{
    "disease_id": "DOID:0112169",
    "recommended_name": {
        "id": "DOID:0112169",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0112169",
        "name": "Noonan syndrome 11",
        "description": "A Noonan syndrome characterized by clinical characteristics of Noonan syndrome, varying impairment of intellectual development, and cardiac hypertrophy that has_material_basis_in heterozygous mutation in the MRAS gene on chromosome 3q22.3."
    },
    "synonyms": [
        {
            "id": "DOID:0112169",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0112169",
            "name": "NS11",
            "description": ""
        },
        {
            "id": "MONDO:0032786",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032786",
            "name": "Noonan syndrome 11",
            "description": ""
        },
        {
            "id": "MONDO:0032786",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032786",
            "name": "NS11",
            "description": ""
        },
        {
            "id": "MIM:618499",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/618499",
            "name": "Noonan syndrome 11",
            "description": "Noonan syndrome 11"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0112169"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0112169",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0112169",
            "categories": []
        },
        {
            "id": "MONDO:0032786",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032786",
            "categories": []
        },
        {
            "id": "MIM:618499",
            "database": "MIM",
            "url": "https://www.omim.org/entry/618499",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A286Y9A7-1",
            "uniprot_ac": "A0A286Y9A7",
            "uniprot_id": "A0A286Y9A7_DANRE",
            "refseq_ac": "XP_003201047",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ras-related protein M-Ras",
                    "type": "synonym"
                },
                {
                    "name": "ras-related protein M-Ras",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "mrasb",
                    "type": "recommended"
                },
                {
                    "name": "mrasb",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A286Y9A7-1",
            "evidence": [
                {
                    "id": "0112169",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0112169"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O08989-1",
            "uniprot_ac": "O08989",
            "uniprot_id": "RASM_MOUSE",
            "refseq_ac": "NP_032650",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ras-related protein M-Ras",
                    "type": "recommended"
                },
                {
                    "name": "3.6.5.2",
                    "type": "synonym"
                },
                {
                    "name": "Muscle and microspikes Ras",
                    "type": "synonym"
                },
                {
                    "name": "Ras-related protein R-Ras3",
                    "type": "synonym"
                },
                {
                    "name": "X-Ras",
                    "type": "synonym"
                },
                {
                    "name": "ras-related protein M-Ras",
                    "type": "synonym"
                },
                {
                    "name": "ras-related protein R-Ras3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Mras",
                    "type": "recommended"
                },
                {
                    "name": "2900078C09Rik",
                    "type": "synonym"
                },
                {
                    "name": "Mras",
                    "type": "synonym"
                },
                {
                    "name": "Xras",
                    "type": "synonym"
                }
            ],
            "record_id": "O08989-1",
            "evidence": [
                {
                    "id": "0112169",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0112169"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O14807-1",
            "uniprot_ac": "O14807",
            "uniprot_id": "RASM_HUMAN",
            "refseq_ac": "NP_001078518",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ras-related protein M-Ras",
                    "type": "recommended"
                },
                {
                    "name": "3.6.5.2",
                    "type": "synonym"
                },
                {
                    "name": "Ras-related protein R-Ras3",
                    "type": "synonym"
                },
                {
                    "name": "muscle and microspikes RAS",
                    "type": "synonym"
                },
                {
                    "name": "ras-related protein M-Ras isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "ras-related protein M-Ras",
                    "type": "synonym"
                },
                {
                    "name": "ras-related protein R-Ras3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "MRAS",
                    "type": "recommended"
                },
                {
                    "name": "M-RAs",
                    "type": "synonym"
                },
                {
                    "name": "MRAS",
                    "type": "synonym"
                },
                {
                    "name": "NS11",
                    "type": "synonym"
                },
                {
                    "name": "R-RAS3",
                    "type": "synonym"
                },
                {
                    "name": "RRAS3",
                    "type": "synonym"
                }
            ],
            "record_id": "O14807-1",
            "evidence": [
                {
                    "id": "618499",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/618499"
                },
                {
                    "id": "0112169",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0112169"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P97538-1",
            "uniprot_ac": "P97538",
            "uniprot_id": "RASM_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ras-related protein M-Ras",
                    "type": "recommended"
                },
                {
                    "name": "3.6.5.2",
                    "type": "synonym"
                },
                {
                    "name": "Ras-related protein R-Ras3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Mras",
                    "type": "recommended"
                },
                {
                    "name": "Rras3",
                    "type": "synonym"
                }
            ],
            "record_id": "P97538-1",
            "evidence": [
                {
                    "id": "0112169",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0112169"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0112169"
}