{
    "disease_id": "DOID:0050851",
    "recommended_name": {
        "id": "DOID:0050851",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0050851",
        "name": "glomerulosclerosis",
        "description": "A glomerulonephritis that is characterized by hardening of the glomerulus in the kidney."
    },
    "synonyms": [],
    "children": [
        {
            "id": "DOID:1312",
            "label": "focal segmental glomerulosclerosis",
            "link_status": true,
            "children": [
                {
                    "id": "DOID:0111128",
                    "label": "focal segmental glomerulosclerosis 1",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0111129",
                    "label": "focal segmental glomerulosclerosis 2",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0111130",
                    "label": "focal segmental glomerulosclerosis 5",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0111131",
                    "label": "focal segmental glomerulosclerosis 6",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0111132",
                    "label": "focal segmental glomerulosclerosis 7",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0111133",
                    "label": "focal segmental glomerulosclerosis 8",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0111134",
                    "label": "focal segmental glomerulosclerosis 9",
                    "link_status": true,
                    "children": []
                },
                {
                    "id": "DOID:0112245",
                    "label": "focal segmental glomerulosclerosis 3",
                    "link_status": true,
                    "children": []
                }
            ]
        }
    ],
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    ],
    "unlinked_id_list": [],
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            "id": "DOID:0050851",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050851",
            "categories": []
        }
    ],
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                    "name": "2-acetyl-1-alkylglycerophosphocholine esterase",
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                    "name": "LDL-PLA(2)",
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                {
                    "name": "LDL-associated phospholipase A2",
                    "type": "synonym"
                },
                {
                    "name": "PAF 2-acylhydrolase",
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                {
                    "name": "PAF acetylhydrolase",
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                },
                {
                    "name": "platelet-activating factor acetylhydrolase precursor",
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                {
                    "name": "platelet-activating factor acetylhydrolase",
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                    "name": "Pafah",
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                {
                    "name": "interleukin 1b",
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                {
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                    "id": "0050851",
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                    "name": "Bsp",
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                    "name": "Eta",
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                    "name": "OP",
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                    "name": "Opnl",
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                    "name": "Opn",
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                    "name": "Op",
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                    "name": "Ric",
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                    "type": "synonym"
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                    "name": "Spp1",
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                    "name": "SSL2",
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                {
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                    "name": "dickkopf-1 like",
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                },
                {
                    "name": "dickkopf-like protein 1",
                    "type": "synonym"
                },
                {
                    "name": "dickkopf-related protein 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "dickkopf-related protein 1",
                    "type": "synonym"
                },
                {
                    "name": "hDkk-1",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "DKK1",
                    "type": "recommended"
                },
                {
                    "name": "DKK-1",
                    "type": "synonym"
                },
                {
                    "name": "DKK1",
                    "type": "synonym"
                },
                {
                    "name": "PRO1008",
                    "type": "synonym"
                },
                {
                    "name": "SK",
                    "type": "synonym"
                }
            ],
            "record_id": "O94907-1",
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                {
                    "id": "0050851",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050851"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q99075-1",
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                {
                    "name": "Homo sapiens",
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                    "common_name": "Human",
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                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                {
                    "name": "Proheparin-binding EGF-like growth factor",
                    "type": "recommended"
                },
                {
                    "name": "DT-R",
                    "type": "synonym"
                },
                {
                    "name": "Diphtheria toxin receptor",
                    "type": "synonym"
                },
                {
                    "name": "diphtheria toxin receptor (heparin-binding EGF-like growth factor)",
                    "type": "synonym"
                },
                {
                    "name": "diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)",
                    "type": "synonym"
                },
                {
                    "name": "proheparin-binding EGF-like growth factor precursor",
                    "type": "synonym"
                },
                {
                    "name": "proheparin-binding EGF-like growth factor",
                    "type": "synonym"
                }
            ],
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                {
                    "name": "HBEGF",
                    "type": "recommended"
                },
                {
                    "name": "DTR",
                    "type": "synonym"
                },
                {
                    "name": "DTSF",
                    "type": "synonym"
                },
                {
                    "name": "DTS",
                    "type": "synonym"
                },
                {
                    "name": "HBEGF",
                    "type": "synonym"
                },
                {
                    "name": "HEGFL",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050851",
                    "database": "AGR",
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                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q13093-1",
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                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Platelet-activating factor acetylhydrolase",
                    "type": "recommended"
                },
                {
                    "name": "1-alkyl-2-acetylglycerophosphocholine esterase",
                    "type": "synonym"
                },
                {
                    "name": "2-acetyl-1-alkylglycerophosphocholine esterase",
                    "type": "synonym"
                },
                {
                    "name": "3.1.1.47",
                    "type": "synonym"
                },
                {
                    "name": "Group-VIIA phospholipase A2",
                    "type": "synonym"
                },
                {
                    "name": "LDL-PLA(2)",
                    "type": "synonym"
                },
                {
                    "name": "LDL-associated phospholipase A2",
                    "type": "synonym"
                },
                {
                    "name": "PAF 2-acylhydrolase",
                    "type": "synonym"
                },
                {
                    "name": "PAF acetylhydrolase",
                    "type": "synonym"
                },
                {
                    "name": "gVIIA-PLA2",
                    "type": "synonym"
                },
                {
                    "name": "group-VIIA phospholipase A2",
                    "type": "synonym"
                },
                {
                    "name": "lipoprotein-associated phospholipase A2",
                    "type": "synonym"
                },
                {
                    "name": "phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)",
                    "type": "synonym"
                },
                {
                    "name": "platelet-activating factor acetylhydrolase precursor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "PLA2G7",
                    "type": "recommended"
                },
                {
                    "name": "LDL-PLA2",
                    "type": "synonym"
                },
                {
                    "name": "LP-PLA2",
                    "type": "synonym"
                },
                {
                    "name": "PAFAD",
                    "type": "synonym"
                },
                {
                    "name": "PAFAH",
                    "type": "synonym"
                },
                {
                    "name": "PLA2G7",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050851",
                    "database": "AGR",
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                }
            ]
        },
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            "uniprot_canonical_ac": "P12821-1",
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                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
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                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Angiotensin-converting enzyme",
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                },
                {
                    "name": "3.4.15.1",
                    "type": "synonym"
                },
                {
                    "name": "ACE",
                    "type": "synonym"
                },
                {
                    "name": "CD143 antigen",
                    "type": "synonym"
                },
                {
                    "name": "Dipeptidyl carboxypeptidase I",
                    "type": "synonym"
                },
                {
                    "name": "Kininase II",
                    "type": "synonym"
                },
                {
                    "name": "angiotensin I converting enzyme (peptidyl-dipeptidase A) 1",
                    "type": "synonym"
                },
                {
                    "name": "angiotensin-converting enzyme isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "carboxycathepsin",
                    "type": "synonym"
                },
                {
                    "name": "dipeptidyl carboxypeptidase 1",
                    "type": "synonym"
                },
                {
                    "name": "dipeptidyl carboxypeptidase I",
                    "type": "synonym"
                },
                {
                    "name": "kininase II",
                    "type": "synonym"
                },
                {
                    "name": "peptidase P",
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                }
            ],
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                {
                    "name": "ACE",
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                {
                    "name": "ACE1",
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                },
                {
                    "name": "ACE",
                    "type": "synonym"
                },
                {
                    "name": "CD143",
                    "type": "synonym"
                },
                {
                    "name": "DCP1",
                    "type": "synonym"
                },
                {
                    "name": "DCP",
                    "type": "synonym"
                }
            ],
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                {
                    "id": "0050851",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050851"
                }
            ]
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                    "name": "Homo sapiens",
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                }
            ],
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                {
                    "name": "Pleckstrin homology domain-containing family A member 7",
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                    "name": "PH domain-containing family A member 7",
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                },
                {
                    "name": "pleckstrin homology domain containing, family A member 2",
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                },
                {
                    "name": "pleckstrin homology domain containing, family A member 7",
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                },
                {
                    "name": "pleckstrin homology domain-containing family A member 6",
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                {
                    "name": "pleckstrin homology domain-containing family A member 7 isoform 1",
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                {
                    "name": "PLEKHA7",
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                    "id": "0050851",
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            ]
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                    "name": "Homo sapiens",
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            ],
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                {
                    "name": "Type-2 angiotensin II receptor",
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                    "name": "AT2 receptor",
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                {
                    "name": "Angiotensin II type-2 receptor",
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                },
                {
                    "name": "angiotensin II type-2 receptor",
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                {
                    "name": "type-2 angiotensin II receptor isoform 1",
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                {
                    "name": "type-2 angiotensin II receptor",
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                    "name": "AGTR2",
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                    "name": "AGTR2",
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                    "name": "AT2",
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                    "name": "ATGR2",
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                    "name": "MRX88",
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            ],
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                    "id": "0050851",
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            ]
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                {
                    "name": "Homo sapiens",
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                }
            ],
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                {
                    "name": "SHC-transforming protein 1",
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                {
                    "name": "SH2 domain protein C1",
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                },
                {
                    "name": "SHC (Src homology 2 domain containing) transforming protein 1",
                    "type": "synonym"
                },
                {
                    "name": "SHC-transforming protein 1 isoform 3",
                    "type": "synonym"
                },
                {
                    "name": "SHC-transforming protein 3",
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                },
                {
                    "name": "SHC-transforming protein A",
                    "type": "synonym"
                },
                {
                    "name": "Src homology 2 domain-containing-transforming protein C1",
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                }
            ],
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                {
                    "name": "SHC1",
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                },
                {
                    "name": "SHC1",
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                },
                {
                    "name": "SHCA",
                    "type": "synonym"
                },
                {
                    "name": "SHC",
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            ],
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                    "id": "0050851",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050851"
                }
            ]
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                    "name": "Homo sapiens",
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                    "name": "Matrix metalloproteinase-9",
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                    "name": "3.4.24.35",
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                {
                    "name": "92 kDa gelatinase",
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                {
                    "name": "92 kDa type IV collagenase",
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                {
                    "name": "GELB",
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                {
                    "name": "Gelatinase B",
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                {
                    "name": "MMP-9",
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                },
                {
                    "name": "macrophage gelatinase",
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                {
                    "name": "matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)",
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                },
                {
                    "name": "matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)",
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                },
                {
                    "name": "matrix metalloproteinase-9 preproprotein",
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                {
                    "name": "type V collagenase",
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                }
            ],
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                    "name": "MMP9",
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                    "name": "GELB",
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                {
                    "name": "MANDP2",
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                {
                    "name": "MMP-9",
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                    "name": "MMP9",
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                    "id": "0050851",
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                    "name": "Plasminogen activator inhibitor 1",
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                    "name": "Endothelial plasminogen activator inhibitor",
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                    "name": "PAI-1",
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                {
                    "name": "PAI",
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                {
                    "name": "Serpin E1",
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                },
                {
                    "name": "endothelial plasminogen activator inhibitor",
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                {
                    "name": "plasminogen activator inhibitor 1 isoform 2 precursor",
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                {
                    "name": "serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1",
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                {
                    "name": "serpin E1",
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                {
                    "name": "serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1",
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                    "name": "PAI-1",
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                {
                    "name": "PAI1",
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                {
                    "name": "PAI",
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                    "name": "PLANH1",
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                    "name": "SERPINE1",
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                    "id": "0050851",
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                    "name": "Apo-E",
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                {
                    "name": "apolipoprotein E isoform b precursor",
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                {
                    "name": "apolipoprotein E3",
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                    "name": "AD2",
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                    "name": "APO-E",
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                {
                    "name": "APOE",
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                {
                    "name": "ApoE4",
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                {
                    "name": "LDLCQ5",
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                    "id": "0050851",
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                    "name": "Interstitial collagenase",
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                    "name": "3.4.24.7",
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                {
                    "name": "Fibroblast collagenase",
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                },
                {
                    "name": "MMP-1",
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                },
                {
                    "name": "Matrix metalloproteinase-1",
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                {
                    "name": "fibroblast collagenase",
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                },
                {
                    "name": "interstitial collagenase isoform 1 preproprotein",
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                {
                    "name": "matrix metallopeptidase 1 (interstitial collagenase)",
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                {
                    "name": "matrix metalloprotease 1",
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            ],
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                    "name": "CLG",
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                    "name": "MMP1",
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                    "id": "0050851",
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                    "url": "https://www.alliancegenome.org/disease/DOID:0050851"
                }
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        {
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                    "name": "Homo sapiens",
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                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
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                {
                    "name": "Peroxisome proliferator-activated receptor gamma",
                    "type": "recommended"
                },
                {
                    "name": "Nuclear receptor subfamily 1 group C member 3",
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                },
                {
                    "name": "PPAR-gamma",
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                },
                {
                    "name": "nuclear receptor subfamily 1 group C member 3",
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                },
                {
                    "name": "peroxisome proliferator-activated receptor gamma isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator-activated receptor-gamma 5",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator-activated receptor-gamma splicing",
                    "type": "synonym"
                }
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                    "name": "PPARG",
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                {
                    "name": "CIMT1",
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                },
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                    "name": "FPLD3",
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}