{
    "disease_id": "DOID:0080079",
    "recommended_name": {
        "id": "DOID:0080079",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0080079",
        "name": "nonsyndromic congenital nail disorder 1",
        "description": "A nonsyndromic congenital nail disorder that is characterized by excessive longitudinal striations and numerous superficial pits on the nails, which have a distinctive rough, sand paper-like appearance."
    },
    "synonyms": [
        {
            "id": "DOID:0080079",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080079",
            "name": "twenty-nail dystrophy",
            "description": ""
        },
        {
            "id": "DOID:0080079",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080079",
            "name": "nonsyndromic congenital nail disorder 10",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "nonsyndromic congenital nail disorder 1",
            "description": "Nail dysplasia is an idiopathic nail dystrophy, beginning in early childhood, and characterized by excessive longitudinal striations and loss of nail luster affecting all 20 nails."
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "FZD6 inherited isolated nail anomaly",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "inherited isolated nail anomaly caused by mutation in FZD6",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "nail disorder, nonsyndromic congenital, type 10",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "nonsyndromic congenital nail disorder 10",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "nonsyndromic congenital nail disorder type 1",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "nonsyndromic congenital nail disorder type 10",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "onychodystrophy totalis",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "twenty-nail dystrophy",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "NDNC1",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "NDNC10",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "nail disorder, nonsyndromic congenital 1",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "nail disorder, nonsyndromic congenital, 1",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "nail disorder, nonsyndromic congenital, 10",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "sandpaper nails",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "trachyonychia",
            "description": ""
        },
        {
            "id": "MONDO:0008060",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "name": "twenty nail dystrophy",
            "description": ""
        },
        {
            "id": "MIM:161050",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/161050",
            "name": "Nail disorder, non-syndromic congenital, 1",
            "description": "Nail disorder, non-syndromic congenital, 1"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0080079"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0080079",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0080079",
            "categories": []
        },
        {
            "id": "MONDO:0008060",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0008060",
            "categories": []
        },
        {
            "id": "MIM:161050",
            "database": "MIM",
            "url": "https://www.omim.org/entry/161050",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q61089-1",
            "uniprot_ac": "Q61089",
            "uniprot_id": "FZD6_MOUSE",
            "refseq_ac": "NP_001155966",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Frizzled-6",
                    "type": "recommended"
                },
                {
                    "name": "Fz-6",
                    "type": "synonym"
                },
                {
                    "name": "frizzled homolog 6",
                    "type": "synonym"
                },
                {
                    "name": "frizzled-6 isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "frizzled-6",
                    "type": "synonym"
                },
                {
                    "name": "fz-6",
                    "type": "synonym"
                },
                {
                    "name": "mFz6",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Fzd6",
                    "type": "recommended"
                },
                {
                    "name": "Fz6",
                    "type": "synonym"
                },
                {
                    "name": "Fzd6",
                    "type": "synonym"
                },
                {
                    "name": "rst",
                    "type": "synonym"
                }
            ],
            "record_id": "Q61089-1",
            "evidence": [
                {
                    "id": "0080079",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080079"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O60353-1",
            "uniprot_ac": "O60353",
            "uniprot_id": "FZD6_HUMAN",
            "refseq_ac": "NP_001158087",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Frizzled-6",
                    "type": "recommended"
                },
                {
                    "name": "Fz-6",
                    "type": "synonym"
                },
                {
                    "name": "frizzled 6, seven transmembrane spanning receptor",
                    "type": "synonym"
                },
                {
                    "name": "frizzled family receptor 6",
                    "type": "synonym"
                },
                {
                    "name": "frizzled homolog 6",
                    "type": "synonym"
                },
                {
                    "name": "frizzled-6 isoform a precursor",
                    "type": "synonym"
                },
                {
                    "name": "hFz6",
                    "type": "synonym"
                },
                {
                    "name": "seven transmembrane helix receptor",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FZD6",
                    "type": "recommended"
                },
                {
                    "name": "FZ-6",
                    "type": "synonym"
                },
                {
                    "name": "FZ6",
                    "type": "synonym"
                },
                {
                    "name": "FZD6",
                    "type": "synonym"
                },
                {
                    "name": "HFZ6",
                    "type": "synonym"
                },
                {
                    "name": "NDNC10",
                    "type": "synonym"
                },
                {
                    "name": "NDNC1",
                    "type": "synonym"
                }
            ],
            "record_id": "O60353-1",
            "evidence": [
                {
                    "id": "161050",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/161050"
                },
                {
                    "id": "0080079",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080079"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "G3V6L1-1",
            "uniprot_ac": "G3V6L1",
            "uniprot_id": "G3V6L1_RAT",
            "refseq_ac": "NP_001124008",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Frizzled-6",
                    "type": "recommended"
                },
                {
                    "name": "frizzled family receptor 6",
                    "type": "synonym"
                },
                {
                    "name": "frizzled-6 precursor",
                    "type": "synonym"
                },
                {
                    "name": "frizzled-6",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Fzd6",
                    "type": "recommended"
                },
                {
                    "name": "Fzd6",
                    "type": "synonym"
                }
            ],
            "record_id": "G3V6L1-1",
            "evidence": [
                {
                    "id": "0080079",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080079"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0080079"
}