{
    "disease_id": "DOID:0060672",
    "recommended_name": {
        "id": "DOID:0060672",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060672",
        "name": "frontotemporal dementia 2",
        "description": "A frontotemporal dementia characterized by variable phenotypic expression typically including social, behavioral, or language deterioration, rather than memory or motor deficits and the presence of TARDBP-positive inclusions that has_material_basis_in mutation in the GRN gene on chromosome 17q21.31."
    },
    "synonyms": [
        {
            "id": "DOID:0060672",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060672",
            "name": "GRN-related frontotemporal lobar degeneration with Tdp43 inclusions",
            "description": ""
        },
        {
            "id": "MONDO:0011842",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011842",
            "name": "GRN-related frontotemporal lobar degeneration with Tdp43 inclusions",
            "description": "A frontotemporal dementia characterized by variable phenotypic expression typically including social, behavioral, or language deterioration, rather than memory or motor deficits and the presence of TARDBP-positive inclusions that has material basis in mutation in the GRN gene on chromosome 17q21.31."
        },
        {
            "id": "MIM:607485",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/607485",
            "name": "Frontotemporal dementia 2",
            "description": "Frontotemporal dementia 2"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0060672"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0060672",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060672",
            "categories": []
        },
        {
            "id": "MONDO:0011842",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011842",
            "categories": []
        },
        {
            "id": "MIM:607485",
            "database": "MIM",
            "url": "https://www.omim.org/entry/607485",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0AC58IPJ6-1",
            "uniprot_ac": "A0AC58IPJ6",
            "uniprot_id": "A0AC58IPJ6_DANRE",
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            "species": [
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                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
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                    "type": "synonym"
                },
                {
                    "name": "granulin b isoform X1",
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                    "name": "grnb",
                    "type": "recommended"
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                    "name": "fj14b08",
                    "type": "synonym"
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                    "type": "synonym"
                },
                {
                    "name": "wu:fj14b08",
                    "type": "synonym"
                },
                {
                    "name": "zgc:111858",
                    "type": "synonym"
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                }
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        },
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                    "name": "Danio rerio",
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                },
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                    "name": "sb:eu337",
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                    "name": "wu:fb11g12",
                    "type": "synonym"
                },
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                }
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                    "name": "tardbpa",
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                }
            ],
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                }
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                    "id": "0060672",
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                }
            ]
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            "uniprot_canonical_ac": "P28798-1",
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                    "name": "Mus musculus",
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                }
            ],
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                    "name": "Progranulin",
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                },
                {
                    "name": "Acrogranin",
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                {
                    "name": "GP88",
                    "type": "synonym"
                },
                {
                    "name": "Glycoprotein 88",
                    "type": "synonym"
                },
                {
                    "name": "Glycoprotein of 88 Kda",
                    "type": "synonym"
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                    "name": "PC cell-derived growth factor",
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                    "name": "proepithelin",
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                    "name": "Transmembrane protein 106B",
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                    "name": "TMEM106B",
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                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "TAR DNA-binding protein 43",
                    "type": "recommended"
                },
                {
                    "name": "TAR DNA-binding protein 43",
                    "type": "synonym"
                },
                {
                    "name": "TAR DNA-binding protein-43",
                    "type": "synonym"
                },
                {
                    "name": "TDP-43",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "TARDBP",
                    "type": "recommended"
                },
                {
                    "name": "ALS10",
                    "type": "synonym"
                },
                {
                    "name": "TARDBP",
                    "type": "synonym"
                },
                {
                    "name": "TDP-43",
                    "type": "synonym"
                },
                {
                    "name": "TDP43",
                    "type": "synonym"
                }
            ],
            "record_id": "Q13148-1",
            "evidence": [
                {
                    "id": "0060672",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060672"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0060672"
}