{
    "disease_id": "DOID:0110049",
    "recommended_name": {
        "id": "DOID:0110049",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0110049",
        "name": "Alzheimer's disease 17",
        "description": "An Alzheimer's disease that is characterized by an associated with mutations in the gene TREM2."
    },
    "synonyms": [
        {
            "id": "DOID:0110049",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110049",
            "name": "AD17",
            "description": ""
        },
        {
            "id": "DOID:0110049",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110049",
            "name": "Alzheimer disease 17",
            "description": ""
        },
        {
            "id": "DOID:0110049",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110049",
            "name": "Alzheimer disease 17, late onset",
            "description": ""
        },
        {
            "id": "MONDO:0014036",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014036",
            "name": "Alzheimer disease 17",
            "description": "An Alzheimer's disease that is characterized by an associated with mutations in the gene TREM2."
        },
        {
            "id": "MONDO:0014036",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014036",
            "name": "AD17",
            "description": ""
        },
        {
            "id": "MONDO:0014036",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014036",
            "name": "Alzheimer disease 17",
            "description": ""
        },
        {
            "id": "MONDO:0014036",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014036",
            "name": "Alzheimer's disease 17",
            "description": ""
        },
        {
            "id": "MONDO:0014036",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014036",
            "name": "Alzheimer's disease type 17",
            "description": ""
        },
        {
            "id": "MIM:615080",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/615080",
            "name": "Alzheimer disease 17",
            "description": "Alzheimer disease 17"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0110049"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0110049",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110049",
            "categories": []
        },
        {
            "id": "MONDO:0014036",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014036",
            "categories": []
        },
        {
            "id": "MIM:615080",
            "database": "MIM",
            "url": "https://www.omim.org/entry/615080",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q99NH8-1",
            "uniprot_ac": "Q99NH8",
            "uniprot_id": "TREM2_MOUSE",
            "refseq_ac": "NP_001259007",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Triggering receptor expressed on myeloid cells 2",
                    "type": "recommended"
                },
                {
                    "name": "TREM-2",
                    "type": "synonym"
                },
                {
                    "name": "Triggering receptor expressed on monocytes 2",
                    "type": "synonym"
                },
                {
                    "name": "triggering receptor expressed on monocytes 2",
                    "type": "synonym"
                },
                {
                    "name": "triggering receptor expressed on myeloid cells 2 isoform 2 precursor",
                    "type": "synonym"
                },
                {
                    "name": "triggering receptor expressed on myeloid cells 2a",
                    "type": "synonym"
                },
                {
                    "name": "triggering receptor expressed on myeloid cells 2b",
                    "type": "synonym"
                },
                {
                    "name": "triggering receptor expressed on myeloid cells 2c",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Trem2",
                    "type": "recommended"
                },
                {
                    "name": "TREM-2",
                    "type": "synonym"
                },
                {
                    "name": "Trem2a",
                    "type": "synonym"
                },
                {
                    "name": "Trem2b",
                    "type": "synonym"
                },
                {
                    "name": "Trem2c",
                    "type": "synonym"
                },
                {
                    "name": "Trem2",
                    "type": "synonym"
                }
            ],
            "record_id": "Q99NH8-1",
            "evidence": [
                {
                    "id": "0110049",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110049"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9NZC2-1",
            "uniprot_ac": "Q9NZC2",
            "uniprot_id": "TREM2_HUMAN",
            "refseq_ac": "NP_001258750",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Triggering receptor expressed on myeloid cells 2",
                    "type": "recommended"
                },
                {
                    "name": "TREM-2",
                    "type": "synonym"
                },
                {
                    "name": "Triggering receptor expressed on monocytes 2",
                    "type": "synonym"
                },
                {
                    "name": "triggering receptor expressed on monocytes 2",
                    "type": "synonym"
                },
                {
                    "name": "triggering receptor expressed on myeloid cells 2 isoform 2 precursor",
                    "type": "synonym"
                },
                {
                    "name": "triggering receptor expressed on myeloid cells 2a",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "TREM2",
                    "type": "recommended"
                },
                {
                    "name": "AD17",
                    "type": "synonym"
                },
                {
                    "name": "PLOSL2",
                    "type": "synonym"
                },
                {
                    "name": "TREM-2",
                    "type": "synonym"
                },
                {
                    "name": "TREM2",
                    "type": "synonym"
                },
                {
                    "name": "Trem2a",
                    "type": "synonym"
                },
                {
                    "name": "Trem2b",
                    "type": "synonym"
                },
                {
                    "name": "Trem2c",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9NZC2-1",
            "evidence": [
                {
                    "id": "615080",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/615080"
                },
                {
                    "id": "0110049",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110049"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "D3ZZ89-1",
            "uniprot_ac": "D3ZZ89",
            "uniprot_id": "D3ZZ89_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Triggering receptor expressed on myeloid cells 2",
                    "type": "recommended"
                },
                {
                    "name": "Triggering receptor expressed on monocytes 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Trem2",
                    "type": "recommended"
                }
            ],
            "record_id": "D3ZZ89-1",
            "evidence": [
                {
                    "id": "0110049",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110049"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0110049"
}