{
    "disease_id": "DOID:0081373",
    "recommended_name": {
        "id": "DOID:0081373",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0081373",
        "name": "disabling pansclerotic morphea",
        "description": "A localized scleroderma that is characterized by the rapid progression of deep cutaneous fibrosis or pansclerosis that involves the subcutaneous adipose tissue and, occasionally, the fascia, muscles, and bone."
    },
    "synonyms": [
        {
            "id": "DOID:0081373",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0081373",
            "name": "disabling pansclerotic morphea of childhood",
            "description": ""
        },
        {
            "id": "MONDO:0957497",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957497",
            "name": "disabling pansclerotic morphea of childhood",
            "description": ""
        },
        {
            "id": "MIM:620443",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/620443",
            "name": "Disabling pansclerotic morphea of childhood",
            "description": "Disabling pansclerotic morphea of childhood"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0081373"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0081373",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0081373",
            "categories": []
        },
        {
            "id": "MONDO:0957497",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957497",
            "categories": []
        },
        {
            "id": "MIM:620443",
            "database": "MIM",
            "url": "https://www.omim.org/entry/620443",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8M2BFB6-1",
            "uniprot_ac": "A0A8M2BFB6",
            "uniprot_id": "A0A8M2BFB6_DANRE",
            "refseq_ac": "XP_005167937",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Signal transducer and activator of transcription",
                    "type": "recommended"
                },
                {
                    "name": "signal transducer and activator of transcription 4 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "stat4",
                    "type": "recommended"
                },
                {
                    "name": "STAT1",
                    "type": "synonym"
                },
                {
                    "name": "STAT",
                    "type": "synonym"
                },
                {
                    "name": "dZ182H3.3",
                    "type": "synonym"
                },
                {
                    "name": "si:by134g18.2",
                    "type": "synonym"
                },
                {
                    "name": "si:by51f19.1",
                    "type": "synonym"
                },
                {
                    "name": "si:dz182h3.3",
                    "type": "synonym"
                },
                {
                    "name": "si:dz199m19.1",
                    "type": "synonym"
                },
                {
                    "name": "si:dz73o4.2",
                    "type": "synonym"
                },
                {
                    "name": "stat4",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M2BFB6-1",
            "evidence": [
                {
                    "id": "0081373",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081373"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P42228-1",
            "uniprot_ac": "P42228",
            "uniprot_id": "STAT4_MOUSE",
            "refseq_ac": "NP_001295195",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Signal transducer and activator of transcription 4",
                    "type": "recommended"
                },
                {
                    "name": "signal transducer and activator of transcription 4",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Stat4",
                    "type": "recommended"
                },
                {
                    "name": "Stat4",
                    "type": "synonym"
                }
            ],
            "record_id": "P42228-1",
            "evidence": [
                {
                    "id": "0081373",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081373"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q14765-1",
            "uniprot_ac": "Q14765",
            "uniprot_id": "STAT4_HUMAN",
            "refseq_ac": "NP_001230764",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Signal transducer and activator of transcription 4",
                    "type": "recommended"
                },
                {
                    "name": "signal transducer and activator of transcription 4",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "STAT4",
                    "type": "recommended"
                },
                {
                    "name": "DPMC",
                    "type": "synonym"
                },
                {
                    "name": "SLEB11",
                    "type": "synonym"
                },
                {
                    "name": "STAT4",
                    "type": "synonym"
                }
            ],
            "record_id": "Q14765-1",
            "evidence": [
                {
                    "id": "620443",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/620443"
                },
                {
                    "id": "0081373",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081373"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "F1M9D6-1",
            "uniprot_ac": "F1M9D6",
            "uniprot_id": "F1M9D6_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Signal transducer and activator of transcription",
                    "type": "recommended"
                }
            ],
            "gene_names": [
                {
                    "name": "Stat1",
                    "type": "recommended"
                },
                {
                    "name": "Stat4",
                    "type": "synonym"
                }
            ],
            "record_id": "F1M9D6-1",
            "evidence": [
                {
                    "id": "0081373",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081373"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0081373"
}