{
    "disease_id": "DOID:0060645",
    "recommended_name": {
        "id": "DOID:0060645",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060645",
        "name": "chronic recurrent multifocal osteomyelitis",
        "description": "An osteomyelitis characterized by multiple foci of painful swelling of bones, mainly in the metaphyses of the long bones, in addition to the pelvis, the shoulder girdle and the spine."
    },
    "synonyms": [
        {
            "id": "DOID:0060645",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060645",
            "name": "CRMO",
            "description": ""
        },
        {
            "id": "DOID:0060645",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060645",
            "name": "chronic multifocal osteomyelitis",
            "description": ""
        },
        {
            "id": "MONDO:0958177",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0958177",
            "name": "chronic recurrent multifocal osteomyelitis 3",
            "description": ""
        },
        {
            "id": "MIM:259680",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/259680",
            "name": "Chronic recurrent multifocal osteomyelitis 3",
            "description": "Chronic recurrent multifocal osteomyelitis 3"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0060645"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0060645",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060645",
            "categories": []
        },
        {
            "id": "MONDO:0958177",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0958177",
            "categories": []
        },
        {
            "id": "MIM:259680",
            "database": "MIM",
            "url": "https://www.omim.org/entry/259680",
            "categories": []
        }
    ],
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        {
            "uniprot_canonical_ac": "A0A8M3BCU8-1",
            "uniprot_ac": "A0A8M3BCU8",
            "uniprot_id": "A0A8M3BCU8_DANRE",
            "refseq_ac": "XP_009303409",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Proline-serine-threonine phosphatase-interacting protein 2",
                    "type": "recommended"
                },
                {
                    "name": "proline-serine-threonine phosphatase-interacting protein 2 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "pstpip2",
                    "type": "recommended"
                },
                {
                    "name": "pstpip2",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0060645",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060645"
                }
            ]
        },
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            "uniprot_canonical_ac": "Q99M15-1",
            "uniprot_ac": "Q99M15",
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            "refseq_ac": "NP_038859",
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                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
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                {
                    "name": "Proline-serine-threonine phosphatase-interacting protein 2",
                    "type": "recommended"
                },
                {
                    "name": "Macrophage actin-associated tyrosine-phosphorylated protein",
                    "type": "synonym"
                },
                {
                    "name": "PEST phosphatase-interacting protein 2",
                    "type": "synonym"
                },
                {
                    "name": "macrophage actin-associated tyrosine-phosphorylated protein",
                    "type": "synonym"
                },
                {
                    "name": "pp37",
                    "type": "synonym"
                },
                {
                    "name": "proline-serine-threonine phosphatase-interacting protein 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pstpip2",
                    "type": "recommended"
                },
                {
                    "name": "MAYP",
                    "type": "synonym"
                },
                {
                    "name": "Mayp",
                    "type": "synonym"
                },
                {
                    "name": "Pstpip2",
                    "type": "synonym"
                },
                {
                    "name": "cmo",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0060645",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0060645"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P13504-1",
            "uniprot_ac": "P13504",
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            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Interleukin-1 receptor type 1",
                    "type": "recommended"
                },
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                    "name": "3.2.2.6",
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                },
                {
                    "name": "CD121 antigen-like family member A",
                    "type": "synonym"
                },
                {
                    "name": "IL-1 receptor alpha chain",
                    "type": "synonym"
                },
                {
                    "name": "IL-1R-1",
                    "type": "synonym"
                },
                {
                    "name": "IL-1R-alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL-1RT-1",
                    "type": "synonym"
                },
                {
                    "name": "IL-1RT1",
                    "type": "synonym"
                },
                {
                    "name": "Interleukin-1 receptor alpha",
                    "type": "synonym"
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                {
                    "name": "Interleukin-1 receptor type I",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-1 receptor alpha",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-1 receptor type 1 isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-1 receptor type 1",
                    "type": "synonym"
                },
                {
                    "name": "p80",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "Il1r1",
                    "type": "recommended"
                },
                {
                    "name": "CD121a",
                    "type": "synonym"
                },
                {
                    "name": "CD121b",
                    "type": "synonym"
                },
                {
                    "name": "IL-1R-1",
                    "type": "synonym"
                },
                {
                    "name": "IL-1R-alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL-1R1",
                    "type": "synonym"
                },
                {
                    "name": "IL-1RT-1",
                    "type": "synonym"
                },
                {
                    "name": "IL-1RT1",
                    "type": "synonym"
                },
                {
                    "name": "IL-iR",
                    "type": "synonym"
                },
                {
                    "name": "Il-1r1",
                    "type": "synonym"
                },
                {
                    "name": "Il1r-1",
                    "type": "synonym"
                },
                {
                    "name": "Il1r1",
                    "type": "synonym"
                },
                {
                    "name": "Il1ra",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0060645",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060645"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P14778-1",
            "uniprot_ac": "P14778",
            "uniprot_id": "IL1R1_HUMAN",
            "refseq_ac": "NP_001275635",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Interleukin-1 receptor type 1",
                    "type": "recommended"
                },
                {
                    "name": "3.2.2.6",
                    "type": "synonym"
                },
                {
                    "name": "CD121 antigen-like family member A",
                    "type": "synonym"
                },
                {
                    "name": "IL-1R-1",
                    "type": "synonym"
                },
                {
                    "name": "IL-1R-alpha",
                    "type": "synonym"
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                {
                    "name": "IL-1RT-1",
                    "type": "synonym"
                },
                {
                    "name": "IL-1RT1",
                    "type": "synonym"
                },
                {
                    "name": "Interleukin-1 receptor alpha",
                    "type": "synonym"
                },
                {
                    "name": "Interleukin-1 receptor type I",
                    "type": "synonym"
                },
                {
                    "name": "interleukin 1 receptor alpha, type I",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-1 receptor alpha",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-1 receptor type 1 isoform 2 precursor",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-1 receptor type I",
                    "type": "synonym"
                },
                {
                    "name": "p80",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "IL1R1",
                    "type": "recommended"
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                    "name": "CRMO3",
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                {
                    "name": "IL-1R-alpha",
                    "type": "synonym"
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                {
                    "name": "IL-1RT1",
                    "type": "synonym"
                },
                {
                    "name": "IL1R1",
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                    "name": "IL1RA",
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                    "name": "IL1R",
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                },
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                    "id": "259680",
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                {
                    "id": "0060645",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060645"
                }
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            "uniprot_canonical_ac": "P43556-1",
            "uniprot_ac": "P43556",
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            "refseq_ac": "NP_428268",
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                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
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                }
            ],
            "protein_names": [
                {
                    "name": "Rho-GTPase-activating protein RGD2",
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                {
                    "name": "GTPase-activating protein RGD2",
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                }
            ],
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                    "name": "RGD2",
                    "type": "recommended"
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                    "id": "0060645",
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            "uniprot_canonical_ac": "Q02955-1",
            "uniprot_ac": "Q02955",
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            "refseq_ac": "",
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                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
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                    "name": "CD121 antigen-like family member A",
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                {
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                {
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                {
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                    "id": "0060645",
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                }
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            "uniprot_canonical_ac": "A0ABK0LW07-1",
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                    "name": "Rattus norvegicus",
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                    "name": "Proline-serine-threonine phosphatase-interacting protein 2",
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                    "name": "proline-serine-threonine phosphatase-interacting protein 2",
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                    "name": "Pstpip2",
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                    "id": "0060645",
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            "uniprot_canonical_ac": "Q9UBU2-1",
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                }
            ],
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                {
                    "name": "Dickkopf-related protein 2",
                    "type": "recommended"
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                    "name": "Dickkopf-2",
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                },
                {
                    "name": "Dkk-2",
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                },
                {
                    "name": "dickkopf 2 homolog",
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                {
                    "name": "dickkopf homolog 2",
                    "type": "synonym"
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                    "name": "dickkopf-2",
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                {
                    "name": "dickkopf-related protein 2 precursor",
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                {
                    "name": "dickkopf-related protein 2",
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                    "name": "hDkk-2",
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                    "name": "DKK2",
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                {
                    "name": "DKK-2",
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                },
                {
                    "name": "DKK2",
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                    "name": "PRO1316",
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                    "id": "0060645",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0060645"
                }
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                {
                    "name": "Homo sapiens",
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                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                    "name": "Proline-serine-threonine phosphatase-interacting protein 2",
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                },
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                    "name": "PEST phosphatase-interacting protein 2",
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                    "name": "PSTPIP2",
                    "type": "recommended"
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                {
                    "name": "MAYP",
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                {
                    "name": "PSTPIP2",
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                    "id": "0060645",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060645"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0060645"
}