{
    "disease_id": "DOID:0110106",
    "recommended_name": {
        "id": "DOID:0110106",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0110106",
        "name": "atrial heart septal defect 1",
        "description": "An atrial heart septal defect type 1 associated with variation in the region 5p."
    },
    "synonyms": [
        {
            "id": "DOID:0110106",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110106",
            "name": "ASD1",
            "description": ""
        },
        {
            "id": "DOID:0110106",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110106",
            "name": "atrial septal defect 1",
            "description": ""
        },
        {
            "id": "MONDO:0007172",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007172",
            "name": "atrial septal defect 1",
            "description": "An atrial heart septal defect type 1 associated with variation in the region 5p."
        },
        {
            "id": "MONDO:0007172",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007172",
            "name": "ASD1",
            "description": ""
        },
        {
            "id": "MONDO:0007172",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007172",
            "name": "atrial heart septal defect type 1",
            "description": ""
        },
        {
            "id": "MONDO:0007172",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007172",
            "name": "atrial septal defect 1",
            "description": ""
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0110106"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0110106",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110106",
            "categories": []
        },
        {
            "id": "MONDO:0007172",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007172",
            "categories": []
        }
    ],
    "proteins": [
        {
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            "uniprot_ac": "F1QL10",
            "uniprot_id": "F1QL10_DANRE",
            "refseq_ac": "NP_001001826",
            "glycoprotein": "no",
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                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
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                    "name": "CCN family member 1",
                    "type": "recommended"
                },
                {
                    "name": "CCN family member 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "Cellular communication network factor 1",
                    "type": "synonym"
                },
                {
                    "name": "Protein CYR61",
                    "type": "synonym"
                },
                {
                    "name": "cysteine-rich, angiogenic inducer, 61",
                    "type": "synonym"
                }
            ],
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                    "name": "ccn1",
                    "type": "recommended"
                },
                {
                    "name": "ccn1",
                    "type": "synonym"
                },
                {
                    "name": "cyr61",
                    "type": "synonym"
                },
                {
                    "name": "zCyr61-c23",
                    "type": "synonym"
                },
                {
                    "name": "zgc:85866",
                    "type": "synonym"
                }
            ],
            "record_id": "F1QL10-1",
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                {
                    "id": "0110106",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110106"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8M1P3S4-1",
            "uniprot_ac": "A0A8M1P3S4",
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            "refseq_ac": "NP_001314742",
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                    "common_name": "Zebrafish",
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                }
            ],
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                    "name": "Neurotrophin-3",
                    "type": "recommended"
                },
                {
                    "name": "NT-3",
                    "type": "synonym"
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                {
                    "name": "neurotrophin-3",
                    "type": "synonym"
                }
            ],
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                {
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                },
                {
                    "name": "ntf3",
                    "type": "synonym"
                },
                {
                    "name": "wu:fl98d04",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0110106",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110106"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P20181-1",
            "uniprot_ac": "P20181",
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            "refseq_ac": "NP_001157506",
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                    "taxid": 10090,
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                }
            ],
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                    "name": "Neurotrophin-3",
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                    "name": "HDNF",
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                {
                    "name": "NGF-2",
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                {
                    "name": "NT-3",
                    "type": "synonym"
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                {
                    "name": "Nerve growth factor 2",
                    "type": "synonym"
                },
                {
                    "name": "Neurotrophic factor",
                    "type": "synonym"
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                {
                    "name": "nerve growth factor 2",
                    "type": "synonym"
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                {
                    "name": "neurotrophic factor",
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                {
                    "name": "neurotrophin-3 isoform a precursor",
                    "type": "synonym"
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                    "name": "Ntf3",
                    "type": "recommended"
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                {
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                    "type": "synonym"
                },
                {
                    "name": "NGF-2",
                    "type": "synonym"
                },
                {
                    "name": "Nt3",
                    "type": "synonym"
                },
                {
                    "name": "Ntf-3",
                    "type": "synonym"
                },
                {
                    "name": "Ntf3",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0110106",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110106"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P18406-1",
            "uniprot_ac": "P18406",
            "uniprot_id": "CCN1_MOUSE",
            "refseq_ac": "NP_034646",
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                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
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                    "reference_species": "Mus musculus [10090]"
                }
            ],
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                    "name": "CCN family member 1",
                    "type": "recommended"
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                {
                    "name": "3CH61",
                    "type": "synonym"
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                {
                    "name": "CCN family member 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "CCN family member 1",
                    "type": "synonym"
                },
                {
                    "name": "Cellular communication network factor 1",
                    "type": "synonym"
                },
                {
                    "name": "Cysteine-rich angiogenic inducer 61",
                    "type": "synonym"
                },
                {
                    "name": "IBP-10",
                    "type": "synonym"
                },
                {
                    "name": "IGF-binding protein 10",
                    "type": "synonym"
                },
                {
                    "name": "IGFBP-10",
                    "type": "synonym"
                },
                {
                    "name": "Insulin-like growth factor-binding protein 10",
                    "type": "synonym"
                },
                {
                    "name": "Protein CYR61",
                    "type": "synonym"
                },
                {
                    "name": "cysteine rich protein 61",
                    "type": "synonym"
                },
                {
                    "name": "cysteine-rich angiogenic inducer 61",
                    "type": "synonym"
                },
                {
                    "name": "insulin-like growth factor-binding protein 10",
                    "type": "synonym"
                },
                {
                    "name": "intermediate early",
                    "type": "synonym"
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                {
                    "name": "protein CYR61",
                    "type": "synonym"
                }
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                    "name": "Ccn1",
                    "type": "recommended"
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                    "name": "Cyr61",
                    "type": "synonym"
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                {
                    "name": "Igfbp10",
                    "type": "synonym"
                }
            ],
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                    "id": "0110106",
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                }
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        {
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            "uniprot_ac": "P18280",
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                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
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                    "reference_species": "Rattus norvegicus [10116]"
                }
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                    "name": "Neurotrophin-3",
                    "type": "recommended"
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                    "name": "HDNF",
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                {
                    "name": "NGF-2",
                    "type": "synonym"
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                {
                    "name": "NT-3",
                    "type": "synonym"
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                {
                    "name": "Nerve growth factor 2",
                    "type": "synonym"
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                {
                    "name": "Neurotrophic factor",
                    "type": "synonym"
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                {
                    "name": "neurotrophic factor",
                    "type": "synonym"
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                {
                    "name": "neurotrophin-3 (HDNF/NT-3)",
                    "type": "synonym"
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                {
                    "name": "neurotrophin-3 isoform 2 precursor",
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            ],
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                    "name": "Ntf3",
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                {
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                {
                    "name": "Ntf3",
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            "record_id": "P18280-1",
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                {
                    "id": "0110106",
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                }
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        },
        {
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            "uniprot_ac": "Q9ES72",
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                    "name": "Rattus norvegicus",
                    "taxid": 10116,
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                }
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                {
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                {
                    "name": "IGF-binding protein 10",
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                {
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                {
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                    "name": "Cyr61",
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                    "id": "0110106",
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        {
            "uniprot_canonical_ac": "P48317-1",
            "uniprot_ac": "P48317",
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                {
                    "name": "DDIT-1",
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                {
                    "name": "DNA damage-inducible transcript 1 protein",
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                    "name": "Gadd45a",
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                {
                    "name": "Ddit1",
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                {
                    "name": "Gadd45",
                    "type": "synonym"
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            "record_id": "P48317-1",
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                {
                    "id": "0110106",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110106"
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        {
            "uniprot_canonical_ac": "Q9VVK3-1",
            "uniprot_ac": "Q9VVK3",
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            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
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                    "name": "CG32183-PB",
                    "type": "synonym"
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                {
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                {
                    "name": "Ccn",
                    "type": "synonym"
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                    "name": "CG13735",
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                {
                    "name": "CG13736",
                    "type": "synonym"
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                {
                    "name": "CG32183",
                    "type": "synonym"
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                {
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                {
                    "name": "Dmel\\CG32183",
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                {
                    "name": "Dmel_CG32183",
                    "type": "synonym"
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                {
                    "name": "dCCN",
                    "type": "synonym"
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                {
                    "id": "0110106",
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        {
            "uniprot_canonical_ac": "P20783-1",
            "uniprot_ac": "P20783",
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                    "name": "Homo sapiens",
                    "taxid": 9606,
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                    "name": "Neurotrophin-3",
                    "type": "recommended"
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                    "name": "NGF-2",
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                {
                    "name": "NT-3",
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                {
                    "name": "Nerve growth factor 2",
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                {
                    "name": "Neurotrophic factor",
                    "type": "synonym"
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                    "name": "nerve growth factor 2",
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                {
                    "name": "neurotrophic factor",
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                    "name": "neurotrophin-3 isoform 1 preproprotein",
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                    "name": "NTF3",
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                    "type": "synonym"
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                {
                    "name": "NT3",
                    "type": "synonym"
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                    "name": "NTF3",
                    "type": "synonym"
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                    "id": "0110106",
                    "database": "AGR",
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                    "taxid": 9606,
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                    "name": "CCN family member 1",
                    "type": "recommended"
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                {
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                {
                    "name": "CCN family member 1",
                    "type": "synonym"
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                {
                    "name": "Cellular communication network factor 1",
                    "type": "synonym"
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                {
                    "name": "Cysteine-rich angiogenic inducer 61",
                    "type": "synonym"
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                {
                    "name": "IBP-10",
                    "type": "synonym"
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                {
                    "name": "IGF-binding protein 10",
                    "type": "synonym"
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                {
                    "name": "IGFBP-10",
                    "type": "synonym"
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                {
                    "name": "Insulin-like growth factor-binding protein 10",
                    "type": "synonym"
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                {
                    "name": "Protein CYR61",
                    "type": "synonym"
                },
                {
                    "name": "Protein GIG1",
                    "type": "synonym"
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                {
                    "name": "cysteine rich angiogenic inducer 61",
                    "type": "synonym"
                },
                {
                    "name": "cysteine-rich heparin-binding protein 61",
                    "type": "synonym"
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                {
                    "name": "cysteine-rich, anigogenic inducer, 61",
                    "type": "synonym"
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                {
                    "name": "insulin-like growth factor-binding protein 10",
                    "type": "synonym"
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                {
                    "name": "protein CYR61",
                    "type": "synonym"
                }
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                    "name": "CCN1",
                    "type": "recommended"
                },
                {
                    "name": "CCN1",
                    "type": "synonym"
                },
                {
                    "name": "CYR61",
                    "type": "synonym"
                },
                {
                    "name": "GIG1",
                    "type": "synonym"
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                {
                    "name": "IBP-10",
                    "type": "synonym"
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                {
                    "name": "IGFBP-10",
                    "type": "synonym"
                },
                {
                    "name": "IGFBP10",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0110106",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110106"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0110106"
}