{
    "disease_id": "DOID:0110620",
    "recommended_name": {
        "id": "DOID:0110620",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0110620",
        "name": "primary ciliary dyskinesia 35",
        "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with absent outer dynein arms, immotile cilia, variable occurence of laterality defects and recurrent upper and lower respiratory infections and has_material_basis_in homozygous mutation in the TTC25 gene on chromosome 17q21."
    },
    "synonyms": [
        {
            "id": "DOID:0110620",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110620",
            "name": "primary ciliary dyskinesia 35 with or without situs inversus",
            "description": ""
        },
        {
            "id": "DOID:0110620",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110620",
            "name": "CILD35",
            "description": ""
        },
        {
            "id": "MONDO:0014910",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014910",
            "name": "primary ciliary dyskinesia 35",
            "description": "Any primary ciliary dyskinesia in which the cause of the disease is a mutation in the TTC25 gene."
        },
        {
            "id": "MONDO:0014910",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014910",
            "name": "CILD35",
            "description": ""
        },
        {
            "id": "MONDO:0014910",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014910",
            "name": "TTC25 primary ciliary dyskinesia",
            "description": ""
        },
        {
            "id": "MONDO:0014910",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014910",
            "name": "ciliary dyskinesia, primary, 35",
            "description": ""
        },
        {
            "id": "MONDO:0014910",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014910",
            "name": "ciliary dyskinesia, primary, type 35",
            "description": ""
        },
        {
            "id": "MONDO:0014910",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014910",
            "name": "primary ciliary dyskinesia caused by mutation in TTC25",
            "description": ""
        },
        {
            "id": "MONDO:0014910",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014910",
            "name": "primary ciliary dyskinesia type 35",
            "description": ""
        },
        {
            "id": "MIM:617092",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/617092",
            "name": "Ciliary dyskinesia, primary, 35",
            "description": "Ciliary dyskinesia, primary, 35"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0110620"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0110620",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110620",
            "categories": []
        },
        {
            "id": "MONDO:0014910",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0014910",
            "categories": []
        },
        {
            "id": "MIM:617092",
            "database": "MIM",
            "url": "https://www.omim.org/entry/617092",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q7ZU45-1",
            "uniprot_ac": "Q7ZU45",
            "uniprot_id": "ODAD4_DANRE",
            "refseq_ac": "NP_956610",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Outer dynein arm-docking complex subunit 4",
                    "type": "recommended"
                },
                {
                    "name": "TPR repeat protein 25",
                    "type": "synonym"
                },
                {
                    "name": "Tetratricopeptide repeat protein 25",
                    "type": "synonym"
                },
                {
                    "name": "outer dynein arm-docking complex subunit 4",
                    "type": "synonym"
                },
                {
                    "name": "tetratricopeptide repeat domain 25",
                    "type": "synonym"
                },
                {
                    "name": "tetratricopeptide repeat protein 25",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "odad4",
                    "type": "recommended"
                },
                {
                    "name": "odad4",
                    "type": "synonym"
                },
                {
                    "name": "ttc25",
                    "type": "synonym"
                },
                {
                    "name": "zgc:56362",
                    "type": "synonym"
                }
            ],
            "record_id": "Q7ZU45-1",
            "evidence": [
                {
                    "id": "0110620",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110620"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9D4B2-1",
            "uniprot_ac": "Q9D4B2",
            "uniprot_id": "ODAD4_MOUSE",
            "refseq_ac": "NP_083194",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Outer dynein arm-docking complex subunit 4",
                    "type": "recommended"
                },
                {
                    "name": "TPR repeat protein 25",
                    "type": "synonym"
                },
                {
                    "name": "Tetratricopeptide repeat protein 25",
                    "type": "synonym"
                },
                {
                    "name": "outer dynein arm-docking complex subunit 4 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "outer dynein arm-docking complex subunit 4",
                    "type": "synonym"
                },
                {
                    "name": "tetratricopeptide repeat domain 25",
                    "type": "synonym"
                },
                {
                    "name": "tetratricopeptide repeat protein 25",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Odad4",
                    "type": "recommended"
                },
                {
                    "name": "4933404O19Rik",
                    "type": "synonym"
                },
                {
                    "name": "Odad4",
                    "type": "synonym"
                },
                {
                    "name": "Ttc25",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9D4B2-1",
            "evidence": [
                {
                    "id": "0110620",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110620"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q96NG3-1",
            "uniprot_ac": "Q96NG3",
            "uniprot_id": "ODAD4_HUMAN",
            "refseq_ac": "NP_113609",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Outer dynein arm-docking complex subunit 4",
                    "type": "recommended"
                },
                {
                    "name": "TPR repeat protein 25",
                    "type": "synonym"
                },
                {
                    "name": "Tetratricopeptide repeat protein 25",
                    "type": "synonym"
                },
                {
                    "name": "outer dynein arm-docking complex subunit 4 isoform 1",
                    "type": "synonym"
                },
                {
                    "name": "tetratricopeptide repeat domain 25",
                    "type": "synonym"
                },
                {
                    "name": "tetratricopeptide repeat protein 25",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "ODAD4",
                    "type": "recommended"
                },
                {
                    "name": "ODAD4",
                    "type": "synonym"
                },
                {
                    "name": "TTC25",
                    "type": "synonym"
                }
            ],
            "record_id": "Q96NG3-1",
            "evidence": [
                {
                    "id": "617092",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/617092"
                },
                {
                    "id": "0110620",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110620"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A0A0G2KAE9-1",
            "uniprot_ac": "A0A0G2KAE9",
            "uniprot_id": "A0A0G2KAE9_RAT",
            "refseq_ac": "NP_001100519",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Outer dynein arm-docking complex subunit 4",
                    "type": "recommended"
                },
                {
                    "name": "Tetratricopeptide repeat protein 25",
                    "type": "synonym"
                },
                {
                    "name": "outer dynein arm-docking complex subunit 4",
                    "type": "synonym"
                },
                {
                    "name": "tetratricopeptide repeat domain 25",
                    "type": "synonym"
                },
                {
                    "name": "tetratricopeptide repeat protein 25",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Odad4",
                    "type": "recommended"
                },
                {
                    "name": "Odad4",
                    "type": "synonym"
                },
                {
                    "name": "RGD1311859",
                    "type": "synonym"
                },
                {
                    "name": "Ttc25",
                    "type": "synonym"
                }
            ],
            "record_id": "A0A0G2KAE9-1",
            "evidence": [
                {
                    "id": "0110620",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110620"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9W295-1",
            "uniprot_ac": "Q9W295",
            "uniprot_id": "Q9W295_DROME",
            "refseq_ac": "NP_611637",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Outer dynein arm-docking complex subunit 4",
                    "type": "recommended"
                },
                {
                    "name": "CG13502-PA",
                    "type": "synonym"
                },
                {
                    "name": "Tetratricopeptide repeat protein 25",
                    "type": "synonym"
                },
                {
                    "name": "uncharacterized protein, isoform A",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Dmel\\CG13502",
                    "type": "recommended"
                },
                {
                    "name": "CG13502",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG13502",
                    "type": "synonym"
                },
                {
                    "name": "Dmel_CG13502",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9W295-1",
            "evidence": [
                {
                    "id": "0110620",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110620"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0110620"
}