{
    "disease_id": "DOID:0061194",
    "recommended_name": {
        "id": "DOID:0061194",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0061194",
        "name": "nephrotic syndrome type 24",
        "description": "A familial nephrotic syndrome characterized by onset of proteinuria and hypoalbuminemia in early childhood, although onset in the second decade has been reported. that has_material_basis_in homozygous or compound heterozygous mutation in the DAAM2 gene on chromosome 6p21."
    },
    "synonyms": [
        {
            "id": "DOID:0061194",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0061194",
            "name": "NPHS24",
            "description": ""
        },
        {
            "id": "MONDO:0031008",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0031008",
            "name": "nephrotic syndrome, type 24",
            "description": ""
        },
        {
            "id": "MONDO:0031008",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0031008",
            "name": "NPHS24",
            "description": ""
        },
        {
            "id": "MONDO:0031008",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0031008",
            "name": "idiopathic SRNS",
            "description": ""
        },
        {
            "id": "MONDO:0031008",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0031008",
            "name": "idiopathic steroid-resistant nephrotic syndrome",
            "description": ""
        },
        {
            "id": "MIM:619263",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/619263",
            "name": "Nephrotic syndrome 24",
            "description": "Nephrotic syndrome 24"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0061194"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0061194",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0061194",
            "categories": []
        },
        {
            "id": "MONDO:0031008",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0031008",
            "categories": []
        },
        {
            "id": "MIM:619263",
            "database": "MIM",
            "url": "https://www.omim.org/entry/619263",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0AC58HP70-1",
            "uniprot_ac": "A0AC58HP70",
            "uniprot_id": "A0AC58HP70_DANRE",
            "refseq_ac": "XP_073783764",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Disheveled-associated activator of morphogenesis 2 isoform X1",
                    "type": "synonym"
                },
                {
                    "name": "disheveled-associated activator of morphogenesis 2 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "daam2",
                    "type": "recommended"
                },
                {
                    "name": "daam2",
                    "type": "synonym"
                }
            ],
            "record_id": "A0AC58HP70-1",
            "evidence": [
                {
                    "id": "0061194",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0061194"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q80U19-1",
            "uniprot_ac": "Q80U19",
            "uniprot_id": "DAAM2_MOUSE",
            "refseq_ac": "NP_001008232",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Disheveled-associated activator of morphogenesis 2",
                    "type": "recommended"
                },
                {
                    "name": "disheveled-associated activator of morphogenesis 2 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "disheveled-associated activator of morphogenesis 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Daam2",
                    "type": "recommended"
                },
                {
                    "name": "2310016D11Rik",
                    "type": "synonym"
                },
                {
                    "name": "Daam2",
                    "type": "synonym"
                },
                {
                    "name": "Kiaa0381",
                    "type": "synonym"
                }
            ],
            "record_id": "Q80U19-1",
            "evidence": [
                {
                    "id": "0061194",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0061194"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q86T65-3",
            "uniprot_ac": "Q86T65",
            "uniprot_id": "DAAM2_HUMAN",
            "refseq_ac": "NP_001188356",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Disheveled-associated activator of morphogenesis 2",
                    "type": "recommended"
                },
                {
                    "name": "disheveled-associated activator of morphogenesis 2 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "disheveled-associated activator of morphogenesis 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "DAAM2",
                    "type": "recommended"
                },
                {
                    "name": "DAAM2",
                    "type": "synonym"
                },
                {
                    "name": "KIAA0381",
                    "type": "synonym"
                },
                {
                    "name": "NPHS24",
                    "type": "synonym"
                },
                {
                    "name": "dJ90A20A.1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q86T65-3",
            "evidence": [
                {
                    "id": "619263",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/619263"
                },
                {
                    "id": "0061194",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0061194"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P41832-1",
            "uniprot_ac": "P41832",
            "uniprot_id": "BNI1_YEAST",
            "refseq_ac": "NP_014128",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein BNI1",
                    "type": "recommended"
                },
                {
                    "name": "Pointed projection formation protein 3",
                    "type": "synonym"
                },
                {
                    "name": "Sensitive to high expression protein 5",
                    "type": "synonym"
                },
                {
                    "name": "Synthetic lethal 39",
                    "type": "synonym"
                },
                {
                    "name": "formin BNI1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "BNI1",
                    "type": "recommended"
                },
                {
                    "name": "BNI1",
                    "type": "synonym"
                },
                {
                    "name": "N0646",
                    "type": "synonym"
                },
                {
                    "name": "PPF3",
                    "type": "synonym"
                },
                {
                    "name": "SHE5",
                    "type": "synonym"
                }
            ],
            "record_id": "P41832-1",
            "evidence": [
                {
                    "id": "0061194",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0061194"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I6B158-1",
            "uniprot_ac": "A0A8I6B158",
            "uniprot_id": "A0A8I6B158_RAT",
            "refseq_ac": "NP_001414578",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Dishevelled associated activator of morphogenesis 2",
                    "type": "synonym"
                },
                {
                    "name": "disheveled-associated activator of morphogenesis 2-like",
                    "type": "synonym"
                },
                {
                    "name": "disheveled-associated activator of morphogenesis 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Daam2",
                    "type": "recommended"
                },
                {
                    "name": "Daam2",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8I6B158-1",
            "evidence": [
                {
                    "id": "0061194",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0061194"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "M9MSM5-1",
            "uniprot_ac": "M9MSM5",
            "uniprot_id": "M9MSM5_DROME",
            "refseq_ac": "NP_001188522",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "CG14622-PD",
                    "type": "synonym"
                },
                {
                    "name": "DAAM-PD",
                    "type": "synonym"
                },
                {
                    "name": "DIA-like",
                    "type": "synonym"
                },
                {
                    "name": "Dishevelled associated activator of morphogenesis, isoform D",
                    "type": "synonym"
                },
                {
                    "name": "dishevelled associated activator of morphogenesis, isoform D",
                    "type": "synonym"
                },
                {
                    "name": "dishevelled associated activator of morphogenesis",
                    "type": "synonym"
                },
                {
                    "name": "formin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "DAAM",
                    "type": "recommended"
                },
                {
                    "name": "CG14622",
                    "type": "synonym"
                },
                {
                    "name": "DAAM1",
                    "type": "synonym"
                },
                {
                    "name": "DAAM",
                    "type": "synonym"
                },
                {
                    "name": "Daam1",
                    "type": "synonym"
                },
                {
                    "name": "Daam",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG14622",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG14622",
                    "type": "synonym"
                },
                {
                    "name": "EG:114D9.2",
                    "type": "synonym"
                },
                {
                    "name": "anon-EST:Posey148",
                    "type": "synonym"
                },
                {
                    "name": "dDAAM",
                    "type": "synonym"
                },
                {
                    "name": "dDaam",
                    "type": "synonym"
                },
                {
                    "name": "daam1",
                    "type": "synonym"
                },
                {
                    "name": "daam",
                    "type": "synonym"
                }
            ],
            "record_id": "M9MSM5-1",
            "evidence": [
                {
                    "id": "0061194",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0061194"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0061194"
}