{
    "disease_id": "DOID:0081394",
    "recommended_name": {
        "id": "DOID:0081394",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0081394",
        "name": "Caroli syndrome",
        "description": "A syndrome that is characterized by the presence of associated congenital hepatic fibrosis and that is associated with autosomal recessive polycystic kidney disease."
    },
    "synonyms": [],
    "children": [],
    "id_list": [
        "DOID:0081394"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0081394",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0081394",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "E9PZ36-1",
            "uniprot_ac": "E9PZ36",
            "uniprot_id": "PKHD1_MOUSE",
            "refseq_ac": "NP_694819",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Fibrocystin",
                    "type": "recommended"
                },
                {
                    "name": "Polycystic kidney and hepatic disease 1 protein",
                    "type": "synonym"
                },
                {
                    "name": "Polyductin",
                    "type": "synonym"
                },
                {
                    "name": "TIG multiple domains 1",
                    "type": "synonym"
                },
                {
                    "name": "fibrocystin precursor",
                    "type": "synonym"
                },
                {
                    "name": "fibrocystin",
                    "type": "synonym"
                },
                {
                    "name": "polycystic kidney and hepatic disease 1 protein",
                    "type": "synonym"
                },
                {
                    "name": "polyductin",
                    "type": "synonym"
                },
                {
                    "name": "tigmin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pkhd1",
                    "type": "recommended"
                },
                {
                    "name": "FPC",
                    "type": "synonym"
                },
                {
                    "name": "Pkhd1",
                    "type": "synonym"
                },
                {
                    "name": "Tigm1",
                    "type": "synonym"
                }
            ],
            "record_id": "E9PZ36-1",
            "evidence": [
                {
                    "id": "0081394",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081394"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2K2W1-1",
            "uniprot_ac": "A0A0G2K2W1",
            "uniprot_id": "A0A0G2K2W1_RAT",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Fibrocystin",
                    "type": "recommended"
                },
                {
                    "name": "Polycystic kidney and hepatic disease 1 protein",
                    "type": "synonym"
                },
                {
                    "name": "Polyductin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pkhd1",
                    "type": "recommended"
                }
            ],
            "record_id": "A0A0G2K2W1-1",
            "evidence": [
                {
                    "id": "0081394",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081394"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P08F94-1",
            "uniprot_ac": "P08F94",
            "uniprot_id": "PKHD1_HUMAN",
            "refseq_ac": "NP_619639",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Fibrocystin",
                    "type": "recommended"
                },
                {
                    "name": "PKHD1, fibrocystin/polyductin",
                    "type": "synonym"
                },
                {
                    "name": "Polycystic kidney and hepatic disease 1 protein",
                    "type": "synonym"
                },
                {
                    "name": "Polyductin",
                    "type": "synonym"
                },
                {
                    "name": "TIG multiple domains 1",
                    "type": "synonym"
                },
                {
                    "name": "Tigmin",
                    "type": "synonym"
                },
                {
                    "name": "fibrocystin isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "fibrocystin/polyductin complex",
                    "type": "synonym"
                },
                {
                    "name": "fibrocystin",
                    "type": "synonym"
                },
                {
                    "name": "polycystic kidney and hepatic disease 1 (autosomal recessive)",
                    "type": "synonym"
                },
                {
                    "name": "polycystic kidney and hepatic disease 1 protein",
                    "type": "synonym"
                },
                {
                    "name": "polyductin",
                    "type": "synonym"
                },
                {
                    "name": "tigmin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "PKHD1",
                    "type": "recommended"
                },
                {
                    "name": "ARPKD",
                    "type": "synonym"
                },
                {
                    "name": "FCYT",
                    "type": "synonym"
                },
                {
                    "name": "FPC",
                    "type": "synonym"
                },
                {
                    "name": "PCYT",
                    "type": "synonym"
                },
                {
                    "name": "PKD4",
                    "type": "synonym"
                },
                {
                    "name": "PKHD1",
                    "type": "synonym"
                },
                {
                    "name": "TIGM1",
                    "type": "synonym"
                }
            ],
            "record_id": "P08F94-1",
            "evidence": [
                {
                    "id": "0081394",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081394"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0081394"
}