{
    "biomarker_id": "AN6332-1",
    "biomarker_canonical_id": "AN6332",
    "condition": {
        "recommended_name": {
            "id": "DOID:1324",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:1324",
            "name": "lung cancer",
            "description": "A respiratory system cancer that is located_in the lung."
        },
        "synonyms": [
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
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            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "adenocarcinoma of lung, somatic",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
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                "name": "cancer of lung",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "lung cancer",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "lung cancer, protection against, autosomal dominant, somatic mutation",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "lung cancer, resistance to, autosomal dominant, somatic mutation",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "lung cancer, somatic",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant lung neoplasm",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant lung tumor",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant lung tumour",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant neoplasm of lung",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant neoplasm of the lung",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant tumor of lung",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant tumor of the lung",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant tumour of lung",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "malignant tumour of the lung",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "nonsmall cell lung cancer, somatic",
                "description": ""
            },
            {
                "id": "MONDO:0008903",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0008903",
                "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation",
                "description": ""
            },
            {
                "id": "MONDO:0012159",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                "name": "lung cancer susceptibility 1",
                "description": ""
            },
            {
                "id": "MONDO:0012159",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                "name": "LNCR1",
                "description": ""
            },
            {
                "id": "MONDO:0012159",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                "name": "lung cancer susceptibility",
                "description": ""
            },
            {
                "id": "MONDO:0012159",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012159",
                "name": "lung cancer susceptibility 1",
                "description": ""
            },
            {
                "id": "MONDO:0012942",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                "name": "lung cancer susceptibility 3",
                "description": ""
            },
            {
                "id": "MONDO:0012942",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                "name": "LNCR3",
                "description": ""
            },
            {
                "id": "MONDO:0012942",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012942",
                "name": "lung cancer susceptibility 3",
                "description": ""
            },
            {
                "id": "MONDO:0012955",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012955",
                "name": "lung cancer susceptibility 4",
                "description": ""
            },
            {
                "id": "MONDO:0012955",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012955",
                "name": "LNCR4",
                "description": ""
            },
            {
                "id": "MONDO:0012955",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0012955",
                "name": "lung cancer susceptibility 4",
                "description": ""
            },
            {
                "id": "MONDO:0013631",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                "name": "lung cancer susceptibility 5",
                "description": ""
            },
            {
                "id": "MONDO:0013631",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                "name": "LNCR5",
                "description": ""
            },
            {
                "id": "MONDO:0013631",
                "resource": "MONDO",
                "url": "https://monarchinitiative.org/disease/MONDO:0013631",
                "name": "lung cancer susceptibility 5",
                "description": ""
            },
            {
                "id": "MIM:211980",
                "resource": "MIM",
                "url": "https://www.omim.org/entry/211980",
                "name": "Lung cancer",
                "description": "Lung cancer"
            }
        ],
        "id": "DOID:1324"
    },
    "biomarker_component": [
        {
            "biomarker": "increased CSF3 level",
            "assessed_biomarker_entity_id": "P09919-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Granulocyte colony-stimulating factor",
                "synonyms": [
                    {
                        "synonym": "Pluripoietin"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood",
                    "namespace": "UBERON",
                    "id": "0000178",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
                    "loinc_code": "54458-5"
                }
            ],
            "evidence_source": [
                {
                    "id": "AN6332-1",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6332-1"
                },
                {
                    "id": "21431281",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/21431281",
                    "tags": [
                        "assessed_biomarker_entity",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "It was found that 12 patients had a white blood cell count increased beyond normal as well as a high G-CSF plasma level and the survival of these patients was shorter as compared to the rest of the patients."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "prognostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6332-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6332-1"
        },
        {
            "id": "21431281",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/21431281",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "It was found that 12 patients had a white blood cell count increased beyond normal as well as a high G-CSF plasma level and the survival of these patients was shorter as compared to the rest of the patients."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6332-1",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6332-1",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "Granulocyte colony-stimulating factor expression as a prognostic biomarker in non-small cell lung cancer.",
            "journal": "Oncology reports",
            "authors": "Stathopoulos GP, Armakolas A, Tranga T, Marinou H, Stathopoulos J, Chandrinou H",
            "date": "2011",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "21431281",
                    "url": "https://glygen.org/publication/PubMed/21431281"
                }
            ],
            "evidence": [
                {
                    "id": "AN6331-3",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6332-1"
                }
            ]
        }
    ],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "biomarker",
                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
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                    "count": 1
                }
            ],
            "sort_fields": [
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                "journal",
                "authors",
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        }
    ]
}
