{
    "disease_id": "DOID:0070591",
    "recommended_name": {
        "id": "DOID:0070591",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0070591",
        "name": "spermatogenic failure 92",
        "description": "A spermatogenic failure characterized by asthenozoospermia that has_material_basis_in homozygous mutation in the LRRC23 gene on chromosome 12p13.31."
    },
    "synonyms": [
        {
            "id": "DOID:0070591",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070591",
            "name": "SPGF92",
            "description": ""
        },
        {
            "id": "MONDO:0970999",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0970999",
            "name": "spermatogenic failure 92",
            "description": ""
        },
        {
            "id": "MIM:620848",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/620848",
            "name": "Spermatogenic failure 92",
            "description": "Spermatogenic failure 92"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0070591"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0070591",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070591",
            "categories": []
        },
        {
            "id": "MONDO:0970999",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0970999",
            "categories": []
        },
        {
            "id": "MIM:620848",
            "database": "MIM",
            "url": "https://www.omim.org/entry/620848",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "A0AC58IJL8-1",
            "uniprot_ac": "A0AC58IJL8",
            "uniprot_id": "A0AC58IJL8_DANRE",
            "refseq_ac": "XP_073794429",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Danio rerio",
                    "taxid": 7955,
                    "common_name": "Zebrafish",
                    "glygen_name": "Zebrafish",
                    "reference_species": "Danio rerio [7955]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat-containing protein 23",
                    "type": "recommended"
                },
                {
                    "name": "leucine-rich repeat-containing protein 23 isoform X1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "lrrc23",
                    "type": "recommended"
                },
                {
                    "name": "lrrc23",
                    "type": "synonym"
                },
                {
                    "name": "zgc:101782",
                    "type": "synonym"
                }
            ],
            "record_id": "A0AC58IJL8-1",
            "evidence": [
                {
                    "id": "0070591",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070591"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "O35125-1",
            "uniprot_ac": "O35125",
            "uniprot_id": "LRC23_MOUSE",
            "refseq_ac": "NP_001289484",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat-containing protein 23",
                    "type": "recommended"
                },
                {
                    "name": "Leucine-rich protein B7",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich protein B7",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing protein 23",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Lrrc23",
                    "type": "recommended"
                },
                {
                    "name": "4921537K05Rik",
                    "type": "synonym"
                },
                {
                    "name": "B7",
                    "type": "synonym"
                },
                {
                    "name": "Lrpb7",
                    "type": "synonym"
                },
                {
                    "name": "Lrrc23",
                    "type": "synonym"
                }
            ],
            "record_id": "O35125-1",
            "evidence": [
                {
                    "id": "0070591",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070591"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q53EV4-1",
            "uniprot_ac": "Q53EV4",
            "uniprot_id": "LRC23_HUMAN",
            "refseq_ac": "NP_001128689",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat-containing protein 23",
                    "type": "recommended"
                },
                {
                    "name": "Leucine-rich protein B7",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich protein B7",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing protein 23 isoform a",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing protein 23",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "LRRC23",
                    "type": "recommended"
                },
                {
                    "name": "LRPB7",
                    "type": "synonym"
                },
                {
                    "name": "LRRC23",
                    "type": "synonym"
                },
                {
                    "name": "SPGF92",
                    "type": "synonym"
                }
            ],
            "record_id": "Q53EV4-1",
            "evidence": [
                {
                    "id": "620848",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/620848"
                },
                {
                    "id": "0070591",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070591"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "G3V9K7-1",
            "uniprot_ac": "G3V9K7",
            "uniprot_id": "G3V9K7_RAT",
            "refseq_ac": "NP_001381276",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Leucine-rich repeat-containing protein 23",
                    "type": "recommended"
                },
                {
                    "name": "Leucine-rich protein B7",
                    "type": "synonym"
                },
                {
                    "name": "leucine rich protein, B7",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing protein 23-like",
                    "type": "synonym"
                },
                {
                    "name": "leucine-rich repeat-containing protein 23",
                    "type": "synonym"
                },
                {
                    "name": "neuron-specific enolase",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Lrrc23",
                    "type": "recommended"
                },
                {
                    "name": "Lrpb7",
                    "type": "synonym"
                },
                {
                    "name": "Lrrc23",
                    "type": "synonym"
                }
            ],
            "record_id": "G3V9K7-1",
            "evidence": [
                {
                    "id": "0070591",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070591"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0070591"
}