{
    "disease_id": "DOID:0111275",
    "recommended_name": {
        "id": "DOID:0111275",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0111275",
        "name": "speech-language disorder-1",
        "description": "A speech disorder characterized by severe orofacial dyspraxia resulting in largely incomprehensible speech that has_material_basis_in heterozygous mutation in FOXP2 on 7q31.1."
    },
    "synonyms": [
        {
            "id": "DOID:0111275",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111275",
            "name": "CAS",
            "description": ""
        },
        {
            "id": "DOID:0111275",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111275",
            "name": "speech and language disorder with orofacial dyspraxia",
            "description": ""
        },
        {
            "id": "DOID:0111275",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111275",
            "name": "articulatory apraxia",
            "description": ""
        },
        {
            "id": "DOID:0111275",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111275",
            "name": "childhood apraxia of speech",
            "description": ""
        },
        {
            "id": "DOID:0111275",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111275",
            "name": "developmental apraxia of speech",
            "description": ""
        },
        {
            "id": "DOID:0111275",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111275",
            "name": "developmental verbal dyspraxia",
            "description": ""
        },
        {
            "id": "DOID:0111275",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111275",
            "name": "speech-language disorder type 1",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "childhood apraxia of speech",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "CAS",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
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            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "childhood apraxia of speech",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
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            "name": "developmental verbal dyspraxia",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "speech and language disorder with orofacial dyspraxia",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "speech-language disorder type 1",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "SPCH1",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "articulatory apraxia",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "das",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "developmental apraxia of speech",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "developmental verbal apraxia",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "speech-language disorder 1",
            "description": ""
        },
        {
            "id": "MONDO:0011184",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "name": "speech-language disorder-1",
            "description": ""
        },
        {
            "id": "MIM:602081",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/602081",
            "name": "Speech-language disorder 1",
            "description": "Speech-language disorder 1"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0111275"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0111275",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111275",
            "categories": []
        },
        {
            "id": "MONDO:0011184",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011184",
            "categories": []
        },
        {
            "id": "MIM:602081",
            "database": "MIM",
            "url": "https://www.omim.org/entry/602081",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0AB32TLD3-1",
            "uniprot_ac": "A0AB32TLD3",
            "uniprot_id": "A0AB32TLD3_DANRE",
            "refseq_ac": "XP_068075726",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein P2 isoform X1",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P2 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "foxp2",
                    "type": "recommended"
                },
                {
                    "name": "foxp2",
                    "type": "synonym"
                }
            ],
            "record_id": "A0AB32TLD3-1",
            "evidence": [
                {
                    "id": "0111275",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111275"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P58463-1",
            "uniprot_ac": "P58463",
            "uniprot_id": "FOXP2_MOUSE",
            "refseq_ac": "NP_001273536",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein P2",
                    "type": "recommended"
                },
                {
                    "name": "forkhead box protein P2 isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Foxp2",
                    "type": "recommended"
                },
                {
                    "name": "2810043D05Rik",
                    "type": "synonym"
                },
                {
                    "name": "CAG-16",
                    "type": "synonym"
                },
                {
                    "name": "D0Kist7",
                    "type": "synonym"
                },
                {
                    "name": "Foxp2",
                    "type": "synonym"
                }
            ],
            "record_id": "P58463-1",
            "evidence": [
                {
                    "id": "0111275",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111275"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O15409-1",
            "uniprot_ac": "O15409",
            "uniprot_id": "FOXP2_HUMAN",
            "refseq_ac": "NP_001166237",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein P2",
                    "type": "recommended"
                },
                {
                    "name": "CAG repeat protein 44",
                    "type": "synonym"
                },
                {
                    "name": "Trinucleotide repeat-containing gene 10 protein",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P2 isoform V",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P2",
                    "type": "synonym"
                },
                {
                    "name": "forkhead/winged-helix transcription factor",
                    "type": "synonym"
                },
                {
                    "name": "trinucleotide repeat containing 10",
                    "type": "synonym"
                },
                {
                    "name": "trinucleotide repeat-containing gene 10 protein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FOXP2",
                    "type": "recommended"
                },
                {
                    "name": "CAGH44",
                    "type": "synonym"
                },
                {
                    "name": "FOXP2",
                    "type": "synonym"
                },
                {
                    "name": "SPCH1",
                    "type": "synonym"
                },
                {
                    "name": "TNRC10",
                    "type": "synonym"
                }
            ],
            "record_id": "O15409-1",
            "evidence": [
                {
                    "id": "602081",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/602081"
                },
                {
                    "id": "0111275",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111275"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P0CF24-1",
            "uniprot_ac": "P0CF24",
            "uniprot_id": "FOXP2_RAT",
            "refseq_ac": "NP_001258033",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein P2",
                    "type": "recommended"
                },
                {
                    "name": "Forkhead box protein P2",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P2 isoform 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Foxp2",
                    "type": "recommended"
                },
                {
                    "name": "Foxp2",
                    "type": "synonym"
                },
                {
                    "name": "RGD1559697",
                    "type": "synonym"
                }
            ],
            "record_id": "P0CF24-1",
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                {
                    "id": "0111275",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111275"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0B4K6N2-1",
            "uniprot_ac": "A0A0B4K6N2",
            "uniprot_id": "A0A0B4K6N2_DROME",
            "refseq_ac": "NP_001247011",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "CG43067-PC",
                    "type": "synonym"
                },
                {
                    "name": "Forkhead box P, isoform C",
                    "type": "synonym"
                },
                {
                    "name": "FoxP-PC",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box P, isoform C",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box P",
                    "type": "synonym"
                },
                {
                    "name": "forkhead domain 85E",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FoxP",
                    "type": "recommended"
                },
                {
                    "name": "CG16899",
                    "type": "synonym"
                },
                {
                    "name": "CG32937",
                    "type": "synonym"
                },
                {
                    "name": "CG43067",
                    "type": "synonym"
                },
                {
                    "name": "DmFoxP",
                    "type": "synonym"
                },
                {
                    "name": "Dmcg16899",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG43067",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG43067",
                    "type": "synonym"
                },
                {
                    "name": "FoxP",
                    "type": "synonym"
                },
                {
                    "name": "dFoxP",
                    "type": "synonym"
                },
                {
                    "name": "fd85E",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0B4K6N2-1",
            "evidence": [
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                    "id": "0111275",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111275"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0111275"
}