{
    "disease_id": "DOID:0080475",
    "recommended_name": {
        "id": "DOID:0080475",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0080475",
        "name": "psoriasis 2",
        "description": "A psoriasis that has_material_basis_in heterozygous mutation in the CARD14 gene on chromosome 17q25."
    },
    "synonyms": [
        {
            "id": "MONDO:0011269",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011269",
            "name": "psoriasis 2",
            "description": "Any psoriasis in which the cause of the disease is a mutation in the CARD14 gene."
        },
        {
            "id": "MONDO:0011269",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011269",
            "name": "CARD14 psoriasis",
            "description": ""
        },
        {
            "id": "MONDO:0011269",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011269",
            "name": "psoriasis 2",
            "description": ""
        },
        {
            "id": "MONDO:0011269",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011269",
            "name": "psoriasis caused by mutation in CARD14",
            "description": ""
        },
        {
            "id": "MONDO:0011269",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011269",
            "name": "psoriasis type 2",
            "description": ""
        },
        {
            "id": "MONDO:0011269",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011269",
            "name": "PSORS2",
            "description": ""
        },
        {
            "id": "MIM:602723",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/602723",
            "name": "Psoriasis 2",
            "description": "Psoriasis 2"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0080475"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0080475",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080475",
            "categories": []
        },
        {
            "id": "MONDO:0011269",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011269",
            "categories": []
        },
        {
            "id": "MIM:602723",
            "database": "MIM",
            "url": "https://www.omim.org/entry/602723",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8M9Q0C3-1",
            "uniprot_ac": "A0A8M9Q0C3",
            "uniprot_id": "A0A8M9Q0C3_DANRE",
            "refseq_ac": "XP_021332748",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Caspase recruitment domain-containing protein 14",
                    "type": "recommended"
                },
                {
                    "name": "caspase recruitment domain-containing protein 14",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "card14",
                    "type": "recommended"
                },
                {
                    "name": "card14",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M9Q0C3-1",
            "evidence": [
                {
                    "id": "0080475",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080475"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q99KF0-1",
            "uniprot_ac": "Q99KF0",
            "uniprot_id": "CAR14_MOUSE",
            "refseq_ac": "NP_570956",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Caspase recruitment domain-containing protein 14",
                    "type": "recommended"
                },
                {
                    "name": "Bcl10-interacting MAGUK protein 2",
                    "type": "synonym"
                },
                {
                    "name": "Bimp2",
                    "type": "synonym"
                },
                {
                    "name": "bcl10-interacting MAGUK protein 2",
                    "type": "synonym"
                },
                {
                    "name": "caspase recruitment domain-containing protein 14",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Card14",
                    "type": "recommended"
                },
                {
                    "name": "Bimp2",
                    "type": "synonym"
                },
                {
                    "name": "CARMA2",
                    "type": "synonym"
                },
                {
                    "name": "Card14",
                    "type": "synonym"
                }
            ],
            "record_id": "Q99KF0-1",
            "evidence": [
                {
                    "id": "0080475",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080475"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9BXL6-1",
            "uniprot_ac": "Q9BXL6",
            "uniprot_id": "CAR14_HUMAN",
            "refseq_ac": "NP_001244899",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Caspase recruitment domain-containing protein 14",
                    "type": "recommended"
                },
                {
                    "name": "CARD-containing MAGUK protein 2",
                    "type": "synonym"
                },
                {
                    "name": "Carma 2",
                    "type": "synonym"
                },
                {
                    "name": "bcl10-interacting maguk protein 2",
                    "type": "synonym"
                },
                {
                    "name": "caspase recruitment domain-containing protein 14 isoform 3",
                    "type": "synonym"
                },
                {
                    "name": "caspase recruitment domain-containing protein 14",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CARD14",
                    "type": "recommended"
                },
                {
                    "name": "BIMP2",
                    "type": "synonym"
                },
                {
                    "name": "CARD14",
                    "type": "synonym"
                },
                {
                    "name": "CARMA2",
                    "type": "synonym"
                },
                {
                    "name": "PRP",
                    "type": "synonym"
                },
                {
                    "name": "PSORS2",
                    "type": "synonym"
                },
                {
                    "name": "PSS1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9BXL6-1",
            "evidence": [
                {
                    "id": "602723",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/602723"
                },
                {
                    "id": "0080475",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080475"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "M0R6R8-1",
            "uniprot_ac": "M0R6R8",
            "uniprot_id": "M0R6R8_RAT",
            "refseq_ac": "XP_038943451",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Caspase recruitment domain-containing protein 14",
                    "type": "recommended"
                },
                {
                    "name": "caspase recruitment domain-containing protein 14 isoform X4",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Card14",
                    "type": "recommended"
                },
                {
                    "name": "Card14",
                    "type": "synonym"
                },
                {
                    "name": "LOC688292",
                    "type": "synonym"
                }
            ],
            "record_id": "M0R6R8-1",
            "evidence": [
                {
                    "id": "0080475",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080475"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0080475"
}