{
    "biomarker_id": "AN6680-1",
    "biomarker_canonical_id": "AN6680",
    "condition": {
        "recommended_name": {
            "id": "DOID:363",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:363",
            "name": "uterine cancer",
            "description": "A female reproductive organ cancer that is located_in the uterus."
        },
        "synonyms": [
            {
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                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:363",
                "name": "CA - cancer of uterus",
                "description": ""
            },
            {
                "id": "DOID:363",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:363",
                "name": "Tumour of uterus",
                "description": ""
            },
            {
                "id": "DOID:363",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:363",
                "name": "malignant neoplasm of uterus",
                "description": ""
            },
            {
                "id": "DOID:363",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:363",
                "name": "malignant uterine tumor",
                "description": ""
            },
            {
                "id": "DOID:363",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:363",
                "name": "neoplasm of uterus",
                "description": ""
            },
            {
                "id": "DOID:363",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:363",
                "name": "uterine tumor",
                "description": ""
            },
            {
                "id": "DOID:363",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:363",
                "name": "uterus neoplasm",
                "description": ""
            }
        ],
        "id": "DOID:363"
    },
    "biomarker_component": [
        {
            "biomarker": "increased TAGLN level",
            "assessed_biomarker_entity_id": "Q01995-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Transgelin",
                "synonyms": [
                    {
                        "synonym": "Smooth muscle protein 22-alpha"
                    },
                    {
                        "synonym": "SM22-alpha"
                    },
                    {
                        "synonym": "Protein WS3-10"
                    },
                    {
                        "synonym": "22 kDa actin-binding protein"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "smooth muscle tissue",
                    "namespace": "UBERON",
                    "id": "0001135",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0001135",
                    "loinc_code": ""
                }
            ],
            "evidence_source": [
                {
                    "id": "AN6680-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6680-1"
                },
                {
                    "id": "23174934",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/23174934",
                    "tags": [
                        "assessed_biomarker_entity",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "For the diagnosis of leiomyosarcomas versus all other sarcomas including GIST, transgelin emerged as the best diagnostic marker with 83% Se, 82% Sp, a PPV of 67%, a NPV of 92% and an accuracy rate of 83%."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "diagnostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6680-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6680-1"
        },
        {
            "id": "23174934",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/23174934",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "For the diagnosis of leiomyosarcomas versus all other sarcomas including GIST, transgelin emerged as the best diagnostic marker with 83% Se, 82% Sp, a PPV of 67%, a NPV of 92% and an accuracy rate of 83%."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6680-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6680-1",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Transgelin is a novel marker of smooth muscle differentiation that improves diagnostic accuracy of leiomyosarcomas: a comparative immunohistochemical reappraisal of myogenic markers in 900 soft tissue tumors.",
            "journal": "Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc",
            "authors": "Robin Yves-Marie, Penel Nicolas, P\u00e9rot Ga\u00eblle, Neuville Agnes, V\u00e9lasco Val\u00e9rie, Ranch\u00e8re-Vince Dominique, Terrier Philippe, Coindre Jean-Michel",
            "date": "2013-04",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "23174934",
                    "url": "https://glygen.org/publication/PubMed/23174934"
                }
            ],
            "evidence": [
                {
                    "id": "AN6679-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6680-1"
                }
            ]
        }
    ],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
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                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
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                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
            "table_stats": [
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                    "count": 1
                }
            ],
            "sort_fields": [
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                "journal",
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}