{
    "disease_id": "DOID:0060897",
    "recommended_name": {
        "id": "DOID:0060897",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060897",
        "name": "Parkinson's disease 17",
        "description": "A late-onset Parkinson disease that has_material_basis_in heterozygous mutation in the VPS35 gene on chromosome 16q13."
    },
    "synonyms": [
        {
            "id": "DOID:0060897",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060897",
            "name": "Parkinson disease 17",
            "description": ""
        },
        {
            "id": "DOID:0060897",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060897",
            "name": "autosomal dominant Parkinson disease 17",
            "description": ""
        },
        {
            "id": "MONDO:0013625",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013625",
            "name": "Parkinson disease 17",
            "description": "Any Parkinson disease in which the cause of the disease is a mutation in the VPS35 gene."
        },
        {
            "id": "MONDO:0013625",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013625",
            "name": "Parkinson disease 17",
            "description": ""
        },
        {
            "id": "MONDO:0013625",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013625",
            "name": "Parkinson disease caused by mutation in VPS35",
            "description": ""
        },
        {
            "id": "MONDO:0013625",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013625",
            "name": "Parkinson disease type 17",
            "description": ""
        },
        {
            "id": "MONDO:0013625",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013625",
            "name": "VPS35 Parkinson disease",
            "description": ""
        },
        {
            "id": "MONDO:0013625",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013625",
            "name": "PARK17",
            "description": ""
        },
        {
            "id": "MIM:614203",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/614203",
            "name": "Parkinson disease 17",
            "description": "Parkinson disease 17"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0060897"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0060897",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060897",
            "categories": []
        },
        {
            "id": "MONDO:0013625",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013625",
            "categories": []
        },
        {
            "id": "MIM:614203",
            "database": "MIM",
            "url": "https://www.omim.org/entry/614203",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q6ZM34-1",
            "uniprot_ac": "Q6ZM34",
            "uniprot_id": "Q6ZM34_DANRE",
            "refseq_ac": "NP_001020688",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Vacuolar protein sorting-associated protein 35",
                    "type": "recommended"
                },
                {
                    "name": "vacuolar protein sorting 35 homolog",
                    "type": "synonym"
                },
                {
                    "name": "vacuolar protein sorting-associated protein 35",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "vps35",
                    "type": "recommended"
                },
                {
                    "name": "bZ34G2.3",
                    "type": "synonym"
                },
                {
                    "name": "si:rp71-34g2.3",
                    "type": "synonym"
                },
                {
                    "name": "vps35",
                    "type": "synonym"
                },
                {
                    "name": "wu:fa66e03",
                    "type": "synonym"
                },
                {
                    "name": "wu:fb95c08",
                    "type": "synonym"
                },
                {
                    "name": "zgc:136268",
                    "type": "synonym"
                }
            ],
            "record_id": "Q6ZM34-1",
            "evidence": [
                {
                    "id": "0060897",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060897"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9EQH3-1",
            "uniprot_ac": "Q9EQH3",
            "uniprot_id": "VPS35_MOUSE",
            "refseq_ac": "NP_075373",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Vacuolar protein sorting-associated protein 35",
                    "type": "recommended"
                },
                {
                    "name": "Maternal-embryonic 3",
                    "type": "synonym"
                },
                {
                    "name": "Vesicle protein sorting 35",
                    "type": "synonym"
                },
                {
                    "name": "maternal embryonic message 3",
                    "type": "synonym"
                },
                {
                    "name": "vacuolar protein sorting-associated protein 35",
                    "type": "synonym"
                },
                {
                    "name": "vesicle protein sorting 35",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Vps35",
                    "type": "recommended"
                },
                {
                    "name": "Mem3",
                    "type": "synonym"
                },
                {
                    "name": "Vps35",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9EQH3-1",
            "evidence": [
                {
                    "id": "0060897",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060897"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q96QK1-1",
            "uniprot_ac": "Q96QK1",
            "uniprot_id": "VPS35_HUMAN",
            "refseq_ac": "NP_060676",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Vacuolar protein sorting-associated protein 35",
                    "type": "recommended"
                },
                {
                    "name": "Maternal-embryonic 3",
                    "type": "synonym"
                },
                {
                    "name": "Vesicle protein sorting 35",
                    "type": "synonym"
                },
                {
                    "name": "hVPS35",
                    "type": "synonym"
                },
                {
                    "name": "maternal-embryonic 3",
                    "type": "synonym"
                },
                {
                    "name": "vacuolar protein sorting 35 homolog",
                    "type": "synonym"
                },
                {
                    "name": "vacuolar protein sorting-associated protein 35",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "VPS35",
                    "type": "recommended"
                },
                {
                    "name": "MEM3",
                    "type": "synonym"
                },
                {
                    "name": "PARK17",
                    "type": "synonym"
                },
                {
                    "name": "TCCCTA00141",
                    "type": "synonym"
                },
                {
                    "name": "VPS35",
                    "type": "synonym"
                }
            ],
            "record_id": "Q96QK1-1",
            "evidence": [
                {
                    "id": "614203",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/614203"
                },
                {
                    "id": "0060897",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060897"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P34110-1",
            "uniprot_ac": "P34110",
            "uniprot_id": "VPS35_YEAST",
            "refseq_ac": "NP_012381",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Vacuolar protein sorting-associated protein 35",
                    "type": "recommended"
                },
                {
                    "name": "Vacuolar protein-targeting protein 7",
                    "type": "synonym"
                },
                {
                    "name": "retromer subunit VPS35",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "VPS35",
                    "type": "recommended"
                },
                {
                    "name": "ENV1",
                    "type": "synonym"
                },
                {
                    "name": "GRD9",
                    "type": "synonym"
                },
                {
                    "name": "J0580",
                    "type": "synonym"
                },
                {
                    "name": "VPS35",
                    "type": "synonym"
                },
                {
                    "name": "VPT7",
                    "type": "synonym"
                }
            ],
            "record_id": "P34110-1",
            "evidence": [
                {
                    "id": "0060897",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060897"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I6AI89-1",
            "uniprot_ac": "A0A8I6AI89",
            "uniprot_id": "A0A8I6AI89_RAT",
            "refseq_ac": "NP_001099188",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Vacuolar protein sorting-associated protein 35",
                    "type": "recommended"
                },
                {
                    "name": "Maternal embryonic message 3",
                    "type": "synonym"
                },
                {
                    "name": "vacuolar protein sorting 35 homolog",
                    "type": "synonym"
                },
                {
                    "name": "vacuolar protein sorting-associated protein 35",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Vps35",
                    "type": "recommended"
                },
                {
                    "name": "Mem3",
                    "type": "synonym"
                },
                {
                    "name": "Vps35",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8I6AI89-1",
            "evidence": [
                {
                    "id": "0060897",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060897"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9W277-1",
            "uniprot_ac": "Q9W277",
            "uniprot_id": "Q9W277_DROME",
            "refseq_ac": "NP_726175",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Vacuolar protein sorting-associated protein 35",
                    "type": "recommended"
                },
                {
                    "name": "CG5625-PB",
                    "type": "synonym"
                },
                {
                    "name": "Vps35-PB",
                    "type": "synonym"
                },
                {
                    "name": "vacuolar protein sorting 35, isoform B",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Vps35",
                    "type": "recommended"
                },
                {
                    "name": "CG5625",
                    "type": "synonym"
                },
                {
                    "name": "DVps35",
                    "type": "synonym"
                },
                {
                    "name": "DmVps35",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG5625",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG5625",
                    "type": "synonym"
                },
                {
                    "name": "Dvps35",
                    "type": "synonym"
                },
                {
                    "name": "VPS35",
                    "type": "synonym"
                },
                {
                    "name": "Vps35",
                    "type": "synonym"
                },
                {
                    "name": "dVPS35",
                    "type": "synonym"
                },
                {
                    "name": "dvps35",
                    "type": "synonym"
                },
                {
                    "name": "vps35",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9W277-1",
            "evidence": [
                {
                    "id": "0060897",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060897"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0060897"
}