{
    "disease_id": "DOID:0070592",
    "recommended_name": {
        "id": "DOID:0070592",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0070592",
        "name": "spermatogenic failure 93",
        "description": "A spermatogenic failure characterized by nonosbtructive azoospermia or multiple morphologic abnormalities of the sperm flagella and markedly reduced progressive sperm motility that has_material_basis_in homozygous mutation in the STK33 gene on chromosome 11p15.4."
    },
    "synonyms": [
        {
            "id": "DOID:0070592",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070592",
            "name": "SPGF93",
            "description": ""
        },
        {
            "id": "MONDO:0971000",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0971000",
            "name": "spermatogenic failure 93",
            "description": ""
        },
        {
            "id": "MIM:620849",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/620849",
            "name": "Spermatogenic failure 93",
            "description": "Spermatogenic failure 93"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0070592"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0070592",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070592",
            "categories": []
        },
        {
            "id": "MONDO:0971000",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0971000",
            "categories": []
        },
        {
            "id": "MIM:620849",
            "database": "MIM",
            "url": "https://www.omim.org/entry/620849",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0AC58G011-1",
            "uniprot_ac": "A0AC58G011",
            "uniprot_id": "A0AC58G011_DANRE",
            "refseq_ac": "XP_073762978",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein kinase 33",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase 33 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "stk33",
                    "type": "recommended"
                },
                {
                    "name": "si:ch211-208c6.6",
                    "type": "synonym"
                },
                {
                    "name": "stk33",
                    "type": "synonym"
                },
                {
                    "name": "wu:fab03g11",
                    "type": "synonym"
                }
            ],
            "record_id": "A0AC58G011-1",
            "evidence": [
                {
                    "id": "0070592",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070592"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q924X7-1",
            "uniprot_ac": "Q924X7",
            "uniprot_id": "STK33_MOUSE",
            "refseq_ac": "NP_473444",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein kinase 33",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase 33 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase 33",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Stk33",
                    "type": "recommended"
                },
                {
                    "name": "4921505G21Rik",
                    "type": "synonym"
                },
                {
                    "name": "Stk33",
                    "type": "synonym"
                }
            ],
            "record_id": "Q924X7-1",
            "evidence": [
                {
                    "id": "0070592",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070592"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9BYT3-1",
            "uniprot_ac": "Q9BYT3",
            "uniprot_id": "STK33_HUMAN",
            "refseq_ac": "NP_001275987",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein kinase 33",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase 33 isoform b",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase 33",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "STK33",
                    "type": "recommended"
                },
                {
                    "name": "SPGF93",
                    "type": "synonym"
                },
                {
                    "name": "STK33",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9BYT3-1",
            "evidence": [
                {
                    "id": "620849",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/620849"
                },
                {
                    "id": "0070592",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070592"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "D4A165-1",
            "uniprot_ac": "D4A165",
            "uniprot_id": "D4A165_RAT",
            "refseq_ac": "NP_001419557",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein kinase 33",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase 33",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Stk33",
                    "type": "recommended"
                },
                {
                    "name": "Stk33",
                    "type": "synonym"
                }
            ],
            "record_id": "D4A165-1",
            "evidence": [
                {
                    "id": "0070592",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070592"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0070592"
}