{
    "disease_id": "DOID:0110890",
    "recommended_name": {
        "id": "DOID:0110890",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0110890",
        "name": "inflammatory bowel disease 19",
        "description": "An inflammatory bowel disease that has_material_basis_in variation in the chromosome region 5q33.1."
    },
    "synonyms": [
        {
            "id": "DOID:0110890",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110890",
            "name": "IBD19",
            "description": ""
        },
        {
            "id": "DOID:0110890",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110890",
            "name": "inflammatory bowel disease (Crohn disease) 19",
            "description": ""
        },
        {
            "id": "MONDO:0012845",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012845",
            "name": "inflammatory bowel disease 19",
            "description": "Any inflammatory bowel disease in which the cause of the disease is a mutation in the IRGM gene."
        },
        {
            "id": "MONDO:0012845",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012845",
            "name": "IBD19",
            "description": ""
        },
        {
            "id": "MONDO:0012845",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012845",
            "name": "IRGM inflammatory bowel disease",
            "description": ""
        },
        {
            "id": "MONDO:0012845",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012845",
            "name": "inflammatory bowel disease (Crohn disease) 19",
            "description": ""
        },
        {
            "id": "MONDO:0012845",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012845",
            "name": "inflammatory bowel disease 19",
            "description": ""
        },
        {
            "id": "MONDO:0012845",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012845",
            "name": "inflammatory bowel disease caused by mutation in IRGM",
            "description": ""
        },
        {
            "id": "MONDO:0012845",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012845",
            "name": "inflammatory bowel disease type 19",
            "description": ""
        },
        {
            "id": "MIM:612278",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/612278",
            "name": "Inflammatory bowel disease 19",
            "description": "Inflammatory bowel disease 19"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0110890"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0110890",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110890",
            "categories": []
        },
        {
            "id": "MONDO:0012845",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012845",
            "categories": []
        },
        {
            "id": "MIM:612278",
            "database": "MIM",
            "url": "https://www.omim.org/entry/612278",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q60766-1",
            "uniprot_ac": "Q60766",
            "uniprot_id": "IRGM1_MOUSE",
            "refseq_ac": "NP_032352",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Immunity-related GTPase family M protein 1",
                    "type": "recommended"
                },
                {
                    "name": "3.6.5.-",
                    "type": "synonym"
                },
                {
                    "name": "Interferon-inducible GTPase 3",
                    "type": "synonym"
                },
                {
                    "name": "Interferon-inducible protein 1",
                    "type": "synonym"
                },
                {
                    "name": "LPS-stimulated RAW 264.7 macrophage protein 47",
                    "type": "synonym"
                },
                {
                    "name": "LRG-47",
                    "type": "synonym"
                },
                {
                    "name": "immunity related GTPase m1",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family M protein 1 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family M protein 1",
                    "type": "synonym"
                },
                {
                    "name": "interferon-gamma-inducible GTPase Ifggd3 protein",
                    "type": "synonym"
                },
                {
                    "name": "interferon-inducible protein 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Irgm1",
                    "type": "recommended"
                },
                {
                    "name": "Ifggd3",
                    "type": "synonym"
                },
                {
                    "name": "Ifi1",
                    "type": "synonym"
                },
                {
                    "name": "Iigp3",
                    "type": "synonym"
                },
                {
                    "name": "Iipg3",
                    "type": "synonym"
                },
                {
                    "name": "Irgm1",
                    "type": "synonym"
                },
                {
                    "name": "Irgm",
                    "type": "synonym"
                }
            ],
            "record_id": "Q60766-1",
            "evidence": [
                {
                    "id": "0110890",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110890"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A140LIF8-1",
            "uniprot_ac": "A0A140LIF8",
            "uniprot_id": "IRGM2_MOUSE",
            "refseq_ac": "NP_062313",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Immunity-related GTPase family M protein 2",
                    "type": "recommended"
                },
                {
                    "name": "3.6.5.-",
                    "type": "synonym"
                },
                {
                    "name": "Interferon-inducible GTPase 2",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family M protein 2 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family M protein 2",
                    "type": "synonym"
                },
                {
                    "name": "interferon inducible GTPase 2",
                    "type": "synonym"
                },
                {
                    "name": "interferon-g induced GTPase",
                    "type": "synonym"
                },
                {
                    "name": "interferon-gamma-inducible GTPase Ifggd2 protein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Irgm2",
                    "type": "recommended"
                },
                {
                    "name": "GTPI",
                    "type": "synonym"
                },
                {
                    "name": "Ifggd2",
                    "type": "synonym"
                },
                {
                    "name": "Iigp2",
                    "type": "synonym"
                },
                {
                    "name": "Irgm2",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A140LIF8-1",
            "evidence": [
                {
                    "id": "0110890",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110890"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9DCE9-1",
            "uniprot_ac": "Q9DCE9",
            "uniprot_id": "IRGM3_MOUSE",
            "refseq_ac": "NP_061208",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Immunity-related GTPase family M protein 3",
                    "type": "recommended"
                },
                {
                    "name": "3.6.5.-",
                    "type": "synonym"
                },
                {
                    "name": "Interferon gamma-induced GTPase",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family M protein 3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Igtp",
                    "type": "recommended"
                },
                {
                    "name": "Igtp",
                    "type": "synonym"
                },
                {
                    "name": "Irgm3",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9DCE9-1",
            "evidence": [
                {
                    "id": "0110890",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110890"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A1A4Y4-1",
            "uniprot_ac": "A1A4Y4",
            "uniprot_id": "IRGM_HUMAN",
            "refseq_ac": "NP_001139277",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Immunity-related GTPase family M protein",
                    "type": "recommended"
                },
                {
                    "name": "3.6.5.-",
                    "type": "synonym"
                },
                {
                    "name": "Immunity-related GTPase family M protein 1",
                    "type": "synonym"
                },
                {
                    "name": "Interferon-inducible protein 1",
                    "type": "synonym"
                },
                {
                    "name": "LPS-stimulated RAW 264.7 macrophage protein 47 homolog",
                    "type": "synonym"
                },
                {
                    "name": "LRG-47-like protein",
                    "type": "synonym"
                },
                {
                    "name": "LRG-47",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family M protein isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family M protein",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family, M1",
                    "type": "synonym"
                },
                {
                    "name": "interferon-inducible protein 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "IRGM",
                    "type": "recommended"
                },
                {
                    "name": "IBD19",
                    "type": "synonym"
                },
                {
                    "name": "IFI1",
                    "type": "synonym"
                },
                {
                    "name": "IRGM1",
                    "type": "synonym"
                },
                {
                    "name": "IRGM",
                    "type": "synonym"
                },
                {
                    "name": "LRG-47",
                    "type": "synonym"
                },
                {
                    "name": "LRG47",
                    "type": "synonym"
                }
            ],
            "record_id": "A1A4Y4-1",
            "evidence": [
                {
                    "id": "612278",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/612278"
                },
                {
                    "id": "0110890",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110890"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I5ZSB0-1",
            "uniprot_ac": "A0A8I5ZSB0",
            "uniprot_id": "A0A8I5ZSB0_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Interferon gamma induced GTPase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Igtpl1",
                    "type": "recommended"
                },
                {
                    "name": "Igtp",
                    "type": "recommended"
                }
            ],
            "record_id": "A0A8I5ZSB0-1",
            "evidence": [
                {
                    "id": "0110890",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110890"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q6AYC2-1",
            "uniprot_ac": "Q6AYC2",
            "uniprot_id": "IRGM_RAT",
            "refseq_ac": "NP_001012007",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Immunity-related GTPase family M protein",
                    "type": "recommended"
                },
                {
                    "name": "3.6.5.-",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family M protein",
                    "type": "synonym"
                },
                {
                    "name": "immunity-related GTPase family, M",
                    "type": "synonym"
                },
                {
                    "name": "interferon inducible protein 1",
                    "type": "synonym"
                },
                {
                    "name": "interferon-gamma-inducible GTPase Ifggd3 protein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Irgm",
                    "type": "recommended"
                },
                {
                    "name": "Ifggd3",
                    "type": "synonym"
                },
                {
                    "name": "Ifi1",
                    "type": "synonym"
                },
                {
                    "name": "Irgm",
                    "type": "synonym"
                }
            ],
            "record_id": "Q6AYC2-1",
            "evidence": [
                {
                    "id": "0110890",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110890"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0110890"
}