{
    "disease_id": "DOID:0070596",
    "recommended_name": {
        "id": "DOID:0070596",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0070596",
        "name": "X-linked spermatogenic failure 5",
        "description": "A spermatogenic failure characterized by asthenoteratozoospermia with multiple morphologic abnormalities of the sperm flagella that has_material_basis_in hemizygous mutation in the SSX1 gene on chromosome Xp11.23."
    },
    "synonyms": [
        {
            "id": "DOID:0070596",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070596",
            "name": "SPGFX5",
            "description": ""
        },
        {
            "id": "MONDO:0859477",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0859477",
            "name": "spermatogenic failure, X-linked, 5",
            "description": ""
        },
        {
            "id": "MIM:301099",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/301099",
            "name": "Spermatogenic failure, X-linked, 5",
            "description": "Spermatogenic failure, X-linked, 5"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0070596"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0070596",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070596",
            "categories": []
        },
        {
            "id": "MONDO:0859477",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0859477",
            "categories": []
        },
        {
            "id": "MIM:301099",
            "database": "MIM",
            "url": "https://www.omim.org/entry/301099",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A2AHC8-1",
            "uniprot_ac": "A2AHC8",
            "uniprot_id": "A2AHC8_MOUSE",
            "refseq_ac": "NP_001423289",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "SSX member B16",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member B family member",
                    "type": "synonym"
                },
                {
                    "name": "uncharacterized protein LOC436188",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ssxb16",
                    "type": "recommended"
                },
                {
                    "name": "EG436188",
                    "type": "synonym"
                },
                {
                    "name": "Gm5751",
                    "type": "synonym"
                },
                {
                    "name": "Ssxb16",
                    "type": "synonym"
                }
            ],
            "record_id": "A2AHC8-1",
            "evidence": [
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "B1AY40-1",
            "uniprot_ac": "B1AY40",
            "uniprot_id": "B1AY40_MOUSE",
            "refseq_ac": "NP_001075034",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "SSX member B8",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member B family member",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member B, breakpoint 8",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member B8",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ssxb8",
                    "type": "recommended"
                },
                {
                    "name": "Gm6592",
                    "type": "synonym"
                },
                {
                    "name": "Ssxb8",
                    "type": "synonym"
                }
            ],
            "record_id": "B1AY40-1",
            "evidence": [
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A2AHC7-1",
            "uniprot_ac": "A2AHC7",
            "uniprot_id": "A2AHC7_MOUSE",
            "refseq_ac": "NP_001075033",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "SSX member B14",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member B family member",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ssxb14",
                    "type": "recommended"
                },
                {
                    "name": "EG625480",
                    "type": "synonym"
                },
                {
                    "name": "Gm6592",
                    "type": "synonym"
                },
                {
                    "name": "Ssxb14",
                    "type": "synonym"
                }
            ],
            "record_id": "A2AHC7-1",
            "evidence": [
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "B1AUS7-1",
            "uniprot_ac": "B1AUS7",
            "uniprot_id": "SSXA1_MOUSE",
            "refseq_ac": "NP_001192015",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein SSXA1",
                    "type": "recommended"
                },
                {
                    "name": "Synovial sarcoma, X member A1",
                    "type": "synonym"
                },
                {
                    "name": "protein SSXA1",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member A, breakpoint 1",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member A1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ssxa1",
                    "type": "recommended"
                },
                {
                    "name": "Gm1532",
                    "type": "synonym"
                },
                {
                    "name": "Ssxa1",
                    "type": "synonym"
                },
                {
                    "name": "Ssxa",
                    "type": "synonym"
                }
            ],
            "record_id": "B1AUS7-1",
            "evidence": [
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A2BI73-1",
            "uniprot_ac": "A2BI73",
            "uniprot_id": "A2BI73_MOUSE",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "SSX member B15",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ssxb15",
                    "type": "recommended"
                },
                {
                    "name": "Gm14459",
                    "type": "synonym"
                }
            ],
            "record_id": "A2BI73-1",
            "evidence": [
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "A2BI74-1",
            "uniprot_ac": "A2BI74",
            "uniprot_id": "A2BI74_MOUSE",
            "refseq_ac": "NP_001192037",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "SSX member B6",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member B, breakpoint 6",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X member B6",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ssxb6",
                    "type": "recommended"
                },
                {
                    "name": "Ssxb6",
                    "type": "synonym"
                }
            ],
            "record_id": "A2BI74-1",
            "evidence": [
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q16384-1",
            "uniprot_ac": "Q16384",
            "uniprot_id": "SSX1_HUMAN",
            "refseq_ac": "NP_001265620",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Protein SSX1",
                    "type": "recommended"
                },
                {
                    "name": "CT5.1",
                    "type": "synonym"
                },
                {
                    "name": "Cancer/testis antigen 5.1",
                    "type": "synonym"
                },
                {
                    "name": "Synovial sarcoma, X breakpoint 1",
                    "type": "synonym"
                },
                {
                    "name": "cancer/testis antigen 5.1",
                    "type": "synonym"
                },
                {
                    "name": "cancer/testis antigen family 5, member 1",
                    "type": "synonym"
                },
                {
                    "name": "protein SSX1",
                    "type": "synonym"
                },
                {
                    "name": "sarcoma, synovial, X-chromosome-related 1",
                    "type": "synonym"
                },
                {
                    "name": "synovial sarcoma, X breakpoint 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "SSX1",
                    "type": "recommended"
                },
                {
                    "name": "CT5.1",
                    "type": "synonym"
                },
                {
                    "name": "SPGFX5",
                    "type": "synonym"
                },
                {
                    "name": "SSRC",
                    "type": "synonym"
                },
                {
                    "name": "SSX1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q16384-1",
            "evidence": [
                {
                    "id": "301099",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/301099"
                },
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "M0R5E6-1",
            "uniprot_ac": "M0R5E6",
            "uniprot_id": "M0R5E6_RAT",
            "refseq_ac": "XP_017457722",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "SSX family member 2",
                    "type": "synonym"
                },
                {
                    "name": "protein SSXA1-like",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ssx2",
                    "type": "recommended"
                },
                {
                    "name": "Ssx2",
                    "type": "synonym"
                }
            ],
            "record_id": "M0R5E6-1",
            "evidence": [
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "F1M0F5-1",
            "uniprot_ac": "F1M0F5",
            "uniprot_id": "F1M0F5_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "SSX family member 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ssx1",
                    "type": "recommended"
                }
            ],
            "record_id": "F1M0F5-1",
            "evidence": [
                {
                    "id": "0070596",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070596"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0070596"
}