{
    "disease_id": "DOID:0060928",
    "recommended_name": {
        "id": "DOID:0060928",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0060928",
        "name": "otosclerosis 11",
        "description": "An otosclerosis that is characterized by onset of progressive hearing loss in the second to third decade of life and that has_material_basis_in the locus associated with Forkhead Box L1 gene (FOXL1) on chromosome 16q24."
    },
    "synonyms": [
        {
            "id": "DOID:0060928",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060928",
            "name": "OTSC11",
            "description": ""
        },
        {
            "id": "MONDO:0957928",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957928",
            "name": "otosclerosis 11",
            "description": ""
        },
        {
            "id": "MIM:620576",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/620576",
            "name": "Otosclerosis 11",
            "description": "Otosclerosis 11"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0060928"
    ],
    "unlinked_id_list": [],
    "crossref": [
        {
            "id": "DOID:0060928",
            "database": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0060928",
            "categories": []
        },
        {
            "id": "MONDO:0957928",
            "database": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0957928",
            "categories": []
        },
        {
            "id": "MIM:620576",
            "database": "MIM",
            "url": "https://www.omim.org/entry/620576",
            "categories": []
        }
    ],
    "proteins": [
        {
            "uniprot_canonical_ac": "Q64731-1",
            "uniprot_ac": "Q64731",
            "uniprot_id": "FOXL1_MOUSE",
            "refseq_ac": "NP_032050",
            "glycoprotein": "yes",
            "species": [
                {
                    "name": "Mus musculus",
                    "taxid": 10090,
                    "common_name": "Mouse",
                    "glygen_name": "Mouse",
                    "reference_species": "Mus musculus [10090]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein L1",
                    "type": "recommended"
                },
                {
                    "name": "Forkhead-related protein FKHL11",
                    "type": "synonym"
                },
                {
                    "name": "Transcription factor FKH-6",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein L1",
                    "type": "synonym"
                },
                {
                    "name": "forkhead homolog 6",
                    "type": "synonym"
                },
                {
                    "name": "forkhead-related protein FKHL11",
                    "type": "synonym"
                },
                {
                    "name": "transcription factor FKH-6",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Foxl1",
                    "type": "recommended"
                },
                {
                    "name": "FREAC7",
                    "type": "synonym"
                },
                {
                    "name": "Fkh6",
                    "type": "synonym"
                },
                {
                    "name": "Fkhl11",
                    "type": "synonym"
                },
                {
                    "name": "Foxl1",
                    "type": "synonym"
                },
                {
                    "name": "fkh-6",
                    "type": "synonym"
                }
            ],
            "record_id": "Q64731-1",
            "evidence": [
                {
                    "id": "0060928",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060928"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q12952-1",
            "uniprot_ac": "Q12952",
            "uniprot_id": "FOXL1_HUMAN",
            "refseq_ac": "NP_005241",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Homo sapiens",
                    "taxid": 9606,
                    "common_name": "Human",
                    "glygen_name": "Human",
                    "reference_species": "Homo sapiens [9606]"
                }
            ],
            "protein_names": [
                {
                    "name": "Forkhead box protein L1",
                    "type": "recommended"
                },
                {
                    "name": "FREAC-7",
                    "type": "synonym"
                },
                {
                    "name": "Forkhead-related protein FKHL11",
                    "type": "synonym"
                },
                {
                    "name": "Forkhead-related transcription factor 7",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box protein L1",
                    "type": "synonym"
                },
                {
                    "name": "forkhead-like 11",
                    "type": "synonym"
                },
                {
                    "name": "forkhead-related protein FKHL11",
                    "type": "synonym"
                },
                {
                    "name": "forkhead-related transcription factor 7",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FOXL1",
                    "type": "recommended"
                },
                {
                    "name": "FKH6",
                    "type": "synonym"
                },
                {
                    "name": "FKHL11",
                    "type": "synonym"
                },
                {
                    "name": "FOXL1",
                    "type": "synonym"
                },
                {
                    "name": "FREAC7",
                    "type": "synonym"
                },
                {
                    "name": "OTSC11",
                    "type": "synonym"
                }
            ],
            "record_id": "Q12952-1",
            "evidence": [
                {
                    "id": "620576",
                    "database": "MIM",
                    "url": "https://www.omim.org/entry/620576"
                },
                {
                    "id": "0060928",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060928"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P40466-1",
            "uniprot_ac": "P40466",
            "uniprot_id": "FKH1_YEAST",
            "refseq_ac": "NP_012135",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Saccharomyces cerevisiae S288C",
                    "taxid": 559292,
                    "common_name": "Baker's yeast",
                    "glygen_name": "Yeast",
                    "reference_species": "Saccharomyces cerevisiae S288C [559292]"
                }
            ],
            "protein_names": [
                {
                    "name": "Fork head protein homolog 1",
                    "type": "recommended"
                },
                {
                    "name": "forkhead family transcription factor FKH1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FKH1",
                    "type": "recommended"
                },
                {
                    "name": "FKH1",
                    "type": "synonym"
                }
            ],
            "record_id": "P40466-1",
            "evidence": [
                {
                    "id": "0060928",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060928"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "P36370-1",
            "uniprot_ac": "P36370",
            "uniprot_id": "TAP1_RAT",
            "refseq_ac": "",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Rattus norvegicus",
                    "taxid": 10116,
                    "common_name": "Rat",
                    "glygen_name": "Rat",
                    "reference_species": "Rattus norvegicus [10116]"
                }
            ],
            "protein_names": [
                {
                    "name": "Antigen peptide transporter 1",
                    "type": "recommended"
                },
                {
                    "name": "7.4.2.14",
                    "type": "synonym"
                },
                {
                    "name": "APT1",
                    "type": "synonym"
                },
                {
                    "name": "ATP-binding cassette sub-family B member 2",
                    "type": "synonym"
                },
                {
                    "name": "Peptide transporter TAP1",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "Tap1",
                    "type": "recommended"
                },
                {
                    "name": "Abcb2",
                    "type": "synonym"
                },
                {
                    "name": "Mtp1",
                    "type": "synonym"
                }
            ],
            "record_id": "P36370-1",
            "evidence": [
                {
                    "id": "0060928",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060928"
                }
            ]
        },
        {
            "uniprot_canonical_ac": "Q02360-1",
            "uniprot_ac": "Q02360",
            "uniprot_id": "FOXL1_DROME",
            "refseq_ac": "NP_001246609",
            "glycoprotein": "no",
            "species": [
                {
                    "name": "Drosophila melanogaster",
                    "taxid": 7227,
                    "common_name": "Fruit fly",
                    "glygen_name": "Fruit fly",
                    "reference_species": "Drosophila melanogaster [7227]"
                }
            ],
            "protein_names": [
                {
                    "name": "Fork head domain-containing protein L1",
                    "type": "recommended"
                },
                {
                    "name": "CG1132-PB",
                    "type": "synonym"
                },
                {
                    "name": "FoxL1-PB",
                    "type": "synonym"
                },
                {
                    "name": "forkhead box L1, isoform B",
                    "type": "synonym"
                },
                {
                    "name": "forkhead domain 64A",
                    "type": "synonym"
                }
            ],
            "gene_names": [
                {
                    "name": "FoxL1",
                    "type": "recommended"
                },
                {
                    "name": "CG1132",
                    "type": "synonym"
                },
                {
                    "name": "Dmel\\CG1132",
                    "type": "synonym"
                },
                {
                    "name": "Dmfd2",
                    "type": "synonym"
                },
                {
                    "name": "FD2",
                    "type": "synonym"
                },
                {
                    "name": "Fd64A",
                    "type": "synonym"
                },
                {
                    "name": "FoxL1",
                    "type": "synonym"
                },
                {
                    "name": "fd2",
                    "type": "synonym"
                },
                {
                    "name": "fd64A",
                    "type": "synonym"
                },
                {
                    "name": "foxL1",
                    "type": "synonym"
                }
            ],
            "record_id": "Q02360-1",
            "evidence": [
                {
                    "id": "0060928",
                    "database": "AGR",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060928"
                }
            ]
        }
    ],
    "glycans": [],
    "biomarkers": [],
    "association_flag": "1000",
    "record_id": "doid.0060928"
}