{
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    "biomarker_canonical_id": "AN6501",
    "condition": {
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            "id": "DOID:1781",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:1781",
            "name": "thyroid cancer",
            "description": "An endocrine gland cancer located in the thyroid gland located in the neck below the thyroid cartilage."
        },
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            {
                "id": "DOID:1781",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1781",
                "name": "Thyroid gland neoplasm",
                "description": ""
            },
            {
                "id": "DOID:1781",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1781",
                "name": "malignant neoplasm of thyroid gland",
                "description": ""
            },
            {
                "id": "DOID:1781",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1781",
                "name": "malignant tumour of thyroid gland",
                "description": ""
            },
            {
                "id": "DOID:1781",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1781",
                "name": "neoplasm of thyroid gland",
                "description": ""
            },
            {
                "id": "DOID:1781",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1781",
                "name": "thyroid neoplasm",
                "description": ""
            },
            {
                "id": "DOID:1781",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:1781",
                "name": "thyroid gland cancer",
                "description": ""
            }
        ],
        "id": "DOID:1781"
    },
    "biomarker_component": [
        {
            "biomarker": "increased CHI3L1 level",
            "assessed_biomarker_entity_id": "P36222-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Chitinase-3-like protein 1",
                "synonyms": [
                    {
                        "synonym": "Cartilage glycoprotein 39"
                    },
                    {
                        "synonym": "CGP-39"
                    },
                    {
                        "synonym": "GP-39"
                    },
                    {
                        "synonym": "hCGP-39"
                    },
                    {
                        "synonym": "YKL-40"
                    },
                    {
                        "synonym": "39 kDa synovial protein"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "thyroid gland",
                    "namespace": "UBERON",
                    "id": "0002046",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0002046",
                    "loinc_code": ""
                }
            ],
            "evidence_source": [
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                    "url": "https://glygen.org/publication/PubMed/32613636",
                    "tags": [
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                    ],
                    "evidence_list": [
                        {
                            "evidence": "Here, we investigated the prognostic significance of CHI3L1 expression in thyroid neoplasms and examined the potential oncogenic roles. Compared with normal thyroid tissue and benign thyroid lesions that had low or no detectable CHI3L1 expression, CHI3L1 was overexpressed in both differentiated and undifferentiated thyroid cancer."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "prognostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6501-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6501-2"
        },
        {
            "id": "32613636",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/32613636",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "Here, we investigated the prognostic significance of CHI3L1 expression in thyroid neoplasms and examined the potential oncogenic roles. Compared with normal thyroid tissue and benign thyroid lesions that had low or no detectable CHI3L1 expression, CHI3L1 was overexpressed in both differentiated and undifferentiated thyroid cancer."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6501-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6501-2",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Overexpression of chitinase-3-like protein 1 is associated with structural recurrence in patients with differentiated thyroid cancer.",
            "journal": "The Journal of pathology",
            "authors": "Cheng SP, Lee JJ, Chang YC, Lin CH, Li YS, Liu CL",
            "date": "2020",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "32613636",
                    "url": "https://glygen.org/publication/PubMed/32613636"
                }
            ],
            "evidence": [
                {
                    "id": "AN6501-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6501-2"
                }
            ]
        }
    ],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
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                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
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                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
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}