{
    "disease_id": "DOID:0060604",
    "recommended_name": {
        "id": "DOID:0060604",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060604",
        "name": "ankyloglossia",
        "description": "A tongue disease characterized by an unusually short, thick lingual frenulum, a membrane connecting the underside of the tongue to the floor of the mouth."
    },
    "synonyms": [
        {
            "id": "DOID:0060604",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060604",
            "name": "tongue-tie",
            "description": ""
        },
        {
            "id": "MONDO:0007125",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007125",
            "name": "ankyloglossia",
            "description": "A developmental abnormality in which the bottom of the tongue is attached to the floor of the mouth."
        },
        {
            "id": "MONDO:0007125",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007125",
            "name": "FUSED to floor of mouth",
            "description": ""
        },
        {
            "id": "MONDO:0007125",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007125",
            "name": "ankyloglossia",
            "description": ""
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0060604"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0060604",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060604",
            "categories": []
        },
        {
            "id": "MONDO:0007125",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007125",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q9Z1P4-1",
            "uniprot_ac": "Q9Z1P4",
            "uniprot_id": "LGR5_MOUSE",
            "refseq_ac": "NP_034325",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat-containing G protein-coupled receptor 5",
                    "type": "recommended"
                },
                {
                    "name": "G protein-coupled receptor 49",
                    "type": "synonym"
                },
                {
                    "name": "Orphan G protein-coupled receptor FEX",
                    "type": "synonym"
                },
                {
                    "name": "follicle expressed hormone",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing G-protein coupled receptor 5 precursor",
                    "type": "synonym"
                },
                {
                    "name": "orphan G-protein coupled receptor FEX",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Lgr5",
                    "type": "recommended"
                },
                {
                    "name": "FEX",
                    "type": "synonym"
                },
                {
                    "name": "Fex",
                    "type": "synonym"
                },
                {
                    "name": "Gpr49",
                    "type": "synonym"
                },
                {
                    "name": "Lgr5",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9Z1P4-1",
            "evidence": [
                {
                    "id": "0060604",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060604"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "D4AC13-1",
            "uniprot_ac": "D4AC13",
            "uniprot_id": "LGR5_RAT",
            "refseq_ac": "NP_001100254",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat-containing G protein-coupled receptor 5",
                    "type": "recommended"
                },
                {
                    "name": "G protein-coupled receptor 49",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing G-protein coupled receptor 5 precursor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Lgr5",
                    "type": "recommended"
                },
                {
                    "name": "Gpr49",
                    "type": "synonym"
                },
                {
                    "name": "Lgr5",
                    "type": "synonym"
                }
            ],
            "record_id": "D4AC13-1",
            "evidence": [
                {
                    "id": "0060604",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060604"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q7KTA0-1",
            "uniprot_ac": "Q7KTA0",
            "uniprot_id": "Q7KTA0_DROME",
            "refseq_ac": "NP_476702",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "CG8930-PA",
                    "type": "synonym"
                },
                {
                    "name": "Rickets",
                    "type": "synonym"
                },
                {
                    "name": "glycoprotein hormone receptor II",
                    "type": "synonym"
                },
                {
                    "name": "glycoprotein-hormone-receptor-II",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing G protein-coupled receptor 2",
                    "type": "synonym"
                },
                {
                    "name": "rickets",
                    "type": "synonym"
                },
                {
                    "name": "rk-PA",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "rk",
                    "type": "recommended"
                },
                {
                    "name": "BG:DS00180.13",
                    "type": "synonym"
                },
                {
                    "name": "CG8930",
                    "type": "synonym"
                },
                {
                    "name": "CT25644",
                    "type": "synonym"
                },
                {
                    "name": "DLGR-2",
                    "type": "synonym"
                },
                {
                    "name": "DLGR2",
                    "type": "synonym"
                },
                {
                    "name": "DLgr2",
                    "type": "synonym"
                },
                {
                    "name": "Dlgr2",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG8930",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG8930",
                    "type": "synonym"
                },
                {
                    "name": "LGR2",
                    "type": "synonym"
                },
                {
                    "name": "Lgr2",
                    "type": "synonym"
                },
                {
                    "name": "Rk",
                    "type": "synonym"
                },
                {
                    "name": "dLGR2",
                    "type": "synonym"
                },
                {
                    "name": "dlgr2/rk",
                    "type": "synonym"
                },
                {
                    "name": "dlgr2",
                    "type": "synonym"
                },
                {
                    "name": "lgr2",
                    "type": "synonym"
                },
                {
                    "name": "rk/CG8930",
                    "type": "synonym"
                },
                {
                    "name": "rk",
                    "type": "synonym"
                }
            ],
            "record_id": "Q7KTA0-1",
            "evidence": [
                {
                    "id": "0060604",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060604"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O75473-1",
            "uniprot_ac": "O75473",
            "uniprot_id": "LGR5_HUMAN",
            "refseq_ac": "NP_001264155",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat-containing G protein-coupled receptor 5",
                    "type": "recommended"
                },
                {
                    "name": "G protein-coupled receptor 49",
                    "type": "synonym"
                },
                {
                    "name": "G protein-coupled receptor 67",
                    "type": "synonym"
                },
                {
                    "name": "G protein-coupled receptor HG38",
                    "type": "synonym"
                },
                {
                    "name": "G-protein coupled receptor 49",
                    "type": "synonym"
                },
                {
                    "name": "G-protein coupled receptor 67",
                    "type": "synonym"
                },
                {
                    "name": "G-protein coupled receptor HG38",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing G-protein coupled receptor 5 isoform 2 precursor",
                    "type": "synonym"
                },
                {
                    "name": "orphan G protein-coupled receptor HG38",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "LGR5",
                    "type": "recommended"
                },
                {
                    "name": "FEX",
                    "type": "synonym"
                },
                {
                    "name": "GPR49",
                    "type": "synonym"
                },
                {
                    "name": "GPR67",
                    "type": "synonym"
                },
                {
                    "name": "GRP49",
                    "type": "synonym"
                },
                {
                    "name": "HG38",
                    "type": "synonym"
                },
                {
                    "name": "LGR5",
                    "type": "synonym"
                }
            ],
            "record_id": "O75473-1",
            "evidence": [
                {
                    "id": "0060604",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060604"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0060604"
}