{
    "disease_id": "DOID:0111921",
    "recommended_name": {
        "id": "DOID:0111921",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0111921",
        "name": "spermatogenic failure 36",
        "description": "A spermatogenic failure characterized by spermatozoa showing anomalies of the head, acrosome, and nucleus of the sperm resulting in reduced fertility that has_material_basis_in heterozygous mutation in the PPP2R3C gene on chromosome 14q13.2."
    },
    "synonyms": [
        {
            "id": "DOID:0111921",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111921",
            "name": "SPGF36",
            "description": ""
        },
        {
            "id": "MONDO:0032739",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032739",
            "name": "spermatogenic failure 36",
            "description": ""
        },
        {
            "id": "MONDO:0032739",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032739",
            "name": "SPGF36",
            "description": ""
        },
        {
            "id": "MIM:618420",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/618420",
            "name": "Spermatogenic failure 36",
            "description": "Spermatogenic failure 36"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0111921"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0111921",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111921",
            "categories": []
        },
        {
            "id": "MONDO:0032739",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0032739",
            "categories": []
        },
        {
            "id": "MIM:618420",
            "database": "MIM",
            "url": "https://www.omim.org/entry/618420",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q803V3-1",
            "uniprot_ac": "Q803V3",
            "uniprot_id": "P2R3C_DANRE",
            "refseq_ac": "NP_956425",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma",
                    "type": "recommended"
                },
                {
                    "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ppp2r3c",
                    "type": "recommended"
                },
                {
                    "name": "ppp2r3c",
                    "type": "synonym"
                },
                {
                    "name": "zgc:55473",
                    "type": "synonym"
                }
            ],
            "record_id": "Q803V3-1",
            "evidence": [
                {
                    "id": "0111921",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111921"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9JK24-1",
            "uniprot_ac": "Q9JK24",
            "uniprot_id": "P2R3C_MOUSE",
            "refseq_ac": "NP_067504",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma",
                    "type": "recommended"
                },
                {
                    "name": "Protein phosphatase subunit G5PR",
                    "type": "synonym"
                },
                {
                    "name": "phosphatase subunit gene g4-1",
                    "type": "synonym"
                },
                {
                    "name": "protein phosphatase subunit G5PR",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ppp2r3c",
                    "type": "recommended"
                },
                {
                    "name": "4930511A21Rik",
                    "type": "synonym"
                },
                {
                    "name": "5730412A08Rik",
                    "type": "synonym"
                },
                {
                    "name": "G4-1",
                    "type": "synonym"
                },
                {
                    "name": "G5pr",
                    "type": "synonym"
                },
                {
                    "name": "MNCb-1932",
                    "type": "synonym"
                },
                {
                    "name": "Ppp2r3c",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9JK24-1",
            "evidence": [
                {
                    "id": "0111921",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111921"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q969Q6-1",
            "uniprot_ac": "Q969Q6",
            "uniprot_id": "P2R3C_HUMAN",
            "refseq_ac": "NP_001292084",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma",
                    "type": "recommended"
                },
                {
                    "name": "Protein phosphatase subunit G5PR",
                    "type": "synonym"
                },
                {
                    "name": "Rhabdomyosarcoma antigen MU-RMS-40.6A/6C",
                    "type": "synonym"
                },
                {
                    "name": "protein phosphatase 2 (formerly 2A), regulatory subunit B''",
                    "type": "synonym"
                },
                {
                    "name": "protein phosphatase 2, regulatory subunit B'', gamma",
                    "type": "synonym"
                },
                {
                    "name": "protein phosphatase subunit G5PR",
                    "type": "synonym"
                },
                {
                    "name": "rhabdomyosarcoma antigen MU-RMS-40.6A",
                    "type": "synonym"
                },
                {
                    "name": "rhabdomyosarcoma antigen Mu-RMS-40.6C",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform 2",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "PPP2R3C",
                    "type": "recommended"
                },
                {
                    "name": "C14orf10",
                    "type": "synonym"
                },
                {
                    "name": "G4-1",
                    "type": "synonym"
                },
                {
                    "name": "G5PR",
                    "type": "synonym"
                },
                {
                    "name": "G5pr",
                    "type": "synonym"
                },
                {
                    "name": "GDRM",
                    "type": "synonym"
                },
                {
                    "name": "MEGD",
                    "type": "synonym"
                },
                {
                    "name": "PPP2R3C",
                    "type": "synonym"
                },
                {
                    "name": "SPGF36",
                    "type": "synonym"
                }
            ],
            "record_id": "Q969Q6-1",
            "evidence": [
                {
                    "id": "618420",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/618420"
                },
                {
                    "id": "0111921",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111921"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q6AXZ3-1",
            "uniprot_ac": "Q6AXZ3",
            "uniprot_id": "P2R3C_RAT",
            "refseq_ac": "NP_001014218",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma",
                    "type": "recommended"
                },
                {
                    "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like",
                    "type": "synonym"
                },
                {
                    "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ppp2r3c",
                    "type": "recommended"
                },
                {
                    "name": "Ppp2r3c",
                    "type": "synonym"
                },
                {
                    "name": "RGD1309207",
                    "type": "synonym"
                }
            ],
            "record_id": "Q6AXZ3-1",
            "evidence": [
                {
                    "id": "0111921",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111921"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0111921"
}