{
    "disease_id": "DOID:0051026",
    "recommended_name": {
        "id": "DOID:0051026",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0051026",
        "name": "visceral heterotaxy 12",
        "description": "A visceral heterotaxy that is characterized by defects in the asymmetric positioning of visceral organs across the left-right axis, known as laterality defects and that has_material_basis_in homozygous or compound heterozygous mutation in the CIROP gene on chromosome 14q11."
    },
    "synonyms": [
        {
            "id": "MONDO:0859222",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0859222",
            "name": "heterotaxy, visceral, 12, autosomal",
            "description": ""
        },
        {
            "id": "MIM:619702",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/619702",
            "name": "Heterotaxy, visceral, 12, autosomal",
            "description": "Heterotaxy, visceral, 12, autosomal"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0051026"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0051026",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0051026",
            "categories": []
        },
        {
            "id": "MONDO:0859222",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0859222",
            "categories": []
        },
        {
            "id": "MIM:619702",
            "database": "MIM",
            "url": "https://www.omim.org/entry/619702",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A286YEC0-1",
            "uniprot_ac": "A0A286YEC0",
            "uniprot_id": "CIROP_MOUSE",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ciliated left-right organizer metallopeptidase",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.-",
                    "type": "synonym"
                },
                {
                    "name": "Leishmanolysin-like peptidase 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Cirop",
                    "type": "recommended"
                },
                {
                    "name": "Gm29776",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A286YEC0-1",
            "evidence": [
                {
                    "id": "0051026",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0051026"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A1B0GTW7-1",
            "uniprot_ac": "A0A1B0GTW7",
            "uniprot_id": "CIROP_HUMAN",
            "refseq_ac": "NP_001341569",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Ciliated left-right organizer metallopeptidase",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.-",
                    "type": "synonym"
                },
                {
                    "name": "Leishmanolysin-like peptidase 2",
                    "type": "synonym"
                },
                {
                    "name": "ciliated left-right organizer metallopeptidase isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "leishmanolysin homolog",
                    "type": "synonym"
                },
                {
                    "name": "leishmanolysin like peptidase 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CIROP",
                    "type": "recommended"
                },
                {
                    "name": "CIROP",
                    "type": "synonym"
                },
                {
                    "name": "HTX12",
                    "type": "synonym"
                },
                {
                    "name": "LMLN2",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A1B0GTW7-1",
            "evidence": [
                {
                    "id": "619702",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/619702"
                },
                {
                    "id": "0051026",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0051026"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2JX27-1",
            "uniprot_ac": "A0A0G2JX27",
            "uniprot_id": "A0A0G2JX27_RAT",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leishmanolysin-like peptidase",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.-",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Cirop",
                    "type": "recommended"
                }
            ],
            "record_id": "A0A0G2JX27-1",
            "evidence": [
                {
                    "id": "0051026",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0051026"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0051026"
}