{
    "disease_id": "DOID:0070080",
    "recommended_name": {
        "id": "DOID:0070080",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0070080",
        "name": "schizophrenia 4",
        "description": "A schizophrenia that has_material_basis_in an autosomal dominant mutation of the PRODH gene on chromosome 22q11.21."
    },
    "synonyms": [
        {
            "id": "DOID:0070080",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070080",
            "name": "SCZD4",
            "description": ""
        },
        {
            "id": "MONDO:0010943",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010943",
            "name": "schizophrenia 4",
            "description": "A schizophrenia that has material basis in an autosomal dominant mutation of PRODH on chromosome 22q11.21."
        },
        {
            "id": "MONDO:0010943",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010943",
            "name": "SCZD4",
            "description": ""
        },
        {
            "id": "MONDO:0010943",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010943",
            "name": "schizophrenia 4",
            "description": ""
        },
        {
            "id": "MONDO:0010943",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010943",
            "name": "schizophrenia type 4",
            "description": ""
        },
        {
            "id": "MONDO:0010943",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010943",
            "name": "schizophrenia, susceptibility to, 4",
            "description": ""
        },
        {
            "id": "MIM:600850",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/600850",
            "name": "Schizophrenia 4",
            "description": "Schizophrenia 4"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0070080"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0070080",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070080",
            "categories": []
        },
        {
            "id": "MONDO:0010943",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010943",
            "categories": []
        },
        {
            "id": "MIM:600850",
            "database": "MIM",
            "url": "https://www.omim.org/entry/600850",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8M1RHY4-1",
            "uniprot_ac": "A0A8M1RHY4",
            "uniprot_id": "A0A8M1RHY4_DANRE",
            "refseq_ac": "XP_002665916",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Proline dehydrogenase",
                    "type": "recommended"
                },
                {
                    "name": "1.5.5.2",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase 1, mitochondrial isoform X2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "prodha",
                    "type": "recommended"
                },
                {
                    "name": "prodha",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M1RHY4-1",
            "evidence": [
                {
                    "id": "0070080",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070080"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9WU79-1",
            "uniprot_ac": "Q9WU79",
            "uniprot_id": "PROD_MOUSE",
            "refseq_ac": "NP_035302",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Proline dehydrogenase 1, mitochondrial",
                    "type": "recommended"
                },
                {
                    "name": "1.5.5.2",
                    "type": "synonym"
                },
                {
                    "name": "Proline oxidase",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase 1, mitochondrial precursor",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase 1, mitochondrial",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase, mitochondrial",
                    "type": "synonym"
                },
                {
                    "name": "proline oxidase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Prodh",
                    "type": "recommended"
                },
                {
                    "name": "Pro-1",
                    "type": "synonym"
                },
                {
                    "name": "Pro1",
                    "type": "synonym"
                },
                {
                    "name": "Prodh",
                    "type": "synonym"
                },
                {
                    "name": "Ym24d07",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9WU79-1",
            "evidence": [
                {
                    "id": "0070080",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070080"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O43272-4",
            "uniprot_ac": "O43272",
            "uniprot_id": "PROD_HUMAN",
            "refseq_ac": "NP_001182155",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Proline dehydrogenase 1, mitochondrial",
                    "type": "recommended"
                },
                {
                    "name": "1.5.5.2",
                    "type": "synonym"
                },
                {
                    "name": "Proline oxidase 2",
                    "type": "synonym"
                },
                {
                    "name": "Proline oxidase",
                    "type": "synonym"
                },
                {
                    "name": "p53 Inducible gene 6",
                    "type": "synonym"
                },
                {
                    "name": "p53-induced gene 6 protein",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase (oxidase) 1",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase 1, mitochondrial isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase 1, mitochondrial",
                    "type": "synonym"
                },
                {
                    "name": "proline oxidase 2",
                    "type": "synonym"
                },
                {
                    "name": "proline oxidase, mitochondrial",
                    "type": "synonym"
                },
                {
                    "name": "tumor protein p53 inducible protein 6",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "PRODH",
                    "type": "recommended"
                },
                {
                    "name": "HSPOX2",
                    "type": "synonym"
                },
                {
                    "name": "PIG6",
                    "type": "synonym"
                },
                {
                    "name": "POX2",
                    "type": "synonym"
                },
                {
                    "name": "POX",
                    "type": "synonym"
                },
                {
                    "name": "PRODH1",
                    "type": "synonym"
                },
                {
                    "name": "PRODH2",
                    "type": "synonym"
                },
                {
                    "name": "PRODH",
                    "type": "synonym"
                },
                {
                    "name": "TP53I6",
                    "type": "synonym"
                }
            ],
            "record_id": "O43272-4",
            "evidence": [
                {
                    "id": "600850",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/600850"
                },
                {
                    "id": "0070080",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070080"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P09368-1",
            "uniprot_ac": "P09368",
            "uniprot_id": "PUT1_YEAST",
            "refseq_ac": "NP_013243",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Proline dehydrogenase, mitochondrial",
                    "type": "recommended"
                },
                {
                    "name": "1.5.5.2",
                    "type": "synonym"
                },
                {
                    "name": "Proline oxidase",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "PUT1",
                    "type": "recommended"
                },
                {
                    "name": "L3170",
                    "type": "synonym"
                },
                {
                    "name": "L9606.2",
                    "type": "synonym"
                },
                {
                    "name": "PUT1",
                    "type": "synonym"
                }
            ],
            "record_id": "P09368-1",
            "evidence": [
                {
                    "id": "0070080",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070080"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "F1MAR6-1",
            "uniprot_ac": "F1MAR6",
            "uniprot_id": "F1MAR6_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Proline dehydrogenase",
                    "type": "recommended"
                },
                {
                    "name": "1.5.5.2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Prodh1",
                    "type": "recommended"
                },
                {
                    "name": "Prodh",
                    "type": "synonym"
                }
            ],
            "record_id": "F1MAR6-1",
            "evidence": [
                {
                    "id": "0070080",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070080"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q04499-1",
            "uniprot_ac": "Q04499",
            "uniprot_id": "PROD_DROME",
            "refseq_ac": "NP_001245791",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Proline dehydrogenase 1, mitochondrial",
                    "type": "recommended"
                },
                {
                    "name": "1.5.5.2",
                    "type": "synonym"
                },
                {
                    "name": "CG1417-PI",
                    "type": "synonym"
                },
                {
                    "name": "Proline oxidase",
                    "type": "synonym"
                },
                {
                    "name": "Protein sluggish-A",
                    "type": "synonym"
                },
                {
                    "name": "proline dehydrogenase",
                    "type": "synonym"
                },
                {
                    "name": "slgA-PI",
                    "type": "synonym"
                },
                {
                    "name": "sluggish A, isoform I",
                    "type": "synonym"
                },
                {
                    "name": "sluggish-A",
                    "type": "synonym"
                },
                {
                    "name": "sluggishA",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "slgA",
                    "type": "recommended"
                },
                {
                    "name": "CG1417",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG1417",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG1417",
                    "type": "synonym"
                },
                {
                    "name": "EE85",
                    "type": "synonym"
                },
                {
                    "name": "PRODH",
                    "type": "synonym"
                },
                {
                    "name": "slgA",
                    "type": "synonym"
                },
                {
                    "name": "slg",
                    "type": "synonym"
                },
                {
                    "name": "sl",
                    "type": "synonym"
                },
                {
                    "name": "tu3",
                    "type": "synonym"
                }
            ],
            "record_id": "Q04499-1",
            "evidence": [
                {
                    "id": "0070080",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070080"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0070080"
}