{
    "disease_id": "DOID:0111108",
    "recommended_name": {
        "id": "DOID:0111108",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0111108",
        "name": "maturity-onset diabetes of the young type 10",
        "description": "A maturity-onset diabetes of the young that has_material_basis_in heterozygous mutation in the INS gene on chromosome 11p15.5."
    },
    "synonyms": [
        {
            "id": "DOID:0111108",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111108",
            "name": "MODY10",
            "description": ""
        },
        {
            "id": "MONDO:0013240",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013240",
            "name": "maturity-onset diabetes of the young type 10",
            "description": "Any maturity-onset diabetes of the young in which the cause of the disease is a mutation in the INS gene."
        },
        {
            "id": "MONDO:0013240",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013240",
            "name": "INS maturity-onset diabetes of the young (disease)",
            "description": ""
        },
        {
            "id": "MONDO:0013240",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013240",
            "name": "MODY10",
            "description": ""
        },
        {
            "id": "MONDO:0013240",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013240",
            "name": "maturity-onset diabetes of the young (disease) caused by mutation in INS",
            "description": ""
        },
        {
            "id": "MONDO:0013240",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013240",
            "name": "maturity-onset diabetes of the young, type 10",
            "description": ""
        },
        {
            "id": "MIM:613370",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/613370",
            "name": "Maturity-onset diabetes of the young 10",
            "description": "Maturity-onset diabetes of the young 10"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0111108"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0111108",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0111108",
            "categories": []
        },
        {
            "id": "MONDO:0013240",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0013240",
            "categories": []
        },
        {
            "id": "MIM:613370",
            "database": "MIM",
            "url": "https://www.omim.org/entry/613370",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0AB32T7F9-1",
            "uniprot_ac": "A0AB32T7F9",
            "uniprot_id": "A0AB32T7F9_DANRE",
            "refseq_ac": "XP_068069331",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin",
                    "type": "recommended"
                },
                {
                    "name": "preproinsulin b isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "insb",
                    "type": "recommended"
                },
                {
                    "name": "insb",
                    "type": "synonym"
                }
            ],
            "record_id": "A0AB32T7F9-1",
            "evidence": [
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O73727-1",
            "uniprot_ac": "O73727",
            "uniprot_id": "INS_DANRE",
            "refseq_ac": "NP_571131",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin",
                    "type": "recommended"
                },
                {
                    "name": "insa",
                    "type": "synonym"
                },
                {
                    "name": "insulin preproprotein",
                    "type": "synonym"
                },
                {
                    "name": "insulin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ins",
                    "type": "recommended"
                },
                {
                    "name": "ins",
                    "type": "synonym"
                },
                {
                    "name": "zgc:109842",
                    "type": "synonym"
                }
            ],
            "record_id": "O73727-1",
            "evidence": [
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P01326-1",
            "uniprot_ac": "P01326",
            "uniprot_id": "INS2_MOUSE",
            "refseq_ac": "NP_001172012",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-2",
                    "type": "recommended"
                },
                {
                    "name": "insulin-2 preproprotein",
                    "type": "synonym"
                },
                {
                    "name": "insulin-2",
                    "type": "synonym"
                },
                {
                    "name": "proinsulin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ins2",
                    "type": "recommended"
                },
                {
                    "name": "Ins-2",
                    "type": "synonym"
                },
                {
                    "name": "Ins2",
                    "type": "synonym"
                },
                {
                    "name": "InsII",
                    "type": "synonym"
                },
                {
                    "name": "Mody4",
                    "type": "synonym"
                },
                {
                    "name": "Mody",
                    "type": "synonym"
                }
            ],
            "record_id": "P01326-1",
            "evidence": [
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P01325-1",
            "uniprot_ac": "P01325",
            "uniprot_id": "INS1_MOUSE",
            "refseq_ac": "NP_032412",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-1",
                    "type": "recommended"
                },
                {
                    "name": "insulin-1 preproprotein",
                    "type": "synonym"
                },
                {
                    "name": "insulin-1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ins1",
                    "type": "recommended"
                },
                {
                    "name": "Ins-1",
                    "type": "synonym"
                },
                {
                    "name": "Ins1",
                    "type": "synonym"
                },
                {
                    "name": "Ins2-rs1",
                    "type": "synonym"
                }
            ],
            "record_id": "P01325-1",
            "evidence": [
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P01308-1",
            "uniprot_ac": "P01308",
            "uniprot_id": "INS_HUMAN",
            "refseq_ac": "NP_000198",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin",
                    "type": "recommended"
                },
                {
                    "name": "insulin preproprotein",
                    "type": "synonym"
                },
                {
                    "name": "preproinsulin",
                    "type": "synonym"
                },
                {
                    "name": "proinsulin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "INS",
                    "type": "recommended"
                },
                {
                    "name": "IDDM1",
                    "type": "synonym"
                },
                {
                    "name": "IDDM2",
                    "type": "synonym"
                },
                {
                    "name": "IDDM",
                    "type": "synonym"
                },
                {
                    "name": "ILPR",
                    "type": "synonym"
                },
                {
                    "name": "INS",
                    "type": "synonym"
                },
                {
                    "name": "IRDN",
                    "type": "synonym"
                },
                {
                    "name": "MODY10",
                    "type": "synonym"
                },
                {
                    "name": "PNDM4",
                    "type": "synonym"
                }
            ],
            "record_id": "P01308-1",
            "evidence": [
                {
                    "id": "613370",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/613370"
                },
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P01323-1",
            "uniprot_ac": "P01323",
            "uniprot_id": "INS2_RAT",
            "refseq_ac": "NP_062003",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-2",
                    "type": "recommended"
                },
                {
                    "name": "C-peptide",
                    "type": "synonym"
                },
                {
                    "name": "insulin-2 preproprotein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ins2",
                    "type": "recommended"
                },
                {
                    "name": "CP-II",
                    "type": "synonym"
                },
                {
                    "name": "Ins-2",
                    "type": "synonym"
                },
                {
                    "name": "Ins2",
                    "type": "synonym"
                }
            ],
            "record_id": "P01323-1",
            "evidence": [
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P01322-1",
            "uniprot_ac": "P01322",
            "uniprot_id": "INS1_RAT",
            "refseq_ac": "NP_062002",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Insulin-1",
                    "type": "recommended"
                },
                {
                    "name": "insulin-1 preproprotein",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ins1",
                    "type": "recommended"
                },
                {
                    "name": "Ins-1",
                    "type": "synonym"
                },
                {
                    "name": "Ins1",
                    "type": "synonym"
                }
            ],
            "record_id": "P01322-1",
            "evidence": [
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O60479-1",
            "uniprot_ac": "O60479",
            "uniprot_id": "DLX3_HUMAN",
            "refseq_ac": "NP_005211",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Homeobox protein DLX-3",
                    "type": "recommended"
                },
                {
                    "name": "homeobox protein DLX-3",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "DLX3",
                    "type": "recommended"
                },
                {
                    "name": "AI4",
                    "type": "synonym"
                },
                {
                    "name": "DLX3",
                    "type": "synonym"
                },
                {
                    "name": "TDO",
                    "type": "synonym"
                }
            ],
            "record_id": "O60479-1",
            "evidence": [
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q07687-1",
            "uniprot_ac": "Q07687",
            "uniprot_id": "DLX2_HUMAN",
            "refseq_ac": "NP_004396",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Homeobox protein DLX-2",
                    "type": "recommended"
                },
                {
                    "name": "distal-less homeo box 2",
                    "type": "synonym"
                },
                {
                    "name": "homeobox protein DLX-2",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "DLX2",
                    "type": "recommended"
                },
                {
                    "name": "DLX2",
                    "type": "synonym"
                },
                {
                    "name": "TES-1",
                    "type": "synonym"
                },
                {
                    "name": "TES1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q07687-1",
            "evidence": [
                {
                    "id": "0111108",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111108"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0111108"
}