{
    "disease_id": "DOID:0060060",
    "recommended_name": {
        "id": "DOID:0060060",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060060",
        "name": "non-Hodgkin lymphoma",
        "description": "A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma."
    },
    "synonyms": [
        {
            "id": "MONDO:0011508",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011508",
            "name": "lymphoma, non-Hodgkin, familial",
            "description": ""
        },
        {
            "id": "MONDO:0011508",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011508",
            "name": "lymphoma, follicular, somatic",
            "description": ""
        },
        {
            "id": "MONDO:0011508",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011508",
            "name": "lymphoma, non-Hodgkin",
            "description": ""
        },
        {
            "id": "MONDO:0011508",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011508",
            "name": "lymphoma, non-Hodgkin, familial",
            "description": ""
        },
        {
            "id": "MONDO:0011508",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011508",
            "name": "lymphoma, non-Hodgkin, somatic",
            "description": ""
        },
        {
            "id": "MIM:605027",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/605027",
            "name": "Familial non-Hodgkin lymphoma",
            "description": "Familial non-Hodgkin lymphoma"
        }
    ],
    "children": [
        {
            "id": "DOID:0050744",
            "label": "anaplastic large cell lymphoma",
            "link_status": true,
            "children": []
        },
        {
            "id": "DOID:0081312",
            "label": "T-cell non-Hodgkin lymphoma",
            "link_status": true,
            "children": [
                {
                    "id": "DOID:0050743",
                    "label": "mature T-cell and NK-cell lymphoma",
                    "link_status": false,
                    "children": [
                        {
                            "id": "DOID:0050749",
                            "label": "peripheral T-cell lymphoma",
                            "link_status": true,
                            "children": [
                                {
                                    "id": "DOID:0060061",
                                    "label": "primary cutaneous T-cell non-Hodgkin lymphoma",
                                    "link_status": true,
                                    "children": [
                                        {
                                            "id": "DOID:0070662",
                                            "label": "subcutaneous panniculitis-like T-cell lymphoma",
                                            "link_status": true,
                                            "children": []
                                        },
                                        {
                                            "id": "DOID:8541",
                                            "label": "Sezary's disease",
                                            "link_status": true,
                                            "children": []
                                        },
                                        {
                                            "id": "DOID:8691",
                                            "label": "mycosis fungoides",
                                            "link_status": true,
                                            "children": []
                                        }
                                    ]
                                }
                            ]
                        },
                        {
                            "id": "DOID:0080797",
                            "label": "nasal type extranodal NK/T-cell lymphoma",
                            "link_status": true,
                            "children": []
                        }
                    ]
                },
                {
                    "id": "DOID:5603",
                    "label": "T-cell acute lymphoblastic leukemia",
                    "link_status": true,
                    "children": [
                        {
                            "id": "DOID:0050523",
                            "label": "adult T-cell leukemia/lymphoma",
                            "link_status": true,
                            "children": []
                        },
                        {
                            "id": "DOID:5602",
                            "label": "T-cell adult acute lymphocytic leukemia",
                            "link_status": true,
                            "children": []
                        }
                    ]
                },
                {
                    "id": "DOID:9953",
                    "label": "acute biphenotypic leukemia",
                    "link_status": true,
                    "children": []
                }
            ]
        },
        {
            "id": "DOID:707",
            "label": "B-cell lymphoma",
            "link_status": true,
            "children": [
                {
                    "id": "DOID:0050746",
                    "label": "mantle cell lymphoma",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0050748",
                    "label": "marginal zone lymphoma",
                    "link_status": true,
                    "children": [
                        {
                            "id": "DOID:0050750",
                            "label": "splenic marginal zone lymphoma",
                            "link_status": true,
                            "children": []
                        },
                        {
                            "id": "DOID:0050909",
                            "label": "extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue",
                            "link_status": true,
                            "children": []
                        }
                    ]
                },
                {
                    "id": "DOID:0050873",
                    "label": "follicular lymphoma",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0060901",
                    "label": "lymphoplasmacytic lymphoma",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0081452",
                    "label": "large B-cell lymphoma",
                    "link_status": false,
                    "children": [
                        {
                            "id": "DOID:0050745",
                            "label": "diffuse large B-cell lymphoma",
                            "link_status": true,
                            "children": []
                        }
                    ]
                },
                {
                    "id": "DOID:706",
                    "label": "mature B-cell neoplasm",
                    "link_status": false,
                    "children": [
                        {
                            "id": "DOID:6536",
                            "label": "plasma cell neoplasm",
                            "link_status": false,
                            "children": [
                                {
                                    "id": "DOID:3721",
                                    "label": "plasmacytoma",
                                    "link_status": true,
                                    "children": []
                                },
                                {
                                    "id": "DOID:9513",
                                    "label": "plasma cell leukemia",
                                    "link_status": true,
                                    "children": []
                                }
                            ]
                        },
                        {
                            "id": "DOID:8584",
                            "label": "Burkitt lymphoma",
                            "link_status": true,
                            "children": []
                        }
                    ]
                }
            ]
        }
    ],
    "id_list": [
        "DOID:0050749",
        "DOID:8541",
        "DOID:0050745",
        "DOID:0050523",
        "DOID:8584",
        "DOID:0081312",
        "DOID:0081452",
        "DOID:0050873",
        "DOID:706",
        "DOID:0060060",
        "DOID:5603",
        "DOID:0070662",
        "DOID:0050750",
        "DOID:3721",
        "DOID:0050909",
        "DOID:707",
        "DOID:8691",
        "DOID:0060061",
        "DOID:9513",
        "DOID:9953",
        "DOID:0050748",
        "DOID:0050744",
        "DOID:0060901",
        "DOID:0050746",
        "DOID:0080797",
        "DOID:6536",
        "DOID:0050743",
        "DOID:5602"
    ],
    "unlinked_id_list": [
        "DOID:0081452",
        "DOID:6536",
        "DOID:706",
        "DOID:0050743"
    ],
    "crossref": [
        {
            "id": "DOID:0060060",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060060",
            "categories": []
        },
        {
            "id": "MONDO:0011508",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0011508",
            "categories": []
        },
        {
            "id": "MIM:605027",
            "database": "MIM",
            "url": "https://www.omim.org/entry/605027",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q90459-1",
            "uniprot_ac": "Q90459",
            "uniprot_id": "CCND1_DANRE",
            "refseq_ac": "NP_571100",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "G1/S-specific cyclin-D1",
                    "type": "recommended"
                },
                {
                    "name": "G1/S-specific cyclin-D1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ccnd1",
                    "type": "recommended"
                },
                {
                    "name": "cb161",
                    "type": "synonym"
                },
                {
                    "name": "ccnd1",
                    "type": "synonym"
                },
                {
                    "name": "cycd1",
                    "type": "synonym"
                },
                {
                    "name": "etID37810.7",
                    "type": "synonym"
                },
                {
                    "name": "fb52e01",
                    "type": "synonym"
                },
                {
                    "name": "fc45c08",
                    "type": "synonym"
                },
                {
                    "name": "fc83a12",
                    "type": "synonym"
                },
                {
                    "name": "id:ibd1198",
                    "type": "synonym"
                },
                {
                    "name": "wu:fb52e01",
                    "type": "synonym"
                },
                {
                    "name": "wu:fc45c08",
                    "type": "synonym"
                },
                {
                    "name": "wu:fc83a12",
                    "type": "synonym"
                }
            ],
            "record_id": "Q90459-1",
            "evidence": [
                {
                    "id": "0060060",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060060"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "E7F8A6-1",
            "uniprot_ac": "E7F8A6",
            "uniprot_id": "E7F8A6_DANRE",
            "refseq_ac": "XP_002660738",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "B-cell lymphoma/leukemia 10",
                    "type": "recommended"
                },
                {
                    "name": "B-cell CLL/lymphoma 10",
                    "type": "synonym"
                },
                {
                    "name": "B-cell lymphoma/leukemia 10 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "bcl10",
                    "type": "recommended"
                },
                {
                    "name": "bcl10",
                    "type": "synonym"
                }
            ],
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                    "id": "0060060",
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            "uniprot_canonical_ac": "E7EXV8-1",
            "uniprot_ac": "E7EXV8",
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                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Caspase-8",
                    "type": "synonym"
                },
                {
                    "name": "caspase-8",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "casp10",
                    "type": "recommended"
                },
                {
                    "name": "casp10",
                    "type": "synonym"
                }
            ],
            "record_id": "E7EXV8-1",
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                {
                    "id": "0060060",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0060060"
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        {
            "uniprot_canonical_ac": "A0A8M9QAE5-1",
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                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Epoxide hydrolase",
                    "type": "recommended"
                },
                {
                    "name": "3.3.2.9",
                    "type": "synonym"
                },
                {
                    "name": "epoxide hydrolase 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ephx5",
                    "type": "recommended"
                },
                {
                    "name": "ephx5",
                    "type": "synonym"
                }
            ],
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                    "id": "0060060",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0060060"
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        {
            "uniprot_canonical_ac": "A0A8M2BCW4-1",
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                {
                    "name": "Danio rerio",
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                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1",
                    "type": "synonym"
                },
                {
                    "name": "mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "malt1",
                    "type": "recommended"
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                {
                    "name": "malt1",
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                    "id": "0060060",
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            "uniprot_canonical_ac": "F1QL52-1",
            "uniprot_ac": "F1QL52",
            "uniprot_id": "F1QL52_DANRE",
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                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Histone-lysine N-methyltransferase",
                    "type": "recommended"
                },
                {
                    "name": "2.1.1.364",
                    "type": "synonym"
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                {
                    "name": "histone-lysine N-methyltransferase 2A isoform X1",
                    "type": "synonym"
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            ],
            "gene_names": [
                {
                    "name": "kmt2a",
                    "type": "recommended"
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                {
                    "name": "im:7148357",
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                {
                    "name": "kmt2a",
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                {
                    "name": "mll",
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                    "id": "0060060",
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            "uniprot_canonical_ac": "F1RE28-1",
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                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Methionine synthase reductase",
                    "type": "recommended"
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                {
                    "name": "1.16.1.8",
                    "type": "synonym"
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                {
                    "name": "Aquacobalamin reductase",
                    "type": "synonym"
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                {
                    "name": "methionine synthase reductase",
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            ],
            "gene_names": [
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                    "name": "mtrr",
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                    "id": "0060060",
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                    "common_name": "Zebrafish",
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                {
                    "name": "DNA repair and recombination protein RAD54B",
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                {
                    "name": "rad54b",
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                    "name": "rad54b",
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                    "id": "0060060",
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                    "name": "rad54l",
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            ],
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                    "id": "0060060",
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                    "id": "0060060",
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                {
                    "name": "Cyclin D, isoform F",
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                }
            ],
            "protein_names": [
                {
                    "name": "Sphingosine 1-phosphate receptor 2",
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                {
                    "name": "CTD-2369P2.2",
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                },
                {
                    "name": "Endothelial differentiation G protein-coupled receptor 5",
                    "type": "synonym"
                },
                {
                    "name": "S1P receptor 2",
                    "type": "synonym"
                },
                {
                    "name": "S1P receptor EDG5",
                    "type": "synonym"
                },
                {
                    "name": "S1P receptor Edg-5",
                    "type": "synonym"
                },
                {
                    "name": "S1P2",
                    "type": "synonym"
                },
                {
                    "name": "Sphingosine 1-phosphate receptor Edg-5",
                    "type": "synonym"
                },
                {
                    "name": "deafness, autosomal recessive 68",
                    "type": "synonym"
                },
                {
                    "name": "endothelial differentiation G-protein coupled receptor 5",
                    "type": "synonym"
                },
                {
                    "name": "endothelial differentiation, sphingolipid G-protein-coupled receptor, 5",
                    "type": "synonym"
                },
                {
                    "name": "sphingosine 1-phosphate receptor 2",
                    "type": "synonym"
                },
                {
                    "name": "sphingosine 1-phosphate receptor Edg-5",
                    "type": "synonym"
                }
            ],
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                    "name": "S1PR2",
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                    "name": "AGR16",
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                {
                    "name": "DFNB68",
                    "type": "synonym"
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                {
                    "name": "EDG-5",
                    "type": "synonym"
                },
                {
                    "name": "EDG5",
                    "type": "synonym"
                },
                {
                    "name": "Gpcr13",
                    "type": "synonym"
                },
                {
                    "name": "H218",
                    "type": "synonym"
                },
                {
                    "name": "LPB2",
                    "type": "synonym"
                },
                {
                    "name": "S1P2",
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                },
                {
                    "name": "S1PR2",
                    "type": "synonym"
                }
            ],
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                    "id": "0060060",
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            ]
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                {
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                    "type": "synonym"
                },
                {
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                },
                {
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                },
                {
                    "name": "metastasis suppressor 1",
                    "type": "synonym"
                },
                {
                    "name": "metastasis suppressor YGL-1",
                    "type": "synonym"
                },
                {
                    "name": "metastasis suppressor protein 1",
                    "type": "synonym"
                },
                {
                    "name": "missing in metastasis protein",
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                {
                    "name": "protein MTSS 1 isoform 1",
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                {
                    "name": "protein MTSS 1",
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                }
            ],
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                    "name": "MIMA",
                    "type": "synonym"
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                {
                    "name": "MIMB",
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                {
                    "name": "MIM",
                    "type": "synonym"
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                {
                    "name": "MTSS1",
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                }
            ]
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            ],
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                {
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                    "name": "P1",
                    "type": "synonym"
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                    "name": "PFP",
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                },
                {
                    "name": "cytolysin",
                    "type": "synonym"
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                {
                    "name": "lymphocyte pore-forming protein",
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                },
                {
                    "name": "perforin 1 (pore forming protein)",
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                {
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                }
            ],
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                },
                {
                    "name": "HPLH2",
                    "type": "synonym"
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                {
                    "name": "P1",
                    "type": "synonym"
                },
                {
                    "name": "PFP",
                    "type": "synonym"
                },
                {
                    "name": "PRF1",
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                }
            ],
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                    "id": "0060060",
                    "database": "AGR",
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                }
            ]
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            "uniprot_canonical_ac": "Q9NX78-1",
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                    "taxid": 9606,
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                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                    "name": "Protein O-mannosyl-transferase TMEM260",
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                },
                {
                    "name": "2.4.1.109",
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                },
                {
                    "name": "Transmembrane protein 260",
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                {
                    "name": "UPF0679 protein C14orf101",
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                {
                    "name": "protein O-mannosyl-transferase TMEM260 precursor",
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                {
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            ],
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                {
                    "name": "TMEM260",
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                    "name": "SHDRA",
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                {
                    "name": "TMEM260",
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            ],
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                    "id": "0060060",
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            ]
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            ],
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                {
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                },
                {
                    "name": "3.1.8.1",
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                {
                    "name": "A-esterase 1",
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                },
                {
                    "name": "Aromatic esterase 1",
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                {
                    "name": "K-45",
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                {
                    "name": "PON 1",
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                {
                    "name": "Serum aryldialkylphosphatase 1",
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                },
                {
                    "name": "aromatic esterase 1",
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                },
                {
                    "name": "arylesterase 1",
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                },
                {
                    "name": "arylesterase B-type",
                    "type": "synonym"
                },
                {
                    "name": "esterase A",
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                },
                {
                    "name": "paraoxonase B-type",
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                {
                    "name": "serum aryldiakylphosphatase",
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                {
                    "name": "serum aryldialkylphosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "serum paraoxonase/arylesterase 1",
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            ],
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                },
                {
                    "name": "MVCD5",
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                {
                    "name": "PON1",
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                },
                {
                    "name": "PON",
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                    "id": "0060060",
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                {
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                {
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                    "id": "0060060",
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            ]
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                {
                    "name": "AqCbl reductase",
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                {
                    "name": "Aquacobalamin reductase",
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                },
                {
                    "name": "MSR",
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                },
                {
                    "name": "[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing)",
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                {
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                {
                    "name": "aquacobalamin reductase",
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                {
                    "name": "methionine synthase reductase, mitochondrial",
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                {
                    "name": "methionine synthase reductase",
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                {
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                {
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            ],
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                    "id": "0060060",
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            ],
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                {
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                {
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                {
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            ],
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                {
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                    "id": "0060060",
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
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                {
                    "name": "HTRX",
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                {
                    "name": "KMT2A",
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                {
                    "name": "MLL1A",
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                },
                {
                    "name": "MLL1",
                    "type": "synonym"
                },
                {
                    "name": "MLL",
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                {
                    "name": "TRX1",
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                {
                    "name": "WDSTS",
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                    "id": "0060060",
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                    "name": "Homo sapiens",
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            ],
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                    "name": "Low affinity immunoglobulin gamma Fc region receptor II-a",
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                {
                    "name": "Fc fragment of IgG receptor IIa",
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                },
                {
                    "name": "Fc fragment of IgG, low affinity IIa, receptor (CD32)",
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                {
                    "name": "Fc gamma receptor RIIa3",
                    "type": "synonym"
                },
                {
                    "name": "Fc-gamma RII-a",
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                {
                    "name": "Fc-gamma-RIIa",
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                {
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                {
                    "name": "IgG Fc receptor II-a",
                    "type": "synonym"
                },
                {
                    "name": "Immunoglobulin G Fc receptor II",
                    "type": "synonym"
                },
                {
                    "name": "fc-gamma-RIIa",
                    "type": "synonym"
                },
                {
                    "name": "fcRII-a",
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                {
                    "name": "igG Fc receptor II-a",
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                },
                {
                    "name": "low affinity immunoglobulin gamma Fc region receptor II-a isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "low affinity immunoglobulin gamma Fc region receptor II-a",
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}
