{
    "disease_id": "DOID:0080356",
    "recommended_name": {
        "id": "DOID:0080356",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0080356",
        "name": "IgG4-related disease",
        "description": "An autoimmune disease that is characterized by tumefactive lesions, a dense lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells, storiform fibrosis, obliterative phlebitis, autoimmune pancreatitis, and sometimes elevated serum IgG4 levels affecting various organs."
    },
    "synonyms": [],
    "children": [],
    "id_list": [
        "DOID:0080356"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0080356",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080356",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A0G2KG91-1",
            "uniprot_ac": "A0A0G2KG91",
            "uniprot_id": "A0A0G2KG91_DANRE",
            "refseq_ac": "NP_001137156",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Linker for activation of T-cells family member 1",
                    "type": "synonym"
                },
                {
                    "name": "linker for activation of T-cells family member 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "lat",
                    "type": "recommended"
                },
                {
                    "name": "lat",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0G2KG91-1",
            "evidence": [
                {
                    "id": "0080356",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080356"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O54957-1",
            "uniprot_ac": "O54957",
            "uniprot_id": "LAT_MOUSE",
            "refseq_ac": "NP_034819",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Linker for activation of T-cells family member 1",
                    "type": "recommended"
                },
                {
                    "name": "36 kDa phospho-tyrosine adapter protein",
                    "type": "synonym"
                },
                {
                    "name": "36 kDa phosphotyrosine adapter protein",
                    "type": "synonym"
                },
                {
                    "name": "linker for activation of T-cells family member 1",
                    "type": "synonym"
                },
                {
                    "name": "linker protein",
                    "type": "synonym"
                },
                {
                    "name": "p36-38",
                    "type": "synonym"
                },
                {
                    "name": "pp36",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Lat",
                    "type": "recommended"
                },
                {
                    "name": "Lat",
                    "type": "synonym"
                },
                {
                    "name": "p36-38",
                    "type": "synonym"
                },
                {
                    "name": "pp36",
                    "type": "synonym"
                }
            ],
            "record_id": "O54957-1",
            "evidence": [
                {
                    "id": "0080356",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080356"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O70601-1",
            "uniprot_ac": "O70601",
            "uniprot_id": "LAT_RAT",
            "refseq_ac": "NP_110480",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Linker for activation of T-cells family member 1",
                    "type": "recommended"
                },
                {
                    "name": "36 kDa phospho-tyrosine adapter protein",
                    "type": "synonym"
                },
                {
                    "name": "36 kDa phosphotyrosine adapter protein",
                    "type": "synonym"
                },
                {
                    "name": "linker for activation of T-cells family member 1",
                    "type": "synonym"
                },
                {
                    "name": "p36-38",
                    "type": "synonym"
                },
                {
                    "name": "pp36",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Lat",
                    "type": "recommended"
                },
                {
                    "name": "Lat",
                    "type": "synonym"
                }
            ],
            "record_id": "O70601-1",
            "evidence": [
                {
                    "id": "0080356",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080356"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P24001-1",
            "uniprot_ac": "P24001",
            "uniprot_id": "IL32_HUMAN",
            "refseq_ac": "NP_001012649",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Interleukin-32",
                    "type": "recommended"
                },
                {
                    "name": "IL-32",
                    "type": "synonym"
                },
                {
                    "name": "Natural killer cells protein 4",
                    "type": "synonym"
                },
                {
                    "name": "Tumor necrosis factor alpha-inducing factor",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-32 eta",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-32 isoform B",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-32 small",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-32 theta",
                    "type": "synonym"
                },
                {
                    "name": "natural killer cell transcript 4",
                    "type": "synonym"
                },
                {
                    "name": "natural killer cells protein 4",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor alpha-inducing factor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "IL32",
                    "type": "recommended"
                },
                {
                    "name": "IL-32alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL-32beta",
                    "type": "synonym"
                },
                {
                    "name": "IL-32delta",
                    "type": "synonym"
                },
                {
                    "name": "IL-32gamma",
                    "type": "synonym"
                },
                {
                    "name": "IL32",
                    "type": "synonym"
                },
                {
                    "name": "NK4",
                    "type": "synonym"
                },
                {
                    "name": "TAIFa",
                    "type": "synonym"
                },
                {
                    "name": "TAIFb",
                    "type": "synonym"
                },
                {
                    "name": "TAIFc",
                    "type": "synonym"
                },
                {
                    "name": "TAIFd",
                    "type": "synonym"
                },
                {
                    "name": "TAIF",
                    "type": "synonym"
                }
            ],
            "record_id": "P24001-1",
            "evidence": [
                {
                    "id": "0080356",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080356"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O43561-1",
            "uniprot_ac": "O43561",
            "uniprot_id": "LAT_HUMAN",
            "refseq_ac": "NP_001014987",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Linker for activation of T-cells family member 1",
                    "type": "recommended"
                },
                {
                    "name": "36 kDa phospho-tyrosine adapter protein",
                    "type": "synonym"
                },
                {
                    "name": "36 kDa phospho-tyrosine adaptor protein",
                    "type": "synonym"
                },
                {
                    "name": "36 kDa phosphotyrosine adapter protein",
                    "type": "synonym"
                },
                {
                    "name": "linker for activation of T cells, transmembrane adaptor",
                    "type": "synonym"
                },
                {
                    "name": "linker for activation of T-cells family member 1 isoform b",
                    "type": "synonym"
                },
                {
                    "name": "linker for activation of T-cells family member 1",
                    "type": "synonym"
                },
                {
                    "name": "p36-38",
                    "type": "synonym"
                },
                {
                    "name": "pp36",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "LAT",
                    "type": "recommended"
                },
                {
                    "name": "IMD52",
                    "type": "synonym"
                },
                {
                    "name": "LAT1",
                    "type": "synonym"
                },
                {
                    "name": "LAT",
                    "type": "synonym"
                },
                {
                    "name": "pp36",
                    "type": "synonym"
                }
            ],
            "record_id": "O43561-1",
            "evidence": [
                {
                    "id": "0080356",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080356"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0080356"
}