{
    "disease_id": "DOID:0070584",
    "recommended_name": {
        "id": "DOID:0070584",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0070584",
        "name": "spermatogenic failure 85",
        "description": "A spermatogenic failure characterized by globozoospermia and reduced progressive motility that has_material_basis_in homozygous mutation in the SPACA1 gene on chromosome 6q15."
    },
    "synonyms": [
        {
            "id": "DOID:0070584",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070584",
            "name": "SPGF85",
            "description": ""
        },
        {
            "id": "MONDO:0957584",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957584",
            "name": "spermatogenic failure 85",
            "description": ""
        },
        {
            "id": "MIM:620490",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/620490",
            "name": "Spermatogenic failure 85",
            "description": "Spermatogenic failure 85"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0070584"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0070584",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0070584",
            "categories": []
        },
        {
            "id": "MONDO:0957584",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957584",
            "categories": []
        },
        {
            "id": "MIM:620490",
            "database": "MIM",
            "url": "https://www.omim.org/entry/620490",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q9DA48-1",
            "uniprot_ac": "Q9DA48",
            "uniprot_id": "SACA1_MOUSE",
            "refseq_ac": "NP_080569",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Sperm acrosome membrane-associated protein 1",
                    "type": "recommended"
                },
                {
                    "name": "sperm acrosome membrane-associated protein 1 isoform 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "sperm acrosome membrane-associated protein 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Spaca1",
                    "type": "recommended"
                },
                {
                    "name": "1700124L11Rik",
                    "type": "synonym"
                },
                {
                    "name": "4930540L03Rik",
                    "type": "synonym"
                },
                {
                    "name": "Spaca1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9DA48-1",
            "evidence": [
                {
                    "id": "0070584",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070584"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q9HBV2-1",
            "uniprot_ac": "Q9HBV2",
            "uniprot_id": "SACA1_HUMAN",
            "refseq_ac": "NP_112222",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Sperm acrosome membrane-associated protein 1",
                    "type": "recommended"
                },
                {
                    "name": "Sperm acrosomal membrane-associated protein 32",
                    "type": "synonym"
                },
                {
                    "name": "sperm acrosomal membrane-associated protein 32",
                    "type": "synonym"
                },
                {
                    "name": "sperm acrosome membrane-associated protein 1 precursor",
                    "type": "synonym"
                },
                {
                    "name": "sperm acrosome membrane-associated protein 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "SPACA1",
                    "type": "recommended"
                },
                {
                    "name": "SAMP32",
                    "type": "synonym"
                },
                {
                    "name": "SPACA1",
                    "type": "synonym"
                },
                {
                    "name": "SPGF85",
                    "type": "synonym"
                }
            ],
            "record_id": "Q9HBV2-1",
            "evidence": [
                {
                    "id": "620490",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/620490"
                },
                {
                    "id": "0070584",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070584"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "D3Z9F9-1",
            "uniprot_ac": "D3Z9F9",
            "uniprot_id": "D3Z9F9_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Sperm acrosome associated 1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Spaca1",
                    "type": "recommended"
                }
            ],
            "record_id": "D3Z9F9-1",
            "evidence": [
                {
                    "id": "0070584",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0070584"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0070584"
}