{
    "disease_id": "DOID:0070590",
    "recommended_name": {
        "id": "DOID:0070590",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0070590",
        "name": "spermatogenic failure 91",
        "description": "A spermatogenic failure characterized by teratozoospermia, consisting of a misshapen rounded sperm head and detachment of the acrosome, and sperm that fail to attach to the zona pellucida that has_material_basis_in homozygous or compound heterozygous mutation in the CCIN gene on chromosome 9p13.3."
    },
    "synonyms": [
        {
            "id": "DOID:0070590",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070590",
            "name": "SPGF91",
            "description": ""
        },
        {
            "id": "MONDO:0970952",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0970952",
            "name": "spermatogenic failure 91",
            "description": ""
        },
        {
            "id": "MIM:620838",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/620838",
            "name": "Spermatogenic failure 91",
            "description": "Spermatogenic failure 91"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0070590"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0070590",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070590",
            "categories": []
        },
        {
            "id": "MONDO:0970952",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0970952",
            "categories": []
        },
        {
            "id": "MIM:620838",
            "database": "MIM",
            "url": "https://www.omim.org/entry/620838",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q8CDE2-1",
            "uniprot_ac": "Q8CDE2",
            "uniprot_id": "CALI_MOUSE",
            "refseq_ac": "NP_001002787",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Calicin",
                    "type": "recommended"
                },
                {
                    "name": "calicin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ccin",
                    "type": "recommended"
                },
                {
                    "name": "4933417A14Rik",
                    "type": "synonym"
                },
                {
                    "name": "Ccin",
                    "type": "synonym"
                }
            ],
            "record_id": "Q8CDE2-1",
            "evidence": [
                {
                    "id": "0070590",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070590"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q13939-1",
            "uniprot_ac": "Q13939",
            "uniprot_id": "CALI_HUMAN",
            "refseq_ac": "NP_005884",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Calicin",
                    "type": "recommended"
                },
                {
                    "name": "calicin",
                    "type": "synonym"
                },
                {
                    "name": "testis tissue sperm-binding protein Li 65n",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "CCIN",
                    "type": "recommended"
                },
                {
                    "name": "BTBD20",
                    "type": "synonym"
                },
                {
                    "name": "CCIN",
                    "type": "synonym"
                },
                {
                    "name": "KBTBD14",
                    "type": "synonym"
                },
                {
                    "name": "SPGF91",
                    "type": "synonym"
                }
            ],
            "record_id": "Q13939-1",
            "evidence": [
                {
                    "id": "620838",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/620838"
                },
                {
                    "id": "0070590",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070590"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q5XI58-1",
            "uniprot_ac": "Q5XI58",
            "uniprot_id": "CALI_RAT",
            "refseq_ac": "NP_001005904",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Calicin",
                    "type": "recommended"
                },
                {
                    "name": "calicin",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Ccin",
                    "type": "recommended"
                },
                {
                    "name": "Ccin",
                    "type": "synonym"
                }
            ],
            "record_id": "Q5XI58-1",
            "evidence": [
                {
                    "id": "0070590",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070590"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0070590"
}