{
    "disease_id": "DOID:0050850",
    "recommended_name": {
        "id": "DOID:0050850",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0050850",
        "name": "diabetic encephalopathy",
        "description": "A brain disease that is characterized by functional impairment of cognition, cerebral signal conduction, neurotransmission and synaptic plasticity, and underlying structural pathology associated with diabetes."
    },
    "synonyms": [],
    "children": [],
    "id_list": [
        "DOID:0050850"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0050850",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050850",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8M1PEI8-1",
            "uniprot_ac": "A0A8M1PEI8",
            "uniprot_id": "A0A8M1PEI8_DANRE",
            "refseq_ac": "NP_998232",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Dual specificity protein phosphatase",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.16",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.48",
                    "type": "synonym"
                },
                {
                    "name": "dual specificity protein phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "mkp-1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "dusp1",
                    "type": "recommended"
                },
                {
                    "name": "cb269",
                    "type": "synonym"
                },
                {
                    "name": "dusp1",
                    "type": "synonym"
                },
                {
                    "name": "id:ibd2586",
                    "type": "synonym"
                },
                {
                    "name": "sb:cb269",
                    "type": "synonym"
                },
                {
                    "name": "wu:fd19g02",
                    "type": "synonym"
                },
                {
                    "name": "wu:fe50g09",
                    "type": "synonym"
                },
                {
                    "name": "zgc:55920",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M1PEI8-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8M3AVR7-1",
            "uniprot_ac": "A0A8M3AVR7",
            "uniprot_id": "A0A8M3AVR7_DANRE",
            "refseq_ac": "XP_009302769",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Glycogen synthase kinase-3 beta",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.26",
                    "type": "synonym"
                },
                {
                    "name": "glycogen synthase kinase-3 beta isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "gsk3ba",
                    "type": "recommended"
                },
                {
                    "name": "GSK-3[b]",
                    "type": "synonym"
                },
                {
                    "name": "GSK3",
                    "type": "synonym"
                },
                {
                    "name": "fb68h05",
                    "type": "synonym"
                },
                {
                    "name": "fk80d11",
                    "type": "synonym"
                },
                {
                    "name": "gsk3ba",
                    "type": "synonym"
                },
                {
                    "name": "gsk3b",
                    "type": "synonym"
                },
                {
                    "name": "wu:fb68h05",
                    "type": "synonym"
                },
                {
                    "name": "wu:fk80d11",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M3AVR7-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0R4IL71-1",
            "uniprot_ac": "A0A0R4IL71",
            "uniprot_id": "A0A0R4IL71_DANRE",
            "refseq_ac": "NP_001082994",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-degrading enzyme",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.56",
                    "type": "synonym"
                },
                {
                    "name": "Insulin protease",
                    "type": "synonym"
                },
                {
                    "name": "Insulysin",
                    "type": "synonym"
                },
                {
                    "name": "insulin-degrading enzyme isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "insulysin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ide",
                    "type": "recommended"
                },
                {
                    "name": "ide",
                    "type": "synonym"
                },
                {
                    "name": "zgc:162603",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0R4IL71-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P28563-1",
            "uniprot_ac": "P28563",
            "uniprot_id": "DUS1_MOUSE",
            "refseq_ac": "NP_038670",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Dual specificity protein phosphatase 1",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.16",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.48",
                    "type": "synonym"
                },
                {
                    "name": "MAP kinase phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "MKP-1",
                    "type": "synonym"
                },
                {
                    "name": "Mitogen-activated protein kinase phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "Protein-tyrosine phosphatase 3CH134",
                    "type": "synonym"
                },
                {
                    "name": "Protein-tyrosine phosphatase ERP",
                    "type": "synonym"
                },
                {
                    "name": "dual specificity protein phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase phosphatase-1",
                    "type": "synonym"
                },
                {
                    "name": "protein tyrosine phosphatase, non-receptor type 16",
                    "type": "synonym"
                },
                {
                    "name": "protein-tyrosine phosphatase 3CH134",
                    "type": "synonym"
                },
                {
                    "name": "protein-tyrosine phosphatase ERP",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Dusp1",
                    "type": "recommended"
                },
                {
                    "name": "3CH134",
                    "type": "synonym"
                },
                {
                    "name": "3ch134",
                    "type": "synonym"
                },
                {
                    "name": "Dusp1",
                    "type": "synonym"
                },
                {
                    "name": "MKP1",
                    "type": "synonym"
                },
                {
                    "name": "Mkp1",
                    "type": "synonym"
                },
                {
                    "name": "Ptpn10",
                    "type": "synonym"
                },
                {
                    "name": "Ptpn16",
                    "type": "synonym"
                },
                {
                    "name": "erp",
                    "type": "synonym"
                },
                {
                    "name": "mkp-1",
                    "type": "synonym"
                }
            ],
            "record_id": "P28563-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P12023-1",
            "uniprot_ac": "P12023",
            "uniprot_id": "A4_MOUSE",
            "refseq_ac": "NP_001185752",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Amyloid-beta precursor protein",
                    "type": "recommended"
                },
                {
                    "name": "ABPP",
                    "type": "synonym"
                },
                {
                    "name": "AG",
                    "type": "synonym"
                },
                {
                    "name": "AID(50)",
                    "type": "synonym"
                },
                {
                    "name": "AID(57)",
                    "type": "synonym"
                },
                {
                    "name": "AID(59)",
                    "type": "synonym"
                },
                {
                    "name": "APP-C57",
                    "type": "synonym"
                },
                {
                    "name": "APP-C59",
                    "type": "synonym"
                },
                {
                    "name": "APP-C99",
                    "type": "synonym"
                },
                {
                    "name": "APP",
                    "type": "synonym"
                },
                {
                    "name": "Alpha-CTF",
                    "type": "synonym"
                },
                {
                    "name": "Alpha-secretase C-terminal fragment",
                    "type": "synonym"
                },
                {
                    "name": "Alzheimer disease amyloid A4 protein homolog",
                    "type": "synonym"
                },
                {
                    "name": "Alzheimer disease amyloid protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid intracellular domain 50",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid intracellular domain 57",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid intracellular domain 59",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid-beta (A4) precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid-beta A4 protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloidogenic glycoprotein",
                    "type": "synonym"
                },
                {
                    "name": "Beta-APP40",
                    "type": "synonym"
                },
                {
                    "name": "Beta-APP42",
                    "type": "synonym"
                },
                {
                    "name": "Beta-CTF",
                    "type": "synonym"
                },
                {
                    "name": "Beta-secretase C-terminal fragment",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-CTF(50)",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-CTF(57)",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-CTF(59)",
                    "type": "synonym"
                },
                {
                    "name": "alzheimer disease amyloid A4 protein homolog",
                    "type": "synonym"
                },
                {
                    "name": "alzheimer disease amyloid protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid beta (A4) precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid beta A4 protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid-beta precursor protein isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "amyloidogenic glycoprotein",
                    "type": "synonym"
                },
                {
                    "name": "appican",
                    "type": "synonym"
                },
                {
                    "name": "beta-amyloid precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "protease nexin II",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "App",
                    "type": "recommended"
                },
                {
                    "name": "A4",
                    "type": "synonym"
                },
                {
                    "name": "AD1",
                    "type": "synonym"
                },
                {
                    "name": "Abeta",
                    "type": "synonym"
                },
                {
                    "name": "Abpp",
                    "type": "synonym"
                },
                {
                    "name": "Adap",
                    "type": "synonym"
                },
                {
                    "name": "Ag",
                    "type": "synonym"
                },
                {
                    "name": "App",
                    "type": "synonym"
                },
                {
                    "name": "Cvap",
                    "type": "synonym"
                },
                {
                    "name": "E030013M08Rik",
                    "type": "synonym"
                },
                {
                    "name": "betaApp",
                    "type": "synonym"
                }
            ],
            "record_id": "P12023-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P37238-1",
            "uniprot_ac": "P37238",
            "uniprot_id": "PPARG_MOUSE",
            "refseq_ac": "NP_001120802",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Peroxisome proliferator-activated receptor gamma",
                    "type": "recommended"
                },
                {
                    "name": "Nuclear receptor subfamily 1 group C member 3",
                    "type": "synonym"
                },
                {
                    "name": "PPAR-gamma",
                    "type": "synonym"
                },
                {
                    "name": "nuclear receptor subfamily 1 group C member 3",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator activated receptor gamma 2",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator activated receptor gamma 4",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator-activated receptor gamma isoform 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pparg",
                    "type": "recommended"
                },
                {
                    "name": "Nr1c3",
                    "type": "synonym"
                },
                {
                    "name": "PPAR-gamma2",
                    "type": "synonym"
                },
                {
                    "name": "PPAR-gamma",
                    "type": "synonym"
                },
                {
                    "name": "PPARG",
                    "type": "synonym"
                },
                {
                    "name": "PPARgamma2",
                    "type": "synonym"
                },
                {
                    "name": "PPARgamma",
                    "type": "synonym"
                },
                {
                    "name": "Pparg",
                    "type": "synonym"
                }
            ],
            "record_id": "P37238-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9WV60-1",
            "uniprot_ac": "Q9WV60",
            "uniprot_id": "GSK3B_MOUSE",
            "refseq_ac": "NP_062801",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Glycogen synthase kinase-3 beta",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "2.7.11.26",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3 beta",
                    "type": "synonym"
                },
                {
                    "name": "Serine/threonine-protein kinase GSK3B",
                    "type": "synonym"
                },
                {
                    "name": "glycogen synthase kinase-3 beta isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase GSK3B",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Gsk3b",
                    "type": "recommended"
                },
                {
                    "name": "7330414F15Rik",
                    "type": "synonym"
                },
                {
                    "name": "8430431H08Rik",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3beta",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3",
                    "type": "synonym"
                },
                {
                    "name": "GSK3",
                    "type": "synonym"
                },
                {
                    "name": "Gsk3b",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9WV60-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9Z0W1-1",
            "uniprot_ac": "Q9Z0W1",
            "uniprot_id": "TNR16_MOUSE",
            "refseq_ac": "NP_150086",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Tumor necrosis factor receptor superfamily member 16",
                    "type": "recommended"
                },
                {
                    "name": "Low affinity neurotrophin receptor p75NTR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor p75NGFR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor p75NGR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor",
                    "type": "synonym"
                },
                {
                    "name": "NGF receptor",
                    "type": "synonym"
                },
                {
                    "name": "low affinity neurotrophin receptor p75NTR",
                    "type": "synonym"
                },
                {
                    "name": "low-affinity nerve growth factor receptor p75NGFR",
                    "type": "synonym"
                },
                {
                    "name": "low-affinity nerve growth factor receptor p75NGR",
                    "type": "synonym"
                },
                {
                    "name": "low-affinity nerve growth factor receptor",
                    "type": "synonym"
                },
                {
                    "name": "p75 neurotrophin receptor",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor receptor superfamily member 16 precursor",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor receptor superfamily member 16",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ngfr",
                    "type": "recommended"
                },
                {
                    "name": "LNGFR",
                    "type": "synonym"
                },
                {
                    "name": "Ngfr",
                    "type": "synonym"
                },
                {
                    "name": "Tnfrsf16",
                    "type": "synonym"
                },
                {
                    "name": "p75NGFR",
                    "type": "synonym"
                },
                {
                    "name": "p75NTR",
                    "type": "synonym"
                },
                {
                    "name": "p75",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9Z0W1-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q62151-1",
            "uniprot_ac": "Q62151",
            "uniprot_id": "RAGE_MOUSE",
            "refseq_ac": "NP_001258351",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Advanced glycation end product-specific receptor",
                    "type": "recommended"
                },
                {
                    "name": "Receptor for advanced glycation end products",
                    "type": "synonym"
                },
                {
                    "name": "advanced glycation end-products receptor",
                    "type": "synonym"
                },
                {
                    "name": "advanced glycosylation end product-specific receptor isoform b precursor",
                    "type": "synonym"
                },
                {
                    "name": "receptor for advanced glycosylation end products",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ager",
                    "type": "recommended"
                },
                {
                    "name": "Ager",
                    "type": "synonym"
                },
                {
                    "name": "RAGE",
                    "type": "synonym"
                },
                {
                    "name": "Rage",
                    "type": "synonym"
                }
            ],
            "record_id": "Q62151-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9JHR7-1",
            "uniprot_ac": "Q9JHR7",
            "uniprot_id": "IDE_MOUSE",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-degrading enzyme",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.56",
                    "type": "synonym"
                },
                {
                    "name": "Insulin protease",
                    "type": "synonym"
                },
                {
                    "name": "Insulinase",
                    "type": "synonym"
                },
                {
                    "name": "Insulysin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ide",
                    "type": "recommended"
                }
            ],
            "record_id": "Q9JHR7-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P38615-1",
            "uniprot_ac": "P38615",
            "uniprot_id": "RIM11_YEAST",
            "refseq_ac": "NP_013859",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein kinase RIM11/MSD1",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "Regulator of IME2 protein 11",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine protein kinase RIM11",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "RIM11",
                    "type": "recommended"
                },
                {
                    "name": "GSK3",
                    "type": "synonym"
                },
                {
                    "name": "MDS1",
                    "type": "synonym"
                },
                {
                    "name": "RIM11",
                    "type": "synonym"
                },
                {
                    "name": "YM9375.08",
                    "type": "synonym"
                }
            ],
            "record_id": "P38615-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P50873-1",
            "uniprot_ac": "P50873",
            "uniprot_id": "MRK1_YEAST",
            "refseq_ac": "NP_010204",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein kinase MRK1",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "putative serine/threonine protein kinase MRK1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "MRK1",
                    "type": "recommended"
                },
                {
                    "name": "MRK1",
                    "type": "synonym"
                }
            ],
            "record_id": "P50873-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q06010-1",
            "uniprot_ac": "Q06010",
            "uniprot_id": "STE23_YEAST",
            "refseq_ac": "NP_013493",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "A-factor-processing enzyme",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.-",
                    "type": "synonym"
                },
                {
                    "name": "Insulin-degrading enzyme homolog",
                    "type": "synonym"
                },
                {
                    "name": "metalloendopeptidase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "STE23",
                    "type": "recommended"
                },
                {
                    "name": "L8084.12",
                    "type": "synonym"
                },
                {
                    "name": "STE23",
                    "type": "synonym"
                }
            ],
            "record_id": "Q06010-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q63495-1",
            "uniprot_ac": "Q63495",
            "uniprot_id": "RAGE_RAT",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Advanced glycation end product-specific receptor",
                    "type": "recommended"
                },
                {
                    "name": "Receptor for advanced glycation end products",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ager",
                    "type": "recommended"
                },
                {
                    "name": "Rage",
                    "type": "synonym"
                }
            ],
            "record_id": "Q63495-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P07174-1",
            "uniprot_ac": "P07174",
            "uniprot_id": "TNR16_RAT",
            "refseq_ac": "NP_036742",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Tumor necrosis factor receptor superfamily member 16",
                    "type": "recommended"
                },
                {
                    "name": "Gp80-LNGFR",
                    "type": "synonym"
                },
                {
                    "name": "Low affinity neurotrophin receptor p75NTR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor p75NGFR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor p75NGR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor",
                    "type": "synonym"
                },
                {
                    "name": "NGF receptor",
                    "type": "synonym"
                },
                {
                    "name": "gp80-LNGFR",
                    "type": "synonym"
                },
                {
                    "name": "low affinity nerve growth factor receptor",
                    "type": "synonym"
                },
                {
                    "name": "low affinity neurotrophin receptor p75NTR",
                    "type": "synonym"
                },
                {
                    "name": "low-affinity nerve growth factor receptor p75NGFR",
                    "type": "synonym"
                },
                {
                    "name": "low-affinity nerve growth factor receptor p75NGR",
                    "type": "synonym"
                },
                {
                    "name": "nerve growth factor receptor (TNFR superfamily, member 16)",
                    "type": "synonym"
                },
                {
                    "name": "nerve growth factor receptor, fast",
                    "type": "synonym"
                },
                {
                    "name": "p75 ICD",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor receptor superfamily member 16 precursor",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor receptor superfamily member 16",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ngfr",
                    "type": "recommended"
                },
                {
                    "name": "LNGFR",
                    "type": "synonym"
                },
                {
                    "name": "Ngfr",
                    "type": "synonym"
                },
                {
                    "name": "RNNGFRR",
                    "type": "synonym"
                },
                {
                    "name": "Tnfrsf16",
                    "type": "synonym"
                },
                {
                    "name": "p75NTR",
                    "type": "synonym"
                },
                {
                    "name": "p75",
                    "type": "synonym"
                }
            ],
            "record_id": "P07174-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P18266-1",
            "uniprot_ac": "P18266",
            "uniprot_id": "GSK3B_RAT",
            "refseq_ac": "NP_114469",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Glycogen synthase kinase-3 beta",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "2.7.11.26",
                    "type": "synonym"
                },
                {
                    "name": "FA",
                    "type": "synonym"
                },
                {
                    "name": "Factor A",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3 beta",
                    "type": "synonym"
                },
                {
                    "name": "Serine/threonine-protein kinase GSK3B",
                    "type": "synonym"
                },
                {
                    "name": "factor A",
                    "type": "synonym"
                },
                {
                    "name": "glycogen synthase kinase-3 beta",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase GSK3B",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Gsk3b",
                    "type": "recommended"
                },
                {
                    "name": "Gsk3b",
                    "type": "synonym"
                }
            ],
            "record_id": "P18266-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O88275-1",
            "uniprot_ac": "O88275",
            "uniprot_id": "PPARG_RAT",
            "refseq_ac": "NP_001138838",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Peroxisome proliferator-activated receptor gamma",
                    "type": "recommended"
                },
                {
                    "name": "Nuclear receptor subfamily 1 group C member 3",
                    "type": "synonym"
                },
                {
                    "name": "PPAR-gamma",
                    "type": "synonym"
                },
                {
                    "name": "nuclear receptor subfamily 1 group C member 3",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator activator receptor, gamma",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator-activated receptor gamma isoform 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pparg",
                    "type": "recommended"
                },
                {
                    "name": "Nr1c3",
                    "type": "synonym"
                },
                {
                    "name": "PPARgamma2",
                    "type": "synonym"
                },
                {
                    "name": "Pparg",
                    "type": "synonym"
                }
            ],
            "record_id": "O88275-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P08592-1",
            "uniprot_ac": "P08592",
            "uniprot_id": "A4_RAT",
            "refseq_ac": "NP_062161",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Amyloid-beta precursor protein",
                    "type": "recommended"
                },
                {
                    "name": "ABPP",
                    "type": "synonym"
                },
                {
                    "name": "AG",
                    "type": "synonym"
                },
                {
                    "name": "APP",
                    "type": "synonym"
                },
                {
                    "name": "Alpha-CTF",
                    "type": "synonym"
                },
                {
                    "name": "Alpha-secretase C-terminal fragment",
                    "type": "synonym"
                },
                {
                    "name": "Alzheimer disease amyloid A4 protein homolog",
                    "type": "synonym"
                },
                {
                    "name": "Alzheimer disease amyloid protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid-beta (A4) precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid-beta A4 protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloidogenic glycoprotein",
                    "type": "synonym"
                },
                {
                    "name": "Beta-APP40",
                    "type": "synonym"
                },
                {
                    "name": "Beta-APP42",
                    "type": "synonym"
                },
                {
                    "name": "Beta-CTF",
                    "type": "synonym"
                },
                {
                    "name": "Beta-secretase C-terminal fragment",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-CTF(50)",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-CTF(57)",
                    "type": "synonym"
                },
                {
                    "name": "Gamma-CTF(59)",
                    "type": "synonym"
                },
                {
                    "name": "alzheimer disease amyloid A4 protein homolog",
                    "type": "synonym"
                },
                {
                    "name": "alzheimer disease amyloid protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid beta (A4) precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid beta A4 protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid-beta precursor protein precursor",
                    "type": "synonym"
                },
                {
                    "name": "amyloidogenic glycoprotein",
                    "type": "synonym"
                },
                {
                    "name": "beta-amyloid precursor protein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "App",
                    "type": "recommended"
                },
                {
                    "name": "A4",
                    "type": "synonym"
                },
                {
                    "name": "AD1",
                    "type": "synonym"
                },
                {
                    "name": "Abeta",
                    "type": "synonym"
                },
                {
                    "name": "App",
                    "type": "synonym"
                }
            ],
            "record_id": "P08592-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q64623-1",
            "uniprot_ac": "Q64623",
            "uniprot_id": "DUS1_RAT",
            "refseq_ac": "NP_446221",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Dual specificity protein phosphatase 1",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.16",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.48",
                    "type": "synonym"
                },
                {
                    "name": "3CH134/CL100 PTPase",
                    "type": "synonym"
                },
                {
                    "name": "MAP kinase phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "MAP kinase phosphatase-1",
                    "type": "synonym"
                },
                {
                    "name": "MKP-1",
                    "type": "synonym"
                },
                {
                    "name": "Mitogen-activated protein kinase phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "Protein-tyrosine phosphatase CL100",
                    "type": "synonym"
                },
                {
                    "name": "Protein-tyrosine phosphatase non-receptor type 16",
                    "type": "synonym"
                },
                {
                    "name": "dual specificity protein phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein (MAP) kinase phosphatase-1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "oxidative stress-inducible protein tyrosine phosphatase",
                    "type": "synonym"
                },
                {
                    "name": "protein-tyrosine phosphatase CL100",
                    "type": "synonym"
                },
                {
                    "name": "protein-tyrosine phosphatase non-receptor type 16",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Dusp1",
                    "type": "recommended"
                },
                {
                    "name": "ENSRNOG00000069024",
                    "type": "recommended"
                },
                {
                    "name": "3CH134",
                    "type": "synonym"
                },
                {
                    "name": "CL100",
                    "type": "synonym"
                },
                {
                    "name": "Cl100",
                    "type": "synonym"
                },
                {
                    "name": "Dusp1",
                    "type": "synonym"
                },
                {
                    "name": "MKP-1",
                    "type": "synonym"
                },
                {
                    "name": "Mkp1",
                    "type": "synonym"
                },
                {
                    "name": "Ptpn16",
                    "type": "synonym"
                }
            ],
            "record_id": "Q64623-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P35559-1",
            "uniprot_ac": "P35559",
            "uniprot_id": "IDE_RAT",
            "refseq_ac": "NP_037291",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-degrading enzyme",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.56",
                    "type": "synonym"
                },
                {
                    "name": "Insulin protease",
                    "type": "synonym"
                },
                {
                    "name": "Insulinase",
                    "type": "synonym"
                },
                {
                    "name": "Insulysin",
                    "type": "synonym"
                },
                {
                    "name": "insulin protease",
                    "type": "synonym"
                },
                {
                    "name": "insulin-degrading enzyme",
                    "type": "synonym"
                },
                {
                    "name": "insulinase",
                    "type": "synonym"
                },
                {
                    "name": "insulysin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ide",
                    "type": "recommended"
                },
                {
                    "name": "INSDEGM",
                    "type": "synonym"
                },
                {
                    "name": "Ide",
                    "type": "synonym"
                }
            ],
            "record_id": "P35559-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P97592-1",
            "uniprot_ac": "P97592",
            "uniprot_id": "MCPT4_RAT",
            "refseq_ac": "NP_062194",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Mast cell protease 4",
                    "type": "recommended"
                },
                {
                    "name": "3.4.21.-",
                    "type": "synonym"
                },
                {
                    "name": "Mast cell protease IV",
                    "type": "synonym"
                },
                {
                    "name": "mast cell protease 4 precursor",
                    "type": "synonym"
                },
                {
                    "name": "mast cell protease IV",
                    "type": "synonym"
                },
                {
                    "name": "rMCP-4",
                    "type": "synonym"
                },
                {
                    "name": "rMCP-IV",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Mcpt4",
                    "type": "recommended"
                },
                {
                    "name": "Mcpt4",
                    "type": "synonym"
                }
            ],
            "record_id": "P97592-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P14599-1",
            "uniprot_ac": "P14599",
            "uniprot_id": "A4_DROME",
            "refseq_ac": "NP_476626",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Amyloid-beta-like protein",
                    "type": "recommended"
                },
                {
                    "name": "APP-like",
                    "type": "synonym"
                },
                {
                    "name": "Appl-PA",
                    "type": "synonym"
                },
                {
                    "name": "CG7727-PA",
                    "type": "synonym"
                },
                {
                    "name": "amyloid Precursor-Like protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid precursor protein like",
                    "type": "synonym"
                },
                {
                    "name": "amyloid precursor protein-like",
                    "type": "synonym"
                },
                {
                    "name": "beta amyloid protein precursor-like, isoform A",
                    "type": "synonym"
                },
                {
                    "name": "beta amyloid protein precursor-like",
                    "type": "synonym"
                },
                {
                    "name": "beta-amyloid-protein-precursor-like",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Appl",
                    "type": "recommended"
                },
                {
                    "name": "APP-like",
                    "type": "synonym"
                },
                {
                    "name": "APPL",
                    "type": "synonym"
                },
                {
                    "name": "APP",
                    "type": "synonym"
                },
                {
                    "name": "Abeta",
                    "type": "synonym"
                },
                {
                    "name": "Appl",
                    "type": "synonym"
                },
                {
                    "name": "BcDNA:GH04413",
                    "type": "synonym"
                },
                {
                    "name": "CG7727",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG7727",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG7727",
                    "type": "synonym"
                },
                {
                    "name": "EG:65F1.5",
                    "type": "synonym"
                },
                {
                    "name": "appl",
                    "type": "synonym"
                },
                {
                    "name": "dAPPL",
                    "type": "synonym"
                },
                {
                    "name": "dAPPl",
                    "type": "synonym"
                },
                {
                    "name": "dAbeta",
                    "type": "synonym"
                }
            ],
            "record_id": "P14599-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P83101-1",
            "uniprot_ac": "P83101",
            "uniprot_id": "GSK3H_DROME",
            "refseq_ac": "NP_733426",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Putative glycogen synthase kinase-3 homolog",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.26",
                    "type": "synonym"
                },
                {
                    "name": "CG31003-PA",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3",
                    "type": "synonym"
                },
                {
                    "name": "Protein gasket",
                    "type": "synonym"
                },
                {
                    "name": "gasket",
                    "type": "synonym"
                },
                {
                    "name": "gskt-PA",
                    "type": "synonym"
                },
                {
                    "name": "mojoless",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "gskt",
                    "type": "recommended"
                },
                {
                    "name": "BEST:GH16447",
                    "type": "synonym"
                },
                {
                    "name": "BcDNA:AT21229",
                    "type": "synonym"
                },
                {
                    "name": "CG11338",
                    "type": "synonym"
                },
                {
                    "name": "CG31003",
                    "type": "synonym"
                },
                {
                    "name": "CT4237",
                    "type": "synonym"
                },
                {
                    "name": "Dm Gskt",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG31003",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3b",
                    "type": "synonym"
                },
                {
                    "name": "GSK3b",
                    "type": "synonym"
                },
                {
                    "name": "Gsk3b",
                    "type": "synonym"
                },
                {
                    "name": "Gskt",
                    "type": "synonym"
                },
                {
                    "name": "NEST:bs22e06",
                    "type": "synonym"
                },
                {
                    "name": "NGSK",
                    "type": "synonym"
                },
                {
                    "name": "SINA",
                    "type": "synonym"
                },
                {
                    "name": "gskt",
                    "type": "synonym"
                },
                {
                    "name": "mjl",
                    "type": "synonym"
                }
            ],
            "record_id": "P83101-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P18431-2",
            "uniprot_ac": "P18431",
            "uniprot_id": "SGG_DROME",
            "refseq_ac": "NP_476714",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein kinase shaggy",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "CG2621-PA",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3 kinase",
                    "type": "synonym"
                },
                {
                    "name": "GSK3betagr",
                    "type": "synonym"
                },
                {
                    "name": "Protein zeste-white 3",
                    "type": "synonym"
                },
                {
                    "name": "Shaggy/Glycogen synthase kinase 3",
                    "type": "synonym"
                },
                {
                    "name": "Shaggy/Zeste-white-3/Glycogen synthase kinase 3beta",
                    "type": "synonym"
                },
                {
                    "name": "Zeste-white3",
                    "type": "synonym"
                },
                {
                    "name": "Zw3 kinase",
                    "type": "synonym"
                },
                {
                    "name": "glycogen synthase Kinase-3",
                    "type": "synonym"
                },
                {
                    "name": "glycogen synthase kinase 3Beta",
                    "type": "synonym"
                },
                {
                    "name": "glycogen synthase kinase 3",
                    "type": "synonym"
                },
                {
                    "name": "glycogen synthase kinase-3beta",
                    "type": "synonym"
                },
                {
                    "name": "saggy",
                    "type": "synonym"
                },
                {
                    "name": "sgg-PA",
                    "type": "synonym"
                },
                {
                    "name": "shaggy, isoform A",
                    "type": "synonym"
                },
                {
                    "name": "shaggy-zeste white 3",
                    "type": "synonym"
                },
                {
                    "name": "shaggy/zeste-white 3",
                    "type": "synonym"
                },
                {
                    "name": "zest-white 3",
                    "type": "synonym"
                },
                {
                    "name": "zeste white 3",
                    "type": "synonym"
                },
                {
                    "name": "zeste white-3",
                    "type": "synonym"
                },
                {
                    "name": "zeste white3",
                    "type": "synonym"
                },
                {
                    "name": "zeste-white 3",
                    "type": "synonym"
                },
                {
                    "name": "zestewhite-3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "sgg",
                    "type": "recommended"
                },
                {
                    "name": "CG2621",
                    "type": "synonym"
                },
                {
                    "name": "DMSGG3",
                    "type": "synonym"
                },
                {
                    "name": "DMZ3K25Z",
                    "type": "synonym"
                },
                {
                    "name": "Dm Zw3",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG2621",
                    "type": "synonym"
                },
                {
                    "name": "Dmsgg3",
                    "type": "synonym"
                },
                {
                    "name": "EG:155E2.3",
                    "type": "synonym"
                },
                {
                    "name": "EG:BACR7C10.8",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3B",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3beta",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3",
                    "type": "synonym"
                },
                {
                    "name": "GSK3-beta",
                    "type": "synonym"
                },
                {
                    "name": "GSK3A",
                    "type": "synonym"
                },
                {
                    "name": "GSK3Beta",
                    "type": "synonym"
                },
                {
                    "name": "GSK3beta/SGG",
                    "type": "synonym"
                },
                {
                    "name": "GSK3betagr",
                    "type": "synonym"
                },
                {
                    "name": "GSK3beta",
                    "type": "synonym"
                },
                {
                    "name": "GSK3",
                    "type": "synonym"
                },
                {
                    "name": "GSKbeta",
                    "type": "synonym"
                },
                {
                    "name": "GSK",
                    "type": "synonym"
                },
                {
                    "name": "Gsk-3beta",
                    "type": "synonym"
                },
                {
                    "name": "Gsk-3",
                    "type": "synonym"
                },
                {
                    "name": "Gsk3-beta",
                    "type": "synonym"
                },
                {
                    "name": "Gsk3beta",
                    "type": "synonym"
                },
                {
                    "name": "Gsk3",
                    "type": "synonym"
                },
                {
                    "name": "SGG/GSK3b",
                    "type": "synonym"
                },
                {
                    "name": "SGG",
                    "type": "synonym"
                },
                {
                    "name": "SHAGGY",
                    "type": "synonym"
                },
                {
                    "name": "Sgg/Zw3/GSK3",
                    "type": "synonym"
                },
                {
                    "name": "Sgg",
                    "type": "synonym"
                },
                {
                    "name": "Shaggy",
                    "type": "synonym"
                },
                {
                    "name": "ZW-3",
                    "type": "synonym"
                },
                {
                    "name": "ZW3",
                    "type": "synonym"
                },
                {
                    "name": "Zw-3",
                    "type": "synonym"
                },
                {
                    "name": "Zw3-sh",
                    "type": "synonym"
                },
                {
                    "name": "Zw3/GSK3",
                    "type": "synonym"
                },
                {
                    "name": "Zw3[sgg]",
                    "type": "synonym"
                },
                {
                    "name": "Zw3",
                    "type": "synonym"
                },
                {
                    "name": "anon-WO03040301.254",
                    "type": "synonym"
                },
                {
                    "name": "gsk3",
                    "type": "synonym"
                },
                {
                    "name": "l(1)3Ba",
                    "type": "synonym"
                },
                {
                    "name": "l(1)G0055",
                    "type": "synonym"
                },
                {
                    "name": "l(1)G0183",
                    "type": "synonym"
                },
                {
                    "name": "l(1)G0263",
                    "type": "synonym"
                },
                {
                    "name": "l(1)G0335",
                    "type": "synonym"
                },
                {
                    "name": "l(1)zw3",
                    "type": "synonym"
                },
                {
                    "name": "sgG4",
                    "type": "synonym"
                },
                {
                    "name": "sgg-1",
                    "type": "synonym"
                },
                {
                    "name": "sgg-zw3",
                    "type": "synonym"
                },
                {
                    "name": "sgg/GSK3",
                    "type": "synonym"
                },
                {
                    "name": "sgg/zw3",
                    "type": "synonym"
                },
                {
                    "name": "sgg10",
                    "type": "synonym"
                },
                {
                    "name": "sgg39",
                    "type": "synonym"
                },
                {
                    "name": "sgg46",
                    "type": "synonym"
                },
                {
                    "name": "sgg",
                    "type": "synonym"
                },
                {
                    "name": "zw-3",
                    "type": "synonym"
                },
                {
                    "name": "zw3(sgg)",
                    "type": "synonym"
                },
                {
                    "name": "zw3/GSK3beta",
                    "type": "synonym"
                },
                {
                    "name": "zw3/sgg",
                    "type": "synonym"
                },
                {
                    "name": "zw3[sgg]",
                    "type": "synonym"
                },
                {
                    "name": "zw3",
                    "type": "synonym"
                },
                {
                    "name": "zw[3]",
                    "type": "synonym"
                }
            ],
            "record_id": "P18431-2",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P22817-1",
            "uniprot_ac": "P22817",
            "uniprot_id": "IDE_DROME",
            "refseq_ac": "NP_524182",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-degrading enzyme",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.56",
                    "type": "synonym"
                },
                {
                    "name": "CG5517-PB",
                    "type": "synonym"
                },
                {
                    "name": "Ide-PB",
                    "type": "synonym"
                },
                {
                    "name": "Insulin protease",
                    "type": "synonym"
                },
                {
                    "name": "Insulinase",
                    "type": "synonym"
                },
                {
                    "name": "Insulysin",
                    "type": "synonym"
                },
                {
                    "name": "insulin degrading enzyme",
                    "type": "synonym"
                },
                {
                    "name": "insulin degrading metalloproteinase",
                    "type": "synonym"
                },
                {
                    "name": "insulin-degrading enzyme",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ide",
                    "type": "recommended"
                },
                {
                    "name": "CG5517",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG5517",
                    "type": "synonym"
                },
                {
                    "name": "IDE",
                    "type": "synonym"
                },
                {
                    "name": "Ide",
                    "type": "synonym"
                },
                {
                    "name": "dIDE",
                    "type": "synonym"
                },
                {
                    "name": "dIde",
                    "type": "synonym"
                },
                {
                    "name": "dide",
                    "type": "synonym"
                },
                {
                    "name": "dlde",
                    "type": "synonym"
                },
                {
                    "name": "ide",
                    "type": "synonym"
                }
            ],
            "record_id": "P22817-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P20800-1",
            "uniprot_ac": "P20800",
            "uniprot_id": "EDN2_HUMAN",
            "refseq_ac": "NP_001289198",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Endothelin-2",
                    "type": "recommended"
                },
                {
                    "name": "ET-2",
                    "type": "synonym"
                },
                {
                    "name": "PPET2",
                    "type": "synonym"
                },
                {
                    "name": "Preproendothelin-2",
                    "type": "synonym"
                },
                {
                    "name": "endothelin-2 isoform 2 preproprotein",
                    "type": "synonym"
                },
                {
                    "name": "preproendothelin 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "EDN2",
                    "type": "recommended"
                },
                {
                    "name": "EDN2",
                    "type": "synonym"
                },
                {
                    "name": "ET-2",
                    "type": "synonym"
                },
                {
                    "name": "ET2",
                    "type": "synonym"
                },
                {
                    "name": "PPET2",
                    "type": "synonym"
                }
            ],
            "record_id": "P20800-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P00374-1",
            "uniprot_ac": "P00374",
            "uniprot_id": "DYR_HUMAN",
            "refseq_ac": "NP_000782",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Dihydrofolate reductase",
                    "type": "recommended"
                },
                {
                    "name": "1.5.1.3",
                    "type": "synonym"
                },
                {
                    "name": "dihydrofolate reductase isoform 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "DHFR",
                    "type": "recommended"
                },
                {
                    "name": "DHFR1",
                    "type": "synonym"
                },
                {
                    "name": "DHFR",
                    "type": "synonym"
                },
                {
                    "name": "DYR",
                    "type": "synonym"
                }
            ],
            "record_id": "P00374-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P14735-1",
            "uniprot_ac": "P14735",
            "uniprot_id": "IDE_HUMAN",
            "refseq_ac": "NP_001159418",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-degrading enzyme",
                    "type": "recommended"
                },
                {
                    "name": "3.4.24.56",
                    "type": "synonym"
                },
                {
                    "name": "Abeta-degrading protease",
                    "type": "synonym"
                },
                {
                    "name": "Insulin protease",
                    "type": "synonym"
                },
                {
                    "name": "Insulinase",
                    "type": "synonym"
                },
                {
                    "name": "Insulysin",
                    "type": "synonym"
                },
                {
                    "name": "insulin protease",
                    "type": "synonym"
                },
                {
                    "name": "insulin-degrading enzyme isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "insulinase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "IDE",
                    "type": "recommended"
                },
                {
                    "name": "IDE",
                    "type": "synonym"
                },
                {
                    "name": "INSULYSIN",
                    "type": "synonym"
                }
            ],
            "record_id": "P14735-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P37231-1",
            "uniprot_ac": "P37231",
            "uniprot_id": "PPARG_HUMAN",
            "refseq_ac": "NP_056953",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Peroxisome proliferator-activated receptor gamma",
                    "type": "recommended"
                },
                {
                    "name": "Nuclear receptor subfamily 1 group C member 3",
                    "type": "synonym"
                },
                {
                    "name": "PPAR-gamma",
                    "type": "synonym"
                },
                {
                    "name": "nuclear receptor subfamily 1 group C member 3",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator-activated receptor gamma isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator-activated receptor-gamma 5",
                    "type": "synonym"
                },
                {
                    "name": "peroxisome proliferator-activated receptor-gamma splicing",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "PPARG",
                    "type": "recommended"
                },
                {
                    "name": "CIMT1",
                    "type": "synonym"
                },
                {
                    "name": "FPLD3",
                    "type": "synonym"
                },
                {
                    "name": "GLM1",
                    "type": "synonym"
                },
                {
                    "name": "NR1C3",
                    "type": "synonym"
                },
                {
                    "name": "PPARG1",
                    "type": "synonym"
                },
                {
                    "name": "PPARG2",
                    "type": "synonym"
                },
                {
                    "name": "PPARG5",
                    "type": "synonym"
                },
                {
                    "name": "PPARG",
                    "type": "synonym"
                },
                {
                    "name": "PPARgamma",
                    "type": "synonym"
                }
            ],
            "record_id": "P37231-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P05067-1",
            "uniprot_ac": "P05067",
            "uniprot_id": "A4_HUMAN",
            "refseq_ac": "NP_000475",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Amyloid-beta precursor protein",
                    "type": "recommended"
                },
                {
                    "name": "ABPP",
                    "type": "synonym"
                },
                {
                    "name": "AICD-50",
                    "type": "synonym"
                },
                {
                    "name": "AICD-57",
                    "type": "synonym"
                },
                {
                    "name": "AICD-59",
                    "type": "synonym"
                },
                {
                    "name": "AID(50)",
                    "type": "synonym"
                },
                {
                    "name": "AID(57)",
                    "type": "synonym"
                },
                {
                    "name": "AID(59)",
                    "type": "synonym"
                },
                {
                    "name": "APPI",
                    "type": "synonym"
                },
                {
                    "name": "APP",
                    "type": "synonym"
                },
                {
                    "name": "Alpha-CTF",
                    "type": "synonym"
                },
                {
                    "name": "Alpha-secretase C-terminal fragment",
                    "type": "synonym"
                },
                {
                    "name": "Alzheimer disease amyloid A4 protein homolog",
                    "type": "synonym"
                },
                {
                    "name": "Alzheimer disease amyloid protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid intracellular domain 50",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid intracellular domain 57",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid intracellular domain 59",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid-beta (A4) precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "Amyloid-beta A4 protein",
                    "type": "synonym"
                },
                {
                    "name": "Beta-APP40",
                    "type": "synonym"
                },
                {
                    "name": "Beta-APP42",
                    "type": "synonym"
                },
                {
                    "name": "Beta-CTF",
                    "type": "synonym"
                },
                {
                    "name": "Beta-secretase C-terminal fragment",
                    "type": "synonym"
                },
                {
                    "name": "CVAP",
                    "type": "synonym"
                },
                {
                    "name": "Cerebral vascular amyloid peptide",
                    "type": "synonym"
                },
                {
                    "name": "PN-II",
                    "type": "synonym"
                },
                {
                    "name": "PreA4",
                    "type": "synonym"
                },
                {
                    "name": "Protease nexin-II",
                    "type": "synonym"
                },
                {
                    "name": "alzheimer disease amyloid A4 protein homolog",
                    "type": "synonym"
                },
                {
                    "name": "alzheimer disease amyloid protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid beta (A4) precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid beta A4 protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "amyloid-beta precursor protein isoform a precursor",
                    "type": "synonym"
                },
                {
                    "name": "beta-amyloid peptide(1-40)",
                    "type": "synonym"
                },
                {
                    "name": "beta-amyloid peptide(1-42)",
                    "type": "synonym"
                },
                {
                    "name": "beta-amyloid peptide",
                    "type": "synonym"
                },
                {
                    "name": "beta-amyloid precursor protein",
                    "type": "synonym"
                },
                {
                    "name": "cerebral vascular amyloid peptide",
                    "type": "synonym"
                },
                {
                    "name": "peptidase nexin-II",
                    "type": "synonym"
                },
                {
                    "name": "protease nexin-II",
                    "type": "synonym"
                },
                {
                    "name": "testicular tissue protein Li 2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "APP",
                    "type": "recommended"
                },
                {
                    "name": "A4",
                    "type": "synonym"
                },
                {
                    "name": "AAA",
                    "type": "synonym"
                },
                {
                    "name": "ABETA",
                    "type": "synonym"
                },
                {
                    "name": "ABPP",
                    "type": "synonym"
                },
                {
                    "name": "AD1",
                    "type": "synonym"
                },
                {
                    "name": "APPI",
                    "type": "synonym"
                },
                {
                    "name": "APP",
                    "type": "synonym"
                },
                {
                    "name": "CTFgamma",
                    "type": "synonym"
                },
                {
                    "name": "CVAP",
                    "type": "synonym"
                },
                {
                    "name": "PN-II",
                    "type": "synonym"
                },
                {
                    "name": "PN2",
                    "type": "synonym"
                },
                {
                    "name": "alpha-sAPP",
                    "type": "synonym"
                },
                {
                    "name": "preA4",
                    "type": "synonym"
                }
            ],
            "record_id": "P05067-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P28562-1",
            "uniprot_ac": "P28562",
            "uniprot_id": "DUS1_HUMAN",
            "refseq_ac": "NP_004408",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Dual specificity protein phosphatase 1",
                    "type": "recommended"
                },
                {
                    "name": "3.1.3.16",
                    "type": "synonym"
                },
                {
                    "name": "3.1.3.48",
                    "type": "synonym"
                },
                {
                    "name": "CL 100",
                    "type": "synonym"
                },
                {
                    "name": "Dual specificity protein phosphatase hVH1",
                    "type": "synonym"
                },
                {
                    "name": "MAP kinase phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "MKP-1",
                    "type": "synonym"
                },
                {
                    "name": "Mitogen-activated protein kinase phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "Protein-tyrosine phosphatase CL100",
                    "type": "synonym"
                },
                {
                    "name": "dual specificity protein phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "dual specificity protein phosphatase hVH1",
                    "type": "synonym"
                },
                {
                    "name": "mitogen-activated protein kinase phosphatase 1",
                    "type": "synonym"
                },
                {
                    "name": "protein-tyrosine phosphatase CL100",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine specific protein phosphatase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "DUSP1",
                    "type": "recommended"
                },
                {
                    "name": "CL100",
                    "type": "synonym"
                },
                {
                    "name": "DUSP1",
                    "type": "synonym"
                },
                {
                    "name": "HVH1",
                    "type": "synonym"
                },
                {
                    "name": "MKP-1",
                    "type": "synonym"
                },
                {
                    "name": "MKP1",
                    "type": "synonym"
                },
                {
                    "name": "PTPN10",
                    "type": "synonym"
                },
                {
                    "name": "VH1",
                    "type": "synonym"
                }
            ],
            "record_id": "P28562-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P49841-1",
            "uniprot_ac": "P49841",
            "uniprot_id": "GSK3B_HUMAN",
            "refseq_ac": "NP_001139628",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Glycogen synthase kinase-3 beta",
                    "type": "recommended"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "2.7.11.26",
                    "type": "synonym"
                },
                {
                    "name": "GSK-3 beta",
                    "type": "synonym"
                },
                {
                    "name": "Serine/threonine-protein kinase GSK3B",
                    "type": "synonym"
                },
                {
                    "name": "glycogen synthase kinase-3 beta isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein kinase GSK3B",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "GSK3B",
                    "type": "recommended"
                },
                {
                    "name": "GSK3B",
                    "type": "synonym"
                }
            ],
            "record_id": "P49841-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P08138-1",
            "uniprot_ac": "P08138",
            "uniprot_id": "TNR16_HUMAN",
            "refseq_ac": "NP_002498",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Tumor necrosis factor receptor superfamily member 16",
                    "type": "recommended"
                },
                {
                    "name": "Gp80-LNGFR",
                    "type": "synonym"
                },
                {
                    "name": "Low affinity neurotrophin receptor p75NTR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor p75NGFR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor p75NGR",
                    "type": "synonym"
                },
                {
                    "name": "Low-affinity nerve growth factor receptor",
                    "type": "synonym"
                },
                {
                    "name": "NGF receptor",
                    "type": "synonym"
                },
                {
                    "name": "TNFR superfamily, member 16",
                    "type": "synonym"
                },
                {
                    "name": "low affinity neurotrophin receptor p75NTR",
                    "type": "synonym"
                },
                {
                    "name": "low-affinity nerve growth factor receptor p75NGFR",
                    "type": "synonym"
                },
                {
                    "name": "low-affinity nerve growth factor receptor p75NGR",
                    "type": "synonym"
                },
                {
                    "name": "low-affinity nerve growth factor receptor",
                    "type": "synonym"
                },
                {
                    "name": "p75 ICD",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor receptor superfamily member 16 precursor",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor receptor superfamily member 16",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "NGFR",
                    "type": "recommended"
                },
                {
                    "name": "CD271",
                    "type": "synonym"
                },
                {
                    "name": "Gp80-LNGFR",
                    "type": "synonym"
                },
                {
                    "name": "NGFR",
                    "type": "synonym"
                },
                {
                    "name": "TNFRSF16",
                    "type": "synonym"
                },
                {
                    "name": "p75(NTR)",
                    "type": "synonym"
                },
                {
                    "name": "p75NTR",
                    "type": "synonym"
                }
            ],
            "record_id": "P08138-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q15109-1",
            "uniprot_ac": "Q15109",
            "uniprot_id": "RAGE_HUMAN",
            "refseq_ac": "NP_001127",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Advanced glycation end product-specific receptor",
                    "type": "recommended"
                },
                {
                    "name": "Advanced glycosylation end product-specific receptor",
                    "type": "synonym"
                },
                {
                    "name": "Receptor for advanced glycation end products",
                    "type": "synonym"
                },
                {
                    "name": "Receptor for advanced glycosylation end products",
                    "type": "synonym"
                },
                {
                    "name": "advanced glycosylation end product-specific receptor isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "receptor for advanced glycation end-products",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "AGER",
                    "type": "recommended"
                },
                {
                    "name": "AGER",
                    "type": "synonym"
                },
                {
                    "name": "RAGE",
                    "type": "synonym"
                },
                {
                    "name": "SCARJ1",
                    "type": "synonym"
                },
                {
                    "name": "sRAGE",
                    "type": "synonym"
                }
            ],
            "record_id": "Q15109-1",
            "evidence": [
                {
                    "id": "0050850",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050850"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0050850"
}