical_mass": 51022.0, "gene_names": "HnRNP-K;BL;Bancal;Bl;CG13425;Dmel\\CG13425;Dmel_CG13425;HnRNP-K;Hrb57A;Q18;bl;dhnRNP K;hnRNP K;hnRNP-A1L;hrb57a;l(2)k08305", "protein_name": "", "disease": [ { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10300", "name": "Raynaud disease", "description": "A peripheral vascular disease that is characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or cyanosis in response to cold exposure or stress.", "url": "https://disease-ontology.org/term/DOID:10300", "evidence": [ { "id": "10300", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10300" } ], "weight": 0.0 }, { "disease_id": "DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:9256", "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "omega speckle", "id": "GO:0035062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035062", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A1ZBW0", "url": "https://www.uniprot.org/uniprotkb/A1ZBW0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JEJ0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 551, "chemical_mass": 62529.0, "gene_names": "Dmel\\CG1440;CG1440;Dmel\\CG1440;Dmel_CG1440", "protein_name": "Bleomycin hydrolase", "disease": [], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "homocysteine catabolic process", "id": "GO:0043418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043418", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" } ], "molecular_function": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "cysteine-type aminopeptidase activity", "id": "GO:0070005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070005", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" }, { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "X2JEJ0", "url": "https://www.uniprot.org/uniprotkb/X2JEJ0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VYF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYF5", "url": "https://www.uniprot.org/uniprotkb/Q9VYF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 203, "chemical_mass": 23669.0, "gene_names": "Dmel\\CG15742;CG15742;Dmel\\CG15742;Dmel_CG15742", "protein_name": "CG15742-PA", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9W2H8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1629, "chemical_mass": 183219.0, "gene_names": "Agl;BEST:GH22856;CG9485;Dmel\\CG9485;Dmel_CG9485", "protein_name": "Glycogen debranching enzyme", "disease": [ { "disease_id": "DOID:2748", "name": "glycogen storage disease III", "description": "A glycogen storage disease that is characterized by an accumulation of abnormal glycogen with short outer chains and that has_material_basis_in homozygous or compound heterozygous mutation in the AGL gene, which encodes the glycogen debrancher enzyme, on chromosome 1p21.", "url": "https://disease-ontology.org/term/DOID:2748", "evidence": [ { "id": "2748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2748" } ], "weight": 0.0 }, { "disease_id": "DOID:4676", "name": "uremia", "description": "", "url": "https://disease-ontology.org/term/DOID:4676", "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ], "weight": 0.0 }, { "disease_id": "DOID:5212", "name": "congenital disorder of glycosylation", "description": "A carbohydrate metabolic disorder that involves deficient or defective glycosylation of a variety of tissue proteins and/or lipids.", "url": "https://disease-ontology.org/term/DOID:5212", "evidence": [ { "id": "5212", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5212" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "4-alpha-glucanotransferase activity", "id": "GO:0004134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004134", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" }, { "name": "amylo-alpha-1,6-glucosidase activity", "id": "GO:0004135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004135", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" } ], "biological_process": [ { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" }, { "name": "glycogen catabolic process", "id": "GO:0005980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005980", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H8", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVE0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 145, "chemical_mass": 17055.0, "gene_names": "Pop5;CG14057;Dmel\\CG14057;Dmel_CG14057;Pop5", "protein_name": "Ribonuclease P/MRP protein subunit POP5", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "ribonuclease P complex", "id": "GO:0030677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030677", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "multimeric ribonuclease P complex", "id": "GO:0030681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030681", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" } ], "biological_process": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" } ], "molecular_function": [ { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VVE0", "url": "https://www.uniprot.org/uniprotkb/Q9VVE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JAR4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JAR4", "url": "https://www.uniprot.org/uniprotkb/X2JAR4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 254, "chemical_mass": 28273.0, "gene_names": "Dmel\\CG42780;CG42780;Dmel\\CG42780;Dmel_CG42780", "protein_name": "SCP domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "X2JAR4", "url": "https://www.uniprot.org/uniprotkb/X2JAR4" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "X2JAR4", "url": "https://www.uniprot.org/uniprotkb/X2JAR4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VT40-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 818, "chemical_mass": 91503.0, "gene_names": "nbs;6754;CG6754;Dmel\\CG6754;Dmel_CG6754;Dnbs1;NBS1;NBS;Nbs1;Nbs;dNbs1;l(3)67BDp;l(3)67BDr;l(3)e77A1;nbs1;nbs", "protein_name": "Nibrin", "disease": [ { "disease_id": "DOID:0014667", "name": "disease of metabolism", "description": "A disease that involves errors in metabolic processes of building or degradation of molecules.", "url": "https://disease-ontology.org/term/DOID:0014667", "evidence": [ { "id": "0014667", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0014667" } ], "weight": 0.0 }, { "disease_id": "DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate.", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ], "weight": 0.0 }, { "disease_id": "DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.", "url": "https://disease-ontology.org/term/DOID:10652", "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ], "weight": 0.0 }, { "disease_id": "DOID:12449", "name": "aplastic anemia", "description": "A normocytic anemia that is characterized by a deficiency of red blood cells, white blood cells and platelets produced by bone marrow.", "url": "https://disease-ontology.org/term/DOID:12449", "evidence": [ { "id": "12449", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12449" } ], "weight": 0.0 }, { "disease_id": "DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland.", "url": "https://disease-ontology.org/term/DOID:1612", "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ], "weight": 0.0 }, { "disease_id": "DOID:1993", "name": "rectum cancer", "description": "A colorectal cancer that is located_in the rectum.", "url": "https://disease-ontology.org/term/DOID:1993", "evidence": [ { "id": "1993", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1993" } ], "weight": 0.0 }, { "disease_id": "DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary.", "url": "https://disease-ontology.org/term/DOID:2394", "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ], "weight": 0.0 }, { "disease_id": "DOID:5603", "name": "T-cell acute lymphoblastic leukemia", "description": "An acute lymphoblastic leukemia that is characterized by too many T-cell lymphoblasts found in the bone marrow and blood.", "url": "https://disease-ontology.org/term/DOID:5603", "evidence": [ { "id": "5603", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5603" } ], "weight": 0.0 }, { "disease_id": "DOID:7400", "name": "Nijmegen breakage syndrome", "description": "A syndrome characterized by chromosomal instability, microcephaly, growth retardation, immunodeficiency, cellular hypersensitivity to X-rays, and predisposition to cancer that has_material_basis_in homozygous or compound heterozygous mutation in NBN on chromosome 8q21.3.", "url": "https://disease-ontology.org/term/DOID:7400", "evidence": [ { "id": "7400", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7400" } ], "weight": 0.0 }, { "disease_id": "DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts.", "url": "https://disease-ontology.org/term/DOID:9952", "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ], "weight": 0.0 } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "signal transduction in response to DNA damage", "id": "GO:0042770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042770", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "double-strand break repair via synthesis-dependent strand annealing", "id": "GO:0045003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045003", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "DNA double-strand break processing", "id": "GO:0000729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000729", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" } ], "cellular_component": [ { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "Mre11 complex", "id": "GO:0030870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030870", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" } ], "molecular_function": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q9VT40", "url": "https://www.uniprot.org/uniprotkb/Q9VT40" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VZT7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1381, "chemical_mass": 157513.0, "gene_names": "Girdin;CG12734;Dmel\\CG12734;Dmel_CG12734;Girdin;girdin;mecA", "protein_name": "", "disease": [ { "disease_id": "DOID:0050986", "name": "spinocerebellar ataxia 40", "description": "An autosomal dominant cerebellar ataxia that is characterized by progressive gait abnormalities, dysarthria, tremor and hyporeflexia, has_material_basis_in mutation in the CCDC88C gene.", "url": "https://disease-ontology.org/term/DOID:0050986", "evidence": [ { "id": "0050986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050986" } ], "weight": 0.0 }, { "disease_id": "DOID:10908", "name": "hydrocephalus", "description": "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.", "url": "https://disease-ontology.org/term/DOID:10908", "evidence": [ { "id": "10908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10908" } ], "weight": 0.0 } ], "biological_process": [ { "name": "epithelium migration", "id": "GO:0090132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090132", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "dendrite morphogenesis", "id": "GO:0048813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048813", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "positive regulation of cell size", "id": "GO:0045793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045793", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "cytoskeleton-dependent intracellular transport", "id": "GO:0030705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030705", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "epithelial cell-cell adhesion", "id": "GO:0090136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090136", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "zonula adherens", "id": "GO:0005915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005915", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "spot adherens junction", "id": "GO:0005914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005914", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "sensory dendrite", "id": "GO:0071683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071683", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" } ], "molecular_function": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "Q9VZT7", "url": "https://www.uniprot.org/uniprotkb/Q9VZT7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VZT7-1", "start_pos": "1280", "end_pos": "1280", "site_lbl": "Thr1280", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1280, "start_aa": "Thr", "end_pos": 1280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1280", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZT7-1", "start_pos": "1301", "end_pos": "1301", "site_lbl": "Thr1301", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1301, "start_aa": "Thr", "end_pos": 1301, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1301", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VZT7-1", "start_pos": "239", "end_pos": "239", "site_lbl": "Thr239", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 239, "start_aa": "Thr", "end_pos": 239, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr239", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VUG6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUG6", "url": "https://www.uniprot.org/uniprotkb/Q9VUG6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1333, "chemical_mass": 153969.0, "gene_names": "Dmel\\CG17177;CG17177;Dmel\\CG17177;Dmel_CG17177", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VUG6-1", "start_pos": "290", "end_pos": "290", "site_lbl": "Thr290", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VUG6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VUG6" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JAG8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 912, "chemical_mass": 104626.0, "gene_names": "Prp4k;BcDNA:GH04978;CG7028;Dmel\\CG7028;Dmel_CG7028;PRP4K;PRP4;Prp4k;prp4", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "disease": [], "molecular_function": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" } ], "cellular_component": [ { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "mRNA cis splicing, via spliceosome", "id": "GO:0045292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045292", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" }, { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "X2JAG8", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JAG8-1", "start_pos": "263", "end_pos": "263", "site_lbl": "Thr263", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAG8-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JAG8-1", "start_pos": "498", "end_pos": "498", "site_lbl": "Thr498", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JAX9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JAX9", "url": "https://www.uniprot.org/uniprotkb/X2JAX9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 589, "chemical_mass": 62924.0, "gene_names": "ect;CG11965;CG6611;DROECT;Difl;Dmel\\CG6611;Dmel_CG6611;Ifl;ect", "protein_name": "", "disease": [], "biological_process": [ { "name": "tube development", "id": "GO:0035295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035295", "evidence": [ { "database": "UniProtKB", "id": "X2JAX9", "url": "https://www.uniprot.org/uniprotkb/X2JAX9" } ], "pmid": "" }, { "name": "cuticle development", "id": "GO:0042335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042335", "evidence": [ { "database": "UniProtKB", "id": "X2JAX9", "url": "https://www.uniprot.org/uniprotkb/X2JAX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VUR8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUR8", "url": "https://www.uniprot.org/uniprotkb/Q9VUR8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 570, "chemical_mass": 64895.0, "gene_names": "Dmel\\CG13449;CG13449;Dmel\\CG13449;Dmel_CG13449", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VUR8-1", "start_pos": "131", "end_pos": "131", "site_lbl": "Thr131", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VUR8-1", "start_pos": "133", "end_pos": "133", "site_lbl": "Thr133", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 133, "start_aa": "Thr", "end_pos": 133, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr133", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VX92-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1552, "chemical_mass": 174299.0, "gene_names": "RhoGAP15B;CG4937;Dmel\\CG4937;Dmel_CG4937;RhoGAP15B;gap20", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "generation of neurons", "id": "GO:0048699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048699", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "Q9VX92", "url": "https://www.uniprot.org/uniprotkb/Q9VX92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VX92-1", "start_pos": "1429", "end_pos": "1429", "site_lbl": "Thr1429", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1429, "start_aa": "Thr", "end_pos": 1429, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1429", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VU18-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 804, "chemical_mass": 90080.0, "gene_names": "CT30663;CG10948;CT30663;Dmel\\CG10948;Dmel_CG10948;cg10948", "protein_name": "RRM domain-containing protein", "disease": [], "molecular_function": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" } ], "cellular_component": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" } ], "biological_process": [ { "name": "ultradian rhythm", "id": "GO:0007624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007624", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "Q9VU18", "url": "https://www.uniprot.org/uniprotkb/Q9VU18" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VU18-1", "start_pos": "199", "end_pos": "199", "site_lbl": "Thr199", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9W523-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1537, "chemical_mass": 161977.0, "gene_names": "ph-d;CG3895;DROZFP;Dmel\\CG3895;Dmel_CG3895;EG:BACN25G24.3;PH-d;PHD;PH;Ph-d;PhD;Ph;ph-D;ph-d;ph[D];ph[d];phd;phm;ph", "protein_name": "", "disease": [ { "disease_id": "DOID:0070287", "name": "primary autosomal recessive microcephaly 11", "description": "A primary autosomal recessive microcephaly that has_material_basis_in homozygous or compound heterozygous mutation in the PHC1 gene on chromosome 12p13.", "url": "https://disease-ontology.org/term/DOID:0070287", "evidence": [ { "id": "0070287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070287" } ], "weight": 0.0 }, { "disease_id": "DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently.", "url": "https://disease-ontology.org/term/DOID:12930", "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 }, { "disease_id": "DOID:6419", "name": "tetralogy of Fallot", "description": "", "url": "https://disease-ontology.org/term/DOID:6419", "evidence": [ { "id": "6419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6419" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "polytene chromosome", "id": "GO:0005700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005700", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" } ], "biological_process": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "syncytial blastoderm mitotic cell cycle", "id": "GO:0035186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035186", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "Q9W523", "url": "https://www.uniprot.org/uniprotkb/Q9W523" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9W523-1", "start_pos": "1051", "end_pos": "1051", "site_lbl": "Thr1051", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1051, "start_aa": "Thr", "end_pos": 1051, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1051", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W523-1", "start_pos": "1085", "end_pos": "1085", "site_lbl": "Thr1085", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1085, "start_aa": "Thr", "end_pos": 1085, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1085", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W523-1", "start_pos": "1433", "end_pos": "1433", "site_lbl": "Thr1433", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1433, "start_aa": "Thr", "end_pos": 1433, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1433", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9W523-1", "start_pos": "89", "end_pos": "89", "site_lbl": "Thr89", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A8JRE3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1703, "chemical_mass": 188738.0, "gene_names": "woc;CG5965;Dmel\\CG5965;Dmel_CG5965;WOC;Woc;woc", "protein_name": "", "disease": [ { "disease_id": "DOID:0050776", "name": "non-syndromic X-linked intellectual disability", "description": "A non-syndromic intellectual disability characterized by a X-linked inheritance pattern.", "url": "https://disease-ontology.org/term/DOID:0050776", "evidence": [ { "id": "0050776", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050776" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "ecdysone biosynthetic process", "id": "GO:0006697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006697", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" } ], "cellular_component": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "polytene chromosome interband", "id": "GO:0005705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005705", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A8JRE3", "url": "https://www.uniprot.org/uniprotkb/A8JRE3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A8JRE3-1", "start_pos": "1085", "end_pos": "1085", "site_lbl": "Thr1085", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1085, "start_aa": "Thr", "end_pos": 1085, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1085", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "A0A0B4LIC4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 880, "chemical_mass": 92528.0, "gene_names": "Dmel\\CG15803;lincRNA.804;CG15803;Dmel\\CG15803;Dmel_CG15803;lincRNA.804", "protein_name": "PDZ domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4LIC4", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LIC4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "A0A0B4LIC4-1", "start_pos": "596", "end_pos": "596", "site_lbl": "Thr596", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 596, "start_aa": "Thr", "end_pos": 596, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr596", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2J9P4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 940, "chemical_mass": 105730.0, "gene_names": "Dpp10;CG11319;DPP10;Dmel\\CG11319;Dmel_CG11319;Dpp10", "protein_name": "Venom dipeptidyl peptidase 4", "disease": [ { "disease_id": "DOID:0070063", "name": "autosomal dominant intellectual developmental disorder 33", "description": "An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the DPP6 gene on chromosome 7q36.2.", "url": "https://disease-ontology.org/term/DOID:0070063", "evidence": [ { "id": "0070063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070063" } ], "weight": 0.0 }, { "disease_id": "DOID:12377", "name": "spinal muscular atrophy", "description": "A motor neuron disease that is a degenerative neuromuscular disease characterized by lower motor neuron degeneration associated with progressive muscle weakness and atrophy.", "url": "https://disease-ontology.org/term/DOID:12377", "evidence": [ { "id": "12377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12377" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.", "url": "https://disease-ontology.org/term/DOID:332", "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ], "weight": 0.0 } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "regulation of potassium ion transmembrane transport", "id": "GO:1901379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901379", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "Kv4.3-DPP10 channel complex", "id": "GO:0071202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071202", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" } ], "molecular_function": [ { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "dipeptidyl-peptidase activity", "id": "GO:0008239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008239", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "X2J9P4", "url": "https://www.uniprot.org/uniprotkb/X2J9P4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2J9P4-1", "start_pos": "621", "end_pos": "621", "site_lbl": "Thr621", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 621, "start_aa": "Thr", "end_pos": 621, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr621", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPI7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPI7", "url": "https://www.uniprot.org/uniprotkb/Q9VPI7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 401, "chemical_mass": 46753.0, "gene_names": "Dmel\\CG11374;CG11374;Dmel\\CG11374;Dmel_CG11374", "protein_name": "Galectin", "disease": [], "molecular_function": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI7", "url": "https://www.uniprot.org/uniprotkb/Q9VPI7" } ], "pmid": "" }, { "name": "galactoside binding", "id": "GO:0016936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016936", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI7", "url": "https://www.uniprot.org/uniprotkb/Q9VPI7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VPI7-1", "start_pos": "271", "end_pos": "271", "site_lbl": "Thr271", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 271, "start_aa": "Thr", "end_pos": 271, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr271", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPJ1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 649, "chemical_mass": 71283.0, "gene_names": "Nhe1;CG12178;DmNHE1;Dmel\\CG12178;Dmel_CG12178;NHE1;Nhe1;nhe1", "protein_name": "Sodium/hydrogen exchanger", "disease": [], "molecular_function": [ { "name": "sodium:proton antiporter activity", "id": "GO:0015385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" }, { "name": "potassium:proton antiporter activity", "id": "GO:0015386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" } ], "cellular_component": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "Q9VPJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VPJ1" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPL8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPL8", "url": "https://www.uniprot.org/uniprotkb/Q9VPL8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 443, "chemical_mass": 51460.0, "gene_names": "Dmel\\CG13693;CG13693;Dmel\\CG13693;Dmel_CG13693", "protein_name": "Cilia- and flagella-associated protein 263", "disease": [], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VPL8", "url": "https://www.uniprot.org/uniprotkb/Q9VPL8" } ], "pmid": "" } ], "cellular_component": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q9VPL8", "url": "https://www.uniprot.org/uniprotkb/Q9VPL8" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VPL8", "url": "https://www.uniprot.org/uniprotkb/Q9VPL8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPN8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 277, "chemical_mass": 30136.0, "gene_names": "SP103;CG11911;Dmel\\CG11911;Dmel_CG11911;SP103", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN8", "url": "https://www.uniprot.org/uniprotkb/Q9VPN8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPP9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 549, "chemical_mass": 60746.0, "gene_names": "BBS8;BBS2;BBS8;CG13691;Dmel\\CG13691;Dmel_CG13691", "protein_name": "", "disease": [ { "disease_id": "DOID:0060340", "name": "ciliopathy", "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia.", "url": "https://disease-ontology.org/term/DOID:0060340", "evidence": [ { "id": "0060340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060340" } ], "weight": 0.0 }, { "disease_id": "DOID:0110130", "name": "Bardet-Biedl syndrome 8", "description": "A Bardet-Biedl syndrome that has_material_basis_in homozygous mutation in the TTC8 gene on chromosome 14q31.", "url": "https://disease-ontology.org/term/DOID:0110130", "evidence": [ { "id": "0110130", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110130" } ], "weight": 0.0 }, { "disease_id": "DOID:0110398", "name": "retinitis pigmentosa 51", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the TTC8 gene on chromosome 14q31.", "url": "https://disease-ontology.org/term/DOID:0110398", "evidence": [ { "id": "0110398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110398" } ], "weight": 0.0 }, { "disease_id": "DOID:1935", "name": "Bardet-Biedl syndrome", "description": "A syndrome that results from mutations in multiple BBS genes affecting cellular cilia structure or function (ciliopathy) resulting in variable presentation and characterized principally by obesity, retinitis pigmentosa,vision loss, polydactyly, mental retardation, hypogonadism, and renal failure in some cases.", "url": "https://disease-ontology.org/term/DOID:1935", "evidence": [ { "id": "1935", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1935" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" }, { "name": "BBSome", "id": "GO:0034464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034464", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" } ], "biological_process": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP9", "url": "https://www.uniprot.org/uniprotkb/Q9VPP9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPS9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPS9", "url": "https://www.uniprot.org/uniprotkb/Q9VPS9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 99, "chemical_mass": 9605.0, "gene_names": "Dmel\\CG13946;CG13946;Dmel\\CG13946;Dmel_CG13946", "protein_name": "Tenecin-3-like", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPW6-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 264, "chemical_mass": 29928.0, "gene_names": "Dmel\\CG14340;CG14340;Dmel\\CG14340;Dmel_CG14340", "protein_name": "", "disease": [], "biological_process": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW6", "url": "https://www.uniprot.org/uniprotkb/Q9VPW6" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VPW9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 689, "chemical_mass": 77472.0, "gene_names": "TBC1D23;CG4552;Dmel\\CG4552;Dmel_CG4552;TBC1D23;tbc1", "protein_name": "TBC1 domain family member 23", "disease": [ { "disease_id": "DOID:0060264", "name": "pontocerebellar hypoplasia", "description": "A neurodegenerative disease that is characterized by underdevelopment of the pons and cerebellum.", "url": "https://disease-ontology.org/term/DOID:0060264", "evidence": [ { "id": "0060264", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060264" } ], "weight": 0.0 }, { "disease_id": "DOID:0112324", "name": "pontocerebellar hypoplasia type 11", "description": "A pontocerebellar hypoplasia characterized by severely delayed psychomotor development with intellectual disability and poor speech, microcephaly, dysmorphic features, and pontocerebellar hypoplasia on brain imaging that has_material_basis_in homozygous or compound heterozygous mutation in the TBC1D23 gene on chromosome 3q12.1-q12.2.", "url": "https://disease-ontology.org/term/DOID:0112324", "evidence": [ { "id": "0112324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112324" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" } ], "biological_process": [ { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" }, { "name": "vesicle tethering to Golgi", "id": "GO:0099041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099041", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" }, { "name": "positive regulation of intracellular transport", "id": "GO:0032388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032388", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW9", "url": "https://www.uniprot.org/uniprotkb/Q9VPW9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VQ50-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQ50", "url": "https://www.uniprot.org/uniprotkb/Q9VQ50" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 673, "chemical_mass": 78460.0, "gene_names": "gi22945479;CG15622;CG31933;Dmel\\CG31933;Dmel_CG31933;gi21064045;gi22945479", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VQ88-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQ88", "url": "https://www.uniprot.org/uniprotkb/Q9VQ88" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 77, "chemical_mass": 8563.0, "gene_names": "Dmel\\CG15386;CG15386;Dmel\\CG15386;Dmel_CG15386", "protein_name": "", "disease": [], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ88", "url": "https://www.uniprot.org/uniprotkb/Q9VQ88" } ], "pmid": "" } ], "biological_process": [ { "name": "mitochondrial respiratory chain complex III assembly", "id": "GO:0034551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034551", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ88", "url": "https://www.uniprot.org/uniprotkb/Q9VQ88" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VQA4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQA4", "url": "https://www.uniprot.org/uniprotkb/Q9VQA4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 242, "chemical_mass": 26991.0, "gene_names": "Dmel\\CG4271;CG4271;Dmel\\CG4271;Dmel_CG4271;SPH164", "protein_name": "trypsin", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VQA4", "url": "https://www.uniprot.org/uniprotkb/Q9VQA4" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VQA4", "url": "https://www.uniprot.org/uniprotkb/Q9VQA4" } ], "pmid": "" } ], "molecular_function": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VQA4", "url": "https://www.uniprot.org/uniprotkb/Q9VQA4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VQD0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 235, "chemical_mass": 27908.0, "gene_names": "Dmel\\CG3528;CG3528;Dmel\\CG3528;Dmel_CG3528", "protein_name": "Cilia- and flagella-associated protein 299", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "pmid": "" } ], "biological_process": [ { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD0", "url": "https://www.uniprot.org/uniprotkb/Q9VQD0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VQH8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQH8", "url": "https://www.uniprot.org/uniprotkb/Q9VQH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 343, "chemical_mass": 37881.0, "gene_names": "c-SPH125;CG18557;Dmel\\CG18557;Dmel_CG18557;c-SPH125;cSPH125", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VQH8", "url": "https://www.uniprot.org/uniprotkb/Q9VQH8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VQH8", "url": "https://www.uniprot.org/uniprotkb/Q9VQH8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VQH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQH9", "url": "https://www.uniprot.org/uniprotkb/Q9VQH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 347, "chemical_mass": 37884.0, "gene_names": "c-SPH94;CG3117;Dmel\\CG3117;Dmel_CG3117;SPH94;c-SPH94;cSPH94", "protein_name": "Phenoloxidase-activating factor 2", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VQH9", "url": "https://www.uniprot.org/uniprotkb/Q9VQH9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VQH9", "url": "https://www.uniprot.org/uniprotkb/Q9VQH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VQL9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 336, "chemical_mass": 38322.0, "gene_names": "PpD6;CG8822;D6;Dmel\\CG8822;Dmel_CG8822;PP1;PPD6;PpD6", "protein_name": "Serine/threonine-protein phosphatase", "disease": [], "biological_process": [ { "name": "male meiosis chromosome segregation", "id": "GO:0007060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007060", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "egg-laying behavior", "id": "GO:0018991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018991", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "regulation of pseudopodium assembly", "id": "GO:0031272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031272", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "amoeboid sperm motility", "id": "GO:0097723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097723", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "pseudopodium", "id": "GO:0031143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031143", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q9VQL9", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VQP2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 466, "chemical_mass": 51764.0, "gene_names": "Dmel\\CG15408;CG15408;Dmel\\CG15408;Dmel_CG15408", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [], "molecular_function": [ { "name": "sugar transmembrane transporter activity", "id": "GO:0051119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051119", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" } ], "biological_process": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9VQP2", "url": "https://www.uniprot.org/uniprotkb/Q9VQP2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "R9PY49-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "R9PY49", "url": "https://www.uniprot.org/uniprotkb/R9PY49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 723, "chemical_mass": 83814.0, "gene_names": "Dmel\\CG8851;CG8851;Dmel\\CG8851;Dmel_CG8851", "protein_name": "", "disease": [], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "R9PY49", "url": "https://www.uniprot.org/uniprotkb/R9PY49" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "R9PY49", "url": "https://www.uniprot.org/uniprotkb/R9PY49" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VR48-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR48", "url": "https://www.uniprot.org/uniprotkb/Q9VR48" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 846, "chemical_mass": 94691.0, "gene_names": "hoe2;CG15624;Dmel\\CG15624;Dmel_CG15624;hoe2", "protein_name": "", "disease": [ { "disease_id": "DOID:0050632", "name": "oculocutaneous albinism", "description": "A syndrome characterized by abnormal pigmentation of the skin, hair and eyes.", "url": "https://disease-ontology.org/term/DOID:0050632", "evidence": [ { "id": "0050632", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050632" } ], "weight": 0.0 }, { "disease_id": "DOID:0070096", "name": "oculocutaneous albinism type II", "description": "An oculocutaneous albinism that has_material_basis_in an autosomal recessive mutation of the OCA2 gene on chromosome 15q12-q13.", "url": "https://disease-ontology.org/term/DOID:0070096", "evidence": [ { "id": "0070096", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070096" } ], "weight": 0.0 }, { "disease_id": "DOID:10123", "name": "pigmentation disease", "description": "A skin disease that is characterized by discoloration of the skin.", "url": "https://disease-ontology.org/term/DOID:10123", "evidence": [ { "id": "10123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10123" } ], "weight": 0.0 }, { "disease_id": "DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells.", "url": "https://disease-ontology.org/term/DOID:1749", "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ], "weight": 0.0 }, { "disease_id": "DOID:2513", "name": "basal cell carcinoma", "description": "A skin carcinoma affecting basal cells.", "url": "https://disease-ontology.org/term/DOID:2513", "evidence": [ { "id": "2513", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2513" } ], "weight": 0.0 }, { "disease_id": "DOID:8866", "name": "actinic keratosis", "description": "", "url": "https://disease-ontology.org/term/DOID:8866", "evidence": [ { "id": "8866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8866" } ], "weight": 0.0 }, { "disease_id": "DOID:8923", "name": "skin melanoma", "description": "A skin cancer that has_material_basis_in melanocytes.", "url": "https://disease-ontology.org/term/DOID:8923", "evidence": [ { "id": "8923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8923" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VR48", "url": "https://www.uniprot.org/uniprotkb/Q9VR48" } ], "pmid": "" } ], "molecular_function": [ { "name": "monoatomic ion transmembrane transporter activity", "id": "GO:0015075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015075", "evidence": [ { "database": "UniProtKB", "id": "Q9VR48", "url": "https://www.uniprot.org/uniprotkb/Q9VR48" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VR92-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR92", "url": "https://www.uniprot.org/uniprotkb/Q9VR92" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 302, "chemical_mass": 32593.0, "gene_names": "Dmel\\CG15459;CG15459;Dmel\\CG15459;Dmel_CG15459", "protein_name": "", "disease": [ { "disease_id": "DOID:0111749", "name": "mitochondrial complex V (ATP synthase) deficiency nuclear type 6", "description": "A mitochondrial complex V (ATP synthase) deficiency characterized by episodic regression of gross motor skills beginning in early childhood that has_material_basis_in homozygous or compound heterozygous mutation in the ATP5MD gene on chromosome 10q24.33.", "url": "https://disease-ontology.org/term/DOID:0111749", "evidence": [ { "id": "0111749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111749" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VR92", "url": "https://www.uniprot.org/uniprotkb/Q9VR92" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "Q9VR92", "url": "https://www.uniprot.org/uniprotkb/Q9VR92" } ], "pmid": "" } ], "biological_process": [ { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "Q9VR92", "url": "https://www.uniprot.org/uniprotkb/Q9VR92" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VR92-1", "start_pos": "117", "end_pos": "117", "site_lbl": "Thr117", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 117, "start_aa": "Thr", "end_pos": 117, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr117", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VRG5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1655, "chemical_mass": 190269.0, "gene_names": "Dmel\\CG1801;CG1801;DmCG1801;Dmel\\CG1801;Dmel_CG1801", "protein_name": "ABC transporter domain-containing protein", "disease": [], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG5", "url": "https://www.uniprot.org/uniprotkb/Q9VRG5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VRI3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRI3", "url": "https://www.uniprot.org/uniprotkb/Q9VRI3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 183, "chemical_mass": 17014.0, "gene_names": "Dmel\\CG10918;CG10918;Dmel\\CG10918;Dmel_CG10918", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VRI3", "url": "https://www.uniprot.org/uniprotkb/Q9VRI3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VRM0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 542, "chemical_mass": 60814.0, "gene_names": "Lkr;CG10626;DLKR;Dmel\\CG10626;Dmel_CG10626;LK-R;LKR;LkR;Lkr;anon-WO0131005.17;anon-WO0170980.118;anon-WO0170980.119;dLKR;lkr", "protein_name": "", "disease": [], "biological_process": [ { "name": "negative regulation of feeding behavior", "id": "GO:2000252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000252", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" } ], "molecular_function": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "neuropeptide Y receptor activity", "id": "GO:0004983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004983", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "leucokinin receptor activity", "id": "GO:0042071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042071", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM0", "url": "https://www.uniprot.org/uniprotkb/Q9VRM0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRM0-1", "start_pos": "431", "end_pos": "431", "site_lbl": "Thr431", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 431, "start_aa": "Thr", "end_pos": 431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr431", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VRP4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 518, "chemical_mass": 57641.0, "gene_names": "Ppat-Dpck;CG10575;DPCK/PPAT;Dmel\\CG10575;Dmel_CG10575;PPAT-DPCK;PPAT;Ppat-Dpck;dCOASY;dPPAT-DPCK", "protein_name": "Bifunctional coenzyme A synthase", "disease": [ { "disease_id": "DOID:0110740", "name": "neurodegeneration with brain iron accumulation 6", "description": "A neurodegeneration with brain iron accumulation that has_material_basis_in autosomal recessive inheritance of mutation in the COASY gene on chromosome 17q21.2.", "url": "https://disease-ontology.org/term/DOID:0110740", "evidence": [ { "id": "0110740", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110740" } ], "weight": 0.0 }, { "disease_id": "DOID:0112327", "name": "pontocerebellar hypoplasia type 12", "description": "A pontocerebellar hypoplasia that has_material_basis_in homozygous or compound heterozygous mutation in the COASY gene on chromosome 17q21.2.", "url": "https://disease-ontology.org/term/DOID:0112327", "evidence": [ { "id": "0112327", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112327" } ], "weight": 0.0 }, { "disease_id": "DOID:12801", "name": "mucopolysaccharidosis III", "description": "A mucopolysaccharidosis characterized by a deficiency of the lysosomal enzyme resulting in incomplete breakdown of the heparan sulfate sugar chain.", "url": "https://disease-ontology.org/term/DOID:12801", "evidence": [ { "id": "12801", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12801" } ], "weight": 0.0 }, { "disease_id": "DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.", "url": "https://disease-ontology.org/term/DOID:162", "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "dephospho-CoA kinase activity", "id": "GO:0004140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004140", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" }, { "name": "pantetheine-phosphate adenylyltransferase activity", "id": "GO:0004595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004595", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" } ], "biological_process": [ { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" }, { "name": "coenzyme A biosynthetic process", "id": "GO:0015937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015937", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP4", "url": "https://www.uniprot.org/uniprotkb/Q9VRP4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VRP4-1", "start_pos": "229", "end_pos": "229", "site_lbl": "Thr229", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 229, "start_aa": "Thr", "end_pos": 229, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr229", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VRT4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRT4", "url": "https://www.uniprot.org/uniprotkb/Q9VRT4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 662, "chemical_mass": 73186.0, "gene_names": "CG6596;CG42269;CG6596;CG6600;Dmel\\CG42269;Dmel_CG42269", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "disease": [ { "disease_id": "DOID:13619", "name": "extrahepatic cholestasis", "description": "A cholestasis resulting from causes located_in bile ducts outside the liver.", "url": "https://disease-ontology.org/term/DOID:13619", "evidence": [ { "id": "13619", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13619" } ], "weight": 0.0 }, { "disease_id": "DOID:1852", "name": "intrahepatic cholestasis", "description": "A cholestasis characterized by impairment of the bile flow caused by obstruction located_in liver.", "url": "https://disease-ontology.org/term/DOID:1852", "evidence": [ { "id": "1852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1852" } ], "weight": 0.0 }, { "disease_id": "DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.", "url": "https://disease-ontology.org/term/DOID:2841", "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ], "weight": 0.0 }, { "disease_id": "DOID:3021", "name": "acute kidney failure", "description": "", "url": "https://disease-ontology.org/term/DOID:3021", "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRT4", "url": "https://www.uniprot.org/uniprotkb/Q9VRT4" } ], "pmid": "" } ], "molecular_function": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VRT4", "url": "https://www.uniprot.org/uniprotkb/Q9VRT4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VS65-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 344, "chemical_mass": 39884.0, "gene_names": "CG18415;CG18415;CG32379;Dmel\\CG32379;Dmel_CG32379", "protein_name": "Peptidase M14 domain-containing protein", "disease": [ { "disease_id": "DOID:0060752", "name": "familial temporal lobe epilepsy 5", "description": "A temporal lobe epilepsy that has_material_basis_in heterozygous mutation in the CPA6 gene on chromosome 8q13.", "url": "https://disease-ontology.org/term/DOID:0060752", "evidence": [ { "id": "0060752", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060752" } ], "weight": 0.0 }, { "disease_id": "DOID:0111308", "name": "familial febrile seizures 11", "description": "A familial febrile seizures that has_material_basis_in homozygous mutation in the CPA6 gene on chromosome 8p13.2.", "url": "https://disease-ontology.org/term/DOID:0111308", "evidence": [ { "id": "0111308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111308" } ], "weight": 0.0 }, { "disease_id": "DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.", "url": "https://disease-ontology.org/term/DOID:1184", "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ], "weight": 0.0 }, { "disease_id": "DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes.", "url": "https://disease-ontology.org/term/DOID:13241", "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ], "weight": 0.0 }, { "disease_id": "DOID:2228", "name": "thrombocytosis", "description": "A blood platelet disease that is characterized by the presence of high platelet counts in the blood.", "url": "https://disease-ontology.org/term/DOID:2228", "evidence": [ { "id": "2228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2228" } ], "weight": 0.0 }, { "disease_id": "DOID:4989", "name": "pancreatitis", "description": "A pancreas disease that is characterized by inflammation of the pancreas.", "url": "https://disease-ontology.org/term/DOID:4989", "evidence": [ { "id": "4989", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4989" } ], "weight": 0.0 }, { "disease_id": "DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3).", "url": "https://disease-ontology.org/term/DOID:784", "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ], "weight": 0.0 }, { "disease_id": "DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.", "url": "https://disease-ontology.org/term/DOID:9351", "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ], "weight": 0.0 }, { "disease_id": "DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.", "url": "https://disease-ontology.org/term/DOID:9352", "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ], "weight": 0.0 }, { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "Q9VS65", "url": "https://www.uniprot.org/uniprotkb/Q9VS65" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VS81-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS81", "url": "https://www.uniprot.org/uniprotkb/Q9VS81" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 197, "chemical_mass": 21791.0, "gene_names": "Dmel\\CG7548;CG7548;Dmel\\CG7548;Dmel_CG7548", "protein_name": "", "disease": [], "molecular_function": [ { "name": "structural constituent of cuticle", "id": "GO:0042302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042302", "evidence": [ { "database": "UniProtKB", "id": "Q9VS81", "url": "https://www.uniprot.org/uniprotkb/Q9VS81" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VS91-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 728, "chemical_mass": 84012.0, "gene_names": "t-Grip84;CG7716;Dmel\\CG7716;Dmel_CG7716;t-Grip84", "protein_name": "Gamma-tubulin complex component", "disease": [ { "disease_id": "DOID:0081266", "name": "complex cortical dysplasia with other brain malformations 15", "description": "A cortical dysplasia with other brain malformation that is characterized by progressive microcephaly associated with abnormal facial features, hypotonia, and variable global developmental delay with impaired intellectual development and that has_material_basis_in homozygous or compound heterozygous mutation in the TUBGCP2 gene on chromosome 10q26.", "url": "https://disease-ontology.org/term/DOID:0081266", "evidence": [ { "id": "0081266", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081266" } ], "weight": 0.0 } ], "biological_process": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" } ], "cellular_component": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" }, { "name": "gamma-tubulin complex", "id": "GO:0000930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000930", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" } ], "molecular_function": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "Q9VS91", "url": "https://www.uniprot.org/uniprotkb/Q9VS91" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VSJ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 262, "chemical_mass": 28375.0, "gene_names": "Jon66Cii;66C;CCG7170;CG7170;Dmel\\CG7170;Dmel_CG7170;Jon66CII;Jon66Cii;Jon66C;SP165", "protein_name": "trypsin", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VSJ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSJ2" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VSQ2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VSQ2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 401, "chemical_mass": 43433.0, "gene_names": "Dmel\\CG13310;CG13310;Dmel\\CG13310;Dmel_CG13310", "protein_name": "CUB domain-containing protein", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VSQ2-1", "start_pos": "177", "end_pos": "177", "site_lbl": "Thr177", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VSR8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSR8", "url": "https://www.uniprot.org/uniprotkb/Q9VSR8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 476, "chemical_mass": 54036.0, "gene_names": "Dmel\\CG5653;CG5653;Dmel\\CG5653;Dmel_CG5653", "protein_name": "Amine oxidase domain-containing protein", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VSR8", "url": "https://www.uniprot.org/uniprotkb/Q9VSR8" } ], "pmid": "" } ], "molecular_function": [ { "name": "polyamine oxidase activity", "id": "GO:0046592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046592", "evidence": [ { "database": "UniProtKB", "id": "Q9VSR8", "url": "https://www.uniprot.org/uniprotkb/Q9VSR8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VT14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT14", "url": "https://www.uniprot.org/uniprotkb/Q9VT14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 379, "chemical_mass": 44527.0, "gene_names": "bs17c12.y1;CG3222;Dmel\\CG3222;Dmel_CG3222;NEST:bs17c12;bs17c12.y1", "protein_name": "MORN repeat-containing protein 5", "disease": [], "cellular_component": [ { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q9VT14", "url": "https://www.uniprot.org/uniprotkb/Q9VT14" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VT14-1", "start_pos": "130", "end_pos": "130", "site_lbl": "Thr130", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VT23-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 259, "chemical_mass": 27841.0, "gene_names": "SP170;CG8329;Dmel\\CG8329;Dmel_CG8329;SP170", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VT23", "url": "https://www.uniprot.org/uniprotkb/Q9VT23" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VT29-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT29", "url": "https://www.uniprot.org/uniprotkb/Q9VT29" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 300, "chemical_mass": 33580.0, "gene_names": "Mpped;CG16717;Dmel\\CG16717;Dmel_CG16717", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "disease": [], "molecular_function": [ { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "Q9VT29", "url": "https://www.uniprot.org/uniprotkb/Q9VT29" } ], "pmid": "" }, { "name": "cyclic-nucleotide phosphodiesterase activity", "id": "GO:0004112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004112", "evidence": [ { "database": "UniProtKB", "id": "Q9VT29", "url": "https://www.uniprot.org/uniprotkb/Q9VT29" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VT95-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 574, "chemical_mass": 66716.0, "gene_names": "Ir67b;67b;CG12303;DmelIR67b;Dmel\\CG12303;Dmel_CG12303;IR67b;Ir67b", "protein_name": "", "disease": [], "biological_process": [ { "name": "detection of chemical stimulus", "id": "GO:0009593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009593", "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "pmid": "" } ], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "pmid": "" } ], "molecular_function": [ { "name": "ligand-gated monoatomic ion channel activity", "id": "GO:0015276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015276", "evidence": [ { "database": "UniProtKB", "id": "Q9VT95", "url": "https://www.uniprot.org/uniprotkb/Q9VT95" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JGL7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JGL7", "url": "https://www.uniprot.org/uniprotkb/X2JGL7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 458, "chemical_mass": 52178.0, "gene_names": "Sms;CG4300;Dmel\\CG4300;Dmel_CG4300;Sms;anon-WO0118547.387;dSms;sms", "protein_name": "", "disease": [ { "disease_id": "DOID:0060802", "name": "syndromic X-linked intellectual disability Snyder type", "description": "A syndromic X-linked intellectual disability characterized by mild to profound intellectual disability, facial asymmetry, marfanoid habitus, asthenic habitus, unsteady gait, thickened lower lip, nasal dysarthic speech, narrow or cleft palate, osteoporosis, kyphoscoliosis, long great toes, short stature, pectus carinatum, and myopia that has_material_basis_in mutation in the SMS gene on chromosome Xp22.", "url": "https://disease-ontology.org/term/DOID:0060802", "evidence": [ { "id": "0060802", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060802" } ], "weight": 0.0 }, { "disease_id": "DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations.", "url": "https://disease-ontology.org/term/DOID:2030", "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ], "weight": 0.0 } ], "biological_process": [ { "name": "spermine biosynthetic process", "id": "GO:0006597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006597", "evidence": [ { "database": "UniProtKB", "id": "X2JGL7", "url": "https://www.uniprot.org/uniprotkb/X2JGL7" } ], "pmid": "" } ], "molecular_function": [ { "name": "spermine synthase activity", "id": "GO:0016768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016768", "evidence": [ { "database": "UniProtKB", "id": "X2JGL7", "url": "https://www.uniprot.org/uniprotkb/X2JGL7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VU11-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU11", "url": "https://www.uniprot.org/uniprotkb/Q9VU11" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 697, "chemical_mass": 78942.0, "gene_names": "Dmel\\CG10969;CG10969;Dmel\\CG10969;Dmel_CG10969", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VU22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1371, "chemical_mass": 151087.0, "gene_names": "Dmel\\CG14120;CG14120;Dmel\\CG14120;Dmel_CG14120", "protein_name": "DNA/RNA non-specific endonuclease domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" }, { "name": "single-stranded DNA endodeoxyribonuclease activity", "id": "GO:0000014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000014", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" } ], "biological_process": [ { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "Q9VU22", "url": "https://www.uniprot.org/uniprotkb/Q9VU22" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VUJ7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ7", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 167, "chemical_mass": 19103.0, "gene_names": "Dmel\\CG18581;CG18581;Dmel\\CG18581;Dmel_CG18581", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VV12-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV12", "url": "https://www.uniprot.org/uniprotkb/Q9VV12" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 93, "chemical_mass": 9445.0, "gene_names": "Dmel\\CG13066;CG13066;Dmel\\CG13066;Dmel_CG13066", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VV22-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV22", "url": "https://www.uniprot.org/uniprotkb/Q9VV22" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 113, "chemical_mass": 12472.0, "gene_names": "Dmel\\CG4982;CG4982;Dmel\\CG4982;Dmel_CG4982", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VV31-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV31", "url": "https://www.uniprot.org/uniprotkb/Q9VV31" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 155, "chemical_mass": 15844.0, "gene_names": "Dmel\\CG13059;CG13059;Dmel\\CG13059;Dmel_CG13059", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VV94-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV94", "url": "https://www.uniprot.org/uniprotkb/Q9VV94" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 122, "chemical_mass": 12353.0, "gene_names": "Dmel\\CG13031;CG13031;Dmel\\CG13031;Dmel_CG13031", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVA9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1734, "chemical_mass": 197109.0, "gene_names": "Zcchc7;CG9715;Dmel\\CG9715;Dmel_CG9715;Zcchc7;dZcchc7", "protein_name": "Zinc finger CCHC domain-containing protein 7", "disease": [], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" } ], "biological_process": [ { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent rRNA catabolic process", "id": "GO:0071035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071035", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "TRAMP-dependent tRNA surveillance pathway", "id": "GO:0071038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071038", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snoRNA catabolic process", "id": "GO:0071036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071036", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent snRNA catabolic process", "id": "GO:0071037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071037", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear polyadenylation-dependent CUT catabolic process", "id": "GO:0071039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071039", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" }, { "name": "nuclear mRNA surveillance of mRNA 3'-end processing", "id": "GO:0071031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071031", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" } ], "cellular_component": [ { "name": "TRAMP complex", "id": "GO:0031499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031499", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA9", "url": "https://www.uniprot.org/uniprotkb/Q9VVA9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVA9-1", "start_pos": "1526", "end_pos": "1526", "site_lbl": "Thr1526", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1526, "start_aa": "Thr", "end_pos": 1526, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1526", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVF1-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVF1", "url": "https://www.uniprot.org/uniprotkb/Q9VVF1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 550, "chemical_mass": 64804.0, "gene_names": "Dmel\\CG13724;CG13724;Dmel\\CG13724;Dmel_CG13724", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVF1-1", "start_pos": "348", "end_pos": "348", "site_lbl": "Thr348", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VVF1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VVF1" } ] } ] }, { "uniprot_canonical_ac": "Q9VVF1-1", "start_pos": "350", "end_pos": "350", "site_lbl": "Thr350", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 350, "start_aa": "Thr", "end_pos": 350, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr350", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VVF1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VVF1" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVF5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVF5", "url": "https://www.uniprot.org/uniprotkb/Q9VVF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 302, "chemical_mass": 31788.0, "gene_names": "Dmel\\CG13727;CG13727;Dmel\\CG13727;Dmel_CG13727", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVF5-1", "start_pos": "273", "end_pos": "273", "site_lbl": "Thr273", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 273, "start_aa": "Thr", "end_pos": 273, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr273", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVG2-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVG2", "url": "https://www.uniprot.org/uniprotkb/Q9VVG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 792, "chemical_mass": 86568.0, "gene_names": "Dmel\\CG13731;CG13731;Dmel\\CG13731;Dmel_CG13731", "protein_name": "Proline-rich extensin-like protein EPR1", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "Q9VVG2-1", "start_pos": "268", "end_pos": "268", "site_lbl": "Thr268", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 268, "start_aa": "Thr", "end_pos": 268, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr268", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VVG2-1", "start_pos": "435", "end_pos": "435", "site_lbl": "Thr435", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 435, "start_aa": "Thr", "end_pos": 435, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr435", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "Q9VVG2-1", "start_pos": "73", "end_pos": "73", "site_lbl": "Thr73", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVJ9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1725, "chemical_mass": 195315.0, "gene_names": "Dmel\\CG6052;CG6052;DmCG6052;Dmel_CG6052", "protein_name": "ABC transporter domain-containing protein", "disease": [ { "disease_id": "DOID:11161", "name": "neonatal respiratory failure", "description": "A respiratory failure that is characterized by inadequate gas exchange by the respiratory system in neonates.", "url": "https://disease-ontology.org/term/DOID:11161", "evidence": [ { "id": "11161", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11161" } ], "weight": 0.0 }, { "disease_id": "DOID:11162", "name": "respiratory failure", "description": "A lung disease characterized by inadequate gas exchange by the respiratory system.", "url": "https://disease-ontology.org/term/DOID:11162", "evidence": [ { "id": "11162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11162" } ], "weight": 0.0 }, { "disease_id": "DOID:12120", "name": "pulmonary alveolar proteinosis", "description": "A lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange.", "url": "https://disease-ontology.org/term/DOID:12120", "evidence": [ { "id": "12120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12120" } ], "weight": 0.0 }, { "disease_id": "DOID:12716", "name": "newborn respiratory distress syndrome", "description": "A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.", "url": "https://disease-ontology.org/term/DOID:12716", "evidence": [ { "id": "12716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12716" } ], "weight": 0.0 }, { "disease_id": "DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough.", "url": "https://disease-ontology.org/term/DOID:3082", "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ], "weight": 0.0 }, { "disease_id": "DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.", "url": "https://disease-ontology.org/term/DOID:850", "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" } ], "biological_process": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" } ], "cellular_component": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ9", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVM4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVM4", "url": "https://www.uniprot.org/uniprotkb/Q9VVM4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 579, "chemical_mass": 65054.0, "gene_names": "Dmel\\CG7402;CG7402;Dmel\\CG7402;Dmel_CG7402", "protein_name": "Sulfatase N-terminal domain-containing protein", "disease": [ { "disease_id": "DOID:12800", "name": "mucopolysaccharidosis VI", "description": "A mucopolysaccharidosis characterized by a deficiency of the lysosomal enzyme N-acetylgalactosamine 4-sulfatase.", "url": "https://disease-ontology.org/term/DOID:12800", "evidence": [ { "id": "12800", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12800" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM4", "url": "https://www.uniprot.org/uniprotkb/Q9VVM4" } ], "pmid": "" }, { "name": "N-acetylgalactosamine-4-sulfatase activity", "id": "GO:0003943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003943", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM4", "url": "https://www.uniprot.org/uniprotkb/Q9VVM4" } ], "pmid": "" }, { "name": "sulfuric ester hydrolase activity", "id": "GO:0008484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008484", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM4", "url": "https://www.uniprot.org/uniprotkb/Q9VVM4" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVV0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVV0", "url": "https://www.uniprot.org/uniprotkb/Q9VVV0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 322, "chemical_mass": 36229.0, "gene_names": "Dmel\\CG18223;BcDNA:AT03311;CG18223;Dmel\\CG18223;Dmel_CG18223;SPH200", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV0", "url": "https://www.uniprot.org/uniprotkb/Q9VVV0" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV0", "url": "https://www.uniprot.org/uniprotkb/Q9VVV0" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV0", "url": "https://www.uniprot.org/uniprotkb/Q9VVV0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVW7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 221, "chemical_mass": 25632.0, "gene_names": "CNPYb;CG11577;CNPYb;Dmel\\CG11577;Dmel_CG11577;anon-WO0118547.323", "protein_name": "", "disease": [ { "disease_id": "DOID:0080432", "name": "developmental and epileptic encephalopathy 60", "description": "A developmental and epileptic encephalopathy characterized by onset of infantile spasms, seizures, or myoclonus in the first months of life, hypsarrhythmia on EEG, and severe global developmental delay that has_material_basis_in homozygous or compound heterozygous mutation in the CNPY3 gene on chromosome 6p.", "url": "https://disease-ontology.org/term/DOID:0080432", "evidence": [ { "id": "0080432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080432" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "pmid": "" } ], "biological_process": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "pmid": "" } ], "molecular_function": [ { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW7", "url": "https://www.uniprot.org/uniprotkb/Q9VVW7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVX9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVX9", "url": "https://www.uniprot.org/uniprotkb/Q9VVX9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 289, "chemical_mass": 32032.0, "gene_names": "SPH199;CG14088;Dmel\\CG14088;Dmel_CG14088;SPH199", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX9", "url": "https://www.uniprot.org/uniprotkb/Q9VVX9" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX9", "url": "https://www.uniprot.org/uniprotkb/Q9VVX9" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX9", "url": "https://www.uniprot.org/uniprotkb/Q9VVX9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "R9PY60-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "R9PY60", "url": "https://www.uniprot.org/uniprotkb/R9PY60" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1278, "chemical_mass": 139737.0, "gene_names": "CG14091;CG9600;CG14090;CG14091;CG14092;CG32206;CG9600;Dmel\\CG32206;Dmel_CG32206", "protein_name": "CUB domain-containing protein", "disease": [], "cellular_component": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "R9PY60", "url": "https://www.uniprot.org/uniprotkb/R9PY60" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "R9PY60-1", "start_pos": "258", "end_pos": "258", "site_lbl": "Thr258", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 258, "start_aa": "Thr", "end_pos": 258, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr258", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VVZ4-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVZ4", "url": "https://www.uniprot.org/uniprotkb/Q9VVZ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 162, "chemical_mass": 15946.0, "gene_names": "Dmel\\CG14095;CG14095;Dmel\\CG14095;Dmel_CG14095", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VW52-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 598, "chemical_mass": 67382.0, "gene_names": "Prp3;CG7757;Dmel\\CG7757;Dmel_CG7757;PRPF3;Prp3;dPrp3;prp3", "protein_name": "", "disease": [ { "disease_id": "DOID:0110356", "name": "retinitis pigmentosa 18", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the PRPF3 gene on chromosome 1q21.", "url": "https://disease-ontology.org/term/DOID:0110356", "evidence": [ { "id": "0110356", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110356" } ], "weight": 0.0 }, { "disease_id": "DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss.", "url": "https://disease-ontology.org/term/DOID:10584", "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ], "weight": 0.0 } ], "molecular_function": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" } ], "biological_process": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VW52", "url": "https://www.uniprot.org/uniprotkb/Q9VW52" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VW57-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 460, "chemical_mass": 47724.0, "gene_names": "Grasp65;CG7809;Dmel\\CG7809;Dmel_CG7809;GRASP65;GRASP;Grasp65;dGRASP;dGrasp65;dGrasp;dgrasp", "protein_name": "", "disease": [ { "disease_id": "DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.", "url": "https://disease-ontology.org/term/DOID:9970", "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "apical cortex", "id": "GO:0045179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045179", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi-associated vesicle", "id": "GO:0005798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005798", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of lipid storage", "id": "GO:0010884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010884", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "wing disc morphogenesis", "id": "GO:0007472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007472", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "morphogenesis of follicular epithelium", "id": "GO:0016333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016333", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" }, { "name": "regulation of imaginal disc-derived wing size", "id": "GO:0044719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044719", "evidence": [ { "database": "UniProtKB", "id": "Q9VW57", "url": "https://www.uniprot.org/uniprotkb/Q9VW57" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VW81-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 353, "chemical_mass": 39713.0, "gene_names": "obst-J;CG7348;Dmel\\CG7348;Dmel_CG7348;Obst-J;anon-EST:ParkEST360;obst-J", "protein_name": "", "disease": [], "cellular_component": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "pmid": "" }, { "name": "chitin-based extracellular matrix", "id": "GO:0062129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062129", "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "pmid": "" } ], "molecular_function": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9VW81", "url": "https://www.uniprot.org/uniprotkb/Q9VW81" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VWC5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 158, "chemical_mass": 17569.0, "gene_names": "SkpD;BcDNA:AT18217;CG12700;Dmel\\CG12700;Dmel_CG12700;SkpD;Skp;dskpD;skpD", "protein_name": "", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" } ], "biological_process": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" } ], "molecular_function": [ { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC5", "url": "https://www.uniprot.org/uniprotkb/Q9VWC5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VWG5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWG5", "url": "https://www.uniprot.org/uniprotkb/Q9VWG5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 724, "chemical_mass": 80808.0, "gene_names": "Dmel\\CG14219;CG14219;Dmel\\CG14219;Dmel_CG14219", "protein_name": "Nose resistant-to-fluoxetine protein N-terminal domain-containing protein", "disease": [], "molecular_function": [ { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG5", "url": "https://www.uniprot.org/uniprotkb/Q9VWG5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VWH9-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWH9", "url": "https://www.uniprot.org/uniprotkb/Q9VWH9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 323, "chemical_mass": 39067.0, "gene_names": "Snrnp48;CG12204;Dmel\\CG12204;Dmel_CG12204", "protein_name": "", "disease": [], "cellular_component": [ { "name": "U11/U12 snRNP", "id": "GO:0034693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034693", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH9", "url": "https://www.uniprot.org/uniprotkb/Q9VWH9" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH9", "url": "https://www.uniprot.org/uniprotkb/Q9VWH9" } ], "pmid": "" } ], "biological_process": [ { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "Q9VWH9", "url": "https://www.uniprot.org/uniprotkb/Q9VWH9" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VWP7-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 352, "chemical_mass": 40234.0, "gene_names": "Dmel\\CG7101;CG7101;Dmel\\CG7101;Dmel_CG7101", "protein_name": "C2H2-type domain-containing protein", "disease": [], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" } ], "molecular_function": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q9VWP7", "url": "https://www.uniprot.org/uniprotkb/Q9VWP7" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VWT5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 250, "chemical_mass": 27976.0, "gene_names": "Xrcc2;CG6318;Dm CG6318;Dmel\\CG6318;Dmel_CG6318;Rad51D;XRCC2;Xrcc2;dmRad51D", "protein_name": "", "disease": [ { "disease_id": "DOID:0080874", "name": "primary ovarian insufficiency 17", "description": "A primary ovarian insufficiency that is characterized by early cessation of menses after initial menarche, with small ovaries and uterus and that has_material_basis_in homozygous mutation in the XRCC2 gene on chromosome 7q36.", "url": "https://disease-ontology.org/term/DOID:0080874", "evidence": [ { "id": "0080874", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080874" } ], "weight": 0.0 }, { "disease_id": "DOID:0111085", "name": "Fanconi anemia complementation group U", "description": "A Fanconi anemia that has_material_basis_in homozygous mutation in the XRCC2 gene on chromosome 7q36.", "url": "https://disease-ontology.org/term/DOID:0111085", "evidence": [ { "id": "0111085", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111085" } ], "weight": 0.0 }, { "disease_id": "DOID:0112272", "name": "spermatogenic failure 50", "description": "A spermatogenic failure that is characterized by azoospermia resulting from meiotic arrest at prophase I that has_material_basis_in homozygous or compound heterozygous mutation in the XRCC2 gene on chromosome 7q36.1.", "url": "https://disease-ontology.org/term/DOID:0112272", "evidence": [ { "id": "0112272", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112272" } ], "weight": 0.0 }, { "disease_id": "DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas.", "url": "https://disease-ontology.org/term/DOID:1793", "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "Rad51B-Rad51C-Rad51D-XRCC2 complex", "id": "GO:0033063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033063", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" } ], "biological_process": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" }, { "name": "DNA strand invasion", "id": "GO:0042148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042148", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" } ], "molecular_function": [ { "name": "DNA strand exchange activity", "id": "GO:0000150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000150", "evidence": [ { "database": "UniProtKB", "id": "Q9VWT5", "url": "https://www.uniprot.org/uniprotkb/Q9VWT5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VWY5-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWY5", "url": "https://www.uniprot.org/uniprotkb/Q9VWY5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 417, "chemical_mass": 48592.0, "gene_names": "Dmel\\CG7135;CG7135;Dmel\\CG7135;Dmel_CG7135;Dro32-0", "protein_name": "CHK kinase-like domain-containing protein", "disease": [], "molecular_function": [ { "name": "ecdysteroid 22-kinase activity", "id": "GO:0106389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106389", "evidence": [ { "database": "UniProtKB", "id": "Q9VWY5", "url": "https://www.uniprot.org/uniprotkb/Q9VWY5" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "X2JCF3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 581, "chemical_mass": 65859.0, "gene_names": "RhoGAP16F;CG7122;Dmel\\CG7122;Dmel_CG7122;RhoGAP16F", "protein_name": "", "disease": [], "molecular_function": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" } ], "biological_process": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" }, { "name": "imaginal disc-derived leg morphogenesis", "id": "GO:0007480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007480", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" } ], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "X2JCF3", "url": "https://www.uniprot.org/uniprotkb/X2JCF3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [ { "uniprot_canonical_ac": "X2JCF3-1", "start_pos": "11", "end_pos": "11", "site_lbl": "Thr11", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JCF3-1", "start_pos": "3", "end_pos": "3", "site_lbl": "Thr3", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "X2JCF3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=X2JCF3" } ] } ] }, { "uniprot_canonical_ac": "X2JCF3-1", "start_pos": "451", "end_pos": "451", "site_lbl": "Thr451", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 451, "start_aa": "Thr", "end_pos": 451, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr451", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ] } ] }, { "uniprot_canonical_ac": "X2JCF3-1", "start_pos": "5", "end_pos": "5", "site_lbl": "Thr5", "weight": 0.0, "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 5, "start_aa": "Thr", "end_pos": 5, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr5", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "X2JCF3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=X2JCF3" } ] } ] } ], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VX72-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX72", "url": "https://www.uniprot.org/uniprotkb/Q9VX72" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 170, "chemical_mass": 18839.0, "gene_names": "Dmel\\CG32563;CG32563;CG5095;Dmel\\CG32563;Dmel_CG32563", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VXP8-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 276, "chemical_mass": 29910.0, "gene_names": "Dmel\\CG8952;CG8952;Dmel\\CG8952;Dmel_CG8952;SP52", "protein_name": "Peptidase S1 domain-containing protein", "disease": [], "molecular_function": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" } ], "cellular_component": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" } ], "biological_process": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VXP8", "url": "https://www.uniprot.org/uniprotkb/Q9VXP8" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VXV3-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 2030, "chemical_mass": 227274.0, "gene_names": "shtd;APC1/shtd;APC1;Apc1;CG9198;Dmel\\CG9198;Dmel_CG9198;SHTD;Shtd;shtd", "protein_name": "", "disease": [ { "disease_id": "DOID:2732", "name": "Rothmund-Thomson syndrome", "description": "A skin disease characterized by poikiloderma, congenital bone defects, and an increased risk of osteosarcoma in childhood and skin cancer later in life that has_material_basis_in homozygous or compound heterozygous mutation in the DNA helicase gene RECQL4 on chromosome 8q24.", "url": "https://disease-ontology.org/term/DOID:2732", "evidence": [ { "id": "2732", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2732" } ], "weight": 0.0 } ], "biological_process": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "anaphase-promoting complex-dependent catabolic process", "id": "GO:0031145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031145", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" } ], "molecular_function": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" } ], "cellular_component": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005680", "evidence": [ { "database": "UniProtKB", "id": "Q9VXV3", "url": "https://www.uniprot.org/uniprotkb/Q9VXV3" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VY14-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY14", "url": "https://www.uniprot.org/uniprotkb/Q9VY14" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 201, "chemical_mass": 23633.0, "gene_names": "Dmel\\CG14410;CG14410;Dmel\\CG14410;Dmel_CG14410", "protein_name": "", "disease": [], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VY41-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY41", "url": "https://www.uniprot.org/uniprotkb/Q9VY41" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 154, "chemical_mass": 17937.0, "gene_names": "Dmel\\CG13404;CG13404;Dmel\\CG13404;Dmel_CG13404", "protein_name": "Plasminogen receptor (KT)", "disease": [], "biological_process": [ { "name": "positive regulation of plasminogen activation", "id": "GO:0010756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010756", "evidence": [ { "database": "UniProtKB", "id": "Q9VY41", "url": "https://www.uniprot.org/uniprotkb/Q9VY41" } ], "pmid": "" } ], "cellular_component": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VY41", "url": "https://www.uniprot.org/uniprotkb/Q9VY41" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VY41", "url": "https://www.uniprot.org/uniprotkb/Q9VY41" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VY47-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY47", "url": "https://www.uniprot.org/uniprotkb/Q9VY47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 1280, "chemical_mass": 143567.0, "gene_names": "CG1846;CG1846;CG33248;CG33249;CG42271;Dmel\\CG42271;Dmel_CG42271;FBgn0259166;INPP4A", "protein_name": "phosphatidylinositol-3,4-bisphosphate 4-phosphatase", "disease": [], "cellular_component": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VY47", "url": "https://www.uniprot.org/uniprotkb/Q9VY47" } ], "pmid": "" } ], "molecular_function": [ { "name": "phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity", "id": "GO:0016316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016316", "evidence": [ { "database": "UniProtKB", "id": "Q9VY47", "url": "https://www.uniprot.org/uniprotkb/Q9VY47" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VY62-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY62", "url": "https://www.uniprot.org/uniprotkb/Q9VY62" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 186, "chemical_mass": 19416.0, "gene_names": "Dmel\\CG1368;CG1368;Dmel\\CG1368;Dmel_CG1368", "protein_name": "Cuticle protein 16.5", "disease": [], "molecular_function": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q9VY62", "url": "https://www.uniprot.org/uniprotkb/Q9VY62" } ], "pmid": "" } ], "biological_process": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VY62", "url": "https://www.uniprot.org/uniprotkb/Q9VY62" } ], "pmid": "" } ], "cellular_component": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "Q9VY62", "url": "https://www.uniprot.org/uniprotkb/Q9VY62" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VY83-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 392, "chemical_mass": 44493.0, "gene_names": "Galml2;CG10996;Dmel\\CG10996;Dmel_CG10996", "protein_name": "Galactose mutarotase", "disease": [ { "disease_id": "DOID:0060969", "name": "galactosemia 4", "description": "A galactosemia characterized by persistent congenital galactosemia due to deficiency of the enzyme galactose mutarotase that has_material_basis_in homozygous or compound heterozygous mutation in the GALM gene on chromosome 2p22.", "url": "https://disease-ontology.org/term/DOID:0060969", "evidence": [ { "id": "0060969", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060969" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "pmid": "" } ], "molecular_function": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "pmid": "" } ], "biological_process": [ { "name": "galactose metabolic process", "id": "GO:0006012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006012", "evidence": [ { "database": "UniProtKB", "id": "Q9VY83", "url": "https://www.uniprot.org/uniprotkb/Q9VY83" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" }, { "uniprot_canonical_ac": "Q9VYE0-1", "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "length": 377, "chemical_mass": 41301.0, "gene_names": "dmrt11E;CG15749;Dmel\\CG15749;Dmel_CG15749;Dmrt11E;dmrt11E;dmrt11", "protein_name": "", "disease": [ { "disease_id": "DOID:14227", "name": "azoospermia", "description": "A male infertility disease characterized by the absence of any measurable level of sperm in semen.", "url": "https://disease-ontology.org/term/DOID:14227", "evidence": [ { "id": "14227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14227" } ], "weight": 0.0 } ], "cellular_component": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" } ], "biological_process": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "sex differentiation", "id": "GO:0007548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007548", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" } ], "molecular_function": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "Q9VYE0", "url": "https://www.uniprot.org/uniprotkb/Q9VYE0" } ], "pmid": "" } ], "binding_glycans": [], "biomarkers": [], "sites": [], "record_id": "batch.fruitfly.8" } ]