{
    "biomarker_id": "AN6352-2",
    "biomarker_canonical_id": "AN6352",
    "condition": {
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            {
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            },
            {
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                "name": "gastric neoplasm",
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            },
            {
                "id": "MONDO:0001056",
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                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
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                "name": "GC",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
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                "description": ""
            },
            {
                "id": "MONDO:0001056",
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                "description": ""
            },
            {
                "id": "MONDO:0001056",
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                "name": "gastric cancer risk after h. pylori infection",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
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                "description": ""
            },
            {
                "id": "MONDO:0001056",
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                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant gastric neoplasm",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant gastric tumor",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant gastric tumour",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant neoplasm of lesser curve of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant neoplasm of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant neoplasm of the stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant stomach neoplasm",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumor of body of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumor of greater curve of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumor of lesser curve of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumor of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
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                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumor of the stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
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                "name": "malignant tumour of body of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumour of greater curve of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumour of lesser curve of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumour of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant tumour of the stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "stomach cancer",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "Ca body - stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "ca greater curvature of stomach",
                "description": ""
            },
            {
                "id": "MONDO:0001056",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                "name": "malignant neoplasm of body of stomach",
                "description": ""
            },
            {
                "id": "MIM:613659",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/613659",
                "name": "Gastric cancer",
                "description": "Gastric cancer"
            }
        ],
        "id": "DOID:10534"
    },
    "biomarker_component": [
        {
            "biomarker": "increased IL-2R level",
            "assessed_biomarker_entity_id": "P01589-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Interleukin-2 receptor subunit alpha",
                "synonyms": [
                    {
                        "synonym": "p55"
                    },
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                        "synonym": "TAC antigen"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood",
                    "namespace": "UBERON",
                    "id": "0000178",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
                    "loinc_code": "76039-7"
                }
            ],
            "evidence_source": [
                {
                    "id": "AN6352-2",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6352-2"
                },
                {
                    "id": "11961349",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/11961349",
                    "tags": [
                        "assessed_biomarker_entity",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "In 6 cases with lymph node metastasis, serum soluble IL-2R levels were significantly higher than in those without lymph node metastasis. Five of these 6 cases demonstrated statistically significantly increased levels of serum soluble IL-2R suggesting serum soluble IL-2R as a predictor of lymph node metastasis in early gastric cancer."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "prognostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6352-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6352-2"
        },
        {
            "id": "11961349",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/11961349",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "In 6 cases with lymph node metastasis, serum soluble IL-2R levels were significantly higher than in those without lymph node metastasis. Five of these 6 cases demonstrated statistically significantly increased levels of serum soluble IL-2R suggesting serum soluble IL-2R as a predictor of lymph node metastasis in early gastric cancer."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6352-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6352-2",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Serum soluble interleukin-2 receptor as a predictor of lymph node metastasis in early gastric cancer.",
            "journal": "Digestive surgery",
            "authors": "Murakami Saburo, Sakata Hideto, Tsuji Yoshitaka, Okubo Kastuhiko, Hamada Setsuo, Hirayama Rennzo",
            "date": "2002",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11961349",
                    "url": "https://glygen.org/publication/PubMed/11961349"
                }
            ],
            "evidence": [
                {
                    "id": "AN6352-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6352-2"
                }
            ]
        }
    ],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
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                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
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                }
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}