{
    "disease_id": "DOID:0080072",
    "recommended_name": {
        "id": "DOID:0080072",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0080072",
        "name": "intestinal pseudo-obstruction",
        "description": "A colonic disease that is characterized by bowel obstruction resulting from impairment of the muscle contractions that move food through the digestive tract."
    },
    "synonyms": [
        {
            "id": "DOID:0080072",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080072",
            "name": "Chronic intestinal pseudo-obstruction",
            "description": ""
        },
        {
            "id": "DOID:0080072",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080072",
            "name": "neuronal intestinal dysplasia",
            "description": ""
        }
    ],
    "children": [
        {
            "id": "DOID:0080679",
            "label": "neuronal intestinal dysplasia type A",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0080681",
            "label": "X-linked chronic idiopathic intestinal pseudo-obstruction",
            "link_status": true,
            "children": []
        }
    ],
    "id_list": [
        "DOID:0080679",
        "DOID:0080681",
        "DOID:0080072"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0080072",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080072",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8M1PHN1-1",
            "uniprot_ac": "A0A8M1PHN1",
            "uniprot_id": "A0A8M1PHN1_DANRE",
            "refseq_ac": "NP_957002",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.16",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.48",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.67",
                    "type": "synonym"
                },
                {
                    "name": "Phosphatase and tensin homolog",
                    "type": "synonym"
                },
                {
                    "name": "phosphatase and tensin homolog A",
                    "type": "synonym"
                },
                {
                    "name": "phosphatase and tensin-like protein A",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ptena",
                    "type": "recommended"
                },
                {
                    "name": "ptena",
                    "type": "synonym"
                },
                {
                    "name": "wu:fc52g04",
                    "type": "synonym"
                },
                {
                    "name": "zgc:73086",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M1PHN1-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q6P6X9-1",
            "uniprot_ac": "Q6P6X9",
            "uniprot_id": "NUP35_DANRE",
            "refseq_ac": "NP_956360",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Nucleoporin NUP35",
                    "type": "recommended"
                },
                {
                    "name": "35 kDa nucleoporin",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear pore complex protein Nup53",
                    "type": "synonym"
                },
                {
                    "name": "Nucleoporin NUP53",
                    "type": "synonym"
                },
                {
                    "name": "nuclear pore complex protein Nup53",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin NUP35",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin NUP53",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "nup35",
                    "type": "recommended"
                },
                {
                    "name": "fj68d11",
                    "type": "synonym"
                },
                {
                    "name": "nup35",
                    "type": "synonym"
                },
                {
                    "name": "nup53",
                    "type": "synonym"
                },
                {
                    "name": "wu:fj68d11",
                    "type": "synonym"
                },
                {
                    "name": "zgc:65979",
                    "type": "synonym"
                }
            ],
            "record_id": "Q6P6X9-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "F1QU39-1",
            "uniprot_ac": "F1QU39",
            "uniprot_id": "F1QU39_DANRE",
            "refseq_ac": "XP_005160342",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein sprouty homolog 2",
                    "type": "recommended"
                },
                {
                    "name": "protein sprouty homolog 2 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "spry2",
                    "type": "recommended"
                },
                {
                    "name": "spry2",
                    "type": "synonym"
                },
                {
                    "name": "wu:fk66h11",
                    "type": "synonym"
                },
                {
                    "name": "wu:fk93e11",
                    "type": "synonym"
                },
                {
                    "name": "zgc:110440",
                    "type": "synonym"
                }
            ],
            "record_id": "F1QU39-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A2R8QHC0-1",
            "uniprot_ac": "A0A2R8QHC0",
            "uniprot_id": "A0A2R8QHC0_DANRE",
            "refseq_ac": "XP_005173139",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "T-cell leukemia homeobox protein 2 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "tlx2",
                    "type": "recommended"
                },
                {
                    "name": "Tlx-3a",
                    "type": "synonym"
                },
                {
                    "name": "hox11l",
                    "type": "synonym"
                },
                {
                    "name": "tlx2",
                    "type": "synonym"
                },
                {
                    "name": "tlx3a",
                    "type": "synonym"
                },
                {
                    "name": "tlxA",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A2R8QHC0-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9QXV8-1",
            "uniprot_ac": "Q9QXV8",
            "uniprot_id": "SPY2_MOUSE",
            "refseq_ac": "NP_036027",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein sprouty homolog 2",
                    "type": "recommended"
                },
                {
                    "name": "Spry-2",
                    "type": "synonym"
                },
                {
                    "name": "protein sprouty homolog 2",
                    "type": "synonym"
                },
                {
                    "name": "sprouty homolog 2",
                    "type": "synonym"
                },
                {
                    "name": "spry-2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Spry2",
                    "type": "recommended"
                },
                {
                    "name": "Spry2",
                    "type": "synonym"
                },
                {
                    "name": "sprouty2",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9QXV8-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q8R4R6-1",
            "uniprot_ac": "Q8R4R6",
            "uniprot_id": "NUP35_MOUSE",
            "refseq_ac": "NP_001177108",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Nucleoporin NUP35",
                    "type": "recommended"
                },
                {
                    "name": "35 kDa nucleoporin",
                    "type": "synonym"
                },
                {
                    "name": "MP-44",
                    "type": "synonym"
                },
                {
                    "name": "Mitotic phosphoprotein 44",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear pore complex protein Nup53",
                    "type": "synonym"
                },
                {
                    "name": "Nucleoporin NUP53",
                    "type": "synonym"
                },
                {
                    "name": "mitotic phosphoprotein 44",
                    "type": "synonym"
                },
                {
                    "name": "nuclear pore complex protein Nup53",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin NUP35 isoform 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Nup35",
                    "type": "recommended"
                },
                {
                    "name": "2310006I24Rik",
                    "type": "synonym"
                },
                {
                    "name": "35kDa",
                    "type": "synonym"
                },
                {
                    "name": "5330402E05Rik",
                    "type": "synonym"
                },
                {
                    "name": "MP44",
                    "type": "synonym"
                },
                {
                    "name": "Mp44",
                    "type": "synonym"
                },
                {
                    "name": "NO44",
                    "type": "synonym"
                },
                {
                    "name": "Nup35",
                    "type": "synonym"
                },
                {
                    "name": "Nup53",
                    "type": "synonym"
                }
            ],
            "record_id": "Q8R4R6-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q61663-1",
            "uniprot_ac": "Q61663",
            "uniprot_id": "TLX2_MOUSE",
            "refseq_ac": "NP_033418",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "T-cell leukemia homeobox protein 2",
                    "type": "recommended"
                },
                {
                    "name": "Enteric neuron homeobox protein",
                    "type": "synonym"
                },
                {
                    "name": "Homeobox TLX-2",
                    "type": "synonym"
                },
                {
                    "name": "Homeobox protein Hox-11L1",
                    "type": "synonym"
                },
                {
                    "name": "Hox11L.1",
                    "type": "synonym"
                },
                {
                    "name": "PMUR10F",
                    "type": "synonym"
                },
                {
                    "name": "T-cell leukemia homeobox protein 2",
                    "type": "synonym"
                },
                {
                    "name": "enteric neuron homeobox protein",
                    "type": "synonym"
                },
                {
                    "name": "homeo box 11-like 1",
                    "type": "synonym"
                },
                {
                    "name": "homeobox TLX-2",
                    "type": "synonym"
                },
                {
                    "name": "homeobox protein Hox-11L1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Tlx2",
                    "type": "recommended"
                },
                {
                    "name": "Enx",
                    "type": "synonym"
                },
                {
                    "name": "Hox11L.1",
                    "type": "synonym"
                },
                {
                    "name": "Hox11l1",
                    "type": "synonym"
                },
                {
                    "name": "NCX",
                    "type": "synonym"
                },
                {
                    "name": "Ncx1",
                    "type": "synonym"
                },
                {
                    "name": "Ncx",
                    "type": "synonym"
                },
                {
                    "name": "Tlx1l1",
                    "type": "synonym"
                },
                {
                    "name": "Tlx1l2",
                    "type": "synonym"
                },
                {
                    "name": "Tlx2",
                    "type": "synonym"
                }
            ],
            "record_id": "Q61663-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O08586-1",
            "uniprot_ac": "O08586",
            "uniprot_id": "PTEN_MOUSE",
            "refseq_ac": "NP_032986",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.-",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.16",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.48",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.67",
                    "type": "synonym"
                },
                {
                    "name": "Inositol polyphosphate 3-phosphatase",
                    "type": "synonym"
                },
                {
                    "name": "Mutated in multiple advanced cancers 1",
                    "type": "synonym"
                },
                {
                    "name": "PTENepsilon",
                    "type": "synonym"
                },
                {
                    "name": "Phosphatase and tensin homolog",
                    "type": "synonym"
                },
                {
                    "name": "inositol polyphosphate 3-phosphatase",
                    "type": "synonym"
                },
                {
                    "name": "mitochondrial PTENalpha",
                    "type": "synonym"
                },
                {
                    "name": "mutated in multiple advanced cancers 1",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pten",
                    "type": "recommended"
                },
                {
                    "name": "2310035O07Rik",
                    "type": "synonym"
                },
                {
                    "name": "A130070J02Rik",
                    "type": "synonym"
                },
                {
                    "name": "B430203M17Rik",
                    "type": "synonym"
                },
                {
                    "name": "MMAC1",
                    "type": "synonym"
                },
                {
                    "name": "Mmac1",
                    "type": "synonym"
                },
                {
                    "name": "PTENbeta",
                    "type": "synonym"
                },
                {
                    "name": "Pten",
                    "type": "synonym"
                },
                {
                    "name": "TEP1",
                    "type": "synonym"
                }
            ],
            "record_id": "O08586-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P53916-1",
            "uniprot_ac": "P53916",
            "uniprot_id": "TEP1_YEAST",
            "refseq_ac": "NP_014271",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.67",
                    "type": "synonym"
                },
                {
                    "name": "putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "TEP1",
                    "type": "recommended"
                },
                {
                    "name": "N1220",
                    "type": "synonym"
                },
                {
                    "name": "N1872",
                    "type": "synonym"
                },
                {
                    "name": "TEP1",
                    "type": "synonym"
                }
            ],
            "record_id": "P53916-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q03790-1",
            "uniprot_ac": "Q03790",
            "uniprot_id": "NUP53_YEAST",
            "refseq_ac": "NP_013873",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Nucleoporin NUP53",
                    "type": "recommended"
                },
                {
                    "name": "FG-nucleoporin NUP53",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear pore protein NUP53",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "NUP53",
                    "type": "recommended"
                },
                {
                    "name": "NUP53",
                    "type": "synonym"
                },
                {
                    "name": "YM8520.02",
                    "type": "synonym"
                }
            ],
            "record_id": "Q03790-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O54857-1",
            "uniprot_ac": "O54857",
            "uniprot_id": "PTEN_RAT",
            "refseq_ac": "NP_113794",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.-",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.16",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.48",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.67",
                    "type": "synonym"
                },
                {
                    "name": "Inositol polyphosphate 3-phosphatase",
                    "type": "synonym"
                },
                {
                    "name": "Phosphatase and tensin homolog",
                    "type": "synonym"
                },
                {
                    "name": "inositol polyphosphate 3-phosphatase",
                    "type": "synonym"
                },
                {
                    "name": "mutated in multiple advanced cancers 1",
                    "type": "synonym"
                },
                {
                    "name": "phosphatase and tensin homolog deleted on chromosome ten",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                    "type": "synonym"
                },
                {
                    "name": "protein tyrosine phosphatase and tensin-like protein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pten",
                    "type": "recommended"
                },
                {
                    "name": "MMAC1",
                    "type": "synonym"
                },
                {
                    "name": "Mmac",
                    "type": "synonym"
                },
                {
                    "name": "Pten",
                    "type": "synonym"
                },
                {
                    "name": "TEP1",
                    "type": "synonym"
                },
                {
                    "name": "rCG_47874",
                    "type": "synonym"
                }
            ],
            "record_id": "O54857-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2JVZ2-1",
            "uniprot_ac": "A0A0G2JVZ2",
            "uniprot_id": "A0A0G2JVZ2_RAT",
            "refseq_ac": "NP_001165596",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "T-cell leukemia homeobox 2",
                    "type": "synonym"
                },
                {
                    "name": "T-cell leukemia homeobox protein 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Tlx2",
                    "type": "recommended"
                },
                {
                    "name": "Hox11L.1",
                    "type": "synonym"
                },
                {
                    "name": "Tlx2",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0G2JVZ2-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q68FY1-1",
            "uniprot_ac": "Q68FY1",
            "uniprot_id": "NUP35_RAT",
            "refseq_ac": "NP_001004229",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Nucleoporin NUP35",
                    "type": "recommended"
                },
                {
                    "name": "35 kDa nucleoporin",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear pore complex protein Nup53",
                    "type": "synonym"
                },
                {
                    "name": "Nucleoporin NUP53",
                    "type": "synonym"
                },
                {
                    "name": "mitotic phosphoprotein 44",
                    "type": "synonym"
                },
                {
                    "name": "nuclear pore complex protein Nup53",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin NUP35",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin NUP53",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Nup35",
                    "type": "recommended"
                },
                {
                    "name": "Nup35",
                    "type": "synonym"
                },
                {
                    "name": "Nup53",
                    "type": "synonym"
                }
            ],
            "record_id": "Q68FY1-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O44783-1",
            "uniprot_ac": "O44783",
            "uniprot_id": "SPY_DROME",
            "refseq_ac": "NP_523902",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein sprouty",
                    "type": "recommended"
                },
                {
                    "name": "CG1921-PB",
                    "type": "synonym"
                },
                {
                    "name": "Spry",
                    "type": "synonym"
                },
                {
                    "name": "calcineurin suppressor, chromosome 3, group 3",
                    "type": "synonym"
                },
                {
                    "name": "dSprouty",
                    "type": "synonym"
                },
                {
                    "name": "sprouty, isoform B",
                    "type": "synonym"
                },
                {
                    "name": "sprouty",
                    "type": "synonym"
                },
                {
                    "name": "sty-PB",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "sty",
                    "type": "recommended"
                },
                {
                    "name": "CG1921",
                    "type": "synonym"
                },
                {
                    "name": "CS3-3",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG1921",
                    "type": "synonym"
                },
                {
                    "name": "STY",
                    "type": "synonym"
                },
                {
                    "name": "Spry",
                    "type": "synonym"
                },
                {
                    "name": "Sry",
                    "type": "synonym"
                },
                {
                    "name": "Sty",
                    "type": "synonym"
                },
                {
                    "name": "dSPRY",
                    "type": "synonym"
                },
                {
                    "name": "spry",
                    "type": "synonym"
                },
                {
                    "name": "sty",
                    "type": "synonym"
                }
            ],
            "record_id": "O44783-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9VWS2-1",
            "uniprot_ac": "Q9VWS2",
            "uniprot_id": "NUP35_DROME",
            "refseq_ac": "NP_573314",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Nucleoporin Nup35",
                    "type": "recommended"
                },
                {
                    "name": "35 kDa nucleoporin",
                    "type": "synonym"
                },
                {
                    "name": "CG6540-PA",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear pore complex protein Nup35",
                    "type": "synonym"
                },
                {
                    "name": "Nucleoporin Nup53",
                    "type": "synonym"
                },
                {
                    "name": "Nup35-PA",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin 35kDa",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Nup35",
                    "type": "recommended"
                },
                {
                    "name": "CG6540",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG6540",
                    "type": "synonym"
                },
                {
                    "name": "Nup35",
                    "type": "synonym"
                },
                {
                    "name": "Nup53",
                    "type": "synonym"
                },
                {
                    "name": "nup35",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9VWS2-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q7KS72-1",
            "uniprot_ac": "Q7KS72",
            "uniprot_id": "Q7KS72_DROME",
            "refseq_ac": "NP_476873",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "C15-PA",
                    "type": "synonym"
                },
                {
                    "name": "C15",
                    "type": "synonym"
                },
                {
                    "name": "CG7937-PA",
                    "type": "synonym"
                },
                {
                    "name": "clawless",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "C15",
                    "type": "recommended"
                },
                {
                    "name": "311",
                    "type": "synonym"
                },
                {
                    "name": "93Bal",
                    "type": "synonym"
                },
                {
                    "name": "C15",
                    "type": "synonym"
                },
                {
                    "name": "CG7937",
                    "type": "synonym"
                },
                {
                    "name": "Cll",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG7937",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG7937",
                    "type": "synonym"
                },
                {
                    "name": "Ect5",
                    "type": "synonym"
                },
                {
                    "name": "Hox11-311",
                    "type": "synonym"
                },
                {
                    "name": "c15",
                    "type": "synonym"
                },
                {
                    "name": "cll",
                    "type": "synonym"
                }
            ],
            "record_id": "Q7KS72-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P60484-1",
            "uniprot_ac": "P60484",
            "uniprot_id": "PTEN_HUMAN",
            "refseq_ac": "NP_000305",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.-",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.16",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.48",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.67",
                    "type": "synonym"
                },
                {
                    "name": "Inositol polyphosphate 3-phosphatase",
                    "type": "synonym"
                },
                {
                    "name": "MMAC1 phosphatase and tensin homolog deleted on chromosome 10",
                    "type": "synonym"
                },
                {
                    "name": "Mutated in multiple advanced cancers 1",
                    "type": "synonym"
                },
                {
                    "name": "PTEN variant PTEN-K267Rfs*9",
                    "type": "synonym"
                },
                {
                    "name": "PTEN variant PTEN-L247*",
                    "type": "synonym"
                },
                {
                    "name": "PTEN variant PTEN-R234Afs*11",
                    "type": "synonym"
                },
                {
                    "name": "PTENepsilon",
                    "type": "synonym"
                },
                {
                    "name": "Phosphatase and tensin homolog",
                    "type": "synonym"
                },
                {
                    "name": "inositol polyphosphate 3-phosphatase",
                    "type": "synonym"
                },
                {
                    "name": "mitochondrial PTENalpha",
                    "type": "synonym"
                },
                {
                    "name": "mitochondrial phosphatase and tensin protein alpha",
                    "type": "synonym"
                },
                {
                    "name": "mutated in multiple advanced cancers 1",
                    "type": "synonym"
                },
                {
                    "name": "phosphatase and tensin-like protein",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                    "type": "synonym"
                },
                {
                    "name": "protein tyrosine phosphatase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "PTEN",
                    "type": "recommended"
                },
                {
                    "name": "10q23del",
                    "type": "synonym"
                },
                {
                    "name": "BZS",
                    "type": "synonym"
                },
                {
                    "name": "CWS1",
                    "type": "synonym"
                },
                {
                    "name": "DEC",
                    "type": "synonym"
                },
                {
                    "name": "GLM2",
                    "type": "synonym"
                },
                {
                    "name": "MHAM",
                    "type": "synonym"
                },
                {
                    "name": "MMAC1",
                    "type": "synonym"
                },
                {
                    "name": "PTEN1",
                    "type": "synonym"
                },
                {
                    "name": "PTENbeta",
                    "type": "synonym"
                },
                {
                    "name": "PTENgama",
                    "type": "synonym"
                },
                {
                    "name": "PTEN",
                    "type": "synonym"
                },
                {
                    "name": "TEP1",
                    "type": "synonym"
                }
            ],
            "record_id": "P60484-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O43597-1",
            "uniprot_ac": "O43597",
            "uniprot_id": "SPY2_HUMAN",
            "refseq_ac": "NP_001305465",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein sprouty homolog 2",
                    "type": "recommended"
                },
                {
                    "name": "Spry-2",
                    "type": "synonym"
                },
                {
                    "name": "protein sprouty homolog 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "SPRY2",
                    "type": "recommended"
                },
                {
                    "name": "IGAN3",
                    "type": "synonym"
                },
                {
                    "name": "SPRY2",
                    "type": "synonym"
                },
                {
                    "name": "hSPRY2",
                    "type": "synonym"
                }
            ],
            "record_id": "O43597-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O43763-1",
            "uniprot_ac": "O43763",
            "uniprot_id": "TLX2_HUMAN",
            "refseq_ac": "NP_057254",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "T-cell leukemia homeobox protein 2",
                    "type": "recommended"
                },
                {
                    "name": "Homeobox protein Hox-11L1",
                    "type": "synonym"
                },
                {
                    "name": "Neural crest homeobox protein",
                    "type": "synonym"
                },
                {
                    "name": "T-cell leukemia homeobox protein 2",
                    "type": "synonym"
                },
                {
                    "name": "homeo box 11-like 1",
                    "type": "synonym"
                },
                {
                    "name": "homeobox protein Hox-11L1",
                    "type": "synonym"
                },
                {
                    "name": "neural crest homeobox protein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "TLX2",
                    "type": "recommended"
                },
                {
                    "name": "HOX11L1",
                    "type": "synonym"
                },
                {
                    "name": "NCX",
                    "type": "synonym"
                },
                {
                    "name": "TLX2",
                    "type": "synonym"
                }
            ],
            "record_id": "O43763-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q8NFH5-1",
            "uniprot_ac": "Q8NFH5",
            "uniprot_id": "NUP35_HUMAN",
            "refseq_ac": "NP_001274513",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Nucleoporin NUP35",
                    "type": "recommended"
                },
                {
                    "name": "35 kDa nucleoporin",
                    "type": "synonym"
                },
                {
                    "name": "MP-44",
                    "type": "synonym"
                },
                {
                    "name": "Mitotic phosphoprotein 44",
                    "type": "synonym"
                },
                {
                    "name": "Nuclear pore complex protein Nup53",
                    "type": "synonym"
                },
                {
                    "name": "Nucleoporin NUP53",
                    "type": "synonym"
                },
                {
                    "name": "mitotic phosphoprotein 44",
                    "type": "synonym"
                },
                {
                    "name": "nuclear pore complex protein Nup53",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin 35kDa",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin NUP35 isoform b",
                    "type": "synonym"
                },
                {
                    "name": "nucleoporin NUP53",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "NUP35",
                    "type": "recommended"
                },
                {
                    "name": "MP-44",
                    "type": "synonym"
                },
                {
                    "name": "MP44",
                    "type": "synonym"
                },
                {
                    "name": "NP44",
                    "type": "synonym"
                },
                {
                    "name": "NUP35",
                    "type": "synonym"
                },
                {
                    "name": "NUP53",
                    "type": "synonym"
                }
            ],
            "record_id": "Q8NFH5-1",
            "evidence": [
                {
                    "id": "0080072",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080072"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0080072"
}
