{
    "disease_id": "DOID:0111287",
    "recommended_name": {
        "id": "DOID:0111287",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0111287",
        "name": "psoriasis 13",
        "description": "A psoriasis that has_material_basis_in variation in the TRAF3IP2 gene on chromosome 6q21."
    },
    "synonyms": [
        {
            "id": "DOID:0111287",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111287",
            "name": "PSORS13",
            "description": ""
        },
        {
            "id": "MONDO:0013554",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013554",
            "name": "psoriasis 13, susceptibility to",
            "description": "Any psoriasis in which the cause of the disease is a mutation in the TRAF3IP2 gene."
        },
        {
            "id": "MONDO:0013554",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013554",
            "name": "TRAF3IP2 psoriasis",
            "description": ""
        },
        {
            "id": "MONDO:0013554",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013554",
            "name": "psoriasis 13, susceptibility to",
            "description": ""
        },
        {
            "id": "MONDO:0013554",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013554",
            "name": "psoriasis caused by mutation in TRAF3IP2",
            "description": ""
        },
        {
            "id": "MONDO:0013554",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013554",
            "name": "psoriasis susceptibility 13",
            "description": ""
        },
        {
            "id": "MONDO:0013554",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013554",
            "name": "PSORS13",
            "description": ""
        },
        {
            "id": "MIM:614070",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/614070",
            "name": "Psoriasis 13",
            "description": "Psoriasis 13"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0111287"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0111287",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111287",
            "categories": []
        },
        {
            "id": "MONDO:0013554",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013554",
            "categories": []
        },
        {
            "id": "MIM:614070",
            "database": "MIM",
            "url": "https://www.omim.org/entry/614070",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0AC58GU74-1",
            "uniprot_ac": "A0AC58GU74",
            "uniprot_id": "A0AC58GU74_DANRE",
            "refseq_ac": "XP_073773279",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "E3 ubiquitin ligase TRAF3IP2",
                    "type": "recommended"
                },
                {
                    "name": "2.3.2.27",
                    "type": "synonym"
                },
                {
                    "name": "Adapter protein CIKS",
                    "type": "synonym"
                },
                {
                    "name": "Connection to IKK and SAPK/JNK",
                    "type": "synonym"
                },
                {
                    "name": "E3 ubiquitin-protein ligase CIKS",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear factor NF-kappa-B activator 1",
                    "type": "synonym"
                },
                {
                    "name": "TRAF3-interacting protein 2",
                    "type": "synonym"
                },
                {
                    "name": "uncharacterized protein traf3ip2b isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "traf3ip2b",
                    "type": "recommended"
                },
                {
                    "name": "traf3ip2b",
                    "type": "synonym"
                }
            ],
            "record_id": "A0AC58GU74-1",
            "evidence": [
                {
                    "id": "0111287",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111287"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q8N7N6-1",
            "uniprot_ac": "Q8N7N6",
            "uniprot_id": "CIKS_MOUSE",
            "refseq_ac": "NP_598761",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "E3 ubiquitin ligase TRAF3IP2",
                    "type": "recommended"
                },
                {
                    "name": "2.3.2.27",
                    "type": "synonym"
                },
                {
                    "name": "ACT1",
                    "type": "synonym"
                },
                {
                    "name": "Adapter protein CIKS",
                    "type": "synonym"
                },
                {
                    "name": "Connection to IKK and SAPK/JNK",
                    "type": "synonym"
                },
                {
                    "name": "E3 ubiquitin ligase TRAF3IP2",
                    "type": "synonym"
                },
                {
                    "name": "E3 ubiquitin-protein ligase CIKS",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear factor NF-kappa-B activator 1",
                    "type": "synonym"
                },
                {
                    "name": "TRAF3-interacting protein 2",
                    "type": "synonym"
                },
                {
                    "name": "adapter protein CIKS",
                    "type": "synonym"
                },
                {
                    "name": "connection to IKK and SAPK/JNK",
                    "type": "synonym"
                },
                {
                    "name": "nuclear factor NF-kappa-B activator 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Traf3ip2",
                    "type": "recommended"
                },
                {
                    "name": "Act1",
                    "type": "synonym"
                },
                {
                    "name": "CIKS",
                    "type": "synonym"
                },
                {
                    "name": "Traf3ip2",
                    "type": "synonym"
                }
            ],
            "record_id": "Q8N7N6-1",
            "evidence": [
                {
                    "id": "0111287",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111287"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O43734-1",
            "uniprot_ac": "O43734",
            "uniprot_id": "CIKS_HUMAN",
            "refseq_ac": "NP_001157753",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "E3 ubiquitin ligase TRAF3IP2",
                    "type": "recommended"
                },
                {
                    "name": "2.3.2.27",
                    "type": "synonym"
                },
                {
                    "name": "ACT1",
                    "type": "synonym"
                },
                {
                    "name": "Adapter protein CIKS",
                    "type": "synonym"
                },
                {
                    "name": "Connection to IKK and SAPK/JNK",
                    "type": "synonym"
                },
                {
                    "name": "E3 ubiquitin ligase TRAF3IP2 isoform 3",
                    "type": "synonym"
                },
                {
                    "name": "E3 ubiquitin ligase TRAF3IP2",
                    "type": "synonym"
                },
                {
                    "name": "E3 ubiquitin-protein ligase CIKS",
                    "type": "synonym"
                },
                {
                    "name": "NFkB-activating protein ACT1",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear factor NF-kappa-B activator 1",
                    "type": "synonym"
                },
                {
                    "name": "TRAF3-interacting protein 2",
                    "type": "synonym"
                },
                {
                    "name": "adapter protein CIKS",
                    "type": "synonym"
                },
                {
                    "name": "connection to IKK and SAPK/JNK",
                    "type": "synonym"
                },
                {
                    "name": "nuclear factor NF-kappa-B activator 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "TRAF3IP2",
                    "type": "recommended"
                },
                {
                    "name": "ACT1",
                    "type": "synonym"
                },
                {
                    "name": "C6orf2",
                    "type": "synonym"
                },
                {
                    "name": "C6orf4",
                    "type": "synonym"
                },
                {
                    "name": "C6orf5",
                    "type": "synonym"
                },
                {
                    "name": "C6orf6",
                    "type": "synonym"
                },
                {
                    "name": "CANDF8",
                    "type": "synonym"
                },
                {
                    "name": "CIKS",
                    "type": "synonym"
                },
                {
                    "name": "PSORS13",
                    "type": "synonym"
                },
                {
                    "name": "TRAF3IP2",
                    "type": "synonym"
                }
            ],
            "record_id": "O43734-1",
            "evidence": [
                {
                    "id": "614070",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/614070"
                },
                {
                    "id": "0111287",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111287"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I5ZS21-1",
            "uniprot_ac": "A0A8I5ZS21",
            "uniprot_id": "A0A8I5ZS21_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "E3 ubiquitin ligase TRAF3IP2",
                    "type": "recommended"
                },
                {
                    "name": "2.3.2.27",
                    "type": "synonym"
                },
                {
                    "name": "Adapter protein CIKS",
                    "type": "synonym"
                },
                {
                    "name": "Connection to IKK and SAPK/JNK",
                    "type": "synonym"
                },
                {
                    "name": "E3 ubiquitin-protein ligase CIKS",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear factor NF-kappa-B activator 1",
                    "type": "synonym"
                },
                {
                    "name": "TRAF3-interacting protein 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Traf3ip2",
                    "type": "recommended"
                }
            ],
            "record_id": "A0A8I5ZS21-1",
            "evidence": [
                {
                    "id": "0111287",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111287"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0111287"
}