{
    "disease_id": "DOID:0060750",
    "recommended_name": {
        "id": "DOID:0060750",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060750",
        "name": "familial temporal lobe epilepsy 3",
        "description": "A temporal lobe epilepsy characterized by simple or complex partial seizures often accompanied by intense feelings of deja or altered awareness and that has_material_basis_in variation in the chromosome region 4q13.2-q21.3."
    },
    "synonyms": [
        {
            "id": "DOID:0060750",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060750",
            "name": "FMTLE",
            "description": ""
        },
        {
            "id": "DOID:0060750",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060750",
            "name": "familial mesial temporal lobe epilepsy",
            "description": ""
        },
        {
            "id": "MONDO:0012705",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012705",
            "name": "familial temporal lobe epilepsy 3",
            "description": ""
        },
        {
            "id": "MONDO:0012705",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012705",
            "name": "FMTLE",
            "description": ""
        },
        {
            "id": "MONDO:0012705",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012705",
            "name": "familial mesial temporal lobe epilepsy",
            "description": ""
        },
        {
            "id": "MONDO:0012705",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012705",
            "name": "ETL3",
            "description": ""
        },
        {
            "id": "MONDO:0012705",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012705",
            "name": "epilepsy, familial temporal lobe, 3",
            "description": ""
        },
        {
            "id": "MONDO:0012705",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012705",
            "name": "familial temporal lobe epilepsy type 3",
            "description": ""
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0060750"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0060750",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060750",
            "categories": []
        },
        {
            "id": "MONDO:0012705",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012705",
            "categories": []
        }
    ],
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        {
            "uniprot_canonical_ac": "P21447-1",
            "uniprot_ac": "P21447",
            "uniprot_id": "MDR1A_MOUSE",
            "refseq_ac": "NP_035206",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
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                    "name": "ATP-dependent translocase ABCB1",
                    "type": "recommended"
                },
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                    "type": "synonym"
                },
                {
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                    "type": "synonym"
                },
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                    "name": "ATP-binding cassette sub-family B member 1A",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette, sub-family B (MDR/TAP), member 1A",
                    "type": "synonym"
                },
                {
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                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette, subfamily B, member 1A",
                    "type": "synonym"
                },
                {
                    "name": "ATP-dependent translocase ABCB1",
                    "type": "synonym"
                },
                {
                    "name": "MDR1A",
                    "type": "synonym"
                },
                {
                    "name": "Multidrug resistance protein 1A",
                    "type": "synonym"
                },
                {
                    "name": "Multidrug resistance protein 3",
                    "type": "synonym"
                },
                {
                    "name": "P-glycoprotein 3",
                    "type": "synonym"
                },
                {
                    "name": "Phospholipid transporter ABCB1",
                    "type": "synonym"
                },
                {
                    "name": "ecotropic viral integration site 32",
                    "type": "synonym"
                },
                {
                    "name": "multi-drug resistance 3",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance protein 3",
                    "type": "synonym"
                },
                {
                    "name": "multiple drug resistant 1a",
                    "type": "synonym"
                },
                {
                    "name": "phospholipid transporter ABCB1",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "Abcb1a",
                    "type": "recommended"
                },
                {
                    "name": "Abcb1a",
                    "type": "synonym"
                },
                {
                    "name": "Abcb4",
                    "type": "synonym"
                },
                {
                    "name": "Evi32",
                    "type": "synonym"
                },
                {
                    "name": "Mdr1a",
                    "type": "synonym"
                },
                {
                    "name": "Mdr3",
                    "type": "synonym"
                },
                {
                    "name": "P-gp",
                    "type": "synonym"
                },
                {
                    "name": "Pgp",
                    "type": "synonym"
                },
                {
                    "name": "Pgy-3",
                    "type": "synonym"
                },
                {
                    "name": "Pgy3",
                    "type": "synonym"
                },
                {
                    "name": "mdr-3",
                    "type": "synonym"
                }
            ],
            "record_id": "P21447-1",
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                {
                    "id": "0060750",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060750"
                }
            ]
        },
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                    "taxid": 10090,
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                }
            ],
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                    "name": "ATP-dependent translocase ABCB1",
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                    "name": "7.6.2.1",
                    "type": "synonym"
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                {
                    "name": "7.6.2.2",
                    "type": "synonym"
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                {
                    "name": "ATP-binding cassette sub-family B member 1B",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette sub-family B member 1",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette, sub-family B (MDR/TAP), member 1B",
                    "type": "synonym"
                },
                {
                    "name": "ATP-dependent translocase ABCB1",
                    "type": "synonym"
                },
                {
                    "name": "Multidrug resistance protein 1B",
                    "type": "synonym"
                },
                {
                    "name": "P glycoprotein 1",
                    "type": "synonym"
                },
                {
                    "name": "P-glycoprotein 1",
                    "type": "synonym"
                },
                {
                    "name": "Phospholipid transporter ABCB1",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance protein 1B",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance protein 1",
                    "type": "synonym"
                },
                {
                    "name": "phospholipid transporter ABCB1",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "Abcb1b",
                    "type": "recommended"
                },
                {
                    "name": "Abcb1b",
                    "type": "synonym"
                },
                {
                    "name": "Abcb1",
                    "type": "synonym"
                },
                {
                    "name": "Mdr1b",
                    "type": "synonym"
                },
                {
                    "name": "Mdr1",
                    "type": "synonym"
                },
                {
                    "name": "Pgy-1",
                    "type": "synonym"
                },
                {
                    "name": "Pgy1-1",
                    "type": "synonym"
                },
                {
                    "name": "Pgy1",
                    "type": "synonym"
                },
                {
                    "name": "mdr",
                    "type": "synonym"
                }
            ],
            "record_id": "P06795-1",
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                {
                    "id": "0060750",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060750"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P12866-1",
            "uniprot_ac": "P12866",
            "uniprot_id": "STE6_YEAST",
            "refseq_ac": "NP_012713",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Alpha-factor-transporting ATPase",
                    "type": "recommended"
                },
                {
                    "name": "7.4.2.7",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette a-factor transporter STE6",
                    "type": "synonym"
                },
                {
                    "name": "Mating factor A secretion protein STE6",
                    "type": "synonym"
                },
                {
                    "name": "Multiple drug resistance protein homolog",
                    "type": "synonym"
                },
                {
                    "name": "P-glycoprotein",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "STE6",
                    "type": "recommended"
                },
                {
                    "name": "STE6",
                    "type": "synonym"
                }
            ],
            "record_id": "P12866-1",
            "evidence": [
                {
                    "id": "0060750",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060750"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P43245-1",
            "uniprot_ac": "P43245",
            "uniprot_id": "MDR1_RAT",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
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                {
                    "name": "ATP-dependent translocase ABCB1",
                    "type": "recommended"
                },
                {
                    "name": "7.6.2.1",
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                {
                    "name": "7.6.2.2",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette sub-family B member 1",
                    "type": "synonym"
                },
                {
                    "name": "Multidrug resistance protein 1",
                    "type": "synonym"
                },
                {
                    "name": "P-glycoprotein 1",
                    "type": "synonym"
                },
                {
                    "name": "Phospholipid transporter ABCB1",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "Abcb1a",
                    "type": "recommended"
                },
                {
                    "name": "Abcb1b",
                    "type": "recommended"
                },
                {
                    "name": "Abcb1",
                    "type": "recommended"
                },
                {
                    "name": "Abcb4",
                    "type": "recommended"
                },
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                    "name": "Abcb1a",
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                },
                {
                    "name": "Abcb1b",
                    "type": "synonym"
                },
                {
                    "name": "Abcb1",
                    "type": "synonym"
                },
                {
                    "name": "Abcb4",
                    "type": "synonym"
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                {
                    "name": "Mdr1b",
                    "type": "synonym"
                },
                {
                    "name": "Mdr1",
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                {
                    "name": "Pgy1",
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                }
            ],
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                    "id": "0060750",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0060750"
                }
            ]
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        {
            "uniprot_canonical_ac": "Q00449-1",
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                {
                    "name": "Drosophila melanogaster",
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                }
            ],
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                    "name": "Multidrug resistance protein homolog 49",
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                    "name": "7.6.2.2",
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                    "name": "CG3879-PB",
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                    "name": "Mdr49-PB",
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                {
                    "name": "P-glycoprotein 49",
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                {
                    "name": "multi drug resistance 49, isoform B",
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                }
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                    "name": "Mdr49",
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                    "name": "CG3879",
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                    "name": "Dm5",
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                },
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                    "name": "DmMdr49",
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                },
                {
                    "name": "Dmel\\CG3879",
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                    "name": "Dmel_CG3879",
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                    "name": "MDR5",
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                    "name": "Mdr49",
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                    "name": "Mes5",
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                    "name": "mdr49",
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                    "name": "mrd49",
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                    "id": "0060750",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0060750"
                }
            ]
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            "uniprot_canonical_ac": "Q00748-1",
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            "species": [
                {
                    "name": "Drosophila melanogaster",
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                }
            ],
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                    "name": "Multidrug resistance protein homolog 65",
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                    "name": "7.6.2.2",
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                    "name": "CG10181-PA",
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                    "name": "MDR65",
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                {
                    "name": "Mdr65-PA",
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                    "name": "P-glycoprotein 65",
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                {
                    "name": "P-glycoprotein65-Dm",
                    "type": "synonym"
                },
                {
                    "name": "multi drug resistance 65",
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                {
                    "name": "multiple drug resistance 65",
                    "type": "synonym"
                }
            ],
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                    "name": "Mdr65",
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                    "name": "CG10181",
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                    "name": "DmMdr65",
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                    "name": "Dmel\\CG10181",
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                    "name": "MDR65",
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                    "name": "Mdr65A",
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                    "name": "Mdr65",
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                {
                    "name": "P-glycoprotein",
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                {
                    "name": "P-gp",
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                    "name": "mdr65",
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                    "id": "0060750",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0060750"
                }
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            "uniprot_canonical_ac": "Q9VRW2-1",
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                {
                    "name": "Drosophila melanogaster",
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                    "common_name": "Fruit fly",
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                }
            ],
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                    "name": "Multidrug resistance protein homolog 65",
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                {
                    "name": "ABC multidrug transporter",
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                },
                {
                    "name": "CG10226-PA",
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                {
                    "name": "uncharacterized protein, isoform A",
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                }
            ],
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                    "name": "AMT",
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                {
                    "name": "Dmel\\CG10226",
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                    "name": "AMT",
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                    "name": "CG10226",
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                    "name": "DmCG10226",
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                {
                    "name": "Dmel\\CG10226",
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                {
                    "name": "Dmel_CG10226",
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                    "id": "0060750",
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            "uniprot_canonical_ac": "P78545-1",
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                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "ETS-related transcription factor Elf-3",
                    "type": "recommended"
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                {
                    "name": "E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific)",
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                },
                {
                    "name": "E74-like factor 3 (ets domain transcription factor)",
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                },
                {
                    "name": "E74-like factor 3 (ets domain transcription factor, epithelial-specific)",
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                },
                {
                    "name": "E74-like factor 3",
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                {
                    "name": "ESE-1",
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                {
                    "name": "ETS-related transcription factor Elf-3",
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                },
                {
                    "name": "Epithelial-restricted with serine box",
                    "type": "synonym"
                },
                {
                    "name": "Epithelium-restricted Ets protein ESX",
                    "type": "synonym"
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                {
                    "name": "Epithelium-specific Ets transcription factor 1",
                    "type": "synonym"
                },
                {
                    "name": "epithelial-restricted with serine box",
                    "type": "synonym"
                },
                {
                    "name": "epithelium-restricted Ets protein ESX",
                    "type": "synonym"
                },
                {
                    "name": "epithelium-specific Ets transcription factor 1",
                    "type": "synonym"
                },
                {
                    "name": "ets domain transcription factor, serine box (epithelial-specific)",
                    "type": "synonym"
                }
            ],
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                    "name": "ELF3",
                    "type": "recommended"
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                {
                    "name": "ELF3",
                    "type": "synonym"
                },
                {
                    "name": "EPR-1",
                    "type": "synonym"
                },
                {
                    "name": "ERT",
                    "type": "synonym"
                },
                {
                    "name": "ESE-1",
                    "type": "synonym"
                },
                {
                    "name": "ESX",
                    "type": "synonym"
                },
                {
                    "name": "JEN",
                    "type": "synonym"
                }
            ],
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                    "id": "0060750",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060750"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P08183-1",
            "uniprot_ac": "P08183",
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            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                {
                    "name": "ATP-dependent translocase ABCB1",
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                    "name": "7.6.2.1",
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                },
                {
                    "name": "7.6.2.2",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette sub-family B member 1",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette, sub-family B (MDR/TAP), member 1",
                    "type": "synonym"
                },
                {
                    "name": "ATP-dependent translocase ABCB1 isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "ATP-dependent translocase ABCB1",
                    "type": "synonym"
                },
                {
                    "name": "Multidrug resistance protein 1",
                    "type": "synonym"
                },
                {
                    "name": "P-glycoprotein 1",
                    "type": "synonym"
                },
                {
                    "name": "Phospholipid transporter ABCB1",
                    "type": "synonym"
                },
                {
                    "name": "colchicin sensitivity",
                    "type": "synonym"
                },
                {
                    "name": "doxorubicin resistance",
                    "type": "synonym"
                },
                {
                    "name": "multidrug resistance protein 1",
                    "type": "synonym"
                },
                {
                    "name": "phospholipid transporter ABCB1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ABCB1",
                    "type": "recommended"
                },
                {
                    "name": "ABC20",
                    "type": "synonym"
                },
                {
                    "name": "ABCB1",
                    "type": "synonym"
                },
                {
                    "name": "CD243",
                    "type": "synonym"
                },
                {
                    "name": "CLCS",
                    "type": "synonym"
                },
                {
                    "name": "ENPAT",
                    "type": "synonym"
                },
                {
                    "name": "GP170",
                    "type": "synonym"
                },
                {
                    "name": "MDR1",
                    "type": "synonym"
                },
                {
                    "name": "P-GP",
                    "type": "synonym"
                },
                {
                    "name": "PGY1",
                    "type": "synonym"
                },
                {
                    "name": "p-170",
                    "type": "synonym"
                }
            ],
            "record_id": "P08183-1",
            "evidence": [
                {
                    "id": "0060750",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060750"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0060750"
}