{
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                "id": "MONDO:0008903",
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                "id": "MONDO:0008903",
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                "id": "MONDO:0008903",
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                "id": "MONDO:0008903",
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                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
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                "name": "malignant tumour of the lung",
                "description": ""
            },
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                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation",
                "description": ""
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                "id": "MONDO:0008903",
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                "description": ""
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                "description": ""
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                "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                "name": "lung cancer susceptibility 1",
                "description": ""
            },
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                "id": "MONDO:0012159",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                "name": "LNCR1",
                "description": ""
            },
            {
                "id": "MONDO:0012159",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                "name": "lung cancer susceptibility",
                "description": ""
            },
            {
                "id": "MONDO:0012159",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                "name": "lung cancer susceptibility 1",
                "description": ""
            },
            {
                "id": "MONDO:0012942",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                "name": "lung cancer susceptibility 3",
                "description": ""
            },
            {
                "id": "MONDO:0012942",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                "name": "LNCR3",
                "description": ""
            },
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                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012942",
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                "description": ""
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                "id": "MONDO:0012955",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012955",
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                "description": ""
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                "description": ""
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                "url": "https://monarchinitiative.org/disease/MONDO:0012955",
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                "description": ""
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                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                "name": "lung cancer susceptibility 5",
                "description": ""
            },
            {
                "id": "MONDO:0013631",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                "name": "LNCR5",
                "description": ""
            },
            {
                "id": "MONDO:0013631",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                "name": "lung cancer susceptibility 5",
                "description": ""
            },
            {
                "id": "MIM:211980",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/211980",
                "name": "Lung cancer",
                "description": "Lung cancer"
            }
        ],
        "id": "DOID:1324"
    },
    "biomarker_component": [
        {
            "biomarker": "increased CIT-H3 level",
            "assessed_biomarker_entity_id": "P68431-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Histone H3.1",
                "synonyms": [
                    {
                        "synonym": "Histone H3/h"
                    },
                    {
                        "synonym": "Histone H3/b"
                    },
                    {
                        "synonym": "Histone H3/d"
                    },
                    {
                        "synonym": "Histone H3/a"
                    },
                    {
                        "synonym": "Histone H3/i"
                    },
                    {
                        "synonym": "Histone H3/k"
                    },
                    {
                        "synonym": "Histone H3/f"
                    },
                    {
                        "synonym": "Histone H3/l"
                    },
                    {
                        "synonym": "Histone H3/c"
                    },
                    {
                        "synonym": "Histone H3/j"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood",
                    "namespace": "UBERON",
                    "id": "0000178",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
                    "loinc_code": ""
                }
            ],
            "evidence_source": [
                {
                    "id": "AN6379-2",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6379-2"
                },
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                    "tags": [
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                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "Our results are the first to unveil H3Cit as a potential diagnostic and prognostic blood marker associated with an exacerbated inflammatory response in patients with advanced cancer."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "prognostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6379-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6379-2"
        },
        {
            "id": "29324871",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/29324871",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "Our results are the first to unveil H3Cit as a potential diagnostic and prognostic blood marker associated with an exacerbated inflammatory response in patients with advanced cancer."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6379-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6379-2",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Citrullinated histone H3 as a novel prognostic blood marker in patients with advanced cancer.",
            "journal": "PloS one",
            "authors": "Th\u00e5lin Charlotte, Lundstr\u00f6m Staffan, Seignez Cedric, Daleskog Maud, Lundstr\u00f6m Annika, Henriksson Peter, Helleday Thomas, Phillipson Mia, Wall\u00e9n H\u00e5kan, Demers M\u00e9lanie",
            "date": "2018",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "29324871",
                    "url": "https://glygen.org/publication/PubMed/29324871"
                }
            ],
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                {
                    "id": "AN6379-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6379-2"
                }
            ]
        }
    ],
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}