{
    "bcoid": "GLY_001728",
    "title": "Human Gene Groups",
    "description": "The Human Gene Groups dataset contains Homo sapiens [taxid:9606] UniProtKB accessions that have been ...",
    "filename_list": "human_protein_gene_groups.csv",
    "filename": "human_protein_gene_groups.csv",
    "filetype": "csv",
    "categories": {
        "species": [
            "Homo sapiens"
        ],
        "molecule": [
            "Protein"
        ],
        "tag": [
            "Gene groups"
        ],
        "file_type": [
            "csv"
        ],
        "status": [
            "Reviewed"
        ],
        "scope": [
            "internal"
        ],
        "file_category": [
            "others"
        ]
    },
    "minitable": {
        "content": [
            [
                "A0A075B6H7-1...",
                "Immunoglobin..."
            ],
            [
                "A0A075B6H8-1...",
                "Immunoglobin..."
            ]
        ],
        "headers": [
            "uniprotkb_ca...",
            "gene_group..."
        ],
        "colwidth": [
            "40%",
            "20%"
        ]
    },
    "sampledata": {
        "type": "table",
        "data": [
            [
                {
                    "type": "string",
                    "label": "uniprotkb_canonical_ac"
                },
                {
                    "type": "string",
                    "label": "gene_group"
                }
            ],
            [
                "A0A075B6H7-1",
                "Immunoglobin"
            ],
            [
                "A0A075B6H8-1",
                "Immunoglobin"
            ]
        ]
    },
    "readme": "Name\n   - Human Gene Groups\n\nVersion\n   - v-2.12.1\n\nModified on\n   - 2026-08-24T10:14:29.269Z\n\nCreated by\n   - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Urnisha Bhuiyan [sbhuiyan28@email.gwu.edu], Kate Warner [k.warner1@gwu.edu]\n\nAuthors\n   - \n\nChecksum\n   - \n\nUsability Domain\n   - The Human Gene Groups dataset contains Homo sapiens [taxid:9606] UniProtKB accessions that have been identified as potential proteins of interest for our users. Proteins are categorized into gene groups to enable identification and the 'Protein of Interest' filters on the protein list page of the GlyGen portal. The subcategories include all proteins in GlyGen defined as 'Glycosylhydrolases', 'Glycosyltransferases', or 'Glycan-modifying enzymes' by CAZy, and/or its enzyme classification in UniProtKB. The parent category 'GlycoGenes' encompasses the subcategories 'Glycosylhydrolases', 'Glycosyltransferases', and 'Glycan-modifying enzymes'. The 'GlycoGenes' category also contain all glycan-related genes from the publication from UGA [PMID:18411279] which include glycosylhydrolases, glycosyltransferases, carbohydrate-binding modules and carbohydrate esterases, as defined by CAZy, Lectins (following Kurt Drickamer\u2019s groupings), then several other glycan-related genes like glycolipid-related, GAG-related, etc. There is also a gene group category for reviewed SwissProt proteins identified as immunoglobins in UniProtKB database by the keyword immunoglobin (Immunoglobulin [KW-1280]). If you use this dataset, please provide proper attribution to UniProtKB, GlyGen, CAZy, and cite PMID:18411279.\n\nDescription Domain\n   Keywords\n   - Gene groups\n   - GlycoGenes\n   - Glycosyltransferases\n   - Glycosylhydrolases\n   - Glycan-modifying enzymes\n\n   Pipeline Steps\n   - Step-1: The script extracts proteins of interest from the input datasets, maps them to the canonical UniProtKB canonical protein, and adds the gene_group categories of each protein. Added gene groups include the parent category GlycoGene, which contains the subcategories Glycosyltransferases, Glycosylhydrolases, Glycan-modifying enzymes, and all genes in the publication input file. For the publication input file, the script maps the gene ids and gene names from the source file to UniProtKB canonical accession.\n\nExecution Domain\n   Scripts   - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n   Software Prerequisites\n      Name: Python\n      Version: 2.7.5\n      URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n   Input Subdomain\n      Name: human_protein_gene_groups.csv\n      URI: https:/data.glygen.org/ln2downloads/gene_groups/2026_08_19/human_protein_gene_groups.csv\n   Output Subdomain\n      Name: human_protein_gene_groups.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.12.1/reviewed/human_protein_gene_groups.csv\n      Name: human_protein_gene_groups.stat.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.12.1/reviewed/human_protein_gene_groups.stat.csv\n\nFields\n      Name: \"uniprotkb_canonical_ac\"\"\n     Description: \"\"\n      Unique Values: \"1056\"",
    "downloadurl": "/ln2data/releases/data/v-2.12.1/reviewed/human_protein_gene_groups.csv"
}