{
    "disease_id": "DOID:0110235",
    "recommended_name": {
        "id": "DOID:0110235",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0110235",
        "name": "cataract 2 multiple types",
        "description": "A cataract that has_material_basis_in heterozygous mutation in the CRYGC gene on chromosome 2q33."
    },
    "synonyms": [
        {
            "id": "DOID:0110235",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110235",
            "name": "CTRCT2",
            "description": ""
        },
        {
            "id": "DOID:0110235",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110235",
            "name": "cataract 2 multiple types with or without microcornea",
            "description": ""
        },
        {
            "id": "MONDO:0100436",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0100436",
            "name": "cataract 2, multiple types",
            "description": "Any cataract in which the cause of the disease is a mutation in the CRYGC gene."
        },
        {
            "id": "MONDO:0100436",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0100436",
            "name": "CTRCT2",
            "description": ""
        },
        {
            "id": "MONDO:0100436",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0100436",
            "name": "cataract 2, multiple types, with or without microcornea",
            "description": ""
        },
        {
            "id": "MONDO:0100436",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0100436",
            "name": "cataract, Coppock-like",
            "description": ""
        },
        {
            "id": "MIM:604307",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/604307",
            "name": "Cataract 2, multiple types",
            "description": "Cataract 2, multiple types"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0110235"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0110235",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110235",
            "categories": []
        },
        {
            "id": "MONDO:0100436",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0100436",
            "categories": []
        },
        {
            "id": "MIM:604307",
            "database": "MIM",
            "url": "https://www.omim.org/entry/604307",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8N7TEM3-1",
            "uniprot_ac": "A0A8N7TEM3",
            "uniprot_id": "A0A8N7TEM3_DANRE",
            "refseq_ac": "XP_698092",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Gamma-crystallin M2",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin M2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "crygm2e",
                    "type": "recommended"
                },
                {
                    "name": "crygm2e",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8N7TEM3-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P04342-1",
            "uniprot_ac": "P04342",
            "uniprot_id": "CRGD_MOUSE",
            "refseq_ac": "NP_031802",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Gamma-crystallin D",
                    "type": "recommended"
                },
                {
                    "name": "Gamma-D-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-crystallin 1",
                    "type": "synonym"
                },
                {
                    "name": "gamma-D-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin 1",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin D",
                    "type": "synonym"
                },
                {
                    "name": "lens opacity 12",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Crygd",
                    "type": "recommended"
                },
                {
                    "name": "Aey4",
                    "type": "synonym"
                },
                {
                    "name": "Cryg-1",
                    "type": "synonym"
                },
                {
                    "name": "Crygd",
                    "type": "synonym"
                },
                {
                    "name": "DGcry-1",
                    "type": "synonym"
                },
                {
                    "name": "Lop12",
                    "type": "synonym"
                }
            ],
            "record_id": "P04342-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q61597-1",
            "uniprot_ac": "Q61597",
            "uniprot_id": "CRGC_MOUSE",
            "refseq_ac": "NP_031801",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Gamma-crystallin C",
                    "type": "recommended"
                },
                {
                    "name": "Gamma-C-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "gamma-C-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin C isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin C",
                    "type": "synonym"
                },
                {
                    "name": "gammaC-crystallin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Crygc",
                    "type": "recommended"
                },
                {
                    "name": "Cryg-5",
                    "type": "synonym"
                },
                {
                    "name": "Crygc",
                    "type": "synonym"
                },
                {
                    "name": "Gammab-cry",
                    "type": "synonym"
                }
            ],
            "record_id": "Q61597-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P07315-1",
            "uniprot_ac": "P07315",
            "uniprot_id": "CRGC_HUMAN",
            "refseq_ac": "NP_066269",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Gamma-crystallin C",
                    "type": "recommended"
                },
                {
                    "name": "Gamma-C-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-crystallin 2-1",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-crystallin 3",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin 2-1",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin 3",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin C",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CRYGC",
                    "type": "recommended"
                },
                {
                    "name": "CCL",
                    "type": "synonym"
                },
                {
                    "name": "CRYG3",
                    "type": "synonym"
                },
                {
                    "name": "CRYGC",
                    "type": "synonym"
                },
                {
                    "name": "CTRCT2",
                    "type": "synonym"
                }
            ],
            "record_id": "P07315-1",
            "evidence": [
                {
                    "id": "604307",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/604307"
                },
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P02529-1",
            "uniprot_ac": "P02529",
            "uniprot_id": "CRGC_RAT",
            "refseq_ac": "NP_001075129",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Gamma-crystallin C",
                    "type": "recommended"
                },
                {
                    "name": "Gamma-C-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-crystallin 2-1",
                    "type": "synonym"
                },
                {
                    "name": "crystallin, gamma polypeptide 3",
                    "type": "synonym"
                },
                {
                    "name": "gamma-C-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin 2-1",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin C isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin C",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Crygc",
                    "type": "recommended"
                },
                {
                    "name": "Cryg3",
                    "type": "synonym"
                },
                {
                    "name": "Crygc",
                    "type": "synonym"
                },
                {
                    "name": "Cryg",
                    "type": "synonym"
                },
                {
                    "name": "Len",
                    "type": "synonym"
                }
            ],
            "record_id": "P02529-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P10067-1",
            "uniprot_ac": "P10067",
            "uniprot_id": "CRGD_RAT",
            "refseq_ac": "NP_149086",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Gamma-crystallin D",
                    "type": "recommended"
                },
                {
                    "name": "Crystallin, gamma polypeptide 4",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-D-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-crystallin 2-2",
                    "type": "synonym"
                },
                {
                    "name": "gamma-D-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin 2-2",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin D",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Crygd",
                    "type": "recommended"
                },
                {
                    "name": "Cryg4",
                    "type": "synonym"
                },
                {
                    "name": "Crygd",
                    "type": "synonym"
                },
                {
                    "name": "Len",
                    "type": "synonym"
                }
            ],
            "record_id": "P10067-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P48199-1",
            "uniprot_ac": "P48199",
            "uniprot_id": "CRP_RAT",
            "refseq_ac": "NP_058792",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "C-reactive protein",
                    "type": "recommended"
                },
                {
                    "name": "C-reactive protein precursor",
                    "type": "synonym"
                },
                {
                    "name": "C-reactive protein, member of the pentraxin family",
                    "type": "synonym"
                },
                {
                    "name": "C-reactive protein, pentraxin-related",
                    "type": "synonym"
                },
                {
                    "name": "C-reactive protein, petaxin related",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Crp",
                    "type": "recommended"
                },
                {
                    "name": "Aa1249",
                    "type": "synonym"
                },
                {
                    "name": "Ab1-341",
                    "type": "synonym"
                },
                {
                    "name": "Ab2-196",
                    "type": "synonym"
                },
                {
                    "name": "Ac1-114",
                    "type": "synonym"
                },
                {
                    "name": "Ac1262",
                    "type": "synonym"
                },
                {
                    "name": "Ac2-069",
                    "type": "synonym"
                },
                {
                    "name": "Ba2-693",
                    "type": "synonym"
                },
                {
                    "name": "Crp",
                    "type": "synonym"
                },
                {
                    "name": "Ptx1",
                    "type": "synonym"
                }
            ],
            "record_id": "P48199-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q62952-1",
            "uniprot_ac": "Q62952",
            "uniprot_id": "DPYL3_RAT",
            "refseq_ac": "NP_037066",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Dihydropyrimidinase-related protein 3",
                    "type": "recommended"
                },
                {
                    "name": "CRMP-4",
                    "type": "synonym"
                },
                {
                    "name": "Collapsin response mediator protein 4",
                    "type": "synonym"
                },
                {
                    "name": "DRP-3",
                    "type": "synonym"
                },
                {
                    "name": "TOAD-64/Ulip/CRMP protein 4b",
                    "type": "synonym"
                },
                {
                    "name": "TOAD-64/Ulip/CRMP",
                    "type": "synonym"
                },
                {
                    "name": "TUC-4b",
                    "type": "synonym"
                },
                {
                    "name": "collapsin response mediator protein 4",
                    "type": "synonym"
                },
                {
                    "name": "dihydropyrimidinase-related protein 3 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "dihydropyrimidinase-related protein 3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Dpysl3",
                    "type": "recommended"
                },
                {
                    "name": "Crmp4",
                    "type": "synonym"
                },
                {
                    "name": "Dpysl3",
                    "type": "synonym"
                },
                {
                    "name": "TUC-4b",
                    "type": "synonym"
                }
            ],
            "record_id": "Q62952-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O75390-1",
            "uniprot_ac": "O75390",
            "uniprot_id": "CISY_HUMAN",
            "refseq_ac": "NP_004068",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Citrate synthase, mitochondrial",
                    "type": "recommended"
                },
                {
                    "name": "2.3.3.1",
                    "type": "synonym"
                },
                {
                    "name": "Citrate (Si)-synthase",
                    "type": "synonym"
                },
                {
                    "name": "citrate (Si)-synthase",
                    "type": "synonym"
                },
                {
                    "name": "citrate synthase, mitochondrial precursor",
                    "type": "synonym"
                },
                {
                    "name": "citrate synthase, mitochondrial",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CS",
                    "type": "recommended"
                },
                {
                    "name": "CS",
                    "type": "synonym"
                }
            ],
            "record_id": "O75390-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P07320-1",
            "uniprot_ac": "P07320",
            "uniprot_id": "CRGD_HUMAN",
            "refseq_ac": "NP_008822",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Gamma-crystallin D",
                    "type": "recommended"
                },
                {
                    "name": "Gamma-D-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-crystallin 4",
                    "type": "synonym"
                },
                {
                    "name": "gamma crystallin 4",
                    "type": "synonym"
                },
                {
                    "name": "gamma-D-crystallin",
                    "type": "synonym"
                },
                {
                    "name": "gamma-crystallin D",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CRYGD",
                    "type": "recommended"
                },
                {
                    "name": "CACA",
                    "type": "synonym"
                },
                {
                    "name": "CCA3",
                    "type": "synonym"
                },
                {
                    "name": "CCP",
                    "type": "synonym"
                },
                {
                    "name": "CRYG4",
                    "type": "synonym"
                },
                {
                    "name": "CRYGD",
                    "type": "synonym"
                },
                {
                    "name": "CTRCT4",
                    "type": "synonym"
                },
                {
                    "name": "PCC",
                    "type": "synonym"
                },
                {
                    "name": "cry-g-D",
                    "type": "synonym"
                }
            ],
            "record_id": "P07320-1",
            "evidence": [
                {
                    "id": "0110235",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110235"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0110235"
}