{
    "disease_id": "DOID:0070581",
    "recommended_name": {
        "id": "DOID:0070581",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0070581",
        "name": "spermatogenic failure 82",
        "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the sperm flagella that has_material_basis_in homozygous mutation in the AKAP3 gene on chromosome 12p13.32."
    },
    "synonyms": [
        {
            "id": "DOID:0070581",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070581",
            "name": "SPGF82",
            "description": ""
        },
        {
            "id": "MONDO:0957249",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957249",
            "name": "spermatogenic failure 82",
            "description": ""
        },
        {
            "id": "MIM:620353",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/620353",
            "name": "Spermatogenic failure 82",
            "description": "Spermatogenic failure 82"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0070581"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0070581",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070581",
            "categories": []
        },
        {
            "id": "MONDO:0957249",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957249",
            "categories": []
        },
        {
            "id": "MIM:620353",
            "database": "MIM",
            "url": "https://www.omim.org/entry/620353",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "O88987-1",
            "uniprot_ac": "O88987",
            "uniprot_id": "AKAP3_MOUSE",
            "refseq_ac": "NP_033780",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "A-kinase anchor protein 3",
                    "type": "recommended"
                },
                {
                    "name": "A kinase (PRKA) anchor protein 3",
                    "type": "synonym"
                },
                {
                    "name": "A-kinase anchor protein 110 kDa",
                    "type": "synonym"
                },
                {
                    "name": "A-kinase anchor protein 3",
                    "type": "synonym"
                },
                {
                    "name": "AKAP 110",
                    "type": "synonym"
                },
                {
                    "name": "AKAP-3",
                    "type": "synonym"
                },
                {
                    "name": "PRKA3",
                    "type": "synonym"
                },
                {
                    "name": "Protein kinase A-anchoring protein 3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Akap3",
                    "type": "recommended"
                },
                {
                    "name": "Akap110",
                    "type": "synonym"
                },
                {
                    "name": "Akap3",
                    "type": "synonym"
                },
                {
                    "name": "Prka3",
                    "type": "synonym"
                }
            ],
            "record_id": "O88987-1",
            "evidence": [
                {
                    "id": "0070581",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070581"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O75969-1",
            "uniprot_ac": "O75969",
            "uniprot_id": "AKAP3_HUMAN",
            "refseq_ac": "NP_001265238",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "A-kinase anchor protein 3",
                    "type": "recommended"
                },
                {
                    "name": "A kinase (PRKA) anchor protein 3",
                    "type": "synonym"
                },
                {
                    "name": "A-kinase anchor protein 110 kDa",
                    "type": "synonym"
                },
                {
                    "name": "A-kinase anchor protein 3",
                    "type": "synonym"
                },
                {
                    "name": "A-kinase anchor protein, 110kDa",
                    "type": "synonym"
                },
                {
                    "name": "AKAP 110",
                    "type": "synonym"
                },
                {
                    "name": "AKAP-3",
                    "type": "synonym"
                },
                {
                    "name": "CT82",
                    "type": "synonym"
                },
                {
                    "name": "Cancer/testis antigen 82",
                    "type": "synonym"
                },
                {
                    "name": "FSP95",
                    "type": "synonym"
                },
                {
                    "name": "Fibrous Sheath Protein of 95 kDa",
                    "type": "synonym"
                },
                {
                    "name": "Fibrous sheath protein of 95 kDa",
                    "type": "synonym"
                },
                {
                    "name": "Fibrousheathin I",
                    "type": "synonym"
                },
                {
                    "name": "Fibrousheathin-1",
                    "type": "synonym"
                },
                {
                    "name": "PRKA3",
                    "type": "synonym"
                },
                {
                    "name": "Protein kinase A-anchoring protein 3",
                    "type": "synonym"
                },
                {
                    "name": "Sperm oocyte-binding protein",
                    "type": "synonym"
                },
                {
                    "name": "cancer/testis antigen 82",
                    "type": "synonym"
                },
                {
                    "name": "epididymis luminal protein 159",
                    "type": "synonym"
                },
                {
                    "name": "epididymis secretory sperm binding protein",
                    "type": "synonym"
                },
                {
                    "name": "fibrousheathin I",
                    "type": "synonym"
                },
                {
                    "name": "fibrousheathin-1",
                    "type": "synonym"
                },
                {
                    "name": "protein kinase A binding protein AKAP 110",
                    "type": "synonym"
                },
                {
                    "name": "protein kinase A-anchoring protein 3",
                    "type": "synonym"
                },
                {
                    "name": "sperm oocyte-binding protein 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "AKAP3",
                    "type": "recommended"
                },
                {
                    "name": "AKAP 110",
                    "type": "synonym"
                },
                {
                    "name": "AKAP110",
                    "type": "synonym"
                },
                {
                    "name": "AKAP3",
                    "type": "synonym"
                },
                {
                    "name": "CT82",
                    "type": "synonym"
                },
                {
                    "name": "FSP95",
                    "type": "synonym"
                },
                {
                    "name": "HEL159",
                    "type": "synonym"
                },
                {
                    "name": "PRKA3",
                    "type": "synonym"
                },
                {
                    "name": "SOB1",
                    "type": "synonym"
                },
                {
                    "name": "SPGF82",
                    "type": "synonym"
                }
            ],
            "record_id": "O75969-1",
            "evidence": [
                {
                    "id": "620353",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/620353"
                },
                {
                    "id": "0070581",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070581"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q66HC6-1",
            "uniprot_ac": "Q66HC6",
            "uniprot_id": "Q66HC6_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "A-kinase anchoring protein 3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Akap3",
                    "type": "recommended"
                }
            ],
            "record_id": "Q66HC6-1",
            "evidence": [
                {
                    "id": "0070581",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070581"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0070581"
}