{
    "biomarker_id": "AN6702-1",
    "biomarker_canonical_id": "AN6702",
    "condition": {
        "recommended_name": {
            "id": "DOID:4159",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:4159",
            "name": "skin cancer",
            "description": "An integumentary system cancer located_in the skin that is the uncontrolled growth of abnormal skin cells."
        },
        "synonyms": [
            {
                "id": "DOID:4159",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:4159",
                "name": "CA - skin cancer",
                "description": ""
            },
            {
                "id": "DOID:4159",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:4159",
                "name": "malignant neoplasm of skin",
                "description": ""
            },
            {
                "id": "DOID:4159",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:4159",
                "name": "melanoma and Non-melanoma skin cancer",
                "description": ""
            }
        ],
        "id": "DOID:4159"
    },
    "biomarker_component": [
        {
            "biomarker": "increased SPAG9 level",
            "assessed_biomarker_entity_id": "O60271-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "C-Jun-amino-terminal kinase-interacting protein 4",
                "synonyms": [
                    {
                        "synonym": "Cancer/testis antigen 89"
                    },
                    {
                        "synonym": "CT89"
                    },
                    {
                        "synonym": "Protein highly expressed in testis"
                    },
                    {
                        "synonym": "PHET"
                    },
                    {
                        "synonym": "JNK-associated leucine-zipper protein"
                    },
                    {
                        "synonym": "JLP"
                    },
                    {
                        "synonym": "Human lung cancer oncogene 6 protein"
                    },
                    {
                        "synonym": "HLC-6"
                    },
                    {
                        "synonym": "Sperm-associated antigen 9"
                    },
                    {
                        "synonym": "Mitogen-activated protein kinase 8-interacting protein 4"
                    },
                    {
                        "synonym": "Sperm-specific protein"
                    },
                    {
                        "synonym": "Proliferation-inducing protein 6"
                    },
                    {
                        "synonym": "Sperm surface protein"
                    },
                    {
                        "synonym": "Sunday driver 1"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "skin epidermis",
                    "namespace": "UBERON",
                    "id": "0001003",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0001003",
                    "loinc_code": ""
                }
            ],
            "evidence_source": [
                {
                    "id": "AN6702-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6702-1"
                },
                {
                    "id": "25033008",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/25033008",
                    "tags": [
                        "assessed_biomarker_entity",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "SPAG9 was upregulated in NMSC when compared with normal skin. In conclusion, SPAG9 is expressed in NMSC cases."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "diagnostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6702-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6702-1"
        },
        {
            "id": "25033008",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/25033008",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "SPAG9 was upregulated in NMSC when compared with normal skin. In conclusion, SPAG9 is expressed in NMSC cases."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6702-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6702-1",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Immunohistochemical expression of sperm-associated antigen 9 in nonmelanoma skin cancer.",
            "journal": "The American Journal of dermatopathology",
            "authors": "Seleit I, Bakry OA, Samaka RM, Malak MA",
            "date": "2015",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "25033008",
                    "url": "https://glygen.org/publication/PubMed/25033008"
                }
            ],
            "evidence": [
                {
                    "id": "AN6701-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6702-1"
                }
            ]
        }
    ],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "biomarker",
                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "authors",
                "date"
            ]
        }
    ]
}