{
    "disease_id": "DOID:0050200",
    "recommended_name": {
        "id": "DOID:0050200",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0050200",
        "name": "Korean hemorrhagic fever",
        "description": "A hemorrhagic fever with renal syndrome that results_in infection located_in kidney, has_material_basis_in Hantaan virus, which is transmitted_by the eurasian field mouse, Apodemus agrarius, or has_material_basis_in Seoul virus, which is transmitted_by norwegian rat, Rattus norvegicus. The infection has_symptom headache, has_symptom back pain, has_symptom abdominal pain, has_symptom fever, has_symptom chills, has_symptom nausea, has_symptom blurred vision, has_symptom flushing of the face, has_symptom redness of the eyes, has_symptom rash, has_symptom low blood pressure, has_symptom acute shock, has_symptom vascular leakage, and has_symptom acute kidney failure, which can cause severe fluid overload."
    },
    "synonyms": [],
    "children": [],
    "id_list": [
        "DOID:0050200"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0050200",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0050200",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0AC58G9P9-1",
            "uniprot_ac": "A0AC58G9P9",
            "uniprot_id": "A0AC58G9P9_DANRE",
            "refseq_ac": "XP_073766467",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein P3 isoform X1",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P3 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "foxp3b",
                    "type": "recommended"
                },
                {
                    "name": "foxp3b",
                    "type": "synonym"
                }
            ],
            "record_id": "A0AC58G9P9-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0AB32TTK0-1",
            "uniprot_ac": "A0AB32TTK0",
            "uniprot_id": "A0AB32TTK0_DANRE",
            "refseq_ac": "XP_068079112",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein P3a isoform X1",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P3a isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "foxp3a",
                    "type": "recommended"
                },
                {
                    "name": "foxp3a",
                    "type": "synonym"
                },
                {
                    "name": "foxp3",
                    "type": "synonym"
                }
            ],
            "record_id": "A0AB32TTK0-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P01590-1",
            "uniprot_ac": "P01590",
            "uniprot_id": "IL2RA_MOUSE",
            "refseq_ac": "NP_032393",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Interleukin-2 receptor subunit alpha",
                    "type": "recommended"
                },
                {
                    "name": "IL-2 receptor subunit alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL-2-RA",
                    "type": "synonym"
                },
                {
                    "name": "IL-2R alpha chain",
                    "type": "synonym"
                },
                {
                    "name": "IL-2R subunit alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL2-RA",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-2 receptor subunit alpha precursor",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-2 receptor subunit alpha",
                    "type": "synonym"
                },
                {
                    "name": "p55 chain",
                    "type": "synonym"
                },
                {
                    "name": "p55",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Il2ra",
                    "type": "recommended"
                },
                {
                    "name": "CD25",
                    "type": "synonym"
                },
                {
                    "name": "Il2ra",
                    "type": "synonym"
                },
                {
                    "name": "Il2r",
                    "type": "synonym"
                },
                {
                    "name": "Ly-43",
                    "type": "synonym"
                }
            ],
            "record_id": "P01590-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q99JB6-1",
            "uniprot_ac": "Q99JB6",
            "uniprot_id": "FOXP3_MOUSE",
            "refseq_ac": "NP_001186276",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein P3",
                    "type": "recommended"
                },
                {
                    "name": "Scurfin",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P3",
                    "type": "synonym"
                },
                {
                    "name": "scurfy",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Foxp3",
                    "type": "recommended"
                },
                {
                    "name": "Foxp3",
                    "type": "synonym"
                },
                {
                    "name": "JM2",
                    "type": "synonym"
                },
                {
                    "name": "scurfin",
                    "type": "synonym"
                },
                {
                    "name": "sf",
                    "type": "synonym"
                }
            ],
            "record_id": "Q99JB6-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P26897-1",
            "uniprot_ac": "P26897",
            "uniprot_id": "IL2RA_RAT",
            "refseq_ac": "NP_037295",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Interleukin-2 receptor subunit alpha",
                    "type": "recommended"
                },
                {
                    "name": "IL-2 receptor alpha subunit",
                    "type": "synonym"
                },
                {
                    "name": "IL-2 receptor subunit alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL-2-RA",
                    "type": "synonym"
                },
                {
                    "name": "IL-2R subunit alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL2-RA",
                    "type": "synonym"
                },
                {
                    "name": "interleukin 2 receptor, alpha chain",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-2 receptor subunit alpha precursor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Il2ra",
                    "type": "recommended"
                },
                {
                    "name": "IL2RAC",
                    "type": "synonym"
                },
                {
                    "name": "Il2ra",
                    "type": "synonym"
                }
            ],
            "record_id": "P26897-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0B4K6N2-1",
            "uniprot_ac": "A0A0B4K6N2",
            "uniprot_id": "A0A0B4K6N2_DROME",
            "refseq_ac": "NP_001247011",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "CG43067-PC",
                    "type": "synonym"
                },
                {
                    "name": "Forkhead box P, isoform C",
                    "type": "synonym"
                },
                {
                    "name": "FoxP-PC",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box P, isoform C",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box P",
                    "type": "synonym"
                },
                {
                    "name": "forkhead domain 85E",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FoxP",
                    "type": "recommended"
                },
                {
                    "name": "CG16899",
                    "type": "synonym"
                },
                {
                    "name": "CG32937",
                    "type": "synonym"
                },
                {
                    "name": "CG43067",
                    "type": "synonym"
                },
                {
                    "name": "DmFoxP",
                    "type": "synonym"
                },
                {
                    "name": "Dmcg16899",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG43067",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG43067",
                    "type": "synonym"
                },
                {
                    "name": "FoxP",
                    "type": "synonym"
                },
                {
                    "name": "dFoxP",
                    "type": "synonym"
                },
                {
                    "name": "fd85E",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0B4K6N2-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9UNE0-1",
            "uniprot_ac": "Q9UNE0",
            "uniprot_id": "EDAR_HUMAN",
            "refseq_ac": "NP_071731",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Tumor necrosis factor receptor superfamily member EDAR",
                    "type": "recommended"
                },
                {
                    "name": "Anhidrotic ectodysplasin receptor 1",
                    "type": "synonym"
                },
                {
                    "name": "Downless homolog",
                    "type": "synonym"
                },
                {
                    "name": "EDA-A1 receptor",
                    "type": "synonym"
                },
                {
                    "name": "Ectodermal dysplasia receptor",
                    "type": "synonym"
                },
                {
                    "name": "Ectodysplasin-A receptor",
                    "type": "synonym"
                },
                {
                    "name": "anhidrotic ectodysplasin receptor 1",
                    "type": "synonym"
                },
                {
                    "name": "downless homolog",
                    "type": "synonym"
                },
                {
                    "name": "downless, mouse, homolog of",
                    "type": "synonym"
                },
                {
                    "name": "ectodermal dysplasia receptor",
                    "type": "synonym"
                },
                {
                    "name": "ectodysplasin 1, anhidrotic receptor",
                    "type": "synonym"
                },
                {
                    "name": "ectodysplasin A1 receptor",
                    "type": "synonym"
                },
                {
                    "name": "hypohidrotic ectodermal dysplasia",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor receptor superfamily member EDAR precursor",
                    "type": "synonym"
                },
                {
                    "name": "tumor necrosis factor receptor superfamily member EDAR",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "EDAR",
                    "type": "recommended"
                },
                {
                    "name": "DL",
                    "type": "synonym"
                },
                {
                    "name": "ECTD10A",
                    "type": "synonym"
                },
                {
                    "name": "ECTD10B",
                    "type": "synonym"
                },
                {
                    "name": "ED1R",
                    "type": "synonym"
                },
                {
                    "name": "ED3",
                    "type": "synonym"
                },
                {
                    "name": "ED5",
                    "type": "synonym"
                },
                {
                    "name": "EDA-A1R",
                    "type": "synonym"
                },
                {
                    "name": "EDA1R",
                    "type": "synonym"
                },
                {
                    "name": "EDA3",
                    "type": "synonym"
                },
                {
                    "name": "EDAR",
                    "type": "synonym"
                },
                {
                    "name": "HRM1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9UNE0-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P01589-1",
            "uniprot_ac": "P01589",
            "uniprot_id": "IL2RA_HUMAN",
            "refseq_ac": "NP_000408",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Interleukin-2 receptor subunit alpha",
                    "type": "recommended"
                },
                {
                    "name": "IL-2 receptor subunit alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL-2-RA",
                    "type": "synonym"
                },
                {
                    "name": "IL-2R subunit alpha",
                    "type": "synonym"
                },
                {
                    "name": "IL2-RA",
                    "type": "synonym"
                },
                {
                    "name": "TAC antigen",
                    "type": "synonym"
                },
                {
                    "name": "interleukin 2 receptor, alpha",
                    "type": "synonym"
                },
                {
                    "name": "interleukin-2 receptor subunit alpha isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "p55",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "IL2RA",
                    "type": "recommended"
                },
                {
                    "name": "CD25",
                    "type": "synonym"
                },
                {
                    "name": "IDDM10",
                    "type": "synonym"
                },
                {
                    "name": "IL2RA",
                    "type": "synonym"
                },
                {
                    "name": "IL2R",
                    "type": "synonym"
                },
                {
                    "name": "IMD41",
                    "type": "synonym"
                },
                {
                    "name": "TCGFR",
                    "type": "synonym"
                },
                {
                    "name": "p55",
                    "type": "synonym"
                }
            ],
            "record_id": "P01589-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9BZS1-1",
            "uniprot_ac": "Q9BZS1",
            "uniprot_id": "FOXP3_HUMAN",
            "refseq_ac": "NP_001107849",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein P3",
                    "type": "recommended"
                },
                {
                    "name": "FOXP3delta7",
                    "type": "synonym"
                },
                {
                    "name": "Scurfin",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P3 isoform b",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein P3",
                    "type": "synonym"
                },
                {
                    "name": "immune dysregulation, polyendocrinopathy, enteropathy, X-linked",
                    "type": "synonym"
                },
                {
                    "name": "immunodeficiency, polyendocrinopathy, enteropathy, X-linked",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FOXP3",
                    "type": "recommended"
                },
                {
                    "name": "AIID",
                    "type": "synonym"
                },
                {
                    "name": "DIETER",
                    "type": "synonym"
                },
                {
                    "name": "FOXP3",
                    "type": "synonym"
                },
                {
                    "name": "IPEX",
                    "type": "synonym"
                },
                {
                    "name": "JM2",
                    "type": "synonym"
                },
                {
                    "name": "PIDX",
                    "type": "synonym"
                },
                {
                    "name": "XPID",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9BZS1-1",
            "evidence": [
                {
                    "id": "0050200",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050200"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0050200"
}