{
    "disease_id": "DOID:0070598",
    "recommended_name": {
        "id": "DOID:0070598",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0070598",
        "name": "X-linked spermatogenic failure 7",
        "description": "A spermatogenic failure characterized by sperm with insufficient individualization, excessive residual cytoplasm, acrosome defects, and abnormalities of the head and flagella, resulting in significantly reduced sperm concentration and progressive motility, that has_material_basis_in hemizygous mutation in the CT55 gene on chromosome Xq26.3."
    },
    "synonyms": [
        {
            "id": "DOID:0070598",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070598",
            "name": "SPGFX7",
            "description": ""
        },
        {
            "id": "MONDO:0957202",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957202",
            "name": "spermatogenic failure, X-linked, 7",
            "description": ""
        },
        {
            "id": "MIM:301106",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/301106",
            "name": "Spermatogenic failure, X-linked, 7",
            "description": "Spermatogenic failure, X-linked, 7"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0070598"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0070598",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070598",
            "categories": []
        },
        {
            "id": "MONDO:0957202",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957202",
            "categories": []
        },
        {
            "id": "MIM:301106",
            "database": "MIM",
            "url": "https://www.omim.org/entry/301106",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q14BQ3-1",
            "uniprot_ac": "Q14BQ3",
            "uniprot_id": "CT55_MOUSE",
            "refseq_ac": "NP_083418",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Cancer/testis antigen 55",
                    "type": "recommended"
                },
                {
                    "name": "cancer/testis antigen 55",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ct55",
                    "type": "recommended"
                },
                {
                    "name": "4930502E18Rik",
                    "type": "synonym"
                },
                {
                    "name": "Ct55",
                    "type": "synonym"
                }
            ],
            "record_id": "Q14BQ3-1",
            "evidence": [
                {
                    "id": "0070598",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070598"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q8WUE5-1",
            "uniprot_ac": "Q8WUE5",
            "uniprot_id": "CT55_HUMAN",
            "refseq_ac": "NP_001026875",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Cancer/testis antigen 55",
                    "type": "recommended"
                },
                {
                    "name": "BRCA2-interacting protein",
                    "type": "synonym"
                },
                {
                    "name": "Tumor antigen BJ-HCC-20",
                    "type": "synonym"
                },
                {
                    "name": "cancer/testis antigen 55 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "tumor antigen BJ-HCC-20",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CT55",
                    "type": "recommended"
                },
                {
                    "name": "BJHCC20A",
                    "type": "synonym"
                },
                {
                    "name": "CT55",
                    "type": "synonym"
                },
                {
                    "name": "CXorf48",
                    "type": "synonym"
                },
                {
                    "name": "SPGFX7",
                    "type": "synonym"
                }
            ],
            "record_id": "Q8WUE5-1",
            "evidence": [
                {
                    "id": "301106",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/301106"
                },
                {
                    "id": "0070598",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070598"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2K9A4-1",
            "uniprot_ac": "A0A0G2K9A4",
            "uniprot_id": "A0A0G2K9A4_RAT",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "CT55",
                    "type": "recommended"
                }
            ],
            "gene_names": [
                {
                    "name": "LOC120099188",
                    "type": "recommended"
                },
                {
                    "name": "LOC120099189",
                    "type": "recommended"
                },
                {
                    "name": "LOC120099190",
                    "type": "recommended"
                },
                {
                    "name": "LOC120099287",
                    "type": "recommended"
                },
                {
                    "name": "Ct55l1",
                    "type": "synonym"
                },
                {
                    "name": "LOC120099188",
                    "type": "synonym"
                },
                {
                    "name": "LOC120099189",
                    "type": "synonym"
                },
                {
                    "name": "LOC120099190",
                    "type": "synonym"
                },
                {
                    "name": "LOC120099191",
                    "type": "synonym"
                },
                {
                    "name": "LOC120099287",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0G2K9A4-1",
            "evidence": [
                {
                    "id": "0070598",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070598"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2KBA6-1",
            "uniprot_ac": "A0A0G2KBA6",
            "uniprot_id": "A0A0G2KBA6_RAT",
            "refseq_ac": "XP_038956274",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "S1-like RNA binding domain-containing protein",
                    "type": "recommended"
                },
                {
                    "name": "cancer/testis antigen 55-like isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "LOC120099259",
                    "type": "recommended"
                },
                {
                    "name": "4933416I08Rikl",
                    "type": "synonym"
                },
                {
                    "name": "LOC100910451",
                    "type": "synonym"
                },
                {
                    "name": "LOC120099259",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0G2KBA6-1",
            "evidence": [
                {
                    "id": "0070598",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070598"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I5ZUT8-1",
            "uniprot_ac": "A0A8I5ZUT8",
            "uniprot_id": "A0A8I5ZUT8_RAT",
            "refseq_ac": "NP_001420273",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Cancer/testis antigen 55",
                    "type": "synonym"
                },
                {
                    "name": "cancer/testis antigen 55",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ct55",
                    "type": "recommended"
                },
                {
                    "name": "Ct55",
                    "type": "synonym"
                },
                {
                    "name": "RGD1560456",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8I5ZUT8-1",
            "evidence": [
                {
                    "id": "0070598",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070598"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I5ZL93-1",
            "uniprot_ac": "A0A8I5ZL93",
            "uniprot_id": "A0A8I5ZL93_RAT",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "CT55",
                    "type": "recommended"
                }
            ],
            "gene_names": [
                {
                    "name": "LOC120099191",
                    "type": "recommended"
                }
            ],
            "record_id": "A0A8I5ZL93-1",
            "evidence": [
                {
                    "id": "0070598",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070598"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0070598"
}