{
    "biomarker_id": "BB3851-2",
    "biomarker_canonical_id": "BB3851",
    "condition": {
        "recommended_name": {
            "id": "DOID:1495",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:1495",
            "name": "cystic echinococcosis",
            "description": "An echinococcosis that is caused by the larvae of Echinococcus granulosus. Hepatic involvement can result in abdominal pain, a mass in the hepatic area, and biliary duct obstruction. Pulmonary involvement can produce chest pain, cough, and hemoptysis. Rupture of the cysts produce fever, urticaria, eosinophilia, and anaphylactic shock, as well as cyst dissemination. Brain, bone, heart can also be infected."
        },
        "synonyms": [
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "echinococcus granulosus infectious disease of thyroid",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "Echinococcus granulosus infection",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "Echinococcus granulosus infection of lung",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "Echinococcus granulosus infection of thyroid",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "Liver echinococcus granulosus",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "Thyroid echinococcus granulosus",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "echinococcus granulosus",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "echinococcus granulosus infectious disease",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "lung echinococcus granulosus",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "unilocular echinococcosis",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "unilocular hydatid disease",
                "description": ""
            },
            {
                "id": "DOID:1495",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1495",
                "name": "echinococcus granulosus infectious disease of liver",
                "description": ""
            }
        ],
        "id": "DOID:1495"
    },
    "biomarker_component": [
        {
            "biomarker": "increased level of agalactosylated on immunoglobulin G",
            "assessed_biomarker_entity_id": "P01825-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Immunoglobulin heavy variable 4-59",
                "synonyms": [
                    {
                        "synonym": "Ig heavy chain V-II region NEWM"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood serum",
                    "namespace": "UBERON",
                    "id": "0001977",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0001977",
                    "loinc_code": ""
                }
            ],
            "evidence_source": [
                {
                    "id": "BB3851-2",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/BB3851-2"
                },
                {
                    "id": "40200705",
                    "database": "PubMed",
                    "url": "",
                    "tags": [
                        "assessed_biomarker_entity_id",
                        " assessed_biomarker_entiy",
                        " assessed_entity_type",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "The relative quantification of IgG digalactosylated (G2), monogalactosylated (G1), and agalactosylated (G0) N-glycans with the formula G0/(G1 + G2 \u00d7 2) (IgG Gal-ratio) was obtained and found to effectively distinguish between echinococcosis patients, CE and AE patients, and healthy controls, respectively. Meanwhile, the IgG Gal-ratio was evidently related to different types of CE (from CE1 to CE5) and the follow-up CE disease progress."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": ""
        }
    ],
    "evidence_source": [
        {
            "id": "BB3851-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/BB3851-2"
        },
        {
            "id": "40200705",
            "database": "PubMed",
            "url": "",
            "tags": [
                "condition"
            ],
            "evidence_list": [
                {
                    "evidence": "The relative quantification of IgG digalactosylated (G2), monogalactosylated (G1), and agalactosylated (G0) N-glycans with the formula G0/(G1 + G2 \u00d7 2) (IgG Gal-ratio) was obtained and found to effectively distinguish between echinococcosis patients, CE and AE patients, and healthy controls, respectively. Meanwhile, the IgG Gal-ratio was evidently related to different types of CE (from CE1 to CE5) and the follow-up CE disease progress."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "BB3851-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/BB3851-2",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "biomarker",
                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                }
            ],
            "sort_fields": []
        }
    ]
}
