{
    "disease_id": "DOID:0060809",
    "recommended_name": {
        "id": "DOID:0060809",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060809",
        "name": "syndromic X-linked intellectual disability Claes-Jensen type",
        "description": "A syndromic X-linked intellectual disability characterized by severe intellectual deficit associated with variable clinical manifestations including spasticity, cryptorchidism, maxillary hypoplasia, alopecia areata, epilepsy, short stature, impaired speech and behavioral problems that has_material_basis_in mutation in the KDM5C gene on chromosome Xp11."
    },
    "synonyms": [
        {
            "id": "DOID:0060809",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060809",
            "name": "MRXSCJ",
            "description": ""
        },
        {
            "id": "DOID:0060809",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060809",
            "name": "MRXSJ",
            "description": ""
        },
        {
            "id": "DOID:0060809",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060809",
            "name": "syndromic X-linked intellectual disability due to JARID1C mutation",
            "description": ""
        },
        {
            "id": "DOID:0060809",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060809",
            "name": "syndromic X-linked mental retardation JARID1C-related",
            "description": ""
        },
        {
            "id": "DOID:0060809",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060809",
            "name": "mental retardation, X-linked, syndromic, Claes-Jensen type",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "syndromic X-linked intellectual disability Claes-Jensen type",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "MRXSCJ",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "MRXSJ",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "intellectual developmental disorder, X-linked syndromic, Claes-Jensen type, X-linked recessive",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "intellectual disability, X-linked, syndromic, Claes-Jensen type",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "mental retardation, X-linked, syndromic, Claes-Jensen type",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "syndromic X-linked intellectual disability Claes-Jensen type",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "syndromic X-linked intellectual disability JARID1C-related",
            "description": ""
        },
        {
            "id": "MONDO:0010355",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "name": "mental retardation, X-linked, syndromic, JARID1C-related",
            "description": ""
        },
        {
            "id": "MIM:300534",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/300534",
            "name": "Intellectual developmental disorder, X-linked, syndromic, Claes-Jensen type",
            "description": "Intellectual developmental disorder, X-linked, syndromic, Claes-Jensen type"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0060809"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0060809",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060809",
            "categories": []
        },
        {
            "id": "MONDO:0010355",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0010355",
            "categories": []
        },
        {
            "id": "MIM:300534",
            "database": "MIM",
            "url": "https://www.omim.org/entry/300534",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "B0S6L0-1",
            "uniprot_ac": "B0S6L0",
            "uniprot_id": "B0S6L0_DANRE",
            "refseq_ac": "NP_001116706",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5D",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1D",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1D",
                    "type": "synonym"
                },
                {
                    "name": "Protein SmcY",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5D",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "smcx",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "kdm5c",
                    "type": "recommended"
                },
                {
                    "name": "im:7158173",
                    "type": "synonym"
                },
                {
                    "name": "jarid1c",
                    "type": "synonym"
                },
                {
                    "name": "kdm5c",
                    "type": "synonym"
                },
                {
                    "name": "si:ch211-218o21.2",
                    "type": "synonym"
                },
                {
                    "name": "wu:fa28h03",
                    "type": "synonym"
                },
                {
                    "name": "wu:fi31b07",
                    "type": "synonym"
                }
            ],
            "record_id": "B0S6L0-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q6IQX0-1",
            "uniprot_ac": "Q6IQX0",
            "uniprot_id": "KD5BB_DANRE",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5B-B",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1B-B",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1B-B",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5B-B",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "kdm5bb",
                    "type": "recommended"
                },
                {
                    "name": "cb264",
                    "type": "synonym"
                },
                {
                    "name": "jarid1bb",
                    "type": "synonym"
                },
                {
                    "name": "jarid1b",
                    "type": "synonym"
                },
                {
                    "name": "plu1",
                    "type": "synonym"
                },
                {
                    "name": "si:dkey-193l3.2",
                    "type": "synonym"
                },
                {
                    "name": "wu:fc44h11",
                    "type": "synonym"
                },
                {
                    "name": "zgc:85741",
                    "type": "synonym"
                }
            ],
            "record_id": "Q6IQX0-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8M9Q713-1",
            "uniprot_ac": "A0A8M9Q713",
            "uniprot_id": "A0A8M9Q713_DANRE",
            "refseq_ac": "NP_001334536",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "jumonji, AT rich interactive domain 1B (Rbp2 like)",
                    "type": "synonym"
                },
                {
                    "name": "jumonji, AT rich interactive domain 1Ba (Rbp2 like)",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5Ba",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "kdm5ba",
                    "type": "recommended"
                },
                {
                    "name": "id:ibd5050",
                    "type": "synonym"
                },
                {
                    "name": "jarid1ba",
                    "type": "synonym"
                },
                {
                    "name": "jarid1b",
                    "type": "synonym"
                },
                {
                    "name": "kdm5ba",
                    "type": "synonym"
                },
                {
                    "name": "wu:fd15c05",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M9Q713-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P41230-1",
            "uniprot_ac": "P41230",
            "uniprot_id": "KDM5C_MOUSE",
            "refseq_ac": "NP_038696",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5C",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1C",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1C",
                    "type": "synonym"
                },
                {
                    "name": "Protein SmcX",
                    "type": "synonym"
                },
                {
                    "name": "Protein Xe169",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase JARID1C",
                    "type": "synonym"
                },
                {
                    "name": "jumonji, AT rich interactive domain 1C (Rbp2 like)",
                    "type": "synonym"
                },
                {
                    "name": "jumonji/ARID domain-containing protein 1C",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5C isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "selected mouse cDNA on the X",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5c",
                    "type": "recommended"
                },
                {
                    "name": "D930009K15Rik",
                    "type": "synonym"
                },
                {
                    "name": "Jarid1c",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5c",
                    "type": "synonym"
                },
                {
                    "name": "Kiaa0234",
                    "type": "synonym"
                },
                {
                    "name": "Smcx",
                    "type": "synonym"
                },
                {
                    "name": "Xe169",
                    "type": "synonym"
                },
                {
                    "name": "mKIAA0234",
                    "type": "synonym"
                }
            ],
            "record_id": "P41230-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q3UXZ9-1",
            "uniprot_ac": "Q3UXZ9",
            "uniprot_id": "KDM5A_MOUSE",
            "refseq_ac": "NP_666109",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5A",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1A",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1A",
                    "type": "synonym"
                },
                {
                    "name": "RBBP-2",
                    "type": "synonym"
                },
                {
                    "name": "Retinoblastoma-binding protein 2",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5A",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase JARID1A",
                    "type": "synonym"
                },
                {
                    "name": "jumonji, AT rich interactive domain 1A (Rbp2 like)",
                    "type": "synonym"
                },
                {
                    "name": "jumonji/ARID domain-containing protein 1A",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5A",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5A",
                    "type": "synonym"
                },
                {
                    "name": "retinoblastoma binding protein 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5a",
                    "type": "recommended"
                },
                {
                    "name": "Jarid1a",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5a",
                    "type": "synonym"
                },
                {
                    "name": "RBP2",
                    "type": "synonym"
                },
                {
                    "name": "Rbbp2",
                    "type": "synonym"
                },
                {
                    "name": "Rbp2",
                    "type": "synonym"
                }
            ],
            "record_id": "Q3UXZ9-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q62240-1",
            "uniprot_ac": "Q62240",
            "uniprot_id": "KDM5D_MOUSE",
            "refseq_ac": "NP_035549",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5D",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "H-Y",
                    "type": "synonym"
                },
                {
                    "name": "Histocompatibility Y antigen",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1D",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1D",
                    "type": "synonym"
                },
                {
                    "name": "Protein SmcY",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5D",
                    "type": "synonym"
                },
                {
                    "name": "histocompatibility Y antigen",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase JARID1D",
                    "type": "synonym"
                },
                {
                    "name": "jumonji, AT rich interactive domain 1D (Rbp2 like)",
                    "type": "synonym"
                },
                {
                    "name": "jumonji/ARID domain-containing protein 1D",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5D",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5D",
                    "type": "synonym"
                },
                {
                    "name": "protein SmcY",
                    "type": "synonym"
                },
                {
                    "name": "selected mouse cDNA on the Y",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5d",
                    "type": "recommended"
                },
                {
                    "name": "H-Y",
                    "type": "synonym"
                },
                {
                    "name": "HY",
                    "type": "synonym"
                },
                {
                    "name": "Hya",
                    "type": "synonym"
                },
                {
                    "name": "Jarid1d",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5d",
                    "type": "synonym"
                },
                {
                    "name": "Smcy",
                    "type": "synonym"
                }
            ],
            "record_id": "Q62240-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q80Y84-1",
            "uniprot_ac": "Q80Y84",
            "uniprot_id": "KDM5B_MOUSE",
            "refseq_ac": "NP_690855",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5B",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1B",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1B",
                    "type": "synonym"
                },
                {
                    "name": "PLU-1",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5B",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase JARID1B",
                    "type": "synonym"
                },
                {
                    "name": "jumonji, AT rich interactive domain 1B (Rbp2 like)",
                    "type": "synonym"
                },
                {
                    "name": "jumonji/ARID domain-containing protein 1B",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5B",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5B",
                    "type": "synonym"
                },
                {
                    "name": "putative DNA/chromatin binding motif 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5b",
                    "type": "recommended"
                },
                {
                    "name": "2010009J12Rik",
                    "type": "synonym"
                },
                {
                    "name": "2210016I17Rik",
                    "type": "synonym"
                },
                {
                    "name": "D1Ertd202e",
                    "type": "synonym"
                },
                {
                    "name": "Jarid1b",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5b",
                    "type": "synonym"
                },
                {
                    "name": "Kiaa4034",
                    "type": "synonym"
                },
                {
                    "name": "PLU-1",
                    "type": "synonym"
                },
                {
                    "name": "PUT1",
                    "type": "synonym"
                },
                {
                    "name": "Plu1",
                    "type": "synonym"
                },
                {
                    "name": "RBBP2H1A",
                    "type": "synonym"
                },
                {
                    "name": "Rb-Bp2",
                    "type": "synonym"
                },
                {
                    "name": "mKIAA4034",
                    "type": "synonym"
                }
            ],
            "record_id": "Q80Y84-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P41229-1",
            "uniprot_ac": "P41229",
            "uniprot_id": "KDM5C_HUMAN",
            "refseq_ac": "NP_001140174",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5C",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1C",
                    "type": "synonym"
                },
                {
                    "name": "JmjC domain-containing protein SMCX",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji, AT rich interactive domain 1C (RBP2-like)",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1C",
                    "type": "synonym"
                },
                {
                    "name": "Protein SmcX",
                    "type": "synonym"
                },
                {
                    "name": "Protein Xe169",
                    "type": "synonym"
                },
                {
                    "name": "Smcx homolog, X chromosome",
                    "type": "synonym"
                },
                {
                    "name": "Smcy homolog, X-linked",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase JARID1C",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5C isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5C",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "KDM5C",
                    "type": "recommended"
                },
                {
                    "name": "DXS1272E",
                    "type": "synonym"
                },
                {
                    "name": "JARID1C",
                    "type": "synonym"
                },
                {
                    "name": "KDM5C",
                    "type": "synonym"
                },
                {
                    "name": "MRX13",
                    "type": "synonym"
                },
                {
                    "name": "MRXJ",
                    "type": "synonym"
                },
                {
                    "name": "MRXS16",
                    "type": "synonym"
                },
                {
                    "name": "MRXSCJ",
                    "type": "synonym"
                },
                {
                    "name": "MRXSJ",
                    "type": "synonym"
                },
                {
                    "name": "SMCX",
                    "type": "synonym"
                },
                {
                    "name": "XE169",
                    "type": "synonym"
                }
            ],
            "record_id": "P41229-1",
            "evidence": [
                {
                    "id": "300534",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/300534"
                },
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P47156-1",
            "uniprot_ac": "P47156",
            "uniprot_id": "JHD2_YEAST",
            "refseq_ac": "NP_012653",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Histone demethylase JHD2",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 2",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase JHD2",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "JHD2",
                    "type": "recommended"
                },
                {
                    "name": "J2035",
                    "type": "synonym"
                },
                {
                    "name": "JHD2",
                    "type": "synonym"
                },
                {
                    "name": "KDM5",
                    "type": "synonym"
                }
            ],
            "record_id": "P47156-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0ABK0LYB6-1",
            "uniprot_ac": "A0ABK0LYB6",
            "uniprot_id": "A0ABK0LYB6_RAT",
            "refseq_ac": "NP_001406701",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5C",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1C",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1C",
                    "type": "synonym"
                },
                {
                    "name": "Protein SmcX",
                    "type": "synonym"
                },
                {
                    "name": "Protein Xe169",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5C",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5C",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5c",
                    "type": "recommended"
                },
                {
                    "name": "Kdm5c",
                    "type": "synonym"
                },
                {
                    "name": "RGD1560601",
                    "type": "synonym"
                }
            ],
            "record_id": "A0ABK0LYB6-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2K3N6-1",
            "uniprot_ac": "A0A0G2K3N6",
            "uniprot_id": "A0A0G2K3N6_RAT",
            "refseq_ac": "XP_063128368",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5B",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1B",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1B",
                    "type": "synonym"
                },
                {
                    "name": "PLU-1",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5B",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5B isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5b",
                    "type": "recommended"
                },
                {
                    "name": "Jarid1b",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5b",
                    "type": "synonym"
                },
                {
                    "name": "RGD1565602",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0G2K3N6-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A096MJZ8-1",
            "uniprot_ac": "A0A096MJZ8",
            "uniprot_id": "A0A096MJZ8_RAT",
            "refseq_ac": "NP_001264106",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5A",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1A",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1A",
                    "type": "synonym"
                },
                {
                    "name": "Retinoblastoma-binding protein 2",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5A",
                    "type": "synonym"
                },
                {
                    "name": "jumonji, AT rich interactive domain 1A (Rbp2 like)",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5A",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5A isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5A",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5a",
                    "type": "recommended"
                },
                {
                    "name": "Jarid1a",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5a",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A096MJZ8-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2K6V2-1",
            "uniprot_ac": "A0A0G2K6V2",
            "uniprot_id": "A0A0G2K6V2_RAT",
            "refseq_ac": "XP_063136662",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "lysine demethylase 5D isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5d",
                    "type": "recommended"
                },
                {
                    "name": "Jarid1d",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5d",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0G2K6V2-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9VMJ7-1",
            "uniprot_ac": "Q9VMJ7",
            "uniprot_id": "KDM5_DROME",
            "refseq_ac": "NP_001245908",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "CG9088-PC",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase lid",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein lid",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5-PC",
                    "type": "synonym"
                },
                {
                    "name": "Protein little imaginal disks",
                    "type": "synonym"
                },
                {
                    "name": "Retinoblastoma-binding protein 2 homolog",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase Kdm5",
                    "type": "synonym"
                },
                {
                    "name": "lid",
                    "type": "synonym"
                },
                {
                    "name": "little imaginal discs",
                    "type": "synonym"
                },
                {
                    "name": "little imaginal disks",
                    "type": "synonym"
                },
                {
                    "name": "lysine demethylase 5, isoform C",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Kdm5",
                    "type": "recommended"
                },
                {
                    "name": "CG9088",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG9088",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG9088",
                    "type": "synonym"
                },
                {
                    "name": "KDM5",
                    "type": "synonym"
                },
                {
                    "name": "Kdm5",
                    "type": "synonym"
                },
                {
                    "name": "LID",
                    "type": "synonym"
                },
                {
                    "name": "Lid/KDM5",
                    "type": "synonym"
                },
                {
                    "name": "Lid",
                    "type": "synonym"
                },
                {
                    "name": "dJARID1",
                    "type": "synonym"
                },
                {
                    "name": "dKDM5/LID",
                    "type": "synonym"
                },
                {
                    "name": "dKDM5",
                    "type": "synonym"
                },
                {
                    "name": "kdm5",
                    "type": "synonym"
                },
                {
                    "name": "l(2)10424",
                    "type": "synonym"
                },
                {
                    "name": "lid",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9VMJ7-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9UGL1-1",
            "uniprot_ac": "Q9UGL1",
            "uniprot_id": "KDM5B_HUMAN",
            "refseq_ac": "NP_001300971",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5B",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "CT31",
                    "type": "synonym"
                },
                {
                    "name": "Cancer/testis antigen 31",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1B",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1B",
                    "type": "synonym"
                },
                {
                    "name": "PLU-1",
                    "type": "synonym"
                },
                {
                    "name": "RBP2-H1",
                    "type": "synonym"
                },
                {
                    "name": "Retinoblastoma-binding protein 2 homolog 1",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5B",
                    "type": "synonym"
                },
                {
                    "name": "cancer/testis antigen 31",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase JARID1B",
                    "type": "synonym"
                },
                {
                    "name": "jumonji, AT rich interactive domain 1B",
                    "type": "synonym"
                },
                {
                    "name": "jumonji/ARID domain-containing protein 1B",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5B",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5B isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "protein phosphatase 1, regulatory subunit 98",
                    "type": "synonym"
                },
                {
                    "name": "putative DNA/chromatin binding motif",
                    "type": "synonym"
                },
                {
                    "name": "retinoblastoma-binding protein 2 homolog 1",
                    "type": "synonym"
                },
                {
                    "name": "retinoblastoma-binding protein 2, homolog 1A",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "KDM5B",
                    "type": "recommended"
                },
                {
                    "name": "CT31",
                    "type": "synonym"
                },
                {
                    "name": "JARID1B",
                    "type": "synonym"
                },
                {
                    "name": "KDM5B",
                    "type": "synonym"
                },
                {
                    "name": "MRT65",
                    "type": "synonym"
                },
                {
                    "name": "PLU-1",
                    "type": "synonym"
                },
                {
                    "name": "PLU1",
                    "type": "synonym"
                },
                {
                    "name": "PPP1R98",
                    "type": "synonym"
                },
                {
                    "name": "PUT1",
                    "type": "synonym"
                },
                {
                    "name": "RBBP2H1A",
                    "type": "synonym"
                },
                {
                    "name": "RBBP2H1",
                    "type": "synonym"
                },
                {
                    "name": "RBP2-H1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9UGL1-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9BY66-1",
            "uniprot_ac": "Q9BY66",
            "uniprot_id": "KDM5D_HUMAN",
            "refseq_ac": "NP_001140177",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5D",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "H-Y",
                    "type": "synonym"
                },
                {
                    "name": "Histocompatibility Y antigen",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1D",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji, AT rich interactive domain 1D (RBP2-like)",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1D",
                    "type": "synonym"
                },
                {
                    "name": "Protein SmcY",
                    "type": "synonym"
                },
                {
                    "name": "SMC homolog, Y chromosome",
                    "type": "synonym"
                },
                {
                    "name": "Smcy homolog, Y-linked",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5D",
                    "type": "synonym"
                },
                {
                    "name": "epididymis secretory sperm binding protein",
                    "type": "synonym"
                },
                {
                    "name": "histocompatibility Y antigen",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase JARID1D",
                    "type": "synonym"
                },
                {
                    "name": "jumonji/ARID domain-containing protein 1D",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5D",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5D isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "protein SmcY",
                    "type": "synonym"
                },
                {
                    "name": "selected mouse cDNA on Y, human homolog of",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "KDM5D",
                    "type": "recommended"
                },
                {
                    "name": "HYA",
                    "type": "synonym"
                },
                {
                    "name": "HY",
                    "type": "synonym"
                },
                {
                    "name": "JARID1D",
                    "type": "synonym"
                },
                {
                    "name": "KDM5D",
                    "type": "synonym"
                },
                {
                    "name": "KIAA0234",
                    "type": "synonym"
                },
                {
                    "name": "SMCY",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9BY66-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P29375-1",
            "uniprot_ac": "P29375",
            "uniprot_id": "KDM5A_HUMAN",
            "refseq_ac": "NP_001036068",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Lysine-specific demethylase 5A",
                    "type": "recommended"
                },
                {
                    "name": "1.14.11.67",
                    "type": "synonym"
                },
                {
                    "name": "Histone demethylase JARID1A",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji, AT rich interactive domain 1A (RBP2-like)",
                    "type": "synonym"
                },
                {
                    "name": "Jumonji/ARID domain-containing protein 1A",
                    "type": "synonym"
                },
                {
                    "name": "RBBP-2",
                    "type": "synonym"
                },
                {
                    "name": "Retinoblastoma-binding protein 2",
                    "type": "synonym"
                },
                {
                    "name": "[histone H3]-trimethyl-L-lysine(4) demethylase 5A",
                    "type": "synonym"
                },
                {
                    "name": "histone demethylase JARID1A",
                    "type": "synonym"
                },
                {
                    "name": "jumonji/ARID domain-containing protein 1A",
                    "type": "synonym"
                },
                {
                    "name": "lysine (K)-specific demethylase 5A",
                    "type": "synonym"
                },
                {
                    "name": "lysine-specific demethylase 5A",
                    "type": "synonym"
                },
                {
                    "name": "retinoblastoma binding protein 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "KDM5A",
                    "type": "recommended"
                },
                {
                    "name": "JARID1A",
                    "type": "synonym"
                },
                {
                    "name": "KDM5A",
                    "type": "synonym"
                },
                {
                    "name": "NEDEHC",
                    "type": "synonym"
                },
                {
                    "name": "RBBP-2",
                    "type": "synonym"
                },
                {
                    "name": "RBBP2",
                    "type": "synonym"
                },
                {
                    "name": "RBP2",
                    "type": "synonym"
                }
            ],
            "record_id": "P29375-1",
            "evidence": [
                {
                    "id": "0060809",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060809"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0060809"
}