{
    "disease_id": "DOID:0050211",
    "recommended_name": {
        "id": "DOID:0050211",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0050211",
        "name": "swine influenza",
        "description": "An influenza that results_in infection located_in respiratory tract of pigs and humans, has_material_basis_in Influenza C virus (Gammainfluenzavirus influenzae), or has_material_basis_in Influenza A virus (Alphainfluenzavirus influenzae) including subtypes (H1N1, H1N2, H3N1, H3N2, and H2N3), which are transmitted_by direct contact with infected pigs. The infection in humans has_symptom fever, has_symptom lethargy, has_symptom lack of appetite, has_symptom coughing, has_symptom runny nose, has_symptom sore throat, has_symptom nausea, has_symptom vomiting, and has_symptom diarrhea."
    },
    "synonyms": [],
    "children": [],
    "id_list": [
        "DOID:0050211"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0050211",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050211",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0A8M9Q5U7-1",
            "uniprot_ac": "A0A8M9Q5U7",
            "uniprot_id": "A0A8M9Q5U7_DANRE",
            "refseq_ac": "XP_021330656",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform",
                    "type": "recommended"
                },
                {
                    "name": "2.7.1.137",
                    "type": "synonym"
                },
                {
                    "name": "2.7.1.153",
                    "type": "synonym"
                },
                {
                    "name": "2.7.1.154",
                    "type": "synonym"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "Phosphoinositide-3-kinase catalytic gamma polypeptide",
                    "type": "synonym"
                },
                {
                    "name": "Serine/threonine protein kinase PIK3CG",
                    "type": "synonym"
                },
                {
                    "name": "p120-PI3K",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "pik3cg",
                    "type": "recommended"
                },
                {
                    "name": "pik3cg",
                    "type": "synonym"
                },
                {
                    "name": "wu:fb15d07",
                    "type": "synonym"
                },
                {
                    "name": "zgc:77033",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A8M9Q5U7-1",
            "evidence": [
                {
                    "id": "0050211",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050211"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9JHG7-1",
            "uniprot_ac": "Q9JHG7",
            "uniprot_id": "PK3CG_MOUSE",
            "refseq_ac": "NP_001139672",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform",
                    "type": "recommended"
                },
                {
                    "name": "2.7.1.137",
                    "type": "synonym"
                },
                {
                    "name": "2.7.1.153",
                    "type": "synonym"
                },
                {
                    "name": "2.7.1.154",
                    "type": "synonym"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "PI3-kinase subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "PI3K-gamma",
                    "type": "synonym"
                },
                {
                    "name": "PI3Kgamma",
                    "type": "synonym"
                },
                {
                    "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "Phosphoinositide-3-kinase catalytic gamma polypeptide",
                    "type": "synonym"
                },
                {
                    "name": "PtdIns-3-kinase subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "PtdIns-3-kinase subunit p110-gamma",
                    "type": "synonym"
                },
                {
                    "name": "Serine/threonine protein kinase PIK3CG",
                    "type": "synonym"
                },
                {
                    "name": "p110gamma",
                    "type": "synonym"
                },
                {
                    "name": "p120-PI3K",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform",
                    "type": "synonym"
                },
                {
                    "name": "phosphoinositide-3-kinase, catalytic, gamma polypeptide",
                    "type": "synonym"
                },
                {
                    "name": "ptdIns-3-kinase subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "ptdIns-3-kinase subunit p110-gamma",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine protein kinase PIK3CG",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pik3cg",
                    "type": "recommended"
                },
                {
                    "name": "5830428L06Rik",
                    "type": "synonym"
                },
                {
                    "name": "PI3Kgamma",
                    "type": "synonym"
                },
                {
                    "name": "Pi3kg1",
                    "type": "synonym"
                },
                {
                    "name": "Pik3cg",
                    "type": "synonym"
                },
                {
                    "name": "p110gamma",
                    "type": "synonym"
                },
                {
                    "name": "p120-PI3K",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9JHG7-1",
            "evidence": [
                {
                    "id": "0050211",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050211"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9WVE0-1",
            "uniprot_ac": "Q9WVE0",
            "uniprot_id": "AICDA_MOUSE",
            "refseq_ac": "NP_033775",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Single-stranded DNA cytosine deaminase",
                    "type": "recommended"
                },
                {
                    "name": "3.5.4.38",
                    "type": "synonym"
                },
                {
                    "name": "AID",
                    "type": "synonym"
                },
                {
                    "name": "Activation-induced cytidine deaminase",
                    "type": "synonym"
                },
                {
                    "name": "Cytidine aminohydrolase",
                    "type": "synonym"
                },
                {
                    "name": "activation induced deaminase",
                    "type": "synonym"
                },
                {
                    "name": "cytidine aminohydrolase",
                    "type": "synonym"
                },
                {
                    "name": "single-stranded DNA cytosine deaminase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Aicda",
                    "type": "recommended"
                },
                {
                    "name": "Aicda",
                    "type": "synonym"
                },
                {
                    "name": "Aid",
                    "type": "synonym"
                },
                {
                    "name": "Arp2",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9WVE0-1",
            "evidence": [
                {
                    "id": "0050211",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050211"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A8I6AKZ7-1",
            "uniprot_ac": "A0A8I6AKZ7",
            "uniprot_id": "A0A8I6AKZ7_RAT",
            "refseq_ac": "",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Pik3cg",
                    "type": "recommended"
                }
            ],
            "record_id": "A0A8I6AKZ7-1",
            "evidence": [
                {
                    "id": "0050211",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050211"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "G3V7Y8-1",
            "uniprot_ac": "G3V7Y8",
            "uniprot_id": "G3V7Y8_RAT",
            "refseq_ac": "NP_001094249",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Single-stranded DNA cytosine deaminase",
                    "type": "recommended"
                },
                {
                    "name": "3.5.4.38",
                    "type": "synonym"
                },
                {
                    "name": "Activation-induced cytidine deaminase",
                    "type": "synonym"
                },
                {
                    "name": "Cytidine aminohydrolase",
                    "type": "synonym"
                },
                {
                    "name": "single-stranded DNA cytosine deaminase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Aicda",
                    "type": "recommended"
                },
                {
                    "name": "Aicda",
                    "type": "synonym"
                },
                {
                    "name": "aicda",
                    "type": "synonym"
                },
                {
                    "name": "aid",
                    "type": "synonym"
                }
            ],
            "record_id": "G3V7Y8-1",
            "evidence": [
                {
                    "id": "0050211",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050211"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9GZX7-1",
            "uniprot_ac": "Q9GZX7",
            "uniprot_id": "AICDA_HUMAN",
            "refseq_ac": "NP_001317272",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Single-stranded DNA cytosine deaminase",
                    "type": "recommended"
                },
                {
                    "name": "3.5.4.38",
                    "type": "synonym"
                },
                {
                    "name": "AID",
                    "type": "synonym"
                },
                {
                    "name": "Activation-induced cytidine deaminase",
                    "type": "synonym"
                },
                {
                    "name": "Cytidine aminohydrolase",
                    "type": "synonym"
                },
                {
                    "name": "cytidine aminohydrolase",
                    "type": "synonym"
                },
                {
                    "name": "epididymis secretory protein Li 284",
                    "type": "synonym"
                },
                {
                    "name": "integrated into Burkitt's lymphoma cell line Ramos",
                    "type": "synonym"
                },
                {
                    "name": "single-stranded DNA cytosine deaminase isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "single-stranded DNA cytosine deaminase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "AICDA",
                    "type": "recommended"
                },
                {
                    "name": "AICDA",
                    "type": "synonym"
                },
                {
                    "name": "AID",
                    "type": "synonym"
                },
                {
                    "name": "ARP2",
                    "type": "synonym"
                },
                {
                    "name": "CDA2",
                    "type": "synonym"
                },
                {
                    "name": "HEL-S-284",
                    "type": "synonym"
                },
                {
                    "name": "HIGM2",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9GZX7-1",
            "evidence": [
                {
                    "id": "0050211",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050211"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P48736-1",
            "uniprot_ac": "P48736",
            "uniprot_id": "PK3CG_HUMAN",
            "refseq_ac": "NP_001269355",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform",
                    "type": "recommended"
                },
                {
                    "name": "1-phosphatidylinositol 3-kinase",
                    "type": "synonym"
                },
                {
                    "name": "2.7.1.137",
                    "type": "synonym"
                },
                {
                    "name": "2.7.1.153",
                    "type": "synonym"
                },
                {
                    "name": "2.7.1.154",
                    "type": "synonym"
                },
                {
                    "name": "2.7.11.1",
                    "type": "synonym"
                },
                {
                    "name": "PI3-kinase subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "PI3K-gamma",
                    "type": "synonym"
                },
                {
                    "name": "PI3Kgamma",
                    "type": "synonym"
                },
                {
                    "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "Phosphoinositide-3-kinase catalytic gamma polypeptide",
                    "type": "synonym"
                },
                {
                    "name": "PtdIns-3-kinase subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "PtdIns-3-kinase subunit p110-gamma",
                    "type": "synonym"
                },
                {
                    "name": "Serine/threonine protein kinase PIK3CG",
                    "type": "synonym"
                },
                {
                    "name": "p110gamma",
                    "type": "synonym"
                },
                {
                    "name": "p120-PI3K",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 3 kinase gamma, p110 gamma",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 3-kinase catalytic 110-kD gamma",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform",
                    "type": "synonym"
                },
                {
                    "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "phosphoinositide-3-kinase gamma catalytic subunit",
                    "type": "synonym"
                },
                {
                    "name": "ptdIns-3-kinase subunit gamma",
                    "type": "synonym"
                },
                {
                    "name": "ptdIns-3-kinase subunit p110-gamma",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine protein kinase PIK3CG",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "PIK3CG",
                    "type": "recommended"
                },
                {
                    "name": "IMD97",
                    "type": "synonym"
                },
                {
                    "name": "PI3CG",
                    "type": "synonym"
                },
                {
                    "name": "PI3Kgamma",
                    "type": "synonym"
                },
                {
                    "name": "PI3K",
                    "type": "synonym"
                },
                {
                    "name": "PIK3CG",
                    "type": "synonym"
                },
                {
                    "name": "PIK3",
                    "type": "synonym"
                },
                {
                    "name": "p110gamma",
                    "type": "synonym"
                },
                {
                    "name": "p120-PI3K",
                    "type": "synonym"
                }
            ],
            "record_id": "P48736-1",
            "evidence": [
                {
                    "id": "0050211",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050211"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0050211"
}