{
    "disease_id": "DOID:0060257",
    "recommended_name": {
        "id": "DOID:0060257",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060257",
        "name": "dyschromatosis symmetrica hereditaria",
        "description": "A pigmentation disease characterized by progressively pigmented and depigmented macules, often mixed in a reticulate pattern, concentrated on the dorsal extremities."
    },
    "synonyms": [
        {
            "id": "DOID:0060257",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060257",
            "name": "reticulate acropigmentation of Dohi",
            "description": ""
        },
        {
            "id": "MONDO:0007483",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "name": "dyschromatosis symmetrica hereditaria",
            "description": "Acropigmentation of Dohi is a genodermatosis characterized by the presence of hyperpigmented and hypopigmented macules, principally located on the extremities and limbs."
        },
        {
            "id": "MONDO:0007483",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "name": "DSH1",
            "description": ""
        },
        {
            "id": "MONDO:0007483",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "name": "RAD",
            "description": ""
        },
        {
            "id": "MONDO:0007483",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "name": "acropigmentation of Dohi",
            "description": ""
        },
        {
            "id": "MONDO:0007483",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "name": "dyschromatosis symmetrica hereditaria",
            "description": ""
        },
        {
            "id": "MONDO:0007483",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "name": "reticulate acropigmentation of Dohi",
            "description": ""
        },
        {
            "id": "MONDO:0007483",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "name": "DSH",
            "description": ""
        },
        {
            "id": "MONDO:0007483",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "name": "familial reticulate acropigmentation of Dohi",
            "description": ""
        },
        {
            "id": "MIM:127400",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/127400",
            "name": "Dyschromatosis symmetrica hereditaria",
            "description": "Dyschromatosis symmetrica hereditaria"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0060257"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0060257",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060257",
            "categories": []
        },
        {
            "id": "MONDO:0007483",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0007483",
            "categories": []
        },
        {
            "id": "MIM:127400",
            "database": "MIM",
            "url": "https://www.omim.org/entry/127400",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8M1P8J0-1",
            "uniprot_ac": "A0A8M1P8J0",
            "uniprot_id": "A0A8M1P8J0_DANRE",
            "refseq_ac": "NP_571671",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "3.5.4.37",
                    "type": "synonym"
                },
                {
                    "name": "Double-stranded RNA-specific adenosine deaminase",
                    "type": "synonym"
                },
                {
                    "name": "double-stranded RNA-specific adenosine deaminase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "adar",
                    "type": "recommended"
                },
                {
                    "name": "adar",
                    "type": "synonym"
                },
                {
                    "name": "drada",
                    "type": "synonym"
                },
                {
                    "name": "red1",
                    "type": "synonym"
                },
                {
                    "name": "wu:fc22a02",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M1P8J0-1",
            "evidence": [
                {
                    "id": "0060257",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060257"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q99MU3-1",
            "uniprot_ac": "Q99MU3",
            "uniprot_id": "DSRAD_MOUSE",
            "refseq_ac": "NP_001139768",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Double-stranded RNA-specific adenosine deaminase",
                    "type": "recommended"
                },
                {
                    "name": "3.5.4.37",
                    "type": "synonym"
                },
                {
                    "name": "DRADA",
                    "type": "synonym"
                },
                {
                    "name": "RNA adenosine deaminase 1",
                    "type": "synonym"
                },
                {
                    "name": "RNA-specific adenosine deaminase p110 form",
                    "type": "synonym"
                },
                {
                    "name": "RNA-specific adenosine deaminase p150 form",
                    "type": "synonym"
                },
                {
                    "name": "double-stranded RNA-specific adenosine deaminase isoform 3",
                    "type": "synonym"
                },
                {
                    "name": "double-stranded RNA-specific adenosine deaminase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Adar",
                    "type": "recommended"
                },
                {
                    "name": "Adar1p110",
                    "type": "synonym"
                },
                {
                    "name": "Adar1p150",
                    "type": "synonym"
                },
                {
                    "name": "Adar1",
                    "type": "synonym"
                },
                {
                    "name": "Adar",
                    "type": "synonym"
                },
                {
                    "name": "DRADA",
                    "type": "synonym"
                },
                {
                    "name": "mZaADAR",
                    "type": "synonym"
                }
            ],
            "record_id": "Q99MU3-1",
            "evidence": [
                {
                    "id": "0060257",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060257"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P55265-1",
            "uniprot_ac": "P55265",
            "uniprot_id": "DSRAD_HUMAN",
            "refseq_ac": "NP_001020278",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Double-stranded RNA-specific adenosine deaminase",
                    "type": "recommended"
                },
                {
                    "name": "136 kDa double-stranded RNA-binding protein",
                    "type": "synonym"
                },
                {
                    "name": "3.5.4.37",
                    "type": "synonym"
                },
                {
                    "name": "DRADA",
                    "type": "synonym"
                },
                {
                    "name": "IFI-4",
                    "type": "synonym"
                },
                {
                    "name": "Interferon-inducible protein 4",
                    "type": "synonym"
                },
                {
                    "name": "K88DSRBP",
                    "type": "synonym"
                },
                {
                    "name": "adenosine deaminase acting on RNA 1-A",
                    "type": "synonym"
                },
                {
                    "name": "double-stranded RNA-specific adenosine deaminase isoform d",
                    "type": "synonym"
                },
                {
                    "name": "dsRNA adenosine deaminase",
                    "type": "synonym"
                },
                {
                    "name": "dsRNA adeonosine deaminase",
                    "type": "synonym"
                },
                {
                    "name": "interferon-induced protein 4",
                    "type": "synonym"
                },
                {
                    "name": "interferon-inducible protein 4",
                    "type": "synonym"
                },
                {
                    "name": "p136",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ADAR",
                    "type": "recommended"
                },
                {
                    "name": "ADAR1",
                    "type": "synonym"
                },
                {
                    "name": "ADAR",
                    "type": "synonym"
                },
                {
                    "name": "AGS6",
                    "type": "synonym"
                },
                {
                    "name": "DRADA",
                    "type": "synonym"
                },
                {
                    "name": "DSH",
                    "type": "synonym"
                },
                {
                    "name": "DSRAD",
                    "type": "synonym"
                },
                {
                    "name": "G1P1",
                    "type": "synonym"
                },
                {
                    "name": "IFI-4",
                    "type": "synonym"
                },
                {
                    "name": "IFI4",
                    "type": "synonym"
                },
                {
                    "name": "K88DSRBP",
                    "type": "synonym"
                },
                {
                    "name": "P136",
                    "type": "synonym"
                }
            ],
            "record_id": "P55265-1",
            "evidence": [
                {
                    "id": "127400",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/127400"
                },
                {
                    "id": "0060257",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060257"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P55266-1",
            "uniprot_ac": "P55266",
            "uniprot_id": "DSRAD_RAT",
            "refseq_ac": "NP_112268",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Double-stranded RNA-specific adenosine deaminase",
                    "type": "recommended"
                },
                {
                    "name": "3.5.4.37",
                    "type": "synonym"
                },
                {
                    "name": "DRADA",
                    "type": "synonym"
                },
                {
                    "name": "double-stranded RNA-specific adenosine deaminase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Adar",
                    "type": "recommended"
                },
                {
                    "name": "Adar",
                    "type": "synonym"
                },
                {
                    "name": "Dsrad",
                    "type": "synonym"
                }
            ],
            "record_id": "P55266-1",
            "evidence": [
                {
                    "id": "0060257",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060257"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0060257"
}