{
    "disease_id": "DOID:0050860",
    "recommended_name": {
        "id": "DOID:0050860",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0050860",
        "name": "colorectal adenoma",
        "description": "An intestinal benign neoplasm that has_material_basis_in epithelial tissue of glandular origin and is located_in colon and located_in rectum."
    },
    "synonyms": [],
    "children": [],
    "id_list": [
        "DOID:0050860"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0050860",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050860",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "F1RE08-1",
            "uniprot_ac": "F1RE08",
            "uniprot_id": "PTGIS_DANRE",
            "refseq_ac": "NP_001104630",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Prostacyclin synthase",
                    "type": "recommended"
                },
                {
                    "name": "4.2.1.152",
                    "type": "synonym"
                },
                {
                    "name": "5.3.99.4",
                    "type": "synonym"
                },
                {
                    "name": "Hydroperoxy icosatetraenoate dehydratase",
                    "type": "synonym"
                },
                {
                    "name": "PGIS",
                    "type": "synonym"
                },
                {
                    "name": "Prostaglandin I2 synthase",
                    "type": "synonym"
                },
                {
                    "name": "hydroperoxy icosatetraenoate dehydratase",
                    "type": "synonym"
                },
                {
                    "name": "prostacyclin synthase",
                    "type": "synonym"
                },
                {
                    "name": "prostaglandin I2 (prostacyclin) synthase like",
                    "type": "synonym"
                },
                {
                    "name": "prostaglandin I2 synthase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ptgis",
                    "type": "recommended"
                },
                {
                    "name": "PGIS",
                    "type": "synonym"
                },
                {
                    "name": "ptgisl",
                    "type": "synonym"
                },
                {
                    "name": "ptgis",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
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            "glycoprotein": "no",
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                    "name": "Danio rerio",
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                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
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                }
            ],
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                {
                    "name": "Mitogen-activated protein kinase 8",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.24",
                    "type": "synonym"
                },
                {
                    "name": "MAP kinase 8",
                    "type": "synonym"
                },
                {
                    "name": "MAPK 8",
                    "type": "synonym"
                },
                {
                    "name": "Stress-activated protein kinase JNK1",
                    "type": "synonym"
                },
                {
                    "name": "c-Jun N-terminal kinase 1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase 8",
                    "type": "synonym"
                },
                {
                    "name": "stress-activated protein kinase JNK1",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "mapk8",
                    "type": "recommended"
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                {
                    "name": "JNK1",
                    "type": "synonym"
                },
                {
                    "name": "JNK",
                    "type": "synonym"
                },
                {
                    "name": "jnk1a-1",
                    "type": "synonym"
                },
                {
                    "name": "jnk1b",
                    "type": "synonym"
                },
                {
                    "name": "jnk1",
                    "type": "synonym"
                },
                {
                    "name": "mapk8b",
                    "type": "synonym"
                },
                {
                    "name": "mapk8",
                    "type": "synonym"
                },
                {
                    "name": "zgc:112379",
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                }
            ],
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                    "id": "0050860",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
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                    "glygen_name": "Zebrafish",
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                }
            ],
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                {
                    "name": "Histone-lysine N-methyltransferase EZH2",
                    "type": "recommended"
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                {
                    "name": "2.1.1.356",
                    "type": "synonym"
                },
                {
                    "name": "Enhancer of zeste homolog 2",
                    "type": "synonym"
                },
                {
                    "name": "enhancer of zeste homolog 2",
                    "type": "synonym"
                },
                {
                    "name": "eyes absent homolog 2",
                    "type": "synonym"
                },
                {
                    "name": "histone-lysine N-methyltransferase EZH2",
                    "type": "synonym"
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            ],
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                    "name": "ezh2",
                    "type": "recommended"
                },
                {
                    "name": "eya2",
                    "type": "synonym"
                },
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                    "name": "ezh2",
                    "type": "synonym"
                },
                {
                    "name": "im:7149338",
                    "type": "synonym"
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                {
                    "name": "zgc:136376",
                    "type": "synonym"
                },
                {
                    "name": "zgc:152758",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
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                }
            ]
        },
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                    "name": "Danio rerio",
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                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
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                }
            ],
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                {
                    "name": "RING-type E3 ubiquitin transferase",
                    "type": "recommended"
                },
                {
                    "name": "2.3.2.27",
                    "type": "synonym"
                },
                {
                    "name": "baculoviral IAP repeat-containing protein 7 isoform 1",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "birc7",
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                {
                    "name": "birc7",
                    "type": "synonym"
                },
                {
                    "name": "zgc:165605",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8M9P0S1-1",
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                {
                    "name": "Danio rerio",
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                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
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                }
            ],
            "protein_names": [
                {
                    "name": "Protein c-Fos",
                    "type": "synonym"
                },
                {
                    "name": "protein c-Fos",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "fosaa",
                    "type": "recommended"
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                {
                    "name": "fosaa",
                    "type": "synonym"
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                {
                    "id": "0050860",
                    "database": "AGR",
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                }
            ]
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                    "name": "Danio rerio",
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                    "glygen_name": "Zebrafish",
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                }
            ],
            "protein_names": [
                {
                    "name": "Glutathione peroxidase",
                    "type": "recommended"
                },
                {
                    "name": "glutathione peroxidase 2 (gastrointestinal)",
                    "type": "synonym"
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                {
                    "name": "glutathione peroxidase 2",
                    "type": "synonym"
                }
            ],
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                    "name": "gpx2",
                    "type": "recommended"
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                    "name": "gpx2",
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                {
                    "name": "si:ch73-199k24.2",
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                {
                    "id": "0050860",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
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                }
            ],
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                {
                    "name": "Glutathione peroxidase",
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                {
                    "name": "glutathione peroxidase 3 (plasma)",
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                {
                    "name": "glutathione peroxidase 3 precursor",
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                }
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                    "name": "gpx3",
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                    "name": "gpx3",
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                    "id": "0050860",
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            ],
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                {
                    "name": "Mothers against decapentaplegic homolog",
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                    "name": "MAD homolog",
                    "type": "synonym"
                },
                {
                    "name": "Mothers against DPP homolog",
                    "type": "synonym"
                },
                {
                    "name": "SMAD family member",
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                {
                    "name": "mothers against decapentaplegic homolog 4a isoform X1",
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                    "name": "smad4a",
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                    "name": "madh4",
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                    "name": "zmp:0000000768",
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                    "id": "0050860",
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                }
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                    "name": "Selenoprotein S",
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                    "name": "SelS",
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                {
                    "name": "VCP-interacting membrane protein",
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                {
                    "name": "VCP-interacting membrane selenoprotein",
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                    "name": "selenoprotein S",
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                {
                    "name": "zgc:136970",
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                    "id": "0050860",
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                    "name": "Selenide, water dikinase 3",
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                    "name": "Selenophosphate synthetase 3",
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                    "name": "selenophosphate synthetase 2",
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                }
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                    "name": "protein patched homolog 1",
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                    "id": "0050860",
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                }
            ],
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                    "name": "RAF proto-oncogene serine/threonine-protein kinase",
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                    "name": "2.7.11.1",
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                    "name": "RAF proto-oncogene serine/threonine-protein kinase",
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                {
                    "name": "Raf-1",
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                    "name": "v-raf-1 murine leukemia viral oncogene homolog 1b",
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                    "id": "0050860",
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            ],
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                {
                    "name": "cyp12a4",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q7KR10-1",
            "uniprot_ac": "Q7KR10",
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            "refseq_ac": "NP_995812",
            "glycoprotein": "no",
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                {
                    "name": "Drosophila melanogaster",
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                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Probable cytochrome P450 12d1 distal, mitochondrial",
                    "type": "recommended"
                },
                {
                    "name": "1.14.-.-",
                    "type": "synonym"
                },
                {
                    "name": "CG33503-PA",
                    "type": "synonym"
                },
                {
                    "name": "CYPXIID1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d1-d-PA",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450 12d1 distal",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450-12d1",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Cyp12d1-d",
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                },
                {
                    "name": "12D1",
                    "type": "synonym"
                },
                {
                    "name": "12d1",
                    "type": "synonym"
                },
                {
                    "name": "CG18239",
                    "type": "synonym"
                },
                {
                    "name": "CG18240",
                    "type": "synonym"
                },
                {
                    "name": "CG33503",
                    "type": "synonym"
                },
                {
                    "name": "CT26082",
                    "type": "synonym"
                },
                {
                    "name": "CYP12A2",
                    "type": "synonym"
                },
                {
                    "name": "CYP12D1",
                    "type": "synonym"
                },
                {
                    "name": "CYP12d1-d",
                    "type": "synonym"
                },
                {
                    "name": "Cyp 12d1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d1-d",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d2",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG33503",
                    "type": "synonym"
                },
                {
                    "name": "cyp12d1-d",
                    "type": "synonym"
                },
                {
                    "name": "cyp12d1",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P82712-1",
            "uniprot_ac": "P82712",
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                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
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                }
            ],
            "protein_names": [
                {
                    "name": "Probable cytochrome P450 12d1 proximal, mitochondrial",
                    "type": "recommended"
                },
                {
                    "name": "1.14.-.-",
                    "type": "synonym"
                },
                {
                    "name": "CG30489-PB",
                    "type": "synonym"
                },
                {
                    "name": "CYPXIID1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d1-p-PB",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450 12d1 proximal, isoform B",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450-12d1",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Cyp12d1-p",
                    "type": "recommended"
                },
                {
                    "name": "12D1",
                    "type": "synonym"
                },
                {
                    "name": "12d1",
                    "type": "synonym"
                },
                {
                    "name": "CG18240",
                    "type": "synonym"
                },
                {
                    "name": "CG30489",
                    "type": "synonym"
                },
                {
                    "name": "CYP12A2",
                    "type": "synonym"
                },
                {
                    "name": "CYP12D1",
                    "type": "synonym"
                },
                {
                    "name": "CYP12d1-p",
                    "type": "synonym"
                },
                {
                    "name": "Cyp 12d1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d1-p",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp12d",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG30489",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG30489",
                    "type": "synonym"
                },
                {
                    "name": "cyp12d1-p",
                    "type": "synonym"
                },
                {
                    "name": "cyp12d1",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9V5L3-1",
            "uniprot_ac": "Q9V5L3",
            "uniprot_id": "C49A1_DROME",
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            "glycoprotein": "no",
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                {
                    "name": "Drosophila melanogaster",
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                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Probable cytochrome P450 49a1",
                    "type": "recommended"
                },
                {
                    "name": "1.14.-.-",
                    "type": "synonym"
                },
                {
                    "name": "CG18377-PE",
                    "type": "synonym"
                },
                {
                    "name": "CYPXLIXA1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp49a1-PE",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450 49a1, isoform E",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Cyp49a1",
                    "type": "recommended"
                },
                {
                    "name": "49a1",
                    "type": "synonym"
                },
                {
                    "name": "CG12894",
                    "type": "synonym"
                },
                {
                    "name": "CG18377",
                    "type": "synonym"
                },
                {
                    "name": "Cyp49A1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp49a1p",
                    "type": "synonym"
                },
                {
                    "name": "Cyp49a1",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG18377",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG18377",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9V6D6-1",
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                {
                    "name": "Drosophila melanogaster",
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                }
            ],
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                {
                    "name": "Probable cytochrome P450 301a1, mitochondrial",
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                },
                {
                    "name": "1.14.-.-",
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                },
                {
                    "name": "CG8587-PA",
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                },
                {
                    "name": "CYPCCCIA1",
                    "type": "synonym"
                },
                {
                    "name": "Cyp301a1-PA",
                    "type": "synonym"
                },
                {
                    "name": "cytochrome P450 301a1",
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                },
                {
                    "name": "cytochrome P450",
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                }
            ],
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                {
                    "name": "Cyp301a1",
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                },
                {
                    "name": "301a1",
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                },
                {
                    "name": "CG8587",
                    "type": "synonym"
                },
                {
                    "name": "Cyp301A1",
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                },
                {
                    "name": "Cyp301a1",
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                },
                {
                    "name": "Dmel\\CG8587",
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                },
                {
                    "name": "cutl",
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                }
            ],
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                {
                    "id": "0050860",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
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                {
                    "name": "Drosophila melanogaster",
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                }
            ],
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                {
                    "name": "Probable cytochrome P450 12e1, mitochondrial",
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                },
                {
                    "name": "CG14680-PC",
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                },
                {
                    "name": "CYPXIIE1",
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                },
                {
                    "name": "Cyp12e1-PC",
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                },
                {
                    "name": "cytochrome P450 12e1",
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                }
            ],
            "gene_names": [
                {
                    "name": "Cyp12e1",
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                    "name": "12e1",
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                },
                {
                    "name": "CG14680",
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                },
                {
                    "name": "Cyp12E1",
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                },
                {
                    "name": "Cyp12e1",
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                },
                {
                    "name": "Cyp12e",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG14680",
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                }
            ],
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                {
                    "id": "0050860",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P92208-1",
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            "uniprot_id": "JNK_DROME",
            "refseq_ac": "NP_001162930",
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                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
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                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Stress-activated protein kinase JNK",
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                },
                {
                    "name": "2.7.11.24",
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                },
                {
                    "name": "CG5680-PF",
                    "type": "synonym"
                },
                {
                    "name": "JNK",
                    "type": "synonym"
                },
                {
                    "name": "JUN kinase",
                    "type": "synonym"
                },
                {
                    "name": "Jun N-terminal kinase",
                    "type": "synonym"
                },
                {
                    "name": "Jun NH2-terminal kinase",
                    "type": "synonym"
                },
                {
                    "name": "Jun-N terminal kinase",
                    "type": "synonym"
                },
                {
                    "name": "Jun-kinase",
                    "type": "synonym"
                },
                {
                    "name": "Protein basket",
                    "type": "synonym"
                },
                {
                    "name": "basket, isoform F",
                    "type": "synonym"
                },
                {
                    "name": "basket",
                    "type": "synonym"
                },
                {
                    "name": "bsk-PF",
                    "type": "synonym"
                },
                {
                    "name": "c-Jun N-terminal kinase",
                    "type": "synonym"
                },
                {
                    "name": "c-Jun aminoterminal kinase",
                    "type": "synonym"
                },
                {
                    "name": "c-Jun-N-terminal kinase",
                    "type": "synonym"
                },
                {
                    "name": "dJNK",
                    "type": "synonym"
                },
                {
                    "name": "pJNK",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "bsk",
                    "type": "recommended"
                },
                {
                    "name": "BSK",
                    "type": "synonym"
                },
                {
                    "name": "Basket",
                    "type": "synonym"
                },
                {
                    "name": "Bsk",
                    "type": "synonym"
                },
                {
                    "name": "CG5680",
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                },
                {
                    "name": "D-JNK",
                    "type": "synonym"
                },
                {
                    "name": "D-junk",
                    "type": "synonym"
                },
                {
                    "name": "DBSK/JNK",
                    "type": "synonym"
                },
                {
                    "name": "DJNK/bsk",
                    "type": "synonym"
                },
                {
                    "name": "DJNK",
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                },
                {
                    "name": "DmJNK",
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                },
                {
                    "name": "Dmel\\CG5680",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG5680",
                    "type": "synonym"
                },
                {
                    "name": "JAK",
                    "type": "synonym"
                },
                {
                    "name": "JNK/SAPK",
                    "type": "synonym"
                },
                {
                    "name": "JNK",
                    "type": "synonym"
                },
                {
                    "name": "Jak",
                    "type": "synonym"
                },
                {
                    "name": "Jnk",
                    "type": "synonym"
                },
                {
                    "name": "Junk",
                    "type": "synonym"
                },
                {
                    "name": "P-JNK",
                    "type": "synonym"
                },
                {
                    "name": "SAPK/JNK",
                    "type": "synonym"
                },
                {
                    "name": "SAPKa",
                    "type": "synonym"
                },
                {
                    "name": "SAPK",
                    "type": "synonym"
                },
                {
                    "name": "bsk/JNK",
                    "type": "synonym"
                },
                {
                    "name": "bsk",
                    "type": "synonym"
                },
                {
                    "name": "dJNK",
                    "type": "synonym"
                },
                {
                    "name": "dJnk",
                    "type": "synonym"
                },
                {
                    "name": "dNJNK",
                    "type": "synonym"
                },
                {
                    "name": "jnk (bsk)",
                    "type": "synonym"
                },
                {
                    "name": "jnk",
                    "type": "synonym"
                },
                {
                    "name": "p-JNK",
                    "type": "synonym"
                },
                {
                    "name": "pJNK",
                    "type": "synonym"
                }
            ],
            "record_id": "P92208-1",
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                {
                    "id": "0050860",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P42124-1",
            "uniprot_ac": "P42124",
            "uniprot_id": "EZ_DROME",
            "refseq_ac": "NP_001137932",
            "glycoprotein": "no",
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                {
                    "name": "Drosophila melanogaster",
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                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Histone-lysine N-methyltransferase E(z)",
                    "type": "recommended"
                },
                {
                    "name": "2.1.1.356",
                    "type": "synonym"
                },
                {
                    "name": "CG6502-PB",
                    "type": "synonym"
                },
                {
                    "name": "E(z)-PB",
                    "type": "synonym"
                },
                {
                    "name": "Lysine N-methyltransferase 6",
                    "type": "synonym"
                },
                {
                    "name": "Protein enhancer of zeste",
                    "type": "synonym"
                },
                {
                    "name": "enhancer of zeste, isoform B",
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                },
                {
                    "name": "enhancer of zeste",
                    "type": "synonym"
                },
                {
                    "name": "enhancer of zest",
                    "type": "synonym"
                },
                {
                    "name": "enhancer-of-zeste",
                    "type": "synonym"
                },
                {
                    "name": "polycombeotic",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "E(z)",
                    "type": "recommended"
                },
                {
                    "name": "2",
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                },
                {
                    "name": "CG6502",
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                },
                {
                    "name": "Dmel\\CG6502",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG6502",
                    "type": "synonym"
                },
                {
                    "name": "E(Z)",
                    "type": "synonym"
                },
                {
                    "name": "E(z)1",
                    "type": "synonym"
                },
                {
                    "name": "E(z)",
                    "type": "synonym"
                },
                {
                    "name": "EZH1/2",
                    "type": "synonym"
                },
                {
                    "name": "EZH2",
                    "type": "synonym"
                },
                {
                    "name": "EZ",
                    "type": "synonym"
                },
                {
                    "name": "E[z]",
                    "type": "synonym"
                },
                {
                    "name": "Ezh2",
                    "type": "synonym"
                },
                {
                    "name": "Ez",
                    "type": "synonym"
                },
                {
                    "name": "KMT6",
                    "type": "synonym"
                },
                {
                    "name": "Su(z)301",
                    "type": "synonym"
                },
                {
                    "name": "dE(z)",
                    "type": "synonym"
                },
                {
                    "name": "l(3)1902",
                    "type": "synonym"
                },
                {
                    "name": "l(3)67Fa",
                    "type": "synonym"
                },
                {
                    "name": "l(3)B12",
                    "type": "synonym"
                },
                {
                    "name": "l(3)SG17",
                    "type": "synonym"
                },
                {
                    "name": "l(3)ds12",
                    "type": "synonym"
                },
                {
                    "name": "pco/E(z)",
                    "type": "synonym"
                },
                {
                    "name": "pco",
                    "type": "synonym"
                }
            ],
            "record_id": "P42124-1",
            "evidence": [
                {
                    "id": "0050860",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050860"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q24307-1",
            "uniprot_ac": "Q24307",
            "uniprot_id": "DIAP2_DROME",
            "refseq_ac": "NP_477127",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Death-associated inhibitor of apoptosis 2",
                    "type": "recommended"
                },
                {
                    "name": "Apoptosis 2 inhibitor",
                    "type": "synonym"
                },
                {
                    "name": "CG8293-PA",
                    "type": "synonym"
                },
                {
                    "name": "Death-associated inhibitor of apoptosis 2, isoform A",
                    "type": "synonym"
                },
                {
                    "name": "Diap2-PA",
                    "type": "synonym"
                },
                {
                    "name": "IAP homolog A",
                    "type": "synonym"
                },
                {
                    "name": "IAP-like protein",
                    "type": "synonym"
                },
                {
                    "name": "ILP",
                    "type": "synonym"
                },
                {
                    "name": "Inhibitor of apoptosis 2",
                    "type": "synonym"
                },
                {
                    "name": "dILP",
                    "type": "synonym"
                },
                {
                    "name": "drosophila inhibitor of apoptosis 2",
                    "type": "synonym"
                },
                {
                    "name": "drosophila melanogaster inhibitor of apoptosis 2",
                    "type": "synonym"
                },
                {
                    "name": "inhibitor of apoptosis protein 2",
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                    "name": "Diap2",
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                    "name": "CG8293",
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                    "name": "D-IAP2",
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                    "name": "D-iap2",
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                    "name": "DIAP-2",
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                    "name": "DIAP1",
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                {
                    "name": "DIAP2",
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                    "name": "DIAPII",
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                {
                    "name": "DIAP",
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                {
                    "name": "DIHA",
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                {
                    "name": "Diap-2",
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                {
                    "name": "Diap2",
                    "type": "synonym"
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                {
                    "name": "Diap",
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                {
                    "name": "Diha",
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                {
                    "name": "Dmel\\CG8293",
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                    "name": "IAP2",
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                    "name": "IAP",
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                },
                {
                    "name": "Iap2",
                    "type": "synonym"
                },
                {
                    "name": "Ilp",
                    "type": "synonym"
                },
                {
                    "name": "dIAP2",
                    "type": "synonym"
                },
                {
                    "name": "dIAP",
                    "type": "synonym"
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                {
                    "name": "dILP",
                    "type": "synonym"
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                {
                    "name": "diap2",
                    "type": "synonym"
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            ],
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                {
                    "id": "0050860",
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            ]
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            ],
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                    "name": "Transcription factor kayak, isoforms A/B/F",
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                    "name": "AP-1",
                    "type": "synonym"
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                {
                    "name": "CG33956-PF",
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                    "name": "Dfos/kayak",
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                {
                    "name": "Dfos",
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                {
                    "name": "Fos-related antigen",
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                {
                    "name": "Fos",
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                {
                    "name": "activator protein 1",
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                {
                    "name": "dFra",
                    "type": "synonym"
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                {
                    "name": "dorsal holes D",
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                {
                    "name": "kay-PF",
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                {
                    "name": "kayak, isoform F",
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                {
                    "name": "kay",
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                    "name": "AP-1",
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                {
                    "name": "AP1",
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                    "name": "Ap1",
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                    "name": "CG15507",
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                    "name": "CG15509",
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                {
                    "name": "CG33956",
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                    "name": "D-Fos",
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                {
                    "name": "D-fos/kay",
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                    "name": "D-fos",
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                {
                    "name": "DFOS",
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                {
                    "name": "DFos",
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                {
                    "name": "DFra",
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                {
                    "name": "DM30",
                    "type": "synonym"
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                {
                    "name": "DM3",
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                    "name": "Dfos",
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                {
                    "name": "Dmel\\CG33956",
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                    "name": "FOS",
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                    "name": "Fos",
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                    "name": "Fra",
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                    "name": "KAY",
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                    "name": "Kay",
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                    "name": "c-Fos",
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                {
                    "name": "c-fos",
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                    "name": "d-Fos",
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                {
                    "name": "d-fos",
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                {
                    "name": "dAP-1",
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                    "name": "dFRA",
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                    "name": "dFos",
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                {
                    "name": "dFra",
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                    "name": "dfos",
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                {
                    "name": "dlhD",
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                    "name": "fbz",
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                {
                    "name": "fos",
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                {
                    "name": "fra",
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                {
                    "name": "kay",
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                    "id": "0050860",
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                    "name": "Jra-PA",
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                {
                    "name": "Jun oncogene",
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                {
                    "name": "Jun related antigen",
                    "type": "synonym"
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                {
                    "name": "Jun-related antigen, isoform A",
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                {
                    "name": "Jun-related antigen",
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                {
                    "name": "Jun",
                    "type": "synonym"
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                {
                    "name": "Transcription factor AP-1 subunit Jra",
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                {
                    "name": "activator protein 1",
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                    "name": "complementation group V",
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                {
                    "name": "dJRA",
                    "type": "synonym"
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                {
                    "name": "dJun",
                    "type": "synonym"
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                {
                    "name": "lethal(2)1A109",
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                {
                    "name": "lethal(2)IA109",
                    "type": "synonym"
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                    "name": "Jra",
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                    "name": "AP-1",
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                    "name": "AP1",
                    "type": "synonym"
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                {
                    "name": "Ap-1",
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                    "name": "Ap1",
                    "type": "synonym"
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                    "name": "CG2275",
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                    "name": "D-Jun",
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                    "name": "D-jun/Jra",
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                {
                    "name": "D-jun",
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                {
                    "name": "D.Jun",
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                    "name": "DJUN",
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                {
                    "name": "DJun",
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                {
                    "name": "DM14",
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                    "name": "Djun",
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                    "name": "Dmel\\CG2275",
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                    "name": "Dmel_CG2275",
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                    "name": "JUN",
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                    "name": "Jra",
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                    "name": "Jun",
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                    "name": "V",
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                    "name": "c-Jun",
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                    "name": "cJun",
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                    "name": "cjun",
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                    "name": "d-JRA",
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                    "name": "d-Jun",
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                    "name": "d-jun",
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                    "name": "dAP-1",
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                    "name": "dJRA",
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                    "name": "dJUN",
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                    "name": "dJra",
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                    "name": "dJun",
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                    "name": "djun",
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                    "name": "dm-Jun",
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                    "name": "jra",
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                    "name": "jun",
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                    "name": "l(2)46Ef",
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                    "name": "l(2)IA109",
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                {
                    "name": "l(2R)IA109",
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                    "id": "0050860",
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                    "name": "MAD homolog",
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                    "name": "Med-PA",
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                {
                    "name": "Mothers against DPP homolog",
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                    "name": "Mothers against decapentaplegic homolog",
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                    "name": "dSMAD4",
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                    "name": "medea, isoform A",
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                    "name": "medea",
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                    "name": "Med",
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                    "name": "med",
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                    "name": "SeS",
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                    "name": "SelD like",
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                    "name": "SelD",
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                    "name": "anon-WO0172774.145",
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                    "name": "anon-WO0172774.146",
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                    "name": "dSPS1",
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                    "name": "dsps1",
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                    "name": "l(2)SH1599",
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                {
                    "name": "l(2)SH2 1599",
                    "type": "synonym"
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                {
                    "name": "l(2)k12303",
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                    "name": "ptf1",
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                {
                    "name": "ptuf1",
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                    "name": "ptuf",
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                {
                    "name": "selD/sps1",
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                {
                    "name": "selD",
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                }
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                    "name": "polehole",
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                    "name": "C110",
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                    "name": "CG2845",
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                    "name": "D-RAF",
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                    "name": "factor XIIIa",
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                {
                    "name": "Deletion target in pancreatic carcinoma 4",
                    "type": "synonym"
                },
                {
                    "name": "MAD homolog 4",
                    "type": "synonym"
                },
                {
                    "name": "Mothers against DPP homolog 4",
                    "type": "synonym"
                },
                {
                    "name": "Mothers against decapentaplegic homolog 4",
                    "type": "synonym"
                },
                {
                    "name": "SMAD 4",
                    "type": "synonym"
                },
                {
                    "name": "SMAD family member 4 isoform a",
                    "type": "synonym"
                },
                {
                    "name": "SMAD, mothers against DPP homolog 4",
                    "type": "synonym"
                },
                {
                    "name": "deleted in pancreatic carcinoma locus 4",
                    "type": "synonym"
                },
                {
                    "name": "deletion target in pancreatic carcinoma 4",
                    "type": "synonym"
                },
                {
                    "name": "hSMAD4",
                    "type": "synonym"
                },
                {
                    "name": "mothers against decapentaplegic, Drosophila, homolog of, 4",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "SMAD4",
                    "type": "recommended"
                },
                {
                    "name": "DPC4",
                    "type": "synonym"
                },
                {
                    "name": "JIP",
                    "type": "synonym"
                },
                {
                    "name": "MADH4",
                    "type": "synonym"
                },
                {
                    "name": "MYHRS",
                    "type": "synonym"
                },
                {
                    "name": "SMAD4",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
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            ]
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        {
            "uniprot_canonical_ac": "P12259-1",
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                {
                    "name": "Homo sapiens",
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                    "common_name": "Human",
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                    "reference_species": "Homo sapiens [9606]"
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            ],
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                {
                    "name": "Coagulation factor V",
                    "type": "recommended"
                },
                {
                    "name": "Activated protein C cofactor",
                    "type": "synonym"
                },
                {
                    "name": "Proaccelerin, labile factor",
                    "type": "synonym"
                },
                {
                    "name": "activated protein c cofactor",
                    "type": "synonym"
                },
                {
                    "name": "coagulation factor V (proaccelerin, labile factor)",
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                },
                {
                    "name": "coagulation factor V jinjiang A2 domain",
                    "type": "synonym"
                },
                {
                    "name": "coagulation factor V preproprotein",
                    "type": "synonym"
                },
                {
                    "name": "factor V Leiden",
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                }
            ],
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                {
                    "name": "F5",
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                {
                    "name": "F5",
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                },
                {
                    "name": "FVL",
                    "type": "synonym"
                },
                {
                    "name": "PCCF",
                    "type": "synonym"
                },
                {
                    "name": "RPRGL1",
                    "type": "synonym"
                },
                {
                    "name": "THPH2",
                    "type": "synonym"
                },
                {
                    "name": "fV",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050860",
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            ]
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        {
            "uniprot_canonical_ac": "P22352-1",
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                {
                    "name": "Homo sapiens",
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                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                {
                    "name": "Glutathione peroxidase 3",
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                {
                    "name": "1.11.1.9",
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                },
                {
                    "name": "Extracellular glutathione peroxidase",
                    "type": "synonym"
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                {
                    "name": "GPx-3",
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                },
                {
                    "name": "GPx-P",
                    "type": "synonym"
                },
                {
                    "name": "GSHPx-3",
                    "type": "synonym"
                },
                {
                    "name": "GSHPx-P",
                    "type": "synonym"
                },
                {
                    "name": "Plasma glutathione peroxidase",
                    "type": "synonym"
                },
                {
                    "name": "extracellular glutathione peroxidase",
                    "type": "synonym"
                },
                {
                    "name": "glutathione peroxidase 3 (plasma)",
                    "type": "synonym"
                },
                {
                    "name": "glutathione peroxidase 3 isoform 2 precursor",
                    "type": "synonym"
                },
                {
                    "name": "plasma glutathione peroxidase",
                    "type": "synonym"
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                {
                    "name": "selenoprotein GPX3",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "GPX3",
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                    "name": "GPX3",
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                {
                    "name": "GPXP",
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                {
                    "name": "GPx-P",
                    "type": "synonym"
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                {
                    "name": "GSHPx-3",
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                {
                    "name": "GSHPx-P",
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                }
            ],
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                {
                    "id": "0050860",
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            ]
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            "uniprot_canonical_ac": "P05412-1",
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                    "name": "Transcription factor Jun",
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                    "name": "AP1",
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                    "name": "Activator protein 1",
                    "type": "synonym"
                },
                {
                    "name": "Jun activation domain binding protein",
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                {
                    "name": "Proto-oncogene c-Jun",
                    "type": "synonym"
                },
                {
                    "name": "Transcription factor AP-1 subunit Jun",
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                },
                {
                    "name": "V-jun avian sarcoma virus 17 oncogene homolog",
                    "type": "synonym"
                },
                {
                    "name": "activator protein 1",
                    "type": "synonym"
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                {
                    "name": "enhancer-binding protein AP1",
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                {
                    "name": "jun oncogene",
                    "type": "synonym"
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                {
                    "name": "p39",
                    "type": "synonym"
                },
                {
                    "name": "proto-oncogene c-Jun",
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                {
                    "name": "proto-oncogene cJun",
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                {
                    "name": "transcription factor AP-1 subunit Jun",
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                {
                    "name": "transcription factor AP-1",
                    "type": "synonym"
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                {
                    "name": "transcription factor Jun",
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                {
                    "name": "v-jun avian sarcoma virus 17 oncogene homolog",
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                {
                    "name": "v-jun sarcoma virus 17 oncogene homolog",
                    "type": "synonym"
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            ],
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                    "name": "JUN",
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                    "name": "AP-1",
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                    "name": "AP1",
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                {
                    "name": "JUN",
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                    "name": "c-Jun",
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                {
                    "name": "cJUN",
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                {
                    "name": "p39",
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                    "id": "0050860",
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                    "name": "2.7.11.24",
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                    "name": "JNK-46",
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                    "name": "JUN N-terminal kinase",
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                    "name": "MAP kinase 8",
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                    "name": "MAPK 8",
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                    "name": "SAPK1c",
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                    "name": "Stress-activated protein kinase 1c",
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                {
                    "name": "Stress-activated protein kinase JNK1",
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                {
                    "name": "c-Jun N-terminal kinase 1",
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                    "name": "mitogen-activated protein kinase 8 isoform beta2",
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                {
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                    "name": "JNK21B1/2",
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                    "name": "JNK",
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                    "name": "MAPK8",
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                    "name": "PRKM8",
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                    "name": "SAPK1C",
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                    "name": "SAPK1c",
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                {
                    "name": "SAPK1",
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                    "id": "0050860",
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                    "name": "GPx-2",
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                {
                    "name": "Glutathione peroxidase-gastrointestinal",
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                    "name": "Glutathione peroxidase-related protein 2",
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                    "name": "gastrointestinal glutathione peroxidase",
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                    "name": "glutathione peroxidase 2 (gastrointestinal)",
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                    "name": "glutathione peroxidase 2",
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                    "name": "glutathione peroxidase-related protein 2",
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                    "name": "phospholipid hydroperoxide glutathione peroxidase GPX2",
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                    "name": "GPRP",
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                    "name": "GSHPX-GI",
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                    "id": "0050860",
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                    "name": "FBJ murine osteosarcoma viral oncogene homolog",
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                {
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                {
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                    "name": "FOS",
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                    "name": "G0S7",
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                    "name": "p55",
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                    "id": "0050860",
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                    "name": "Livin",
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                {
                    "name": "Melanoma inhibitor of apoptosis protein",
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                    "name": "RING finger protein 50",
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                    "name": "kidney inhibitor of apoptosis protein",
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                    "name": "livin inhibitor of apoptosis",
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                    "name": "melanoma inhibitor of apoptosis protein",
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                    "name": "KIAP",
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                    "name": "LIVIN",
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                    "name": "ML-IAP",
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                    "name": "MLIAP",
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                    "name": "PRO21344",
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                    "name": "RNF50",
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                    "id": "0050860",
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                    "name": "Histone-lysine N-methyltransferase EZH2",
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                    "name": "ENX-1",
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                {
                    "name": "Enhancer of zeste homolog 2",
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                {
                    "name": "Lysine N-methyltransferase 6",
                    "type": "synonym"
                },
                {
                    "name": "enhancer of zeste homolog 2",
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                {
                    "name": "histone-lysine N-methyltransferase EZH2 isoform c",
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                {
                    "name": "histone-lysine N-methyltransferase EZH2",
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                {
                    "name": "lysine N-methyltransferase 6",
                    "type": "synonym"
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            ],
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                    "name": "EZH2",
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                {
                    "name": "ENX1",
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                    "name": "EZH2b",
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                {
                    "name": "EZH2",
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                {
                    "name": "KMT6A",
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                {
                    "name": "KMT6",
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                    "name": "WVS2",
                    "type": "synonym"
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                {
                    "name": "WVS",
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                    "id": "0050860",
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                    "name": "4.2.1.152",
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                {
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                {
                    "name": "Hydroperoxy icosatetraenoate dehydratase",
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                {
                    "name": "Prostaglandin I2 synthase",
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                    "name": "S-(hydroxyalkyl)glutathione lyase",
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                {
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                {
                    "name": "glutathione S-aralkyltransferase",
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                {
                    "name": "glutathione S-aryltransferase",
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                {
                    "name": "glutathione S-transferase M1",
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                    "name": "H-B",
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                {
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                {
                    "name": "fatty acid ethyl ester synthase III",
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                {
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                }
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        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0050860"
}